MCID: TYL001
MIFTS: 30

Taylor's Syndrome

Categories: Reproductive diseases

Aliases & Classifications for Taylor's Syndrome

MalaCards integrated aliases for Taylor's Syndrome:

Name: Taylor's Syndrome 12 15
Pelvic Congestion Syndrome 12 70
Congestion-Fibrosis Syndrome 12
Taylor Syndrome 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9346
ICD9CM 34 625.5
SNOMED-CT 67 156027002
UMLS 70 C0152078

Summaries for Taylor's Syndrome

MalaCards based summary : Taylor's Syndrome, also known as pelvic congestion syndrome, is related to interstitial cystitis and varicose veins, and has symptoms including pain and other symptoms associated with female genital organs, mittelschmerz and unspecified symptom associated with female genital organs. An important gene associated with Taylor's Syndrome is TAC1 (Tachykinin Precursor 1), and among its related pathways/superpathways are Oncogenic MAPK signaling and Signaling by PTK6. The drugs Hesperidin and Ibuprofen have been mentioned in the context of this disorder.

Related Diseases for Taylor's Syndrome

Diseases related to Taylor's Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 interstitial cystitis 11.3
2 varicose veins 10.8
3 pelvic varices 10.6
4 venous insufficiency 10.5
5 varicocele 10.4
6 endometriosis 10.4
7 chronic pain 10.3
8 constipation 10.2
9 vaginal discharge 10.2
10 may-thurner syndrome 10.2
11 adenomyosis 10.1
12 body mass index quantitative trait locus 1 10.1
13 pelvic inflammatory disease 10.1
14 ovarian cyst 10.1
15 hemorrhoid 10.1
16 carbamazepine allergy 10.1 TAC1 CALCA
17 perianal hematoma 10.1 TAC1 CALCA
18 algoneurodystrophy 10.1 TAC1 CALCA
19 neurogenic arthropathy 10.1 TAC1 CALCA
20 plantar fasciitis 10.1 TAC1 CALCA
21 myofascial pain syndrome 10.1 TAC1 CALCA
22 causalgia 10.1 TAC1 CALCA
23 detrusor sphincter dyssynergia 10.1 TAC1 CALCA
24 epicondylitis 10.1 TAC1 CALCA
25 reflex sympathetic dystrophy 10.1 TAC1 CALCA
26 bursitis 10.1 TAC1 CALCA
27 vasomotor rhinitis 10.1 TAC1 CALCA
28 trigeminal nerve disease 10.1 TAC1 CALCA
29 trigeminal neuralgia 10.0 TAC1 CALCA
30 burning mouth syndrome 10.0 TAC1 CALCA
31 autonomic nervous system disease 10.0 TAC1 CALCA
32 somatoform disorder 10.0 TAC1 CALCA
33 complex regional pain syndrome 10.0 TAC1 CALCA
34 pain agnosia 10.0 TAC1 CALCA
35 agnosia 10.0 TAC1 CALCA
36 paine syndrome 10.0 TAC1 CALCA
37 proteinuria, chronic benign 10.0
38 chronic venous insufficiency 10.0
39 thrombosis 10.0
40 aortic dissection 10.0
41 portal vein thrombosis 10.0
42 allergic disease 10.0
43 prostatitis 10.0
44 vascular disease 10.0
45 cellulitis 10.0
46 leukorrhea 10.0
47 tricuspid valve insufficiency 10.0
48 infertility 10.0
49 osteoarthritis 10.0
50 ileus 10.0

Graphical network of the top 20 diseases related to Taylor's Syndrome:



Diseases related to Taylor's Syndrome

Symptoms & Phenotypes for Taylor's Syndrome

UMLS symptoms related to Taylor's Syndrome:


pain and other symptoms associated with female genital organs; mittelschmerz; unspecified symptom associated with female genital organs; other specified symptoms associated with female genital organs; female genital pain and other symptoms

Drugs & Therapeutics for Taylor's Syndrome

Drugs for Taylor's Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hesperidin Approved, Investigational Phase 4 520-26-3 53477767
2
Ibuprofen Approved Phase 4 15687-27-1 3672
3
Polidocanol Approved Phase 4 9002-92-0
4 Analgesics, Non-Narcotic Phase 4
5 Pharmaceutical Solutions Phase 4
6 Analgesics Phase 4
7 Sclerosing Solutions Phase 4
8 Cyclooxygenase Inhibitors Phase 4
9 Antirheumatic Agents Phase 4
10 Anti-Inflammatory Agents Phase 4
11 Anti-Inflammatory Agents, Non-Steroidal Phase 4
12
Salmon calcitonin Approved, Investigational 47931-85-1 16129616
13
Calcitonin gene-related peptide Investigational 83652-28-2
14 neurokinin A
15 Katacalcin
16
Substance P 33507-63-0 44359816
17 calcitonin
18 Hormones

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Endovascular Versus Medical Treatment for the Pelvic Congestion Syndrome Not yet recruiting NCT04358497 Phase 4 Diosmin / Hesperidin;Ibuprofen 400 mg
2 Duplex US in Pelvic Congestion Syndrome in Females Unknown status NCT03943381
3 MRI & MRV in Pelvic Congestion Syndrome in Females Unknown status NCT03252041
4 PrOspective, MultiCenter Study for the Evaluation of PerformanCe of the ArtVentive Medical Group Peripheral EndoLuminal OcclUsion SystemTM in the Treatment of Varicocele or Pelvic Congestion SynDromE - OCCLUDE I Unknown status NCT02033863
5 Fibered Platinum Coils vs Vascular Plugs in Pelvic Varices Embolization for the Treatment of Pelvic Congestion Syndrome Completed NCT02796092
6 Clinical Efficacy of Conservative Treatment in Female Patients With Plevic Congestion Syndrome Completed NCT04512443 Daflon
7 Study of the Role of Vasoactive Neuropeptides in the Genesis of Venous Pelvic Pain Recruiting NCT03921788
8 Multicentric Spanish Record of Pelvic Varicose Veins Treated With Vascular Plugs Type Amplatzer - Pelvic Congestion Syndrome: Study of Efficacy and Safety Recruiting NCT04115137
9 Ultrasound Evaluation of the Prevalence of Pelvic Congestion Syndrome in Patients With Endometriosis Recruiting NCT03568149
10 Assessment of Pain of Pelvic Congestion Syndrome Treated by Coils Embolization (SCVPC) Recruiting NCT04461860
11 Quantification of Pain Relief With Gonadal Vein Embolization for Pelvic Congestion Syndrome Recruiting NCT03794466
12 Embolization of Pelvic Varicosities in Patients With Pelvic Congestion Syndrome Terminated NCT03057067
13 Effectiveness of Embolization of Pelvic Veins in Treatment of Pelvic Congestion Syndrome Withdrawn NCT03165214

Search NIH Clinical Center for Taylor's Syndrome

Genetic Tests for Taylor's Syndrome

Anatomical Context for Taylor's Syndrome

Publications for Taylor's Syndrome

Articles related to Taylor's Syndrome:

(show top 50) (show all 256)
# Title Authors PMID Year
1
Nutcracker Phenomenon with Menorrhagia in a Woman with Marfan Syndrome. 61
33786109 2021
2
Vulvar Varicosities in an Adolescent Girl with Morbid Obesity: A Case Report. 61
33800092 2021
3
Shape memory polymer ovarian vein embolisation in a patient with nickel allergy. 61
33655366 2021
4
Current results of left gonadal vein transposition to treat Nutcracker Syndrome. 61
33737260 2021
5
Pelvic congestion syndrome: a still underdiagnosed cause of chronic pain in premenopausal women. 61
33567800 2021
6
Unusual cause of pelvic congestion syndrome: Agenesis of the common and external iliac veins. 61
33546820 2021
7
Female pelvic congestion syndrome: how can CT and MRI help in the management decision? 61
33252986 2021
8
Hemodynamic and Radiological Classification of Ovarian Veins System Insufficiency. 61
33567554 2021
9
Pelvic Congestion Syndrome. 61
33541587 2021
10
Pregnancy with Klippel-Trenaunay Syndrome: A Critical Case Report. 61
33397882 2021
11
Compressed Double Left Common Iliac Vein with Vein Spurs in a Patient with Pelvic Congestion Syndrome. 61
33426538 2021
12
A Case of Posterior Nutcracker Syndrome Revealed in the Aerospace Environment. 61
33357275 2021
13
Comparative analysis of the efficacy and safety of endovascular and endoscopic interventions on the gonadal veins in the treatment of pelvic congestion syndrome. 61
32464289 2021
14
Diagnostic value of pelvic venography in female patients with pelvic varicose veins and vulvar varicosities. 61
32594669 2020
15
Medicine and Phlebolymphology: Time to Change? 61
33353052 2020
16
Endovascular interventions in the treatment of pelvic congestion syndrome caused by May-Thurner syndrome. 61
32241734 2020
17
[Pelvic congestion syndrome]. 61
33112517 2020
18
Unique Case of Recurrent Pelvic Congestion Syndrome Treated with Median Sacral Vein Embolization. 61
32283303 2020
19
Pelvic vein embolization: an assessment of the readability and quality of online information for patients. 61
32886198 2020
20
Postembolization syndrome in endovascular interventions on the gonadal veins. 61
32932000 2020
21
Dual effects of a gonadotropin-releasing hormone agonist on an adolescent girl with pelvic congestion syndrome and precocious puberty: a case report. 61
32967508 2020
22
Comprehensive review of pelvic congestion syndrome: causes, symptoms, treatment options. 61
32487799 2020
23
Abdominal Magnetic Resonance Angiography. 61
32624157 2020
24
A Case Report of a Migrated Pelvic Coil Causing Pulmonary Infarct in an Adult Female. 61
32926706 2020
25
Salvage Renal Autotransplant Following Previous Renal Vein Stenting in Nutcracker Syndrome. 61
31104623 2020
26
Pelvic Congestion Syndrome Secondary to a Circumaortic Left Renal Vein. 61
32037151 2020
27
What family physicians should know about interventional radiology? 61
32831552 2020
28
The management of pelvic congestion syndrome - a word of caution. 61
31215286 2020
29
Venous ulcerations occur more frequently in women on the left lower leg. Can pelvic congestion syndrome be an often undetected cause? 61
31701627 2020
30
Does pelvic congestion syndrome influence symptoms of chronic venous disease of the lower extremities? 61
31675634 2019
31
Pelvic congestion syndrome and embolization of pelvic varicose veins. 61
31762775 2019
32
Outcomes of left renal vein stenting in patients with nutcracker syndrome. 61
31471277 2019
33
Posture commonly and considerably modifies stenosis of left common iliac and left renal veins in women diagnosed with pelvic venous disorder. 61
31444091 2019
34
Surgical aspects of venous pelvic pain treatment. 61
31188059 2019
35
Calcitonin Gene-Related Peptide and Substance P As Predictors of Venous Pelvic Pain. 61
31993239 2019
36
The Effect of a Subsequent Pregnancy After Ovarian Vein Embolization in Patients with Infertility Caused by Pelvic Congestion Syndrome. 61
30660471 2019
37
Vascular Disease Patient Information Page: Pelvic venous reflux (pelvic congestion syndrome). 61
31441390 2019
38
May-Thurner syndrome presenting as pelvic congestion syndrome and vulvar varicosities in a nonpregnant adolescent. 61
31304434 2019
39
Diagnosis and treatment of pelvic congestion syndrome: UIP consensus document. 61
31345010 2019
40
One-Year Results of Iliocaval Stenting. 61
30826434 2019
41
Superficial Thrombosis of Pelvic Congestion Syndrome Mimicking Pelvic Abscess. 61
31404359 2019
42
Ultrasound of Pelvic Pain in the Nonpregnant Woman. 61
30928080 2019
43
Pelvic congestion syndrome - treatment with pelvic varicose veins embolization. 61
31066803 2019
44
[Varicoceles, pelvic varices and pelvic congestion syndrome: Interventional radiology in diagnosis and treatment]. 61
31097262 2019
45
Variant Drainage of Left Internal Iliac Vein to Right Common Iliac Vein Potentiating Pelvic Congestion Syndrome. 61
30910190 2019
46
An unusual cause of postmenopausal vaginal haemorrhage: a case report. 61
30732650 2019
47
Is the endovascular embolization of tributaries of the internal iliac veins essential in the treatment of isolated pelvic-perineal reflux? 61
29985674 2019
48
[Embolization of insufficient pelvic veins for pelvic congestion syndrome. Analysis of 17 cases]. 61
30848763 2019
49
Regarding "Correlation between pelvic congestion syndrome and body mass index". 61
30554744 2019
50
Pelvic congestion syndrome due to agenesis of the infrarenal inferior vena cava. 61
30305863 2019

Variations for Taylor's Syndrome

Expression for Taylor's Syndrome

Search GEO for disease gene expression data for Taylor's Syndrome.

Pathways for Taylor's Syndrome

GO Terms for Taylor's Syndrome

Biological processes related to Taylor's Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron apoptotic process GO:0043524 9.4 SYNGAP1 RASA1
2 neuropeptide signaling pathway GO:0007218 9.37 TAC1 CALCA
3 regulation of GTPase activity GO:0043087 9.32 SYNGAP1 RASA1
4 regulation of blood pressure GO:0008217 9.26 TAC1 CALCA
5 cellular response to nerve growth factor stimulus GO:1990090 9.16 TAC1 CALCA
6 negative regulation of Ras protein signal transduction GO:0046580 8.96 SYNGAP1 RASA1
7 response to pain GO:0048265 8.62 TAC1 CALCA

Sources for Taylor's Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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