MCID: TTH030
MIFTS: 24

Teeth, Supernumerary

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Teeth, Supernumerary

MalaCards integrated aliases for Teeth, Supernumerary:

Name: Teeth, Supernumerary 57
Supernumerary Teeth 55

Characteristics:

OMIM:

57
Inheritance:
autosomal dominant


HPO:

32
teeth, supernumerary:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 57 187100
MedGen 42 C0040457
ICD10 33 K00.1

Summaries for Teeth, Supernumerary

MalaCards based summary : Teeth, Supernumerary, also known as supernumerary teeth, is related to cleidocranial dysplasia and craniosynostosis and dental anomalies. An important gene associated with Teeth, Supernumerary is RUNX2 (Runt Related Transcription Factor 2). Related phenotypes are increased number of teeth and mesiodens

Description from OMIM: 187100

Related Diseases for Teeth, Supernumerary

Diseases related to Teeth, Supernumerary via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 cleidocranial dysplasia 11.3
2 craniosynostosis and dental anomalies 11.1
3 odontoma 10.1
4 taurodontism 10.0
5 aggressive periodontitis 10.0
6 periodontitis 10.0
7 achondroplasia 9.8
8 sotos syndrome 1 9.8
9 crouzon syndrome 9.8
10 zimmermann-laband syndrome 1 9.8
11 hallermann-streiff syndrome 9.8
12 craniosynostosis 9.8
13 ehlers-danlos syndrome 9.8
14 anodontia 9.8
15 periodontosis 9.8
16 zimmermann-laband syndrome 9.8
17 hypophosphatasia 9.2 DSPP RUNX2
18 root resorption 9.0 DSPP RUNX2

Graphical network of the top 20 diseases related to Teeth, Supernumerary:



Diseases related to Teeth, Supernumerary

Symptoms & Phenotypes for Teeth, Supernumerary

Symptoms via clinical synopsis from OMIM:

57
Teeth:
mesiodens
supernumerary teeth


Clinical features from OMIM:

187100

Human phenotypes related to Teeth, Supernumerary:

32
# Description HPO Frequency HPO Source Accession
1 increased number of teeth 32 HP:0011069
2 mesiodens 32 HP:0011067

Drugs & Therapeutics for Teeth, Supernumerary

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Exact Localisation of Impacted and Supernumerary Teeth by Cone Beam Computer Tomography Completed NCT01002131

Search NIH Clinical Center for Teeth, Supernumerary

Genetic Tests for Teeth, Supernumerary

Anatomical Context for Teeth, Supernumerary

Publications for Teeth, Supernumerary

Articles related to Teeth, Supernumerary:

(show all 50)
# Title Authors Year
1
Multiple unerupted and supernumerary teeth in a patient with cleidocranial dysplasia. ( 29487646 )
2018
2
Removal of Supernumerary Teeth Utilizing a Computer-Aided Design/Computer-Aided Manufacturing Surgical Guide. ( 27914227 )
2017
3
A novel mutation of adenomatous polyposis coli (APC) gene results in the formation of supernumerary teeth. ( 28782241 )
2017
4
Navigation-Guided Extraction of Impacted Supernumerary Teeth: A Case Report. ( 28279686 )
2017
5
Achondroplasia with multiple supplemental supernumerary teeth and multiple talon cusps: A rare case report. ( 28702065 )
2017
6
Crouzon syndrome with multiple supernumerary teeth. ( 28091449 )
2017
7
Characteristics of Supernumerary Teeth in Nonsyndromic Population in an Urban Dental School Setting. ( 29127774 )
2017
8
Bilateral molariform supernumerary teeth in the anterior maxilla: a report of two cases. ( 28955588 )
2017
9
[Supernumerary teeth in the maxilla and mandible-an interdisciplinary challenge. Part 2: diagnostic pathways and current therapeutic concepts]. ( 27023707 )
2016
10
Genetic background of supernumerary teeth. ( 25713500 )
2015
11
Supernumerary teeth: an investigating tool in forensic crime investigation. ( 26028905 )
2015
12
Supernumerary teeth in Nepalese children. ( 25506609 )
2014
13
Under your nose: a rare finding during dissection provides insights into maxillary supernumerary teeth. ( 24861905 )
2014
14
Identification of supernumerary teeth in 2D and 3D: review of literature and a proposal. ( 23314464 )
2013
15
RUNX2 gene status in a cleidocranial dysplasia patient without supernumerary teeth. ( 23188595 )
2013
16
Surgical management of impacted incisors in associate with supernumerary teeth: a combine case report of spontaneous eruption and orthodontic extrusion. ( 23514686 )
2012
17
An unusual presentation of generalized aggressive periodontitis with multiple impacted supernumerary teeth. ( 22904664 )
2012
18
Management of Delayed Eruption of Permanent Maxillary Incisor associated with the Presence of Supernumerary Teeth: A Case Report. ( 27678238 )
2011
19
PAX6 polymorphisms in 20 Chinese children with supernumerary teeth in the maxillary incisor area. ( 21348901 )
2011
20
Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. ( 21741611 )
2011
21
Taurodontism in children with hypodontia and supernumerary teeth: a case control study. ( 20483017 )
2010
22
Multiple supernumerary teeth and odontoma in the maxilla: A case report. ( 22114378 )
2010
23
Supernumerary teeth in a Turkish population. ( 19962608 )
2009
24
Supernumerary teeth and dental management in Sotos syndrome. ( 19941770 )
2009
25
Impacted maxillary central incisor, canine, and second molar with 2 supernumerary teeth and an odontoma. ( 19268839 )
2009
26
Characteristics, clinical features and treatment of supernumerary teeth. ( 19476099 )
2009
27
Odontogenic keratocyst and multiple supernumerary teeth in a patient with Ehlers-Danlos syndrome--a case report and review of the literature. ( 18618041 )
2008
28
Tricho-rhino-phalangeal syndrome with supernumerary teeth. ( 18946009 )
2008
29
Familial occurrence of nonsyndromal multiple supernumerary teeth. A rare condition. ( 17029528 )
2006
30
Characteristics and prevalence of non-syndrome multiple supernumerary teeth: a retrospective study. ( 16618853 )
2006
31
Hallermann-Streiff syndrome: those are not supernumerary teeth. ( 16615982 )
2006
32
Multiple and relapsing supernumerary teeth associated to dens invaginatus. Review of the literature and case report. ( 15985986 )
2005
33
Tuberculate and odontoma type supernumerary teeth. ( 16327561 )
2005
34
Aggressive periodontitis with supernumerary teeth: a retrospective study. ( 15633320 )
2004
35
A case of Zimmermann-Laband syndrome with supernumerary teeth. ( 14514238 )
2003
36
A rare non-syndrome case of concomitant multiple supernumerary teeth and partial anodontia. ( 11314218 )
2001
37
A retrospective study of unerupted maxillary incisors associated with supernumerary teeth. ( 10783451 )
2000
38
Multiple supernumerary teeth: literature review and case report. ( 10686902 )
1999
39
Taurodontism in association with supernumerary teeth. ( 10204458 )
1999
40
A rare case of hereditary multiple impacted normal and supernumerary teeth. ( 10023236 )
1998
41
Frequency of supernumerary teeth in a dolichocephalic canine breed, the greyhound. ( 9442236 )
1998
42
Use of selectively colored stereolithography for diagnosis of impacted supernumerary teeth for a patient with cleidocranial dysplasia. ( 9743649 )
1998
43
Multiple supernumerary teeth in association with cleidocranial dysplasia. ( 9161213 )
1996
44
Late development of supernumerary teeth: a report of two cases. ( 8142324 )
1993
45
Assessment of 100 children in Jerusalem with supernumerary teeth in the premaxillary region. ( 1537940 )
1992
46
Anterior maxillary supernumerary teeth: a clinical and radiographic study. ( 1627067 )
1992
47
[Supernumerary teeth. A case report]. ( 2615736 )
1989
48
Progressive development of supernumerary teeth in cleidocranial dysplasia. ( 2775702 )
1989
49
Unerupted maxillary anterior supernumerary teeth: report of 204 cases. ( 6590583 )
1984
50
A comparison of identical twins in relation to three dental anomalies: multiple supernumerary teeth, juvenile periodontosis, and zero caries incidence. ( 6946362 )
1981

Variations for Teeth, Supernumerary

Expression for Teeth, Supernumerary

Search GEO for disease gene expression data for Teeth, Supernumerary.

Pathways for Teeth, Supernumerary

GO Terms for Teeth, Supernumerary

Biological processes related to Teeth, Supernumerary according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 skeletal system development GO:0001501 8.96 DSPP RUNX2
2 ossification GO:0001503 8.62 DSPP RUNX2

Sources for Teeth, Supernumerary

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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