MCID: TLN002
MIFTS: 21

Telangiectatic Osteogenic Sarcoma

Categories: Cancer diseases, Bone diseases

Aliases & Classifications for Telangiectatic Osteogenic Sarcoma

MalaCards integrated aliases for Telangiectatic Osteogenic Sarcoma:

Name: Telangiectatic Osteogenic Sarcoma 12 15
Telangiectatic Osteosarcoma 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:6951
NCIt 50 C3902
SNOMED-CT 68 78453009
UMLS 73 C0259782

Summaries for Telangiectatic Osteogenic Sarcoma

MalaCards based summary : Telangiectatic Osteogenic Sarcoma, also known as telangiectatic osteosarcoma, is related to osteogenic sarcoma and sarcoma, and has symptoms including pain An important gene associated with Telangiectatic Osteogenic Sarcoma is CYP4V2 (Cytochrome P450 Family 4 Subfamily V Member 2). The drugs Cyproheptadine and Histamine have been mentioned in the context of this disorder. Affiliated tissues include bone.

Related Diseases for Telangiectatic Osteogenic Sarcoma

Diseases related to Telangiectatic Osteogenic Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 osteogenic sarcoma 10.5
2 sarcoma 10.5
3 retinoblastoma 9.9
4 aneurysmal bone cysts 9.9

Symptoms & Phenotypes for Telangiectatic Osteogenic Sarcoma

UMLS symptoms related to Telangiectatic Osteogenic Sarcoma:


pain

Drugs & Therapeutics for Telangiectatic Osteogenic Sarcoma

Drugs for Telangiectatic Osteogenic Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyproheptadine Approved Phase 3 129-03-3 2913
2
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
3
Histamine Phosphate Phase 3 51-74-1 65513
4 Serotonin Agents Phase 3
5 Serotonin Antagonists Phase 3
6 Gastrointestinal Agents Phase 3
7 Neurotransmitter Agents Phase 3
8 Histamine Antagonists Phase 3
9 Histamine H1 Antagonists Phase 3
10 Dermatologic Agents Phase 3
11 Anti-Allergic Agents Phase 3
12 Antipruritics Phase 3
13
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
14
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
15 Angiogenesis Inhibitors Phase 2
16 Angiogenesis Modulating Agents Phase 2
17 Immunosuppressive Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
2 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2 sunitinib malate

Search NIH Clinical Center for Telangiectatic Osteogenic Sarcoma

Genetic Tests for Telangiectatic Osteogenic Sarcoma

Anatomical Context for Telangiectatic Osteogenic Sarcoma

MalaCards organs/tissues related to Telangiectatic Osteogenic Sarcoma:

41
Bone

Publications for Telangiectatic Osteogenic Sarcoma

Articles related to Telangiectatic Osteogenic Sarcoma:

# Title Authors Year
1
Telangiectatic osteogenic sarcoma: an unusual presentation. ( 1400148 )
1992
2
Telangiectatic osteogenic sarcoma of the extremities. Results in 17 patients treated with neoadjuvant chemotherapy. ( 1884565 )
1991
3
Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for telangiectatic osteogenic sarcoma of the extremities. ( 2477510 )
1989
4
Telangiectatic osteogenic sarcoma. Improved survival with combination chemotherapy. ( 2424660 )
1986
5
Telangiectatic osteogenic sarcoma: a clinicopathologic study of 124 patients. ( 6950802 )
1982
6
Telangiectatic osteogenic sarcoma. ( 1069603 )
1976
7
Telangiectatic osteogenic sarcoma. A review of twenty-eight cases. ( 4529332 )
1974

Variations for Telangiectatic Osteogenic Sarcoma

Expression for Telangiectatic Osteogenic Sarcoma

Search GEO for disease gene expression data for Telangiectatic Osteogenic Sarcoma.

Pathways for Telangiectatic Osteogenic Sarcoma

GO Terms for Telangiectatic Osteogenic Sarcoma

Biological processes related to Telangiectatic Osteogenic Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 8.62 CYCS CYP4V2

Molecular functions related to Telangiectatic Osteogenic Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heme binding GO:0020037 8.62 CYCS CYP4V2

Sources for Telangiectatic Osteogenic Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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