MCID: TLG001
MIFTS: 30

Telogen Effluvium

Categories: Skin diseases

Aliases & Classifications for Telogen Effluvium

MalaCards integrated aliases for Telogen Effluvium:

Name: Telogen Effluvium 12 15 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:1943
ICD9CM 34 704.02
NCIt 49 C112200
SNOMED-CT 67 39479004
ICD10 32 L65.0
UMLS 71 C0263518

Summaries for Telogen Effluvium

MalaCards based summary : Telogen Effluvium is related to alopecia and diffuse alopecia areata. An important gene associated with Telogen Effluvium is SRD5A2 (Steroid 5 Alpha-Reductase 2). The drugs Adjuvants, Immunologic and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and testes, and related phenotype is integument.

Wikipedia : 74 Telogen effluvium is a scalp disorder characterized by the thinning or shedding of hair resulting from... more...

Related Diseases for Telogen Effluvium

Diseases related to Telogen Effluvium via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 alopecia 31.2 VDR SRD5A2 HR EDA2R
2 diffuse alopecia areata 31.2 SLITRK1 EDA2R
3 androgenic alopecia 30.6 SRD5A2 LPP HR FGF5 EDA2R
4 loose anagen hair syndrome 30.3 SLITRK1 DLGAP3
5 hypotrichosis 29.9 LPP HR CDH3
6 alopecia, androgenetic, 1 10.9
7 alopecia areata 10.8
8 iron metabolism disease 10.5
9 dermatitis 10.4
10 contact dermatitis 10.4
11 allergic contact dermatitis 10.4
12 facial hypertrichosis 10.3
13 polyposis, skin pigmentation, alopecia, and fingernail changes 10.3
14 immune deficiency disease 10.3
15 myeloma, multiple 10.3
16 taqi polymorphism 10.3
17 inflammatory bowel disease 10.3
18 biotin deficiency 10.3
19 covid-19 10.3
20 social phobia 10.3
21 personality disorder 10.3
22 ischemia 10.3
23 skin disease 10.3
24 hypertrichosis 10.3
25 pustulosis of palm and sole 10.3
26 plasma cell neoplasm 10.3
27 thyroiditis 10.3
28 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.3
29 crohn's disease 10.3
30 psoriasis 10.3
31 amyloidosis 10.3
32 eosinophilia-myalgia syndrome 10.3
33 hypereosinophilic syndrome 10.3
34 al amyloidosis 10.3
35 pustular psoriasis 10.3
36 paresthesia 10.3
37 spinal cord injury 10.3
38 neurodermatitis 10.2 TAC1 HR
39 follicular mucinosis 10.2 SLITRK1 LPP
40 tinea capitis 10.2 SLITRK1 LPP
41 alopecia universalis congenita 10.0 ULBP3 HR
42 kleptomania 10.0 SLITRK1 DLGAP3
43 chronic tic disorder 9.9 SLITRK1 DLGAP3
44 tic disorder 9.9 SLITRK1 DLGAP3
45 atrichia with papular lesions 9.9 VDR HR
46 body dysmorphic disorder 9.9 SLITRK1 DLGAP3
47 trichotillomania 9.8 SLITRK1 LPP DLGAP3
48 hair disease 9.6 VDR SRD5A2 LPP CDH3
49 impulse control disorder 9.5 SLITRK1 DLGAP3
50 acrodermatitis enteropathica, zinc-deficiency type 9.5 SLC39A2 SLC39A10

Graphical network of the top 20 diseases related to Telogen Effluvium:



Diseases related to Telogen Effluvium

Symptoms & Phenotypes for Telogen Effluvium

MGI Mouse Phenotypes related to Telogen Effluvium:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.23 CDH3 DLGAP3 FGF5 HR SLC39A10 SLC39A2

Drugs & Therapeutics for Telogen Effluvium

Drugs for Telogen Effluvium (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Adjuvants, Immunologic Phase 2
2 Anti-Infective Agents Phase 2
3 Protective Agents Phase 2
4 Radiation-Protective Agents Phase 2
5 Antiviral Agents Phase 2
6 Ammonium trichloro(dioxoethylene-O,O'-)tellurate Phase 2
7 Immunologic Factors Phase 2
8
Vitamin D Approved, Nutraceutical, Vet_approved 1406-16-2
9 Trace Elements
10 Vitamins
11 Nutrients
12 Micronutrients
13 Calciferol

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Clinical Trial, Placebo Controlled and Active Comparator, to Evaluate Efficacy and Safety of Neosil in Chronic Effluvium Completed NCT03659201 Phase 4 Neosil complete;Pantogar;Neosil
2 Phase 2 Study of Topical AS101 for the Treatment of FAGA (Female Androgenetic Alopecia) in Menopause Women Unknown status NCT00418249 Phase 2 AS101
3 Demonstration of the Presence of Carbonyl Stress in the Hair Follicles of Women With Reactive Hair Loss Completed NCT03414476
4 Controlled, Randomized, Double Blind Study, for the Evaluation of Tolerance and Trichological Efficacy of a Food Supplement: Bioscalin® New Formulation Versus Reference Formulation Currently on the Market and Placebo Completed NCT03272750
5 Demonstration of the Presence of a Carbonyl Stress in the Hair Follicles of Postpartum Women Completed NCT04237402
6 Evaluating PAI-1 Expression in the Hair Follicles of Patients With Non-scarring Hair Loss. Enrolling by invitation NCT02548689
7 Role of Vitamin D in Androgenetic Alopecia Not yet recruiting NCT03154528

Search NIH Clinical Center for Telogen Effluvium

Genetic Tests for Telogen Effluvium

Anatomical Context for Telogen Effluvium

MalaCards organs/tissues related to Telogen Effluvium:

40
Skin, Thyroid, Testes, Spinal Cord

Publications for Telogen Effluvium

Articles related to Telogen Effluvium:

(show top 50) (show all 304)
# Title Authors PMID Year
1
Study of serum vitamin D levels in men with premature androgenetic alopecia. 61
32516435 2020
2
Low-dose oral minoxidil as treatment for non-scarring alopecia: a systematic review. 61
32516434 2020
3
Efficacy and safety of a new formulation kit (shampoo + lotion) containing anti-inflammatory and antioxidant agents to treat hair loss. 61
32134172 2020
4
The use of phosphodiesterase inhibitors for the treatment of alopecia. 61
30935254 2020
5
Management of telogen effluvium during the COVID-19 emergency: Psychological implications. 61
32445237 2020
6
Ischemia-modified albumin as a possible marker of oxidative stress in patients with telogen effluvium. 61
32482549 2020
7
Oral isotretinoin combined with topical clobetasol 0.05% and tacrolimus 0.1% for the treatment of frontal fibrosing alopecia: a randomized controlled trial. 61
32238014 2020
8
Biotin Deficiency in Telogen Effluvium: Fact or Fiction? 61
32308796 2020
9
Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time. 61
30307062 2020
10
Preliminary results of the use of scalp microneedling in different types of alopecia. 61
31254437 2020
11
The Role of Diet as an Adjuvant Treatment in Scarring and Nonscarring Alopecia. 61
32258051 2020
12
Relationship between helicobacter pylori infection and pityriasis versicolor: Can helicobacter pylori infection be a new etiologic factor for pityriasis versicolor? 61
32151117 2020
13
"Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women". 61
31135099 2020
14
Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern Hair Loss and Telogen Effluvium. 61
32425997 2020
15
Risk Analysis of Lurasidone in Patients with Schizophrenia and Bipolar Depression. 61
32124704 2020
16
Increased Preauricular Wrinkles in Frontal Fibrosing Alopecia Compared to Age-Matched Controls: A Prospective Study of 64 Patients. 61
32021855 2020
17
Types and Treatment of Hair Loss in Men and Women. 61
32102074 2020
18
Dilation of Multiple Eccrine Ducts as a Highly Specific Marker for Cicatricial Alopecia. 61
31764231 2019
19
Alopecia in Cronkhite-Canada syndrome: Is it truly telogen effluvium? 61
31056741 2019
20
Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study. 61
31559256 2019
21
Overnight Alopecia: A Subtype of Acute Diffuse and Total Alopecia? 61
31523109 2019
22
A Clinico-Epidemiological Study of Scalp Hair Loss in Children (0-18 Years) in Kota Region, South-East Rajasthan. 61
31516137 2019
23
Focal atrichia: A diagnostic clue in female pattern hair loss. 61
29017840 2019
24
Treatment of telogen effluvium using a dietary supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera: Results of an observational study. 61
30693615 2019
25
New pattern hair loss in young Turkish women; What's wrong in their daily life? 61
30614076 2019
26
Expert consensus on the management of Telogen Effluvium in India. 61
31360038 2019
27
Off-Label Use of Topical Minoxidil in Alopecia: A Review. 61
30604379 2019
28
Effects of isotretinoin on the hair cycle. 61
30350907 2019
29
HrQoL in hair loss-affected patients with alopecia areata, androgenetic alopecia and telogen effluvium: the role of personality traits and psychosocial anxiety. 61
30394586 2019
30
The role of photobiomodulation when associated with microneedling in female pattern hair loss: A randomized, double blind, parallel group, three arm, clinical study protocol. 61
30896659 2019
31
Beau lines and telogen effluvium following aluminium phosphide poisoning. 61
30845132 2019
32
Postfebrile telogen effluvium: hair fall after Rickettsia conorii infection. 61
28704990 2019
33
NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. 61
29774652 2019
34
Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort. 61
30455235 2019
35
The influence of methotrexate on hair loss while using immunomodulatory doses. 61
30830893 2019
36
Research on the Balance of Thiol-Disulfide in Blood Serum in Women with Telogen Effluvium. 61
30820129 2019
37
Telogen effluvium x female pattern hair loss: is there correlation? 61
31644631 2019
38
Scalp biopsy identifies systemic amyloidosis presenting as isolated telogen effluvium: A case report. 61
31105951 2019
39
Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study. 61
31632122 2019
40
Telogen effluvium: a comprehensive review. 61
31686886 2019
41
Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. 61
30466067 2018
42
Telogen Effluvium With Dysesthesia (TED) Has Lower B12 Levels and May Respond to B12 Supplementation 61
30500148 2018
43
White and yellow dots as new trichoscopic signs of severe female androgenetic alopecia in dark skin phototypes. 61
30043983 2018
44
Common causes of paediatric alopecia 61
31195774 2018
45
Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus. 61
29948959 2018
46
Color-transition sign: A useful trichoscopic finding for differentiating alopecia areata incognita from telogen effluvium. 61
29512186 2018
47
Naked Hair Shafts as a Marker of Cicatricial Alopecia. 61
29293128 2018
48
A proprietary herbal extract against hair loss in androgenetic alopecia and telogen effluvium: a placebo-controlled, single-blind, clinical-instrumental study. 61
29945259 2018
49
Horizontal and vertical sections of scalp biopsy specimens from dermatomyositis patients with scalp involvement. 61
29409918 2018
50
New multi-targeting strategy in hair growth promotion: in vitro and in vivo studies. 61
29766701 2018

Variations for Telogen Effluvium

Expression for Telogen Effluvium

Search GEO for disease gene expression data for Telogen Effluvium.

Pathways for Telogen Effluvium

GO Terms for Telogen Effluvium

Cellular components related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.32 ULBP3 TAC1 SLITRK1 SLC39A2 SLC39A10 OR2AT4

Biological processes related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.33 TAC1 SRD5A2 FGF5
2 metal ion transport GO:0030001 8.96 SLC39A2 SLC39A10
3 zinc ion transport GO:0006829 8.62 SLC39A2 SLC39A10

Molecular functions related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zinc ion transmembrane transporter activity GO:0005385 8.96 SLC39A2 SLC39A10
2 metal ion transmembrane transporter activity GO:0046873 8.62 SLC39A2 SLC39A10

Sources for Telogen Effluvium

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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