MCID: TLG001
MIFTS: 29

Telogen Effluvium

Categories: Skin diseases

Aliases & Classifications for Telogen Effluvium

MalaCards integrated aliases for Telogen Effluvium:

Name: Telogen Effluvium 12 15 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:1943
ICD9CM 34 704.02
NCIt 49 C112200
SNOMED-CT 67 39479004
ICD10 32 L65.0
UMLS 71 C0263518

Summaries for Telogen Effluvium

MalaCards based summary : Telogen Effluvium is related to alopecia and diffuse alopecia areata. An important gene associated with Telogen Effluvium is ANTXR2 (ANTXR Cell Adhesion Molecule 2). The drugs Folic acid and Thiamine have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and testes.

Wikipedia : 74 Telogen effluvium is a scalp disorder characterized by the thinning or shedding of hair resulting from... more...

Related Diseases for Telogen Effluvium

Diseases related to Telogen Effluvium via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 alopecia 31.3 VDR SRD5A2 EDA2R
2 diffuse alopecia areata 31.2 SLITRK1 EDA2R
3 androgenic alopecia 31.0 SRD5A2 LPP EDA2R ANTXR2
4 hypotrichosis 29.8 VDR LPP CDH3 ANTXR2
5 alopecia, androgenetic, 1 10.9
6 alopecia areata 10.8
7 iron metabolism disease 10.5
8 dermatitis 10.4
9 contact dermatitis 10.4
10 allergic contact dermatitis 10.4
11 facial hypertrichosis 10.3
12 polyposis, skin pigmentation, alopecia, and fingernail changes 10.3
13 immune deficiency disease 10.3
14 myeloma, multiple 10.3
15 taqi polymorphism 10.3
16 loose anagen hair syndrome 10.3
17 inflammatory bowel disease 10.3
18 social phobia 10.3
19 personality disorder 10.3
20 skin disease 10.3
21 hypertrichosis 10.3
22 pustulosis of palm and sole 10.3
23 thyroiditis 10.3
24 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.3
25 crohn's disease 10.3
26 psoriasis 10.3
27 amyloidosis 10.3
28 eosinophilia-myalgia syndrome 10.3
29 hypereosinophilic syndrome 10.3
30 al amyloidosis 10.3
31 pustular psoriasis 10.3
32 paresthesia 10.3
33 spinal cord injury 10.3
34 trigeminal nerve disease 10.3 TAC1 ANTXR2
35 arachnoiditis 10.2 TAC1 FTH1
36 follicular mucinosis 10.2 SLITRK1 LPP
37 tinea capitis 10.2 SLITRK1 LPP
38 polyradiculopathy 10.2 TAC1 FTH1
39 trigeminal neuralgia 10.2 TAC1 ANTXR2
40 kleptomania 10.1 SLITRK1 DLGAP3
41 chronic tic disorder 10.0 SLITRK1 DLGAP3
42 tic disorder 10.0 SLITRK1 DLGAP3
43 body dysmorphic disorder 10.0 SLITRK1 DLGAP3
44 impulse control disorder 9.9 SLITRK1 DLGAP3
45 multidrug-resistant tuberculosis 9.9 VDR ANTXR2
46 trichotillomania 9.8 SLITRK1 DLGAP3
47 bone deterioration disease 9.7 VDR FTH1
48 hair disease 9.6 VDR LPP CDH3 ANTXR2

Graphical network of the top 20 diseases related to Telogen Effluvium:



Diseases related to Telogen Effluvium

Symptoms & Phenotypes for Telogen Effluvium

Drugs & Therapeutics for Telogen Effluvium

Drugs for Telogen Effluvium (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
2
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 4 59-43-8, 70-16-6 1130
3
Pantothenic acid Approved, Nutraceutical, Vet_approved Phase 4 79-83-4 6613
4 Vitamin B Complex Phase 4
5 Vitamin B9 Phase 4
6 Folate Phase 4
7 Thiamin Phase 4
8 Ammonium trichloro(dioxoethylene-O,O'-)tellurate Phase 2
9 Immunologic Factors Phase 2
10 Protective Agents Phase 2
11 Anti-Infective Agents Phase 2
12 Radiation-Protective Agents Phase 2
13 Adjuvants, Immunologic Phase 2
14 Antiviral Agents Phase 2
15
Ergocalciferol Approved, Nutraceutical 50-14-6 5280793
16
Vitamin D Approved, Nutraceutical, Vet_approved 1406-16-2
17
Calcium Approved, Nutraceutical 7440-70-2 271
18 Plasminogen Activator Inhibitor 1
19 Trace Elements
20 Vitamins
21 Micronutrients
22 Nutrients
23 Ergocalciferols
24 Vitamin D2
25 Calciferol
26 Calcium, Dietary
27 Hormones

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Clinical Trial, Placebo Controlled and Active Comparator, to Evaluate Efficacy and Safety of Neosil in Chronic Effluvium Recruiting NCT03659201 Phase 4 Neosil complete;Pantogar;Neosil
2 Phase 2 Study of Topical AS101 for the Treatment of FAGA (Female Androgenetic Alopecia) in Menopause Women Unknown status NCT00418249 Phase 2 AS101
3 Controlled, Randomized, Double Blind Study, for the Evaluation of Tolerance and Trichological Efficacy of a Food Supplement: Bioscalin® New Formulation Versus Reference Formulation Currently on the Market and Placebo Completed NCT03272750
4 Evaluating PAI-1 Expression in the Hair Follicles of Patients With Non-scarring Hair Loss. Enrolling by invitation NCT02548689
5 Demonstration of the Presence of Carbonyl Stress in the Hair Follicles of Women With Reactive Hair Loss Not yet recruiting NCT03414476
6 Role of Vitamin D in Androgenetic Alopecia Not yet recruiting NCT03154528

Search NIH Clinical Center for Telogen Effluvium

Genetic Tests for Telogen Effluvium

Anatomical Context for Telogen Effluvium

MalaCards organs/tissues related to Telogen Effluvium:

40
Skin, Thyroid, Testes, Spinal Cord

Publications for Telogen Effluvium

Articles related to Telogen Effluvium:

(show top 50) (show all 291)
# Title Authors PMID Year
1
Dilation of Multiple Eccrine Ducts as a Highly Specific Marker for Cicatricial Alopecia. 61
31764231 2019
2
Alopecia in Cronkhite-Canada syndrome: Is it truly telogen effluvium? 61
31056741 2019
3
Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study. 61
31559256 2019
4
A Clinico-Epidemiological Study of Scalp Hair Loss in Children (0-18 Years) in Kota Region, South-East Rajasthan. 61
31516137 2019
5
Overnight Alopecia: A Subtype of Acute Diffuse and Total Alopecia? 61
31523109 2019
6
Focal atrichia: A diagnostic clue in female pattern hair loss. 61
29017840 2019
7
Preliminary results of the use of scalp microneedling in different types of alopecia. 61
31254437 2019
8
New pattern hair loss in young Turkish women; What's wrong in their daily life? 61
30614076 2019
9
Expert consensus on the management of Telogen Effluvium in India. 61
31360038 2019
10
"Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women". 61
31135099 2019
11
Treatment of telogen effluvium using a dietary supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera: Results of an observational study. 61
30693615 2019
12
The use of phosphodiesterase inhibitors for the treatment of alopecia. 61
30935254 2019
13
Off-Label Use of Topical Minoxidil in Alopecia: A Review. 61
30604379 2019
14
Effects of isotretinoin on the hair cycle. 61
30350907 2019
15
HrQoL in hair loss-affected patients with alopecia areata, androgenetic alopecia and telogen effluvium: the role of personality traits and psychosocial anxiety. 61
30394586 2019
16
The role of photobiomodulation when associated with microneedling in female pattern hair loss: A randomized, double blind, parallel group, three arm, clinical study protocol. 61
30896659 2019
17
Beau lines and telogen effluvium following aluminium phosphide poisoning. 61
30845132 2019
18
Postfebrile telogen effluvium: hair fall after Rickettsia conorii infection. 61
28704990 2019
19
NonScarring Diffuse Hair Loss in Women: a Clinico-Etiological Study from tertiary care center in North-West India. 61
29774652 2019
20
Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort. 61
30455235 2019
21
The influence of methotrexate on hair loss while using immunomodulatory doses. 61
30830893 2019
22
Telogen effluvium x female pattern hair loss: is there correlation? 61
31644631 2019
23
Research on the Balance of Thiol-Disulfide in Blood Serum in Women with Telogen Effluvium. 61
30820129 2019
24
Scalp biopsy identifies systemic amyloidosis presenting as isolated telogen effluvium: A case report. 61
31105951 2019
25
Vitamin D Receptor Gene Polymorphism In Chronic Telogen Effluvium; A Case-Control Study. 61
31632122 2019
26
Telogen effluvium: a comprehensive review. 61
31686886 2019
27
Cystine-thiamin-containing hair-growth formulation modulates the response to UV radiation in an in vitro model for growth-limiting conditions of human keratinocytes. 61
30466067 2018
28
Telogen Effluvium With Dysesthesia (TED) Has Lower B12 Levels and May Respond to B12 Supplementation 61
30500148 2018
29
Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time. 61
30307062 2018
30
White and yellow dots as new trichoscopic signs of severe female androgenetic alopecia in dark skin phototypes. 61
30043983 2018
31
Common causes of paediatric alopecia 61
31195774 2018
32
Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus. 61
29948959 2018
33
Color-transition sign: A useful trichoscopic finding for differentiating alopecia areata incognita from telogen effluvium. 61
29512186 2018
34
Naked Hair Shafts as a Marker of Cicatricial Alopecia. 61
29293128 2018
35
A proprietary herbal extract against hair loss in androgenetic alopecia and telogen effluvium: a placebo-controlled, single-blind, clinical-instrumental study. 61
29945259 2018
36
New multi-targeting strategy in hair growth promotion: in vitro and in vivo studies. 61
29766701 2018
37
Horizontal and vertical sections of scalp biopsy specimens from dermatomyositis patients with scalp involvement. 61
29409918 2018
38
Assessment of Heavy Metal and Trace Element Levels in Patients with Telogen Effluvium. 61
29937562 2018
39
Localized Telogen Effluvium Following Hair Transplantation. 61
29606820 2018
40
Elastic Staining in Differentiating Between Follicular Streamers and Follicular Scars in Horizontal Scalp Biopsy Sections. 61
28816743 2018
41
Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia. 61
30302033 2018
42
Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells. 61
30186771 2018
43
Non-scarring Alopecias in Iranian Patients: A Histopathological Study With Hair Counts. 61
30636954 2018
44
Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. 61
30237729 2018
45
Telogen Effluvium: Is There a Need for a New Classification? A Reply. 61
29457010 2018
46
Alopecias in lupus erythematosus. 61
30397497 2018
47
The Role of Vitamin D in Non-Scarring Alopecia. 61
29215595 2017
48
Physiologic changes of pregnancy: A review of the literature. 61
29234716 2017
49
Exogen Hairs in Women with and without Hair Loss. 61
29177147 2017
50
Three Cases of Hair Loss Analyzed by the Point of View of the Analytical Psychology. 61
29118523 2017

Variations for Telogen Effluvium

Expression for Telogen Effluvium

Search GEO for disease gene expression data for Telogen Effluvium.

Pathways for Telogen Effluvium

GO Terms for Telogen Effluvium

Cellular components related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.73 ULBP3 SRD5A2 SLITRK1 SLC39A10 OR2AT4 LPP
2 plasma membrane GO:0005886 9.36 ULBP3 TAC1 SLITRK1 SLC39A10 OR2AT4 LPP

Biological processes related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 natural killer cell mediated cytotoxicity GO:0042267 8.62 ULBP3 CLEC2A

Molecular functions related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor activity GO:0038023 8.8 VDR EDA2R ANTXR2

Sources for Telogen Effluvium

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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