MCID: TLG001
MIFTS: 31

Telogen Effluvium

Categories: Skin diseases

Aliases & Classifications for Telogen Effluvium

MalaCards integrated aliases for Telogen Effluvium:

Name: Telogen Effluvium 12 15 70 32

Classifications:



External Ids:

Disease Ontology 12 DOID:1943
ICD9CM 34 704.02
NCIt 50 C112200
SNOMED-CT 67 201147004
ICD10 32 L65.0
UMLS 70 C0263518

Summaries for Telogen Effluvium

MalaCards based summary : Telogen Effluvium is related to alopecia and androgenic alopecia. An important gene associated with Telogen Effluvium is OR2AT4 (Olfactory Receptor Family 2 Subfamily AT Member 4), and among its related pathways/superpathways are Calcium signaling pathway and Vemurafenib Pathway, Pharmacodynamics. The drug Nutrients has been mentioned in the context of this disorder. Affiliated tissues include skin, spinal cord and thyroid, and related phenotype is integument.

Wikipedia : 73 Telogen effluvium is a scalp disorder characterized by the thinning or shedding of hair resulting from... more...

Related Diseases for Telogen Effluvium

Diseases related to Telogen Effluvium via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 alopecia 31.5 SRD5A2 HR EDA2R
2 androgenic alopecia 30.3 SRD5A2 HR FGF7 FGF5 EDA2R
3 loose anagen hair syndrome 30.3 KRT75 DLGAP3
4 alopecia, androgenetic, 1 10.7
5 alopecia areata 10.6
6 diffuse alopecia areata 10.5
7 severe acute respiratory syndrome 10.4
8 iron metabolism disease 10.3
9 covid-19 10.3
10 dermatitis 10.3
11 contact dermatitis 10.3
12 allergic contact dermatitis 10.3
13 paresthesia 10.3
14 neurotrophic keratopathy 10.1 TACR1 TAC1
15 keratopathy 10.1 TACR1 TAC1
16 causalgia 10.1 TACR1 TAC1
17 alopecia universalis congenita 10.1 ULBP3 HR
18 facial hypertrichosis 10.1
19 polyposis, skin pigmentation, alopecia, and fingernail changes 10.1
20 immune deficiency disease 10.1
21 myeloma, multiple 10.1
22 taqi polymorphism 10.1
23 anxiety 10.1
24 biotin deficiency 10.1
25 social phobia 10.1
26 personality disorder 10.1
27 ischemia 10.1
28 skin disease 10.1
29 hypertrichosis 10.1
30 hair disease 10.1
31 pustulosis of palm and sole 10.1
32 hypotrichosis 10.1
33 plasma cell neoplasm 10.1
34 thyroiditis 10.1
35 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.1
36 crohn's disease 10.1
37 psoriasis 10.1
38 amyloidosis 10.1
39 eosinophilia-myalgia syndrome 10.1
40 hypereosinophilic syndrome 10.1
41 al amyloidosis 10.1
42 pustular psoriasis 10.1
43 spinal cord injury 10.1
44 epicondylitis 10.1 TACR1 TAC1
45 retinitis pigmentosa 67 10.1 TACR1 TAC1
46 trigeminal nerve disease 10.1 TACR1 TAC1
47 motion sickness 10.1 TACR1 TAC1
48 autonomic nervous system disease 10.0 TACR1 TAC1
49 chronic spontaneous urticaria 10.0 TACR1 TAC1
50 neurogenic bladder 10.0 TACR1 TAC1

Graphical network of the top 20 diseases related to Telogen Effluvium:



Diseases related to Telogen Effluvium

Symptoms & Phenotypes for Telogen Effluvium

MGI Mouse Phenotypes related to Telogen Effluvium:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.36 CDH3 DLGAP3 FGF5 FGF7 HR KRT75

Drugs & Therapeutics for Telogen Effluvium

Drugs for Telogen Effluvium (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Nutrients

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Clinical Trial, Placebo Controlled and Active Comparator, to Evaluate Efficacy and Safety of Neosil in Chronic Effluvium Completed NCT03659201 Phase 4 Neosil complete;Pantogar;Neosil
2 Hair Regrowth Efficacy of Multi-Molecular Targeting Treatment (ALRV5XR), a Randomized Controlled Clinical Trial in Women With Androgenetic Alopecia, Telogen Effluvium or Self Reported Thinning Hair: THE HAIR REBOOT TRIAL - WOMEN Completed NCT04450602
3 Hair Regrowth Efficacy of Multi-Molecular Targeting Treatment (ALRV5XR), a Randomized Controlled Clinical Trial in Men With Androgenetic Alopecia, Telogen Effluvium or Self Reported Thinning Hair: THE HAIR REBOOT TRIAL - MEN Completed NCT04450589
4 Randomized, Comparative Study to Assess the Effects of Cosmetic Lotion on Telogen Effluvium in Women Compared to a Control Group Completed NCT04652232
5 Demonstration of the Presence of a Carbonyl Stress in the Hair Follicles of Postpartum Women Completed NCT04237402
6 Controlled, Randomized, Double Blind Study, for the Evaluation of Tolerance and Trichological Efficacy of a Food Supplement: Bioscalin® New Formulation Versus Reference Formulation Currently on the Market and Placebo Completed NCT03272750

Search NIH Clinical Center for Telogen Effluvium

Genetic Tests for Telogen Effluvium

Anatomical Context for Telogen Effluvium

MalaCards organs/tissues related to Telogen Effluvium:

40
Skin, Spinal Cord, Thyroid

Publications for Telogen Effluvium

Articles related to Telogen Effluvium:

(show top 50) (show all 337)
# Title Authors PMID Year
1
Telomere Dynamics and Telomerase in the Biology of Hair Follicles and their Stem Cells as a Model for Aging Research. 61
33509633 2021
2
The role of sleep in telogen effluvium and trichodynia: A commentary in the context of the current pandemic. 61
33387387 2021
3
A surge in the incidence of telogen effluvium in minority predominant communities heavily impacted by COVID-19. 61
33310111 2021
4
SARS-CoV-2-induced telogen effluvium: a multicentric study. 61
33220124 2021
5
Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore® , improves telogen effluvium-associated parameters. 61
32645251 2021
6
Telogen effluvium in the new SARS-CoV-2 era. 61
33660272 2021
7
Telogen effluvium associated with COVID-19 infection. 61
33405302 2021
8
Oral minoxidil treatment for hair loss: A review of efficacy and safety. 61
32622136 2021
9
Trichobiolight: A new, effective protocol in the treatment of androgenetic alopecia and telogen effluvium. 61
33486860 2021
10
Review of oral minoxidil as treatment of hair disorders: in search of the perfect dose. 61
33660357 2021
11
Common causes of hair loss - clinical manifestations, trichoscopy and therapy. 61
33290611 2021
12
Results of low-level laser therapy in the treatment of hair growth: An Egyptian Experience. 61
33713522 2021
13
The Diagnostic Value of Serum Ferritin for Telogen Effluvium: A Cross-Sectional Comparative Study. 61
33603430 2021
14
Lichen-planopilaris-like scarring pattern in a patient with alopecia and pityriasis rubra pilaris. 61
32949041 2021
15
Acute Hepatitis and Pancytopenia in a Child With Chronic Abuse of Senna. 61
33552756 2021
16
Telogen effluvium: a sequela of COVID-19. 61
33226117 2021
17
Telogen effluvium related to post severe Sars-Cov-2 infection: Clinical aspects and our management experience. 61
33190397 2021
18
Laboratory Testing in Telogen Effluvium. 61
33400415 2021
19
Efficacy of Oral Vitamin D3 Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium). 61
33642467 2021
20
Telogen Effluvium - a review of the science and current obstacles. 61
33541773 2021
21
Chronic telogen effluvium in Egyptian children: Analysis of common risk factors. 61
32860324 2020
22
Evaluation of the effects of COVID-19 pandemic on hair diseases through a web-based questionnaire. 61
32594627 2020
23
Relative changes in the pattern of diseases presenting in dermatology outpatient clinic in the era of the COVID-19 pandemic. 61
32869938 2020
24
Prolonged and Late-Onset Symptoms of Coronavirus Disease 2019. 61
33230486 2020
25
Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. 61
33313047 2020
26
Types and Treatment of Hair Loss in Men and Women. 61
33259424 2020
27
Study of serum vitamin D levels in men with premature androgenetic alopecia. 61
32516435 2020
28
Topical L-thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy? 61
32682336 2020
29
Localized Telogen Effluvium of the Donor Area After Hair Transplant Surgery in 12 Patients. 61
32947302 2020
30
Acute telogen effluvium associated with SARS-CoV-2 infection. 61
33051638 2020
31
Low-dose oral minoxidil as treatment for non-scarring alopecia: a systematic review. 61
32516434 2020
32
Management of telogen effluvium during the COVID-19 emergency: Psychological implications. 61
32445237 2020
33
Ischemia-modified albumin as a possible marker of oxidative stress in patients with telogen effluvium. 61
32482549 2020
34
Relationship between helicobacter pylori infection and pityriasis versicolor: can helicobacter pylori infection be a new etiologic factor for pityriasis versicolor? 61
32151117 2020
35
Efficacy and safety of a new formulation kit (shampoo + lotion) containing anti-inflammatory and antioxidant agents to treat hair loss. 61
32134172 2020
36
The use of phosphodiesterase inhibitors for the treatment of alopecia. 61
30935254 2020
37
Pigtail Hair in Acute Telogen Effluvium - Lest We Forget! 61
32695715 2020
38
Telogen Effluvium: A Review of the Literature. 61
32607303 2020
39
Oral isotretinoin combined with topical clobetasol 0.05% and tacrolimus 0.1% for the treatment of frontal fibrosing alopecia: a randomized controlled trial. 61
32238014 2020
40
Biotin Deficiency in Telogen Effluvium: Fact or Fiction? 61
32308796 2020
41
Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time. 61
30307062 2020
42
Preliminary results of the use of scalp microneedling in different types of alopecia. 61
31254437 2020
43
The Role of Diet as an Adjuvant Treatment in Scarring and Nonscarring Alopecia. 61
32258051 2020
44
"Miliacin encapsulated by polar lipids stimulates cell proliferation in hair bulb and improves telogen effluvium in women". 61
31135099 2020
45
Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern Hair Loss and Telogen Effluvium. 61
32425997 2020
46
L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes. 61
32801826 2020
47
Increased Preauricular Wrinkles in Frontal Fibrosing Alopecia Compared to Age-Matched Controls: A Prospective Study of 64 Patients. 61
32021855 2020
48
Types and Treatment of Hair Loss in Men and Women. 61
32102074 2020
49
Risk Analysis of Lurasidone in Patients with Schizophrenia and Bipolar Depression. 61
32124704 2020
50
Dilation of Multiple Eccrine Ducts as a Highly Specific Marker for Cicatricial Alopecia. 61
31764231 2019

Variations for Telogen Effluvium

Expression for Telogen Effluvium

Search GEO for disease gene expression data for Telogen Effluvium.

Pathways for Telogen Effluvium

Pathways related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.71 TACR1 FGF7 FGF5
2 10.59 FGF7 FGF5
3 9.47 TACR1 TAC1

GO Terms for Telogen Effluvium

Biological processes related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.58 TAC1 SRD5A2 FGF5
2 metal ion transport GO:0030001 9.37 SLC39A2 SLC39A10
3 zinc ion transport GO:0006829 9.32 SLC39A2 SLC39A10
4 response to pain GO:0048265 9.26 TACR1 TAC1
5 positive regulation of keratinocyte proliferation GO:0010838 9.16 FGF7 CDH3
6 tachykinin receptor signaling pathway GO:0007217 8.96 TACR1 TAC1
7 detection of abiotic stimulus GO:0009582 8.62 TACR1 TAC1

Molecular functions related to Telogen Effluvium according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fibroblast growth factor receptor binding GO:0005104 9.16 FGF7 FGF5
2 zinc ion transmembrane transporter activity GO:0005385 8.96 SLC39A2 SLC39A10
3 metal ion transmembrane transporter activity GO:0046873 8.62 SLC39A2 SLC39A10

Sources for Telogen Effluvium

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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