MCID: TMP009
MIFTS: 9

Temperature-Sensitive Lethal Mutation

Aliases & Classifications for Temperature-Sensitive Lethal Mutation

MalaCards integrated aliases for Temperature-Sensitive Lethal Mutation:

Name: Temperature-Sensitive Lethal Mutation 57 54 70

External Ids:

OMIM® 57 187340
UMLS 70 C1861242

Summaries for Temperature-Sensitive Lethal Mutation

MalaCards based summary : Temperature-Sensitive Lethal Mutation An important gene associated with Temperature-Sensitive Lethal Mutation is CDC42 (Cell Division Cycle 42).

More information from OMIM: 187340

Related Diseases for Temperature-Sensitive Lethal Mutation

Symptoms & Phenotypes for Temperature-Sensitive Lethal Mutation

Clinical features from OMIM®:

187340 (Updated 20-May-2021)

Drugs & Therapeutics for Temperature-Sensitive Lethal Mutation

Search Clinical Trials , NIH Clinical Center for Temperature-Sensitive Lethal Mutation

Genetic Tests for Temperature-Sensitive Lethal Mutation

Anatomical Context for Temperature-Sensitive Lethal Mutation

Publications for Temperature-Sensitive Lethal Mutation

Articles related to Temperature-Sensitive Lethal Mutation:

(show all 22)
# Title Authors PMID Year
1
Rapid and precise engineering of the Caenorhabditis elegans genome with lethal mutation co-conversion and inactivation of NHEJ repair. 61
25491644 2015
2
Activation of the Escherichia coli β-barrel assembly machine (Bam) is required for essential components to interact properly with substrate. 61
22331884 2012
3
Wiser (tsl): a recessive X-linked temperature-sensitive lethal mutation that affects the wings and the eyes in Drosophila melanogaster. 61
18536996 2009
4
Loss of Hsp70 in Drosophila is pleiotropic, with effects on thermotolerance, recovery from heat shock and neurodegeneration. 61
16204210 2006
5
[Selection on viability of individuals heterozygous for the temperature-sensitive lethal mutation l(2)M167(DTS) in experimental populations of Drosophila melanogaster]. 61
16080600 2005
6
[The effect of male mating competitiveness, developmental rate, and viability of larvae and pupae in Drosophila melanogaster heterozygous for the temperature-sensitive lethal mutation l(2)M167DTS on the dynamics of the mutation elimination from the population]. 61
15977813 2005
7
[The effect of population density on the elimination dynamics of a recessive lethal mutation from experimental populations]. 61
15865287 2005
8
A dnaT mutant with phenotypes similar to those of a priA2::kan mutant in Escherichia coli K-12. 61
15238512 2004
9
Towards a male-only release system for SIT with the Queensland fruit fly, Bactrocera tryoni, using a genetic sexing strain with a temperature-sensitive lethal mutation. 61
12484529 2002
10
Use of a temperature-sensitive lethal mutation strain of medfly (Ceratitis capitata) for the suppression of pest populations. 61
24173945 1995
11
Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiae. 61
7958921 1994
12
Identification of an essential gene, l(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunit. 61
8415617 1993
13
The CDC42 homologue from Caenorhabditis elegans. Complementation of yeast mutation. 61
8514766 1993
14
Mutations in yeast calmodulin cause defects in spindle pole body functions and nuclear integrity. 61
1469052 1992
15
Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure. 61
1398069 1992
16
Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42. 54
2122236 1990
17
The fatty acid constitution and ordering state of membranes in dominant temperature-sensitive lethal mutation and wild-type Drosophila melanogaster larvae. 61
2168167 1990
18
[Mating behavior in Drosophila melanogaster males heterozygous for the dominant temperature-sensitive lethal mutation]. 61
2111789 1990
19
A yeast gene essential for regulation of spindle pole duplication. 61
3072479 1988
20
An eIF-4A-like protein is a suppressor of an Escherichia coli mutant defective in 50S ribosomal subunit assembly. 61
2461520 1988
21
A sex-specific, temperature-sensitive maternal effect of the daughterless mutation of Drosophila melanogaster. 61
827461 1976
22
Altered synthesis and stability of RNA polymerase holoenzyme subunits in mutants of Escherichia coli with mutations in the beta or beta' subunit genes. 61
787754 1976

Variations for Temperature-Sensitive Lethal Mutation

Expression for Temperature-Sensitive Lethal Mutation

Search GEO for disease gene expression data for Temperature-Sensitive Lethal Mutation.

Pathways for Temperature-Sensitive Lethal Mutation

GO Terms for Temperature-Sensitive Lethal Mutation

Sources for Temperature-Sensitive Lethal Mutation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
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39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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