FTLE
MCID: TMP005
MIFTS: 19

Temporal Epilepsy, Familial (FTLE)

Categories: Genetic diseases, Rare diseases

Aliases & Classifications for Temporal Epilepsy, Familial

MalaCards integrated aliases for Temporal Epilepsy, Familial:

Name: Temporal Epilepsy, Familial 20 70
Epilepsy, Familial Temporal Lobe 20
Familial Temporal Lobe Epilepsy 20
Familial Epilepsy Temporal Lobe 36
Ftle 20

Classifications:



External Ids:

KEGG 36 H00809
UMLS 70 C1842564

Summaries for Temporal Epilepsy, Familial

KEGG : 36 Autosomal dominant lateral temporal epilepsy (ADLTE) or autosomal dominant partial epilepsy with auditory features (ADPEAF) is an inherited epilepsy syndrome characterized by onset in adolescence or early adulthood of lateral temporal seizures with predominant auditory symptoms originating from the lateral temporal lobe cortex. Mutations in the leucine-rich glioma-inactivated 1 (LGI1) gene have been reported in up to 50% of ADTLE/ADPEAF pedigrees. In addition, de novo LGI1 mutations are found in about 2% of sporadic cases with idiopathic partial epilepsy with auditory features, who are clinically similar to the majority of patients with ADLTE/ADPEAF but have no family history.

MalaCards based summary : Temporal Epilepsy, Familial, also known as epilepsy, familial temporal lobe, is related to epilepsy, familial temporal lobe, 5 and epilepsy, familial temporal lobe, 7. An important gene associated with Temporal Epilepsy, Familial is ETL2 (Epilepsy, Familial Temporal Lobe). Affiliated tissues include temporal lobe and cortex.

GARD : 20 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 98819 Definition A rare, genetic epilepsy characterized by mostly benign simple or complex partial seizures with autonomic or psychic auras. Seizures occur infrequently, are of short duration and are usually well controlled with medication. Development and cognition are normal.

Related Diseases for Temporal Epilepsy, Familial

Graphical network of the top 20 diseases related to Temporal Epilepsy, Familial:



Diseases related to Temporal Epilepsy, Familial

Symptoms & Phenotypes for Temporal Epilepsy, Familial

Drugs & Therapeutics for Temporal Epilepsy, Familial

Search Clinical Trials , NIH Clinical Center for Temporal Epilepsy, Familial

Genetic Tests for Temporal Epilepsy, Familial

Anatomical Context for Temporal Epilepsy, Familial

MalaCards organs/tissues related to Temporal Epilepsy, Familial:

40
Temporal Lobe, Cortex

Publications for Temporal Epilepsy, Familial

Articles related to Temporal Epilepsy, Familial:

(show all 50)
# Title Authors PMID Year
1
Vortex dynamics and transport phenomena in stenotic aortic models using Echo-PIV. 61
33361564 2020
2
Accelerated Monte Carlo Rendering of Finite-Time Lyapunov Exponents. 61
31425098 2020
3
Evaluating the Effect of the Number of Wire of Flow Diverter Stents on the Nonstagnated Region Formation in an Aneurysm Sac Using Lagrangian Coherent Structure and Hyperbolic Time Analysis. 61
31568908 2020
4
Topological analysis of particle transport in lung airways: Predicting particle source and destination. 61
31630028 2019
5
Intermittent stickiness synchronization. 61
31212566 2019
6
Reply to Horswill and Manica: FTLE is one of a suite of oceanographic variables useful for predicting bycatch risk in marine fisheries. 61
30890641 2019
7
Chaos in wavy-stratified fluid-fluid flow. 61
30927853 2019
8
Chaotic Manifold Analysis of Four-Screw Extruders Based on Lagrangian Coherent Structures. 61
30441795 2018
9
Robotic transanal minimally invasive surgery for rectal cancer after clinical complete response to neoadjuvant chemoradiation. 61
30073747 2018
10
Reduced-order description of transient instabilities and computation of finite-time Lyapunov exponents. 61
28679218 2017
11
Backward Finite-Time Lyapunov Exponents in Inertial Flows. 61
27875210 2017
12
Lagrangian coherent structures during combustion instability in a premixed-flame backward-step combustor. 61
28085437 2016
13
Finite-time Lyapunov exponent-based analysis for compressible flows. 61
27586608 2016
14
Collective cell migration over long time scales reveals distinct phenotypes. 61
29657838 2016
15
Finite-Time Lyapunov Exponents and Lagrangian Coherent Structures in Uncertain Unsteady Flows. 61
26955037 2016
16
Reynolds number effects on mixing due to topological chaos. 61
27036184 2016
17
Lagrangian coherent structures and inertial particle dynamics. 61
27078448 2016
18
Large-deviation statistics of vorticity stretching in isotropic turbulence. 61
27078458 2016
19
Refining finite-time Lyapunov exponent ridges and the challenges of classifying them. 61
26328581 2015
20
Attracting Lagrangian coherent structures on Riemannian manifolds. 61
26328582 2015
21
Oseledets' splitting of standard-like maps. 61
25725649 2015
22
Local-heterogeneous responses and transient dynamics of cage breaking and formation in colloidal fluids. 61
25217951 2014
23
Competitive autocatalytic reactions in chaotic flows with diffusion: prediction using finite-time Lyapunov exponents. 61
24697371 2014
24
Genetics advances in autosomal dominant focal epilepsies: focus on DEPDC5. 61
25194487 2014
25
Do Finite-Size Lyapunov Exponents detect coherent structures? 61
24387565 2013
26
Integrated computation of finite-time Lyapunov exponent fields during direct numerical simulation of unsteady flows. 61
23556982 2013
27
A time-dependent vector field topology based on streak surfaces. 61
22614331 2013
28
Quantifying stretching and rearrangement in epithelial sheet migration. 61
23599682 2013
29
Lagrangian motion, coherent structures, and lines of persistent material strain. 61
22809180 2013
30
Lagrangian Coherent Structures for Design Analysis of Revolving Doors. 61
26357123 2012
31
Characterization of the transport topology in patient-specific abdominal aortic aneurysm models. 61
22952409 2012
32
Interactive computation and rendering of Finite-time Lyapunov Exponent fields. 61
22291157 2012
33
Analysis of time-dependent flow-sensitive PC-MRI data. 61
21519102 2012
34
Lagrangian transport properties of pulmonary interfacial flows. 61
23049141 2011
35
Focal epilepsy of probable temporal lobe origin in a Gypsy family showing linkage to a novel locus on 7p21.3. 61
21645995 2011
36
Lagrangian coherent structures and the smallest finite-time Lyapunov exponent. 61
21721757 2011
37
Interactive separating streak surfaces. 61
20975199 2010
38
Mathematical modeling and simulation of seated stability. 61
20018288 2010
39
The computation of finite-time Lyapunov exponents on unstructured meshes and for non-Euclidean manifolds. 61
20370295 2010
40
Fast computation of finite-time Lyapunov exponent fields for unsteady flows. 61
20370293 2010
41
Accurate extraction of Lagrangian coherent structures over finite domains with application to flight data analysis over Hong Kong International Airport. 61
20370292 2010
42
Partial epilepsy syndrome in a Gypsy family linked to 5q31.3-q32. 61
19400876 2009
43
Lagrangian coherent structures in low Reynolds number swimming. 61
21825514 2009
44
Do Japanese style acupuncture and moxibustion reduce symptoms of the common cold? 61
18955215 2008
45
Efficient computation and visualization of coherent structures in fluid flow applications. 61
17968098 2007
46
Non-invasive measurement of instantaneous forces during aquatic locomotion: a case study of the bluegill sunfish pectoral fin. 61
17267654 2007
47
Magnetic resonance imaging abnormalities in familial temporal lobe epilepsy with auditory auras. 61
14623726 2003
48
Preoperative radiation with or without chemotherapy and full-thickness transanal excision for selected T2 and T3 distal rectal cancers. 61
12018456 2002
49
Familial temporal lobe epilepsy autosomal dominant inheritance in a large pedigree from southern Italy. 61
10642040 2000
50
Radical and local excisional methods of sphincter-sparing surgery after high-dose radiation for cancer of the distal 3 cm of the rectum. 61
7641018 1995

Variations for Temporal Epilepsy, Familial

Expression for Temporal Epilepsy, Familial

Search GEO for disease gene expression data for Temporal Epilepsy, Familial.

Pathways for Temporal Epilepsy, Familial

GO Terms for Temporal Epilepsy, Familial

Sources for Temporal Epilepsy, Familial

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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