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MCID: TND005
MIFTS: 54

Tendinitis

Categories: Muscle diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Tendinitis

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MalaCards integrated aliases for Tendinitis:

Name: Tendinitis 40 12 54 42 15 71
Tendinopathy 44 71

Classifications:

MalaCards categories:
Anatomical: Muscle diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:971
MeSH 44 D052256
NCIt 50 C97141
SNOMED-CT 67 312785002
ICD10 32 M77.9
UMLS 71 C0039503 C1568272
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Summaries for Tendinitis

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MedlinePlus : 42 Tendons are flexible bands of tissue that connect muscles to bones. They help your muscles move your bones. Tendinitis is the severe swelling of a tendon. Tendinitis usually happens after repeated injury to an area such as the wrist or ankle. It causes pain and soreness around a joint. Some common forms of tendinitis are named after the sports that increase their risk. They include tennis elbow, golfer's elbow, pitcher's shoulder, swimmer's shoulder, and jumper's knee. Doctors diagnose tendinitis with your medical history, a physical exam, and imaging tests. The first step in treatment is to reduce pain and swelling. Rest, wrapping or elevating the affected area, and medicines can help. Ice is helpful for recent, severe injuries. Other treatments include ultrasound, physical therapy, steroid injections, and surgery.

MalaCards based summary : Tendinitis, also known as tendinopathy, is related to calcific tendinitis and bicipital tenosynovitis, and has symptoms including muscle weakness, back pain and myalgia. An important gene associated with Tendinitis is ACP5 (Acid Phosphatase 5, Tartrate Resistant), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PI3K-Akt signaling pathway. The drugs Polidocanol and Diclofenac have been mentioned in the context of this disorder. Affiliated tissues include bone, spinal cord and bone marrow, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 74 Tendinopathy, also known as tendinitis or tendonitis, is a type of tendon disorder that results in pain,... more...

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Related Diseases for Tendinitis

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Diseases related to Tendinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 648)
# Related Disease Score Top Affiliating Genes
1 calcific tendinitis 32.8 SPP1 CRP
2 bicipital tenosynovitis 31.9 PRTN3 CRP
3 spondylitis 30.4 TNF IL6 IL1B CRP
4 compartment syndrome 30.3 TNF IL6 CRP
5 bursitis 30.3 TNF TAC1 MMP3 IL6 IL1B CRP
6 shoulder impingement syndrome 30.1 TNMD TAC1
7 epicondylitis 30.1 TNMD TAC1 DCN
8 back pain 30.1 IL6 IL1B
9 spondyloarthropathy 30.1 TNF MMP3 IL6 IL1B
10 plantar fasciitis 30.1 VEGFA TAC1 CRP
11 vasculitis 30.0 TNF PRTN3 IL6 CRP
12 cellulitis 29.9 TNF IL6 CRP
13 erythema nodosum 29.9 TNF IL6 IL1B CRP
14 necrotizing fasciitis 29.9 IL6 IL1B CRP
15 plague 29.8 TNF IL6 IL1B
16 hyperthyroidism 29.8 PRTN3 IL6 CRP ACP5
17 prostatitis 29.8 TNF IL6 IL1B
18 alcoholic liver cirrhosis 29.7 TNF IL6 IL1B
19 pain agnosia 29.7 TNF TAC1 IL6 IL1B
20 pharyngitis 29.7 TNF IL6 IL1B CRP
21 pyelonephritis 29.7 TNF IL6 IL1B CRP
22 typhoid fever 29.7 TNF IL6 IL1B CRP
23 carpal tunnel syndrome 29.7 VEGFA TAC1 IL6 IL1B COMP
24 lyme disease 29.7 TNF IL6 IL1B CRP
25 blau syndrome 29.7 VEGFA TNF IL1B
26 fibromyalgia 29.7 TNF IL6 IL1B CRP
27 neuritis 29.7 VEGFA TNF IL6 IL1B
28 otitis media 29.6 TNF IL6 IL1B CRP
29 disease by infectious agent 29.6 TNF PRTN3 IL6 IL1B CRP
30 acute pancreatitis 29.6 TNF IL6 IL1B CRP
31 amyloidosis 29.6 TNF IL6 IL1B CRP
32 celiac disease 1 29.6 TNF IL6 IL1B CRP
33 osteonecrosis 29.6 VEGFA TNF IL1B ACP5
34 osteomyelitis 29.5 TNF IL6 IL1B CRP ACP5
35 spondyloarthropathy 1 29.5 TNF PRTN3 MMP3 IL6 CRP
36 ulcerative colitis 29.4 TNF PRTN3 IL6 IL1B CRP
37 bone resorption disease 29.4 TNF SPP1 IL6 IL1B CRP ACP5
38 arthropathy 29.3 TNF MMP3 MMP13 IL6 IL1B CRP
39 osteoarthritis 29.3 TNF MMP3 MMP13 IL6 IL1B CRP
40 meningitis 29.2 VEGFA TNF IL6 IL1B CRP
41 congestive heart failure 29.2 VEGFA TNF IL6 IL1B CRP
42 reactive arthritis 29.2 TNF PRTN3 IL6 IL1B CRP COMP
43 type 1 diabetes mellitus 29.2 VEGFA TNF IL6 IL1B CRP
44 kidney disease 29.2 VEGFA TNF SPP1 PRTN3 IL6 CRP
45 tenosynovitis 29.2 TNF SLC40A1 SH2D3A PRTN3 MMP3 IL6
46 bronchitis 29.2 TNF TAC1 IL6 IL1B CRP
47 body mass index quantitative trait locus 11 29.1 VEGFA TNF MMP3 IL6 IL1B G6PC1
48 liver cirrhosis 29.1 VEGFA TNF IL6 IL1B G6PC1 CRP
49 diabetes mellitus 28.8 VEGFA TNF SPP1 MMP3 IL6 IL1B
50 psoriatic arthritis 28.8 VEGFA TNF MMP3 IL6 IL1B CRP

Graphical network of the top 20 diseases related to Tendinitis:



Diseases related to Tendinitis
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Symptoms & Phenotypes for Tendinitis

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UMLS symptoms related to Tendinitis:


muscle weakness, back pain, myalgia, sciatica, muscle cramp, muscle rigidity, muscle spasticity

MGI Mouse Phenotypes related to Tendinitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.25 COMP CRP DCN G6PC1 IL1B IL6
2 cardiovascular system MP:0005385 10.21 COMP CRP IL1B IL6 MMP13 PDGFA
3 immune system MP:0005387 10.15 COMP CRP DCN IL1B IL6 MMP3
4 integument MP:0010771 10.06 DCN IL1B IL6 MMP13 PDGFA PDGFB
5 muscle MP:0005369 9.91 COMP DCN IL6 PDGFA PDGFB SPP1
6 neoplasm MP:0002006 9.7 DCN G6PC1 IL1B IL6 SPP1 TNF
7 renal/urinary system MP:0005367 9.61 DCN G6PC1 IL6 PDGFA PDGFB SLC40A1
8 skeleton MP:0005390 9.44 COMP DCN G6PC1 IL1B IL6 MMP13
Sources

Drugs & Therapeutics for Tendinitis

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Drugs for Tendinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 157)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Polidocanol Approved Phase 4 9002-92-0
2
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
3
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
4
Etanercept Approved, Investigational Phase 4 185243-69-0
5
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
6
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
7
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
8
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
9
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
10
Cortisone Experimental Phase 4 53-06-5 222786
11 Protective Agents Phase 4
12 Gastrointestinal Agents Phase 4
13 Sclerosing Solutions Phase 4
14 Cyclooxygenase 2 Inhibitors Phase 4
15 Viscosupplements Phase 4
16 Adjuvants, Immunologic Phase 4
17 Respiratory System Agents Phase 4
18 Anti-Asthmatic Agents Phase 4
19
Ibuprofen Approved Phase 3 15687-27-1 3672
20
Copper Approved, Investigational Phase 3 7440-50-8 27099
21
Selenium Approved, Investigational, Vet_approved Phase 3 7782-49-2
22
Zinc Approved, Investigational Phase 3 7440-66-6 32051
23
Ropivacaine Approved Phase 2, Phase 3 84057-95-4 71273 175805
24
Clonidine Approved Phase 3 4205-90-7 2803
25
Etodolac Approved, Investigational, Vet_approved Phase 3 41340-25-4 3308
26
Ketamine Approved, Vet_approved Phase 2, Phase 3 6740-88-1 3821
27
Glycolic acid Approved, Investigational Phase 3 79-14-1 757
28
Ketoprofen Approved, Vet_approved Phase 3 22071-15-4 3825
29
Manganese Approved, Nutraceutical Phase 3 7439-96-5 27854
30
Glutamic acid Approved, Nutraceutical Phase 2, Phase 3 56-86-0 33032
31 Calcium, Dietary Phase 3
32 Copper Supplement Phase 3
33 Adrenergic alpha-Agonists Phase 3
34 Adrenergic Agents Phase 3
35 Sympathomimetics Phase 3
36 Adrenergic Agonists Phase 3
37 Vasoconstrictor Agents Phase 3
38 Adrenergic beta-Agonists Phase 3
39 Sympatholytics Phase 3
40 Antihypertensive Agents Phase 3
41 Mydriatics Phase 3
42 Bronchodilator Agents Phase 3
43 Mitogens Phase 2, Phase 3
44 Neurotransmitter Agents Phase 2, Phase 3
45 Excitatory Amino Acid Antagonists Phase 2, Phase 3
46 Anesthetics, Intravenous Phase 2, Phase 3
47 Anesthetics, Dissociative Phase 2, Phase 3
48 Anesthetics, General Phase 2, Phase 3
49 Carboxymethylcellulose Sodium Phase 3
50
Calcium Nutraceutical Phase 3 7440-70-2 271

Interventional clinical trials:

(show top 50) (show all 292)
# Name Status NCT ID Phase Drugs
1 Insertional Achilles Tendinopathy: A Randomized Trial to Evaluate the Effectiveness of Transferring the Flexor Hallucis Longus Tendon Unknown status NCT01341509 Phase 4
2 A Single-blinded Randomized Controlled Trial Comparing Patients Who Receive a Corticosteroid Injection for Nontraumatic Degenerative Rotator Cuff Tears or Tendinopathy and Scheduled Use of a Dynamic Elastic Garment to Patients Who Receive a Corticosteroid Injection Alone. Unknown status NCT03032432 Phase 4 Corticosteroid injection
3 Functional Improvement and Ultrasound Tissue Characterisation of the Achilles Tendon Following Sodium Hyaluronate Injection for Plantaris Friction Syndrome Unknown status NCT03077009 Phase 4 Hyaluronic Acid
4 The Effect of Platelet Rich Plasma on Partial Thickness Rotator Cuff Tears: A Randomized Controlled Trial Completed NCT04743986 Phase 4 Corticosteroid (CS)
5 Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection: A Double Blind Controlled Study Completed NCT02403856 Phase 4 Sodium Chloride 0.9%;Methylprednisolone acetate
6 Prospective Double-blind Randomized Clinical Trial Comparing Gait Analysis and Clinical Function After Metal on Metal Total Hip Arthroplasty With Large Diameter Femoral Head and Metal on Metal Total Hip Resurfacing. Completed NCT04516239 Phase 4
7 The Value of Platelet-Rich Plasma in Chronic Midportion Achilles Tendinopathy: a Double-blind Randomized Clinical Trial Completed NCT00761423 Phase 4
8 Placebo Controlled Trial, Testing the Efficacy of Polidocanol Injections as a Treatment of Chronic Achilles Tendinopathy. Completed NCT00377910 Phase 4 Aethoxysclerol
9 The Value of a High-Volume Image-Guided Injection in Chronic Midportion Achilles Tendinopathy: a Double-blind, Randomized, Placebo-controlled Clinical Trial Completed NCT02996409 Phase 4 HVIGI;LVIGI
10 Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to a Single Intrabursal Injection of Corticosteroids in Patients With Shoulder Calcific Tendinopathy Completed NCT01652495 Phase 4 methylprednisolone acetate;Triamcinolone Acetonide
11 "NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes" Completed NCT00792376 Phase 4 etoricoxib;diclofenac
12 Shockwave Therapy of Chronic Achilles Tendinopathy. A Double-blind, Randomized Clinical Trial of Efficacy Completed NCT00958620 Phase 4
13 Radiofrequency-based Plasma Microdebridement Compared to Surgical Microdebridement for Treating Achilles Tendinosis: A Prospective, Randomized, Controlled Multi-Center Study" Completed NCT00534781 Phase 4
14 Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer: A Prospective, Randomized, Controlled Trial Completed NCT00950053 Phase 4
15 A Prospective Study of the Use of the Madrid Ultrasound Scoring System in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With Spondyloarthritis Completed NCT02960035 Phase 4 50mg etanercept;25mg etanercept;placebo
16 Evaluation of Clinical Efficacy and Comparison of Autologous Platelet Rich Plasma, Hyaluronic Acid, Corticosteroid and Saline Injections for Treating Lateral and Medial Humeral Epicondylopathy Recruiting NCT04521387 Phase 4 Platelet Rich Plasma;Corticosteroid Injection;Hyaluronic Acid Injection
17 Collagen and PRP in Partial Thickness Rotator Cuff Injuries: Friends or Only Indifferent Neighbors: Randomized Controlled Trial Recruiting NCT04492748 Phase 4
18 Betamethason Versus Ketorolac Injection for the Treatment of DeQuervains Tenosynovitis Active, not recruiting NCT02604537 Phase 4 betamethasone;Ketorolac
19 Achilles Tendinopathy Treated With Heavy Slow Resistance Training Supplemented With Injection of Glucocorticosteroid or Local Anaesthetic. Active, not recruiting NCT02580630 Phase 4 Ultrasound guided injection with Glucocorticosteroid;Ultrasound guided injection with local anaestethic
20 Comparative Effectiveness of Particulate Versus Nonparticulate Corticosteroid Injections for the Treatment of Musculoskeletal Conditions Not yet recruiting NCT04278833 Phase 4 Triamcinolone or Betamethasone;Dexamethasone
21 Calcific Tendonitis Treatment: Barbotage vs. Barbotage With Cortisone Injection: A Randomized Controlled Double-Blind Study Not yet recruiting NCT04126278 Phase 4 Barbotage;Dexamethasone
22 Comparison of Leukocyte-rich Platelet Rich Plasma Injection to Percutaneous Tenotomy in the Treatment of Chronic Common Extensor Tendinopathy Not yet recruiting NCT04384809 Phase 4
23 Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial Suspended NCT04115644 Phase 4 Ketorolac;Marcaine (placebo);Kenalog
24 Ultrasound-Guided Platelet Rich Plasma Versus Whole Blood Injection for the Treatment of Gluteus Medius Tendinopathy: A Double-Blind Randomized Controlled Study Terminated NCT02978833 Phase 4
25 "Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis" Withdrawn NCT00420875 Phase 4
26 A Prospective Clinical Trial Comparing the Efficacy of Brisement to Physical Therapy for the Treatment of Achilles Tendinosis Withdrawn NCT03363789 Phase 4
27 A Randomized Single Blinded Prospective Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients Withdrawn NCT03319784 Phase 4 Ketorolac;Triamcinolone Acetonide
28 Eccentric Training With Our Without Elbow Brace for Epicondylitis - a Randomized Clinical Trial Unknown status NCT01273688 Phase 3
29 Treatment of Subacromial Shoulder Pain Unknown status NCT01441830 Phase 3
30 Clinical Multicenter, Phase III, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Ibuprofen 50mg/g Gel in the Treatment of Patients With Muscle Pain, Joint, or Pain Caused by Sprains, Contusions, Tendinitis, or Myofascial Compared to Profenid ® 25mg/g. Gel Unknown status NCT01373697 Phase 3 Ibuprofen;Profenid
31 Treatment for Achilles Tendinopathy Unknown status NCT00835939 Phase 2, Phase 3 25% Dextrose and 1% Lidocaine;Lidocaine
32 Multicenter, Randomized, Double-blind Trial to Evaluate the Efficacy and Safety Aliviador Compared to Gelol in the Relief in Patients With Contusons, Sprains,Trauma and Muscle Injury. Unknown status NCT01097798 Phase 3 Aliviador;Gelol
33 Vibration Training in Epicondylitis - a Randomized Trial Unknown status NCT01269879 Phase 3
34 A Randomized Clinical Trial Comparing the Effectiveness of Subacromial Decompression (Acromioplasty) Versus Subacromial Bursectomy (no Acromioplasty) in the Arthroscopic Treatment of Patients With Rotator Cuff Tendinosis Unknown status NCT00196573 Phase 3
35 Clinical Multicenter Study, Randomized, Open, to Evaluate the Efficacy and Safety of Salonsip Compared to Sabiá Plaster Relief of the Signs and Symptoms in Patients With Contusions, Sprains, Injuries and Muscular Injuries With Less Than 24 Hours Early or Holders of Myalgia, Pain and Tendonitis in Regions Miofasciais Articulated. Unknown status NCT00970658 Phase 3 Salonsip plaster;Sabia plaster
36 Epidemiology of Incidents and Accidents in Sport. Influence of Moisture. Unknown status NCT02346786 Phase 3
37 Pilot Randomized Controlled Trial to Evaluate Safety and Efficacy of Percutaneous Needle Tenotomy With Platelet Rich Plasma (Leukocyte Depleted)in Epicondylitis Completed NCT01945528 Phase 3 US-guided tenotomy with PRP;US-guided tenotomy with lidocaine
38 A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Diclofenac Sodium Patch for the Topical Treatment of Pain Due to Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3 diclofenac sodium;Matching Placebo
39 URINARY INCONTINENCE AND URO-GENITAL PROLAPSE: A RANDOMIZED TRIAL OF PELVIC ORGAN PROLAPSE REPAIR PLUS MINI-SLING VERSUS PELVIC ORGAN PROLAPSE REPAIR ALONE Completed NCT01384084 Phase 3
40 The Value of Autologous Tenocyte Implantation in Patients With Chronic Achilles Tendinopathy: a Double-blind Randomised Clinical Trial Completed NCT01343836 Phase 2, Phase 3
41 Role of Biological Therapy in Rotator Cuff Tendinopathy. Effectiveness of Plasma Rich in Growth Factors Regarding Functional Capacity and Pain Compared With the Conventional Treatment Using Steroids Completed NCT01915979 Phase 3 Celestone cronodose (Bethametasone)
42 Impact of Peripheral Pain Perception on Central Sensitization and Movement Strategies in Patients With Chronic Achilles Tendinopathy Completed NCT03316378 Phase 2, Phase 3 Ropivacaine injection
43 Analgesic Benefit of PECS Blocks for Biceps Tenodesis Shoulder Surgery Completed NCT02741713 Phase 3 Solution for Injection in Interscalene Block;Solution for Injection in Sham Block;Solution for Injection PECS Blocks
44 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase III Study of the Efficacy, Tolerability and Safety of Ketoprofen Topical Patch, 20% (KTP) in the Treatment of Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee Completed NCT00352625 Phase 3 Ketoprofen Topical Patch 20%
45 A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder Completed NCT01161615 Phase 3 MRX-7EAT;Placebo
46 A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Topical Patch in the Treatment of Pain Due to Recent Onset Supraspinatous and/or Subacromial Tendonitis/Bursitis and/or Subdeltoid Bursitis of Shoulder Completed NCT01506154 Phase 3 MRX-7EAT
47 Does Subacromial Injection With Glutamate Receptor (NMDAR) Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy? Recruiting NCT02967640 Phase 2, Phase 3 Ketalar;NaCl 9%
48 Great Trochanteric Pain Syndrome: Parallel Group, Blind Randomised Clinical Trial to Assess the Efficacy and Safety of PRP Injection Versus Needle Tenotomy With Lidocaine Recruiting NCT04231357 Phase 3 platelet rich plasma
49 Use of Extended Release Triamcinolone in the Treatment of Rotator Cuff Disease Recruiting NCT04094298 Phase 3 FX006 Injection
50 Evaluation of Regenerative Medicine Treatment Outcomes With Amniotic Fluid for Musculoskeletal Conditions Recruiting NCT03390920 Phase 2, Phase 3

Search NIH Clinical Center for Tendinitis

Cochrane evidence based reviews: tendinopathy

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Genetic Tests for Tendinitis

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Anatomical Context for Tendinitis

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MalaCards organs/tissues related to Tendinitis:

40
Bone, Spinal Cord, Bone Marrow, Skin, Whole Blood, Pituitary, Hypothalamus
Sources

Publications for Tendinitis

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Articles related to Tendinitis:

(show top 50) (show all 6099)
# Title Authors PMID Year
1
Basic Science of Tendinopathy and Novel Treatments: An Update. 61 42
33438935 2021
2
CALCIFIC TENDINOPATHY: CALCIUM DEPOSIT MORPHOLOGY DIRECTLY AFFECTS PAIN AND FUNCTION OF THE SHOULDER. 42 61
33456114 2020
3
Corticosteroids vs autologous blood injection for lateral epicondylitis: Study protocol for a cohort trial. 42
33371166 2020
4
Involvement of the subacromial bursa in impingement syndrome of the shoulder as judged by expression of tenascin-C and histopathology. 61 54
12678373 2003
5
Atypical femoral fracture as the cause of greater trochanteric pain syndrome - a case report. 61
33598061 2021
6
Participant characteristics are poorly reported in exercise trials in tendinopathy: A systematic review. 61
33360409 2021
7
Diagnosing Achilles tendinopathy is like delicious spaghetti carbonara: it is all about key ingredients, but not all chefs use the same recipe. 61
33055134 2021
8
Proximal hamstring tendinopathy; expert physiotherapists' perspectives on diagnosis, management and prevention. 61
33378733 2021
9
Which treatment is most effective for patients with Achilles tendinopathy? A living systematic review with network meta-analysis of 29 randomised controlled trials. 61
32522732 2021
10
Emerging Biological Treatment Methods for Ankle Joint and Soft Tissue Conditions: Clinical Applications as Alternative or Adjuvant. 61
33487242 2021
11
Low Molecular-weight Hyaluronic Acid Versus Physiotherapy for the Treatment of Supraspinatus Tendinopathy: A Randomized Comparative Clinical Trial. 61
33591125 2021
12
Effects of shockwave therapy on pain and disability in individuals with rotator cuff tendinopathy: a systematic review protocol. 61
33570316 2021
13
Translation, cross-cultural adaptation and validation of the Brazilian Portuguese version of the Victorian Institute of Sports Assessment for Gluteal Tendinopathy patient reported-outcome measure (VISA-G.BR). 61
33581429 2021
14
Effects of a "toes-off" modified heel raise on muscle coordination in non-dancers, dancers, and dancers with flexor hallucis longus tendinopathy. 61
33601167 2021
15
Biomechanical Comparison of All-Soft Suture Anchor Single-Row vs Double-Row Bridging Construct for Insertional Achilles Tendinopathy. 61
33030070 2021
16
High- Versus Low-Molecular-Weight Hyaluronic Acid for the Treatment of Rotator Cuff Tendinopathy: A Triple-Blind Randomized Comparative Trial. 61
33567859 2021
17
Platelet-Rich Plasma in Patients With Partial-Thickness Rotator Cuff Tears or Tendinopathy Leads to Significantly Improved Short-Term Pain Relief and Function Compared With Corticosteroid Injection: A Double-Blind Randomized Controlled Trial. 61
33127554 2021
18
Flexor hallucis longus hypertrophy secondary to Achilles tendon tendinopathy: an MRI-based case-control study. 61
33555443 2021
19
French Translation and Validation of the Victorian Institute of Sports Assessment for Gluteal Tendinopathy Questionnaire. 61
32323468 2021
20
Line- and Point-Focused Extracorporeal Shock Wave Therapy for Achilles Tendinopathy: A Placebo-Controlled RCT Study. 61
33586526 2021
21
Telehealth sounds a bit challenging, but it has potential: participant and physiotherapist experiences of gym-based exercise intervention for Achilles tendinopathy monitored via telehealth. 61
33541314 2021
22
A comparative study of treatment interventions for patellar tendinopathy: a randomized controlled trial. 61
33556350 2021
23
Endoscopic Flexor Hallucis Longus Transfer for Achilles Noninsertional Tendinopathy: Description of Surgical Technique and Functional Outcomes. 61
31916453 2021
24
Endoscopic speed bridge: a new treatment for insertional Achilles tendinopathy. 61
33578040 2021
25
Author Correction: Tendinopathy. 61
33536420 2021
26
Does balneotherapy provide additive effects to physical therapy in patients with subacute supraspinatus tendinopathy? A randomized, controlled, single-blind study. 61
33089368 2021
27
Diagnostic criteria for musculoskeletal disorders for use in occupational healthcare or research: a scoping review of consensus- and synthesised-based case definitions. 61
33573616 2021
28
Immediate and long-term effects of mechanical loading on Achilles tendon volume: A systematic review and meta-analysis. 61
33556887 2021
29
Mycobacterium mageritense infection following mastectomy and breast reconstruction requiring triple antibiotic therapy and surgical debridement. 61
33542012 2021
30
Safety and Tolerability of Fluoroquinolones in Patients with Staphylococcal Periprosthetic Joint Infections. 61
33606003 2021
31
Efficacy of Adjuvant Application of Platelet-Rich Plasma After Needle Aspiration of Calcific Deposits for the Treatment of Rotator Cuff Calcific Tendinitis: A Double-Blinded, Randomized Controlled Trial With 2-Year Follow-up. 61
33566629 2021
32
Favourable clinical outcome of shoulder manipulation for chronic calcific tendinitis associated with shoulder stiffness: A case report. 61
33546934 2021
33
Machine learning algorithms trained with pre-hospital acquired history-taking data can accurately differentiate diagnoses in patients with hip complaints. 61
33573429 2021
34
Capsular resection versus capsular repair in direct anterior approach for total hip arthroplasty: a randomized controlled trial. 61
33517727 2021
35
A histological study on the tendons at chiasma plantare in pes cavus. 61
33129658 2021
36
Patient-Related Outcomes of Arthroscopic Resection of Ganglion Cysts of the Wrist. 61
33552692 2021
37
Bicipital groove cross-sectional area on ultrasonography: Does a correlation to intra-articular tendon pathology exist? 61
33333282 2021
38
The plantaris muscle - Anatomical curiosity or a structure with important clinical value? - A comprehensive review of the current literature. 61
33561523 2021
39
Shear wave and strain sonoelastography for the evaluation of the Achilles tendon during isometric contractions. 61
33598763 2021
40
Normative Parameters of Gastrocnemius Muscle Stiffness and Associations with Patient Characteristics and Function. 61
33604133 2021
41
Scapular Motion in the Presence of Rotator Cuff Tears: A Systematic Review. 61
33540119 2021
42
Metabolic Regulation of Tendon Inflammation and Healing Following Injury. 61
33569739 2021
43
UTE T2* mapping of tendinopathic patellar tendons: an MRI reproducibility study. 61
32340475 2021
44
Intra-Fascicular Chondroid-like Bodies in the Ageing Equine Superficial Digital Flexor Tendon comprise Glycosaminoglycans and Type II Collagen. 61
33580534 2021
45
A Novel Murine Muscle Loading Model to Investigate Achilles Musculotendinous Adaptation. 61
33571057 2021
46
2019 Marathon of Rome. Hamstring injuries in long distance runners: influence of age, gender, weight, height, numbers of marathon and impact profile. 61
33586934 2021
47
Proximal Hamstring Tendon Injuries: Diagnosis and Management. 61
33546782 2021
48
Diagnostic ultrasound in patients with shoulder pain: An inter-examiner agreement and reliability study among Dutch physical therapists. 61
33348286 2021
49
The impact of COVID-19 on shoulder and elbow trauma in a skeletally immature population: an Italian survey. 61
32984859 2021
50
US-guided percutaneous irrigation of calcific tendinopathy of the rotator cuff in patients with or without previous external shockwave therapy. 61
32451885 2021
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Variations for Tendinitis

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Expression for Tendinitis

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Search GEO for disease gene expression data for Tendinitis.
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Pathways for Tendinitis

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Pathways related to Tendinitis according to GeneCards Suite gene sharing:

(show all 37)
# Super pathways Score Top Affiliating Genes
1
Cytokine Signaling in Immune system 65
Show member pathways
 13.32 VEGFA TNF PRTN3 PDGFB PDGFA MMP3
2
PI3K-Akt signaling pathway 36
Show member pathways
 12.81 VEGFA TNF SPP1 PDGFB PDGFA IL6
3
MAPK signaling pathway 36 1
12.72 VEGFA TNF PDGFB PDGFA IL1B
4
NF-KappaB Family Pathway 63
Show member pathways
 12.66 TNF PDGFB PDGFA IL6 IL1B
5
Degradation of the extracellular matrix 65
Show member pathways
 12.63 SPP1 PDGFB PDGFA MMP3 MMP13 DCN
6
Immune response IL-23 signaling pathway 23
Show member pathways
 12.55 TNF PDGFB PDGFA IL6 IL1B
7
Folate Metabolism 1
Show member pathways
 12.29 TNF IL6 IL1B CRP
8
IL-17 Family Signaling Pathways 64
Show member pathways
 12.29 TNF MMP3 MMP13 IL6 IL1B
9
Immune response IFN alpha/beta signaling pathway 23
Show member pathways
 12.24 TNF PDGFB PDGFA IL6 IL1B
10
Fluid shear stress and atherosclerosis 36
12.04 VEGFA TNF PDGFB PDGFA IL1B
11
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
11.94 VEGFA TNF TAC1 IL6 IL1B G6PC1
12
TNF signaling pathway 36
11.93 TNF MMP3 IL6 IL1B
13
AGE-RAGE signaling pathway in diabetic complications 36
11.88 VEGFA TNF IL6 IL1B
14
Interleukin-4 and 13 signaling 65
11.86 VEGFA TNF MMP3 IL6 IL1B
15
Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.85 SPP1 PDGFB IL6 DCN
16
Neural Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.75 VEGFA PDGFB PDGFA
17
Th1 Differentiation Pathway 64
Show member pathways
 11.73 TNF IL6 IL1B
18
Pertussis 36
11.72 TNF IL6 IL1B
19
Dendritic Cells Developmental Lineage Pathway 64
11.71 TNF IL6 IL1B
20
Endochondral Ossification 1
11.64 VEGFA SPP1 MMP13
21
Legionellosis 36
11.57 TNF IL6 IL1B
22
Malaria 36
11.51 TNF IL6 IL1B COMP
23
Interleukin-10 signaling 65
11.5 TNF IL6 IL1B
24
Differentiation Pathway 1
11.46 VEGFA PDGFB PDGFA IL6
25
Vemurafenib Pathway, Pharmacodynamics 60
11.44 VEGFA PDGFB PDGFA
26
Transcription_Role of VDR in regulation of genes involved in osteoporosis 23
11.41 TNF SPP1 IL6 IL1B
27
Rheumatoid arthritis 36
11.4 VEGFA TNF MMP3 IL6 IL1B ACP5
28
African trypanosomiasis 36
11.36 TNF IL6 IL1B
29
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.35 VEGFA TNF MMP3 IL6 IL1B
30
IL-10 Pathway 63
11.33 TNF IL6 IL1B
31
Development and heterogeneity of the ILC family 1
11.28 TNF IL6 IL1B
32
Antifolate resistance 36
11.26 TNF IL6 IL1B
33
Cytokines and Inflammatory Response 1
11.09 TNF PDGFA IL6 IL1B
34
Overview of nanoparticle effects 1
11 TNF IL6 CRP
35
G-protein signaling_Rap2B regulation pathway 23
10.97 TNF SPP1 PDGFB PDGFA IL6 IL1B
36
Osteoclast Signaling 1
10.92 SPP1 PDGFB ACP5
37
Lung fibrosis 1
10.9 TNF SPP1 PDGFB PDGFA IL6 IL1B
Sources

GO Terms for Tendinitis

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Cellular components related to Tendinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.83 VEGFA TNF TAC1 SPP1 PRTN3 PDGFB
2 extracellular matrix GO:0031012 9.55 VEGFA MMP3 MMP13 DCN COMP
3 extracellular space GO:0005615 9.5 VEGFA TNF TAC1 SPP1 PRTN3 PDGFB
4 platelet alpha granule lumen GO:0031093 9.43 VEGFA PDGFB PDGFA

Biological processes related to Tendinitis according to GeneCards Suite gene sharing:

(show all 36)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 10.07 VEGFA PRTN3 PDGFB PDGFA IL6 IL1B
2 positive regulation of gene expression GO:0010628 10.03 VEGFA TNF PDGFB IL6 IL1B CRP
3 cell-cell signaling GO:0007267 9.96 TAC1 PDGFA IL1B CCL8
4 positive regulation of protein kinase B signaling GO:0051897 9.93 VEGFA TNF PDGFB PDGFA
5 animal organ morphogenesis GO:0009887 9.92 TNF PDGFA DCN COMP
6 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.89 VEGFA TNF PDGFB PDGFA CCL8
7 cytokine-mediated signaling pathway GO:0019221 9.88 VEGFA TNF PRTN3 MMP3 IL6 IL1B
8 positive regulation of MAPK cascade GO:0043410 9.87 VEGFA PDGFB PDGFA IL6
9 regulation of insulin secretion GO:0050796 9.83 TNF IL6 IL1B
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.83 VEGFA TNF IL6
11 positive regulation of smooth muscle cell proliferation GO:0048661 9.82 TNF PDGFB IL6
12 positive regulation of interleukin-8 production GO:0032757 9.81 TNF IL6 IL1B
13 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.81 VEGFA TNF SH2D3A IL6
14 positive regulation of protein complex assembly GO:0031334 9.8 VEGFA TNF MMP3
15 monocyte chemotaxis GO:0002548 9.79 PDGFB IL6 CCL8
16 collagen catabolic process GO:0030574 9.78 PRTN3 MMP3 MMP13
17 positive regulation of MAP kinase activity GO:0043406 9.76 VEGFA TNF PDGFB PDGFA
18 negative regulation of neurogenesis GO:0050768 9.71 TNF IL6 IL1B
19 positive regulation of protein autophosphorylation GO:0031954 9.7 VEGFA PDGFB PDGFA
20 inflammatory response GO:0006954 9.7 TNF TAC1 SPP1 IL6 IL1B CRP
21 regulation of neuroinflammatory response GO:0150077 9.67 MMP3 IL6
22 regulation of establishment of endothelial barrier GO:1903140 9.67 TNF IL1B
23 positive regulation of cell division GO:0051781 9.67 VEGFA PDGFB PDGFA IL1B
24 negative regulation of platelet activation GO:0010544 9.65 PDGFB PDGFA
25 growth plate cartilage development GO:0003417 9.65 MMP13 COMP
26 positive regulation of glial cell proliferation GO:0060252 9.65 TNF IL6 IL1B
27 positive regulation of fever generation GO:0031622 9.62 TNF IL1B
28 positive regulation of neuroinflammatory response GO:0150078 9.61 TNF IL6 IL1B
29 sequestering of triglyceride GO:0030730 9.6 TNF IL1B
30 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.58 TNF IL1B
31 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway GO:0035793 9.58 PDGFB PDGFA
32 negative regulation of phosphatidylinositol biosynthetic process GO:0010512 9.55 PDGFB PDGFA
33 negative regulation of lipid storage GO:0010888 9.5 TNF IL6 CRP
34 vascular endothelial growth factor production GO:0010573 9.43 TNF IL6 IL1B
35 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.35 VEGFA TNF PDGFB PDGFA DCN
36 extracellular matrix organization GO:0030198 9.23 TNF SPP1 PDGFB PDGFA MMP3 MMP13

Molecular functions related to Tendinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.62 VEGFA PDGFB PDGFA IL6
2 extracellular matrix binding GO:0050840 9.43 VEGFA SPP1 DCN
3 cytokine activity GO:0005125 9.43 VEGFA TNF SPP1 IL6 IL1B CCL8
4 platelet-derived growth factor binding GO:0048407 9.4 PDGFB PDGFA
5 growth factor receptor binding GO:0070851 9.37 PDGFB PDGFA
6 platelet-derived growth factor receptor binding GO:0005161 9.33 VEGFA PDGFB PDGFA
7 collagen binding GO:0005518 9.02 PDGFB PDGFA MMP13 DCN COMP
Sources

Sources for Tendinitis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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