Aliases & Classifications for Tendinopathy

MalaCards integrated aliases for Tendinopathy:

Name: Tendinopathy 40 37 17 71

External Ids:

UMLS 71 C1568272

Summaries for Tendinopathy

MalaCards based summary : Tendinopathy is related to tendinosis and synovitis, and has symptoms including muscle weakness, myalgia and muscle cramp. An important gene associated with Tendinopathy is ENPP1 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 1), and among its related pathways/superpathways are Integrin Pathway and G-protein signaling Ras family GTPases in kinase cascades (scheme). The drugs Polidocanol and Etoricoxib have been mentioned in the context of this disorder. Affiliated tissues include testes, bone and spinal cord, and related phenotype is homeostasis/metabolism.

Wikipedia : 74 Tendinopathy, also known as tendinitis or tendonitis, is a type of tendon disorder that results in pain,... more...

Related Diseases for Tendinopathy

Diseases related to Tendinopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)
# Related Disease Score Top Affiliating Genes
1 tendinosis 32.7 MMP3 MMP1
2 synovitis 29.9 MMP8 MMP3 MMP1
3 clubfoot 29.0 COL5A1 CASP8 CASP3
4 tendinitis 12.4
5 tenosynovitis 11.6
6 cole disease 11.4
7 de quervain disease 11.3
8 rapidly involuting congenital hemangioma 10.9
9 epicondylitis 10.8
10 frozen shoulder 10.6
11 bursitis 10.6
12 fasciitis 10.5
13 plantar fasciitis 10.5
14 chronic pain 10.4
15 shoulder impingement syndrome 10.4
16 calcific tendinitis 10.4
17 exostosis 10.3
18 enthesopathy 10.3
19 osteoarthritis 10.3
20 plica syndrome 10.2
21 gout 10.2
22 periarthritis 10.2
23 diabetes mellitus 10.2
24 47,xyy 10.2
25 superior limbic keratoconjunctivitis 10.2 MMP3 MMP1
26 spastic entropion 10.1 MMP3 MMP1
27 androgen insensitivity, partial 10.1
28 body mass index quantitative trait locus 1 10.1
29 patellar tendinitis 10.1
30 arthropathy 10.1
31 spinal cord injury 10.1
32 conjunctivochalasis 10.1 MMP3 MMP1
33 periodontitis, chronic 10.1 MMP8 MMP1
34 epidermolysis bullosa dystrophica 10.1 MMP3 MMP1
35 corneal edema 10.1 MMP3 MMP1
36 periodontitis, aggressive, 1 10.1 MMP8 MMP1
37 gastroschisis 10.1 MMP3 MMP1
38 caspase 8 deficiency 10.1 COL5A1 CASP8
39 bone deterioration disease 10.1 MMP3 MMP1
40 viral meningitis 10.0 MMP3 MMP1
41 chronic ulcer of skin 10.0 MMP8 MMP1
42 spinal stenosis 10.0 MMP3 MMP1
43 carpal tunnel syndrome 10.0
44 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.0
45 spondylometaphyseal dysplasia, sedaghatian type 10.0
46 body mass index quantitative trait locus 11 10.0
47 arts syndrome 10.0
48 body mass index quantitative trait locus 9 10.0
49 body mass index quantitative trait locus 8 10.0
50 body mass index quantitative trait locus 4 10.0

Graphical network of the top 20 diseases related to Tendinopathy:



Diseases related to Tendinopathy

Symptoms & Phenotypes for Tendinopathy

UMLS symptoms related to Tendinopathy:


muscle weakness, myalgia, muscle cramp, muscle rigidity, muscle spasticity

MGI Mouse Phenotypes related to Tendinopathy:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.17 CASP3 CASP8 ENPP1 MMP1 MMP3 MMP8

Drugs & Therapeutics for Tendinopathy

Drugs for Tendinopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 163)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Polidocanol Approved Phase 4 9002-92-0
2
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
3
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
4
Etanercept Approved, Investigational Phase 4 185243-69-0
5
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
6
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
7
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
8
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
9 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
10
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
11
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
12
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
13
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
14
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
15 Sclerosing Solutions Phase 4
16 Cyclooxygenase 2 Inhibitors Phase 4
17 Methylprednisolone Acetate Phase 4
18 Respiratory System Agents Phase 4
19 Anti-Asthmatic Agents Phase 4
20 Antineoplastic Agents, Hormonal Phase 4
21 Antiemetics Phase 4
22 Gastrointestinal Agents Phase 4
23
Ibuprofen Approved Phase 3 15687-27-1 3672
24
Selenium Approved, Investigational, Vet_approved Phase 3 7782-49-2
25
Zinc Approved, Investigational Phase 3 7440-66-6 32051
26
Copper Approved, Investigational Phase 3 7440-50-8 27099
27
Ropivacaine Approved Phase 2, Phase 3 84057-95-4 71273 175805
28
Etodolac Approved, Investigational, Vet_approved Phase 3 41340-25-4 3308
29
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
30
Ofloxacin Approved Phase 3 82419-36-1 4583
31
Clonidine Approved Phase 3 4205-90-7 2803
32
Ketamine Approved, Vet_approved Phase 2, Phase 3 6740-88-1 3821
33
Glycolic acid Approved, Investigational Phase 3 79-14-1 757
34
Ketoprofen Approved, Vet_approved Phase 3 22071-15-4 3825
35
Manganese Approved, Nutraceutical Phase 3 7439-96-5 27854
36
Glutamic acid Approved, Nutraceutical Phase 2, Phase 3 56-86-0 33032
37
Cortisone Experimental Phase 3 53-06-5 222786
38 Copper Supplement Phase 3
39 Neurotransmitter Agents Phase 3
40 Adrenergic alpha-Agonists Phase 3
41 Vasoconstrictor Agents Phase 3
42 Adrenergic Agents Phase 3
43 Adrenergic Agonists Phase 3
44 Sympathomimetics Phase 3
45 Antihypertensive Agents Phase 3
46 Sympatholytics Phase 3
47 Cytochrome P-450 Enzyme Inhibitors Phase 3
48 Adrenergic beta-Agonists Phase 3
49 Bronchodilator Agents Phase 3
50 Mydriatics Phase 3

Interventional clinical trials:

(show top 50) (show all 314)
# Name Status NCT ID Phase Drugs
1 Insertional Achilles Tendinopathy: A Randomized Trial to Evaluate the Effectiveness of Transferring the Flexor Hallucis Longus Tendon Unknown status NCT01341509 Phase 4
2 Celestone Versus Ketorolac Injection for the Treatment of DeQuervains Tenosyovitis Unknown status NCT02604537 Phase 4 Celestone;Ketorolac
3 Functional Improvement and Ultrasound Tissue Characterisation of the Achilles Tendon Following Sodium Hyaluronate Injection for Plantaris Friction Syndrome Unknown status NCT03077009 Phase 4 Hyaluronic Acid
4 Placebo Controlled Trial, Testing the Efficacy of Polidocanol Injections as a Treatment of Chronic Achilles Tendinopathy. Completed NCT00377910 Phase 4 Aethoxysclerol
5 "NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes" Completed NCT00792376 Phase 4 etoricoxib;diclofenac
6 Shockwave Therapy of Chronic Achilles Tendinopathy. A Double-blind, Randomized Clinical Trial of Efficacy Completed NCT00958620 Phase 4
7 The Value of a High-Volume Image-Guided Injection in Chronic Midportion Achilles Tendinopathy: a Double-blind, Randomized, Placebo-controlled Clinical Trial Completed NCT02996409 Phase 4 HVIGI;LVIGI
8 The Value of Platelet-Rich Plasma in Chronic Midportion Achilles Tendinopathy: a Double-blind Randomized Clinical Trial Completed NCT00761423 Phase 4
9 Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to a Single Intrabursal Injection of Corticosteroids in Patients With Shoulder Calcific Tendinopathy Completed NCT01652495 Phase 4 methylprednisolone acetate;Triamcinolone Acetonide
10 Radiofrequency-based Plasma Microdebridement Compared to Surgical Microdebridement for Treating Achilles Tendinosis: A Prospective, Randomized, Controlled Multi-Center Study" Completed NCT00534781 Phase 4
11 Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection: A Double Blind Controlled Study Completed NCT02403856 Phase 4 Sodium Chloride 0.9%;Methylprednisolone acetate
12 Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer: A Prospective, Randomized, Controlled Trial Completed NCT00950053 Phase 4
13 A Prospective Study of the Use of the Madrid Ultrasound Scoring System in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With Spondyloarthritis Completed NCT02960035 Phase 4 50mg etanercept;25mg etanercept;placebo
14 A Single-blinded Randomized Controlled Trial Comparing Patients Who Receive a Corticosteroid Injection for Nontraumatic Degenerative Rotator Cuff Tears or Tendinopathy and Scheduled Use of a Dynamic Elastic Garment to Patients Who Receive a Corticosteroid Injection Alone. Recruiting NCT03032432 Phase 4 Corticosteroid injection
15 Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial Recruiting NCT04115644 Phase 4 Ketorolac;Marcaine (placebo);Kenalog
16 Achilles Tendinopathy Treated With Heavy Slow Resistance Training Supplemented With Injection of Glucocorticosteroid or Local Anaesthetic. Active, not recruiting NCT02580630 Phase 4 Ultrasound guided injection with Glucocorticosteroid;Ultrasound guided injection with local anaestethic
17 Comparison of Leukocyte-rich Platelet Rich Plasma Injection to Percutaneous Tenotomy in the Treatment of Chronic Common Extensor Tendinopathy Not yet recruiting NCT04384809 Phase 4
18 Calcific Tendonitis Treatment: Barbotage vs. Barbotage With Cortisone Injection: A Randomized Controlled Double-Blind Study Not yet recruiting NCT04126278 Phase 4 Barbotage;Dexamethasone
19 Efficacy Evaluation of Surgical Treatment Using Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis) Not yet recruiting NCT03718637 Phase 4
20 Comparative Effectiveness of Particulate Versus Nonparticulate Corticosteroid Injections for the Treatment of Musculoskeletal Conditions Not yet recruiting NCT04278833 Phase 4 Triamcinolone or Betamethasone;Dexamethasone
21 Ultrasound-Guided Platelet Rich Plasma Versus Whole Blood Injection for the Treatment of Gluteus Medius Tendinopathy: A Double-Blind Randomized Controlled Study Terminated NCT02978833 Phase 4
22 A Prospective Clinical Trial Comparing the Efficacy of Brisement to Physical Therapy for the Treatment of Achilles Tendinosis Withdrawn NCT03363789 Phase 4
23 A Randomized Single Blinded Prospective Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients Withdrawn NCT03319784 Phase 4 Ketorolac;Triamcinolone Acetonide
24 "Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis" Withdrawn NCT00420875 Phase 4
25 Treatment for Achilles Tendinopathy Unknown status NCT00835939 Phase 2, Phase 3 25% Dextrose and 1% Lidocaine;Lidocaine
26 Eccentric Training With Our Without Elbow Brace for Epicondylitis - a Randomized Clinical Trial Unknown status NCT01273688 Phase 3
27 Vibration Training in Epicondylitis - a Randomized Trial Unknown status NCT01269879 Phase 3
28 Treatment of Subacromial Shoulder Pain Unknown status NCT01441830 Phase 3
29 Multicenter, Randomized, Double-blind Trial to Evaluate the Efficacy and Safety Aliviador Compared to Gelol in the Relief in Patients With Contusons, Sprains,Trauma and Muscle Injury. Unknown status NCT01097798 Phase 3 Aliviador;Gelol
30 Clinical Multicenter, Phase III, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Ibuprofen 50mg/g Gel in the Treatment of Patients With Muscle Pain, Joint, or Pain Caused by Sprains, Contusions, Tendinitis, or Myofascial Compared to Profenid ® 25mg/g. Gel Unknown status NCT01373697 Phase 3 Ibuprofen;Profenid
31 Clinical Multicenter Study, Randomized, Open, to Evaluate the Efficacy and Safety of Salonsip Compared to Sabiá Plaster Relief of the Signs and Symptoms in Patients With Contusions, Sprains, Injuries and Muscular Injuries With Less Than 24 Hours Early or Holders of Myalgia, Pain and Tendonitis in Regions Miofasciais Articulated. Unknown status NCT00970658 Phase 3 Salonsip plaster;Sabia plaster
32 A Randomized Clinical Trial Comparing the Effectiveness of Subacromial Decompression (Acromioplasty) Versus Subacromial Bursectomy (no Acromioplasty) in the Arthroscopic Treatment of Patients With Rotator Cuff Tendinosis Unknown status NCT00196573 Phase 3
33 Epidemiology of Incidents and Accidents in Sport. Influence of Moisture. Unknown status NCT02346786 Phase 3
34 The Value of Autologous Tenocyte Implantation in Patients With Chronic Achilles Tendinopathy: a Double-blind Randomised Clinical Trial Completed NCT01343836 Phase 2, Phase 3
35 Role of Biological Therapy in Rotator Cuff Tendinopathy. Effectiveness of Plasma Rich in Growth Factors Regarding Functional Capacity and Pain Compared With the Conventional Treatment Using Steroids Completed NCT01915979 Phase 3 Celestone cronodose (Bethametasone)
36 Impact of Peripheral Pain Perception on Central Sensitization and Movement Strategies in Patients With Chronic Achilles Tendinopathy Completed NCT03316378 Phase 2, Phase 3 Ropivacaine injection
37 A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Diclofenac Sodium Patch for the Topical Treatment of Pain Due to Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3 diclofenac sodium;Matching Placebo
38 A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder Completed NCT01161615 Phase 3 MRX-7EAT;Placebo
39 A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Topical Patch in the Treatment of Pain Due to Recent Onset Supraspinatous and/or Subacromial Tendonitis/Bursitis and/or Subdeltoid Bursitis of Shoulder Completed NCT01506154 Phase 3 MRX-7EAT
40 Pilot Randomized Controlled Trial to Evaluate Safety and Efficacy of Percutaneous Needle Tenotomy With Platelet Rich Plasma (Leukocyte Depleted)in Epicondylitis Completed NCT01945528 Phase 3 US-guided tenotomy with PRP;US-guided tenotomy with lidocaine
41 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase III Study of the Efficacy, Tolerability and Safety of Ketoprofen Topical Patch, 20% (KTP) in the Treatment of Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee Completed NCT00352625 Phase 3 Ketoprofen Topical Patch 20%
42 A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT) Completed NCT01371656 Phase 3 levofloxacin
43 Analgesic Benefit of PECS Blocks for Biceps Tenodesis Shoulder Surgery Completed NCT02741713 Phase 3 Solution for Injection in Interscalene Block;Solution for Injection in Sham Block;Solution for Injection PECS Blocks
44 Does Subacromial Injection With Glutamate Receptor (NMDAR) Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy? Recruiting NCT02967640 Phase 2, Phase 3 Ketalar;NaCl 9%
45 A Phase 3, Prospective, Double-Blinded, Randomized Controlled Trial Of The Micronized dHACM Injection As Compared To Saline Placebo Injection In The Treatment Of Achilles Tendonitis Recruiting NCT03414255 Phase 3 Saline Injection
46 Evaluation of Regenerative Medicine Treatment Outcomes With Amniotic Fluid for Musculoskeletal Conditions Recruiting NCT03390920 Phase 2, Phase 3
47 The Effect of Multiple Injection of Platlet-rich Plasma in Chronic Patellar Tendinopathy Not yet recruiting NCT03986372 Phase 2, Phase 3
48 Use of Extended Release Triamcinolone in the Treatment of Rotator Cuff Disease Suspended NCT04094298 Phase 3 FX006 Injection
49 A Randomised Double Blind Controlled Trial of Injection of Local Anaesthetic and Corticosteroid Under Ultrasound Control in the Greater Trochanteric Pain Syndrome. Terminated NCT01807962 Phase 3 rapidocain and bethametsaone;sterile saline
50 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase III Study of the Efficacy, Tolerability and Safety of Ketoprofen Topical Patch, 20% (KTP) in the Treatment of Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee Terminated NCT00426985 Phase 3 Ketoprofen Topical Patch 20%

Search NIH Clinical Center for Tendinopathy

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tendinopathy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tendinopathy:
Autologous tenocyte implantation for damaged tendons
Embryonic/Adult Cultured Cells Related to Tendinopathy:
Tenocytes PMIDs: 23314880 24068695

Genetic Tests for Tendinopathy

Anatomical Context for Tendinopathy

MalaCards organs/tissues related to Tendinopathy:

40
Testes, Bone, Spinal Cord, Bone Marrow, Whole Blood, Endothelial, Pituitary

Publications for Tendinopathy

Articles related to Tendinopathy:

(show top 50) (show all 3575)
# Title Authors PMID Year
1
Therapeutic tape use for lateral elbow tendinopathy: A survey of Australian healthcare practitioners. 61
32560866 2020
2
The use of PRP in treatment of Achilles Tendinopathy: A systematic review of literature. Study design: Systematic review of literature. 61
32566217 2020
3
Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: Is Platelet-Rich Plasma Injection More Effective Than Corticosteroid for Treatment of Gluteal Tendinopathy? 61
31361618 2020
4
Patellar tendinopathy outcome predictors in jumping athletes: feasibility of measures for a cohort study. 61
32460219 2020
5
Factors associated with positive outcomes of platelet-rich plasma therapy in Achilles tendinopathy. 61
32112184 2020
6
Efficacy of ultrasound-guided percutaneous treatment of the rotator cuff calcific tendinopathy with double needle technique. 61
32025148 2020
7
Dynamic ultrasound-guided trochanteric bursal injection. 61
32232500 2020
8
Ultrasound Definitions and Findings in Greater Trochanteric Pain Syndrome: A Systematic Review. 61
32381380 2020
9
Tendon response to matrix unloading is determined by the patho-physiological niche. 61
31917255 2020
10
Grip strength is more sensitive to changes in elbow position than isolated wrist extension strength in patients with lateral elbow tendinopathy. 61
32565100 2020
11
Which treatment is most effective for patients with Achilles tendinopathy? A living systematic review with network meta-analysis of 29 randomised controlled trials. 61
32522732 2020
12
Adipose-derived stem cells improve tendon repair and prevent ectopic ossification in tendinopathy by inhibiting inflammation and inducing neovascularization in the early stage of tendon healing. 61
31989000 2020
13
Qualitative and quantitative analysis of glenoid bone stock and glenoid version: inter-reader analysis and correlation with rotator cuff tendinopathy and atrophy in patients with shoulder osteoarthritis. 61
31955231 2020
14
The association of working alliance, outcome expectation, adherence and self-efficacy with clinical outcomes for Achilles tendinopathy: A feasibility cohort study (the MAP study). 61
31997555 2020
15
Conservative management of De Quervain's tendinopathy with an orthopedic manual physical therapy approach emphasizing first CMC manipulation: a retrospective case series. 61
32478626 2020
16
Local Anesthetic Injection Resolves Movement Pain, Motor Dysfunction, and Pain Catastrophizing in Individuals With Chronic Achilles Tendinopathy: A Nonrandomized Clinical Trial. 61
32349638 2020
17
The effect of psychological factors on pain, function and quality of life in patients with rotator cuff tendinopathy: A systematic review. 61
32452391 2020
18
Evaluating the immediate effect of forearm and wrist orthoses on pain and function in individuals with lateral elbow tendinopathy: A systematic review. 61
32452393 2020
19
Correction to: Qualitative and quantitative analysis of glenoid bone stock and glenoid version: inter-reader analysis and correlation with rotator cuff tendinopathy and atrophy in patients with shoulder osteoarthritis. 61
32086541 2020
20
Response to "Letter Regarding: Effectiveness of Extracorporeal Shockwave Therapy in the Treatment of Chronic Insertional Achilles Tendinopathy". 61
32538195 2020
21
Discriminative and convergent validity of strain elastography for detecting tendinopathy within the supraspinatus tendon: a cross-sectional study. 61
32490419 2020
22
The association between patellar tendon stiffness measured with shear-wave elastography and patellar tendinopathy-a case-control study. 61
32500197 2020
23
Correction to: Application of shear wave elastography and B-mode ultrasound in patellar tendinopathy after extracorporeal shockwave therapy. 61
32524318 2020
24
The effect of injection volume on long-term outcomes of US-guided subacromial bursa injections. 61
32540584 2020
25
Uremic Toxins and Ciprofloxacin Affect Human Tenocytes In Vitro. 61
32545914 2020
26
Effects of iliotibial band syndrome on pain sensitivity and gait kinematics in female runners: A preliminary study. 61
32388078 2020
27
Relationship Between Jump-Landing Kinematics and Lower Extremity Overuse Injuries in Physically Active Populations: A Systematic Review and Meta-Analysis. 61
32514700 2020
28
Prevalence of lateral epicondylosis in veteran manual wheelchair users participating in adaptive sports. 61
32527209 2020
29
Injection Techniques for Common Chronic Pain Conditions of the Foot: A Comprehensive Review. 61
32107725 2020
30
Clinical Value of Ultrasonographic Assessment in Lateral Epicondylitis Versus Asymptomatic Healthy Controls. 61
32484714 2020
31
Evaluation of Postoperative Changes in Patellar and Quadriceps Tendons after Total Knee Arthroplasty-A Comprehensive Analysis by Shear Wave Elastography, Power Doppler and B-mode Ultrasound. 61
31526688 2020
32
Achilles tendoscopy for non insertional Achilles tendinopathy. A case series study. 61
31196696 2020
33
Distalising tibial tubercle osteotomy decreases patellar tendon force - A treatment rationale for recalcitrant patellar tendinopathy. 61
32220536 2020
34
Letter Regarding: Effectiveness of Extracorporeal Shockwave Therapy in the Treatment of Chronic Insertional Achilles Tendinopathy. 61
32538197 2020
35
Effectiveness of Percutaneous Electrolysis in Supraspinatus Tendinopathy: A Single-Blinded Randomized Controlled Trial. 61
32545583 2020
36
No Indications for Subacromial Decompression in Rotator Cuff Tendinopathy: A Level I Evidence Clinical Guideline. 61
32503763 2020
37
Surgical treatment for long head of the biceps tendinopathy: a network meta-analysis. 61
32037231 2020
38
ICON PART-T 2019-International Scientific Tendinopathy Symposium Consensus: recommended standards for reporting participant characteristics in tendinopathy research (PART-T). 61
31519545 2020
39
Suprapectoral versus subpectoral tenodesis for Long Head Biceps Brachii tendinopathy: A systematic review and meta-analysis. 61
32461094 2020
40
Taping, Bracing, and Injection Treatment for Patellofemoral Pain and Patellar Tendinopathy. 61
32500350 2020
41
Advances in the development of gene therapy, noncoding RNA, and exosome-based treatments for tendinopathy. 61
32501571 2020
42
Photobiomodulation with low-level laser therapy for treating Achilles tendinopathy: a systematic review and meta-analysis. 61
32204620 2020
43
Physiotherapists deliver management broadly consistent with recommended practice in rotator cuff tendinopathy: An observational study. 61
32148327 2020
44
Role of Mechanical Loading for Platelet-Rich Plasma-Treated Achilles Tendinopathy. 61
32516191 2020
45
Operative Treatment is Not Associated with More Relief of Depression Symptoms than Nonoperative Treatment in Patients with Common Hand Illness. 61
32097128 2020
46
Meta-analysis of Noninsertional Achilles Tendinopathy. 61
32349544 2020
47
Clinical management of tendinopathy: A systematic review of systematic reviews evaluating the effectiveness of tendinopathy treatments. 61
32484976 2020
48
Ultrasound-Guided Electrocoagulation of Neovessels for Chronic Patellar Tendinopathy. 61
32577355 2020
49
Current pharmacological approaches to the treatment of tendinopathy. 61
32511031 2020
50
Hip abductor tendon tears: where are we now? 61
32513090 2020

Variations for Tendinopathy

Expression for Tendinopathy

Search GEO for disease gene expression data for Tendinopathy.

Pathways for Tendinopathy

Pathways related to Tendinopathy according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.99 VCAN MMP8 MMP3 MMP1 COL5A1 CASP3
2
Show member pathways
11.97 MMP3 MMP1 CASP3
3
Show member pathways
11.89 MMP3 MMP1 CASP8 CASP3
4 11.82 MMP1 CASP8 CASP3
5
Show member pathways
11.75 VCAN MMP8 MMP3 MMP1 COL5A1 CASP3
6 11.66 MMP3 CASP8 CASP3
7
Show member pathways
11.58 MMP8 MMP3 MMP1
8
Show member pathways
11.35 MMP3 MMP1
9 11.29 CASP8 CASP3
10 11.28 VCAN MMP3 MMP1
11
Show member pathways
11.25 CASP8 CASP3
12 11.22 MMP1 CASP3
13 11.17 CASP8 CASP3
14 10.99 MMP1 CASP8 CASP3
15 10.72 VCAN MMP3 MMP1

GO Terms for Tendinopathy

Cellular components related to Tendinopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.65 VCAN MMP8 MMP3 ENPP1 COL5A1
2 extracellular region GO:0005576 9.63 VCAN MMP8 MMP3 MMP1 ENPP1 COL5A1
3 collagen-containing extracellular matrix GO:0062023 9.5 VCAN MMP8 COL5A1
4 extracellular matrix GO:0031012 9.02 VCAN MMP8 MMP3 MMP1 COL5A1
5 death-inducing signaling complex GO:0031264 8.96 CASP8 CASP3

Biological processes related to Tendinopathy according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.65 MMP3 MMP1 CASP3
2 proteolysis GO:0006508 9.55 MMP8 MMP3 MMP1 CASP8 CASP3
3 positive regulation of protein complex assembly GO:0031334 9.49 MMP3 MMP1
4 response to tumor necrosis factor GO:0034612 9.46 CASP8 CASP3
5 response to antibiotic GO:0046677 9.43 CASP8 CASP3
6 extracellular matrix disassembly GO:0022617 9.43 MMP8 MMP3 MMP1
7 execution phase of apoptosis GO:0097194 9.4 CASP8 CASP3
8 regulation of neuroinflammatory response GO:0150077 9.37 MMP8 MMP3
9 response to cobalt ion GO:0032025 9.32 CASP8 CASP3
10 collagen catabolic process GO:0030574 9.13 MMP8 MMP3 MMP1
11 extracellular matrix organization GO:0030198 9.02 VCAN MMP8 MMP3 MMP1 COL5A1

Molecular functions related to Tendinopathy according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 9.8 MMP8 MMP3 MMP1 ENPP1
2 serine-type endopeptidase activity GO:0004252 9.65 MMP8 MMP3 MMP1
3 metallopeptidase activity GO:0008237 9.63 MMP8 MMP3 MMP1
4 death receptor binding GO:0005123 9.43 CASP8 CASP3
5 metalloendopeptidase activity GO:0004222 9.43 MMP8 MMP3 MMP1
6 hydrolase activity GO:0016787 9.43 MMP8 MMP3 MMP1 ENPP1 CASP8 CASP3
7 cysteine-type endopeptidase activity involved in apoptotic process GO:0097153 9.4 CASP8 CASP3
8 cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0097200 9.37 CASP8 CASP3
9 endopeptidase activity GO:0004175 9.33 MMP8 MMP3 MMP1
10 cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097199 9.32 CASP8 CASP3
11 peptidase activity GO:0008233 9.02 MMP8 MMP3 MMP1 CASP8 CASP3

Sources for Tendinopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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