Aliases & Classifications for Tendinopathy

MalaCards integrated aliases for Tendinopathy:

Name: Tendinopathy 41 38 17 72

External Ids:

UMLS 72 C1568272

Summaries for Tendinopathy

MalaCards based summary : Tendinopathy is related to tendinitis and tendinosis, and has symptoms including muscle weakness, myalgia and muscle cramp. An important gene associated with Tendinopathy is ENPP1 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 1), and among its related pathways/superpathways are Integrin Pathway and IL-17 Family Signaling Pathways. The drugs Polidocanol and Diclofenac have been mentioned in the context of this disorder. Affiliated tissues include testes, bone and spinal cord.

Wikipedia : 75 Tendinopathy, also known as tendinitis or tendonitis, is a type of tendon disorder that results in pain,... more...

Related Diseases for Tendinopathy

Diseases related to Tendinopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 tendinitis 12.3
2 tendinosis 11.7
3 tenosynovitis 11.6
4 cole disease 11.4
5 de quervain disease 11.3
6 rapidly involuting congenital hemangioma 10.9
7 epicondylitis 10.8
8 fasciitis 10.5
9 frozen shoulder 10.5
10 bursitis 10.5
11 plantar fasciitis 10.5
12 chronic pain 10.4
13 calcific tendinitis 10.4
14 shoulder impingement syndrome 10.4
15 enthesopathy 10.3
16 osteoarthritis 10.3
17 periodontitis, chronic 10.2 MMP8 MMP1
18 synovitis 10.2
19 periarthritis 10.2
20 chronic ulcer of skin 10.2 MMP8 MMP1
21 exostosis 10.2
22 diabetes mellitus 10.2
23 pelvic organ prolapse 10.2 MMP8 MMP1
24 gingival disease 10.1 MMP8 MMP1
25 odontogenic myxoma 10.1 VCAN MMP1
26 vitreoretinal dystrophy 10.1 VCAN MMP8
27 preterm premature rupture of the membranes 10.1 MMP8 MMP1
28 androgen insensitivity, partial 10.1
29 body mass index quantitative trait locus 1 10.1
30 patellar tendinitis 10.1
31 gout 10.1
32 47,xyy 10.1
33 aortic aneurysm, familial abdominal, 1 10.1 MMP8 MMP1
34 pulmonary emphysema 10.1 MMP8 MMP1
35 carpal tunnel syndrome 10.0
36 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.0
37 body mass index quantitative trait locus 11 10.0
38 arts syndrome 10.0
39 body mass index quantitative trait locus 9 10.0
40 body mass index quantitative trait locus 8 10.0
41 body mass index quantitative trait locus 4 10.0
42 body mass index quantitative trait locus 10 10.0
43 body mass index quantitative trait locus 7 10.0
44 body mass index quantitative trait locus 12 10.0
45 body mass index quantitative trait locus 14 10.0
46 body mass index quantitative trait locus 18 10.0
47 hydrops, lactic acidosis, and sideroblastic anemia 10.0
48 body mass index quantitative trait locus 19 10.0
49 body mass index quantitative trait locus 20 10.0
50 hyperparathyroidism 10.0

Graphical network of the top 20 diseases related to Tendinopathy:

Diseases related to Tendinopathy

Symptoms & Phenotypes for Tendinopathy

UMLS symptoms related to Tendinopathy:

muscle weakness, myalgia, muscle cramp, muscle rigidity, muscle spasticity

Drugs & Therapeutics for Tendinopathy

Drugs for Tendinopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 166)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Polidocanol Approved Phase 4 9002-92-0
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
Etanercept Approved, Investigational Phase 4 185243-69-0
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
6 Sclerosing Solutions Phase 4
7 Adjuvants, Immunologic Phase 4
8 Viscosupplements Phase 4
Zinc Approved, Investigational Phase 3 7440-66-6 32051
Ibuprofen Approved Phase 3 15687-27-1 3672
Selenium Approved, Investigational, Vet_approved Phase 3 7782-49-2
Copper Approved, Investigational Phase 3 7440-50-8 27099
Etodolac Approved, Investigational, Vet_approved Phase 3 41340-25-4 3308
Ofloxacin Approved Phase 3 82419-36-1 4583
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
Clonidine Approved Phase 3 4205-90-7 2803
Ketamine Approved, Vet_approved Phase 2, Phase 3 6740-88-1 3821
Betamethasone Approved, Vet_approved Phase 3 378-44-9 9782
Ketoprofen Approved, Vet_approved Phase 3 22071-15-4 3825
Manganese Approved, Nutraceutical Phase 3 7439-96-5 27854
Glutamic acid Approved, Nutraceutical Phase 2, Phase 3 56-86-0 33032
Cortisone Experimental Phase 3 53-06-5 222786
23 Anti-Bacterial Agents Phase 3
24 Anti-Infective Agents Phase 3
25 Cytochrome P-450 Enzyme Inhibitors Phase 3
26 Renal Agents Phase 3
27 Topoisomerase Inhibitors Phase 3
28 Anti-Infective Agents, Urinary Phase 3
29 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
30 Adrenergic alpha-2 Receptor Agonists Phase 3
31 Antihypertensive Agents Phase 3
32 Sympatholytics Phase 3
33 Mitogens Phase 2, Phase 3
34 Excitatory Amino Acid Antagonists Phase 2, Phase 3
35 Anesthetics, General Phase 2, Phase 3
36 Anesthetics, Dissociative Phase 2, Phase 3
37 Excitatory Amino Acids Phase 2, Phase 3
38 Anesthetics, Intravenous Phase 2, Phase 3
39 Betamethasone-17,21-dipropionate Phase 3
40 Betamethasone sodium phosphate Phase 3
41 Betamethasone Valerate Phase 3 2152-44-5
42 Betamethasone benzoate Phase 3
43 Betamethasone dipropionate, betamethasone sodium phosphate drug combination Phase 3
Nitric Oxide Approved Phase 2 10102-43-9 145068
Tetracaine Approved, Vet_approved Phase 2 94-24-6 5411
Acetylcholine Approved, Investigational Phase 2 51-84-3 187
Acetaminophen Approved Phase 2 103-90-2 1983
tannic acid Approved Phase 2 1401-55-4
Benzocaine Approved, Investigational Phase 2 94-09-7, 1994-09-7 2337
50 Antidotes Phase 2

Interventional clinical trials:

(show top 50) (show all 273)
# Name Status NCT ID Phase Drugs
1 Insertional Achilles Tendinopathy: A Randomized Trial to Evaluate the Effectiveness of Transferring the Flexor Hallucis Longus Tendon Unknown status NCT01341509 Phase 4
2 Celestone Versus Ketorolac Injection for the Treatment of DeQuervains Tenosyovitis Unknown status NCT02604537 Phase 4 Celestone;Ketorolac
3 Placebo Controlled Trial, Testing the Efficacy of Polidocanol Injections as a Treatment of Chronic Achilles Tendinopathy. Completed NCT00377910 Phase 4 Aethoxysclerol
4 "NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes" Completed NCT00792376 Phase 4 etoricoxib;diclofenac
5 Shockwave Therapy of Chronic Achilles Tendinopathy. A Double-blind, Randomized Clinical Trial of Efficacy Completed NCT00958620 Phase 4
6 The Value of a High-Volume Image-Guided Injection in Chronic Midportion Achilles Tendinopathy: a Double-blind, Randomized, Placebo-controlled Clinical Trial Completed NCT02996409 Phase 4 HVIGI;LVIGI
7 The Value of Platelet-Rich Plasma in Chronic Midportion Achilles Tendinopathy: a Double-blind Randomized Clinical Trial Completed NCT00761423 Phase 4
8 Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to a Single Intrabursal Injection of Corticosteroids in Patients With Shoulder Calcific Tendinopathy Completed NCT01652495 Phase 4 methylprednisolone acetate;Triamcinolone Acetonide
9 Radiofrequency-based Plasma Microdebridement Compared to Surgical Microdebridement for Treating Achilles Tendinosis: A Prospective, Randomized, Controlled Multi-Center Study" Completed NCT00534781 Phase 4
10 Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection: A Double Blind Controlled Study Completed NCT02403856 Phase 4 Sodium Chloride 0.9%;Methylprednisolone acetate
11 Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer: A Prospective, Randomized, Controlled Trial Completed NCT00950053 Phase 4
12 A Prospective Study of the Use of the Madrid Ultrasound Scoring System in the Treatment of Anti-TNF Blocker to Peripheral Tendonitis in Patients With Spondyloarthritis Completed NCT02960035 Phase 4 etanercept;etanercept (half dose);placebo
13 A Single-blinded Randomized Controlled Trial Comparing Patients Who Receive a Corticosteroid Injection for Nontraumatic Degenerative Rotator Cuff Tears or Tendinopathy and Scheduled Use of a Dynamic Elastic Garment to Patients Who Receive a Corticosteroid Injection Alone. Recruiting NCT03032432 Phase 4 Corticosteroid injection
14 Achilles Tendinopathy Treated With Heavy Slow Resistance Training Supplemented With Injection of Glucocorticosteroid or Local Anaesthetic. Recruiting NCT02580630 Phase 4 Ultrasound guided injection with Glucocorticosteroid;Ultrasound guided injection with local anaestethic
15 Functional Improvement and Ultrasound Tissue Characterisation of the Achilles Tendon Following Sodium Hyaluronate Injection for Plantaris Friction Syndrome Recruiting NCT03077009 Phase 4 Hyaluronic Acid
16 Efficacy Evaluation of Surgical Treatment Using Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis) Not yet recruiting NCT03718637 Phase 4
17 Ultrasound-Guided Platelet Rich Plasma Versus Whole Blood Injection for the Treatment of Gluteus Medius Tendinopathy: A Double-Blind Randomized Controlled Study Terminated NCT02978833 Phase 4
18 A Prospective Clinical Trial Comparing the Efficacy of Brisement to Physical Therapy for the Treatment of Achilles Tendinosis Withdrawn NCT03363789 Phase 4
19 A Randomized Single Blinded Prospective Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients Withdrawn NCT03319784 Phase 4 Ketorolac;Triamcinolone Acetonide
20 "Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis" Withdrawn NCT00420875 Phase 4
21 Treatment for Achilles Tendinopathy Unknown status NCT00835939 Phase 2, Phase 3 25% Dextrose and 1% Lidocaine;Lidocaine
22 Eccentric Training With Our Without Elbow Brace for Epicondylitis - a Randomized Clinical Trial Unknown status NCT01273688 Phase 3
23 Vibration Training in Epicondylitis - a Randomized Trial Unknown status NCT01269879 Phase 3
24 Treatment of Subacromial Shoulder Pain Unknown status NCT01441830 Phase 3
25 Multicenter, Randomized, Double-blind Trial to Evaluate the Efficacy and Safety Aliviador Compared to Gelol in the Relief in Patients With Contusons, Sprains,Trauma and Muscle Injury. Unknown status NCT01097798 Phase 3 Aliviador;Gelol
26 Clinical Multicenter, Phase III, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Ibuprofen 50mg/g Gel in the Treatment of Patients With Muscle Pain, Joint, or Pain Caused by Sprains, Contusions, Tendinitis, or Myofascial Compared to Profenid ® 25mg/g. Gel Unknown status NCT01373697 Phase 3 Ibuprofen;Profenid
27 Clinical Multicenter Study, Randomized, Open, to Evaluate the Efficacy and Safety of Salonsip Compared to Sabiá Plaster Relief of the Signs and Symptoms in Patients With Contusions, Sprains, Injuries and Muscular Injuries With Less Than 24 Hours Early or Holders of Myalgia, Pain and Tendonitis in Regions Miofasciais Articulated. Unknown status NCT00970658 Phase 3 Salonsip plaster;Sabia plaster
28 Epidemiology of Incidents and Accidents in Sport. Influence of Moisture. Unknown status NCT02346786 Phase 3
29 A Randomized Clinical Trial Comparing the Effectiveness of Subacromial Decompression (Acromioplasty) Versus Subacromial Bursectomy (no Acromioplasty) in the Arthroscopic Treatment of Patients With Rotator Cuff Tendinosis Unknown status NCT00196573 Phase 3
30 The Value of Autologous Tenocyte Implantation in Patients With Chronic Achilles Tendinopathy: a Double-blind Randomised Clinical Trial Completed NCT01343836 Phase 2, Phase 3
31 Impact of Peripheral Pain Perception on Central Sensitization and Movement Strategies in Patients With Chronic Achilles Tendinopathy Completed NCT03316378 Phase 2, Phase 3 Ropivacaine injection
32 Role of Biological Therapy in Rotator Cuff Tendinopathy. Effectiveness of Plasma Rich in Growth Factors Regarding Functional Capacity and Pain Compared With the Conventional Treatment Using Steroids Completed NCT01915979 Phase 3 Celestone cronodose (Bethametasone)
33 A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Diclofenac Sodium Patch for the Topical Treatment of Pain Due to Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3 diclofenac sodium;Matching Placebo
34 A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Topical Patch in the Treatment of Pain Due to Recent Onset Supraspinatous and/or Subacromial Tendonitis/Bursitis and/or Subdeltoid Bursitis of Shoulder Completed NCT01506154 Phase 3 MRX-7EAT
35 A Randomized, Multi-Center, Double-Blind, Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder Completed NCT01161615 Phase 3 MRX-7EAT;Placebo
36 Pilot Randomized Controlled Trial to Evaluate Safety and Efficacy of Percutaneous Needle Tenotomy With Platelet Rich Plasma (Leukocyte Depleted)in Epicondylitis Completed NCT01945528 Phase 3 US-guided tenotomy with PRP;US-guided tenotomy with lidocaine
37 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase III Study of the Efficacy, Tolerability and Safety of Ketoprofen Topical Patch, 20% (KTP) in the Treatment of Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee Completed NCT00352625 Phase 3 Ketoprofen Topical Patch 20%
38 A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT) Completed NCT01371656 Phase 3 levofloxacin
39 Analgesic Benefit of PECS Blocks for Biceps Tenodesis Shoulder Surgery Completed NCT02741713 Phase 3 Solution for Injection in Interscalene Block;Solution for Injection in Sham Block;Solution for Injection PECS Blocks
40 Does Subacromial Injection With Glutamate Receptor (NMDAR) Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy? Recruiting NCT02967640 Phase 2, Phase 3 Ketalar;NaCl 9%
41 A Phase 3, Prospective, Double-Blinded, Randomized Controlled Trial Of The Micronized dHACM Injection As Compared To Saline Placebo Injection In The Treatment Of Achilles Tendonitis Recruiting NCT03414255 Phase 3 Saline Injection
42 Glenohumeral Re-centering During Closed Kinetic Chain for Shoulder Physiotherapy. A Prospective and Randomized Study. Recruiting NCT02874105 Phase 3
43 Evaluation of Regenerative Medicine Treatment Outcomes With Amniotic Fluid for Musculoskeletal Conditions Recruiting NCT03390920 Phase 2, Phase 3
44 The Effect of Multiple Injection of Platlet-rich Plasma in Chronic Patellar Tendinopathy Not yet recruiting NCT03986372 Phase 2, Phase 3
45 A Randomised Double Blind Controlled Trial of Injection of Local Anaesthetic and Corticosteroid Under Ultrasound Control in the Greater Trochanteric Pain Syndrome. Terminated NCT01807962 Phase 3 rapidocain and bethametsaone;sterile saline
46 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase III Study of the Efficacy, Tolerability and Safety of Ketoprofen Topical Patch, 20% (KTP) in the Treatment of Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee Terminated NCT00426985 Phase 3 Ketoprofen Topical Patch 20%
47 Medial-Wedge Insole is Highly Effective in the Treatment of Valgus Knee Osteoarthritis Terminated NCT00467337 Phase 3
48 Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block Withdrawn NCT01538459 Phase 3 Dexamethasone;Bupivacaine
49 Study of the Treatment of Tendinopathy Unruptured of Rotator Cuff by Intramuscular Injection of Botulinum Toxin Unknown status NCT02867787 Phase 2 Botox arm
50 TENDOSHOCK-2010 - Combined Sclerosing Therapy, Extracorporeal Shockwave Therapy, Eccentric Training and Topical Glyceryl Trinitrate for Athletic Tendinopathies Unknown status NCT01185951 Phase 2 Polidocanol;Topical NO

Search NIH Clinical Center for Tendinopathy

Cell-based therapeutics:

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tendinopathy cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Tendinopathy:
Autologous tenocyte implantation for damaged tendons
Embryonic/Adult Cultured Cells Related to Tendinopathy:
Tenocytes PMIDs: 23314880 24068695

Genetic Tests for Tendinopathy

Anatomical Context for Tendinopathy

MalaCards organs/tissues related to Tendinopathy:

Testes, Bone, Spinal Cord, Bone Marrow, Whole Blood, Endothelial, Pituitary

Publications for Tendinopathy

Articles related to Tendinopathy:

(show top 50) (show all 3249)
# Title Authors PMID Year
Responsiveness of the Victorian Institute for Sport Assessment for Gluteal Tendinopathy (VISA-G), modified Harris hip and Oxford hip scores in patients undergoing hip abductor tendon repair. 38
31129382 2019
Do features of central sensitisation exist in Greater Trochanteric Pain Syndrome (GTPS)? A case control study. 38
31153026 2019
Physical findings differ between individuals with greater trochanteric pain syndrome and healthy controls: A systematic review with meta-analysis. 38
31369906 2019
Controlled-release curcumin attenuates progression of tendon ectopic calcification by regulating the differentiation of tendon stem/progenitor cells. 38
31349489 2019
Nonsurgical Treatment Options for Insertional Achilles Tendinopathy. 38
31371000 2019
Surgical Strategies for the Treatment of Insertional Achilles Tendinopathy. 38
31371002 2019
Minimally Invasive and Endoscopic Approach for the Treatment of Noninsertional Achilles Tendinopathy. 38
31370999 2019
Interfascicular matrix-mediated transverse deformation and sliding of discontinuous tendon subcomponents control the viscoelasticity and failure of tendons. 38
31132660 2019
Minimally Invasive and Endoscopic Treatment of Haglund Syndrome. 38
31371001 2019
Overuse Injuries of the Elbow. 38
31351542 2019
Anatomical and Functional Considerations in Achilles Tendon Lesions. 38
31370991 2019
Ultrasound Appearance of the Migration of Tendon Calcifications. 38
30653700 2019
Biologics in the Treatment of Achilles Tendon Pathologies. 38
31370998 2019
Efficacy of heavy eccentric calf training for treating mid-portion Achilles tendinopathy: a systematic review and meta-analysis. 38
30636702 2019
Letter to the editor re: The value of sonoelastography in the diagnosis of supraspinatus tendinopathy-a comparison study. 38
31298563 2019
A potential factor in the pathophysiology of lateral epicondylitis: The long sarcomere length of the extensor carpi radialis brevis muscle and implications for physiotherapy. 38
31383324 2019
N-acetylcysteine reduces glutamate-induced cytotoxicity to fibroblasts of rat supraspinatus tendons. 38
30755039 2019
Extracorporeal Shock Wave Therapy Immediately Affects Achilles Tendon Structure and Widespread Pressure Pain Thresholds in Healthy People: A Repeated-Measures Observational Study. 38
31021822 2019
Ultrasound-Guided Dry Needling of the Healthy Rat Supraspinatus Tendon Elicits Early Healing Without Causing Permanent Damage. 38
31042318 2019
Comparative assessment of hypothalamic-pituitary-adrenal axis suppression secondary to intrabursal injection of different glucocorticoids: a pilot study. 38
30877658 2019
Effect of Shoe and Surface Stiffness on Lower Limb Tendon Strain in Jumping. 38
30973480 2019
Alternative splicing induces cytoplasmic localization of RBFOX2 protein in calcific tendinopathy. 38
31128090 2019
Unsupervised Isometric Exercise versus Wait-and-See for Lateral Elbow Tendinopathy. 38
31425384 2019
Altered Strength Profile in Achilles Tendinopathy: A Systematic Review and Meta-Analysis. 38
31386582 2019
Tendinopathy: Pathophysiology, Therapeutic Options, and Role of Nutraceutics. A Narrative Literature Review. 38
31394838 2019
Systematic review of the psychometric properties of the Victorian Institute of Sports Assessment - Achilles tendinopathy questionnaire. 38
31429326 2019
High volume injection with and without corticosteroid in chronic midportion achilles tendinopathy. 38
31044450 2019
Identification of Inflammatory Mediators in Tendinopathy Using a Murine Subacromial Impingement Model. 38
31378986 2019
ICON 2019: International Scientific Tendinopathy Symposium Consensus: Clinical Terminology. 38
31399426 2019
Cheiroarthropathy and tendinopathy in diabetes. 38
30920669 2019
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling. 38
30825206 2019
Flexor Hallucis Longus Transfer Improves Achilles Tendon Load to Failure in Surgery for Non-Insertional Tendinopathy: A Biomechanical Study. 38
31436659 2019
Prevalence of Patellar Tendinopathy and Patellar Tendon Abnormality in Male Collegiate Basketball Players: A Cross-Sectional Study. 38
31424974 2019
Effects of hypertonic dextrose injection in chronic supraspinatus tendinopathy of the shoulder: a randomized placebo-controlled trial. 38
30543266 2019
Up to a quarter of patients with certain chronic recalcitrant tendinopathies may have central sensitisation: a prospective cohort of more than 300 patients. 38
31308939 2019
The Role of Extracorporeal Shockwave Therapy in Return to Competition for Endurance Runners: Two Case Reports. 38
31411811 2019
Calcific tendinopathy of the direct head of rectus femoris: a rare cause of groin pain treated with ultrasound guided percutaneous irrigation. 38
31372946 2019
Clinical Outcomes and Complications of Peroneal Tendon Sheath Ultrasound-Guided Corticosteroid Injection. 38
31068007 2019
Chronic Disorders of the Peroneal Tendons: Current Concepts Review of the Literature. 38
31394550 2019
Spontaneous Rupture of the Extensor Pollicis Longus Tendon With Repair and Contralateral Prophylactic Decompression: A Case Report and Review of the Literature. 38
30389334 2019
Beach tennis injuries: a cross-sectional survey of 206 elite and recreational players. 38
31356120 2019
Inter- and intra-rater reliability of ultrasound tissue characterization (UTC) in patellar tendons. 38
31033002 2019
Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix. 38
31148334 2019
In vivo evaluation of human patellar tendon microstructure and microcirculation with diffusion MRI. 38
31407413 2019
A comparative study of the efficacy of ultrasonics and extracorporeal shock wave in the treatment of tennis elbow: a meta-analysis of randomized controlled trials. 38
31387611 2019
Role of Ultrasound in the Detection of Rotator-Cuff Syndrome: An Observational Study. 38
31386649 2019
Management of Chronic Tendon Injuries. 38
31361101 2019
The Association Between Symptoms of Depression and Office Visits in Patients With Nontraumatic Upper-Extremity Illness. 38
31300225 2019
Calcified or ossified benign soft tissue lesions that may simulate malignancy. 38
31297550 2019
Regulatory mechanisms and clinical manifestations of musculoskeletal aging. 38
30919498 2019

Variations for Tendinopathy

Expression for Tendinopathy

Search GEO for disease gene expression data for Tendinopathy.

Pathways for Tendinopathy

Pathways related to Tendinopathy according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
Show member pathways
Show member pathways
11.88 MMP1 CASP8 CASP3
Show member pathways
4 11.69 MMP1 CASP8 CASP3
Show member pathways
6 11.41 CASP8 CASP3
7 11.36 CASP8 CASP3
8 11.31 VCAN MMP1
9 11.26 CASP8 CASP3
10 11.2 MMP1 CASP3
Show member pathways
11.17 CASP8 CASP3
12 11.09 CASP8 CASP3
13 11.02 VCAN MMP1
14 11.01 CASP8 CASP3
15 10.99 MMP1 CASP8 CASP3

GO Terms for Tendinopathy

Cellular components related to Tendinopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.77 VCAN MMP8 ENPP1 COL5A1 COL27A1
2 extracellular region GO:0005576 9.73 VCAN MMP8 MMP1 ENPP1 COL5A1 COL27A1
3 endoplasmic reticulum lumen GO:0005788 9.5 VCAN COL5A1 COL27A1
4 collagen-containing extracellular matrix GO:0062023 9.26 VCAN MMP8 COL5A1 COL27A1
5 death-inducing signaling complex GO:0031264 9.16 CASP8 CASP3
6 extracellular matrix GO:0031012 9.02 VCAN MMP8 MMP1 COL5A1 COL27A1

Biological processes related to Tendinopathy according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.67 MMP8 MMP1 CASP8 CASP3
2 cellular response to organic cyclic compound GO:0071407 9.49 CASP8 CASP3
3 apoptotic signaling pathway GO:0097190 9.46 CASP8 CASP3
4 extracellular matrix disassembly GO:0022617 9.43 MMP8 MMP1
5 collagen catabolic process GO:0030574 9.4 MMP8 MMP1
6 extracellular matrix organization GO:0030198 9.33 VCAN COL5A1 COL27A1
7 response to tumor necrosis factor GO:0034612 9.32 CASP8 CASP3
8 response to antibiotic GO:0046677 9.26 CASP8 CASP3
9 hippocampus development GO:0021766 9.18 CASP3
10 execution phase of apoptosis GO:0097194 8.96 CASP8 CASP3
11 response to cobalt ion GO:0032025 8.62 CASP8 CASP3

Molecular functions related to Tendinopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.72 MMP8 MMP1 ENPP1 CASP8 CASP3
2 peptidase activity GO:0008233 9.56 MMP8 MMP1 CASP8 CASP3
3 extracellular matrix structural constituent conferring tensile strength GO:0030020 9.37 COL5A1 COL27A1
4 death receptor binding GO:0005123 9.16 CASP8 CASP3
5 cysteine-type endopeptidase activity involved in apoptotic process GO:0097153 8.96 CASP8 CASP3
6 cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097199 8.62 CASP8 CASP3

Sources for Tendinopathy

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
32 HPO
33 ICD10
34 ICD10 via Orphanet
38 LifeMap
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
55 Novoseek
58 OMIM via Orphanet
62 PubMed
71 Tocris
73 UMLS via Orphanet
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