Aliases & Classifications for Tendinosis

MalaCards integrated aliases for Tendinosis:

Name: Tendinosis 41 38 73

External Ids:

UMLS 73 C1568363

Summaries for Tendinosis

MalaCards based summary : Tendinosis is related to tendinopathy and tendinitis. An important gene associated with Tendinosis is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways are PAK Pathway and MAPK signaling pathway. The drugs Menthol and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, whole blood and bone, and related phenotypes are homeostasis/metabolism and behavior/neurological

Wikipedia : 76 Tendinosis, means or sometimes called chronic tendinitis, chronic tendinopathy, or chronic tendon... more...

Related Diseases for Tendinosis

Diseases related to Tendinosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 tendinopathy 30.3 DCN MMP1
2 tendinitis 11.3
3 myasthenic syndrome, congenital, 21, presynaptic 10.8 CHAT SLC18A3
4 presynaptic congenital myasthenic syndromes 10.8 CHAT SLC18A3
5 superior limbic keratoconjunctivitis 10.6 MMP1 MMP3
6 hypoganglionosis 10.6 ACHE TH
7 supranuclear palsy, progressive, 1 10.6 ACHE CHAT TH
8 spastic entropion 10.5 MMP1 MMP3
9 aortic disease 10.4 TGFB2 TGFBR2 TIMP1
10 conjunctivochalasis 10.4 MMP1 MMP3 TIMP1
11 bone deterioration disease 10.4 MMP1 MMP3 TIMP1
12 varicose veins 10.3 MMP1 MMP3 TIMP1
13 aortic aneurysm, familial thoracic 1 10.3 MMP1 TGFB2 TGFBR2
14 bone inflammation disease 10.3 MMP1 MMP3 TIMP1
15 gingival fibromatosis 10.3 MMP1 MMP3 TIMP1
16 neonatal hypoxic and ischemic brain injury 10.2 BDNF TH
17 periodontitis 10.2 MMP1 MMP3 TIMP1
18 sydenham chorea 10.1 BDNF CXCL10
19 periodontal disease 10.1 MMP1 MMP3 TIMP1
20 toxic encephalopathy 10.1 ACHE BDNF TH
21 neuronitis 10.1
22 paine syndrome 10.0
23 bursitis 10.0
24 chronic pain 10.0
25 keratoconus 10.0 MMP1 MMP3 TGFB2 TIMP1
26 adult astrocytic tumour 9.9 BDNF MMP1 MMP3
27 central nervous system disease 9.9 ACHE BDNF CHAT TH
28 nervous system disease 9.9 ACHE BDNF CHAT TH
29 cannabis abuse 9.8 BDNF CNR1
30 eating disorder 9.8 BDNF CNR1 NPY
31 epicondylitis 9.8
32 periarthritis 9.8
33 astrocytoma 9.8
34 mood disorder 9.8 BDNF NPY TH
35 gingival overgrowth 9.8 DCN MMP1 MMP3 TIMP1
36 aortic aneurysm, familial abdominal, 1 9.8 DCN MMP1 MMP3 TIMP1
37 amnestic disorder 9.7 ACHE BDNF CHAT CNR1
38 drug dependence 9.6 BDNF CHRM2 CNR1
39 fibrosarcoma 9.5 MMP1 MMP3 TIMP1
40 parkinson disease, late-onset 9.4 ACHE BDNF CHAT CNR1 TH
41 anxiety 9.4 BDNF CNR1 NPY
42 ewing sarcoma 9.3 MMP1 MMP3 NPY PDGFRB TGFB2 TGFBR2
43 alcohol dependence 9.2 BDNF CHRM2 CNR1 NPY
44 psoriatic arthritis 9.1 MMP1 MMP3 TNFRSF1A
45 multiple sclerosis 8.4 BDNF CNR1 CXCL10 TIMP1 TNFRSF1A

Graphical network of the top 20 diseases related to Tendinosis:



Diseases related to Tendinosis

Symptoms & Phenotypes for Tendinosis

MGI Mouse Phenotypes related to Tendinosis:

46 (show all 19)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.46 ACHE BDNF CHAT CHRM2 CNR1 CXCL10
2 behavior/neurological MP:0005386 10.39 ACHE BDNF CHAT CHRM2 CNR1 DCN
3 growth/size/body region MP:0005378 10.37 CNR1 DCN NPY PDGFRB SLC17A6 TGFB2
4 mortality/aging MP:0010768 10.32 TH TIMP1 TNFRSF1A CXCL10 DCN PDGFRB
5 nervous system MP:0003631 10.28 CHAT CHRM2 CNR1 CXCL10 MMP3 NPY
6 cardiovascular system MP:0005385 10.22 CHAT CHRM2 CXCL10 PDGFRB TGFB2 TGFBR2
7 digestive/alimentary MP:0005381 10.2 BDNF CHAT CNR1 DCN NPY PDGFRB
8 endocrine/exocrine gland MP:0005379 10.14 TGFBR2 TH TIMP1 TNFRSF1A BDNF DCN
9 adipose tissue MP:0005375 10.13 ACHE CNR1 NPY PDGFRB SLC17A6 TGFBR2
10 muscle MP:0005369 10.11 ACHE CHAT CHRM2 DCN PDGFRB SLC18A3
11 craniofacial MP:0005382 10.1 ACHE BDNF DCN PDGFRB TGFB2 TGFBR2
12 integument MP:0010771 10.1 TH TNFRSF1A BDNF CHRM2 CNR1 DCN
13 normal MP:0002873 9.97 CNR1 DCN NPY PDGFRB SLC17A6 TGFBR2
14 neoplasm MP:0002006 9.91 DCN MMP1 TGFBR2 TH TIMP1 TNFRSF1A
15 no phenotypic analysis MP:0003012 9.91 ACHE BDNF CNR1 SLC17A6 SLC18A3 TH
16 reproductive system MP:0005389 9.91 ACHE BDNF CHAT CNR1 DCN PDGFRB
17 respiratory system MP:0005388 9.9 ACHE BDNF CHAT CHRM2 DCN SLC17A6
18 skeleton MP:0005390 9.7 PDGFRB SLC18A3 TGFB2 TGFBR2 TIMP1 TNFRSF1A
19 vision/eye MP:0005391 9.32 ACHE BDNF CHAT CHRM2 DCN PDGFRB

Drugs & Therapeutics for Tendinosis

Drugs for Tendinosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Menthol Approved Phase 4,Not Applicable 2216-51-5 16666
2
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 137-58-6 3676
3 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3
4 Anesthetics Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
5 Anesthetics, Local Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
6
Bupivacaine Approved, Investigational Phase 2, Phase 3 2180-92-9, 38396-39-3 2474
7
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3,Not Applicable 83-43-2 6741
8
Prednisolone Approved, Vet_approved Phase 2, Phase 3,Not Applicable 50-24-8 5755
9
Thrombin Approved, Investigational Phase 2, Phase 3
10
Betamethasone Approved, Vet_approved Phase 3 378-44-9 9782
11
Cortisone acetate Approved, Investigational Phase 3 1950-04-4, 50-04-4 5745
12 Antiemetics Phase 2, Phase 3,Not Applicable
13 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3,Not Applicable
14 Antineoplastic Agents, Hormonal Phase 2, Phase 3,Not Applicable
15 Autonomic Agents Phase 2, Phase 3,Not Applicable
16 Gastrointestinal Agents Phase 2, Phase 3,Not Applicable
17 glucocorticoids Phase 2, Phase 3,Phase 3,Not Applicable
18 Hormone Antagonists Phase 2, Phase 3,Phase 3,Not Applicable
19 Hormones Phase 2, Phase 3,Phase 3,Not Applicable
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3,Phase 3,Not Applicable
21 Methylprednisolone acetate Phase 2, Phase 3,Not Applicable
22 Methylprednisolone Hemisuccinate Phase 2, Phase 3,Not Applicable
23 Neuroprotective Agents Phase 2, Phase 3,Not Applicable
24 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
25 Prednisolone acetate Phase 2, Phase 3,Not Applicable
26 Prednisolone hemisuccinate Phase 2, Phase 3,Not Applicable
27 Prednisolone phosphate Phase 2, Phase 3,Not Applicable
28 Protective Agents Phase 2, Phase 3,Not Applicable
29 Anti-Arrhythmia Agents Phase 3,Phase 1,Phase 2,Not Applicable
30 Central Nervous System Depressants Phase 3,Phase 1,Phase 2,Not Applicable
31 Diuretics, Potassium Sparing Phase 3,Phase 1,Phase 2,Not Applicable
32 Sodium Channel Blockers Phase 3,Phase 1,Phase 2,Not Applicable
33 Anti-Asthmatic Agents Phase 3
34 Betamethasone benzoate Phase 3
35 Betamethasone dipropionate, betamethasone sodium phosphate drug combination Phase 3
36 Betamethasone sodium phosphate Phase 3
37 Betamethasone Valerate Phase 3 2152-44-5
38 Betamethasone-17,21-dipropionate Phase 3
39
Cortisone Phase 3 53-06-5 222786
40 Respiratory System Agents Phase 3
41 Calamus Nutraceutical Phase 2, Phase 3
42
Triamcinolone Approved, Vet_approved Phase 2 124-94-7 31307
43
Benzocaine Approved, Investigational Phase 2 1994-09-7, 94-09-7 2337
44 tannic acid Approved, Nutraceutical Phase 2
45 Immunosuppressive Agents Phase 2
46 triamcinolone acetonide Phase 2
47 Triamcinolone diacetate Phase 2
48 Triamcinolone hexacetonide Phase 2
49 Calcium, Dietary Not Applicable
50 Mitogens

Interventional clinical trials:

(show all 35)
# Name Status NCT ID Phase Drugs
1 Achilles Tendinosis Study; Comparison of Radiofrequency to Surgical MicroDebridement Completed NCT00534781 Phase 4
2 Radio-frequency (RF)-Based Plasma Micro-tenotomy for the Treatment of Shoulder Impingement Syndrome Completed NCT01554670 Phase 4
3 Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer Completed NCT00950053 Phase 4
4 Bundang Rehabilitative Impact Study of the Elbow Epicondylitis Completed NCT02492945 Phase 4 3ml-Rejuvinex;3ml-15%-dextrose solution
5 The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis Not yet recruiting NCT03363789 Phase 4
6 Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy Terminated NCT02978833 Phase 4
7 Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis Withdrawn NCT00420875 Phase 4
8 Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff Tendinosis Unknown status NCT00196573 Phase 3
9 A Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral Epicondylitis Completed NCT00947765 Phase 2, Phase 3 Local corticosteroid injection
10 Impact of Autologous Platelet Rich Plasma on Healing of Rotator Cuff Repairs Completed NCT01000935 Phase 2, Phase 3
11 A Dynamic Elastic Garment (DEG) in Patients With Rotator Cuff Tendinopathy Recruiting NCT03032432 Phase 3 Corticosteroid injection
12 Hyaluronate Injection for Lateral Epicondylitis Recruiting NCT02258295 Phase 3 Intragel;Saline
13 Local Injection Under US Control in GTPS. Terminated NCT01807962 Phase 3 rapidocain and bethametsaone;sterile saline
14 A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection Completed NCT01600326 Phase 2 Ultrasound guided platelet rich plasma injection
15 Effectiveness of Dextrose Injection for Osgood-Schlatter Disease Completed NCT01300754 Phase 1, Phase 2
16 Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC) Recruiting NCT03449082 Phase 2 Fibrin glue;Normal saline
17 PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis Recruiting NCT03072381 Phase 2 Corticosteroid Control - Group 2
18 Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy Enrolling by invitation NCT01843504 Phase 2
19 Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis Terminated NCT02330146 Phase 1, Phase 2 RCT-01;Placebo
20 Exercise and Shoe Orthoses in Treatment of Posterior Tibial Tendon Dysfunction Completed NCT00279630 Phase 1
21 Radiofrequency Microtenotomy for Treatment of Rotator Cuff Tendinopathy Completed NCT02275689 Not Applicable
22 Long Duration Therapeutic Ultrasound for Tendon Healing Completed NCT02466308 Not Applicable
23 Steroid Versus Platelet Rich Plasma Injection for Chronic Low Back Pain Completed NCT02334475 Not Applicable
24 Physiotherapy or Acupuncture for Lateral Epicondylitis Completed NCT02321696 Not Applicable
25 Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) Injections Completed NCT01200875
26 PRINT Trial (Platelet Rich Injection vs Needle Tenotomy) Recruiting NCT03504111 Not Applicable
27 Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients Recruiting NCT03000205 Not Applicable
28 Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma Recruiting NCT01406821 Not Applicable
29 Achilles Tendinopathy Shear Wave Elastography Study Recruiting NCT03456778 Not Applicable
30 Cellular & Biocellular Regenerative Therapy in Musculoskeletal Pain, Dysfunction,Degenerative or Inflammatory Disease Recruiting NCT03090672 Not Applicable Normal Saline
31 Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles Tendinopathy Recruiting NCT02732782 Not Applicable
32 Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic Tendinosis Active, not recruiting NCT01833598 Not Applicable
33 Percutaneous US Guided Elbow Tenotomy With the TenJet HydroSurgery System Active, not recruiting NCT03487250
34 Effects of Isoinertial Training on Rotator Cuff Tendinopathy Not yet recruiting NCT02982460 Not Applicable
35 Long-Term Follow-up of the Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis Withdrawn NCT02655042

Search NIH Clinical Center for Tendinosis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tendinosis cell therapies at LifeMap Discovery.

Genetic Tests for Tendinosis

Anatomical Context for Tendinosis

MalaCards organs/tissues related to Tendinosis:

41
Skin, Whole Blood, Bone, Bone Marrow

Publications for Tendinosis

Articles related to Tendinosis:

(show top 50) (show all 74)
# Title Authors Year
1
Prevalence of Asymptomatic Achilles Tendinosis. ( 29855207 )
2018
2
Evaluation of tendinosis of the long head of the biceps tendon by strain and shear wave elastography. ( 29730686 )
2018
3
Greater trochanteric pain syndrome and gluteus medius and minimus tendinosis: nonsurgical treatment. ( 29182042 )
2018
4
The Dodo Bird is not Extinct: Ultrasound Imaging for Supraspinatus Tendinosis. ( 29979204 )
2018
5
Radiofrequency Microdebridement Versus Surgical Decompression for Achilles Tendinosis: A Randomized Controlled Trial. ( 28495412 )
2017
6
Proximal Hamstring Tendinosis and Partial Ruptures. ( 28195608 )
2017
7
Platelet-Rich Plasma Injections as a Treatment for Refractory Patellar Tendinosis: A Meta-Analysis of Randomised Trials. ( 28854761 )
2017
8
Tendinosis (Tendinitis) ( 28846334 )
2017
9
Ultrasonic Percutaneous Tenotomy for Recalcitrant Calcific Triceps Tendinosis in a Competitive Strongman: A Case Report. ( 28498222 )
2017
10
Predicting Failure of Nonoperative Treatment for Insertional Achilles Tendinosis. ( 28884594 )
2017
11
Comparison of Clinical Efficacy Among Endoscopy-Assisted Radio-Frequency Ablation, Extracorporeal Shockwaves, and Eccentric Exercises in Treatment of Insertional Achilles Tendinosis. ( 27723374 )
2016
12
Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. ( 27469590 )
2016
13
Technical Innovation Case Report: Ultrasound-Guided Prolotherapy Injection for Insertional Achilles Calcific Tendinosis. ( 27974984 )
2016
14
Greater Trochanteric Pain Syndrome: Percutaneous Tendon Fenestration Versus Platelet-Rich Plasma Injection for Treatment of Gluteal Tendinosis. ( 27663654 )
2016
15
T2 * relaxation time in Achilles tendinosis and controls and its correlation with clinical score. ( 26605756 )
2016
16
Efficacy of Achilles Suture Bridge Technique for Insertional Achilles Tendinosis in an Obese and Athletic Patient. ( 27644578 )
2016
17
Plantaris Excision Reduces Pain in Midportion Achilles Tendinopathy Even in the Absence of Plantaris Tendinosis. ( 28203584 )
2016
18
Surgical Technique: Jumper's Knee-Arthroscopic Treatment of Chronic Tendinosis of the Patellar Tendon. ( 28149740 )
2016
19
CORR Insights(Ar): Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. ( 27572298 )
2016
20
High Power Laser for Treatment of Achilles Tendinosis - a Single Blind Randomized Placebo Controlled Clinical Study. ( 27330704 )
2016
21
Return to Sport and Physical Activity After Calcaneoplasty for Insertional Achilles Tendinosis. ( 27600485 )
2016
22
Results of Surgical Treatment of Chronic Patellar Tendinosis (Jumper's Knee): A Systematic Review of the Literature. ( 26248496 )
2015
23
The neuromechanical adaptations to Achilles tendinosis. ( 26046962 )
2015
24
Gastrocnemius tendinosis-A frequent finding on MRI knee examination. ( 26456309 )
2015
25
Achilles tendinosis: treatment options. ( 25729512 )
2015
26
Quantitative MRI characterization of arthroscopically verified supraspinatus pathology: comparison of tendon tears, tendinosis and asymptomatic supraspinatus tendons with T2 mapping. ( 25739912 )
2015
27
Management of rotator cuff calcific tendinosis guided by ultrasound elastography. ( 26143386 )
2015
28
Retraction. Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. ( 25878311 )
2015
29
A retrospective comparison of the management of recalcitrant lateral elbow tendinosis: platelet-rich plasma injections versus surgery. ( 26034445 )
2015
30
Asymptomatic Elite Adolescent Tennis Players' Signs of Tendinosis in Their Dominant Shoulder Compared With Their Nondominant Shoulder. ( 26651279 )
2015
31
Peroneal tendinosis as a predisposing factor for the acute lateral ankle sprain in runners. ( 25786820 )
2015
32
Amniotic Tissues for the Treatment of Chronic Plantar Fasciosis and Achilles Tendinosis. ( 26491722 )
2015
33
The molecular systemic and local effects of intra-tendinous injection of Platelet Rich Plasma in tendinosis: preliminary results on a rat model with ELISA method. ( 26261788 )
2015
34
Update to the retraction of "Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results" by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. ( 26085535 )
2015
35
The impact of posture on wrist tendinosis among blue-collar workers: the San Francisco study. ( 24669549 )
2014
36
Percutaneous ultrasonic tenotomy for chronic elbow tendinosis: a prospective study. ( 25306494 )
2014
37
Combined intra-tendinous injection of Platelet Rich Plasma and bevacizumab accelerates and improves healing compared to Platelet Rich Plasma in tendinosis: comprehensive assessment on a rat model. ( 25489554 )
2014
38
An Achilles tendinosis masking an intramedullary astrocytoma. ( 25322734 )
2014
39
Trigger finger, tendinosis, and intratendinous gene expression. ( 22882155 )
2014
40
Sonoelastography findings of biceps tendinitis and tendinosis. ( 25368684 )
2014
41
Plantar Flexor Muscle Architecture Changes as a Result of Eccentric Exercise in Patients With Achilles Tendinosis. ( 25037955 )
2014
42
Injectable treatments for noninsertional achilles tendinosis: a systematic review. ( 23637232 )
2013
43
Efficacy of intra-tendinous injection of platelet-rich plasma in treating tendinosis: comprehensive assessment of a rat model. ( 23801419 )
2013
44
The plantaris tendon in association with mid-portion Achilles tendinosis: tendinosis-like morphological features and presence of a non-neuronal cholinergic system. ( 23378267 )
2013
45
Early weightbearing using Achilles suture bridge technique for insertional Achilles tendinosis: a review of 43 patients. ( 23669005 )
2013
46
Dynamic contrast enhanced magnetic resonance imaging in chronic Achilles tendinosis. ( 24261480 )
2013
47
Flexor hallucis longus tendon transfer in treatment of Achilles tendinosis. ( 23283373 )
2013
48
Acute calcific tendinosis of the flexor hallucis brevis: case report. ( 23729205 )
2013
49
Effects of tendon viscoelasticity in Achilles tendinosis on explosive performance and clinical severity in athletes. ( 22830527 )
2012
50
Platelet rich plasma treatment for chronic Achilles tendinosis. ( 22735279 )
2012

Variations for Tendinosis

Expression for Tendinosis

Search GEO for disease gene expression data for Tendinosis.

Pathways for Tendinosis

Pathways related to Tendinosis according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.09 BDNF CXCL10 PDGFRB TGFB2 TGFBR2 TIMP1
2 12.61 BDNF PDGFRB TGFB2 TGFBR2 TNFRSF1A
3
Show member pathways
12.59 DCN MMP1 MMP3 TGFB2 TIMP1
4 12.45 CNR1 NPY SLC17A6 TH
5
Show member pathways
12.43 ACHE CHAT CHRM2 MMP1 SLC17A6 SLC18A3
6 12.27 PDGFRB TGFB2 TGFBR2 TNFRSF1A
7 11.91 TGFB2 TGFBR2 TNFRSF1A
8 11.89 MMP1 TGFB2 TGFBR2 TNFRSF1A
9 11.84 MMP1 MMP3 TIMP1
10 11.83 BDNF CHAT CHRM2 TH
11 11.81 CXCL10 MMP3 TNFRSF1A
12
Show member pathways
11.81 BDNF TGFB2 TGFBR2 TIMP1 TNFRSF1A
13
Show member pathways
11.76 MMP1 MMP3 TIMP1
14 11.71 MMP1 MMP3 TGFB2
15 11.68 DCN TGFB2 TGFBR2
16 11.63 BDNF CHAT TH
17
Show member pathways
11.5 MMP1 MMP3 TNFRSF1A
18 11.46 MMP1 MMP3 TIMP1
19 11.41 MMP3 PDGFRB TGFB2 TIMP1
20 11.37 ACHE TGFB2 TH
21 11.3 CXCL10 TIMP1 TNFRSF1A
22 10.89 MMP1 TIMP1
23
Show member pathways
10.78 ACHE CHAT TH
24 10.36 ACHE CHAT
25 10 ACHE CHAT SLC18A3 TH

GO Terms for Tendinosis

Cellular components related to Tendinosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.85 ACHE BDNF CXCL10 DCN MMP1 MMP3
2 synapse GO:0045202 9.65 ACHE CHAT CHRM2 SLC17A6 SLC18A3
3 axon GO:0030424 9.62 BDNF CNR1 TGFB2 TH
4 extracellular space GO:0005615 9.61 ACHE BDNF CXCL10 DCN MMP3 NPY
5 extracellular matrix GO:0031012 9.02 DCN MMP1 MMP3 TGFB2 TIMP1

Biological processes related to Tendinosis according to GeneCards Suite gene sharing:

(show all 24)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.97 CXCL10 PDGFRB TGFB2 TGFBR2 TIMP1
2 cell-cell signaling GO:0007267 9.91 BDNF CXCL10 NPY TGFB2
3 regulation of cell proliferation GO:0042127 9.85 CXCL10 TGFB2 TGFBR2 TNFRSF1A
4 regulation of signaling receptor activity GO:0010469 9.85 BDNF CXCL10 NPY TGFB2 TIMP1
5 response to organic cyclic compound GO:0014070 9.79 PDGFRB TGFBR2 TH
6 animal organ morphogenesis GO:0009887 9.79 DCN TGFBR2 TH
7 negative regulation of angiogenesis GO:0016525 9.77 CXCL10 DCN TGFB2
8 response to lipopolysaccharide GO:0032496 9.72 CNR1 CXCL10 DCN TH TNFRSF1A
9 memory GO:0007613 9.69 BDNF CNR1 TH
10 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.67 DCN PDGFRB TGFB2
11 extracellular matrix disassembly GO:0022617 9.67 DCN MMP1 MMP3 TIMP1
12 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.65 CHRM2 CNR1 NPY
13 positive regulation of protein oligomerization GO:0032461 9.59 MMP1 MMP3
14 pathway-restricted SMAD protein phosphorylation GO:0060389 9.58 TGFB2 TGFBR2
15 secondary palate development GO:0062009 9.58 TGFB2 TGFBR2
16 atrioventricular valve morphogenesis GO:0003181 9.56 TGFB2 TGFBR2
17 aging GO:0007568 9.55 CNR1 DCN PDGFRB TGFBR2 TIMP1
18 membranous septum morphogenesis GO:0003149 9.54 TGFB2 TGFBR2
19 dopamine biosynthetic process GO:0042416 9.52 TGFB2 TH
20 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007 9.43 TGFB2 TGFBR2
21 neurotransmitter biosynthetic process GO:0042136 9.43 ACHE CHAT TH
22 cytokine-mediated signaling pathway GO:0019221 9.43 CXCL10 DCN MMP1 MMP3 TIMP1 TNFRSF1A
23 endocardial cushion fusion GO:0003274 9.4 TGFB2 TGFBR2
24 wound healing GO:0042060 9.02 DCN PDGFRB TGFB2 TGFBR2 TIMP1

Molecular functions related to Tendinosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acetylcholine binding GO:0042166 8.62 ACHE SLC18A3

Sources for Tendinosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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