Aliases & Classifications for Tendinosis

MalaCards integrated aliases for Tendinosis:

Name: Tendinosis 42 39 74

External Ids:

UMLS 74 C1568363

Summaries for Tendinosis

MalaCards based summary : Tendinosis is related to tendinopathy and tendinitis. An important gene associated with Tendinosis is CHAT (Choline O-Acetyltransferase), and among its related pathways/superpathways are PAK Pathway and MAPK signaling pathway. The drugs Lidocaine and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and whole blood, and related phenotypes are homeostasis/metabolism and behavior/neurological

Wikipedia : 77 Tendinopathy, also known as tendinitis or tendinosis, is a type of tendon disorder that results in pain,... more...

Related Diseases for Tendinosis

Diseases related to Tendinosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 tendinopathy 32.5 MMP1 MMP3
2 tendinitis 11.5
3 epicondylitis 10.4
4 sydenham chorea 10.4 BDNF CXCL10
5 myasthenic syndrome, congenital, 21, presynaptic 10.4 CHAT SLC18A3
6 presynaptic congenital myasthenic syndromes 10.4 CHAT SLC18A3
7 neonatal hypoxic and ischemic brain injury 10.3 BDNF TH
8 hypoganglionosis 10.3 ACHE TH
9 superior limbic keratoconjunctivitis 10.3 MMP1 MMP3
10 supranuclear palsy, progressive, 1 10.3 ACHE CHAT TH
11 toxic encephalopathy 10.2 ACHE BDNF TH
12 spastic entropion 10.2 MMP1 MMP3
13 cannabis abuse 10.2 BDNF CNR1
14 bursitis 10.2
15 drug dependence 10.2 BDNF CHRM2 CNR1
16 adult astrocytic tumour 10.2 BDNF MMP1 MMP3
17 nervous system disease 10.1 ACHE BDNF CHAT TH
18 central nervous system disease 10.1 BDNF CHAT CNR1 TH
19 amnestic disorder 10.1 ACHE BDNF CHAT CNR1
20 eating disorder 10.1 BDNF CNR1 NPY
21 mood disorder 10.1 BDNF NPY TH
22 osteoarthritis 10.0
23 periarthritis 10.0
24 astrocytoma 10.0
25 parkinson disease, late-onset 10.0 ACHE BDNF CHAT CNR1 TH
26 alcohol dependence 10.0 BDNF CHRM2 CNR1 NPY
27 anxiety 10.0 BDNF CNR1 NPY
28 conjunctivochalasis 9.9 MMP1 MMP3 TIMP1
29 aortic aneurysm, familial abdominal, 1 9.9 MMP1 MMP3 TIMP1
30 gingival fibromatosis 9.9 MMP1 MMP3 TIMP1
31 carotid artery disease 9.9 MMP1 MMP3 TIMP1
32 varicose veins 9.9 MMP1 MMP3 TIMP1
33 bone inflammation disease 9.9 MMP1 MMP3 TIMP1
34 multiple sclerosis 9.9 BDNF CNR1 CXCL10 TNFRSF1A
35 periodontitis 9.9 MMP1 MMP3 TIMP1
36 periodontal disease 9.8 MMP1 MMP3 TIMP1
37 gingival overgrowth 9.8 DCN MMP1 MMP3 TIMP1
38 psoriatic arthritis 9.7 MMP1 MMP3 TNFRSF1A
39 loeys-dietz syndrome 4 9.7 TGFB2 TGFBR2
40 fibrosarcoma 9.5 MMP1 MMP3 TIMP1
41 ewing sarcoma 9.1 MMP1 MMP3 NPY PDGFRB TGFB2 TGFBR2

Graphical network of the top 20 diseases related to Tendinosis:



Diseases related to Tendinosis

Symptoms & Phenotypes for Tendinosis

MGI Mouse Phenotypes related to Tendinosis:

47 (show all 19)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.46 ACHE BDNF CHAT CHRM2 CNR1 CXCL10
2 behavior/neurological MP:0005386 10.39 ACHE BDNF CHAT CHRM2 CNR1 DCN
3 growth/size/body region MP:0005378 10.37 ACHE BDNF CHAT CHRM2 CNR1 DCN
4 mortality/aging MP:0010768 10.32 ACHE BDNF CHAT CNR1 CXCL10 DCN
5 nervous system MP:0003631 10.28 ACHE BDNF CHAT CHRM2 CNR1 CXCL10
6 cardiovascular system MP:0005385 10.22 CHAT CHRM2 CXCL10 PDGFRB TGFB2 TGFBR2
7 digestive/alimentary MP:0005381 10.2 BDNF CHAT CNR1 DCN NPY PDGFRB
8 endocrine/exocrine gland MP:0005379 10.14 BDNF DCN PDGFRB TGFB2 TGFBR2 TH
9 adipose tissue MP:0005375 10.13 ACHE CNR1 NPY PDGFRB SLC17A6 TGFBR2
10 muscle MP:0005369 10.11 ACHE CHAT CHRM2 DCN PDGFRB SLC18A3
11 craniofacial MP:0005382 10.1 ACHE BDNF DCN PDGFRB TGFB2 TGFBR2
12 integument MP:0010771 10.1 BDNF CHRM2 CNR1 DCN PDGFRB SLC17A6
13 normal MP:0002873 9.97 BDNF CHAT CNR1 DCN NPY PDGFRB
14 neoplasm MP:0002006 9.91 DCN MMP1 TGFBR2 TH TIMP1 TNFRSF1A
15 no phenotypic analysis MP:0003012 9.91 ACHE BDNF CNR1 SLC17A6 SLC18A3 TH
16 reproductive system MP:0005389 9.91 ACHE BDNF CHAT CNR1 DCN PDGFRB
17 respiratory system MP:0005388 9.9 ACHE BDNF CHAT CHRM2 DCN SLC17A6
18 skeleton MP:0005390 9.7 CHAT CNR1 DCN MMP3 NPY PDGFRB
19 vision/eye MP:0005391 9.32 ACHE BDNF CHAT CHRM2 DCN PDGFRB

Drugs & Therapeutics for Tendinosis

Drugs for Tendinosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 64)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 137-58-6 3676
2 Anesthetics Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
3 Anesthetics, Local Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
4 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3
5
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3,Not Applicable 83-43-2 6741
6
Methylprednisolone hemisuccinate Approved Phase 2, Phase 3,Not Applicable 2921-57-5
7
Prednisolone phosphate Approved, Vet_approved Phase 2, Phase 3,Not Applicable 302-25-0
8
Prednisolone Approved, Vet_approved Phase 2, Phase 3,Not Applicable 50-24-8 5755
9
Bupivacaine Approved, Investigational Phase 2, Phase 3,Not Applicable 2180-92-9, 38396-39-3 2474
10
Thrombin Approved, Investigational Phase 2, Phase 3
11
Betamethasone Approved, Vet_approved Phase 3 378-44-9 9782
12
Prednisolone hemisuccinate Experimental Phase 2, Phase 3,Not Applicable 2920-86-7
13
Cortisone Experimental Phase 3 53-06-5 222786
14 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
15 Central Nervous System Depressants Phase 3,Phase 1,Phase 2,Not Applicable
16 Sodium Channel Blockers Phase 3,Phase 1,Phase 2,Not Applicable
17 Anti-Arrhythmia Agents Phase 3,Phase 1,Phase 2,Not Applicable
18 Diuretics, Potassium Sparing Phase 3,Phase 1,Phase 2,Not Applicable
19 Hormones Phase 2, Phase 3,Phase 3,Not Applicable
20 Autonomic Agents Phase 2, Phase 3,Not Applicable
21 Prednisolone acetate Phase 2, Phase 3,Not Applicable
22 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3,Not Applicable
23 Protective Agents Phase 2, Phase 3,Not Applicable
24 glucocorticoids Phase 2, Phase 3,Phase 3,Not Applicable
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3,Phase 3,Not Applicable
26 Gastrointestinal Agents Phase 2, Phase 3,Not Applicable
27 Neuroprotective Agents Phase 2, Phase 3,Not Applicable
28 Antineoplastic Agents, Hormonal Phase 2, Phase 3,Not Applicable
29 Hormone Antagonists Phase 2, Phase 3,Phase 3,Not Applicable
30 Antiemetics Phase 2, Phase 3,Not Applicable
31 Methylprednisolone Acetate Phase 2, Phase 3,Not Applicable
32 Calamus Phase 2, Phase 3
33 Betamethasone-17,21-dipropionate Phase 3
34 Anti-Asthmatic Agents Phase 3
35 Betamethasone benzoate Phase 3
36 Betamethasone sodium phosphate Phase 3
37 Betamethasone Valerate Phase 3 2152-44-5
38 Betamethasone dipropionate, betamethasone sodium phosphate drug combination Phase 3
39 Respiratory System Agents Phase 3
40
Allopurinol Approved Phase 2 315-30-0 2094
41
Triamcinolone Approved, Vet_approved Phase 2 124-94-7 31307
42
Benzocaine Approved, Investigational Phase 2 94-09-7, 1994-09-7 2337
43
tannic acid Approved Phase 2 1401-55-4
44 Antirheumatic Agents Phase 2
45 Fibrin Tissue Adhesive Phase 2
46 Hemostatics Phase 2
47 Antimetabolites Phase 2
48 Free Radical Scavengers Phase 2
49 Coagulants Phase 2
50 Antioxidants Phase 2

Interventional clinical trials:

(show all 37)
# Name Status NCT ID Phase Drugs
1 Achilles Tendinosis Study; Comparison of Radiofrequency to Surgical MicroDebridement Completed NCT00534781 Phase 4
2 Radio-frequency (RF)-Based Plasma Micro-tenotomy for the Treatment of Shoulder Impingement Syndrome Completed NCT01554670 Phase 4
3 Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon Transfer Completed NCT00950053 Phase 4
4 Bundang Rehabilitative Impact Study of the Elbow Epicondylitis Completed NCT02492945 Phase 4 3ml-Rejuvinex;3ml-15%-dextrose solution
5 A Dynamic Elastic Garment (DEG) in Patients With Rotator Cuff Tendinopathy Recruiting NCT03032432 Phase 4 Corticosteroid injection
6 The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis Not yet recruiting NCT03363789 Phase 4
7 Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy Terminated NCT02978833 Phase 4
8 Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis Withdrawn NCT00420875 Phase 4
9 Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff Tendinosis Unknown status NCT00196573 Phase 3
10 A Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral Epicondylitis Completed NCT00947765 Phase 2, Phase 3 Local corticosteroid injection
11 Impact of Autologous Platelet Rich Plasma on Healing of Rotator Cuff Repairs Completed NCT01000935 Phase 2, Phase 3
12 Hyaluronate Injection for Lateral Epicondylitis Recruiting NCT02258295 Phase 3 Intragel;Saline
13 Local Injection Under US Control in GTPS. Terminated NCT01807962 Phase 3 rapidocain and bethametsaone;sterile saline
14 A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection Completed NCT01600326 Phase 2 Ultrasound guided platelet rich plasma injection
15 Effectiveness of Dextrose Injection for Osgood-Schlatter Disease Completed NCT01300754 Phase 1, Phase 2
16 Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC) Recruiting NCT03449082 Phase 2 Fibrin glue;Normal saline
17 PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis Recruiting NCT03072381 Phase 2 Corticosteroid Control - Group 2
18 Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy Enrolling by invitation NCT01843504 Phase 2
19 Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis Terminated NCT02330146 Phase 1, Phase 2 RCT-01;Placebo
20 Exercise and Shoe Orthoses in Treatment of Posterior Tibial Tendon Dysfunction Completed NCT00279630 Phase 1
21 Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients Unknown status NCT03000205 Not Applicable
22 Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma Completed NCT01406821 Not Applicable
23 Radiofrequency Microtenotomy for Treatment of Rotator Cuff Tendinopathy Completed NCT02275689 Not Applicable
24 Long Duration Therapeutic Ultrasound for Tendon Healing Completed NCT02466308 Not Applicable
25 Steroid Versus Platelet Rich Plasma Injection for Chronic Low Back Pain Completed NCT02334475 Not Applicable
26 Physiotherapy or Acupuncture for Lateral Epicondylitis Completed NCT02321696 Not Applicable
27 Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) Injections Completed NCT01200875
28 Achilles Tendinopathy Shear Wave Elastography Study Recruiting NCT03456778 Not Applicable
29 Continued Activity During Rehabilitation in Patients With Patellar Tendinopathy Recruiting NCT03694730 Not Applicable
30 Cellular & Biocellular Regenerative Therapy in Musculoskeletal Pain, Dysfunction,Degenerative or Inflammatory Disease Recruiting NCT03090672 Not Applicable Normal Saline
31 Night Pain in Patients With Rotator Cuff Syndrome Recruiting NCT03894761 Not Applicable
32 PRINT Trial (Platelet Rich Injection vs Needle Tenotomy) Active, not recruiting NCT03504111 Not Applicable
33 Percutaneous Needle Tenotomy (PNT) Versus Platelet Rich Plasma (PRP) With PNT in the Treatment of Chronic Tendinosis Active, not recruiting NCT01833598 Not Applicable
34 Percutaneous US Guided Elbow Tenotomy With the TenJet HydroSurgery System Active, not recruiting NCT03487250
35 Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles Tendinopathy Active, not recruiting NCT02732782 Not Applicable
36 Effects of Isoinertial Training on Rotator Cuff Tendinopathy Not yet recruiting NCT02982460 Not Applicable
37 Long-Term Follow-up of the Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis Withdrawn NCT02655042

Search NIH Clinical Center for Tendinosis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Tendinosis cell therapies at LifeMap Discovery.

Genetic Tests for Tendinosis

Anatomical Context for Tendinosis

MalaCards organs/tissues related to Tendinosis:

42
Bone, Skin, Whole Blood, Testes, Bone Marrow

Publications for Tendinosis

Articles related to Tendinosis:

(show top 50) (show all 237)
# Title Authors Year
1
Prevalence of Asymptomatic Achilles Tendinosis. ( 29855207 )
2018
2
Evaluation of tendinosis of the long head of the biceps tendon by strain and shear wave elastography. ( 29730686 )
2018
3
Greater trochanteric pain syndrome and gluteus medius and minimus tendinosis: nonsurgical treatment. ( 29182042 )
2018
4
The Dodo Bird is not Extinct: Ultrasound Imaging for Supraspinatus Tendinosis. ( 29979204 )
2018
5
THE DEGREE OF TENDINOSIS IS RELATED TO SYMPTOM SEVERITY AND PHYSICAL ACTIVITY LEVELS IN PATIENTS WITH MIDPORTION ACHILLES TENDINOPATHY. ( 30090678 )
2018
6
Lateral elbow tendinosis: a review of diagnosis and management in general practice. ( 30361321 )
2018
7
Tendinosis-like changes in denervated rat Achilles tendon. ( 30497469 )
2018
8
Comparative Effectiveness of Ultrasound-Guided Intratendinous Prolotherapy Injection with Conventional Treatment to Treat Focal Supraspinatus Tendinosis. ( 30057849 )
2018
9
Achilles tendinosis does not always precede Achilles tendon rupture. ( 30267184 )
2018
10
Radiofrequency Microdebridement Versus Surgical Decompression for Achilles Tendinosis: A Randomized Controlled Trial. ( 28495412 )
2017
11
Proximal Hamstring Tendinosis and Partial Ruptures. ( 28195608 )
2017
12
Platelet-Rich Plasma Injections as a Treatment for Refractory Patellar Tendinosis: A Meta-Analysis of Randomised Trials. ( 28854761 )
2017
13
Tendinosis (Tendinitis) ( 28846334 )
2017
14
Ultrasonic Percutaneous Tenotomy for Recalcitrant Calcific Triceps Tendinosis in a Competitive Strongman: A Case Report. ( 28498222 )
2017
15
Predicting Failure of Nonoperative Treatment for Insertional Achilles Tendinosis. ( 28884594 )
2017
16
Comparison of Clinical Efficacy Among Endoscopy-Assisted Radio-Frequency Ablation, Extracorporeal Shockwaves, and Eccentric Exercises in Treatment of Insertional Achilles Tendinosis. ( 27723374 )
2016
17
Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. ( 27469590 )
2016
18
Technical Innovation Case Report: Ultrasound-Guided Prolotherapy Injection for Insertional Achilles Calcific Tendinosis. ( 27974984 )
2016
19
Greater Trochanteric Pain Syndrome: Percutaneous Tendon Fenestration Versus Platelet-Rich Plasma Injection for Treatment of Gluteal Tendinosis. ( 27663654 )
2016
20
T2 * relaxation time in Achilles tendinosis and controls and its correlation with clinical score. ( 26605756 )
2016
21
Efficacy of Achilles Suture Bridge Technique for Insertional Achilles Tendinosis in an Obese and Athletic Patient. ( 27644578 )
2016
22
Plantaris Excision Reduces Pain in Midportion Achilles Tendinopathy Even in the Absence of Plantaris Tendinosis. ( 28203584 )
2016
23
Surgical Technique: Jumper's Knee-Arthroscopic Treatment of Chronic Tendinosis of the Patellar Tendon. ( 28149740 )
2016
24
CORR Insights(Ar): Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis. ( 27572298 )
2016
25
High Power Laser for Treatment of Achilles Tendinosis - a Single Blind Randomized Placebo Controlled Clinical Study. ( 27330704 )
2016
26
Return to Sport and Physical Activity After Calcaneoplasty for Insertional Achilles Tendinosis. ( 27600485 )
2016
27
Results of Surgical Treatment of Chronic Patellar Tendinosis (Jumper's Knee): A Systematic Review of the Literature. ( 26248496 )
2015
28
The neuromechanical adaptations to Achilles tendinosis. ( 26046962 )
2015
29
Gastrocnemius tendinosis-A frequent finding on MRI knee examination. ( 26456309 )
2015
30
Achilles tendinosis: treatment options. ( 25729512 )
2015
31
Quantitative MRI characterization of arthroscopically verified supraspinatus pathology: comparison of tendon tears, tendinosis and asymptomatic supraspinatus tendons with T2 mapping. ( 25739912 )
2015
32
Management of rotator cuff calcific tendinosis guided by ultrasound elastography. ( 26143386 )
2015
33
Retraction. Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. ( 25878311 )
2015
34
A retrospective comparison of the management of recalcitrant lateral elbow tendinosis: platelet-rich plasma injections versus surgery. ( 26034445 )
2015
35
Asymptomatic Elite Adolescent Tennis Players' Signs of Tendinosis in Their Dominant Shoulder Compared With Their Nondominant Shoulder. ( 26651279 )
2015
36
Peroneal tendinosis as a predisposing factor for the acute lateral ankle sprain in runners. ( 25786820 )
2015
37
Amniotic Tissues for the Treatment of Chronic Plantar Fasciosis and Achilles Tendinosis. ( 26491722 )
2015
38
The molecular systemic and local effects of intra-tendinous injection of Platelet Rich Plasma in tendinosis: preliminary results on a rat model with ELISA method. ( 26261788 )
2015
39
Update to the retraction of "Skin-derived fibroblasts for the treatment of refractory Achilles tendinosis: preliminary short-term results" by H. Obaid, A. Clarke, P. Rosenfeld, C. Leach, and D. Connell. J Bone Joint Surg Am. 2012 Feb 1;94(3):193-200. ( 26085535 )
2015
40
The impact of posture on wrist tendinosis among blue-collar workers: the San Francisco study. ( 24669549 )
2014
41
Percutaneous ultrasonic tenotomy for chronic elbow tendinosis: a prospective study. ( 25306494 )
2014
42
Combined intra-tendinous injection of Platelet Rich Plasma and bevacizumab accelerates and improves healing compared to Platelet Rich Plasma in tendinosis: comprehensive assessment on a rat model. ( 25489554 )
2014
43
An Achilles tendinosis masking an intramedullary astrocytoma. ( 25322734 )
2014
44
Trigger finger, tendinosis, and intratendinous gene expression. ( 22882155 )
2014
45
Sonoelastography findings of biceps tendinitis and tendinosis. ( 25368684 )
2014
46
Plantar Flexor Muscle Architecture Changes as a Result of Eccentric Exercise in Patients With Achilles Tendinosis. ( 25037955 )
2014
47
Injectable treatments for noninsertional achilles tendinosis: a systematic review. ( 23637232 )
2013
48
Efficacy of intra-tendinous injection of platelet-rich plasma in treating tendinosis: comprehensive assessment of a rat model. ( 23801419 )
2013
49
The plantaris tendon in association with mid-portion Achilles tendinosis: tendinosis-like morphological features and presence of a non-neuronal cholinergic system. ( 23378267 )
2013
50
Early weightbearing using Achilles suture bridge technique for insertional Achilles tendinosis: a review of 43 patients. ( 23669005 )
2013

Variations for Tendinosis

Expression for Tendinosis

Search GEO for disease gene expression data for Tendinosis.

Pathways for Tendinosis

Pathways related to Tendinosis according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.1 BDNF CXCL10 PDGFRB TGFB2 TGFBR2 TIMP1
2 12.63 BDNF PDGFRB TGFB2 TGFBR2 TNFRSF1A
3
Show member pathways
12.61 DCN MMP1 MMP3 TGFB2 TIMP1
4 12.47 CNR1 NPY SLC17A6 TH
5
Show member pathways
12.43 ACHE CHAT CHRM2 MMP1 SLC17A6 SLC18A3
6 12.23 PDGFRB TGFB2 TGFBR2 TNFRSF1A
7
Show member pathways
12.15 BDNF PDGFRB TGFB2 TIMP1
8 11.98 MMP1 TGFB2 TGFBR2 TNFRSF1A
9 11.95 BDNF CHAT CHRM2 TH
10 11.93 TGFB2 TGFBR2 TNFRSF1A
11 11.86 MMP1 MMP3 TIMP1
12 11.84 CXCL10 MMP3 TNFRSF1A
13
Show member pathways
11.81 BDNF TGFB2 TGFBR2 TIMP1 TNFRSF1A
14
Show member pathways
11.78 MMP1 MMP3 TIMP1
15 11.74 MMP1 MMP3 TGFB2
16 11.72 DCN TGFB2 TGFBR2
17 11.65 BDNF CHAT TH
18 11.61 BDNF PDGFRB TGFB2 TIMP1
19
Show member pathways
11.52 MMP1 MMP3 TNFRSF1A
20 11.51 MMP3 PDGFRB TGFB2 TIMP1
21 11.49 MMP1 MMP3 TIMP1
22 11.43 ACHE TGFB2 TH
23 11.34 CXCL10 TIMP1 TNFRSF1A
24 11.31 BDNF CXCL10 MMP3 TGFB2
25 11.2 BDNF TGFB2 TGFBR2
26 10.92 MMP1 TIMP1
27 10.9 BDNF CXCL10 PDGFRB TGFB2 TIMP1
28
Show member pathways
10.84 ACHE CHAT TH
29 10.38 ACHE CHAT
30 10 ACHE CHAT SLC18A3 TH

GO Terms for Tendinosis

Cellular components related to Tendinosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 ACHE BDNF CXCL10 DCN MMP3 NPY
2 extracellular matrix GO:0031012 9.46 DCN MMP1 MMP3 TIMP1
3 extracellular region GO:0005576 9.32 ACHE BDNF CXCL10 DCN MMP1 MMP3

Biological processes related to Tendinosis according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.96 CXCL10 PDGFRB TGFB2 TGFBR2 TIMP1
2 regulation of signaling receptor activity GO:0010469 9.88 BDNF CXCL10 NPY TGFB2 TIMP1
3 response to organic cyclic compound GO:0014070 9.79 PDGFRB TGFBR2 TH
4 animal organ morphogenesis GO:0009887 9.78 DCN TGFBR2 TH
5 negative regulation of angiogenesis GO:0016525 9.77 CXCL10 DCN TGFB2
6 memory GO:0007613 9.72 BDNF CNR1 TH
7 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.69 DCN PDGFRB TGFB2
8 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.67 CHRM2 CNR1 NPY
9 response to lipopolysaccharide GO:0032496 9.67 CNR1 CXCL10 DCN TH
10 cytokine-mediated signaling pathway GO:0019221 9.65 CXCL10 MMP1 MMP3 TIMP1 TNFRSF1A
11 extracellular matrix disassembly GO:0022617 9.63 MMP1 MMP3 TIMP1
12 response to hypoxia GO:0001666 9.61 TGFB2 TGFBR2 TH
13 positive regulation of protein oligomerization GO:0032461 9.59 MMP1 MMP3
14 secondary palate development GO:0062009 9.58 TGFB2 TGFBR2
15 pathway-restricted SMAD protein phosphorylation GO:0060389 9.58 TGFB2 TGFBR2
16 atrioventricular valve morphogenesis GO:0003181 9.57 TGFB2 TGFBR2
17 dopamine biosynthetic process GO:0042416 9.54 TGFB2 TH
18 membranous septum morphogenesis GO:0003149 9.52 TGFB2 TGFBR2
19 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation GO:1905007 9.4 TGFB2 TGFBR2
20 aging GO:0007568 9.35 CNR1 DCN PDGFRB TGFBR2 TIMP1
21 neurotransmitter biosynthetic process GO:0042136 9.33 ACHE CHAT TH
22 endocardial cushion fusion GO:0003274 9.32 TGFB2 TGFBR2
23 wound healing GO:0042060 9.02 DCN PDGFRB TGFB2 TGFBR2 TIMP1

Sources for Tendinosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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