MCID: TNS001
MIFTS: 40

Tenosynovial Giant Cell Tumor

Categories: Bone diseases, Cancer diseases, Muscle diseases

Aliases & Classifications for Tenosynovial Giant Cell Tumor

MalaCards integrated aliases for Tenosynovial Giant Cell Tumor:

Name: Tenosynovial Giant Cell Tumor 12 15 17
Fibrous Histiocytoma of Tendon Sheath 12 71
Giant Cell Tumour of Tendon Sheath 12
Giant Cell Tumor of Tendon Sheath 12
Giant Cell Tumour of Tenosynovium 12
Giant Cell Tumor of Tenosynovium 12
Tenosynovial Giant Cell Tumour 12

Classifications:



External Ids:

Disease Ontology 12 DOID:314
ICD9CM 34 727.02
MeSH 43 D000070779
NCIt 49 C3402
SNOMED-CT 67 310605004
UMLS 71 C1318543

Summaries for Tenosynovial Giant Cell Tumor

MalaCards based summary : Tenosynovial Giant Cell Tumor, also known as fibrous histiocytoma of tendon sheath, is related to pigmented villonodular synovitis and malignant giant cell tumor of the tendon sheath. An important gene associated with Tenosynovial Giant Cell Tumor is CSF1 (Colony Stimulating Factor 1), and among its related pathways/superpathways are Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions and Hematopoietic cell lineage. The drugs Sargramostim and Grapefruit Seed Extract have been mentioned in the context of this disorder. Affiliated tissues include bone, breast and brain, and related phenotypes are cellular and homeostasis/metabolism

Wikipedia : 74 Pigmented villonodular synovitis (PVNS) , also known as intra-articular giant-cell tumor of the tendon... more...

Related Diseases for Tenosynovial Giant Cell Tumor

Diseases related to Tenosynovial Giant Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 237, show less)
# Related Disease Score Top Affiliating Genes
1 pigmented villonodular synovitis 33.5 SERPINA3 CSF1R CSF1 CD68
2 malignant giant cell tumor of the tendon sheath 32.7 CSF1R CSF1 COL6A3 CD68
3 villonodular synovitis 32.0 CSF1 CD68
4 benign giant cell tumor 31.2 USP6 SERPINA3 CSF1R CSF1 CD68
5 nodular tenosynovitis 30.9 SERPINA3 AKTIP
6 giant cell reparative granuloma 30.6 USP6 SERPINA3 CD68
7 multicentric reticulohistiocytosis 30.6 SERPINA3 CSF1 CD68
8 pleomorphic lipoma 30.5 SERPINA3 CD68 CD34
9 lipomatosis, multiple 30.3 SERPINA3 KIT CD34
10 bone giant cell tumor 30.2 USP6 SERPINA3 CSF1 CD68
11 desmoid tumor 30.1 KIT CDKN2A CD34
12 fibroma 30.1 USP6 SERPINA3 CD68 CD34
13 muscle cancer 30.0 SERPINA3 KIT CD34
14 sarcoma, synovial 29.9 SERPINA3 KIT CD34
15 malignant peripheral nerve sheath tumor 29.8 KIT CDKN2A CD34
16 fibrous histiocytoma 29.4 SERPINA3 KIT CD68 CD34 CD163
17 pseudosarcomatous fibromatosis 29.2 USP6 SERPINA3 CD68 CD34 AKTIP
18 plica syndrome 10.9
19 synovitis 10.9
20 bone giant cell sarcoma 10.4 CSF1 CD163
21 verruciform xanthoma of skin 10.4 SERPINA3 CD68
22 congenital epulis 10.4 SERPINA3 CD68
23 epulis 10.4 SERPINA3 CD68
24 tenosynovitis 10.4
25 lymphohistiocytoid mesothelioma 10.4 CDKN2A CD68
26 xanthogranulomatous pyelonephritis 10.4 SERPINA3 CD68
27 malignant inflammatory fibrous histiocytoma 10.4 SERPINA3 CD68
28 pancreas sarcoma 10.4 SERPINA3 CD68
29 primary cutaneous b-cell lymphoma 10.4 CDKN2B CDKN2A
30 xanthogranulomatous cholecystitis 10.4 SERPINA3 CD68
31 interdigitating dendritic cell sarcoma 10.4 SERPINA3 CD68
32 malignant giant cell tumor 10.4
33 hemosiderosis 10.4
34 chondroblastoma 10.4
35 spondylarthropathy 10.4 CSF1 CD163
36 cervical adenoid cystic carcinoma 10.3 KIT CDKN2A
37 langerhans cell sarcoma 10.3 CD68 CD163
38 melanoma-astrocytoma syndrome 10.3 CDKN2B CDKN2A
39 necrobiosis lipoidica 10.3 CD68 CD163
40 balloon cell malignant melanoma 10.3 CD68 CD163
41 hemangioma 10.3
42 laryngeal small cell carcinoma 10.3 KIT CDKN2A
43 chondrosarcoma 10.3
44 chromosomal triplication 10.3
45 rare soft tissue tumor 10.3
46 thyroid carcinoma 10.3
47 cutaneous solitary mastocytoma 10.3 SERPINA3 KIT
48 axillary lipoma 10.3 KIT CD68
49 type c thymoma 10.3 SERPINA3 KIT
50 small intestinal sarcoma 10.3 KIT CD68
51 male reproductive organ benign neoplasm 10.3 SERPINA3 CDKN2A
52 granulomatous dermatitis 10.3 CD68 CD163
53 inflammatory liposarcoma 10.3 CDKN2A CD34
54 histiocytic sarcoma 10.3 CDKN2A CD68 CD163
55 grade iii astrocytoma 10.3 SERPINA3 CDKN2B CDKN2A
56 leukoencephalopathy, hereditary diffuse, with spheroids 10.3 IL34 CSF1R CSF1
57 atypical neurofibroma 10.2 CDKN2A CD34
58 sclerosing hemangioma 10.2
59 lung sarcoma 10.2 SERPINA3 CD34
60 reticulohistiocytic granuloma 10.2 SERPINA3 CD68 CD163
61 langerhans cell histiocytosis 10.2 CSF1 CD68 CD163
62 cherubism 10.2 USP6 SERPINA3 CSF1
63 non-langerhans-cell histiocytosis 10.2 SERPINA3 CD68 CD163
64 noonan syndrome 1 10.2
65 neurofibromatosis 10.2
66 pseudo-turner syndrome 10.2
67 embryonal sarcoma 10.2 SERPINA3 KIT
68 skin sarcoma 10.2 CD68 CD34
69 malignant mesenchymoma 10.2 SERPINA3 CD34
70 glomeruloid hemangioma 10.2 CD68 CD34
71 low-grade astrocytoma 10.2 CDKN2B CDKN2A
72 chondroid lipoma 10.2 CD68 CD34
73 proliferative fasciitis 10.2 USP6 SERPINA3 CD68
74 core binding factor acute myeloid leukemia 10.2 KIT CSF1R
75 pulmonary artery leiomyosarcoma 10.2 CD68 CD34
76 omenn syndrome 10.2 SERPINA3 CSF1R CSF1
77 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 10.2 KIT CSF1R CSF1
78 pleomorphic liposarcoma 10.2 SERPINA3 KIT CDKN2A
79 adult malignant schwannoma 10.2 CDKN2A CD34
80 tonsil cancer 10.2 SERPINA3 KIT CDKN2A
81 extraosseous osteosarcoma 10.2 CD68 CD34
82 congenital granular cell tumor 10.2 CD68 CD34
83 oropharynx cancer 10.2 SERPINA3 KIT CDKN2A
84 leiomyosarcoma 10.2 SERPINA3 KIT CDKN2A
85 infiltrating angiolipoma 10.2 CDKN2A CD34
86 spinal cord sarcoma 10.2 KIT CD34
87 gallbladder leiomyoma 10.1 KIT CD34
88 malignant giant cell tumor of soft parts 10.1 CD68 CD34
89 small intestine leiomyosarcoma 10.1 KIT CD34
90 leukemia, acute lymphoblastic 3 10.1 CDKN2B CDKN2A CD34
91 deep leiomyoma 10.1 KIT CD34
92 mucocele of appendix 10.1 KIT CD34
93 reproductive organ benign neoplasm 10.1 SERPINA3 CDKN2A CD34
94 gastric liposarcoma 10.1 KIT CD34
95 gallbladder leiomyosarcoma 10.1 KIT CD34
96 skin melanoma 10.1 KIT CDKN2B CDKN2A
97 giant cell glioblastoma 10.1 SERPINA3 CDKN2A CD34
98 jejunal neoplasm 10.1 KIT CD34
99 plexiform schwannoma 10.1 KIT CD34
100 liver leiomyoma 10.1 KIT CD34
101 liposarcoma 10.1 CDKN2A CD68 CD34
102 colon leiomyosarcoma 10.1 KIT CD34
103 benign perivascular tumor 10.1 KIT CD34
104 osteogenic sarcoma 10.1
105 bone resorption disease 10.1
106 eumycotic mycetoma 10.1
107 osteoarthritis 10.1
108 47,xyy 10.1
109 precursor t-cell acute lymphoblastic leukemia 10.1 CDKN2B CDKN2A CD34
110 malignant fibrous histiocytoma 10.1 SERPINA3 KIT CD68
111 benign fibrous mesothelioma 10.1 KIT CD34
112 small intestine leiomyoma 10.1 KIT CD34
113 retroperitoneal leiomyosarcoma 10.1 KIT CD34
114 heart sarcoma 10.1 KIT CD34
115 mucositis 10.1
116 carpal tunnel syndrome 10.1
117 blau syndrome 10.1
118 triiodothyronine receptor auxiliary protein 10.1
119 tendinopathy 10.1
120 tendinitis 10.1
121 hypophosphatemia 10.1
122 osteomalacia 10.1
123 uveitis 10.1
124 frozen shoulder 10.1
125 glomus tumor 10.1
126 bursitis 10.1
127 extraskeletal chondroma 10.1
128 fasciitis 10.1
129 periostitis 10.1
130 enchondroma 10.1
131 oncogenic osteomalacia 10.1
132 pyogenic granuloma 10.1
133 paresthesia 10.1
134 hepatic angiomyolipoma 10.1 KIT CD34
135 ovarian angiosarcoma 10.1 SLC43A3 CD34
136 sarcomatoid squamous cell skin carcinoma 10.1 SERPINA3 CD68 CD34
137 malignant granular cell myoblastoma 10.1 SERPINA3 CD68 CD34
138 liver sarcoma 10.1 SERPINA3 CD68 CD34
139 cutaneous ganglioneuroma 10.1 KIT CD34
140 bartonellosis 10.1 CD68 CD34
141 polykaryocytosis inducer 10.1
142 sarcoidosis 1 10.1
143 thrombophilia due to thrombin defect 10.1
144 tuberous sclerosis 1 10.1
145 cryptorchidism, unilateral or bilateral 10.1
146 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
147 aneurysmal bone cysts 10.1
148 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
149 juvenile arthritis 10.1
150 lymphoma 10.1
151 pulmonary sarcoidosis 10.1
152 tuberous sclerosis 10.1
153 heel spur 10.1
154 spondylolysis 10.1
155 chondroma 10.1
156 synovium neoplasm 10.1
157 spindle cell sarcoma 10.1
158 juvenile rheumatoid arthritis 10.1
159 parotid gland cancer 10.1
160 rapidly involuting congenital hemangioma 10.1
161 avascular necrosis 10.1
162 pik3ca-related overgrowth syndrome 10.1
163 rare tumor 10.1
164 cutaneous fibrous histiocytoma 10.1 SERPINA3 CD68 CD34
165 salivary gland carcinoma 10.1 SERPINA3 KIT CDKN2A
166 cystic lymphangioma 10.1 SERPINA3 CD34
167 liver leiomyosarcoma 10.1 KIT CD34
168 esophageal tuberculosis 10.1 CD68 CD163
169 breast leiomyosarcoma 10.1 KIT CD34
170 skin benign neoplasm 10.1 SERPINA3 CD68 CD34
171 sarcomatous intrahepatic cholangiocarcinoma 10.0 KIT CD34
172 endobronchial leiomyoma 10.0 KIT CD34
173 retroperitoneal sarcoma 10.0 KIT CD34
174 prostate stromal sarcoma 10.0 KIT CD34
175 x-linked recessive disease 10.0 SERPINA3 CD68 CD34
176 glomangiomatosis 10.0 KIT CD34
177 intravascular fasciitis 10.0 USP6 CD68 CD34
178 gliosarcoma 10.0 SERPINA3 CDKN2A CD34
179 vaginal endometrial stromal sarcoma 10.0 KIT CD34
180 vulvar disease 10.0 KIT CDKN2A CD34
181 retroperitoneum carcinoma 10.0 KIT CDKN2A CD34
182 esophagus sarcoma 10.0 KIT CD34
183 fibrosarcoma of bone 10.0 SERPINA3 KIT CDKN2A CD68
184 breast malignant phyllodes tumor 10.0 SERPINA3 KIT CD34
185 polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1 10.0 IL34 CSF1R CSF1 CLU
186 heart cancer 10.0 SERPINA3 KIT CD34
187 mast cell neoplasm 10.0 SERPINA3 KIT CD34
188 mixed cell type cancer 10.0 SERPINA3 KIT CD34
189 hemangiopericytoma, malignant 10.0 SERPINA3 KIT CD34
190 synovium cancer 10.0 SERPINA3 KIT CD34
191 smooth muscle tumor 10.0 SERPINA3 KIT CD34
192 neurofibroma 9.9 KIT CDKN2A CD34
193 myxofibrosarcoma 9.9 SERPINA3 KIT CD34
194 skeletal muscle cancer 9.9 SERPINA3 KIT CD34
195 histiocytic and dendritic cell cancer 9.9 SERPINA3 CLU CD68 CD163
196 intestinal obstruction 9.9 SERPINA3 KIT CD34
197 germ cell and embryonal cancer 9.9 SERPINA3 KIT CD34
198 retroperitoneal hemangiopericytoma 9.9 KIT CD68 CD34
199 neurilemmoma 9.9 SERPINA3 KIT CD34
200 mediastinal cancer 9.9 KIT CD34
201 conventional fibrosarcoma 9.9 KIT CD68 CD34
202 blood coagulation disease 9.9 SERPINA3 KIT CD34
203 myeloid sarcoma 9.9 KIT CD68 CD34
204 angiosarcoma 9.9 KIT CD68 CD34
205 vagina sarcoma 9.9 KIT CD34
206 inflammatory myofibroblastic tumor 9.9 KIT CD68 CD34
207 integumentary system disease 9.9 SERPINA3 KIT CDKN2A
208 leukocyte disease 9.9 SERPINA3 KIT CD34
209 meningioma, familial 9.9 SERPINA3 CDKN2A CD68 CD34
210 epidermolytic acanthoma 9.9 CDKN2A CD68 CCR2
211 adult xanthogranuloma 9.9 SERPINA3 CD68 CD34 CD163
212 well-differentiated liposarcoma 9.8 SERPINA3 KIT CDKN2A CD34
213 pancreatic adenocarcinoma 9.8 KIT CSF1R CSF1 CDKN2B CDKN2A
214 dedifferentiated liposarcoma 9.8 SERPINA3 KIT CDKN2A CD34
215 peripheral nervous system neoplasm 9.8 SERPINA3 KIT CDKN2A CD34
216 cell type benign neoplasm 9.8 SERPINA3 KIT CDKN2A CD34
217 muscular disease 9.8 SERPINA3 KIT CD34
218 mesenchymal cell neoplasm 9.7 SERPINA3 KIT CD68 CD34
219 cardiovascular cancer 9.7 SERPINA3 KIT CD68 CD34
220 vascular cancer 9.7 SERPINA3 KIT CD68 CD34
221 meckel diverticulum 9.7 KIT CD34
222 neuroma 9.7 SERPINA3 KIT CD68 CD34
223 myofibroma 9.7 SERPINA3 CD34
224 follicular dendritic cell sarcoma 9.6 KIT CLU CD68 CD34
225 myeloma, multiple 9.6 SERPINA3 KIT CSF1 CDKN2A CD34
226 leukemia, acute lymphoblastic 9.6 KIT CSF1R CDKN2B CDKN2A CD34
227 malignant spindle cell melanoma 9.6 SERPINA3 KIT CDKN2A CD68 CD34
228 pancytopenia 9.6 SERPINA3 KIT CSF1 CD68 CD34
229 basal cell carcinoma 9.6 KIT CDKN2B CDKN2A CD68 CD34
230 connective tissue benign neoplasm 9.5 USP6 SERPINA3 KIT CD68 CD34
231 leber plus disease 9.5 SERPINA3 KIT CD68 CD34
232 hematologic cancer 9.4 SERPINA3 KIT CSF1R CSF1 CDKN2B CD34
233 dermatofibrosarcoma protuberans 9.4 SERPINA3 KIT COL6A3 CDKN2A CD34 CD163
234 leukemia, acute myeloid 9.2 SERPINA3 KIT CSF1R CSF1 CDKN2B CDKN2A
235 myelodysplastic syndrome 9.2 KIT CSF1R CSF1 CDKN2B CDKN2A CD68
236 acquired immunodeficiency syndrome 9.1 CD34 CD163 CCR2
237 myocardial infarction 8.8 SERPINA3 CLU CDKN2B CDKN2A CD34 CD163

Graphical network of the top 20 diseases related to Tenosynovial Giant Cell Tumor:



Diseases related to Tenosynovial Giant Cell Tumor

Symptoms & Phenotypes for Tenosynovial Giant Cell Tumor

MGI Mouse Phenotypes related to Tenosynovial Giant Cell Tumor:

45 (showing 8, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.17 AKTIP CCR2 CD163 CD34 CDKN2A CDKN2B
2 homeostasis/metabolism MP:0005376 10.15 AKTIP CCR2 CD163 CD34 CDKN2A CDKN2B
3 hematopoietic system MP:0005397 10.1 CCR2 CD163 CD34 CD68 CDKN2A CDKN2B
4 immune system MP:0005387 10.1 AKTIP CCR2 CD163 CD34 CD68 CDKN2A
5 integument MP:0010771 9.86 AKTIP CD34 CDKN2A CDKN2B CSF1 CSF1R
6 neoplasm MP:0002006 9.63 AKTIP CCR2 CD34 CDKN2A CDKN2B KIT
7 no phenotypic analysis MP:0003012 9.56 CCR2 CD68 CDKN2A CDKN2B CSF1 CSF1R
8 skeleton MP:0005390 9.23 AKTIP CCR2 CD68 CDKN2A COL6A3 CSF1

Drugs & Therapeutics for Tenosynovial Giant Cell Tumor

Drugs for Tenosynovial Giant Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 8, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sargramostim Approved, Investigational Phase 3 83869-56-1, 123774-72-1
2 Grapefruit Seed Extract Phase 2
3 Immunoglobulins Phase 1, Phase 2
4 Antibodies Phase 1, Phase 2
5
Paclitaxel Approved, Vet_approved Phase 1 33069-62-4 36314
6 Albumin-Bound Paclitaxel Phase 1
7 Tubulin Modulators Phase 1
8 Antimitotic Agents Phase 1

Interventional clinical trials:

(showing 12, show less)
# Name Status NCT ID Phase Drugs
1 A Double-blind, Randomized, Placebo-controlled Phase 3 Study of Orally Administered PLX3397 in Subjects With Pigmented Villonodular Synovitis or Giant Cell Tumor of the Tendon Sheath Active, not recruiting NCT02371369 Phase 3 Pexidartinib;Placebo
2 A Phase II Randomized, Double -Blind, Placebo Controlled Study to Assess Safety, Tolerability and Effect on Tumor Size of MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS) Completed NCT01643850 Phase 2 MCS110;Placebo
3 Phase II Study of Nilotinib Efficacy in Pigmented Villo-Nodular Synovitis/ Tenosynovial Giant Cell Tumour (PVNS/TGCT) Completed NCT01261429 Phase 2 Tasigna
4 A Multicenter Phase 1/2, Open-Label Study of DCC-3014 to Assess the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor Recruiting NCT03069469 Phase 1, Phase 2 DCC-3014
5 A PHASE 1B/2 OPEN-LABEL STUDY TO EVALUATE SAFETY, CLINICAL ACTIVITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF AVELUMAB (MSB0010718C) IN COMBINATION WITH OTHER CANCER IMMUNOTHERAPIES IN PATIENTS WITH ADVANCED MALIGNANCIES Recruiting NCT02554812 Phase 2 Avelumab;Utomilumab;PF-04518600;PD 0360324;CMP-001
6 A Phase 1/2 Study of Cabiralizumab, an Anti-CSF1 Receptor Antibody, in Patients With Pigmented Villonodular Synovitis (PVNS)/ Diffuse Type Tenosynovial Giant Cell Tumor (Dt-TGCT) Active, not recruiting NCT02471716 Phase 1, Phase 2
7 A Multi-Center Single Agent Phase II Study of the Efficacy of Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor Active, not recruiting NCT01207492 Phase 2 nilotinib
8 Open-Label, Multicenter, Dose Escalation Phase Ia/Ib Study With Expansion Phase to Evaluate Safety, Pharmacokinetics and Activity of RO5509554, Administered as an Intravenous Infusion as Monotherapy and in Combination With Paclitaxel in Patients With Advanced Solid Tumors Completed NCT01494688 Phase 1 Paclitaxel;RO5509554
9 A Phase 1 Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX73086 as a Single Agent in Subjects With Advanced Solid Tumors and in Subjects With Locally Advanced or Refractory Tenosynovial Giant Cell Tumor (TGCT) Terminated NCT02673736 Phase 1 PLX73086
10 A Phase 1 Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX7486 as a Single Agent in Patients With Advanced Solid Tumors Terminated NCT01804530 Phase 1 PLX7486 TsOH
11 An Open-label, Single-dose Study to Assess the Pharmacokinetics of Pexidartinib in Subjects With Moderate Hepatic Impairment Compared to Healthy Subjects Recruiting NCT04223635 Early Phase 1 Pexidartinib
12 A Disease Registry for Patients With Tenosynovial Giant Cell Tumors (TGCT), Also Known as Pigmented Villonodular Synovitis (PVNS) and Giant Cell Tumor of the Tendon Sheath (GCT-TS) Active, not recruiting NCT02948088

Search NIH Clinical Center for Tenosynovial Giant Cell Tumor

Genetic Tests for Tenosynovial Giant Cell Tumor

Anatomical Context for Tenosynovial Giant Cell Tumor

MalaCards organs/tissues related to Tenosynovial Giant Cell Tumor:

40
Bone, Breast, Brain, Thyroid, Salivary Gland

Publications for Tenosynovial Giant Cell Tumor

Articles related to Tenosynovial Giant Cell Tumor:

(showing 193, show less)
# Title Authors PMID Year
1
Management of Pigmented Villonodular Synovitis (PVNS): an Orthopedic Surgeon's Perspective. 61
32494892 2020
2
Pexidartinib for the treatment of adult symptomatic patients with tenosynovial giant cell tumors. 61
32478598 2020
3
Tenosynovial Giant Cell Tumor, Localized Type With Extensive Chondroid Metaplasia: A Case Report With Immunohistochemical and Molecular Genetic Analysis. 61
31771368 2020
4
Tenosynovial Giant Cell Tumor in the Hand: Experience with 173 Cases. 61
32312203 2020
5
PK/PD mediated dose optimization of emactuzumab, a CSF1R inhibitor, in patients with advanced solid tumors and diffuse-type tenosynovial giant cell tumor. 61
32575160 2020
6
Tenosynovial Giant Cell Tumor in an Infant. 61
32472881 2020
7
Shoulder Tumor/Tumor-Like Lesions: What to Look for. 61
32241665 2020
8
Tenosynovial giant cell tumor mimicking an ankle monoarthritis. 61
32384050 2020
9
Pexidartinib for the treatment of adult patients with symptomatic tenosynovial giant cell tumor: safety and efficacy. 61
32297819 2020
10
Tenosynovial Giant Cell Tumor of Temporomandibular Joint and Skull Base Presenting as Ear Canal Mass. 61
30955370 2020
11
Unusual manifestations of diffuse-type tenosynovial giant cell tumor in two patients: importance of radiologic-pathologic correlation. 61
31656976 2020
12
Soft Tissue Special Issue: Giant Cell-Rich Lesions of the Head and Neck Region. 61
31950466 2020
13
Uncommon tumors of temporomandibular joint: An institutional experience and review. 61
32040228 2020
14
Intraarticular Nodular Fasciitis of the Knee With MHY9-USP6 Fusion: A Case Report. 61
32089028 2020
15
A phase I study of pexidartinib, a colony-stimulating factor 1 receptor inhibitor, in Asian patients with advanced solid tumors. 61
30825104 2020
16
Monoarticular, Multifocal, Localized Tenosynovial Giant Cell Tumor of the Knee: A Case Report. 61
32044773 2020
17
Pexidartinib, a Novel Small Molecule CSF-1R Inhibitor in Use for Tenosynovial Giant Cell Tumor: A Systematic Review of Pre-Clinical and Clinical Development. 61
32440095 2020
18
Incomplete resection increases the risk of local recurrence and negatively affects functional outcome in patients with tenosynovial giant cell tumor of the hindfoot. 61
31839476 2019
19
KRAS mutant tenosynovial giant cell tumor in a pediatric patient: a case report. 61
31993359 2019
20
Massively parallel sequencing of tenosynovial giant cell tumors reveals novel CSF1 fusion transcripts and novel somatic CBL mutations. 61
31107544 2019
21
Molecular Profiling of Atypical Tenosynovial Giant Cell Tumors Reveals Novel Non-CSF1 Fusions. 61
31906059 2019
22
Risk Factors Associated With Postoperative Recurrence in Patients With Tenosynovial Giant Cell Tumor of the Hand: A Retrospective Cohort Study. 61
31524641 2019
23
Pexidartinib: First Approval. 61
31602563 2019
24
Long-term efficacy of imatinib mesylate in patients with advanced Tenosynovial Giant Cell Tumor. 61
31601938 2019
25
Tenosynovial giant cell tumor in the foot and ankle. 61
31526689 2019
26
The surgical outcome and recurrence rate of tenosynovial giant cell tumor in the elbow: a literature review. 61
31447124 2019
27
A Pregnant Woman With Multi-fragmented Giant Cell Tumor of Tendon Sheath: A Rare Anatomical Location. 61
31486673 2019
28
Diffuse-Type Tenosynovial Giant Cell Tumor of the Thoracic Spine: Appearance on FDG PET/CT. 61
31274627 2019
29
Histologically benign metastasizing tenosynovial giant cell tumor mimicking metastatic malignancy: A case report and review of literature. 61
31193787 2019
30
Surgical Treatment of Localized-Type Tenosynovial Giant Cell Tumors of Large Joints: A Study Based on a Multicenter-Pooled Database of 31 International Sarcoma Centers. 61
31318811 2019
31
Intra-articular fibroma-like perivascular epithelioid tumor (PEComa) mimicking tenosynovial giant cell tumor, diffuse type. 61
30206676 2019
32
Diffuse Tenosynovial Giant Cell Tumor Around the Temporomandibular Joint: An Entity With Special Radiologic and Pathologic Features. 61
30796908 2019
33
The effects of radiosynoviorthesis in pigmented villonodular synovitis of the knee. 61
30539286 2019
34
Diffuse-Type Tenosynovial Giant Cell Tumor of the Shoulder Evaluated by FDG PET/CT. 61
30624274 2019
35
Desmoplastic fibroblastoma mimicking tenosynovial giant cell tumor encasing a tendon of the foot. 61
30229348 2019
36
Diffuse-Type Tenosynovial Giant Cell Tumor of the Thoracic Spine: Appearance on FDG PET/CT. 61
30889006 2019
37
Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: a study protocol. 61
30738433 2019
38
Malignant Tenosynovial Giant Cell Tumor: The True "Synovial Sarcoma?" A Clinicopathologic, Immunohistochemical, and Molecular Cytogenetic Study of 10 Cases, Supporting Origin from Synoviocytes. 61
30206409 2019
39
Tenosynovial giant cell tumor of the cervical spine: a case report. 61
32094332 2019
40
The measurement of physical functioning among patients with Tenosynovial Giant Cell Tumor (TGCT) using the Patient-Reported Outcomes Measurement Information System (PROMIS). 61
30714073 2019
41
Giant Cell Poor Extra-Articular Diffuse-Type Tenosynovial Giant Cell Tumor With Extensive Desmin Expression: A Potential Diagnostic Pitfall With Cytogenetic Confirmation. 61
30019981 2019
42
Imaging features of phosphaturic mesenchymal tumors. 61
29987349 2019
43
Clinical and morphological correlations and histopathology of joint damage in patients with diffuse-type tenosynovial giant cell tumor. 61
32124739 2019
44
Tenosynovial giant cell tumor of the cervical spine: a case report. 61
31240119 2019
45
Expression of PD-L1 in mononuclear cells, multinucleated cells, and foam cells in tenosynovial giant cell tumors. 61
31933896 2019
46
Significance of incidental intra-articular and peri-articular FDG avid foci on PET/CT. 61
29665710 2019
47
A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. 61
31240240 2019
48
Concomitant Spondyloarthritis and Tenosynovial Giant Cell Tumor in Pigmented Villonodular Synovitis Challenging Cases. 61
30601200 2018
49
Extra-articular tenosynovial giant cell tumor of diffuse type in the temporal area with brain parenchymal invasion: a case report. 61
29334779 2018
50
Clinical characteristics and treatment outcomes in six cases of malignant tenosynovial giant cell tumor: initial experience of molecularly targeted therapy. 61
30594158 2018
51
Distinct extra-articular invasion patterns of diffuse pigmented villonodular synovitis/tenosynovial giant cell tumor in the knee joints. 61
29637236 2018
52
[Histopathological classification principles of rheumatic joint diseases : Contribution of pathology to the diagnosis]. 61
30255358 2018
53
Tenosynovial Giant Cell Tumor of the Clinoid: Rare Condition. 61
30026165 2018
54
Tenosynovial Giant Cell Tumors in Children: A Similar Entity Compared With Adults. 61
29494352 2018
55
Chondroid Tenosynovial Giant Cell Tumor of Temporomandibular Joint. 61
30693256 2018
56
Successful treatment of a diffuse type tenosynovial giant cell tumor in the thoracic spine mimicking spinal metastasis by frozen recapping laminoplasty in a patient with thyroid cancer. 61
29663145 2018
57
Hot shoulder PET/CT lesion: Unusual presentation of tenosynovial giant cell tumor. 61
29988775 2018
58
[CT imaging features of diffuse tenosynovial giant cell tumor of temporomandibular joint]. 61
29984929 2018
59
BILATERAL LOCALIZED PIGMENTED VILLONODULAR SYNOVITIS OF THE KNEE: CASE REPORT AND REVIEW. 61
30038543 2018
60
Intraarticular calcifying aponeurotic fibroma of the wrist: mimicking gout or calcium pyrophosphate dihydrate deposition disease. 61
29243144 2018
61
Bone Involvement Mimicking an Aggressive Bone Lesion in a Diffuse-type Tenosynovial Giant Cell Tumor in the Thoracic Vertebral Lamina: A Case Report. 61
30584508 2018
62
Burden of Illness Associated with Tenosynovial Giant Cell Tumors. 61
29580718 2018
63
[Diffuse-type tenosynovial giant cell tumor of the gluteus maximus muscle: a case report]. 61
29772865 2018
64
Pitfalls in the cytological diagnosis of tenosynovial giant cell tumor: An illustration of eight discordant cases. 61
28941190 2018
65
The Patient Perspective on the Impact of Tenosynovial Giant Cell Tumors on Daily Living: Crowdsourcing Study on Physical Function and Quality of Life. 61
29475829 2018
66
Clusterin in Neuroendocrine Epithelial Neoplasms: Absence of Expression in a Well-differentiated Tumor Suggests a Jejunoileal Origin. 61
29420353 2018
67
Locally Aggressive Connective Tissue Tumors. 61
29220303 2018
68
Articular abnormalities that may mimic arthritis. 61
30451404 2018
69
Tenosynovial Giant Cell Tumor in the Midfoot Treated With Femoral Head Allograft Reconstruction. 61
28864387 2018
70
Pigmented villonodular synovitis. 61
30745604 2018
71
Tenosynovial giant cell tumor: case report of a patient effectively treated with pexidartinib (PLX3397) and review of the literature. 61
30002809 2018
72
Tenosynovial Giant Cell Tumor: Incidence, Prevalence, Patient Characteristics, and Recurrence. A Registry-based Cohort Study in Denmark. 61
28765257 2017
73
Chondroid Tenosynovial Giant Cell Tumor of the Temporomandibular Joint: A Rare Case Report. 61
29215692 2017
74
Fine needle aspiration cytology diagnosis of metastatic malignant diffuse type tenosynovial giant cell tumor. 61
28701836 2017
75
Prognosis of Advanced Tenosynovial Giant Cell Tumor of the Knee Diagnosed During Total Knee Arthroplasty. 61
28161138 2017
76
Imaging features for diffuse-type tenosynovial giant cell tumor of the temporomandibular joint: A case report. 61
28658169 2017
77
Malignant tenosynovial giant cell tumor with CDKN2A/B genomic alteration: a histological, immunohistochemical, and molecular study. 61
27989786 2017
78
Structural, spectroscopic and molecular docking studies on 2-amino-3-chloro-5-trifluoromethyl pyridine: A potential bioactive agent. 61
28012392 2017
79
Localized and diffuse forms of tenosynovial giant cell tumor (formerly giant cell tumor of the tendon sheath and pigmented villonodular synovitis). 61
28057477 2017
80
Pigmented Villonodular Synovitis - Various Manifestations, Inconsistent Terminology and Treatment. Cases Study. 61
28436371 2017
81
Fine Needle Aspiration Cytology of Diffuse-Type Tenosynovial Giant Cell Tumors. 61
28324880 2017
82
Extra-articular diffuse-type tenosynovial giant cell tumor with benign histological features resulting in fatal pulmonary metastases. 61
28219303 2017
83
Coexisting sarcoidal granulomatous inflammation and diffuse tenosynovial giant cell tumor of the knee after a total knee replacement: a case report. 61
27717976 2016
84
[Diagnosis and treatment of diffuse tenosynovial giant cell tumor arising from temporomandibular joints]. 61
27987512 2016
85
MR Imaging and US of the Wrist Tendons. 61
27726753 2016
86
Intramuscular Tenosynovial Giant Cell Tumor, Diffuse-Type. 61
26755356 2016
87
Pediatric Intra-Articular Localized Tenosynovial Giant Cell Tumor Presenting as an Acutely Irritable Hip: A Case Report. 61
29252637 2016
88
Diffuse Type Tenosynovial Giant Cell Tumor of the Ankle. 61
26996490 2016
89
Tenosynovial giant cell tumors in unusual locations detected by positron emission tomography imaging confused with malignant tumors: report of two cases. 61
27113721 2016
90
Patient-reported Symptoms of Tenosynovial Giant Cell Tumors. 61
27041409 2016
91
Magnetic resonance imaging of Hoffa's fat pad and relevance for osteoarthritis research: a narrative review. 61
26455999 2016
92
Current Systemic Treatment Options for Tenosynovial Giant Cell Tumor/Pigmented Villonodular Synovitis: Targeting the CSF1/CSF1R Axis. 61
26820289 2016
93
[Diffuse tenosynovial giant cell tumor of the cervical spine destroying vertebra C6 - a case report]. 61
27869449 2016
94
Tenosynovial Giant Cell Tumor in the Dermis of the External Auditory Meatus. 61
27072732 2016
95
Arthroscopic Resection of a Tenosynovial Giant Cell Tumor in the Wrist: A Case Report. 61
26496348 2015
96
Diffuse-type giant cell tumor of the tendon sheath in the temporal region incidentally diagnosed due to a temporal tumor: A report of two cases and review of the literature. 61
26622648 2015
97
Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor. 61
26222558 2015
98
Tenosynovial Giant Cell Tumor, Diffuse Type/Pigmented Villonodular Synovitis in a Pars Defect: A Case Report. 61
26067150 2015
99
Fine Needle Aspiration Cytology of Chondroid Tenosynovial Giant Cell Tumor of the Hand. 61
26266013 2015
100
Tenosynovial, diffuse type giant cell tumor of the temporomandibular joint, diagnosis and management of a rare tumor. 61
25699124 2015
101
[ARTHROSCOPIC RESECTION OF BENIGN TUMOR IN THE KNEE POSTERIOR SEPTUM]. 61
26455191 2015
102
Intra-articular tenosynovial giant cell tumor arising from the posterior cruciate ligament. 61
26337311 2015
103
Tenosynovial giant cell tumor arising from the posterior cruciate ligament: a case report and literature review. 61
26261570 2015
104
Malignant tenosynovial giant cell tumor of the leg: a radiologic-pathologic correlation and review of the literature. 61
25861547 2015
105
Multiple metastases from histologically benign intraarticular diffuse-type tenosynovial giant cell tumor: a case report. 61
25130396 2014
106
Hepatoid tenosynovial giant cell tumor - a rare morphologic variant case report. 61
25023880 2014
107
Tenosynovial giant cell tumor presenting as a parotid gland mass: Expanding the differential diagnosis of giant cell-rich lesions in salivary glands. 61
25745294 2014
108
Diffuse-type tenosynovial giant cell tumor with t(1;17)(p13;p13) and trisomy 5. 61
25189912 2014
109
Tenosynovial Giant Cell Tumor of Diffuse Type Mimicking Bony Metastasis Detected on F-18 FDG PET/CT. 61
25177381 2014
110
Intramuscular diffuse-type tenosynovial giant cell tumor of the deltoid muscle in a child. 61
24676801 2014
111
A tenosynovial giant cell tumor arising from femoral attachment of the anterior cruciate ligament. 61
24900909 2014
112
Soft tissue angiofibroma: a case report. 61
24113908 2014
113
Partial response of a rare malignant metastatic diffuse tenosynovial giant cell tumor with benign histologic features, treated with SCH 717-454, an insulin growth factor receptor inhibitor, in combination with everolimus, an MTOR inhibitor. 61
23430345 2014
114
Recurrent temporal bone tenosynovial giant cell tumor with chondroid metaplasia: the use of imaging to assess recurrence. 61
24571839 2014
115
Primary diffuse-type tenosynovial giant cell tumor of the spine: a report of 3 cases and systemic review of the literature. 61
25269059 2014
116
Localized giant cell tenosynovial tumor seen in the knee joint. 61
24716065 2014
117
Next generation sequencing-based expression profiling identifies signatures from benign stromal proliferations that define stromal components of breast cancer. 61
24342436 2013
118
Chondroid tenosynovial giant cell tumor of the temporal bone. 61
23303171 2013
119
Intra-articular synovial sarcoma. 61
23455705 2013
120
Tenosynovial giant cell tumor in an unusual localization. 61
23619549 2013
121
Tenosynovial giant cell tumor arising on the scapular region. 61
24403889 2013
122
Bilateral cadaveric Achilles tendon graft in reconstruction after Achilles tendon tumor resection. 61
22857848 2013
123
Long-term outcome of the treatment of high-risk tenosynovial giant cell tumor/pigmented villonodular synovitis with radiotherapy and surgery. 61
22281719 2012
124
Histology-specific therapy for advanced soft tissue sarcoma and benign connective tissue tumors. 61
22610342 2012
125
Tenosynovial giant cell tumor: case report and review. 61
22849738 2012
126
Malignant diffuse-type tenosynovial giant cell tumor of the buttock. 61
22827766 2012
127
Intra-articular tenosynovial giant cell tumor arising from the posterior cruciate ligament. 61
22784912 2012
128
Efficacy of imatinib mesylate for the treatment of locally advanced and/or metastatic tenosynovial giant cell tumor/pigmented villonodular synovitis. 61
21823110 2012
129
Navigation-guided resection for a tenosynovial giant cell tumor involving the temporomandibular joint and skull base. 61
22421861 2012
130
Bilateral tenosynovial giant cell tumor of the knee accompanied by chronic ACL tear. 61
21590297 2012
131
Tenosynovial giant cell tumor in the cervico-thoracic junction. 61
23208911 2012
132
Selected Lesions Featuring Giant Cells. 61
26837653 2011
133
Treatment of tenosynovial giant cell tumor and pigmented villonodular synovitis. 61
21577109 2011
134
Tenosynovial giant cell tumor of the thigh: positron emission tomography findings. 61
21869945 2011
135
Chondroid tenosynovial giant cell tumor: a clinicopathological and immunohistochemical analysis of 5 new cases. 61
21087985 2011
136
Localized tenosynovial giant cell tumor in both knee joints. 61
20354849 2010
137
[The diffuse-type tenosynovial giant cell tumor in ankle joint: a case report]. 61
20701140 2010
138
Translating gene expression into clinical care: sarcomas as a paradigm. 61
20194847 2010
139
Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor. 61
20981142 2010
140
Giant cell tumor of the tendon sheath in the knee of an 11-year-old girl. 61
20103492 2010
141
Tenosynovial giant cell tumors as accidental findings after episodes of distortion of the ankle: two case reports. 61
20062758 2009
142
Cytogenetic analysis of a primary bone angiosarcoma. 61
19737647 2009
143
Clusterin is expressed in normal synoviocytes and in tenosynovial giant cell tumors of localized and diffuse types: diagnostic and histogenetic implications. 61
19542874 2009
144
Yellow nodule on the distal finger. Xanthomatous localized tenosynovial giant cell tumor (TGCT) of the finger. 61
19687429 2009
145
The macrophage colony-stimulating factor 1 response signature in breast carcinoma. 61
19188147 2009
146
Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation. 61
18829481 2008
147
Tenosynovial giant cell tumor of the posterior arch of C1. 61
18309482 2008
148
Complete response to imatinib in relapsing pigmented villonodular synovitis/tenosynovial giant cell tumor (PVNS/TGCT). 61
18296418 2008
149
Malignant diffuse-type tenosynovial giant cell tumors: a series of 7 cases comparing with 24 benign lesions with review of the literature. 61
18301053 2008
150
[Diagnostic spectrum of synovitis]. 61
18210134 2008
151
Infiltration of the pes anserinus complex by an extraarticular diffuse-type giant cell tumor (D-TGCT). 61
17450371 2008
152
Tenosynovial giant cell tumor and pigmented villonodular synovitis. 61
17579851 2007
153
Translocation and expression of CSF1 in pigmented villonodular synovitis, tenosynovial giant cell tumor, rheumatoid arthritis and other reactive synovitides. 61
17527089 2007
154
Tenosynovial giant cell tumor and pigmented villonodular synovitis: a proposal for unification of these clinically distinct but histologically and genetically identical lesions. 61
17225151 2007
155
Diffuse-type giant cell tumor of the subcutaneous thigh. 61
16565836 2007
156
[Differential diagnosis of chronic synovitis]. 61
17031677 2006
157
Atypical tenosynovial giant cell tumor of the extensor hallucis longus tendon. 61
16868332 2006
158
Diffuse-type tenosynovial giant cell tumor in association with neurofibromatosis type 1-Noonan syndrome: possibly more than a chance relationship. 61
16723851 2006
159
A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells. 61
16407111 2006
160
Conditions suggesting lymphoma: case 3. Primary synovial lymphoma with osteoclast-like giant cells presenting as a tenosynovial giant-cell tumor. 61
15923579 2005
161
[A case of diffuse tenosynovial giant cell tumor of the temporal bone]. 61
16229192 2005
162
Chemical-shift micro-imaging of subcutaneous lesions. 61
15711849 2005
163
[Tenosynovial giant cell tumor]. 61
15657685 2005
164
Molecular cytogenetic characterization of tenosynovial giant cell tumors. 61
15548367 2004
165
A large, multiply recurrent tenosynovial giant cell tumor of the hand treated with resection and radiation therapy. 61
15074461 2004
166
Arthroscopic resection of an extra-articular tenosynovial giant cell tumor from the ankle region. 61
12966401 2003
167
[Case report: Tenosynovial giant cell tumor arising from the knee joint]. 61
14661299 2003
168
Molecular cytogenetic mapping of recurrent chromosomal breakpoints in tenosynovial giant cell tumors. 61
12447678 2002
169
[Diagnosis and therapy of nodular tenosynovitis of the tendon sheath--case presentation]. 61
12219636 2002
170
Osteomalacia cured by surgery. 61
11836086 2002
171
[Giant cell tenosynovial tumor, spread in the forearm soft tissues. A case report]. 61
11496611 2001
172
Fibrous histiocytoma of tendon sheath of the hand. 61
11133056 2000
173
Pigmented villonodular synovitis secondary to laceration of the perforating branch of the peroneal artery. 61
11012988 2000
174
[Benign tenosynovial giant cell tumor in the region of the upper ankle joint. A rare differential diagnosis of a soft tissue tumor of the foot]. 61
10925651 2000
175
Localized tenosynovial giant cell tumor of tendon sheath. A case report. 61
10834013 2000
176
Diffuse-type giant cell tumor: clinicopathologic and immunohistochemical analysis of 50 cases with extraarticular disease. 61
10757395 2000
177
Giant cell tumor of tendon sheath, tenosynovial giant cell tumor, and pigmented villonodular synovitis: defining the presentation, surgical therapy and recurrence. 61
10671695 2000
178
Tenosynovial giant cell tumor of finger, localized type: a case report. 61
10642950 1999
179
Analysis of 35 cases of localized and diffuse tenosynovial giant cell tumor: a report from the Chromosomes and Morphology (CHAMP) study group. 61
10392632 1999
180
Tenosynovial giant cell tumors: evidence for a desmin-positive dendritic cell subpopulation. 61
9796719 1998
181
Diffuse variant tenosynovial giant cell tumor of the temporomandibular joint: report of a case. 61
9710197 1998
182
Sclerosing perineurioma: a clinicopathologic study of 19 cases of a distinctive soft tissue lesion with a predilection for the fingers and palms of young adults. 61
9414186 1997
183
Cytologic findings in tenosynovial giant cell tumors investigated by fine-needle aspiration cytology. 61
9143824 1997
184
Tenosynovial giant-cell tumor arising from the anterior cruciate ligament of the knee. 61
8864010 1996
185
MRI of giant cell tumor of the tendon sheath in the cervical spine. 61
8576459 1996
186
Diffuse tenosynovial giant cell tumor of soft tissues. Report of a case with cytologic and cytogenetic findings. 61
7631554 1995
187
Tenosynovial giant-cell tumor in the knee joint. 61
7794435 1995
188
Diffuse-variant tenosynovial giant cell tumor: a rare and aggressive lesion. 61
8163276 1994
189
Scintigraphic evaluation of tenosynovial giant-cell tumor using technetium-99m(V)-dimercaptosuccinic acid. 61
8410292 1993
190
Diffuse type tenosynovial giant cell tumor of the ankle. 61
8386232 1993
191
Tenosynovial giant-cell tumor of the cervical spine. Case report. 61
1331365 1992
192
Diffuse and localized tenosynovial giant cell tumor and pigmented villonodular synovitis: a clinicopathologic and flow cytometric DNA analysis. 61
1319390 1992
193
[Tenosynovial giant cell tumor in the differential diagnosis of painful heel]. 61
2237042 1990

Variations for Tenosynovial Giant Cell Tumor

Expression for Tenosynovial Giant Cell Tumor

Search GEO for disease gene expression data for Tenosynovial Giant Cell Tumor.

Pathways for Tenosynovial Giant Cell Tumor

GO Terms for Tenosynovial Giant Cell Tumor

Cellular components related to Tenosynovial Giant Cell Tumor according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 CSF1-CSF1R complex GO:1990682 8.62 CSF1R CSF1

Biological processes related to Tenosynovial Giant Cell Tumor according to GeneCards Suite gene sharing:

(showing 13, show less)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.8 KIT IL34 CSF1 CLU CDKN2A CD34
2 cytokine-mediated signaling pathway GO:0019221 9.77 KIT IL34 CSF1R CSF1 CCR2
3 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.7 KIT CSF1R CSF1
4 negative regulation of phosphorylation GO:0042326 9.51 CDKN2B CDKN2A
5 inflammatory response GO:0006954 9.5 SERPINA3 KIT IL34 CSF1R CSF1 CD163
6 positive regulation of macrophage differentiation GO:0045651 9.49 IL34 CSF1
7 positive regulation of monocyte differentiation GO:0045657 9.48 IL34 CSF1
8 somatic stem cell division GO:0048103 9.46 KIT CDKN2A
9 hemopoiesis GO:0030097 9.46 KIT CSF1R CD34 CCR2
10 positive regulation of macrophage proliferation GO:0120041 9.43 IL34 CSF1R
11 positive regulation of macrophage chemotaxis GO:0010759 9.43 IL34 CSF1R CSF1
12 macrophage colony-stimulating factor signaling pathway GO:0038145 9.4 CSF1R CSF1
13 microglial cell proliferation GO:0061518 8.92 IL34 CSF1R CSF1 CLU

Molecular functions related to Tenosynovial Giant Cell Tumor according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861 9.16 CDKN2B CDKN2A
2 cytokine binding GO:0019955 9.13 KIT CSF1R CCR2
3 macrophage colony-stimulating factor receptor binding GO:0005157 8.62 IL34 CSF1

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