MCID: TNS014
MIFTS: 36

Tenosynovitis

Categories: Bone diseases, Muscle diseases

Aliases & Classifications for Tenosynovitis

MalaCards integrated aliases for Tenosynovitis:

Name: Tenosynovitis 12 44 15 63 73
Inflammation of Tendon Sheath 12

Classifications:



External Ids:

Disease Ontology 12 DOID:970
MeSH 44 D013717
SNOMED-CT 68 67801009
UMLS 73 C0039520

Summaries for Tenosynovitis

MalaCards based summary : Tenosynovitis, also known as inflammation of tendon sheath, is related to synovitis and bursitis. An important gene associated with Tenosynovitis is LHB (Luteinizing Hormone Beta Polypeptide). The drugs Lidocaine and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and liver.

Wikipedia : 76 Tenosynovitis is the inflammation of the fluid-filled sheath (called the synovium) that surrounds a... more...

Related Diseases for Tenosynovitis

Diseases related to Tenosynovitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 synovitis 31.6 COMP CRP
2 bursitis 30.7 CRP MRAP
3 calcific tendinitis 30.3 CRP LHB
4 arthropathy 29.8 COMP CRP
5 tendinitis 29.6 AKTIP COMP CRP LHB MRAP
6 reactive arthritis 29.6 COMP CRP
7 psoriatic arthritis 29.6 COMP CRP TNFRSF1B
8 juvenile rheumatoid arthritis 29.4 CRP TNFRSF1B
9 bone inflammation disease 29.3 COMP CRP MRAP TNFRSF1B
10 transient arthritis 29.3 COMP MRAP TNFRSF1B
11 vasculitis 29.2 CRP TNFRSF1B
12 bicipital tenosynovitis 12.5
13 nodular tenosynovitis 12.3
14 tenosynovitis of foot and ankle 12.0
15 de quervain disease 11.8
16 overuse syndrome 11.4
17 pigmented villonodular synovitis 11.4
18 gonococcal synovitis 11.3
19 repetitive motion disorders 11.1
20 repetitive stress injuries 11.1
21 cumulative trauma disorders 11.1
22 arthritis 10.8
23 rheumatoid arthritis 10.6
24 carpal tunnel syndrome 10.4
25 mononeuropathy of the median nerve, mild 10.4
26 mycobacterium marinum 10.3
27 osteomyelitis 10.2
28 septic arthritis 10.2
29 mycobacterium kansasii 10.2
30 salpingitis 10.2 AKTIP CRP
31 discitis 10.2 CRP MRAP
32 aortitis 10.1 CRP MRAP
33 pyuria 10.1 CRP MRAP
34 mesenteric lymphadenitis 10.1 CRP MRAP
35 renal tuberculosis 10.1 CRP MRAP
36 systemic lupus erythematosus 10.1
37 epicondylitis 10.1
38 giant cell tumor 10.1
39 lupus erythematosus 10.1
40 cartilage disease 10.1 COMP CRP
41 relapsing polychondritis 10.1 COMP CRP
42 osteoarthritis 10.1
43 frozen shoulder 10.1
44 spondylitis 10.0 CRP TNFRSF1B
45 tendinopathy 10.0
46 histoplasmosis 10.0
47 dermatitis 10.0
48 fasciitis 10.0
49 miliary tuberculosis 10.0
50 villonodular synovitis 10.0

Graphical network of the top 20 diseases related to Tenosynovitis:



Diseases related to Tenosynovitis

Symptoms & Phenotypes for Tenosynovitis

Drugs & Therapeutics for Tenosynovitis

Drugs for Tenosynovitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 103)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 137-58-6 3676
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3 1177-87-3
3
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3 50-02-2 5743
5
Racepinephrine Approved Phase 4 329-65-7 838
6
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
7
Prednisone Approved, Vet_approved Phase 4,Phase 3 53-03-2 5865
8
Sulfasalazine Approved Phase 4,Not Applicable 599-79-1 5353980 5359476
9
Methotrexate Approved Phase 4,Phase 2,Not Applicable 59-05-2, 1959-05-2 126941
10
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
11
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
12
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3 302-25-0
13
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
14
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3 2921-57-5
15
leucovorin Approved Phase 4,Phase 2 58-05-9 6006 143
16
Leflunomide Approved, Investigational Phase 4 75706-12-6 3899
17
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 59-30-3 6037
18
Prednisolone hemisuccinate Experimental Phase 4,Phase 3 2920-86-7
19 Sodium Channel Blockers Phase 4,Not Applicable
20 Central Nervous System Depressants Phase 4,Not Applicable
21 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
22 Anti-Arrhythmia Agents Phase 4,Not Applicable
23 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2
24 Immunologic Factors Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
25 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Not Applicable
26 Anesthetics, Local Phase 4,Not Applicable
27 Diuretics, Potassium Sparing Phase 4,Not Applicable
28 Anesthetics Phase 4,Not Applicable
29 Protective Agents Phase 4,Early Phase 1
30 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
31 Adrenergic Agonists Phase 4
32 Sympathomimetics Phase 4
33 triamcinolone acetonide Phase 4
34 Gastrointestinal Agents Phase 4,Phase 3
35 Triamcinolone diacetate Phase 4
36 Epinephryl borate Phase 4
37 HIV Protease Inhibitors Phase 4,Phase 3
38 Triamcinolone hexacetonide Phase 4
39 Anti-Asthmatic Agents Phase 4
40 Adrenergic beta-Agonists Phase 4
41 Hormone Antagonists Phase 4,Phase 3
42 glucocorticoids Phase 4,Phase 3
43 Adrenergic alpha-Agonists Phase 4
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
45
protease inhibitors Phase 4,Phase 3
46 Vasoconstrictor Agents Phase 4
47 Neurotransmitter Agents Phase 4
48 BB 1101 Phase 4,Phase 3
49 Autonomic Agents Phase 4,Phase 3
50 Antiemetics Phase 4,Phase 3

Interventional clinical trials:

(show all 43)
# Name Status NCT ID Phase Drugs
1 Long Term Effectiveness of Trigger Finger Injections With Triamcinolone vs. Dexamethasone Completed NCT03641508 Phase 4 Triamcinolone;Dexamethasone
2 Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients Completed NCT01169597 Phase 4 prednisone
3 Aiming for Remission in Rheumatoid Arthritis (RA) - the ARCTIC Trial Completed NCT01205854 Phase 4
4 Ultrasound-guided Injection for DeQuervain's Recruiting NCT02038634 Phase 4 Betamethasone
5 Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone Recruiting NCT03704584 Phase 4 Treatment Group (corticosteroid injection plus lidocaine);Control Group (corticosteroid alone)
6 Filling Bone Erosions: a Longitudinal Multicentric HR-pQCT Study of Subcutaneous Tocilizumab in Rheumatoid Arthritis Recruiting NCT02765074 Phase 4 subcutaneous tocilizumab
7 Efficacy, Radiographic and Laboratory Changes in Refractory Rheumatoid Arthritis Patients Treated With H.P. Acthar Gel Recruiting NCT03082573 Phase 4 H.P. Acthar gel
8 A Study to Evaluate the Impact of Apremilast (CC-10004) on MRI Outcomes in Subjects With Psoriatic Arthritis Not yet recruiting NCT03783026 Phase 4 CC-10004
9 Comparison of the Efficacy of Corticosteroid Injection and ESWT in Patients With CTS Not yet recruiting NCT03792945 Phase 4 local injection
10 Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study Terminated NCT01659242 Phase 4 Methotrexate plus sulfasalazine;Leflunomide
11 Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia Unknown status NCT02778906 Phase 3 Abatacept;Placebo
12 Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3 diclofenac sodium;Matching Placebo
13 Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders Recruiting NCT02266433 Phase 3 Ketorolac;Dexamethasone
14 Abatacept in earLy Onset Polymyalgia Rheumatica: Study ALORS Active, not recruiting NCT03632187 Phase 3 Abatacept;Placebos
15 Corticosteroid vs. Amniotic Fluid Injections in Patients With Trigger Finger Enrolling by invitation NCT03583151 Phase 3
16 Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder Terminated NCT00876317 Phase 3 Etoricoxib 60 mg;Etoricoxib 90 mg
17 Abatacept for SLE Arthritis (IM101-330) Unknown status NCT02429934 Phase 1, Phase 2 abatacept;Placebo
18 Tocilizumab Effect iN pOlymyalgia Rheumatica Completed NCT01713842 Phase 2 TCZ
19 Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care Recruiting NCT03371251 Phase 1, Phase 2 BOS161721;Placebo
20 A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate Withdrawn NCT02097264 Phase 2 NNC0109-0012;Adalimumab;placebo
21 Study Comparing One Versus Two Cortisone Injections for Trigger Finger Unknown status NCT00951236 Not Applicable One cortisone injection;Two cortisone Injections
22 Treatment of Trigger Finger With Steroid Injection Versus Steroid Injection and Splinting Unknown status NCT01886157 Not Applicable
23 Treatment of Insertional Achilles Tendinopathy by Hyaluronic Acid Injection Unknown status NCT02368561 Early Phase 1 Injection of Hyaluronic Acid -" SYNVISC" (hylan G-F 20)
24 Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients Unknown status NCT03000205 Not Applicable
25 Musculoskeletal Pathologies of the Upper Extremity in Surgical Device Mechanics Unknown status NCT03014128
26 A Clinical Trial of Splinting for DeQuervain's Tenosynovitis Completed NCT00438191
27 The Natural History of Congenital Trigger Thumbs Completed NCT01424995
28 A Case Control Study to Define Clinical, Immunologic and Radiographic Features of the Aromatase Inhibitor Arthralgia Syndrome Completed NCT00890058
29 Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis Completed NCT02780999 Not Applicable
30 Study of Open and Percutaneous Release of Acquired Trigger Thumb Completed NCT03679793 Not Applicable
31 Comparison of the Clinical Examination and the Joint Ultrasonography in Lupus Patients Completed NCT02922114 Not Applicable
32 Study With Etanercept Focusing on Remission and Predictability of Remission in Real Life Clinical Practice Completed NCT02202837 etanercept;etanercept
33 Ultrasound Findings of Finger, Wrist and Knee Joints in Mucopolysaccharidosis Completed NCT02067650
34 Biomarkers of Remission in Rheumatoid Arthritis (BioRRA) Completed NCT02219347 Not Applicable DMARD cessation
35 Ultrasound-guided Intervention and Hand Tenosynovitis in Patients With Diabetes Mellitus Recruiting NCT03789526 Not Applicable
36 The Treatment of Purulent Flexor Tenosynovitis Recruiting NCT02320929 Not Applicable
37 Sinew Acupuncture for de Quervain's Tenosynovitis Recruiting NCT03472443 Not Applicable
38 Effectiveness of Astym Treatment For de Quervain's Tenosynovitis Recruiting NCT02442622 Not Applicable
39 Disparity Between Ultrasound- and Clinical Findings in Psoriatic Arthritis in Remission Recruiting NCT03396679
40 A Prospective Study Comparing Suture Anchor and Soft Tissue Pectoralis Major Tendon Techniques for Biceps Tenodesis Recruiting NCT03529162 Not Applicable
41 Prospective Study of Patients With Rheumatoid Arthritis After the Age of 65 Recruiting NCT02686320
42 Prediction of Erosive Disease in Early Rheumatoid Arthritis (RA) by Ultrasound and Cartilage Biodegradation Markers Not yet recruiting NCT02464384 Not Applicable
43 Rheumatoid Arthritis Response to Methotrexate Not yet recruiting NCT03535519 Methotrexate

Search NIH Clinical Center for Tenosynovitis

Cochrane evidence based reviews: tenosynovitis

Genetic Tests for Tenosynovitis

Anatomical Context for Tenosynovitis

MalaCards organs/tissues related to Tenosynovitis:

41
Bone, Skin, Liver, Testes, Kidney, Heart, Tonsil

Publications for Tenosynovitis

Articles related to Tenosynovitis:

(show top 50) (show all 1004)
# Title Authors Year
1
Cost-Effective Management of Stenosing Tenosynovitis. ( 29891265 )
2018
2
Reply to "MRI in de Quervain Tenosynovitis: Is Making the Diagnosis Sufficient?" ( 29469623 )
2018
3
MRI in De Quervain Tenosynovitis: Is Making the Diagnosis Sufficient? ( 29469625 )
2018
4
Tenosynovitis caused by Mycobacterium malmoense in two kidney transplant recipients and review of the literature. ( 29125666 )
2018
5
Nodular Tenosynovitis of the Temporomandibular Joint: An Entity Not Yet Described. ( 29762327 )
2018
6
A Rare Cause of Pyogenic Flexor Tenosynovitis: Nocardia nova. ( 29352602 )
2018
7
Lipoma arborescens-a rare cause of bilateral ankle tenosynovitis. ( 29351664 )
2018
8
Gonococcal Tenosynovitis Diagnosed with the Aid of Emergency Department Bedside Ultrasound. ( 29685466 )
2018
9
Chronic Tenosynovitis due to <i>Mycobacteria kansasii</i> in an Immunocompetent Host. ( 29850302 )
2018
10
Usefulness of ultrasound for the diagnosis of pyogenic flexor tenosynovitis: A prospective single-center study of 57 cases. ( 29396150 )
2018
11
Results of surgical treatment of De Quervain's tenosynovitis: 80 cases with a mean follow-up of 9.5 years. ( 29909297 )
2018
12
Ultrasound for the diagnosis of pyogenic flexor tenosynovitis. ( 29759904 )
2018
13
Ultrasonography for diagnosis, monitoring and treatment of tenosynovitis in patients with rheumatoid arthritis. ( 29510818 )
2018
14
Tuberculous tenosynovitis of the flexor tendons of the wrist: a case report. ( 29636100 )
2018
15
The predictive role of ultrasound-detected tenosynovitis and joint synovitis for flare in patients with rheumatoid arthritis in stable remission. Results of an Italian multicentre study of the Italian Society for Rheumatology Group for Ultrasound: the STARTER study. ( 29886430 )
2018
16
Infectious flexor hand tenosynovitis: State of knowledge. A study of 120 cases. ( 29881224 )
2018
17
'Deep Koebner' phenomenon of the flexor tendon-associated accessory pulleys as a novel factor in tenosynovitis and dactylitis in psoriatic arthritis. ( 29511028 )
2018
18
The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development. ( 29618136 )
2018
19
Tenosynovitis with Rice Body Formation Due to Mycobacterium Intracellulare Infection After Initiation of Infliximab Therapy. ( 29875354 )
2018
20
<i>Histoplasma</i> Tenosynovitis Revealed by Fungal Culture in a Patient Treated with Infliximab. ( 29419449 )
2018
21
Proximal linear extension of skin hypopigmentation after ultrasound-guided corticosteroid injection for de Quervain tenosynovitis: A Case Report. ( 29355747 )
2018
22
Kingella kingae hand and wrist tenosynovitis in young children. ( 29587602 )
2018
23
Asymetric red-blue hypertrophic hand and tenosynovitis due to acrodermatitis chronica atrophicans. ( 30239931 )
2018
24
Automatic quantification of tenosynovitis on MRI of the wrist in patients with early arthritis: a feasibility study. ( 30421014 )
2018
25
Imaging detected tenosynovitis of metacarpophalangeal and wrist joints: an increasingly recognised characteristic of rheumatoid arthritis. ( 30296973 )
2018
26
Nodular skin lesion secondary to Mycobacterium abscessus tenosynovitis. ( 30016487 )
2018
27
Myelitis and tenosynovitis attributed to toxocariasis. ( 30273660 )
2018
28
The Use of the OMERACT Ultrasound Tenosynovitis Scoring System in Multicenter Clinical Trials. ( 29247153 )
2018
29
Inflammatory tenosynovitis and enthesitis induced by immune checkpoint inhibitor treatment. ( 29455266 )
2018
30
Idiopathic Peroneal Tenosynovitis Caused by a Previously Undiagnosed Auto-immune Condition. ( 29713574 )
2018
31
Pathological and molecular findings of avian reoviruses from clinical cases of tenosynovitis in poultry flocks from Brazil. ( 30011046 )
2018
32
Nonsurgical Treatment of De Quervain Tenosynovitis: A Prospective Randomized Trial. ( 30060681 )
2018
33
Pyogenic Flexor Tenosynovitis by Point-of-care Ultrasound in the Emergency Department. ( 30083641 )
2018
34
Flexor Tenosynovitis of the Hand Caused by Mycobacterium tuberculosis. ( 30211389 )
2018
35
Anomalous course and stenosing tenosynovitis of the extensor pollicis longus tendon at the radial styloid process: A case report. ( 30212939 )
2018
36
Treatments for de Quervain Tenosynovitis. ( 30216006 )
2018
37
Conservative management of a chronic recurrent flexor hallucis longus stenosing tenosynovitis in a pre-professional ballet dancer: a case report. ( 30305767 )
2018
38
Tenosynovitis With Psammomatous Calcifications: A Distinctive Trauma-associated Subtype of Idiopathic Calcifying Tenosynovitis With a Predilection for the Distal extremities of Middle-aged Women-A Report of 23 Cases. ( 30371510 )
2018
39
Surgical Treatment for Stenosing Peroneal Tenosynovitis. ( 30379103 )
2018
40
Current opinions regarding the management of pyogenic flexor tenosynovitis: a survey of Pulvertaft Hand Trauma Symposium attendees. ( 30387044 )
2018
41
Prevalence of a Septated First Dorsal Compartment Among Patients With and Without De Quervain Tenosynovitis: An In Vivo Anatomical Study. ( 30428712 )
2018
42
Comments on "Nonsurgical Treatment of De Quervain Tenosynovitis: A Prospective Randomized Trial". ( 30477346 )
2018
43
Tuberculous Tenosynovitis. ( 30479257 )
2018
44
Mycobacterial Tenosynovitis After Sea Urchin Spine Injury in an Immunocompromised Patient. ( 30515428 )
2018
45
The Tuck Sign-Proliferative extensor tenosynovitis of the wrist. ( 30528548 )
2018
46
Oyster-related tenosynovitis: a rare case of<i>Mycobacterium szulgai</i>in the immunocompromised. ( 29275385 )
2017
47
Polymicrobial pyogenic flexor tenosynovitis of the index finger and first ray resulting from autophagia. ( 28725123 )
2017
48
Level of agreement between three-dimensional volumetric ultrasound and real-time conventional ultrasound in the assessment of synovitis, tenosynovitis and erosions in rheumatoid arthritis patients. ( 27896420 )
2017
49
Tenosynovitis Evaluation Using Image Fusion and B-Flow - A Pilot Study on New Imaging Techniques in Rheumatoid Arthritis Patients. ( 28511227 )
2017
50
Posterior Tibial Tendon Tenosynovitis Diagnosed by Point-of-Care Ultrasound. ( 29849380 )
2017

Variations for Tenosynovitis

Expression for Tenosynovitis

Search GEO for disease gene expression data for Tenosynovitis.

Pathways for Tenosynovitis

GO Terms for Tenosynovitis

Sources for Tenosynovitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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