MCID: TNS014
MIFTS: 36

Tenosynovitis

Categories: Bone diseases, Muscle diseases

Aliases & Classifications for Tenosynovitis

MalaCards integrated aliases for Tenosynovitis:

Name: Tenosynovitis 12 45 15 17 74 64
Inflammation of Tendon Sheath 12

Classifications:



External Ids:

Disease Ontology 12 DOID:970
MeSH 45 D013717
SNOMED-CT 69 67801009
UMLS 74 C0039520

Summaries for Tenosynovitis

MalaCards based summary : Tenosynovitis, also known as inflammation of tendon sheath, is related to synovitis and bursitis. An important gene associated with Tenosynovitis is LHB (Luteinizing Hormone Beta Polypeptide). The drugs Lidocaine and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and testes.

Wikipedia : 77 Tenosynovitis is the inflammation of the fluid-filled sheath (called the synovium) that surrounds a... more...

Related Diseases for Tenosynovitis

Diseases related to Tenosynovitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 synovitis 31.7 COMP CRP
2 bursitis 30.7 CRP MRAP
3 calcific tendinitis 30.4 CRP LHB
4 arthropathy 29.9 COMP CRP
5 juvenile rheumatoid arthritis 29.7 CRP TNFRSF1B
6 reactive arthritis 29.6 COMP CRP
7 tendinitis 29.5 AKTIP COMP CRP LHB MRAP
8 psoriatic arthritis 29.4 COMP CRP TNFRSF1B
9 transient arthritis 29.1 COMP MRAP TNFRSF1B
10 vasculitis 29.0 CRP TNFRSF1B
11 bone inflammation disease 28.8 COMP CRP MRAP TNFRSF1B
12 bicipital tenosynovitis 12.5
13 nodular tenosynovitis 12.3
14 tenosynovitis of foot and ankle 12.1
15 de quervain disease 11.8
16 overuse syndrome 11.4
17 pigmented villonodular synovitis 11.4
18 gonococcal synovitis 11.3
19 repetitive motion disorders 11.1
20 repetitive stress injuries 11.1
21 cumulative trauma disorders 11.1
22 arthritis 10.8
23 rheumatoid arthritis 10.6
24 carpal tunnel syndrome 10.5
25 mononeuropathy of the median nerve, mild 10.5
26 mycobacterium marinum 10.3
27 osteomyelitis 10.2
28 salpingitis 10.2 AKTIP CRP
29 septic arthritis 10.2
30 mycobacterium kansasii 10.2
31 colobomatous microphthalmia 10.2
32 discitis 10.2 CRP MRAP
33 aortitis 10.2 CRP MRAP
34 pyuria 10.2 CRP MRAP
35 mesenteric lymphadenitis 10.1 CRP MRAP
36 systemic lupus erythematosus 10.1
37 epicondylitis 10.1
38 giant cell tumor 10.1
39 lupus erythematosus 10.1
40 renal tuberculosis 10.1 CRP MRAP
41 cartilage disease 10.1 COMP CRP
42 relapsing polychondritis 10.1 COMP CRP
43 osteoarthritis 10.1
44 frozen shoulder 10.1
45 tendinopathy 10.0
46 histoplasmosis 10.0
47 dermatitis 10.0
48 psoriasis 10.0
49 fasciitis 10.0
50 miliary tuberculosis 10.0

Graphical network of the top 20 diseases related to Tenosynovitis:



Diseases related to Tenosynovitis

Symptoms & Phenotypes for Tenosynovitis

Drugs & Therapeutics for Tenosynovitis

Drugs for Tenosynovitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 107)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 137-58-6 3676
2
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3 50-02-2 5743
3
Triamcinolone Approved, Vet_approved Phase 4,Not Applicable 124-94-7 31307
4
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3 1177-87-3
5
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
6
Racepinephrine Approved Phase 4 329-65-7 838
7
Prednisone Approved, Vet_approved Phase 4,Phase 3 53-03-2 5865
8
Methotrexate Approved Phase 4,Phase 2,Not Applicable 1959-05-2, 59-05-2 126941
9
Sulfasalazine Approved Phase 4,Not Applicable 599-79-1 5353980 5359476
10
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
11
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3 302-25-0
12
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
13
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3 2921-57-5
14
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
15
Apremilast Approved, Investigational Phase 4 608141-41-9 11561674
16
Nimodipine Approved, Investigational Phase 4 66085-59-4 4497
17
leucovorin Approved Phase 4,Phase 2 58-05-9 6006 143
18
Leflunomide Approved, Investigational Phase 4 75706-12-6 3899
19
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 59-30-3 6037
20
Prednisolone hemisuccinate Experimental Phase 4,Phase 3 2920-86-7
21 Hormones Phase 4,Phase 3
22 beta-endorphin Phase 4
23 Hormone Antagonists Phase 4,Phase 3
24 Melanocyte-Stimulating Hormones Phase 4
25 Adrenocorticotropic Hormone Phase 4
26 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
27 Diuretics, Potassium Sparing Phase 4,Not Applicable
28 Immunologic Factors Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
29 Anesthetics Phase 4,Not Applicable
30 Anesthetics, Local Phase 4,Not Applicable
31 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2
32 Anti-Arrhythmia Agents Phase 4,Not Applicable
33 Sodium Channel Blockers Phase 4,Not Applicable
34 Central Nervous System Depressants Phase 4,Not Applicable
35 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
36 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Not Applicable
37 Protective Agents Phase 4,Early Phase 1
38 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
39 glucocorticoids Phase 4,Phase 3
40 Gastrointestinal Agents Phase 4,Phase 3
41 triamcinolone acetonide Phase 4,Not Applicable
42 Respiratory System Agents Phase 4
43 Adrenergic Agents Phase 4
44 Antiemetics Phase 4,Phase 3
45 Bronchodilator Agents Phase 4
46 Epinephryl borate Phase 4
47 Adrenergic alpha-Agonists Phase 4
48 Antineoplastic Agents, Hormonal Phase 4,Phase 3
49 Triamcinolone diacetate Phase 4,Not Applicable
50 Neurotransmitter Agents Phase 4

Interventional clinical trials:

(show all 44)
# Name Status NCT ID Phase Drugs
1 Efficacy, Radiographic and Laboratory Changes in Refractory Rheumatoid Arthritis Patients Treated With H.P. Acthar Gel Unknown status NCT03082573 Phase 4 H.P. Acthar gel
2 Long Term Effectiveness of Trigger Finger Injections With Triamcinolone vs. Dexamethasone Completed NCT03641508 Phase 4 Triamcinolone;Dexamethasone
3 Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients Completed NCT01169597 Phase 4 prednisone
4 Aiming for Remission in Rheumatoid Arthritis (RA) - the ARCTIC Trial Completed NCT01205854 Phase 4
5 Ultrasound-guided Injection for DeQuervain's Recruiting NCT02038634 Phase 4 Betamethasone
6 Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone Recruiting NCT03704584 Phase 4 Treatment Group (corticosteroid injection plus lidocaine);Control Group (corticosteroid alone)
7 A Study to Evaluate the Impact of Apremilast (CC-10004) on MRI Outcomes in Subjects With Psoriatic Arthritis Recruiting NCT03783026 Phase 4 CC-10004
8 Filling Bone Erosions: a Longitudinal Multicentric HR-pQCT Study of Subcutaneous Tocilizumab in Rheumatoid Arthritis Recruiting NCT02765074 Phase 4 subcutaneous tocilizumab
9 Comparison of the Efficacy of Corticosteroid Injection and ESWT in Patients With CTS Not yet recruiting NCT03792945 Phase 4 local injection
10 Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study Terminated NCT01659242 Phase 4 Methotrexate plus sulfasalazine;Leflunomide
11 Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia Unknown status NCT02778906 Phase 3 Abatacept;Placebo
12 Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3 diclofenac sodium;Matching Placebo
13 Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders Recruiting NCT02266433 Phase 3 Ketorolac;Dexamethasone
14 Abatacept in earLy Onset Polymyalgia Rheumatica: Study ALORS Active, not recruiting NCT03632187 Phase 3 Abatacept;Placebos
15 Corticosteroid vs. Amniotic Fluid Injections in Patients With Trigger Finger Enrolling by invitation NCT03583151 Phase 3
16 Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder Terminated NCT00876317 Phase 3 Etoricoxib 60 mg;Etoricoxib 90 mg
17 Abatacept for SLE Arthritis (IM101-330) Unknown status NCT02429934 Phase 1, Phase 2 abatacept;Placebo
18 Tocilizumab Effect iN pOlymyalgia Rheumatica Completed NCT01713842 Phase 2 TCZ
19 Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care Recruiting NCT03371251 Phase 1, Phase 2 BOS161721;Placebo
20 A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate Withdrawn NCT02097264 Phase 2 NNC0109-0012;Adalimumab;placebo
21 Study Comparing One Versus Two Cortisone Injections for Trigger Finger Unknown status NCT00951236 Not Applicable One cortisone injection;Two cortisone Injections
22 Treatment of Trigger Finger With Steroid Injection Versus Steroid Injection and Splinting Unknown status NCT01886157 Not Applicable
23 Treatment of Insertional Achilles Tendinopathy by Hyaluronic Acid Injection Unknown status NCT02368561 Early Phase 1 Injection of Hyaluronic Acid -" SYNVISC" (hylan G-F 20)
24 Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients Unknown status NCT03000205 Not Applicable
25 Musculoskeletal Pathologies of the Upper Extremity in Surgical Device Mechanics Unknown status NCT03014128
26 A Clinical Trial of Splinting for DeQuervain's Tenosynovitis Completed NCT00438191
27 The Natural History of Congenital Trigger Thumbs Completed NCT01424995
28 Trigger Finger Treatment Completed NCT03847935
29 A Case Control Study to Define Clinical, Immunologic and Radiographic Features of the Aromatase Inhibitor Arthralgia Syndrome Completed NCT00890058
30 Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis Completed NCT02780999 Not Applicable
31 Study of Open and Percutaneous Release of Acquired Trigger Thumb Completed NCT03679793 Not Applicable
32 Comparison of the Clinical Examination and the Joint Ultrasonography in Lupus Patients Completed NCT02922114 Not Applicable
33 Study With Etanercept Focusing on Remission and Predictability of Remission in Real Life Clinical Practice Completed NCT02202837 etanercept;etanercept
34 Ultrasound Findings of Finger, Wrist and Knee Joints in Mucopolysaccharidosis Completed NCT02067650
35 Biomarkers of Remission in Rheumatoid Arthritis (BioRRA) Completed NCT02219347 Not Applicable DMARD cessation
36 Ultrasound-guided Intervention and Hand Tenosynovitis in Patients With Diabetes Mellitus Recruiting NCT03789526 Not Applicable
37 The Treatment of Purulent Flexor Tenosynovitis Recruiting NCT02320929 Not Applicable
38 Sinew Acupuncture for de Quervain's Tenosynovitis Recruiting NCT03472443 Not Applicable
39 Effectiveness of Astym Treatment For de Quervain's Tenosynovitis Recruiting NCT02442622 Not Applicable
40 Disparity Between Ultrasound- and Clinical Findings in Psoriatic Arthritis in Remission Recruiting NCT03396679
41 A Prospective Study Comparing Suture Anchor and Soft Tissue Pectoralis Major Tendon Techniques for Biceps Tenodesis Recruiting NCT03529162 Not Applicable
42 Prospective Study of Patients With Rheumatoid Arthritis After the Age of 65 Active, not recruiting NCT02686320
43 Prediction of Erosive Disease in Early Rheumatoid Arthritis (RA) by Ultrasound and Cartilage Biodegradation Markers Not yet recruiting NCT02464384 Not Applicable
44 Rheumatoid Arthritis Response to Methotrexate Not yet recruiting NCT03535519 Methotrexate

Search NIH Clinical Center for Tenosynovitis

Cochrane evidence based reviews: tenosynovitis

Genetic Tests for Tenosynovitis

Anatomical Context for Tenosynovitis

MalaCards organs/tissues related to Tenosynovitis:

42
Bone, Skin, Testes, Kidney, Prostate, Tonsil

Publications for Tenosynovitis

Articles related to Tenosynovitis:

(show top 50) (show all 1063)
# Title Authors Year
1
Do musculoskeletal ultrasound and magnetic resonance imaging identify synovitis and tenosynovitis at the same joints and tendons? A comparative study in early inflammatory arthritis and clinically suspect arthralgia. ( 30764862 )
2019
2
Infectious tenosynovitis of the long head of the biceps caused by methicillin-resistant Staphylococcus aureus in a patient with diabetes and small cell lung cancer. ( 30852506 )
2019
3
Functional outcome of De Quervain's tenosynovitis with longitudinal incision in surgically treated patients. ( 30600438 )
2019
4
Ultrasound-guided first dorsal compartment release for refractory de Quervain's tenosynovitis: a case report. ( 30609241 )
2019
5
Stenosing tenosynovitis : Evaluation of percutaneous release with a specially designed needle vs. open surgery. ( 30623237 )
2019
6
Important differential diagnosis in acute tenosynovitis. ( 30635314 )
2019
7
Steroid injection for stenosing tenosynovitis of the extensor carpi ulnaris. ( 30651023 )
2019
8
Investigating the optimal handle diameters and thumb orthoses for individuals with chronic de Quervain's tenosynovitis - a pilot study. ( 30689463 )
2019
9
Radiographic Soft Tissue Thickness Differentiating Pyogenic Flexor Tenosynovitis From Other Finger Infections. ( 30797654 )
2019
10
Association between Stenosing Tenosynovitis and Dupuytren's Contracture in the Hand. ( 30859045 )
2019
11
Challenging Kanavel's cardinal signs of pyogenic flexor tenosynovitis of the hand. ( 30871940 )
2019
12
Flexor Tenosynovitis Using Ultrasound. ( 30890374 )
2019
13
Endoscopic Release of Posterior Tibial Tendon Sheath for Stenosing Tenosynovitis of Posterior Tibial Tendon. ( 30899662 )
2019
14
Surgical Treatment of Tenosynovitis of Extensor Tendons of Fourth Compartment of Wrist in Nonrheumatoid Patients-A Case Series of 10 Patients in India. ( 30911211 )
2019
15
Flexor Tendon Entrapment Caused by Intratendinous Tumor-Like Chronic Proliferative Tenosynovitis. ( 30911212 )
2019
16
Cost-Effective Management of Stenosing Tenosynovitis. ( 29891265 )
2018
17
Reply to "MRI in de Quervain Tenosynovitis: Is Making the Diagnosis Sufficient?" ( 29469623 )
2018
18
MRI in De Quervain Tenosynovitis: Is Making the Diagnosis Sufficient? ( 29469625 )
2018
19
Tenosynovitis caused by Mycobacterium malmoense in two kidney transplant recipients and review of the literature. ( 29125666 )
2018
20
Nodular Tenosynovitis of the Temporomandibular Joint: An Entity Not Yet Described. ( 29762327 )
2018
21
A Rare Cause of Pyogenic Flexor Tenosynovitis: Nocardia nova. ( 29352602 )
2018
22
Lipoma arborescens-a rare cause of bilateral ankle tenosynovitis. ( 29351664 )
2018
23
Gonococcal Tenosynovitis Diagnosed with the Aid of Emergency Department Bedside Ultrasound. ( 29685466 )
2018
24
Chronic Tenosynovitis due to <i>Mycobacteria kansasii</i> in an Immunocompetent Host. ( 29850302 )
2018
25
Usefulness of ultrasound for the diagnosis of pyogenic flexor tenosynovitis: A prospective single-center study of 57 cases. ( 29396150 )
2018
26
Results of surgical treatment of De Quervain's tenosynovitis: 80 cases with a mean follow-up of 9.5 years. ( 29909297 )
2018
27
Ultrasound for the diagnosis of pyogenic flexor tenosynovitis. ( 29759904 )
2018
28
Ultrasonography for diagnosis, monitoring and treatment of tenosynovitis in patients with rheumatoid arthritis. ( 29510818 )
2018
29
Tuberculous tenosynovitis of the flexor tendons of the wrist: a case report. ( 29636100 )
2018
30
The predictive role of ultrasound-detected tenosynovitis and joint synovitis for flare in patients with rheumatoid arthritis in stable remission. Results of an Italian multicentre study of the Italian Society for Rheumatology Group for Ultrasound: the STARTER study. ( 29886430 )
2018
31
Infectious flexor hand tenosynovitis: State of knowledge. A study of 120 cases. ( 29881224 )
2018
32
'Deep Koebner' phenomenon of the flexor tendon-associated accessory pulleys as a novel factor in tenosynovitis and dactylitis in psoriatic arthritis. ( 29511028 )
2018
33
The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development. ( 29618136 )
2018
34
Tenosynovitis with Rice Body Formation Due to Mycobacterium Intracellulare Infection After Initiation of Infliximab Therapy. ( 29875354 )
2018
35
<i>Histoplasma</i> Tenosynovitis Revealed by Fungal Culture in a Patient Treated with Infliximab. ( 29419449 )
2018
36
Proximal linear extension of skin hypopigmentation after ultrasound-guided corticosteroid injection for de Quervain tenosynovitis: A Case Report. ( 29355747 )
2018
37
Kingella kingae hand and wrist tenosynovitis in young children. ( 29587602 )
2018
38
Idiopathic Peroneal Tenosynovitis Caused by a Previously Undiagnosed Auto-immune Condition. ( 29713574 )
2018
39
The Use of the OMERACT Ultrasound Tenosynovitis Scoring System in Multicenter Clinical Trials. ( 29247153 )
2018
40
Asymetric red-blue hypertrophic hand and tenosynovitis due to acrodermatitis chronica atrophicans. ( 30239931 )
2018
41
Automatic quantification of tenosynovitis on MRI of the wrist in patients with early arthritis: a feasibility study. ( 30421014 )
2018
42
Imaging detected tenosynovitis of metacarpophalangeal and wrist joints: an increasingly recognised characteristic of rheumatoid arthritis. ( 30296973 )
2018
43
Nodular skin lesion secondary to Mycobacterium abscessus tenosynovitis. ( 30016487 )
2018
44
Myelitis and tenosynovitis attributed to toxocariasis. ( 30273660 )
2018
45
Inflammatory tenosynovitis and enthesitis induced by immune checkpoint inhibitor treatment. ( 29455266 )
2018
46
Pathological and molecular findings of avian reoviruses from clinical cases of tenosynovitis in poultry flocks from Brazil. ( 30011046 )
2018
47
Nonsurgical Treatment of De Quervain Tenosynovitis: A Prospective Randomized Trial. ( 30060681 )
2018
48
Pyogenic Flexor Tenosynovitis by Point-of-care Ultrasound in the Emergency Department. ( 30083641 )
2018
49
Flexor Tenosynovitis of the Hand Caused by Mycobacterium tuberculosis. ( 30211389 )
2018
50
Anomalous course and stenosing tenosynovitis of the extensor pollicis longus tendon at the radial styloid process: A case report. ( 30212939 )
2018

Variations for Tenosynovitis

Expression for Tenosynovitis

Search GEO for disease gene expression data for Tenosynovitis.

Pathways for Tenosynovitis

GO Terms for Tenosynovitis

Sources for Tenosynovitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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