MCID: TNS014
MIFTS: 36

Tenosynovitis

Categories: Bone diseases, Muscle diseases

Aliases & Classifications for Tenosynovitis

MalaCards integrated aliases for Tenosynovitis:

Name: Tenosynovitis 12 45 15 64 17 74
Inflammation of Tendon Sheath 12

Classifications:



External Ids:

Disease Ontology 12 DOID:970
MeSH 45 D013717
SNOMED-CT 69 67801009
UMLS 74 C0039520

Summaries for Tenosynovitis

MalaCards based summary : Tenosynovitis, also known as inflammation of tendon sheath, is related to synovitis and bursitis. An important gene associated with Tenosynovitis is LHB (Luteinizing Hormone Beta Polypeptide). The drugs Epinephrine and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and kidney.

Wikipedia : 77 Tenosynovitis is the inflammation of the fluid-filled sheath (called the synovium) that surrounds a... more...

Related Diseases for Tenosynovitis

Diseases related to Tenosynovitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 synovitis 31.7 COMP CRP
2 bursitis 30.7 CRP MRAP
3 calcific tendinitis 30.5 CRP LHB
4 arthropathy 29.9 COMP CRP
5 juvenile rheumatoid arthritis 29.7 CRP TNFRSF1B
6 reactive arthritis 29.6 COMP CRP
7 tendinitis 29.5 AKTIP COMP CRP LHB MRAP
8 psoriatic arthritis 29.4 COMP CRP TNFRSF1B
9 bone inflammation disease 29.2 COMP CRP MRAP TNFRSF1B
10 transient arthritis 29.1 COMP MRAP TNFRSF1B
11 vasculitis 29.0 CRP TNFRSF1B
12 bicipital tenosynovitis 12.5
13 nodular tenosynovitis 12.3
14 tenosynovitis of foot and ankle 12.1
15 de quervain disease 11.9
16 overuse syndrome 11.4
17 pigmented villonodular synovitis 11.4
18 gonococcal synovitis 11.3
19 repetitive motion disorders 11.1
20 repetitive stress injuries 11.1
21 cumulative trauma disorders 11.1
22 arthritis 10.8
23 rheumatoid arthritis 10.6
24 carpal tunnel syndrome 10.5
25 mononeuropathy of the median nerve, mild 10.5
26 mycobacterium marinum 10.4
27 frozen shoulder 10.3
28 osteomyelitis 10.2
29 salpingitis 10.2 AKTIP CRP
30 septic arthritis 10.2
31 mycobacterium kansasii 10.2
32 discitis 10.2 CRP MRAP
33 aortitis 10.2 CRP MRAP
34 pyuria 10.2 CRP MRAP
35 mesenteric lymphadenitis 10.1 CRP MRAP
36 systemic lupus erythematosus 10.1
37 epicondylitis 10.1
38 giant cell tumor 10.1
39 lupus erythematosus 10.1
40 renal tuberculosis 10.1 CRP MRAP
41 cartilage disease 10.1 COMP CRP
42 relapsing polychondritis 10.1 COMP CRP
43 osteoarthritis 10.1
44 tendinopathy 10.0
45 systemic scleroderma 10.0
46 histoplasmosis 10.0
47 dermatitis 10.0
48 psoriasis 10.0
49 fasciitis 10.0
50 miliary tuberculosis 10.0

Graphical network of the top 20 diseases related to Tenosynovitis:



Diseases related to Tenosynovitis

Symptoms & Phenotypes for Tenosynovitis

Drugs & Therapeutics for Tenosynovitis

Drugs for Tenosynovitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 108)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4,Not Applicable 51-43-4 5816
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3 1177-87-3
3
Triamcinolone Approved, Vet_approved Phase 4,Not Applicable 124-94-7 31307
4
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 137-58-6 3676
5
Racepinephrine Approved Phase 4,Not Applicable 329-65-7 838
6
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3 50-02-2 5743
7
Prednisone Approved, Vet_approved Phase 4,Phase 3 53-03-2 5865
8
Methotrexate Approved Phase 4,Phase 2,Not Applicable 1959-05-2, 59-05-2 126941
9
Sulfasalazine Approved Phase 4,Not Applicable 599-79-1 5359476 5353980
10
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
11
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3 302-25-0
12
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
13
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3 2921-57-5
14
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
15
Apremilast Approved, Investigational Phase 4 608141-41-9 11561674
16
Nimodipine Approved, Investigational Phase 4 66085-59-4 4497
17
leucovorin Approved Phase 4,Phase 2 58-05-9 143 6006
18
Leflunomide Approved, Investigational Phase 4 75706-12-6 3899
19
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2 59-30-3 6037
20
Prednisolone hemisuccinate Experimental Phase 4,Phase 3 2920-86-7
21 Adrenocorticotropic Hormone Phase 4
22 beta-endorphin Phase 4
23 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3
24 Hormones Phase 4,Phase 3
25 Hormone Antagonists Phase 4,Phase 3
26 Melanocyte-Stimulating Hormones Phase 4
27 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Not Applicable
28 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2
29 Immunologic Factors Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
30 Protective Agents Phase 4,Early Phase 1
31 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Bronchodilator Agents Phase 4,Not Applicable
33 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
34 Adrenergic alpha-Agonists Phase 4,Not Applicable
35 Triamcinolone diacetate Phase 4,Not Applicable
36 Anti-Asthmatic Agents Phase 4,Not Applicable
37 Neurotransmitter Agents Phase 4,Not Applicable
38 Triamcinolone hexacetonide Phase 4,Not Applicable
39 Adrenergic Agonists Phase 4,Not Applicable
40 Gastrointestinal Agents Phase 4,Phase 3
41 Antiemetics Phase 4,Phase 3
42 Epinephryl borate Phase 4,Not Applicable
43 Anti-Arrhythmia Agents Phase 4,Not Applicable
44 Anesthetics Phase 4,Not Applicable
45 triamcinolone acetonide Phase 4,Not Applicable
46 Anesthetics, Local Phase 4,Not Applicable
47 Antineoplastic Agents, Hormonal Phase 4,Phase 3
48
protease inhibitors Phase 4,Phase 3
49 Respiratory System Agents Phase 4,Not Applicable
50 BB 1101 Phase 4,Phase 3

Interventional clinical trials:

(show all 46)
# Name Status NCT ID Phase Drugs
1 Efficacy, Radiographic and Laboratory Changes in Refractory Rheumatoid Arthritis Patients Treated With H.P. Acthar Gel Unknown status NCT03082573 Phase 4 H.P. Acthar gel
2 Long Term Effectiveness of Trigger Finger Injections With Triamcinolone vs. Dexamethasone Completed NCT03641508 Phase 4 Triamcinolone;Dexamethasone
3 Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients Completed NCT01169597 Phase 4 prednisone
4 Aiming for Remission in Rheumatoid Arthritis (RA) - the ARCTIC Trial Completed NCT01205854 Phase 4
5 Ultrasound-guided Injection for DeQuervain's Recruiting NCT02038634 Phase 4 Betamethasone
6 Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone Recruiting NCT03704584 Phase 4 Treatment Group (corticosteroid injection plus lidocaine);Control Group (corticosteroid alone)
7 A Study to Evaluate the Impact of Apremilast (CC-10004) on MRI Outcomes in Subjects With Psoriatic Arthritis Recruiting NCT03783026 Phase 4 CC-10004
8 Filling Bone Erosions: a Longitudinal Multicentric HR-pQCT Study of Subcutaneous Tocilizumab in Rheumatoid Arthritis Recruiting NCT02765074 Phase 4 subcutaneous tocilizumab
9 Comparison of the Efficacy of Corticosteroid Injection and ESWT in Patients With CTS Not yet recruiting NCT03792945 Phase 4 local injection
10 Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study Terminated NCT01659242 Phase 4 Methotrexate plus sulfasalazine;Leflunomide
11 Abatacept Reversing Subclinical Inflammation as Measured by MRI in ACPA Positive Arthralgia Unknown status NCT02778906 Phase 3 Abatacept;Placebo
12 Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3 diclofenac sodium;Matching Placebo
13 Abatacept in earLy Onset Polymyalgia Rheumatica: Study ALORS Recruiting NCT03632187 Phase 3 Abatacept;Placebos
14 Corticosteroid vs. Amniotic Fluid Injections in Patients With Trigger Finger Enrolling by invitation NCT03583151 Phase 3
15 Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders Terminated NCT02266433 Phase 3 Ketorolac;Dexamethasone
16 Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder Terminated NCT00876317 Phase 3 Etoricoxib 60 mg;Etoricoxib 90 mg
17 Tocilizumab Effect iN pOlymyalgia Rheumatica Completed NCT01713842 Phase 2 TCZ
18 Abatacept for SLE Arthritis (IM101-330) Recruiting NCT02429934 Phase 1, Phase 2 abatacept;Placebo
19 Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care Recruiting NCT03371251 Phase 1, Phase 2 BOS161721;Placebo
20 A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate Withdrawn NCT02097264 Phase 2 NNC0109-0012;Adalimumab;placebo
21 Study Comparing One Versus Two Cortisone Injections for Trigger Finger Unknown status NCT00951236 Not Applicable One cortisone injection;Two cortisone Injections
22 Treatment of Trigger Finger With Steroid Injection Versus Steroid Injection and Splinting Unknown status NCT01886157 Not Applicable
23 Treatment of Insertional Achilles Tendinopathy by Hyaluronic Acid Injection Unknown status NCT02368561 Early Phase 1 Injection of Hyaluronic Acid -" SYNVISC" (hylan G-F 20)
24 Anesthesia Tumescent for Surgical Management of Tenosynovitis. Completed NCT03914235 Not Applicable Lidocaine
25 A Clinical Trial of Splinting for DeQuervain's Tenosynovitis Completed NCT00438191
26 The Natural History of Congenital Trigger Thumbs Completed NCT01424995
27 Disparity Between Ultrasound- and Clinical Findings in Psoriatic Arthritis in Remission Completed NCT03396679
28 Trigger Finger Treatment Completed NCT03847935
29 A Case Control Study to Define Clinical, Immunologic and Radiographic Features of the Aromatase Inhibitor Arthralgia Syndrome Completed NCT00890058
30 Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis Completed NCT02780999 Not Applicable
31 Study of Open and Percutaneous Release of Acquired Trigger Thumb Completed NCT03679793 Not Applicable
32 Comparison of the Clinical Examination and the Joint Ultrasonography in Lupus Patients Completed NCT02922114 Not Applicable
33 Study With Etanercept Focusing on Remission and Predictability of Remission in Real Life Clinical Practice Completed NCT02202837 etanercept;etanercept
34 Ultrasound Findings of Finger, Wrist and Knee Joints in Mucopolysaccharidosis Completed NCT02067650
35 Musculoskeletal Pathologies of the Upper Extremity in Surgical Device Mechanics Completed NCT03014128
36 Biomarkers of Remission in Rheumatoid Arthritis (BioRRA) Completed NCT02219347 Not Applicable DMARD cessation
37 Ultrasound-guided Intervention and Hand Tenosynovitis in Patients With Diabetes Mellitus Recruiting NCT03789526 Not Applicable
38 The Treatment of Purulent Flexor Tenosynovitis Recruiting NCT02320929 Not Applicable
39 Sinew Acupuncture for de Quervain's Tenosynovitis Recruiting NCT03472443 Not Applicable
40 Effectiveness of Astym Treatment For de Quervain's Tenosynovitis Recruiting NCT02442622 Not Applicable
41 A Prospective Study Comparing Suture Anchor and Soft Tissue Pectoralis Major Tendon Techniques for Biceps Tenodesis Recruiting NCT03529162 Not Applicable
42 Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients Recruiting NCT03000205 Not Applicable
43 Prospective Study of Patients With Rheumatoid Arthritis After the Age of 65 Active, not recruiting NCT02686320
44 Prediction of Erosive Disease in Early Rheumatoid Arthritis (RA) by Ultrasound and Cartilage Biodegradation Markers Not yet recruiting NCT02464384 Not Applicable
45 Rheumatoid Arthritis Response to Methotrexate Not yet recruiting NCT03535519 Methotrexate
46 Musculoskeletal Ultrasound of the Ankles in Erysipelas-like Erythema of Familial Mediterranean Fever Not yet recruiting NCT03917277 Not Applicable

Search NIH Clinical Center for Tenosynovitis

Cochrane evidence based reviews: tenosynovitis

Genetic Tests for Tenosynovitis

Anatomical Context for Tenosynovitis

MalaCards organs/tissues related to Tenosynovitis:

42
Skin, Testes, Kidney, Tonsil

Publications for Tenosynovitis

Articles related to Tenosynovitis:

(show top 50) (show all 1071)
# Title Authors Year
1
Asymetric red-blue hypertrophic hand and tenosynovitis due to acrodermatitis chronica atrophicans. ( 30239931 )
2019
2
Do musculoskeletal ultrasound and magnetic resonance imaging identify synovitis and tenosynovitis at the same joints and tendons? A comparative study in early inflammatory arthritis and clinically suspect arthralgia. ( 30764862 )
2019
3
Infectious tenosynovitis of the long head of the biceps caused by methicillin-resistant Staphylococcus aureus in a patient with diabetes and small cell lung cancer. ( 30852506 )
2019
4
Myelitis and tenosynovitis attributed to toxocariasis. ( 30273660 )
2019
5
Sonographic Appearance of Flexor Carpi Radialis Tenosynovitis Associated with a Neuritis of the Palmar Cutaneous Branch of the Median Nerve. ( 31049976 )
2019
6
Androgen deprivation therapy and the risk of tenosynovitis in prostate cancer patients. ( 31111393 )
2019
7
Tenosynovitis With Psammomatous Calcifications: A Distinctive Trauma-Associated Subtype of Idiopathic Calcifying Tenosynovitis With a Predilection for the Distal extremities of Middle-Aged Women-A Report of 23 Cases. ( 30371510 )
2019
8
Surgical Treatment for Stenosing Peroneal Tenosynovitis. ( 30379103 )
2019
9
Current opinions regarding the management of pyogenic flexor tenosynovitis: a survey of Pulvertaft Hand Trauma Symposium attendees. ( 30387044 )
2019
10
The Tuck sign-proliferative extensor tenosynovitis of the wrist. ( 30528548 )
2019
11
Functional outcome of De Quervain's tenosynovitis with longitudinal incision in surgically treated patients. ( 30600438 )
2019
12
Ultrasound-guided first dorsal compartment release for refractory de Quervain's tenosynovitis: a case report. ( 30609241 )
2019
13
Stenosing tenosynovitis : Evaluation of percutaneous release with a specially designed needle vs. open surgery. ( 30623237 )
2019
14
Important differential diagnosis in acute tenosynovitis. ( 30635314 )
2019
15
Steroid injection for stenosing tenosynovitis of the extensor carpi ulnaris. ( 30651023 )
2019
16
Investigating the optimal handle diameters and thumb orthoses for individuals with chronic de Quervain's tenosynovitis - a pilot study. ( 30689463 )
2019
17
Radiographic Soft Tissue Thickness Differentiating Pyogenic Flexor Tenosynovitis From Other Finger Infections. ( 30797654 )
2019
18
Association between Stenosing Tenosynovitis and Dupuytren's Contracture in the Hand. ( 30859045 )
2019
19
Challenging Kanavel's cardinal signs of pyogenic flexor tenosynovitis of the hand. ( 30871940 )
2019
20
Flexor Tenosynovitis Using Ultrasound. ( 30890374 )
2019
21
Endoscopic Release of Posterior Tibial Tendon Sheath for Stenosing Tenosynovitis of Posterior Tibial Tendon. ( 30899662 )
2019
22
Surgical Treatment of Tenosynovitis of Extensor Tendons of Fourth Compartment of Wrist in Nonrheumatoid Patients-A Case Series of 10 Patients in India. ( 30911211 )
2019
23
Flexor Tendon Entrapment Caused by Intratendinous Tumor-Like Chronic Proliferative Tenosynovitis. ( 30911212 )
2019
24
Candida albicans tenosynovitis of the hand. ( 30927435 )
2019
25
De Quervain's Tenosynovitis. ( 30941244 )
2019
26
Dispelling the Myth of Work-Related de Quervain's Tenosynovitis. ( 30941245 )
2019
27
Difficulties making a fist in clinically suspect arthralgia: an easy applicable phenomenon predictive for RA that is related to flexor tenosynovitis. ( 31048289 )
2019
28
Sparse pustules and tenosynovitis in a young man. ( 31109850 )
2019
29
Automatic quantification of tenosynovitis on MRI of the wrist in patients with early arthritis: a feasibility study. ( 30421014 )
2018
30
Imaging detected tenosynovitis of metacarpophalangeal and wrist joints: an increasingly recognised characteristic of rheumatoid arthritis. ( 30296973 )
2018
31
Tibialis Posterior Tenosynovitis: A Unique Musculoskeletal Manifestation of Gout. ( 28632507 )
2018
32
Nodular skin lesion secondary to Mycobacterium abscessus tenosynovitis. ( 30016487 )
2018
33
Tenosynovitis caused by Mycobacterium malmoense in two kidney transplant recipients and review of the literature. ( 29125666 )
2018
34
Nodular Tenosynovitis of the Temporomandibular Joint: An Entity Not Yet Described. ( 29762327 )
2018
35
'Deep Koebner' phenomenon of the flexor tendon-associated accessory pulleys as a novel factor in tenosynovitis and dactylitis in psoriatic arthritis. ( 29511028 )
2018
36
Acute rheumatic fever associated with tenosynovitis and a unique cytokine profile. ( 30938255 )
2018
37
The predictive role of ultrasound-detected tenosynovitis and joint synovitis for flare in patients with rheumatoid arthritis in stable remission. Results of an Italian multicentre study of the Italian Society for Rheumatology Group for Ultrasound: the STARTER study. ( 29886430 )
2018
38
The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development. ( 29618136 )
2018
39
Ultrasonography for diagnosis, monitoring and treatment of tenosynovitis in patients with rheumatoid arthritis. ( 29510818 )
2018
40
Flexor tenosynovitis of the wrist including rice bodies. ( 28757343 )
2018
41
Dynamic Functional Assessment of Hand Motion Using an Animation Glove: The Effect of Stenosing Tenosynovitis. ( 28984481 )
2018
42
Rice Bodies in Tuberculous Tenosynovitis of Wrist. ( 29102590 )
2018
43
The Use of the OMERACT Ultrasound Tenosynovitis Scoring System in Multicenter Clinical Trials. ( 29247153 )
2018
44
Hallux saltans due to stenosing tenosynovitis of flexor hallucis longus: dynamic sonography and arthroscopic findings. ( 29285554 )
2018
45
Lipoma arborescens-a rare cause of bilateral ankle tenosynovitis. ( 29351664 )
2018
46
A Rare Cause of Pyogenic Flexor Tenosynovitis: Nocardia nova. ( 29352602 )
2018
47
Proximal Linear Extension of Skin Hypopigmentation After Ultrasound-Guided Corticosteroid Injection for de Quervain Tenosynovitis: A Case Presentation. ( 29355747 )
2018
48
Usefulness of ultrasound for the diagnosis of pyogenic flexor tenosynovitis: A prospective single-center study of 57 cases. ( 29396150 )
2018
49
Histoplasma Tenosynovitis Revealed by Fungal Culture in a Patient Treated with Infliximab. ( 29419449 )
2018
50
Inflammatory tenosynovitis and enthesitis induced by immune checkpoint inhibitor treatment. ( 29455266 )
2018

Variations for Tenosynovitis

Expression for Tenosynovitis

Search GEO for disease gene expression data for Tenosynovitis.

Pathways for Tenosynovitis

GO Terms for Tenosynovitis

Sources for Tenosynovitis

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10 dbSNP
11 DGIdb
17 EFO
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20 FMA
29 GO
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34 ICD10
35 ICD10 via Orphanet
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45 MeSH
46 MESH via Orphanet
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63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
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72 TGDB
73 Tocris
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75 UMLS via Orphanet
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