MCID: TNS014
MIFTS: 45

Tenosynovitis

Categories: Bone diseases, Muscle diseases

Aliases & Classifications for Tenosynovitis

MalaCards integrated aliases for Tenosynovitis:

Name: Tenosynovitis 12 44 15 62 17 70
Inflammation of Tendon Sheath 12

Classifications:



External Ids:

Disease Ontology 12 DOID:970
MeSH 44 D013717
SNOMED-CT 67 240035004
UMLS 70 C0039520

Summaries for Tenosynovitis

MalaCards based summary : Tenosynovitis, also known as inflammation of tendon sheath, is related to bicipital tenosynovitis and septic arthritis. An important gene associated with Tenosynovitis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PAK Pathway. The drugs Nimodipine and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, liver and endothelial, and related phenotype is immune system.

Wikipedia : 73 Tenosynovitis is the inflammation of the fluid-filled sheath (called the synovium) that surrounds a... more...

Related Diseases for Tenosynovitis

Diseases related to Tenosynovitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 741)
# Related Disease Score Top Affiliating Genes
1 bicipital tenosynovitis 32.7 PRTN3 CRP
2 septic arthritis 30.8 TNF MMP3 CRP
3 synovitis 30.5 TNF PRTN3 MMP3 IL6 IL1B CRP
4 gout 30.5 TNF IL6 IL1B
5 bursitis 30.4 TNF MMP3 IL6 IL1B CRP
6 skeletal tuberculosis 30.4 TNF CRP
7 miliary tuberculosis 30.3 TNF CRP CD4
8 secondary syphilis 30.3 CRP CD4
9 chikungunya 30.2 TNF IL6 IL1B
10 osteomyelitis 30.2 TNF NOD2 IL6 IL1B CRP
11 compartment syndrome 30.2 TNF IL6 CRP
12 brucellosis 30.2 TNF IL6 CRP
13 tolosa-hunt syndrome 30.2 PRTN3 CRP
14 sarcoidosis 1 30.1 TNF NOD2 IL1B CRP CD4
15 cellulitis 30.1 TNF IL6 CRP CD4
16 systemic autoimmune disease 30.1 IL6 CRP
17 systemic scleroderma 30.0 TNF IL6 CRP CD4
18 pyomyositis 30.0 CRP CD4
19 necrotizing fasciitis 30.0 IL6 IL1B CRP
20 amyloidosis 30.0 TNF IL6 IL1B CRP
21 mycobacterium tuberculosis 1 29.9 TNF NOD2 HSPD1 CD4
22 bronchiolitis obliterans 29.9 TNF IL6 CRP
23 complex regional pain syndrome 29.9 TNF IL6 IL1B
24 arthropathy 29.9 TNF MMP3 IL6 IL1B CRP
25 blau syndrome 29.9 TNF NOD2 IL1B
26 juvenile rheumatoid arthritis 29.9 TNF MMP3 IL6 IL1B CRP
27 syphilis 29.8 TNF PRTN3 IL6 CRP CD4
28 rheumatoid arthritis 29.8 TNF PRTN3 MMP3 IL6 IL1B HSPD1
29 pericarditis 29.8 TNF IL6 IL1B CRP
30 varicose veins 29.8 TNF MMP3 IL6
31 arthritis 29.8 TNF NOD2 MMP3 IL6 IL1B HSPD1
32 intracranial hypertension 29.7 TNF IL1B CCL8
33 cryptogenic organizing pneumonia 29.7 TNF PRTN3 CRP CD4
34 osteoarthritis 29.7 TNF MMP3 IL6 IL1B CRP
35 rheumatic heart disease 29.7 TNF IL6 IL1B
36 tonsillitis 29.7 TNF IL6 IL1B
37 optic neuritis 29.7 TNF IL6 IL1B
38 chickenpox 29.7 TNF IL6 CRP CD4
39 psoriatic arthritis 29.6 TNF NOD2 MMP3 IL6 IL1B CRP
40 urticaria 29.6 TNF IL6 CRP CD4
41 transient arthritis 29.6 IL6 IL1B CD4
42 pneumonia 29.6 TNF IL6 IL1B CRP
43 lymphadenitis 29.6 TNF NOD2 IL1B CRP CD4
44 endophthalmitis 29.6 TNF IL6 IL1B CRP
45 pyelonephritis 29.6 TNF IL6 IL1B CRP
46 bronchiolitis 29.6 TNF IL6 IL1B CRP
47 viral hepatitis 29.5 TNF IL6 IL1B CRP
48 vasculitis 29.5 TNF PRTN3 IL6 HSPD1 CRP
49 tendinitis 29.5 TNF SLC40A1 SH2D3A PRTN3 MMP3 IL6
50 endocarditis 29.5 TNF IL6 HSPD1 CRP

Graphical network of the top 20 diseases related to Tenosynovitis:



Diseases related to Tenosynovitis

Symptoms & Phenotypes for Tenosynovitis

MGI Mouse Phenotypes related to Tenosynovitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.32 AGBL2 CD4 CRP IL1B IL6 MMP3

Drugs & Therapeutics for Tenosynovitis

Drugs for Tenosynovitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 60)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nimodipine Approved, Investigational Phase 4 66085-59-4 4497
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
4
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
5
Racepinephrine Approved Phase 4 329-65-7 838
6
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
7
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
8
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
9
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
10
Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
11
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
12
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
13
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
14
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
15
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
16 Pharmaceutical Solutions Phase 4
17 Immunosuppressive Agents Phase 4
18 Immunologic Factors Phase 4
19 Epinephryl borate Phase 4
20 Anti-Asthmatic Agents Phase 4
21 Respiratory System Agents Phase 4
22 Betamethasone Valerate Phase 4 2152-44-5
23 Betamethasone benzoate Phase 4
24 Betamethasone sodium phosphate Phase 4
25 Betamethasone-17,21-dipropionate Phase 4
26 Ketorolac Tromethamine Phase 4
27 Anti-Arrhythmia Agents Phase 4
28 Sodium Channel Blockers Phase 4
29 Anesthetics Phase 4
30 Diuretics, Potassium Sparing Phase 4
31 Anesthetics, Local Phase 4
32 Hormone Antagonists Phase 4
33 glucocorticoids Phase 4
34 Hormones Phase 4
35 Triamcinolone diacetate Phase 4
36 triamcinolone acetonide Phase 4
37 Triamcinolone hexacetonide Phase 4
38 Gastrointestinal Agents Phase 4
39 Antineoplastic Agents, Hormonal Phase 4
40 Antiemetics Phase 4
41 Methylprednisolone Acetate Phase 4
42 Neuroprotective Agents Phase 4
43 Protective Agents Phase 4
44
Hyaluronic acid Approved, Vet_approved Phase 3 9004-61-9 53477741
45
Bupivacaine Approved, Investigational Phase 3 2180-92-9, 38396-39-3 2474
46
Diclofenac Approved, Vet_approved Phase 2, Phase 3 15307-86-5 3033
47
Etoricoxib Approved, Investigational Phase 3 202409-33-4 123619
48 Mitogens Phase 3
49 Anti-Inflammatory Agents Phase 3
50 Analgesics, Non-Narcotic Phase 3

Interventional clinical trials:

(show all 28)
# Name Status NCT ID Phase Drugs
1 Comparison of the Efficacy of Corticosteroid Injection and Extracorporeal Shock Wave Therapy (ESWT) in Patients With Carpal Tunnel Syndrome; A Prospective Randomized Controlled Trial Completed NCT03792945 Phase 4 local injection
2 Ultrasound-guided Injection for DeQuervain's Recruiting NCT02038634 Phase 4 Betamethasone
3 Differential Efficacy of Corticosteroid Solutions for Non-Operative Treatment of Digit Flexor Tenosynovitis: A Double-Blind Prospective Randomized Clinical Trial Recruiting NCT04002037 Phase 4 Triamcinolone Acetonide 40mg/mL;Triamcinolone Acetonide 10mg/mL;Dexamethasone 4 mg/ml
4 Betamethason Versus Ketorolac Injection for the Treatment of DeQuervains Tenosynovitis Active, not recruiting NCT02604537 Phase 4 betamethasone;Ketorolac
5 Corticosteroid(CS) Injections for the Treatment of Common Upper Extremity Pathologies, With or Without Lidocaine Suspended NCT03704584 Phase 4 Treatment Group (corticosteroid injection plus lidocaine);Control Group (corticosteroid alone)
6 Injection With Amniotic Fluid Versus Corticosteroid in Patients With Stenosing Tenosynovitis: a Randomized, Blinded Trial Unknown status NCT03583151 Phase 3
7 A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Diclofenac Sodium Patch for the Topical Treatment of Pain Due to Mild to Moderate Tendonitis or Bursitis Completed NCT00640939 Phase 2, Phase 3 diclofenac sodium;Matching Placebo
8 Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome; a Comparative Study Active, not recruiting NCT04434105 Phase 2, Phase 3 platlet rich plasma (PRP);Triamcinolone Acetonide;Saline
9 The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study - A Single Site, Non-inferiority Randomised Control Trial Evaluating Pain After Soft Tissue Corticosteroid Injections With and Without Local Anaesthetic Suspended NCT04253457 Phase 3 1ml of triamcinolone (40mg/1ml)
10 A Double-blinded, Prospective, Randomized, Controlled Trial Comparing Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders Terminated NCT02266433 Phase 3 Ketorolac;Dexamethasone
11 Efficacy and Safety of Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder Terminated NCT00876317 Phase 3 Etoricoxib 60 mg;Etoricoxib 90 mg
12 Musculoskeletal Ultrasound of the Ankles in Erysipelas-like Erythema of Familial Mediterranean Fever Unknown status NCT03917277
13 Sinew Acupuncture for de Quervain's Tenosynovitis: a Randomised Controlled Trial Unknown status NCT03472443
14 A Prospective, Randomized Study Comparing One vs. Two Cortisone Injections for Trigger Finger Unknown status NCT00951236 One cortisone injection;Two cortisone Injections
15 Treatment of Trigger Finger With Steroid Injection Versus Steroid Injection and Splinting: A Randomized Controlled Trial Unknown status NCT01886157
16 Efficacy of Tumescent Local Anesthesia in the Surgical Management of Tenosynovitis. Completed NCT03914235 Lidocaine
17 Effectiveness of Astym Treatment For de Quervain's Tenosynovitis Completed NCT02442622
18 A Clinical Trial of Full Time vs. As Needed Splint Wear for DeQuervain's Tenosynovitis Completed NCT00438191
19 Ultrasound-guided Intervention and Hand Tenosynovitis in Patients With Diabetes Mellitus Completed NCT03789526
20 Effectiveness of Neural Therapy in Patients With De Quervain Tenosynovitis Completed NCT04384536
21 TENS and Kinesio Tape for Treatment Lateral Epicondylitis Completed NCT03968796
22 Trigger Finger Treatment - An Outcomes Study. Comparing 6 Traditional Treatment Techniques Completed NCT03847935
23 The Natural History of Congenital Trigger Thumbs Completed NCT01424995
24 The Treatment of Purulent Flexor Tenosynovitis - Is Postoperative Catheter Irrigation Necessary? A Prospective Randomized Trial. Recruiting NCT02320929
25 Resection of One or Both Slips of the Flexor Digitorum Superficialis Tendon for Cases of Severe Trigger Fingers. A Randomized Prospective Single Center Study Recruiting NCT04675892
26 Treating Depression in Patients With De Quervain's Tenosynovitis; An Integrated Web Based Skills Intervention Active, not recruiting NCT04069741
27 Dry Needling and Heavy Slow Load Exercise Versus Traditional Physical Therapy in the Treatment of Individuals With Bicipital Tendinopathy; A Pilot Study Not yet recruiting NCT04073212
28 A Prospective Randomized Study Comparing Suture Anchor and Soft Tissue Pectoralis Major Tendon Techniques for Biceps Tenodesis Terminated NCT03529162

Search NIH Clinical Center for Tenosynovitis

Cochrane evidence based reviews: tenosynovitis

Genetic Tests for Tenosynovitis

Anatomical Context for Tenosynovitis

MalaCards organs/tissues related to Tenosynovitis:

40
Bone Marrow, Liver, Endothelial, Bone, Prostate, Colon, Salivary Gland

Publications for Tenosynovitis

Articles related to Tenosynovitis:

(show top 50) (show all 3220)
# Title Authors PMID Year
1
Spontaneous extensor tendon rupture due to scaphoid osteophyte: A case report and literature review. 61
33786359 2021
2
Outcome of percutaneous trigger finger release technique using a 20-gauge hypodermic needle. 61
33717917 2021
3
Ultrasound to identify SLE patients with musculoskeletal symptoms who respond best to therapy: The USEFUL longitudinal multicentre study. 61
33792659 2021
4
A Comparison of Pronator Quadratus Preservation and Dissection Approaches for Volar Plating of Comminuted Intra-articular Distal Radius Fracture. 61
33559995 2021
5
Tennis overuse injuries in the upper extremity. 61
33009583 2021
6
Sea urchin injuries: a review and clinical approach algorithm. 61
31259638 2021
7
Assessment of short-term response and review of technique of ultrasound-guided percutaneous A1 pulley release for the treatment of trigger finger. 61
33749135 2021
8
Superb Microvascular Imaging in Assessment of Synovitis and Tenosynovitis in Juvenile Idiopathic Arthritis. 61
33661799 2021
9
Pyogenic Extensor Tenosynovitis of the Wrist-A Cause of Spontaneous Extensor Tendon Rupture: A Report of 2 Cases. 61
33657059 2021
10
Development of a Murine Model of Pyogenic Flexor Tenosynovitis. 61
33411464 2021
11
Paraffin bath therapy in De Quervain's tenosynovitis: a single-blind randomized controlled trial. 61
33675398 2021
12
CORR Insights®: Are Patient Expectations and Illness Perception Associated with Patient-reported Outcomes from Surgical Decompression in de Quervain's Tenosynovitis? 61
33704096 2021
13
Ultrasound, magnetic resonance imaging and radiography of the finger joints in psoriatic arthritis patients. 61
33734348 2021
14
Which ultrasound lesions contribute to dactylitis in psoriatic arthritis and their reliability in a clinical setting. 61
33155158 2021
15
Differentiating rheumatoid and psoriatic arthritis: a systematic analysis of high-resolution magnetic resonance imaging features-preliminary findings. 61
32845377 2021
16
Gender-Related Differences in Disease Activity and Clinical Features in Patients with Peripheral Psoriatic Arthritis: A Multi-Center Study. 61
33771757 2021
17
The Role of Ultrasound in Research and Clinical Practice in Psoriatic Arthritis: Highlights From the GRAPPA Ultrasound Workshop. 61
33649071 2021
18
High-resolution ultrasonography in carpal tunnel syndrome: role of ancillary criteria in diagnosis and response to steroid injection. 61
32696280 2021
19
Ultrasound assessment of carpal tunnel in rheumatoid arthritis and idiopathic carpal tunnel syndrome. 61
32696282 2021
20
Polymicrobial Extensor Tenosynovitis Including Mycobacterium chelonae Caused by a Dog Bite: A Case Report. 61
33543870 2021
21
Problematic smartphone use is associated with de Quervain's tenosynovitis symptomatology among young adults. 61
33667881 2021
22
Emerging new avian reovirus variants from cases of enteric disorders and arthritis/tenosynovitis in Brazilian poultry flocks. 61
33448227 2021
23
Histoplasmosis tenosynovitis of the forearm and wrist: imaging, surgical and pathologic findings. 61
33537878 2021
24
Prosthetic Joint Infections Due to Histoplasma capsulatum: A Report of 3 Cases. 61
33718797 2021
25
Are Plain X-Rays Necessary in the Diagnosis of De Quervain's Tenosynovitis? 61
33552695 2021
26
Ultrasound diagnosis of pyogenic flexor tenosynovitis in a 9-month-old infant: a rare case report. 61
33547565 2021
27
Isolated multidrug-resistant tubercular tenosynovitis of the flexor tendon of the little finger. 61
33608337 2021
28
Contribution of Ultrasonography of hands and wrists in Early Rheumatoid Arthritis. 61
33605862 2021
29
Value of MRI and ultrasound for prediction of therapeutic response and erosive progression in patients with early rheumatoid arthritis managed by an aggressive treat-to-target strategy. 61
33547228 2021
30
Musculoskeletal ultrasound using superb microvascular imaging documents treatment response to biosimilar infliximab in rheumatoid arthritis. 61
33602763 2021
31
Prominent tenosynovitis on ultrasonography: A useful sign for the diagnosis of Blau syndrome. 61
33687830 2021
32
Tenosynovitis has a high sensitivity for early ACPA-positive and ACPA-negative RA: a large cross-sectional MRI study. 61
33547063 2021
33
A histological study on the tendons at chiasma plantare in pes cavus. 61
33129658 2021
34
Lateral Heel Pain Caused by Impingement of Hypertrophic Peroneal Tubercle and Os Peroneum. 61
33505747 2021
35
CT scan assessment of the dimensions and morphological variations of the peroneal tubercle. 61
32057621 2021
36
Bicipital synovial cyst as the sole musculoskeletal presentation of systemic juvenile idiopathic arthritis-case report. 61
33430713 2021
37
Ultrasound findings of plantar plate tears of the lesser metatarsophalangeal joints. 61
33423073 2021
38
Ultrasonographic features of arthritis in patients with primary Sjögren's syndrome and its clinical significance. 61
33431179 2021
39
Ultrasound-Guided Biceps Tendon Sheath Injections Frequently Extravasate Into the Glenohumeral Joint. 61
33453348 2021
40
Extensor Tenosynovitis due to Mycobacterium marseillense Infection in a Renal Transplant Recipient. 61
33448712 2021
41
Diabetes: a silent player in musculoskeletal interventional radiology response. 61
33532654 2021
42
Musculoskeletal Pain Symptoms and Injuries Among Endoscopists Who Perform ERCP. 61
32144599 2021
43
The new role of musculoskeletal ultrasound in the treat-to-target management of juvenile idiopathic arthritis. 61
33493330 2021
44
Disseminated Mycobacterium haemophilum With Tenosynovitis in a Liver Transplant Recipient. 61
31880608 2021
45
Subluxation of the extensor carpi ulnaris on magnetic resonance imaging on neutral wrist position: correlation with tenosynovitis of the extensor carpi ulnaris and translation of the distal radioulnar joint. 61
33432435 2021
46
Tuberculosis tenosynovitis: A rare case report. 61
33681922 2021
47
Synovitis and Tenosynovitis on Ultrasound as Predictors of DMARD Tapering Failure in Patients with Long-Standing Rheumatoid Arthritis in Clinical Remission or Low Disease Activity. 61
33492685 2021
48
Predictors of joint damage progression and stringent remission in patients with established rheumatoid arthritis in clinical remission. 61
32929463 2021
49
Imbalanced MMP-3 and MMP-12 serum levels in systemic lupus erythematosus patients with Jaccoud's arthropathy and a distinctive MRI pattern. 61
33404658 2021
50
Preexisting autoimmune disease and immune-related adverse events associated with anti-PD-1 cancer immunotherapy: a national case series from the Canadian Research Group of Rheumatology in Immuno-Oncology. 61
33471137 2021

Variations for Tenosynovitis

Expression for Tenosynovitis

Search GEO for disease gene expression data for Tenosynovitis.

Pathways for Tenosynovitis

Pathways related to Tenosynovitis according to GeneCards Suite gene sharing:

(show all 36)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.27 TNF PRTN3 NOD2 MMP3 IL6 IL1B
2
Show member pathways
13.21 TNF IL6 IL1B CD4 CCL8 CCL7
3
Show member pathways
12.78 TNF IL6 IL1B HSPD1 CD4
4
Show member pathways
12.5 TNF NOD2 IL6 IL1B CD4
5
Show member pathways
12.27 TNF IL6 CCL8 CCL7
6
Show member pathways
12.26 TNF IL6 IL1B CRP
7 12.17 TNF NOD2 IL6 IL1B
8
Show member pathways
12.17 TNF MMP3 IL6 IL1B CCL7
9 12.09 TNF IL6 IL1B HSPD1
10 11.99 TNF IL6 IL1B CD4
11 11.97 TNF NOD2 IL6 IL1B HSPD1
12 11.87 TNF MMP3 IL6 IL1B
13 11.85 TNF IL6 IL1B
14 11.84 TNF IL6 IL1B
15
Show member pathways
11.79 IL6 IL1B CD4
16 11.79 TNF IL6 IL1B CD4
17 11.75 TNF MMP3 IL6 IL1B
18 11.73 TNF IL1B CD4
19 11.7 TNF IL6 IL1B
20 11.6 TNF IL6 IL1B
21
Show member pathways
11.59 TNF IL6 IL1B CD4
22 11.54 TNF IL6 IL1B CD4
23 11.48 TNF IL6 IL1B
24 11.46 TNF IL6 IL1B
25 11.42 TNF IL6 IL1B
26 11.4 TNF NOD2 MMP3 IL6 IL1B
27
Show member pathways
11.36 TNF MMP3 IL6 IL1B
28 11.32 TNF IL6 IL1B
29 11.28 TNF IL6 IL1B
30 11.22 TNF IL6 IL1B
31 11.21 TNF IL6 IL1B HSPD1
32 11.19 TNF IL6 IL1B
33 10.95 TNF IL6 IL1B CCL8 CCL7
34 10.91 TNF IL6 CRP
35 10.74 IL6 IL1B
36 10.39 TNF IL6 IL1B CD4

GO Terms for Tenosynovitis

Cellular components related to Tenosynovitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 TNF PRTN3 PRSS57 MMP3 IL6 IL1B
2 membrane raft GO:0045121 9.46 TNF PRTN3 HSPD1 CD4
3 extracellular space GO:0005615 9.32 TNF PRTN3 PRSS57 MMP3 IL6 IL1B

Biological processes related to Tenosynovitis according to GeneCards Suite gene sharing:

(show all 39)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.95 TNF IL6 IL1B CD4 CCL8 CCL7
2 cellular response to lipopolysaccharide GO:0071222 9.88 TNF NOD2 IL6 IL1B
3 inflammatory response GO:0006954 9.88 TNF IL6 IL1B CRP CCL8 CCL7
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.86 TNF NOD2 IL6 IL1B
5 positive regulation of inflammatory response GO:0050729 9.85 TNF IL1B HSPD1
6 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.85 NOD2 IL6 CD4
7 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.84 TNF SH2D3A IL6
8 positive regulation of JNK cascade GO:0046330 9.83 TNF NOD2 IL1B
9 regulation of insulin secretion GO:0050796 9.83 TNF IL6 IL1B
10 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.83 TNF NOD2 CD4 CCL8 CCL7
11 cellular response to organic cyclic compound GO:0071407 9.82 TNF NOD2 IL1B
12 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.81 TNF NOD2 IL1B
13 response to glucocorticoid GO:0051384 9.81 TNF IL6 HSPD1
14 positive regulation of interferon-gamma production GO:0032729 9.8 TNF IL1B HSPD1
15 positive regulation of T cell proliferation GO:0042102 9.8 IL6 IL1B CD4
16 defense response to Gram-positive bacterium GO:0050830 9.8 TNF NOD2 IL6 CRP
17 positive regulation of interleukin-1 beta production GO:0032731 9.79 TNF NOD2 IL6
18 JNK cascade GO:0007254 9.78 TNF SH2D3A NOD2
19 positive regulation of phagocytosis GO:0050766 9.77 TNF NOD2 IL1B
20 monocyte chemotaxis GO:0002548 9.74 IL6 CCL8 CCL7
21 positive regulation of interleukin-10 production GO:0032733 9.72 NOD2 IL6 HSPD1
22 negative regulation of neurogenesis GO:0050768 9.7 TNF IL6 IL1B
23 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.69 TNF NOD2 IL6
24 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.68 TNF IL6
25 positive regulation of monocyte chemotactic protein-1 production GO:0071639 9.68 NOD2 IL1B
26 regulation of neuroinflammatory response GO:0150077 9.66 MMP3 IL6
27 regulation of establishment of endothelial barrier GO:1903140 9.65 TNF IL1B
28 response to peptidoglycan GO:0032494 9.65 NOD2 IL6
29 positive regulation of glial cell proliferation GO:0060252 9.63 TNF IL6 IL1B
30 cytokine-mediated signaling pathway GO:0019221 9.63 TNF PRTN3 MMP3 IL6 IL1B CD4
31 positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 9.62 TNF NOD2
32 positive regulation of interleukin-8 production GO:0032757 9.62 TNF NOD2 IL6 IL1B
33 positive regulation of fever generation GO:0031622 9.6 TNF IL1B
34 sequestering of triglyceride GO:0030730 9.58 TNF IL1B
35 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.54 TNF IL1B
36 positive regulation of neuroinflammatory response GO:0150078 9.54 TNF IL6 IL1B
37 negative regulation of lipid storage GO:0010888 9.43 TNF IL6 CRP
38 vascular endothelial growth factor production GO:0010573 9.13 TNF IL6 IL1B
39 positive regulation of interleukin-6 production GO:0032755 9.02 TNF NOD2 IL6 IL1B HSPD1

Molecular functions related to Tenosynovitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 TNF IL6 IL1B CCL8 CCL7

Sources for Tenosynovitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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