Aliases & Classifications for Teratoma, Ovarian

MalaCards integrated aliases for Teratoma, Ovarian:

Name: Teratoma, Ovarian 57
Dermoid Cyst, Ovarian 57
Ovarian Teratoma 17

Characteristics:

OMIM®:

57 (Updated 05-Apr-2021)
Inheritance:
autosomal dominant


HPO:

31
teratoma, ovarian:
Inheritance autosomal dominant inheritance


External Ids:

OMIM® 57 166950
MedGen 41 C0280131
SNOMED-CT via HPO 68 263681008 716077006

Summaries for Teratoma, Ovarian

MalaCards based summary : Teratoma, Ovarian, also known as dermoid cyst, ovarian, is related to ovarian germ cell teratoma and dermoid cyst of ovary. The drugs Etoposide and Levoleucovorin have been mentioned in the context of this disorder. Affiliated tissues include ovary, thyroid and bone, and related phenotype is ovarian teratoma.

More information from OMIM: 166950

Related Diseases for Teratoma, Ovarian

Diseases related to Teratoma, Ovarian via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 200)
# Related Disease Score Top Affiliating Genes
1 ovarian germ cell teratoma 11.4
2 dermoid cyst of ovary 11.1
3 encephalitis 10.8
4 mature teratoma 10.6
5 gliomatosis peritonei 10.5
6 benign teratoma 10.4
7 limbic encephalitis 10.4
8 autoimmune encephalitis 10.4
9 thyroid carcinoma 10.4
10 struma ovarii 10.4
11 paraneoplastic limbic encephalitis 10.4
12 ovarian cyst 10.3
13 peritonitis 10.3
14 germ cells tumors 10.3
15 thyroid cancer, nonmedullary, 1 10.2
16 ataxia and polyneuropathy, adult-onset 10.2
17 endometriosis 10.2
18 neuroblastoma 10.2
19 malignant teratoma 10.2
20 adenoma 10.2
21 carcinoid syndrome 10.2
22 myoclonus 10.2
23 paraneoplastic syndromes 10.2
24 squamous cell carcinoma 10.1
25 adenocarcinoma 10.1
26 intestinal obstruction 10.1
27 opsoclonus-myoclonus syndrome 10.1
28 encephalopathy 10.1
29 rare tumor 10.1
30 ovarian cancer 10.1
31 ovarian germ cell cancer 10.1
32 respiratory failure 10.1
33 melanoma 10.1
34 mucinous adenocarcinoma 10.1
35 cystadenocarcinoma 10.1
36 oligodendroglioma 10.1
37 appendix adenocarcinoma 10.1
38 hemolytic anemia 10.1
39 mature teratoma of the ovary 10.1
40 appendicitis 10.1
41 teratoma with malignant transformation 10.1
42 glioma susceptibility 1 10.0
43 medulloblastoma 10.0
44 retinoblastoma 10.0
45 wilms tumor 1 10.0
46 anemia, autoimmune hemolytic 10.0
47 hydatidiform mole, recurrent, 1 10.0
48 ocular motor apraxia 10.0
49 osteogenic sarcoma 10.0
50 deficiency anemia 10.0

Graphical network of the top 20 diseases related to Teratoma, Ovarian:



Diseases related to Teratoma, Ovarian

Symptoms & Phenotypes for Teratoma, Ovarian

Human phenotypes related to Teratoma, Ovarian:

31
# Description HPO Frequency HPO Source Accession
1 ovarian teratoma 31 HP:0012226

Symptoms via clinical synopsis from OMIM®:

57 (Updated 05-Apr-2021)
G U:
ovarian teratoma

Clinical features from OMIM®:

166950 (Updated 05-Apr-2021)

Drugs & Therapeutics for Teratoma, Ovarian

Drugs for Teratoma, Ovarian (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etoposide Approved Phase 2 33419-42-0 36462
2
Levoleucovorin Approved, Investigational Phase 2 68538-85-2 149436
3
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
4
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
5
Dactinomycin Approved, Investigational Phase 2 50-76-0 2019 457193
6
leucovorin Approved Phase 2 58-05-9 6006
7
Doxorubicin Approved, Investigational Phase 2 23214-92-8 31703
8
Lenograstim Approved, Investigational Phase 2 135968-09-1
9
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
10
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
11
Folic acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
12 Vitamin B9 Phase 2
13 Antibiotics, Antitubercular Phase 2
14 Trace Elements Phase 2
15 Nutrients Phase 2
16 Immunosuppressive Agents Phase 2
17 Micronutrients Phase 2
18
Liposomal doxorubicin Phase 2 31703
19 Alkylating Agents Phase 2
20 Immunologic Factors Phase 2
21 Folate Phase 2
22 Anti-Infective Agents Phase 2
23 Antirheumatic Agents Phase 2
24 Vitamin B Complex Phase 2
25 Folic Acid Antagonists Phase 2
26 Etoposide phosphate Phase 2
27 Vitamins Phase 2
28 Anti-Bacterial Agents Phase 2
29 Dermatologic Agents Phase 2
30 Antidotes Phase 2
31 Antimetabolites Phase 2
32 Calcium, Dietary Phase 2
33 Protective Agents Phase 2
34
Calcium Nutraceutical Phase 2 7440-70-2 271

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 PROTOCOL FOR THE TREATMENT OF MALIGNANT NON-TESTICULAR GERM CELL TUMORS Completed NCT00002489 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;etoposide;leucovorin calcium;methotrexate;vincristine sulfate
2 A PHASE II STUDY OF CELLULAR ADOPTIVE IMMUNOTHERAPY AS PROPHYLAXIS FOR CYTOMEGALOVIRUS DISEASE AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION Completed NCT00002673 Phase 2
3 Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Study of Nab-Paclitaxel (Nanoparticle Albumin Bound-Paclitaxel) in Patients With Advanced Solid Tumors Withdrawn NCT00499291 paclitaxel albumin-stabilized nanoparticle formulation

Search NIH Clinical Center for Teratoma, Ovarian

Genetic Tests for Teratoma, Ovarian

Anatomical Context for Teratoma, Ovarian

MalaCards organs/tissues related to Teratoma, Ovarian:

40
Ovary, Thyroid, Bone, Bone Marrow, Brain, Liver, Lung

Publications for Teratoma, Ovarian

Articles related to Teratoma, Ovarian:

(show top 50) (show all 1076)
# Title Authors PMID Year
1
Familial occurrence of mature ovarian teratomas. 57
4022488 1985
2
The origin of ovarian teratomas. 57
6363699 1984
3
Ovarian teratomas and genetics of germ-cell formation. 57
63792 1976
4
Parthenogenic origin of benign ovarian teratomas. 57
162806 1975
5
The development of teratomas from parthenogenetically activated ovarian mouse eggs. 57
4826282 1974
6
Familial incidence of ovarian dermoid cysts. 57
4707237 1973
7
Mucinous Cystic Adenoma of the Liver: A Thought-Provoking Case of an Uncommon Hepatic Neoplasm. 61
33811210 2021
8
Distinctive pattern of left-right asymmetry of ovarian benign teratomas in Chinese population: a 12-year-long cross-sectional study. 61
33427916 2021
9
Syringic acid regulates suppression of the STAT3/JNK/AKT pathway via inhibition of human ovarian teratoma cancer cell (PA-1) growth-in vitro study. 61
33759321 2021
10
Ovarian teratoma masquerading as encephalitis in an adolescent. 61
33773057 2021
11
Struma ovarii in bilateral ovarian teratoma-case report and literature review. 61
33732424 2021
12
Methylation profiles of imprinted genes are distinct between mature ovarian teratoma, complete hydatidiform mole, and extragonadal mature teratoma. 61
32873866 2021
13
[Anti-N-methyl-D-aspartate receptor encephalitis and ovarian teratoma]. 61
32659454 2021
14
VNS Stopping Anti-NMDA Receptor Encephalitis-Triggered Nonconvulsive Status Epilepticus. 61
33091646 2021
15
DDB2 regulates DNA replication through PCNA-independent degradation of CDT2. 61
33557942 2021
16
Ovarian Sparing Surgery in Mature Ovarian Teratomas in Children: A 20-Year Single-Center Experience. 61
32950035 2021
17
Cycloid psychosis as a psychiatric expression of anti-NMDAR encephalitis. A systematic review of case reports accomplished with the authors' cooperation. 61
33270360 2021
18
Leucine Zipper 4 Autoantibody: A Novel Germ Cell Tumor and Paraneoplastic Biomarker. 61
33583072 2021
19
Malignant struma ovarii: next-generation sequencing of six cases revealed Nras, Braf, and Jak3 mutations. 61
32743766 2021
20
Anti-N-Methyl-D-Aspartate Receptor Encephalitis with Decrease in Blood Flow in Cerebellum. 61
33613239 2021
21
LINC00324 facilitates cell proliferation through competing for miR‑214‑5p in immature ovarian teratocarcinoma. 61
33416104 2021
22
Distinct cerebral 18F-FDG PET metabolic patterns in anti-N-methyl-D-aspartate receptor encephalitis patients with different trigger factors. 61
33717212 2021
23
Clinical Characteristics and Outcome of Neuronal Surface Antibody-Mediated Autoimmune Encephalitis Patients in a National Cohort. 61
33767656 2021
24
Ovarian teratoma with pituitary tissue: A case report. 61
33364180 2021
25
Anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma in Korea. 61
33498105 2021
26
Mature ovarian teratoma associated with anti-N-Methyl-D-aspartate receptor encephalitis: A case report. 61
33510121 2021
27
Cecal dermoid masquerading dermoid cyst of ovary: a case report and review of the literature. 61
33514417 2021
28
Clinical analysis of five case reports of ovarian teratoma with anti-N-methyl-D-aspartate receptor encephalitis. 61
33440951 2021
29
Occult Growing Teratoma as the Cause of Protracted Symptoms in a Patient with Anti-NMDA-Receptor Encephalitis and Prior Ovarian Teratoma Removal: Implications for Continued Monitoring and Treatment. 61
33480209 2021
30
Homemade Glove Retrieval Bag in Laparoscopic Complete Excision of Benign Ovarian Teratoma with Ovarian Tissue Preservation in Children: A Case Series. 61
32781234 2020
31
Follicular carcinoma arising from struma ovarii. A case report. 61
33393527 2020
32
Single nucleotide polymorphism array and cytogenetic analyses of ovarian teratomas in children. 61
33377559 2020
33
Multiple ectopic goiter in the retroperitoneum, abdominal wall, liver, and diaphragm: A case report and review of literature. 61
33344620 2020
34
Struma ovarii: two case reports of a rare teratoma of the ovary. 61
33343869 2020
35
Paraneoplastic anti-NMDA receptor encephalitis in 1830? 61
32978290 2020
36
A mature cystic teratoma adherent to the vaginal wall: a case report. 61
33233994 2020
37
Ovarian teratoma-associated anti-NMDAR encephalitis: a single-institute series of six patients from China. 61
33216164 2020
38
HLA-A and HLA-DRB1 may play a unique role in ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis. 61
33160385 2020
39
Coexistence of endometriosis in women with mature cystic ovarian teratoma may not be rare. 61
32413526 2020
40
Ovarian teratoma-associated anti-NMDAR encephalitis in a 12-year-old girl. 61
33219185 2020
41
Ovarian teratoma in a woodchuck (Marmota monax) with hepatocellular carcinoma: radiologic and pathologic features. 61
33228678 2020
42
A refractory anti-NMDA receptor encephalitis successfully treated by bilateral salpingo-oophorectomy and intrathecal injection of methotrexate and dexamethasone: a case report. 61
33100078 2020
43
Expression of SMAD4 is Retained in Most Gynecologic Tumors with Mucinous Differentiation. 61
31569186 2020
44
Oily Ascites Revealing a Spontaneous Rupture of a Mature Ovarian Cystic Teratoma. 61
32964191 2020
45
Anti-NMDA receptor encephalitis with neurologic sequelae refractory to conservative therapy with complete response to adjuvant therapy. 61
32596435 2020
46
Commentary on "Psychosis associated to CASPR2 autoantibodies and ovarian teratoma: A case report". 61
32505929 2020
47
Opsoclonus-ataxia syndrome and mature ovarian teratoma in an adolescent. 61
32637527 2020
48
Anti-NMDA receptor encephalitis associated with ovarian tumor: the gynecologist point of view. 61
32556515 2020
49
Squamous Cell Carcinoma from Abscessed, Mature Cystic Ovarian Teratoma - A Case Report and Literature Review. 61
32606195 2020
50
Single-cell transcriptional profiling identifies a cluster of potential metastasis-associated UBE2C+ cells in immature ovarian teratoma. 61
32505346 2020

Variations for Teratoma, Ovarian

Expression for Teratoma, Ovarian

Search GEO for disease gene expression data for Teratoma, Ovarian.

Pathways for Teratoma, Ovarian

GO Terms for Teratoma, Ovarian

Sources for Teratoma, Ovarian

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....