MCID: TST026
MIFTS: 40

Testicular Germ Cell Cancer

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Testicular Germ Cell Cancer

MalaCards integrated aliases for Testicular Germ Cell Cancer:

Name: Testicular Germ Cell Cancer 12 15
Testicular Germ Cell Tumor 44 73
Testicular Malignant Germ Cell Tumor 73
Testicular Germ Cell Neoplasm 12
Germ Cell Tumor of Testis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5557
MeSH 44 C563236
NCIt 50 C8591

Summaries for Testicular Germ Cell Cancer

Disease Ontology : 12 A testicular cancer that has material basis in germ cells.

MalaCards based summary : Testicular Germ Cell Cancer, also known as testicular germ cell tumor, is related to testicular germ cell tumor and germ cell cancer. An important gene associated with Testicular Germ Cell Cancer is MEG3 (Maternally Expressed 3). The drugs Cisplatin and Imiquimod have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and testis.

Related Diseases for Testicular Germ Cell Cancer

Diseases in the Testicular Germ Cell Cancer family:

Testicular Malignant Germ Cell Cancer

Diseases related to Testicular Germ Cell Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 95)
# Related Disease Score Top Affiliating Genes
1 testicular germ cell tumor 34.3 ALPP DMRT1 KITLG
2 germ cell cancer 31.1 ALPP AR DMRT1 ESR2 KITLG
3 seminoma 29.8 ALPP ESR2
4 testicular cancer 29.7 ALPP AR XIST
5 prostate cancer 29.0 AR ESR2 MEG3 SPRY4-IT1 XIST
6 testicular germ cell tumor 1 12.6
7 pediatric testicular germ cell tumor 12.5
8 testicular germ cell tumor non-seminomatous 12.3
9 testicular malignant germ cell cancer 11.4
10 pigmented villonodular synovitis 11.3
11 testicular seminoma 11.3
12 germ cells tumors 11.1
13 testicular microlithiasis 10.4
14 embryonal carcinoma 10.4
15 teratoma 10.3
16 rhabdomyosarcoma 10.2
17 choriocarcinoma 10.2
18 nonseminomatous germ cell tumor 10.2
19 in situ carcinoma 10.2
20 postmenopausal atrophic vaginitis 10.2 AR ESR2
21 vaginitis 10.2 AR ESR2
22 transsexualism 10.2 AR ESR2
23 gender identity disorder 10.2 AR ESR2
24 prostatic hyperplasia, benign 10.1 AR ESR2
25 mixed germ cell tumor 10.1
26 oligospermia 10.1 AR KITLG
27 prostatic hypertrophy 10.1 ALPP AR
28 stroke, ischemic 10.1
29 dermatomyositis 10.1
30 down syndrome 10.1
31 wilms tumor 1 10.1
32 wilms tumor 6 10.1
33 angiosarcoma 10.1
34 azoospermia 10.1
35 endodermal sinus tumor 10.1
36 trophoblastic neoplasm 10.1
37 mature teratoma 10.1
38 hydrocele 10.1
39 male reproductive organ cancer 10.1 AR ESR2
40 serous cystadenocarcinoma 10.0 ALPP ESR2
41 gonadoblastoma 10.0 ALPP RBMY1A1
42 male reproductive system disease 10.0 AR ESR2
43 von hippel-lindau syndrome 10.0
44 neuroblastoma 10.0
45 intussusception 10.0
46 cryptorchidism, unilateral or bilateral 10.0
47 body mass index quantitative trait locus 1 10.0
48 bone mineral density quantitative trait locus 3 10.0
49 thrombocytopenia 10.0
50 ulcerative colitis 10.0

Graphical network of the top 20 diseases related to Testicular Germ Cell Cancer:



Diseases related to Testicular Germ Cell Cancer

Symptoms & Phenotypes for Testicular Germ Cell Cancer

Drugs & Therapeutics for Testicular Germ Cell Cancer

Drugs for Testicular Germ Cell Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 312)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
2
Imiquimod Approved, Investigational Phase 4 99011-02-6 57469
3
Testosterone enanthate Approved Phase 4,Phase 2,Phase 3 315-37-7 9416
4
Methyltestosterone Approved Phase 4,Phase 2,Phase 3 58-18-4 6010
5
Testosterone undecanoate Approved, Investigational Phase 4,Phase 2,Phase 3 5949-44-0
6
Testosterone Approved, Investigational Phase 4,Phase 2,Phase 3 58-22-0 6013
7
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
8 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3 979-32-8
9
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
10 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
11 interferons Phase 4,Phase 1,Phase 2
12 Adjuvants, Immunologic Phase 4,Phase 3,Phase 1,Phase 2
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
14 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Not Applicable
15 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
16 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
17 Interferon Inducers Phase 4,Phase 1,Phase 2
18 Androgens Phase 4,Phase 2,Phase 3
19 Testosterone 17 beta-cypionate Phase 4,Phase 2,Phase 3
20 Anabolic Agents Phase 4,Phase 2,Phase 3
21 Estradiol 3-benzoate Phase 4,Phase 3
22 Estradiol 17 beta-cypionate Phase 4,Phase 3
23 Follicle Stimulating Hormone Phase 4
24
Carboplatin Approved Phase 3,Phase 2,Phase 1,Not Applicable 41575-94-4 10339178 38904 498142
25
Vinblastine Approved Phase 3 865-21-4 241903 13342
26
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 6055-19-2, 50-18-0 2907
27
Etoposide Approved Phase 3,Phase 2,Phase 1,Not Applicable 33419-42-0 36462
28
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
29
Granisetron Approved, Investigational Phase 3,Not Applicable 109889-09-0 3510
30
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 33069-62-4 36314
31
Bleomycin Approved, Investigational Phase 3,Phase 2,Not Applicable 11056-06-7 5360373
32
Oxaliplatin Approved, Investigational Phase 3,Phase 2 61825-94-3 43805 6857599 5310940 9887054
33
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2,Not Applicable 51-75-2 4033
34
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1 135968-09-1
35
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
36
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2,Not Applicable 50-02-2 5743
37
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2,Not Applicable 1177-87-3
38
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
39
Ofloxacin Approved Phase 3 82419-36-1 4583
40
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
41
Captopril Approved Phase 3 62571-86-2 44093
42
Ribavirin Approved Phase 3 36791-04-5 37542
43
Palivizumab Approved, Investigational Phase 3 188039-54-5
44
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 22916-47-8 4189
45
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
46
Itraconazole Approved, Investigational Phase 3,Not Applicable 84625-61-6 55283
47
Caspofungin Approved Phase 3,Phase 2 179463-17-3, 162808-62-0 468682 2826718
48
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
49
Acyclovir Approved Phase 3 59277-89-3 2022
50
Promethazine Approved, Investigational Phase 3 60-87-7 4927

Interventional clinical trials:

(show top 50) (show all 289)
# Name Status NCT ID Phase Drugs
1 Taste, Smell and Chemotherapy (TASTY) Completed NCT01641172 Phase 4
2 Effect of Topical Imiquimod on Lentigo Maligna Completed NCT01161888 Phase 4 Imiquimod
3 Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters Recruiting NCT03203681 Phase 4 NATESTO® (4.5% nasal testosterone) Nasal Gel
4 Docetaxel Combined With Carboplatin Plus Anlotinib as First Line Treatment in NSCLC Not yet recruiting NCT03799601 Phase 4 Anlotinib;Docetaxel;Carboplatin
5 Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors Unknown status NCT00002566 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide;ifosfamide;vinblastine sulfate
6 Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle Unknown status NCT00589537 Phase 3
7 Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma Unknown status NCT00004219 Phase 3 granisetron hydrochloride;lerisetron
8 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
9 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
10 Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic Cancer Unknown status NCT01087268 Phase 3
11 Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors Unknown status NCT00274950 Phase 3 carboplatin;cisplatin;etoposide;ifosfamide;vinblastine sulfate
12 Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular Cancer Completed NCT00003014 Phase 3 carboplatin
13 Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles Completed NCT00324298 Phase 3 cisplatin;etoposide
14 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
15 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Completed NCT00053352 Phase 3 cisplatin;etoposide
16 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
17 Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant Completed NCT01305200 Phase 3 supersaturated calcium phosphate rinse
18 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3 levofloxacin
19 Androgen for Leydig Cell Proliferation Completed NCT01206270 Phase 2, Phase 3 Testosterone undecanoate;Castor Oil
20 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
21 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
22 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
23 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
24 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
25 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
26 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
27 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
28 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Completed NCT00716976 Phase 3 sodium thiosulfate
29 Study of Testosterone vs Placebo in Testicular Cancer Survivors Recruiting NCT02991209 Phase 2, Phase 3 Testosterone;Placebos
30 Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer Recruiting NCT02341989 Phase 3 Bleomycin Etoposide and Cisplatin;Carboplatin
31 Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours Recruiting NCT02582697 Phase 3 Bleomycin (active name: Bleomycin Sulfate);Etoposide;Cisplatin;Pegylated G-CSF (Pegfilgrastim);Filgrastim
32 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
33 Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours Active, not recruiting NCT01726374 Phase 3 BEP(500)
34 Hypofractionated, Dose Escalation Radiotherapy for High Risk Adenocarcinoma of the Prostate Active, not recruiting NCT01444820 Phase 3
35 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
36 Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant Terminated NCT00324324 Phase 3 moxifloxacin hydrochloride;Placebo
37 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
38 Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD) Terminated NCT00089141 Phase 3 mycophenolate mofetil;placebo
39 Sorafenib Monotherapy in Inoperable/Recurrent Germ Cell Carcinoma Refractory to Chemotherapy Unknown status NCT00772694 Phase 2 sorafenib
40 Peptide Vaccination in Treating Patients With Esophageal Cancer (STF-II) Unknown status NCT01267578 Phase 2
41 A Study With Peptide Vaccination in Treating Patients With Esophageal Cancer Unknown status NCT00995358 Phase 2
42 Phase II Study of S-488410 to Treat Non-small Cell Lung Cancer Unknown status NCT01592617 Phase 2 S-488410
43 Safety and Efficacy Study of Epitope Peptide To Treat HLA-A*02 Disease Controlled Advanced Non-small Cell Lung Cancer Unknown status NCT01949701 Phase 1, Phase 2
44 Decitabine Followed by Donor Lymphocyte Infusion for Patients With Relapsed Acute Myeloblastic Leukemia(AML) After Allogeneic Stem Cell Transplantation Unknown status NCT01758367 Phase 1, Phase 2 Deciatbine(DAC)
45 Pazopanib in Advanced and Cisplatin-resistant Germ Cell Tumors Unknown status NCT01743482 Phase 2 Pazopanib
46 Promotora-based Latino Family CVD Risk Reduction Unknown status NCT01714271 Phase 2
47 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
48 Trial of Gemcitabine, Cisplatin, and Ifosfamide in Patients With Relapsed Non-Seminomatous Germ-Cell Tumors Unknown status NCT00127049 Phase 2 gemcitabine, ifosfamide, cisplatin, G-CSF
49 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2 carboplatin;cisplatin;dexamethasone;etoposide;ifosfamide
50 Everolimus in Refractory Testicular Germ Cell Cancer Completed NCT01466231 Phase 2 Everolimus

Search NIH Clinical Center for Testicular Germ Cell Cancer

Cochrane evidence based reviews: testicular germ cell tumor

Genetic Tests for Testicular Germ Cell Cancer

Anatomical Context for Testicular Germ Cell Cancer

MalaCards organs/tissues related to Testicular Germ Cell Cancer:

41
Bone, Bone Marrow, Testis, Brain, Lung, Kidney, Lymph Node

Publications for Testicular Germ Cell Cancer

Articles related to Testicular Germ Cell Cancer:

(show top 50) (show all 140)
# Title Authors Year
1
Complex Polygenic Nature of Testicular Germ Cell Cancer Suggests Multifactorial Aetiology. ( 29530636 )
2018
2
Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer? ( 29179257 )
2018
3
CK7, inhibin, and p63 in testicular germ cell tumor: superior markers of Choriocarcinoma compared to β-hCG. ( 30359635 )
2018
4
Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor. ( 30041955 )
2018
5
Risk of Solid Cancer After Treatment of Testicular Germ Cell Cancer in the Platinum Era. ( 29989856 )
2018
6
ESMO Consensus Conference on testicular germ cell cancer: diagnosis, treatment and follow-up. ( 30113631 )
2018
7
Seminoma component of mixed testicular germ cell tumor shows a higher incidence of loss of heterozygosity than pure-type seminoma. ( 30266250 )
2018
8
Re: Identification of 19 New Risk Loci and Potential Regulatory Mechanisms Influencing Susceptibility to Testicular Germ Cell Tumor. ( 30227584 )
2018
9
A miR-125b/CSF1-CX3CL1/tumor-associated macrophage recruitment axis controls testicular germ cell tumor growth. ( 30237497 )
2018
10
MiR-371a-3p Serum Levels Are Increased in Recurrence of Testicular Germ Cell Tumor Patients. ( 30321995 )
2018
11
Clinicopathological Significance and Antitumor Effect of MPHOSPH1 in Testicular Germ Cell Tumor. ( 30519350 )
2018
12
microRNA-371a-3p as informative biomarker for the follow-up of testicular germ cell cancer patients. ( 28612337 )
2017
13
Cisplatin-related Cerebral Infarction in Testicular Germ Cell Cancer: Short Report of Three Cases and P in testicular germ cell cancer: Short report of three cases and pathomechanism. ( 27923208 )
2017
14
Risk of low bone mineral density in testicular germ cell cancer survivors: association with hypogonadism and treatment modality. ( 28591464 )
2017
15
Animacroxam, a novel dual-mode compound targeting histone deacetylases and cytoskeletal integrity of testicular germ cell cancer cells. ( 28838999 )
2017
16
MGMT and CALCA promoter methylation are associated with poor prognosis in testicular germ cell tumor patients. ( 28881587 )
2017
17
A Brief Review of the Link between Environment and Male Reproductive Health: Lessons from Studies of Testicular Germ Cell Cancer. ( 26871895 )
2016
18
Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review. ( 27821802 )
2016
19
Androgen receptor gene CAG and GGN repeat lengths as predictors of recovery of spermatogenesis following testicular germ cell cancer treatment. ( 27873769 )
2016
20
Testicular germ cell tumor: Short and long-term side effects of treatment among survivors. ( 27588190 )
2016
21
Increasing international efforts to understand and conquer testicular germ cell cancer. ( 25711179 )
2015
22
Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship. ( 25751759 )
2015
23
Re: Yvonne Vergouwe, Ewout W. Steyerberg, Richard S. Foster, et al. Predicting Retroperitoneal Histology in Postchemotherapy Testicular Germ Cell Cancer: A Model Update and Multicentre Validation with More Than 1000 Patients. Eur Urol 2007;51:424-32. ( 26726125 )
2015
24
Reply to Nahid Punjani, Nicholas Power, Eric Winquist's Letter to the Editor re: Yvonne Vergouwe, Ewout W. Steyerberg, Richard S. Foster, et al. Predicting Retroperitoneal Histology in Postchemotherapy Testicular Germ Cell Cancer: A Model Update and Multicentre Validation with More Than 1000 Patients. Eur Urol 2007;51:424-32. ( 26726124 )
2015
25
Muscle-building supplement use and increased risk of testicular germ cell cancer in men from Connecticut and Massachusetts. ( 25826226 )
2015
26
Surveillance policy for Japanese patients with stage I testicular germ cell cancer in the multi-detector computed tomography era. ( 25893862 )
2015
27
Salvage chemotherapy with gemcitabine plus oxaliplatin for patients with testicular germ cell cancer. ( 24647526 )
2014
28
Trends in testicular germ cell cancer incidence in Eastern Croatia. ( 24496357 )
2014
29
An oncofetal and developmental perspective on testicular germ cell cancer. ( 25066859 )
2014
30
Changes in epidemiologic features of testicular germ cell cancer: Age at diagnosis and relative frequency of seminoma are constantly and significantly increasing. ( 23395239 )
2014
31
Circulating Serum miRNA (miR-367-3p, miR-371a-3p, miR-372-3p and miR-373-3p) as Biomarkers in Patients with Testicular Germ Cell Cancer. ( 25046619 )
2014
32
Nodal, pulmonary and pleural gliomatosis in a 42-year-old-male with non-seminomatous testicular germ cell cancer. ( 24444134 )
2014
33
Cutaneous angiosarcoma at an interval of thirty-six years from radiation for a testicular germ cell tumor. ( 25179148 )
2014
34
Mesenteric lymphadenopathy in testicular germ cell tumor. ( 24418390 )
2014
35
Thrombocytopenia following high-dose chemotherapy with carboplatin, etoposide and thiotepa in patients with testicular germ cell cancer. ( 23260006 )
2013
36
Expression analysis of RNA-binding motif gene on Y chromosome (RBMY) protein isoforms in testis tissue and a testicular germ cell cancer-derived cell line (NT2). ( 23567846 )
2013
37
Just another brick in the wall: unravelling the epigenetic mechanism underlying tumour initiation of testicular germ cell cancer. ( 24292446 )
2013
38
Association between polymorphisms in the aryl hydrocarbon receptor repressor gene and disseminated testicular germ cell cancer. ( 23420531 )
2013
39
Re: Anti-tumour activity of two novel compounds in cisplatin-resistant testicular germ cell cancer. ( 24120784 )
2013
40
Sperm concentration, testicular volume and age predict risk of carcinoma in situ in contralateral testis of men with testicular germ cell cancer. ( 23770148 )
2013
41
Influence of vitamin D on cisplatin sensitivity in testicular germ cell cancer-derived cell lines and in a NTera2 xenograft model. ( 23098692 )
2013
42
Targeted serum miRNA (TSmiR) test for diagnosis and follow-up of (testicular) germ cell cancer patients: a proof of principle. ( 24012110 )
2013
43
Changing epidemiologic features of testicular germ cell cancer in Germany: corroboration at population level. ( 24035419 )
2013
44
Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer. ( 23372565 )
2013
45
Replication of genetic susceptibility loci for testicular germ cell cancer in the Croatian population. ( 22745383 )
2012
46
Anti-tumour activity of two novel compounds in cisplatin-resistant testicular germ cell cancer. ( 23169338 )
2012
47
Association of polymorphisms in genes encoding hormone receptors ESR1, ESR2 and LHCGR with the risk and clinical features of testicular germ cell cancer. ( 22245602 )
2012
48
Variants in KITLG predispose to testicular germ cell cancer independently from spermatogenic function. ( 22194441 )
2012
49
Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability. ( 22923694 )
2012
50
Is testicular germ cell cancer associated with increased muscle mass or adiposity? ( 21253772 )
2011

Variations for Testicular Germ Cell Cancer

Expression for Testicular Germ Cell Cancer

Search GEO for disease gene expression data for Testicular Germ Cell Cancer.

Pathways for Testicular Germ Cell Cancer

GO Terms for Testicular Germ Cell Cancer

Biological processes related to Testicular Germ Cell Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sex differentiation GO:0007548 8.96 AR DMRT1
2 male gonad development GO:0008584 8.8 AR DMRT1 KITLG

Molecular functions related to Testicular Germ Cell Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone receptor activity GO:0003707 9.16 AR ESR2
2 nuclear receptor activity GO:0004879 8.96 AR ESR2
3 steroid binding GO:0005496 8.62 AR ESR2

Sources for Testicular Germ Cell Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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