MCID: TST007
MIFTS: 25

Testicular Infarct

Categories: Endocrine diseases, Reproductive diseases

Aliases & Classifications for Testicular Infarct

MalaCards integrated aliases for Testicular Infarct:

Name: Testicular Infarct 12 15
Infarction of Testis 12 71
Testicular Infarction 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5104
NCIt 49 C27617
SNOMED-CT 67 33793000
UMLS 71 C0392041

Summaries for Testicular Infarct

MalaCards based summary : Testicular Infarct, also known as infarction of testis, is related to epididymo-orchitis and testicular torsion. An important gene associated with Testicular Infarct is DEFB121 (Defensin Beta 121), and among its related pathways/superpathways is Defensins. The drugs Antibiotics, Antitubercular and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include testis, ovary and appendix.

Related Diseases for Testicular Infarct

Diseases related to Testicular Infarct via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 59, show less)
# Related Disease Score Top Affiliating Genes
1 epididymo-orchitis 29.8 DEFB121 CRP AFP
2 testicular torsion 10.3
3 inguinal hernia 10.3
4 orchitis 10.3
5 vasculitis 10.1
6 sickle cell disease 10.1
7 testicular cancer 10.0
8 purpura 10.0
9 sickle cell anemia 9.9
10 deficiency anemia 9.9
11 protein s deficiency 9.9
12 hemangioma 9.9
13 aortic aneurysm 9.9
14 polyarteritis nodosa 9.9
15 hydrocele 9.9
16 malakoplakia 9.9
17 aneurysm 9.9
18 liver inflammatory pseudotumor 9.9 CRP AFP
19 infected hydrocele 9.9 CRP AFP
20 tuberculous epididymitis 9.9 CRP AFP
21 hepatic vascular disease 9.9 CRP AFP
22 portal vein thrombosis 9.8 CRP AFP
23 vein disease 9.8 CRP AFP
24 buerger disease 9.8
25 placenta disease 9.8 CRP AFP
26 aortic aneurysm, familial abdominal, 1 9.8
27 pulmonary disease, chronic obstructive 9.8
28 antithrombin iii deficiency 9.8
29 hydrops, lactic acidosis, and sideroblastic anemia 9.8
30 peripheral vascular disease 9.8
31 exanthem 9.8
32 endocarditis 9.8
33 cholesterol embolism 9.8
34 thrombophilia 9.8
35 hemoglobinopathy 9.8
36 glomerulonephritis 9.8
37 iga glomerulonephritis 9.8
38 angiomyolipoma 9.8
39 cellulitis 9.8
40 cavernous hemangioma 9.8
41 b-cell lymphoma 9.8
42 kidney angiomyolipoma 9.8
43 polycythemia 9.8
44 intestinal obstruction 9.8
45 mucormycosis 9.8
46 neuropathy 9.8
47 priapism 9.8
48 47,xyy 9.8
49 fournier gangrene 9.8
50 multifocal motor neuropathy 9.8
51 spasticity 9.8
52 spinal cord injury 9.8
53 bile duct disease 9.8 CRP AFP
54 gallbladder disease 9.7 CRP AFP
55 biliary tract disease 9.7 CRP AFP
56 viral hepatitis 9.6 CRP AFP
57 pre-eclampsia 9.4 CRP C19orf33 AFP
58 epididymis disease 9.4 DEFB127 DEFB121 CRP AFP
59 patent foramen ovale 9.3 CRP CLIP3

Graphical network of the top 20 diseases related to Testicular Infarct:



Diseases related to Testicular Infarct

Symptoms & Phenotypes for Testicular Infarct

Drugs & Therapeutics for Testicular Infarct

Drugs for Testicular Infarct (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 2, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibiotics, Antitubercular
2 Anti-Bacterial Agents

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Paediatric Surgery Across Sub-Saharan Africa: A Multi-Centre Prospective Cohort Study Completed NCT03185637

Search NIH Clinical Center for Testicular Infarct

Genetic Tests for Testicular Infarct

Anatomical Context for Testicular Infarct

MalaCards organs/tissues related to Testicular Infarct:

40
Testis, Ovary, Appendix, Spinal Cord, Kidney, Liver, Placenta

Publications for Testicular Infarct

Articles related to Testicular Infarct:

(showing 25, show less)
# Title Authors PMID Year
1
[Rare clinical course of epididymo-orchitis with subtotal testicular infarct]. 61
26114253 2015
2
Identify Before Orchiectomy: Segmental Testicular Infarct. 61
25945726 2015
3
Segmental testicular infarction due to minocycline-induced antineutrophil cytoplasmic antibody--positive vasculitis. 61
24793001 2014
4
Multidrug resistant epididymitis progressing to testicular infarct and orchiectomy. 61
24379982 2013
5
Imaging of non-neoplastic intratesticular masses. 61
20677130 2011
6
Segmental Infarction of Testis: A rare complication of acute epididymitis. 61
28845218 2010
7
US MR imaging correlation in pathologic conditions of the scrotum. 61
17848688 2007
8
Localized traumatic infarction of the testicle. 61
15764261 2004
9
[A rare case of acute scrotum. Thrombophlebitis from ectasia of the left pampiniforme plexus]. 61
10638181 1999
10
[Isolated vasculitis of the spermatic cord]. 61
10510712 1999
11
Segmental hemorrhagic infarction of testis associated with epididymitis. 61
9641396 1998
12
[Testicular infarct simulating a neoplasms]. 61
9586321 1998
13
[Testicular infarction as a cause of benign intrascrotal tumor]. 61
8678606 1996
14
Oversized "bullseye" with central activity. A scintigraphic appearance of hemorrhagic testicular infarct following traumatic rupture of the testicle. 61
8403724 1993
15
[Segmental ischemic testicular infarct. The echographic and histological correlations]. 61
2697036 1989
16
[Testicular echography in torsion and epididymitis. Apropos of 2 cases]. 61
3058956 1988
17
Postsurgical focal testicular infarct. 61
3727192 1986
18
[A case of bilateral testicular infarction without spermatic torsion]. 61
6507211 1984
19
[Testicular infarct secondary to strangulated inguinal hernia in childhood]. 61
7360353 1980
20
[Irreversible infarction of testis and ovary due to incarcerated inguinal hernia in the newborn]. 61
888586 1977
21
[Differential diagnosis: testicular neoplasms--idiopathic testicular infarct]. 61
5758809 1968
22
[Testicular infarct in rheumatoid purpura]. 61
5619178 1967
23
Total granulomatous infarction of testis due to Schistosoma haematobium. 61
5602560 1967
24
Hemorrhagic infarction of testis in newborn; relationship to testicular torsion. 61
13227600 1955
25
[Testicular infarct and torsion of the appendix testis in children]. 61
14942149 1952

Variations for Testicular Infarct

Expression for Testicular Infarct

Search GEO for disease gene expression data for Testicular Infarct.

Pathways for Testicular Infarct

Pathways related to Testicular Infarct according to GeneCards Suite gene sharing:

(showing 1, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.13 DEFB129 DEFB127 DEFB121

GO Terms for Testicular Infarct

Cellular components related to Testicular Infarct according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.02 DEFB129 DEFB127 DEFB121 CRP AFP

Biological processes related to Testicular Infarct according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.33 DEFB129 DEFB127 DEFB121
2 innate immune response GO:0045087 9.26 DEFB129 DEFB127 DEFB121 CRP
3 defense response GO:0006952 8.8 DEFB129 DEFB127 DEFB121

Sources for Testicular Infarct

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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