MCID: TST017
MIFTS: 17

Testicular Malignant Germ Cell Cancer

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Testicular Malignant Germ Cell Cancer

MalaCards integrated aliases for Testicular Malignant Germ Cell Cancer:

Name: Testicular Malignant Germ Cell Cancer 12 15
Malignant Germ Cell Tumor of Testis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5556
NCIt 50 C9063
SNOMED-CT 68 713646001
UMLS 73 C0855197

Summaries for Testicular Malignant Germ Cell Cancer

MalaCards based summary : Testicular Malignant Germ Cell Cancer, also known as malignant germ cell tumor of testis, is related to endodermal sinus tumor and dysgerminoma of ovary. An important gene associated with Testicular Malignant Germ Cell Cancer is AFP (Alpha Fetoprotein), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include testis.

Related Diseases for Testicular Malignant Germ Cell Cancer

Diseases in the Testicular Germ Cell Cancer family:

Testicular Malignant Germ Cell Cancer

Diseases related to Testicular Malignant Germ Cell Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 endodermal sinus tumor 10.0 AFP ALPP
2 dysgerminoma of ovary 10.0 AFP ALPP
3 testicular cancer 10.0 AFP ALPP
4 seminoma 9.9 AFP ALPP
5 ovarian embryonal carcinoma 9.9 AFP GPC3
6 hepatic adenomas, familial 9.9 AFP GPC3
7 seminal vesicle tumor 9.8 AFP GPC3
8 ovarian endodermal sinus tumor 9.8 AFP GPC3
9 ovarian primitive germ cell tumor 9.8 AFP GPC3
10 bile duct adenocarcinoma 9.8 AFP GPC3
11 testicular germ cell tumor 9.7 AFP GPC3
12 gastrointestinal system cancer 9.7 AFP GPC3
13 ovarian clear cell carcinoma 9.6 GPC3 NAPSA
14 hepatoblastoma 9.6 AFP GPC3
15 liver cirrhosis 9.5 AFP GPC3
16 testis seminoma 9.4 ALPP DNMT3L SLC2A5
17 beckwith-wiedemann syndrome 9.4 AFP GPC3
18 choriocarcinoma 9.3 ALPP GPC3
19 testicular yolk sac tumor 9.3 AFP GPC3 NAPSA
20 lung squamous cell carcinoma 9.0 GPC3 NAPSA

Graphical network of the top 20 diseases related to Testicular Malignant Germ Cell Cancer:



Diseases related to Testicular Malignant Germ Cell Cancer

Symptoms & Phenotypes for Testicular Malignant Germ Cell Cancer

Drugs & Therapeutics for Testicular Malignant Germ Cell Cancer

Search Clinical Trials , NIH Clinical Center for Testicular Malignant Germ Cell Cancer

Genetic Tests for Testicular Malignant Germ Cell Cancer

Anatomical Context for Testicular Malignant Germ Cell Cancer

MalaCards organs/tissues related to Testicular Malignant Germ Cell Cancer:

41
Testis

Publications for Testicular Malignant Germ Cell Cancer

Variations for Testicular Malignant Germ Cell Cancer

Expression for Testicular Malignant Germ Cell Cancer

Search GEO for disease gene expression data for Testicular Malignant Germ Cell Cancer.

Pathways for Testicular Malignant Germ Cell Cancer

Pathways related to Testicular Malignant Germ Cell Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.75 AFP ALPP

GO Terms for Testicular Malignant Germ Cell Cancer

Cellular components related to Testicular Malignant Germ Cell Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anchored component of membrane GO:0031225 8.62 ALPP GPC3

Biological processes related to Testicular Malignant Germ Cell Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.8 AFP GPC3 NAPSA

Sources for Testicular Malignant Germ Cell Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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