MCID: TST025
MIFTS: 28

Testicular Microlithiasis

Categories: Reproductive diseases

Aliases & Classifications for Testicular Microlithiasis

MalaCards integrated aliases for Testicular Microlithiasis:

Name: Testicular Microlithiasis 57 29 13 40 73

Classifications:



External Ids:

OMIM 57 610441
MedGen 42 C1864873
SNOMED-CT via HPO 69 117261000119108
UMLS 73 C1864873

Summaries for Testicular Microlithiasis

OMIM : 57 Testicular microlithiasis, the deposition of calcium phosphate microliths within the seminiferous tubules, has a population prevalence of 0.6 to 9% (Kim et al., 2003). Middleton et al. (2002) found that it was associated with a majority of primary testicular malignancies. Miller and Sidhu (2002) found that it was present in 1% of male idiopathic infertility cases. (610441)

MalaCards based summary : Testicular Microlithiasis is related to germ cells tumors and testicular cancer. An important gene associated with Testicular Microlithiasis is SLC34A2 (Solute Carrier Family 34 Member 2). Affiliated tissues include testes, testis and appendix, and related phenotype is testicular microlithiasis.

Wikipedia : 76 Testicular microlithiasis is an unusual condition diagnosed on testicular ultrasound. It is found in... more...

Related Diseases for Testicular Microlithiasis

Graphical network of the top 20 diseases related to Testicular Microlithiasis:



Diseases related to Testicular Microlithiasis

Symptoms & Phenotypes for Testicular Microlithiasis

Clinical features from OMIM:

610441

Human phenotypes related to Testicular Microlithiasis:

32
# Description HPO Frequency HPO Source Accession
1 testicular microlithiasis 32 HP:0012215

Drugs & Therapeutics for Testicular Microlithiasis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Identification of Predictive Markers for Testis Cancer in a Population of Men With High Risk Terminated NCT00820287 Not Applicable

Search NIH Clinical Center for Testicular Microlithiasis

Genetic Tests for Testicular Microlithiasis

Genetic tests related to Testicular Microlithiasis:

# Genetic test Affiliating Genes
1 Testicular Microlithiasis 29 SLC34A2

Anatomical Context for Testicular Microlithiasis

MalaCards organs/tissues related to Testicular Microlithiasis:

41
Testes, Testis, Appendix, Adrenal Gland, Spleen

Publications for Testicular Microlithiasis

Articles related to Testicular Microlithiasis:

(show top 50) (show all 235)
# Title Authors Year
1
Testicular microlithiasis in a clinically healthy cynomolgus monkey (<i>Macaca fascicularis</i>). ( 29750004 )
2018
2
Adolescent testicular microlithiasis: A case-based, multinational survey of clinical management practices. ( 29428360 )
2018
3
Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark. ( 29510806 )
2018
4
Prevalence and risk factors of testicular microlithiasis in patients with hypospadias: a retrospective study. ( 29843681 )
2018
5
A case of Riley Ruvalcaba syndrome with a novel PTEN mutation accompanied by diffuse testicular microlithiasis and precocious puberty. ( 29194042 )
2018
6
Elastography and diffusion-weighted MRI in patients with testicular microlithiasis, normal testicular tissue, and testicular cancer: an observational study. ( 29969051 )
2018
7
European Society of Paediatric Radiology Abdominal Imaging Task Force recommendations in paediatric uroradiology, part X: how to perform paediatric gastrointestinal ultrasonography, use gadolinium as a contrast agent in children, follow up paediatric testicular microlithiasis, and an update on paediatric contrast-enhanced ultrasound. ( 29796794 )
2018
8
The role of ARFI elastography to evaluate microstructrual changes of patients with testicular microlithiasis. ( 29566548 )
2018
9
Prevalence and Chronological Changes of Testicular Microlithiasis in Isolated Congenital Undescended Testes Operated On at Less Than 3 Years of Age. ( 28780301 )
2017
10
Role of calcifying nanoparticles in the development of testicular microlithiasis in vivo. ( 29084530 )
2017
11
Pediatric Testicular Microlithiasis: To Refer or Not to Refer? ( 29051915 )
2017
12
Testicular Adrenal Rests Tumors and Testicular Microlithiasis in a Brazilian Case Series with Classic Congenital Adrenal Hyperplasia. ( 28835760 )
2017
13
Association between Testicular Microlithiasis and Testicular Neoplasia: Large Multicenter Study in a Pediatric Population. ( 28715257 )
2017
14
Comparison of Tissue Stiffness Using Shear Wave Elastography in Men with Normal Testicular Tissue, Testicular Microlithiasis and Testicular Cancer. ( 29276802 )
2017
15
Testicular microlithiasis is associated with ethnicity and socioeconomic status. ( 28815058 )
2017
16
Bilateral methachronous testicular germ cell tumor and testicular microlithiasis in a child: Genetic analysis and insights. A case report. ( 29040905 )
2017
17
Shear wave elastography evaluation in pediatric testicular microlithiasis: a comparative study. ( 29075915 )
2017
18
Characteristics of symptomatic men with testicular microlithiasis - A Danish cross-sectional questionnaire study. ( 28267895 )
2017
19
Testicular Microlithiasis in the Setting of Primary Extragonadal Germ Cell Tumor: A Case Series. ( 27599309 )
2016
20
Testicular microlithiasis and testicular cancer: review of the literature. ( 27007613 )
2016
21
Inter- and intraobserver agreement in detection of testicular microlithiasis with ultrasonography. ( 26419255 )
2016
22
Testicular Microlithiasis: Patient Compliance in a Two-Year Follow-Up Program. ( 27921092 )
2016
23
Testicular microlithiasis: Correlation with doppler sonography of testicular arteries and sperm function. ( 27120130 )
2016
24
The influence of testicular microlithiasis on the outcomes of in vitro fertilisation in a Chinese Han population. ( 27882628 )
2016
25
Testicular microlithiasis and preliminary experience of acoustic radiation force impulse imaging. ( 27504193 )
2016
26
Re: Ultrasound Demonstration of Testicular Microlithiasis in Pediatric Patients: Is There an Association with Testicular Germ Cell Tumors? ( 27321534 )
2016
27
Unilateral testicular microlithiasis: a rare paediatric incidental finding. ( 27613265 )
2016
28
Double Para-testicular Cellular Angiofibroma and Synchronous Testicular Microlithiasis. ( 26265690 )
2016
29
How should we monitor boys with testicular microlithiasis? ( 27007453 )
2016
30
Testicular Microlithiasis: What Should You Recommend? ( 27058778 )
2016
31
Long-Term Follow-Up of Testicular Microlithiasis in Children and Adolescents: Multicenter Prospective Cohort Study of the Italian Society of Pediatric Urology. ( 26962678 )
2016
32
Re: Testicular Microlithiasis Imaging and Follow-up: Guidelines of the ESUR Scrotal Imaging Subcommittee. ( 27597076 )
2016
33
Incidence of testicular microlithiasis in patients with I^-thalassemia major. ( 26251156 )
2015
34
Changes of calcific density in pediatric patients with testicular microlithiasis. ( 25874046 )
2015
35
Testicular Microlithiasis: Is Sonographic Surveillance Necessary? Single Centre 14 Year Experience in 442 Patients with Testicular Microlithiasis. ( 25654622 )
2015
36
Testicular microlithiasis and associated testicular malignancies in childhood: a systematic review. ( 25417839 )
2015
37
Partial Orchiectomy for the Treatment of a Benign Sclerosing Sertoli Cell Tumor: A Report of a Rare Tumor in Association With Testicular Microlithiasis. ( 26793488 )
2015
38
Attributable risk calculations for testicular microlithiasis. ( 25502584 )
2015
39
A Meta-Analysis of the Relationship between Testicular Microlithiasis and Incidence of Testicular Cancer. ( 25923148 )
2015
40
Testicular microlithiasis: prevalence and association with primary testicular neoplasm. ( 24585495 )
2014
41
Re: Testicular Microlithiasis: Is there a Need for Surveillance in the Absence of Other Risk Factors? ( 24331488 )
2014
42
Coexistence of testicular microlithiasis with parathyroid adenoma in an obese child. ( 24030026 )
2014
43
A case report of transverse testicular ectopia with testicular microlithiasis. ( 25380032 )
2014
44
Testicular microlithiasis. ( 24684881 )
2014
45
Testicular microlithiasis and dyspermia: is there any correlation? ( 24704926 )
2014
46
The association between testicular microlithiasis and semen parameters in Chinese adult men with fertility intention: experience of 226 cases. ( 25129542 )
2014
47
Testicular microlithiasis in children and associated testicular cancer. ( 24475810 )
2014
48
Ultrasound demonstration of testicular microlithiasis in pediatric patients: is there an association with testicular germ cell tumors? ( 24026852 )
2014
49
Re: germ cell tumor in an adolescent with extensive testicular microlithiasis: concerns regarding future management, and re: clinical aspects of testicular microlithiasis in boys: a review. ( 25280322 )
2014
50
Testicular microlithiasis imaging and follow-up: guidelines of the ESUR scrotal imaging subcommittee. ( 25316054 )
2014

Variations for Testicular Microlithiasis

Expression for Testicular Microlithiasis

Search GEO for disease gene expression data for Testicular Microlithiasis.

Pathways for Testicular Microlithiasis

GO Terms for Testicular Microlithiasis

Biological processes related to Testicular Microlithiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.62 AFP SLC34A2

Sources for Testicular Microlithiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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