MCID: TST013
MIFTS: 17

Testicular Thecoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Testicular Thecoma

MalaCards integrated aliases for Testicular Thecoma:

Name: Testicular Thecoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:7676
NCIt 50 C39952
UMLS 71 C1515299

Summaries for Testicular Thecoma

MalaCards based summary : Testicular Thecoma is related to 46,xy partial gonadal dysgenesis and 46,xy sex reversal 9. An important gene associated with Testicular Thecoma is PTCH1 (Patched 1). Related phenotypes are cardiovascular system and muscle

Related Diseases for Testicular Thecoma

Graphical network of the top 20 diseases related to Testicular Thecoma:



Diseases related to Testicular Thecoma

Symptoms & Phenotypes for Testicular Thecoma

MGI Mouse Phenotypes related to Testicular Thecoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.63 CLMP GATA4 GJC3 GJD3 PTCH1 ZFPM2
2 muscle MP:0005369 9.26 CLMP GATA4 PTCH1 ZFPM2
3 no phenotypic analysis MP:0003012 8.92 GATA4 GJD3 PTCH1 ZFPM2

Drugs & Therapeutics for Testicular Thecoma

Search Clinical Trials , NIH Clinical Center for Testicular Thecoma

Genetic Tests for Testicular Thecoma

Anatomical Context for Testicular Thecoma

Publications for Testicular Thecoma

Articles related to Testicular Thecoma:

# Title Authors PMID Year
1
Testicular thecoma in an 11-year-old boy with nevoid basal-cell carcinoma syndrome (Gorlin syndrome). 61
20223301 2010

Variations for Testicular Thecoma

Expression for Testicular Thecoma

Search GEO for disease gene expression data for Testicular Thecoma.

Pathways for Testicular Thecoma

GO Terms for Testicular Thecoma

Cellular components related to Testicular Thecoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 gap junction GO:0005921 8.96 GJD3 GJC3
2 connexin complex GO:0005922 8.62 GJD3 GJC3

Biological processes related to Testicular Thecoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to mechanical stimulus GO:0009612 9.32 PTCH1 GATA4
2 cell communication GO:0007154 9.26 GJD3 GJC3
3 embryonic organ development GO:0048568 9.16 ZFPM2 PTCH1
4 cell-cell signaling GO:0007267 9.13 GJD3 GJC3 GATA4
5 AV node cell to bundle of His cell communication by electrical coupling GO:0086053 8.62 GJD3 GJC3

Molecular functions related to Testicular Thecoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II transcription factor binding GO:0001085 9.16 ZFPM2 GATA4
2 gap junction channel activity GO:0005243 8.96 GJD3 GJC3
3 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling GO:0086077 8.62 GJD3 GJC3

Sources for Testicular Thecoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....