MCID: TST040
MIFTS: 17

Testicular Trophoblastic Tumor

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Testicular Trophoblastic Tumor

MalaCards integrated aliases for Testicular Trophoblastic Tumor:

Name: Testicular Trophoblastic Tumor 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4084
NCIt 50 C39934
UMLS 70 C1515301

Summaries for Testicular Trophoblastic Tumor

MalaCards based summary : Testicular Trophoblastic Tumor is related to gestational ovarian choriocarcinoma and choriocarcinoma. An important gene associated with Testicular Trophoblastic Tumor is CSH1 (Chorionic Somatomammotropin Hormone 1), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Relaxin signaling pathway. Affiliated tissues include testis.

Related Diseases for Testicular Trophoblastic Tumor

Graphical network of the top 20 diseases related to Testicular Trophoblastic Tumor:



Diseases related to Testicular Trophoblastic Tumor

Symptoms & Phenotypes for Testicular Trophoblastic Tumor

Drugs & Therapeutics for Testicular Trophoblastic Tumor

Search Clinical Trials , NIH Clinical Center for Testicular Trophoblastic Tumor

Genetic Tests for Testicular Trophoblastic Tumor

Anatomical Context for Testicular Trophoblastic Tumor

MalaCards organs/tissues related to Testicular Trophoblastic Tumor:

40
Testis

Publications for Testicular Trophoblastic Tumor

Articles related to Testicular Trophoblastic Tumor:

# Title Authors PMID Year
1
Trophoblastic tumors of the testis other than classic choriocarcinoma: "monophasic" choriocarcinoma and placental site trophoblastic tumor: a report of two cases. 61
9060597 1997

Variations for Testicular Trophoblastic Tumor

Expression for Testicular Trophoblastic Tumor

Search GEO for disease gene expression data for Testicular Trophoblastic Tumor.

Pathways for Testicular Trophoblastic Tumor

Pathways related to Testicular Trophoblastic Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.09 CSH2 CSH1
2
Show member pathways
11.75 CSH2 CSH1
3
Show member pathways
11.41 CSH2 CSH1
4
Show member pathways
11.02 CSH2 CSH1

GO Terms for Testicular Trophoblastic Tumor

Cellular components related to Testicular Trophoblastic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vesicle GO:0031982 8.62 CSH2 CSH1

Biological processes related to Testicular Trophoblastic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to nutrient levels GO:0031667 9.37 CSH2 CSH1
2 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.32 CSH2 CSH1
3 positive regulation of JAK-STAT cascade GO:0046427 9.26 CSH2 CSH1
4 animal organ development GO:0048513 9.16 CSH2 CSH1
5 growth hormone receptor signaling pathway GO:0060396 8.96 CSH2 CSH1
6 positive regulation of growth GO:0045927 8.62 CSH2 CSH1

Molecular functions related to Testicular Trophoblastic Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.16 CSH2 CSH1
2 hormone activity GO:0005179 8.96 CSH2 CSH1
3 growth hormone receptor binding GO:0005131 8.62 CSH2 CSH1

Sources for Testicular Trophoblastic Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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