Testicular Yolk Sac Tumor

Categories: Cancer diseases, Endocrine diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Testicular Yolk Sac Tumor

MalaCards integrated aliases for Testicular Yolk Sac Tumor:

Name: Testicular Yolk Sac Tumor 12 53 55 15 17 72
Testicular Yolk Sac Neoplasm 12
Endodermal-Sinus Tumor 53
Orchidoblastoma 53
Yolk Sac Tumor 72


External Ids:

Disease Ontology 12 DOID:5344
NCIt 50 C8000
UMLS 72 C0014145 C0279708

Summaries for Testicular Yolk Sac Tumor

MalaCards based summary : Testicular Yolk Sac Tumor, also known as testicular yolk sac neoplasm, is related to childhood endodermal sinus tumor and ovarian endodermal sinus tumor. An important gene associated with Testicular Yolk Sac Tumor is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Wnt / Hedgehog / Notch and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Ribavirin and Palivizumab have been mentioned in the context of this disorder. Affiliated tissues include testis, ovary and bone, and related phenotype is homeostasis/metabolism.

Related Diseases for Testicular Yolk Sac Tumor

Diseases related to Testicular Yolk Sac Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)
# Related Disease Score Top Affiliating Genes
1 childhood endodermal sinus tumor 12.9
2 ovarian endodermal sinus tumor 12.8
3 adult endodermal sinus tumor 12.8
4 childhood ovarian endodermal sinus tumor 12.8
5 mediastinal endodermal sinus tumors 12.7
6 macrocystic pattern testicular yolk sac tumor 12.6
7 solid pattern testicular yolk sac tumor 12.6
8 glandular-alveolar pattern testicular yolk sac tumor 12.6
9 myxomatous pattern testicular yolk sac tumor 12.6
10 papillary pattern testicular yolk sac tumor 12.6
11 enteric pattern testicular yolk sac tumor 12.6
12 reticular pattern testicular yolk sac tumor 12.6
13 central nervous system endodermal sinus tumor 12.6
14 endodermal sinus pattern testicular yolk sac tumor 12.6
15 polyvesicular vitelline pattern testicular yolk sac tumor 12.6
16 hepatoid pattern testicular yolk sac tumor 12.6
17 testicular germ cell tumor 12.0
18 yolk sac tumor of central nervous system 11.8
19 glandular pattern ovarian yolk sac tumor 11.5
20 hepatoid pattern ovarian yolk sac tumor 11.5
21 polyvesicular vitelline pattern ovarian yolk sac tumor 11.5
22 germ cells tumors 10.9
23 endodermal sinus tumor 10.8
24 germ cell cancer 10.6
25 pineoblastoma 10.5
26 pineal gland cancer 10.5
27 pineocytoma 10.5
28 rare tumor 10.5
29 clear cell adenocarcinoma 10.4
30 sacrococcygeal teratoma 10.4
31 cystic teratoma 10.4
32 rhabdomyosarcoma 10.4
33 botryoid rhabdomyosarcoma 10.4
34 dysgerminoma 10.4
35 ovarian embryonal carcinoma 10.4
36 adenocarcinoma 10.3
37 gastric adenocarcinoma 10.3
38 mixed germ cell tumor 10.3
39 ataxia and polyneuropathy, adult-onset 10.2
40 aceruloplasminemia 10.2
41 hydrocephalus 10.2
42 thrombocytopenia 10.2
43 transitional cell carcinoma 10.2
44 endometrial adenocarcinoma 10.2
45 testicular cancer 10.2
46 choriocarcinoma 10.2
47 malignant teratoma 10.2
48 ovarian mixed germ cell neoplasm 10.2
49 exophthalmos 10.2
50 congenital hydrocephalus 10.2

Graphical network of the top 20 diseases related to Testicular Yolk Sac Tumor:

Diseases related to Testicular Yolk Sac Tumor

Symptoms & Phenotypes for Testicular Yolk Sac Tumor

MGI Mouse Phenotypes related to Testicular Yolk Sac Tumor:

# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.02 AFP AHSG HP RUNX3 TF

Drugs & Therapeutics for Testicular Yolk Sac Tumor

Drugs for Testicular Yolk Sac Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 158)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Ribavirin Approved Phase 3 36791-04-5 37542
Palivizumab Approved, Investigational Phase 3 188039-54-5
Captopril Approved Phase 3 62571-86-2 44093
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
Ondansetron Approved Phase 3 99614-02-5 4595
Bleomycin Approved, Investigational Phase 3 11056-06-7 5360373
Mesna Approved, Investigational Phase 3 3375-50-6 598
Promethazine Approved, Investigational Phase 3 60-87-7 4927
Diphenhydramine Approved, Investigational Phase 3 58-73-1, 147-24-0 3100
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
Ifosfamide Approved Phase 3 3778-73-2 3690
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
Mechlorethamine Approved, Investigational Phase 3 51-75-2 4033
Vinblastine Approved Phase 3 865-21-4 241903 13342
20 Antibodies Phase 3
21 Antibodies, Monoclonal Phase 3
22 Immunoglobulins Phase 3
23 Antimetabolites Phase 3
24 Antihypertensive Agents Phase 3
25 Angiotensin-Converting Enzyme Inhibitors Phase 3
26 14-alpha Demethylase Inhibitors Phase 3
27 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
28 Cytochrome P-450 CYP3A Inhibitors Phase 3
29 Antifungal Agents Phase 3
30 Cytochrome P-450 Enzyme Inhibitors Phase 3
31 Steroid Synthesis Inhibitors Phase 3
Hydroxyitraconazole Phase 3
33 Cytochrome P-450 CYP2C19 Inhibitors Phase 3
34 Liposomal amphotericin B Phase 3
35 Antiparasitic Agents Phase 3
36 Antiprotozoal Agents Phase 3
37 Emetics Phase 3
38 Antibiotics, Antitubercular Phase 3
39 Adjuvants, Immunologic Phase 3
40 Histamine H2 Antagonists Phase 3
41 Keratolytic Agents Phase 3
42 Dermatologic Agents Phase 3
43 Podophyllotoxin Phase 3 518-28-5
44 Tubulin Modulators Phase 3
45 Antimitotic Agents Phase 3
46 Antineoplastic Agents, Phytogenic Phase 3
47 Alkylating Agents Phase 3
48 Albumin-Bound Paclitaxel Phase 3
Isophosphamide mustard Phase 3 0
50 Antineoplastic Agents, Alkylating Phase 3

Interventional clinical trials:

(show top 50) (show all 60)
# Name Status NCT ID Phase Drugs
1 Randomized Phase II/III Study of Taxol/Paclitaxel-BEP Versus BEP in Patients With Intermediate Prognosis Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
2 A Risk-Adapted Strategy of the Use of Dose-Dense Chemotherapy in Patients With Poor-Prognosis Disseminated Non-Seminomatous Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
3 A Randomized Phase III Study of Sequential High-Dose Cisplatinum/Etoposide/Ifosfamide Plus Stem Cell Support Versus BEP in Patients With Poor Prognosis Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
4 A Randomized Double-Blind Placebo-Controlled Phase III Study To Evaluate The Safety And Efficacy Of Palivizumab Combined With Aerosolized Ribavirin Compared To Ribavirin Alone To Treat RSV Pneumonia In Patients With Bone Marrow Transplants (BMT) Completed NCT00014391 Phase 3 ribavirin
5 Phase III Study of Captopril in Patients Undergoing Autologous Bone Marrow/Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
6 A Randomized, Comparative Study of Itraconazole Versus Fluconazole for Prevention of Aspergillus Infections in Peripheral Blood Stem Cell and Marrow Transplant Recipients Completed NCT00003883 Phase 3 fluconazole;itraconazole
8 A Multicenter, Double-Blind, Randomized, Comparative Study To Evaluate The Safety, Tolerability, And Efficacy Of MK-0991 Versus (Amphotericin B) Liposome For Injection As Empirical Therapy In Patients With Persistent Fever And Neutropenia Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
9 A Strategic Study to Determine the Optimal Moment to Initiate Systemic Antifungal Therapy With Ambisome in Granulocytopenic Cancer Patients With Unexplained Fever Refractory to Empirical Antibacterials Completed NCT00003938 Phase 3 liposomal amphotericin B
10 A Phase III Study Of Reduced Therapy In The Treatment Of Children With Low And Intermediate Risk Extracranial Germ Cell Tumors Completed NCT00053352 Phase 3 cisplatin;etoposide
11 SIOP Intracranial Germ Cell Tumours Protocol Completed NCT00293358 Phase 3 carboplatin;cisplatin;etoposide phosphate;ifosfamide
12 Randomized Controlled Trial of Acupressure to Control Chemotherapy-Induced Nausea (CIN) in Children Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
13 A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel, Ifosfamide, and Cisplatin (TIP) With High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide Followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
14 A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide;Etoposide Phosphate
15 A Randomized Phase III Study of Paclitaxel, Ifosfamide and Cisplatin Versus Vinblastine, Ifosfamide and Cisplatin as Second-Line Therapy for Patients With Relapsed/Resistant Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
16 Phase I/II Multicentre Trial of Salvage Chemotherapy With Gem-TIP for Relapsed Germ Cell Cancer Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
17 A Phase II Study of BMS-247550 In Advanced Germ Cell Tumor Patients - THERAPEUTIC/DIAGNOSTIC PROTOCOL Completed NCT00070096 Phase 2 ixabepilone
18 A Phase II Study of Sunitinib in Patients With Refractory or Relapsed Germ Cell Tumors Completed NCT00453310 Phase 2 sunitinib malate
19 Accelerated BEP Chemotherapy for Intermediate and High Risk Metastatic Germ Cell Tumor Completed NCT00453232 Phase 2 cisplatin;etoposide
20 A Study of Paclitaxel, Cisplatin and Ifosfamide as Induction Therapy in the Treatment of Patients Relapsing After BEP Chemotherapy for Metastatic Germ Cell Tumors Completed NCT00004077 Phase 2 cisplatin;ifosfamide;paclitaxel
21 Phase II Trial of Paclitaxel, Ifosfamide, and Cisplatin in Previously Untreated Intermediate and Poor Risk Germ Cell Tumor Patients Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
22 Tandem High-Dose Chemotherapy With Autologous Stem Cell Rescue for Poor-Prognosis Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
23 Oral Beclomethasone Dipropionate Capsules for Treatment of Intestinal Graft-Versus-Host Disease: Compassionate Use in Patients With Contraindictions to High-Dose Immunosuppressive Therapy Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
24 Combination of Interleukin 11 (Neumega) With G-CSF to Mobilize Autologous Peripheral Blood Stem Cells (PBSC) Completed NCT00004157 Phase 2
25 Donor Lymphocyte Infusion (DLI) as Adoptive Immunotherapy for Relapse Malignancies After Allogeneic Hematopoietic Transplantation Completed NCT00003887 Phase 2
26 Cytokine-Based Immunotherapy Following High-Dose Chemotherapy and Autologous Stem Cell Transplantation Completed NCT00003408 Phase 2
28 Randomized Phase II Trial of Intensive Induction Chemotherapy (CBOP/BEP) and Standard BEP Chemotherapy in Poor Prognosis Male Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
29 Treatment of Recurrent or Resistant Pediatric Malignant Germ Cell Tumors With Paclitaxel, Ifosfamide and Carboplatin Completed NCT00467051 Phase 2 Carboplatin;Ifosfamide;Paclitaxel
30 Phase II Treatment of Children With Newly Diagnosed Malignant Central Nervous System Tumors With Temozolomide Prior to Radiation Therapy Completed NCT00005955 Phase 2 temozolomide
31 Phase II Pre-Irradiation Chemotherapy for Central Nervous System Germ Cell Malignancies Completed NCT00002472 Phase 2 cisplatin;etoposide
32 Phase II Study of Avelumab in Multiple Relapsed/Refractory Testicular Germ Cell Cancer. Completed NCT03403777 Phase 2 Avelumab
33 A Phase II Study To Assess The Ability Of Neoadjuvant Chemotherapy Plus/Minus Second Look Surgery To Eliminate All Measurable Disease Prior To Radiotherapy For NGGCT Completed NCT00047320 Phase 2 carboplatin;etoposide;ifosfamide;thiotepa
34 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
35 Anti-1-amino-3-18F-flurocyclobutane-1-carboxylic Acid (Axumin) Positron Emission Tomography/Computed Tomography Prior to Retroperitoneal Lymph Node Dissection for Testicular Cancer Recruiting NCT03426865 Phase 2 Axumin PET scan
36 Dasatinib With Ifosfamide, Carboplatin, Etoposide: A Pediatric Phase I/II Trial Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
37 A Phase I Trial of Recombinant Human Interleukin-12 After High-Dose Therapy and Autologous Hematopoietic Stem Cell Support Completed NCT00003107 Phase 1
38 A Phase I Study of Active Immunotherapy With Carcinoembryonic Antigen RNA-Pulsed, Autologous Human Cultured Dendritic Cells in Patients With Metastatic Malignancies Expressing Carcinoembryonic Antigen Completed NCT00004604 Phase 1
39 A Phase I Study of Pazopanib as a Single Agent for Children With Relapsed or Refractory Solid Tumors Completed NCT00929903 Phase 1 pazopanib hydrochloride
40 Phase I Study to Determine the Safety of MEN-10755 (BMS-195615) in Patients With a Solid Tumor on a Short I.V. Infusion Given Once Every Week for 3 Consecutive Weeks, Followed by One Week's Rest Completed NCT00003982 Phase 1 sabarubicin
41 A Multi-Center Phase Ib Study of Oxaliplatin (NSC #266046) in Combination With Fluorouracil and Leucovorin in Pediatric Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
42 A Phase I Study of Vorinostat and Bortezomib in Children With Refractory or Recurrent Solid Tumors, Including CNS Tumors and Lymphomas Completed NCT00994500 Phase 1 vorinostat;bortezomib
43 A Phase I Study of SAHA and Temozolomide in Children With Relapsed or Refractory Primary Brain or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
44 CTLA-4 Blockade With MDX-010 to Induce Graft-Versus-Malignancy Effects Following Allogeneic Hematopoietic Stem Cell Transplantation Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
45 A Phase I Study of Sunitinib (SU11248), an Oral Multi-Targeted Tyrosine Kinase Inhibitor, in Children With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
46 Phase I and Pharmacokinetic Trial of PTC299 in Pediatric Patients With Refractory or Recurrent CNS Tumors Completed NCT01158300 Phase 1 VEGF inhibitor PTC299
47 A Phase I Dose Escalation Study of a 2 Day Oral Lapatinib Chemosensitization Pulse Given Prior To Weekly Intravenous Abraxane™ in Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1 lapatinib;paclitaxel
48 A Phase 1 Study of Imetelstat, a Telomerase Inhibitor, in Children With Refractory or Recurrent Solid Tumors and Lymphomas Completed NCT01273090 Phase 1 imetelstat sodium
49 A Pilot Study of Intensive Chemotherapy With Peripheral Stem Cell Support for Infants With Malignant Brain Tumors Completed NCT00003141 Phase 1 carboplatin;cisplatin;cyclophosphamide;etoposide;thiotepa;vincristine sulfate
50 A PHASE 1/2 STUDY OF RO4929097, AN ORAL SMALL MOLECULE INHIBITOR OF GAMMA-SECRETASE, IN CHILDREN WITH RELAPSED/REFRACTORY SOLID OR CNS TUMORS, LYMPHOMA, OR T-CELL LEUKEMIA Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone

Search NIH Clinical Center for Testicular Yolk Sac Tumor

Genetic Tests for Testicular Yolk Sac Tumor

Anatomical Context for Testicular Yolk Sac Tumor

MalaCards organs/tissues related to Testicular Yolk Sac Tumor:

Testis, Ovary, Bone, Brain, Pineal, Liver, Bone Marrow

Publications for Testicular Yolk Sac Tumor

Articles related to Testicular Yolk Sac Tumor:

(show top 50) (show all 1288)
# Title Authors PMID Year
[Clinical analysis of stage I pediatric testicular yolk sac tumors: a report of ten cases]. 9 38
19000459 2008
Alpha-fetoprotein (AFP)-producing gastric carcinoma. Is it hepatoid differentiation? 9 38
1690592 1990
Management of Stage II Germ Cell Tumors: Be Sure, Be Patient, Be Safe. 38
31180818 2019
Wnt suppressor and stem cell regulator TCF7L1 is a sensitive immunohistochemical marker to differentiate testicular seminoma from non-seminomatous germ cell tumor. 38
31381875 2019
Endometrial tumors with yolk sac tumor-like morphologic patterns or immunophenotypes: an expanded appraisal. 38
31375771 2019
A case of malignant rhabdoid tumor mimicking yolk sac tumor. 38
31034722 2019
A primary third ventricle mixed germ cell tumor with leptomeningeal dissemination of immature teratoma component. 38
31418081 2019
Intraoperative Scrape Cytology from Ovarian Masss Lesions: A Study of 81 Cases. 38
31359919 2019
Albumin In Situ Hybridization Can Be Positive in Adenocarcinomas and Other Tumors From Diverse Sites. 38
31107526 2019
Presacral masses and sacrococcygeal teratomas in patients with and without anorectal malformations: A single institution comparative study. 38
30630596 2019
Hepatoid Carcinoma of the Ovary: Clinical, Histopathologic, and Immunophenotypic Features. 38
30628840 2019
Endoscopic Transnasal Resection of Suprasellar Teratoma. 38
30708386 2019
Effects of cognitive behavioral therapy on psychological adjustment in Chinese pediatric cancer patients receiving chemotherapy: A randomized trial. 38
31277176 2019
Pathogenesis of Testicular Germ Cell Neoplasia: A Conceptual Approach. 38
30950848 2019
Germ Cell Tumors of the Female Genital Tract. 38
31097117 2019
Prenatal Exposure to Air Toxics and Malignant Germ Cell Tumors in Young Children. 38
31045852 2019
Virilization in a Girl Caused by an Ovarian Yolk Sac Tumor: A Case Report. 38
30630034 2019
Gonadoblastoma-Associated Mixed Gonadal Germ Cell Tumor with Dysgerminoma and Hepatoid Yolk Sac Tumor Components in 46XY Gonadal Dysgenesis. 38
31175959 2019
TCam-2 Cells Deficient for SOX2 and FOXA2 Are Blocked in Differentiation and Maintain a Seminoma-Like Cell Fate In Vivo. 38
31130628 2019
Expression of cellular apoptosis susceptibility (CAS) in the human testis and testicular germ cell tumors. 38
31140031 2019
Clinicopathologic Features and Chromosome 12p Status of Pediatric Sacrococcygeal Teratomas: A Multi-institutional Analysis. 38
30176765 2019
Late and Rapid Relapse in Mediastinum from Testicular Germ Cell Tumor Stage I Over 13 Years after Surgery. 38
31320874 2019
An up-date on novel molecular targets in testicular germ cell tumors subtypes. 38
31218171 2019
FDG PET/CT Evaluation of Pediatric Patients With Yolk Sac Tumor. 38
31120780 2019
Extragonadal Yolk Sac Tumor Limited to the Myometrium: Report of a Case With Potential Fertility Preservation and Molecular Analysis Suggesting Germ Cell Origin. 38
31033797 2019
[Testicular germ cell tumors: Histopathological and molecular features]. 38
30905378 2019
Primary yolk sac tumor originating from the endometrium: A case report and literature review. 38
30985686 2019
Poor prognosis of retroperitoneal mixed extragonadal germ cell tumors in an HIV-infected man with severe immunosuppression and bilateral cryptorchidism: a case report. 38
30885154 2019
Recent advances in the regulation of testicular germ cell tumors by microRNAs. 38
30844711 2019
A case of ovarian endometrioid adenocarcinoma with yolk sac differentiation and Lynch syndrome. 38
30723761 2019
Cytokeratin 7, inhibin, and p63 in testicular germ cell tumor: superior markers of choriocarcinoma compared to β-human chorionic gonadotropin. 38
30359635 2019
Successful yolk-sac tumor treatment with fertility-sparing partial oophorectomy. 38
30581951 2019
Extragonadal yolk sac tumor following congenital buccal mature cystic teratoma. 38
30967724 2019
A retrospective analysis of the pattern of care and survival in patients with malignant ovarian germ cell tumors. 38
30766850 2019
Yolk Sac Tumor in an Eight-Year-Old Girl: A Case Report and Literature Review. 38
31114774 2019
Postchemotherapy sarcoma as a somatic-type malignancy derived from the gonadal yolk sac tumor in a patient with 46, XY pure gonadal dysgenesis. 38
30992672 2019
Next-Generation Cancer Immunotherapy Targeting Glypican-3. 38
31024850 2019
Experience of applying cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian teratoma with malignant transformation and peritoneal dissemination. 38
30679911 2019
First Case of Mature Teratoma and Yolk Sac Testis Tumor Associated to Inherited MEN-1 Syndrome. 38
31249555 2019
New Anti-Cancer Strategies in Testicular Germ Cell Tumors. 38
30636617 2019
Are omentectomy and lymphadenectomy necessary in patients with apparently early-stage malignant ovarian germ cell tumors? 38
30674572 2019
Recurrent ovarian mixed germ cell tumor with unusual malignant transformation: a case report. 38
30630520 2019
Rapidly growing juvenile granulosa cell tumor of the ovary arising in adult: a case report and review of the literature. 38
30547828 2018
Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists. 38
30041024 2018
Is fertility sparing surgery a treatment option for young patients with yolk sac tumor? 38
30465413 2018
Prepubertal testicular tumors in China: a 10-year experience with 67 cases. 38
30324570 2018
Central Nervous System-type Neuroepithelial Tumors and Tumor-like Proliferations Developing in the Gynecologic Tract and Pelvis: Clinicopathologic Analysis of 23 Cases. 38
30074494 2018
Role of HNF1β in the differential diagnosis of yolk sac tumor from other germ cell tumors. 38
29753846 2018
Multidisciplinary team for the diagnosis and treatment of 2 cases of primary intestinal yolk sac tumor. 38
30766756 2018
Yolk Sac Tumor of Stomach: Case Report and Review of Literature. 38
30443123 2018

Variations for Testicular Yolk Sac Tumor

Expression for Testicular Yolk Sac Tumor

Search GEO for disease gene expression data for Testicular Yolk Sac Tumor.

Pathways for Testicular Yolk Sac Tumor

Pathways related to Testicular Yolk Sac Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.22 RUNX3 AFP
2 10.83 TF RUNX3

GO Terms for Testicular Yolk Sac Tumor

Cellular components related to Testicular Yolk Sac Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.62 TF HP AHSG AFP
2 extracellular space GO:0005615 9.46 TF HP AHSG AFP
3 secretory granule lumen GO:0034774 9.26 TF AHSG
4 endoplasmic reticulum lumen GO:0005788 9.13 TF AHSG AFP
5 blood microparticle GO:0072562 8.8 TF HP AHSG

Biological processes related to Testicular Yolk Sac Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.33 TF AHSG AFP
2 platelet degranulation GO:0002576 9.26 TF AHSG
3 acute-phase response GO:0006953 8.96 HP AHSG
4 cellular protein metabolic process GO:0044267 8.8 TF AHSG AFP

Sources for Testicular Yolk Sac Tumor

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
32 HPO
33 ICD10
34 ICD10 via Orphanet
38 LifeMap
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
55 Novoseek
58 OMIM via Orphanet
62 PubMed
71 Tocris
73 UMLS via Orphanet
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