NNT
MCID: TTN001
MIFTS: 33

Tetanus Neonatorum (NNT)

Categories: Infectious diseases

Aliases & Classifications for Tetanus Neonatorum

MalaCards integrated aliases for Tetanus Neonatorum:

Name: Tetanus Neonatorum 12 15 73
Neonatal Tetanus 12
Nnt 48

Classifications:



External Ids:

Disease Ontology 12 DOID:13521
ICD10 33 A33
ICD9CM 35 771.3
NCIt 50 C116814
SNOMED-CT 68 43424001
UMLS 73 C0343312

Summaries for Tetanus Neonatorum

Disease Ontology : 12 A tetanus that occurs in newborn babies when the birth cord stump gets dirty through cutting it with an unclean blade or applying substances containing bacteria to it. The infection has symptom stiff body, has symptom muscle spasms, has symptom difficulty in breathing, and has symptom exhaustion.

MalaCards based summary : Tetanus Neonatorum, also known as neonatal tetanus, is related to familial glucocorticoid deficiency and crisponi/cold-induced sweating syndrome 1. An important gene associated with Tetanus Neonatorum is DPT (Dermatopontin), and among its related pathways/superpathways is Peptide hormone metabolism. Affiliated tissues include pituitary, testes and skin.

Related Diseases for Tetanus Neonatorum

Graphical network of the top 20 diseases related to Tetanus Neonatorum:



Diseases related to Tetanus Neonatorum

Symptoms & Phenotypes for Tetanus Neonatorum

Drugs & Therapeutics for Tetanus Neonatorum

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Maternal Immunization With MenAfriVacâ„¢ Recruiting NCT03746665 Phase 3

Search NIH Clinical Center for Tetanus Neonatorum

Genetic Tests for Tetanus Neonatorum

Anatomical Context for Tetanus Neonatorum

MalaCards organs/tissues related to Tetanus Neonatorum:

41
Pituitary, Testes, Skin, Brain

Publications for Tetanus Neonatorum

Articles related to Tetanus Neonatorum:

(show top 50) (show all 434)
# Title Authors Year
1
Achieving neonatal tetanus elimination in Nigeria: undisclosed challenges and prospects. ( 28147895 )
2018
2
Post-neonatal Tetanus in a PICU of a Developing Economy: Intensive Care Needs, Outcome and Predictors of Mortality. ( 28460120 )
2018
3
Neonatal tetanus in an African newborn. ( 29146512 )
2018
4
Maternal and neonatal tetanus elimination: validation in Punjab Province, Pakistan, November 2016. ( 28116893 )
2017
5
Elimination of Maternal and Neonatal Tetanus in India: A Triumph Tale. ( 28348725 )
2017
6
Eliminating maternal and neonatal tetanus and closing the immunity gap. ( 28402808 )
2017
7
Validation of maternal and neonatal tetanus elimination in Equatorial Guinea, 2016. ( 28622465 )
2017
8
Neonatal Tetanus: Still a Scourge after Elimination from India. ( 27771660 )
2016
9
Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies. ( 26904135 )
2016
10
Serological Monitoring Is Key To Sustain Progress of the Maternal and Neonatal Tetanus Elimination Initiative. ( 27226278 )
2016
11
Maternal and neonatal tetanus validation assessment in Region 4, Indonesia, May 2016. ( 27348870 )
2016
12
Maternal and neonatal tetanus. ( 25149223 )
2015
13
Prognosis of neonatal tetanus in the modern management era: an observational study in 107 Vietnamese infants. ( 25499039 )
2015
14
Maternal and neonatal tetanus elimination: from protecting women and newborns to protecting all. ( 25678822 )
2015
15
Incidence and risk factors for neonatal tetanus in admissions to Kilifi County Hospital, Kenya. ( 25849440 )
2015
16
India is declared free of maternal and neonatal tetanus. ( 26032894 )
2015
17
India is declared free of maternal and neonatal tetanus. ( 26047966 )
2015
18
Vaccines for women for preventing neonatal tetanus. ( 26144877 )
2015
19
RISK CHARACTERIZATION OF MATERNAL AND NEONATAL TETANUS IN VIEW OF TETANUS VACCINATION CAMPAIGNS IN PAKISTAN. ( 26182781 )
2015
20
Risk factors of neonatal tetanus in Wenzhou, China: a case-control study. ( 26668764 )
2015
21
Maternal and neonatal tetanus elimination: validation survey in 4 States in India, April 2013. ( 24864342 )
2014
22
Interventions to reduce neonatal mortality from neonatal tetanus in low and middle income countries--a systematic review. ( 23570611 )
2013
23
A review of neonatal tetanus in University of Maiduguri Teaching Hospital, North-eastern Nigeria. ( 24665154 )
2013
24
HE BURDEN AND CHALLENGES OF NEONATAL TETANUS IN KILIFI DISTRICT, KENYA--2004-7. ( 26866113 )
2013
25
Elimination of maternal and neonatal tetanus in Senegal. ( 22905366 )
2012
26
Clostridium tetani infections in newborn infants: a tetanus neonatorum review. ( 23949463 )
2011
27
Completeness of reporting and case ascertainment for neonatal tetanus in rural Pakistan. ( 21683637 )
2011
28
Validation of elimination: maternal and neonatal tetanus in Mozambique, 2010. ( 22046597 )
2011
29
Validation of elimination of neonatal tetanus in Turkey by lot quality assurance cluster sampling. ( 19391312 )
2009
30
Process of neonatal tetanus elimination in Nepal. ( 19443437 )
2009
31
Scaling up interventions to eliminate neonatal tetanus: factors associated with the coverage of tetanus toxoid and clean deliveries among women in Vientiane, Lao PDR. ( 19450637 )
2009
32
Neonatal tetanus in the babies of Nigerian mothers immunised against Tetanus. ( 19535745 )
2009
33
Status of neonatal tetanus elimination in the United Republic of Tanzania - results from a lot quality-assurance cluster survey. ( 19630189 )
2009
34
Neonatal tetanus in Malaysia. ( 19852312 )
2009
35
Neonatal tetanus: a study of five cases in Sandakan, Sabah. ( 19852330 )
2009
36
Validation of neonatal tetanus elimination in the Congo by a lot quality-assurance cluster sample survey. ( 19899227 )
2009
37
Neonatal tetanus. ( 18242410 )
2008
38
Validation of neonatal tetanus elimination in Zambia by lot quality-assurance cluster sampling. ( 18389557 )
2008
39
Validation of neonatal tetanus elimination in selected states--India, 2007. ( 18499929 )
2008
40
Neonatal tetanus in Turkey; what has changed in the last decade? ( 18713452 )
2008
41
Validation of neonatal tetanus elimination in Bangladesh by lot quality-assurance cluster sampling. ( 18720575 )
2008
42
St Kilda, the neonatal tetanus tragedy of the nineteenth century and some twenty-first century answers. ( 19069042 )
2008
43
Pediatric and neonatal tetanus: a hospital based study at eastern Nepal. ( 19253861 )
2008
44
Neonatal tetanus in Nigeria: does it still pose a major threat to neonatal survival? ( 17185443 )
2007
45
Validation of neonatal tetanus elimination in India using lot quality-assurance cluster sampling. ( 17465075 )
2007
46
Validation of neonatal tetanus elimination in Egypt by lot quality-assurance cluster sampling. ( 17600956 )
2007
47
The effects of maternal malaria and HIV-1 infection on the effort to eliminate neonatal tetanus. ( 17624833 )
2007
48
Neonatal tetanus at the close of the 20th century in Nigeria. ( 17716507 )
2007
49
Validation of neonatal tetanus elimination in Mali by lot quality-assurance cluster sampling. ( 17763564 )
2007
50
Maternal and neonatal tetanus. ( 17854885 )
2007

Variations for Tetanus Neonatorum

Expression for Tetanus Neonatorum

Search GEO for disease gene expression data for Tetanus Neonatorum.

Pathways for Tetanus Neonatorum

Pathways related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.88 ACE2 CPN1

GO Terms for Tetanus Neonatorum

Cellular components related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 ACE2 CPN1 DPT TNC

Biological processes related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 9.26 ACE2 TNC
2 response to ethanol GO:0045471 9.16 OPRM1 TNC
3 wound healing GO:0042060 8.96 OPRM1 TNC
4 locomotory behavior GO:0007626 8.62 OPRM1 SLC18A2

Molecular functions related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metallopeptidase activity GO:0008237 9.16 ACE2 CPN1
2 extracellular matrix structural constituent GO:0005201 8.96 DPT TNC
3 metallocarboxypeptidase activity GO:0004181 8.62 ACE2 CPN1

Sources for Tetanus Neonatorum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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