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NNT
MCID: TTN001
MIFTS: 29

Tetanus Neonatorum (NNT)

Categories: Infectious diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Tetanus Neonatorum

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MalaCards integrated aliases for Tetanus Neonatorum:

Name: Tetanus Neonatorum 12 15 71 32
Neonatal Tetanus 12
Nnt 47

Classifications:

MalaCards categories:
Global: Infectious diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:13521
ICD9CM 34 771.3
NCIt 49 C116814
SNOMED-CT 67 43424001
ICD10 32 A33
UMLS 71 C0343312
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Summaries for Tetanus Neonatorum

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Disease Ontology : 12 A tetanus that occurs in newborn babies when the birth cord stump gets dirty through cutting it with an unclean blade or applying substances containing bacteria to it. The infection has symptom stiff body, has symptom muscle spasms, has symptom difficulty in breathing, and has symptom exhaustion.

MalaCards based summary : Tetanus Neonatorum, also known as neonatal tetanus, is related to yaws and familial glucocorticoid deficiency. An important gene associated with Tetanus Neonatorum is MNT (MAX Network Transcriptional Repressor). The drugs mometasone furoate and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and brain.

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Related Diseases for Tetanus Neonatorum

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Diseases related to Tetanus Neonatorum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)
# Related Disease Score Top Affiliating Genes
1 yaws 29.5 MPG ADIRF
2 familial glucocorticoid deficiency 12.1
3 glucocorticoid deficiency 4 with or without mineralocorticoid deficiency 11.9
4 glucose intolerance 11.6
5 left ventricular noncompaction 11.6
6 tetanus 11.6
7 achalasia-addisonianism-alacrima syndrome 11.1
8 microcephaly 1, primary, autosomal recessive 11.1
9 adrenal insufficiency, congenital, with 46,xy sex reversal, partial or complete 11.1
10 seckel syndrome 5 11.1
11 intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 11.1
12 cortisone reductase deficiency 11.1
13 testicular leydig cell tumor 11.1
14 poliomyelitis 10.2
15 diphtheria 10.2
16 otitis media 10.1
17 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
18 pertussis 10.1
19 measles 10.1
20 maple syrup urine disease 10.1
21 aspiration pneumonia 10.1
22 bronchopneumonia 10.1
23 quadriplegia 10.1
24 kwashiorkor 10.1
25 alzheimer disease 10.0
26 spondyloarthropathy 1 10.0
27 parkinson disease, late-onset 10.0
28 scleroderma, familial progressive 10.0
29 cryptorchidism, unilateral or bilateral 10.0
30 diamond-blackfan anemia 2 10.0
31 pulmonary disease, chronic obstructive 10.0
32 congenital hypothyroidism 10.0
33 pain agnosia 10.0
34 inflammatory spondylopathy 10.0
35 varicocele 10.0
36 azoospermia 10.0
37 hypothyroidism 10.0
38 endometriosis 10.0
39 anovulation 10.0
40 infertility 10.0
41 eye disease 10.0
42 spondylitis 10.0
43 hypertrophic cardiomyopathy 10.0
44 mitochondrial disorders 10.0
45 nr0b1-related adrenal hypoplasia congenita 10.0
46 precocious puberty 10.0
47 raynaud phenomenon 10.0
48 primary adrenal insufficiency 10.0
49 hypercarotenemia and vitamin a deficiency, autosomal dominant 10.0
50 cyanosis, transient neonatal 10.0

Graphical network of the top 20 diseases related to Tetanus Neonatorum:



Diseases related to Tetanus Neonatorum
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Symptoms & Phenotypes for Tetanus Neonatorum

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Drugs & Therapeutics for Tetanus Neonatorum

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Drugs for Tetanus Neonatorum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
mometasone furoate Approved, Investigational, Vet_approved Phase 3 83919-23-7
2 Vaccines Phase 3
3 Lactoferrin Phase 3
4 Anti-Infective Agents Phase 3
5 Immunologic Factors Phase 3
6 Antitoxins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Can Bovine Lactoferrin Prevent Neonatal Infections in Low Birth Weight Babies in Karachi, Sindh, Pakistan. Recruiting NCT03431558 Phase 3 Glucon-D 99.4% (Placebo)
2 Maternal Immunization With MenAfriVac™ Recruiting NCT03746665 Phase 3
3 Multicenter Study of Tetanus Patients in Fujian Province of China Completed NCT04165928
4 Development and Evaluation of Perinatal Handwashing Promotion for Improved Maternal Handwashing Behavior Completed NCT01309321

Search NIH Clinical Center for Tetanus Neonatorum

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Genetic Tests for Tetanus Neonatorum

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Anatomical Context for Tetanus Neonatorum

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MalaCards organs/tissues related to Tetanus Neonatorum:

40
Testes, Skin, Brain, Eye
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Publications for Tetanus Neonatorum

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Articles related to Tetanus Neonatorum:

(show top 50) (show all 853)
# Title Authors PMID Year
1
Neonatal tetanus in eastern Uganda: improved outcome following the implementation of a neonatal tetanus protocol. 61
31474192 2020
2
An investment case for maternal and neonatal tetanus elimination. 61
31980197 2020
3
Demography and Symptom Profile of Tetanus: A Cross-sectional Observation in an Infectious Disease Hospital of Bangladesh. 61
31915348 2020
4
Seroprevalence of anti-tetanus antibodies in mothers and cord blood and associated factors in health-care settings in Lao People's Democratic Republic. 61
31735506 2020
5
New immunization strategies: adapting to global challenges. 61
31802153 2020
6
Effectiveness of birthing kits for clean childbirth: a systematic review. 61
31340003 2020
7
Collective memory of umbilical cord stump care: an educational experience. 61
31851274 2019
8
[Specifications for diagnosis and treatment of non-neonatal tetanus]. 61
31795576 2019
9
[Improving immunization strategy and promoting the development of tetanus prevention and control in China]. 61
31795575 2019
10
[Guidelines for the use of post-traumatic tetanus vaccines and passive immune preparation]. 61
31795577 2019
11
Effect of cash incentives on tetanus toxoid vaccination among rural Nigerian women: a randomized controlled trial. 61
31567041 2019
12
The CORE Group Polio Project's Community Volunteers and Polio Eradication in Ethiopia: Self-Reports of Their Activities, Knowledge, and Contributions. 61
31760977 2019
13
Use of Social Mobilization and Community Mobilizers by Non-governmental Health Organizations in Malawi to Support the Eradication of Polio, Improve Routine Immunization Coverage, and Control Measles and Neonatal Tetanus. 61
31760969 2019
14
Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital. 61
31488984 2019
15
The Prevalence and Case-Fatality Rates of Post-Neonatal Tetanus in a Population of Hospitalized Nigerian Children: An 8-Year Retrospective Review. 61
31397484 2019
16
Knowledge about and preventive practices against neonatal tetanus among young Nigerian women. 61
31258290 2019
17
Maternal Immunization and Antenatal Care Situation Analysis (MIACSA) study protocol: a multiregional, cross-sectional analysis of maternal immunization delivery strategies to reduce maternal and neonatal morbidity and mortality. 61
31167857 2019
18
SERUM TOTAL IgG AND TETANUS SPECIFIC IgG IN NIGERIAN HUMAN IMMUNODEFICIENCY VIRUS INFECTED PRIMIGRAVIDAE AND THE CORD BLOOD OF THEIR BABIES AT BIRTH. 61
31768150 2019
19
Immunization in Vietnam. 61
31069373 2019
20
Maternal immunization: A call to accelerate progress. 61
31014962 2019
21
Key considerations for successful implementation of maternal immunization programs in low and middle income countries. 61
30676250 2019
22
Tetanus in Poland in 2017 61
31385677 2019
23
Eliminating Maternal and Neonatal Tetanus and Promoting Clean Delivery Practices Through Disposable Clean Birth Kits. 61
31824909 2019
24
A Rare Case of Localized Tetanus. 61
30294137 2018
25
Effects of a community-based data for decision-making intervention on maternal and newborn health care practices in Ethiopia: a dose-response study. 61
30255793 2018
26
Pre-post effects of a tetanus care protocol implementation in a sub-Saharan African intensive care unit. 61
30161119 2018
27
Functional and proteomic comparison of different techniques to produce equine anti-tetanus immunoglobulin F(ab')2 fragments. 61
29883887 2018
28
The crucial role of maternal care providers as vaccinators for pregnant women. 61
28822646 2018
29
Maternal and Neonatal Tetanus Elimination (MNTE) in The WHO African Region. 61
30882092 2018
30
Determinants and perceptions of the utilization of tetanus toxoid immunization among reproductive-age women in Dukem Town, Eastern Ethiopia: a community-based cross-sectional study. 61
29950171 2018
31
The role of timely initiation of antenatal care on protective dose tetanus toxoid immunization: the case of northern Ethiopia post natal mothers. 61
29907139 2018
32
Generalized tetanus in adults without antitetanus booster vaccination in southern Mauritania. 61
29744067 2018
33
Clinical features and outcomes of tetanus: Analysis using a National Inpatient Database in Japan. 61
29304489 2018
34
Post-neonatal Tetanus in a PICU of a Developing Economy: Intensive Care Needs, Outcome and Predictors of Mortality. 61
28460120 2018
35
Neonatal tetanus in an African newborn. 61
29146512 2018
36
[Response capacity and challenges of the Cuban health system against communicable diseasesCapacidade de resposta e desafios do sistema de saúde cubano contra doenças transmissíveis]. 61
31093059 2018
37
Maternal immunisation: What have been the gains? Where are the gaps? What does the future hold? 61
30443339 2018
38
A Pilot Study: Factors Influencing Compliance With Tetanus-Diphtheria Vaccine in Katsina State, Northwestern Nigeria. 61
30083576 2018
39
Achieving neonatal tetanus elimination in Nigeria: undisclosed challenges and prospects. 61
28147895 2018
40
Exploring the spatial heterogeneity in different doses of vaccination coverage in India. 61
30485291 2018
41
Tetanus Toxoid Immunization Status and Associated Factors among Mothers in Damboya Woreda, Kembata Tembaro Zone, SNNP, Ethiopia. 61
30595915 2018
42
Tetanus in adult males, Bugando Medical Centre, United Republic of Tanzania. 61
29147059 2017
43
Changes in cause-specific neonatal and 1-59-month child mortality in India from 2000 to 2015: a nationally representative survey. 61
28939096 2017
44
Expansion of Vaccination Services and Strengthening Vaccine-Preventable Diseases Surveillance in Haiti, 2010-2016. 61
29064356 2017
45
Clinical Profile and Outcome of Pediatrics Tetanus: The Experience of a Tertiary Hospital in Ethiopia. 61
29217961 2017
46
Long-term outcome in survivors of neonatal tetanus following specialist intensive care in Vietnam. 61
28946862 2017
47
Knowledge, attitudes and practices related to tetanus toxoid vaccination in women of childbearing age: A cross-sectional study in peri-urban settlements of Karachi, Pakistan. 61
29317900 2017
48
Validation of maternal and neonatal tetanus elimination in Equatorial Guinea, 2016. 61
28622465 2017
49
Epidemiological and clinical aspects of neonatal tetanus from a tertiary care hospital. 61
30805505 2017
50
Nursing a critically ill tetanus patient in an intensive care unit in Zambia. 61
28493767 2017
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Variations for Tetanus Neonatorum

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Expression for Tetanus Neonatorum

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Search GEO for disease gene expression data for Tetanus Neonatorum.
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Pathways for Tetanus Neonatorum

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GO Terms for Tetanus Neonatorum

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Biological processes related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to radiation GO:0071478 8.62 NSMCE3 ADIRF
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Sources for Tetanus Neonatorum

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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