NNT
MCID: TTN001
MIFTS: 32

Tetanus Neonatorum (NNT)

Categories: Infectious diseases

Aliases & Classifications for Tetanus Neonatorum

MalaCards integrated aliases for Tetanus Neonatorum:

Name: Tetanus Neonatorum 12 15 74
Neonatal Tetanus 12
Nnt 49

Classifications:



External Ids:

Disease Ontology 12 DOID:13521
ICD9CM 36 771.3
NCIt 51 C116814
SNOMED-CT 69 43424001
ICD10 34 A33
UMLS 74 C0343312

Summaries for Tetanus Neonatorum

Disease Ontology : 12 A tetanus that occurs in newborn babies when the birth cord stump gets dirty through cutting it with an unclean blade or applying substances containing bacteria to it. The infection has symptom stiff body, has symptom muscle spasms, has symptom difficulty in breathing, and has symptom exhaustion.

MalaCards based summary : Tetanus Neonatorum, also known as neonatal tetanus, is related to familial glucocorticoid deficiency and left ventricular noncompaction. An important gene associated with Tetanus Neonatorum is DPT (Dermatopontin). The drugs mometasone furoate and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and brain, and related phenotype is behavior/neurological.

Related Diseases for Tetanus Neonatorum

Diseases related to Tetanus Neonatorum via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 familial glucocorticoid deficiency 12.0
2 left ventricular noncompaction 11.5
3 tetanus 11.5
4 glucocorticoid deficiency 4 with or without mineralocorticoid deficiency 11.4
5 adrenal insufficiency, congenital, with 46,xy sex reversal, partial or complete 11.2
6 intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 11.2
7 adrenal rest tumor 11.2
8 stomach carcinoma in situ 10.2 CRLF1 GLS2
9 hematocele of tunica vaginalis testis 10.2 AFP CRLF1
10 poliomyelitis 10.1
11 brachial plexus neuritis 10.1 DPT KANTR
12 salpingitis isthmica nodosa 10.1 AVPR2 KANTR
13 maple syrup urine disease 10.0
14 spondyloarthropathy 1 10.0
15 radin blood group antigen 10.0
16 horns in sheep 10.0
17 spondylitis 10.0
18 cytomegalic congenital adrenal hypoplasia 10.0
19 trigeminal nerve neoplasm 10.0 CRLF1 KANTR
20 neurilemmoma of the fifth cranial nerve 10.0 CRLF1 KANTR
21 paraphimosis 10.0 KANTR NUDT1
22 glossopharyngeal neuralgia 10.0 CRLF1 KANTR
23 oculomotor nerve paralysis 10.0 AFP KANTR
24 third cranial nerve disease 9.9 AFP KANTR
25 cold-induced sweating syndrome 9.9 CNTF CRLF1 KANTR
26 chronic salpingitis 9.9 AVPR2 KANTR
27 crisponi/cold-induced sweating syndrome 1 9.8
28 malaria 9.8
29 autosomal recessive disease 9.8
30 yaws 9.8
31 diphtheria 9.8
32 human immunodeficiency virus infectious disease 9.8
33 measles 9.8
34 cloacal exstrophy 9.8 AFP KANTR
35 transient global amnesia 9.8 CRLF1 KANTR

Graphical network of the top 20 diseases related to Tetanus Neonatorum:



Diseases related to Tetanus Neonatorum

Symptoms & Phenotypes for Tetanus Neonatorum

MGI Mouse Phenotypes related to Tetanus Neonatorum:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.23 AFP AVPR2 CNTF CRLF1 MNT NUDT1

Drugs & Therapeutics for Tetanus Neonatorum

Drugs for Tetanus Neonatorum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
mometasone furoate Approved, Investigational, Vet_approved Phase 3 83919-23-7
2 Vaccines Phase 3
3 Immunologic Factors Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Maternal Immunization With MenAfriVacâ„¢ Recruiting NCT03746665 Phase 3

Search NIH Clinical Center for Tetanus Neonatorum

Genetic Tests for Tetanus Neonatorum

Anatomical Context for Tetanus Neonatorum

MalaCards organs/tissues related to Tetanus Neonatorum:

42
Testes, Skin, Brain

Publications for Tetanus Neonatorum

Articles related to Tetanus Neonatorum:

(show top 50) (show all 432)
# Title Authors Year
1
Maternal and Neonatal Tetanus Elimination (MNTE) in The WHO African Region. ( 30882092 )
2018
2
Achieving neonatal tetanus elimination in Nigeria: undisclosed challenges and prospects. ( 28147895 )
2018
3
Post-neonatal Tetanus in a PICU of a Developing Economy: Intensive Care Needs, Outcome and Predictors of Mortality. ( 28460120 )
2018
4
Neonatal tetanus in an African newborn. ( 29146512 )
2018
5
Maternal and neonatal tetanus elimination: validation in Punjab Province, Pakistan, November 2016. ( 28116893 )
2017
6
Elimination of Maternal and Neonatal Tetanus in India: A Triumph Tale. ( 28348725 )
2017
7
Eliminating maternal and neonatal tetanus and closing the immunity gap. ( 28402808 )
2017
8
Validation of maternal and neonatal tetanus elimination in Equatorial Guinea, 2016. ( 28622465 )
2017
9
Epidemiological and clinical aspects of neonatal tetanus from a tertiary care hospital. ( 30805505 )
2017
10
Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies. ( 26904135 )
2016
11
Serological Monitoring Is Key To Sustain Progress of the Maternal and Neonatal Tetanus Elimination Initiative. ( 27226278 )
2016
12
Maternal and neonatal tetanus validation assessment in Region 4, Indonesia, May 2016. ( 27348870 )
2016
13
Neonatal Tetanus: Still a Scourge after Elimination from India. ( 27771660 )
2016
14
Maternal and neonatal tetanus. ( 25149223 )
2015
15
Prognosis of neonatal tetanus in the modern management era: an observational study in 107 Vietnamese infants. ( 25499039 )
2015
16
Maternal and neonatal tetanus elimination: from protecting women and newborns to protecting all. ( 25678822 )
2015
17
India is declared free of maternal and neonatal tetanus. ( 26032894 )
2015
18
India is declared free of maternal and neonatal tetanus. ( 26047966 )
2015
19
Vaccines for women for preventing neonatal tetanus. ( 26144877 )
2015
20
RISK CHARACTERIZATION OF MATERNAL AND NEONATAL TETANUS IN VIEW OF TETANUS VACCINATION CAMPAIGNS IN PAKISTAN. ( 26182781 )
2015
21
Risk factors of neonatal tetanus in Wenzhou, China: a case-control study. ( 26668764 )
2015
22
Maternal and neonatal tetanus elimination: validation survey in 4 States in India, April 2013. ( 24864342 )
2014
23
A review of neonatal tetanus in University of Maiduguri Teaching Hospital, North-eastern Nigeria. ( 24665154 )
2013
24
HE BURDEN AND CHALLENGES OF NEONATAL TETANUS IN KILIFI DISTRICT, KENYA--2004-7. ( 26866113 )
2013
25
Elimination of maternal and neonatal tetanus in Senegal. ( 22905366 )
2012
26
Clostridium tetani infections in newborn infants: a tetanus neonatorum review. ( 23949463 )
2011
27
Validation of elimination of neonatal tetanus in Turkey by lot quality assurance cluster sampling. ( 19391312 )
2009
28
Process of neonatal tetanus elimination in Nepal. ( 19443437 )
2009
29
Scaling up interventions to eliminate neonatal tetanus: factors associated with the coverage of tetanus toxoid and clean deliveries among women in Vientiane, Lao PDR. ( 19450637 )
2009
30
Neonatal tetanus in the babies of Nigerian mothers immunised against Tetanus. ( 19535745 )
2009
31
Status of neonatal tetanus elimination in the United Republic of Tanzania - results from a lot quality-assurance cluster survey. ( 19630189 )
2009
32
Neonatal tetanus in Malaysia. ( 19852312 )
2009
33
Neonatal tetanus: a study of five cases in Sandakan, Sabah. ( 19852330 )
2009
34
Validation of neonatal tetanus elimination in the Congo by a lot quality-assurance cluster sample survey. ( 19899227 )
2009
35
St Kilda, the neonatal tetanus tragedy of the nineteenth century and some twenty-first century answers. ( 19069042 )
2008
36
Pediatric and neonatal tetanus: a hospital based study at eastern Nepal. ( 19253861 )
2008
37
Neonatal tetanus. ( 18242410 )
2008
38
Validation of neonatal tetanus elimination in Zambia by lot quality-assurance cluster sampling. ( 18389557 )
2008
39
Validation of neonatal tetanus elimination in selected states--India, 2007. ( 18499929 )
2008
40
Neonatal tetanus in Turkey; what has changed in the last decade? ( 18713452 )
2008
41
Validation of neonatal tetanus elimination in Bangladesh by lot quality-assurance cluster sampling. ( 18720575 )
2008
42
Validation of neonatal tetanus elimination in India using lot quality-assurance cluster sampling. ( 17465075 )
2007
43
Validation of neonatal tetanus elimination in Egypt by lot quality-assurance cluster sampling. ( 17600956 )
2007
44
The effects of maternal malaria and HIV-1 infection on the effort to eliminate neonatal tetanus. ( 17624833 )
2007
45
Neonatal tetanus at the close of the 20th century in Nigeria. ( 17716507 )
2007
46
Validation of neonatal tetanus elimination in Mali by lot quality-assurance cluster sampling. ( 17763564 )
2007
47
Maternal and neonatal tetanus. ( 17854885 )
2007
48
Neonatal tetanus in Nigeria: does it still pose a major threat to neonatal survival? ( 17185443 )
2007
49
Viet Nam eliminates maternal and neonatal tetanus. ( 16622974 )
2006
50
Risk factors for neonatal tetanus--Busoga region, Uganda, 2002-2003. ( 16645579 )
2006

Variations for Tetanus Neonatorum

Expression for Tetanus Neonatorum

Search GEO for disease gene expression data for Tetanus Neonatorum.

Pathways for Tetanus Neonatorum

GO Terms for Tetanus Neonatorum

Cellular components related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.17 ACE2 AFP APELA CNTF CRLF1 DPT

Molecular functions related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ciliary neurotrophic factor receptor binding GO:0005127 8.62 CNTF CRLF1

Sources for Tetanus Neonatorum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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