NNT
MCID: TTN001
MIFTS: 32

Tetanus Neonatorum (NNT)

Categories: Infectious diseases

Aliases & Classifications for Tetanus Neonatorum

MalaCards integrated aliases for Tetanus Neonatorum:

Name: Tetanus Neonatorum 12 15 74
Neonatal Tetanus 12
Nnt 49

Classifications:



External Ids:

Disease Ontology 12 DOID:13521
ICD9CM 36 771.3
NCIt 51 C116814
SNOMED-CT 69 43424001
ICD10 34 A33
UMLS 74 C0343312

Summaries for Tetanus Neonatorum

Disease Ontology : 12 A tetanus that occurs in newborn babies when the birth cord stump gets dirty through cutting it with an unclean blade or applying substances containing bacteria to it. The infection has symptom stiff body, has symptom muscle spasms, has symptom difficulty in breathing, and has symptom exhaustion.

MalaCards based summary : Tetanus Neonatorum, also known as neonatal tetanus, is related to cold-induced sweating syndrome and familial glucocorticoid deficiency. An important gene associated with Tetanus Neonatorum is DPT (Dermatopontin). The drugs mometasone furoate and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and brain, and related phenotype is behavior/neurological.

Related Diseases for Tetanus Neonatorum

Diseases related to Tetanus Neonatorum via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 cold-induced sweating syndrome 29.5 CNTF CRLF1 KANTR
2 familial glucocorticoid deficiency 12.0
3 glucocorticoid deficiency 4 with or without mineralocorticoid deficiency 11.8
4 left ventricular noncompaction 11.5
5 tetanus 11.5
6 adrenal insufficiency, congenital, with 46,xy sex reversal, partial or complete 11.2
7 intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 11.2
8 cortisone reductase deficiency 11.2
9 adrenal rest tumor 11.2
10 stomach carcinoma in situ 10.2 CRLF1 GLS2
11 hematocele of tunica vaginalis testis 10.2 AFP CRLF1
12 poliomyelitis 10.1
13 spondyloarthropathy 1 10.1
14 radin blood group antigen 10.1
15 horns in sheep 10.1
16 spondylitis 10.1
17 brachial plexus neuritis 10.1 DPT KANTR
18 salpingitis isthmica nodosa 10.1 AVPR2 KANTR
19 maple syrup urine disease 10.1
20 quadriplegia 10.1
21 trigeminal nerve neoplasm 10.0 CRLF1 KANTR
22 neurilemmoma of the fifth cranial nerve 10.0 CRLF1 KANTR
23 paraphimosis 10.0 KANTR NUDT1
24 glossopharyngeal neuralgia 10.0 CRLF1 KANTR
25 oculomotor nerve paralysis 10.0 AFP KANTR
26 third cranial nerve disease 9.9 AFP KANTR
27 crisponi/cold-induced sweating syndrome 1 9.9
28 chronic salpingitis 9.9 AVPR2 KANTR
29 pigmentary disorder, reticulate, with systemic manifestations, x-linked 9.8
30 malaria 9.8
31 autosomal recessive disease 9.8
32 yaws 9.8
33 diphtheria 9.8
34 human immunodeficiency virus infectious disease 9.8
35 measles 9.8
36 cloacal exstrophy 9.8 AFP KANTR
37 transient global amnesia 9.8 CRLF1 KANTR

Graphical network of the top 20 diseases related to Tetanus Neonatorum:



Diseases related to Tetanus Neonatorum

Symptoms & Phenotypes for Tetanus Neonatorum

MGI Mouse Phenotypes related to Tetanus Neonatorum:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.23 AFP AVPR2 CNTF CRLF1 MNT NUDT1

Drugs & Therapeutics for Tetanus Neonatorum

Drugs for Tetanus Neonatorum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
mometasone furoate Approved, Investigational, Vet_approved Phase 3 83919-23-7
2 Immunologic Factors Phase 3
3 Vaccines Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Maternal Immunization With MenAfriVacâ„¢ Recruiting NCT03746665 Phase 3

Search NIH Clinical Center for Tetanus Neonatorum

Genetic Tests for Tetanus Neonatorum

Anatomical Context for Tetanus Neonatorum

MalaCards organs/tissues related to Tetanus Neonatorum:

42
Testes, Skin, Brain, Testis

Publications for Tetanus Neonatorum

Articles related to Tetanus Neonatorum:

(show top 50) (show all 485)
# Title Authors Year
1
Maternal and Neonatal Tetanus Elimination (MNTE) in The WHO African Region. ( 30882092 )
2018
2
Achieving neonatal tetanus elimination in Nigeria: undisclosed challenges and prospects. ( 28147895 )
2018
3
Post-neonatal Tetanus in a PICU of a Developing Economy: Intensive Care Needs, Outcome and Predictors of Mortality. ( 28460120 )
2018
4
Neonatal tetanus in an African newborn. ( 29146512 )
2018
5
Maternal and neonatal tetanus elimination: validation in Punjab Province, Pakistan, November 2016. ( 28116893 )
2017
6
Elimination of Maternal and Neonatal Tetanus in India: A Triumph Tale. ( 28348725 )
2017
7
Eliminating maternal and neonatal tetanus and closing the immunity gap. ( 28402808 )
2017
8
Validation of maternal and neonatal tetanus elimination in Equatorial Guinea, 2016. ( 28622465 )
2017
9
Verification of Neonatal Tetanus Surveillance Systems in Katsina State, Nigeria. ( 28944276 )
2017
10
Long-term outcome in survivors of neonatal tetanus following specialist intensive care in Vietnam. ( 28946862 )
2017
11
Progress towards achieving and maintaining maternal and neonatal tetanus elimination in the African region. ( 29296159 )
2017
12
Epidemiological and clinical aspects of neonatal tetanus from a tertiary care hospital. ( 30805505 )
2017
13
Neonatal tetanus associated with skin infection. ( 27601113 )
2016
14
WHO Declares India Free of Yaws and Maternal and Neonatal Tetanus. ( 27654592 )
2016
15
Neonatal Tetanus: Still a Scourge after Elimination from India. ( 27771660 )
2016
16
Successful elimination of maternal and neonatal tetanus in India: Ray of hope for other nations. ( 27904622 )
2016
17
Maternal and Neonatal Tetanus: A Journey into Oblivion. ( 28064259 )
2016
18
Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality. ( 26407289 )
2016
19
Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies. ( 26904135 )
2016
20
Serological Monitoring Is Key To Sustain Progress of the Maternal and Neonatal Tetanus Elimination Initiative. ( 27226278 )
2016
21
Maternal and neonatal tetanus validation assessment in Region 4, Indonesia, May 2016. ( 27348870 )
2016
22
Tetanus and diphtheria immunity among term and preterm infant-mother pairs in Turkey, a country where maternal and neonatal tetanus have recently been eliminated. ( 25172444 )
2015
23
India is declared free of maternal and neonatal tetanus. ( 26032894 )
2015
24
India is declared free of maternal and neonatal tetanus. ( 26047966 )
2015
25
Vaccines for women for preventing neonatal tetanus. ( 26144877 )
2015
26
RISK CHARACTERIZATION OF MATERNAL AND NEONATAL TETANUS IN VIEW OF TETANUS VACCINATION CAMPAIGNS IN PAKISTAN. ( 26182781 )
2015
27
Maternal and neonatal tetanus elimination: validation survey in 4 States and 2 union territories in India, May 2015. ( 26521303 )
2015
28
Profile and outcome of patients with post-neonatal tetanus in a tertiary centre in south west Nigeria: any remarkable reduction in the scourge? ( 26526006 )
2015
29
Risk factors of neonatal tetanus in Wenzhou, China: a case-control study. ( 26668764 )
2015
30
Maternal and neonatal tetanus. ( 25149223 )
2015
31
Prognosis of neonatal tetanus in the modern management era: an observational study in 107 Vietnamese infants. ( 25499039 )
2015
32
Maternal and neonatal tetanus elimination: from protecting women and newborns to protecting all. ( 25678822 )
2015
33
Maternal and neonatal tetanus elimination: validation surveys in Lao People’s Democratic Republic, December 2013. ( 25682612 )
2015
34
Incidence and risk factors for neonatal tetanus in admissions to Kilifi County Hospital, Kenya. ( 25849440 )
2015
35
Maternal and neonatal tetanus elimination: validation survey in 4 States in India, April 2013. ( 24864342 )
2014
36
A review of neonatal tetanus in University of Maiduguri Teaching Hospital, North-eastern Nigeria. ( 24665154 )
2013
37
Disposable clean delivery kits and prevention of neonatal tetanus in the presence of skilled birth attendants. ( 23261127 )
2013
38
A case of neonatal tetanus presented within 24 hours of life. ( 23443624 )
2013
39
Interventions to reduce neonatal mortality from neonatal tetanus in low and middle income countries--a systematic review. ( 23570611 )
2013
40
Vaccines for women to prevent neonatal tetanus. ( 23728640 )
2013
41
Validation of maternal and neonatal tetanus elimination in United Republic of Tanzania, 2012. ( 23980289 )
2013
42
Three cases of neonatal tetanus in Papua New Guinea lead to development of national action plan for maternal and neonatal tetanus elimination. ( 24015370 )
2013
43
Prognostic factors for mortality in neonatal tetanus: a systematic review and meta-analysis. ( 24145010 )
2013
44
Validation of maternal and neonatal tetanus elimination in Cameroon, 2012. ( 24319784 )
2013
45
HE BURDEN AND CHALLENGES OF NEONATAL TETANUS IN KILIFI DISTRICT, KENYA--2004-7. ( 26866113 )
2013
46
Validation of elimination: maternal and neonatal tetanus in Burkina Faso, 2012. ( 23210146 )
2012
47
Validation of maternal and neonatal tetanus elimination in Timor-Leste,2012. ( 23213668 )
2012
48
Trends in neonatal and post-neonatal tetanus admissions at a Nigerian teaching hospital. ( 23276738 )
2012
49
Neonatal tetanus: a continuing challenge. ( 22227975 )
2012
50
Validation of maternal and neonatal tetanus elimination in Ghana, 2011. ( 22506294 )
2012

Variations for Tetanus Neonatorum

Expression for Tetanus Neonatorum

Search GEO for disease gene expression data for Tetanus Neonatorum.

Pathways for Tetanus Neonatorum

GO Terms for Tetanus Neonatorum

Cellular components related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.17 ACE2 AFP APELA CNTF CRLF1 DPT

Molecular functions related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ciliary neurotrophic factor receptor binding GO:0005127 8.62 CNTF CRLF1

Sources for Tetanus Neonatorum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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