NNT
MCID: TTN001
MIFTS: 29

Tetanus Neonatorum (NNT)

Categories: Infectious diseases

Aliases & Classifications for Tetanus Neonatorum

MalaCards integrated aliases for Tetanus Neonatorum:

Name: Tetanus Neonatorum 12 15 71 32
Neonatal Tetanus 12
Nnt 47

Classifications:



External Ids:

Disease Ontology 12 DOID:13521
ICD9CM 34 771.3
NCIt 49 C116814
SNOMED-CT 67 43424001
ICD10 32 A33
UMLS 71 C0343312

Summaries for Tetanus Neonatorum

Disease Ontology : 12 A tetanus that occurs in newborn babies when the birth cord stump gets dirty through cutting it with an unclean blade or applying substances containing bacteria to it. The infection has symptom stiff body, has symptom muscle spasms, has symptom difficulty in breathing, and has symptom exhaustion.

MalaCards based summary : Tetanus Neonatorum, also known as neonatal tetanus, is related to yaws and familial glucocorticoid deficiency. An important gene associated with Tetanus Neonatorum is MNT (MAX Network Transcriptional Repressor). The drugs mometasone furoate and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and brain.

Related Diseases for Tetanus Neonatorum

Diseases related to Tetanus Neonatorum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 yaws 29.7 MPG ADIRF
2 familial glucocorticoid deficiency 12.2
3 glucocorticoid deficiency 4 with or without mineralocorticoid deficiency 11.9
4 glucose intolerance 11.7
5 left ventricular noncompaction 11.6
6 tetanus 11.6
7 achalasia-addisonianism-alacrima syndrome 11.2
8 microcephaly 1, primary, autosomal recessive 11.2
9 retinitis pigmentosa 22 11.2
10 seckel syndrome 5 11.2
11 intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 11.2
12 cortisone reductase deficiency 11.2
13 poliomyelitis 10.3
14 diphtheria 10.2
15 otitis media 10.1
16 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
17 pertussis 10.1
18 measles 10.1
19 ophthalmia neonatorum 10.1 TMEM106C NSMCE3
20 dracunculiasis 10.1 MPG ADIRF
21 maple syrup urine disease 10.1
22 aspiration pneumonia 10.1
23 bronchopneumonia 10.1
24 quadriplegia 10.1
25 kwashiorkor 10.1
26 hypercarotenemia and vitamin a deficiency, autosomal dominant 10.0
27 cyanosis, transient neonatal 10.0
28 keratomalacia 10.0
29 spasticity 10.0
30 alzheimer disease 10.0
31 spondyloarthropathy 1 10.0
32 atrial standstill 1 10.0
33 parkinson disease, late-onset 10.0
34 scleroderma, familial progressive 10.0
35 cryptorchidism, unilateral or bilateral 10.0
36 diamond-blackfan anemia 2 10.0
37 pulmonary disease, chronic obstructive 10.0
38 congenital hypothyroidism 10.0
39 pain agnosia 10.0
40 hypertrophic cardiomyopathy 10.0
41 inflammatory spondylopathy 10.0
42 varicocele 10.0
43 dilated cardiomyopathy 10.0
44 azoospermia 10.0
45 hypothyroidism 10.0
46 endometriosis 10.0
47 anovulation 10.0
48 infertility 10.0
49 eye disease 10.0
50 spondylitis 10.0

Graphical network of the top 20 diseases related to Tetanus Neonatorum:



Diseases related to Tetanus Neonatorum

Symptoms & Phenotypes for Tetanus Neonatorum

Drugs & Therapeutics for Tetanus Neonatorum

Drugs for Tetanus Neonatorum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
mometasone furoate Approved, Investigational, Vet_approved Phase 3 83919-23-7
2 Vaccines Phase 3
3 Anti-Infective Agents Phase 3
4 Lactoferrin Phase 3
5 Antitoxins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Can Bovine Lactoferrin Prevent Neonatal Infections in Low Birth Weight Babies in Karachi, Sindh, Pakistan. Recruiting NCT03431558 Phase 3 Glucon-D 99.4% (Placebo)
2 Maternal Immunization With MenAfriVacâ„¢ Recruiting NCT03746665 Phase 3
3 Multicenter Study of Tetanus Patients in Fujian Province of China Completed NCT04165928
4 Development and Evaluation of Perinatal Handwashing Promotion for Improved Maternal Handwashing Behavior Completed NCT01309321

Search NIH Clinical Center for Tetanus Neonatorum

Genetic Tests for Tetanus Neonatorum

Anatomical Context for Tetanus Neonatorum

MalaCards organs/tissues related to Tetanus Neonatorum:

40
Testes, Skin, Brain

Publications for Tetanus Neonatorum

Articles related to Tetanus Neonatorum:

(show top 50) (show all 866)
# Title Authors PMID Year
1
Efficiency of placental transfer of vaccine-elicited antibodies relative to prenatal Tdap vaccination status. 61
32482459 2020
2
50 Years Ago in TheJournalofPediatrics: Convulsion Score for Neonatal Tetanus: An Obituary! 61
32446496 2020
3
Antenatal care service delivery and factors affecting effective tetanus vaccine coverage in low- and middle-income countries: Results of the Maternal Immunisation and Antenatal Care Situational analysis (MIACSA) project. 61
32527598 2020
4
Effect of cash incentives on tetanus toxoid vaccination among rural Nigerian women: a randomized controlled trial. 61
31567041 2020
5
Progress Toward Maternal and Neonatal Tetanus Elimination - Worldwide, 2000-2018. 61
32352953 2020
6
The Prevalence and Case-Fatality Rates of Post-Neonatal Tetanus in a Population of Hospitalized Nigerian Children: An 8-Year Retrospective Review. 61
31397484 2020
7
Increasing Frequency of Antenatal Care Visits May Improve Tetanus Toxoid Vaccination Coverage in Pregnant Women in Pakistan. 61
32118509 2020
8
[Immunization to prevent non-neonatal tetanus]. 61
32135606 2020
9
[Guidelines for the use of post-traumatic tetanus vaccines and passive immune preparation]. 61
32164124 2020
10
[Research progress of tetanus antibody detection technology in China]. 61
32074715 2020
11
An investment case for maternal and neonatal tetanus elimination. 61
31980197 2020
12
[Specifications for diagnosis and treatment of non-neonatal tetanus]. 61
32164123 2020
13
Neonatal tetanus in eastern Uganda: improved outcome following the implementation of a neonatal tetanus protocol. 61
31474192 2020
14
Diagnosis and Management of Cryptogenic Occupational Tetanus: A Case Report from Rajasthan, India. 61
32435114 2020
15
Multicenter Study of Tetanus Patients in Fujian Province of China: A Retrospective Review of 95 Cases. 61
32258151 2020
16
Seroprevalence of anti-tetanus antibodies in mothers and cord blood and associated factors in health-care settings in Lao People's Democratic Republic. 61
31735506 2020
17
Tetanus Toxoid Vaccination Uptake and Associated Factors among Mothers Who Gave Birth in the Last 12 Months in Errer District, Somali Regional State, Eastern Ethiopia. 61
32461983 2020
18
Effectiveness of birthing kits for clean childbirth: a systematic review. 61
31340003 2020
19
New immunization strategies: adapting to global challenges. 61
31802153 2020
20
Demography and Symptom Profile of Tetanus: A Cross-sectional Observation in an Infectious Disease Hospital of Bangladesh. 61
31915348 2020
21
Collective memory of umbilical cord stump care: an educational experience. 61
31851274 2019
22
[Improving immunization strategy and promoting the development of tetanus prevention and control in China]. 61
31795575 2019
23
[Guidelines for the use of post-traumatic tetanus vaccines and passive immune preparation]. 61
31795577 2019
24
[Specifications for diagnosis and treatment of non-neonatal tetanus]. 61
31795576 2019
25
[Dramatic achievements in infectious disease prevention and treatment in China during the past 70 years]. 61
32062906 2019
26
The CORE Group Polio Project's Community Volunteers and Polio Eradication in Ethiopia: Self-Reports of Their Activities, Knowledge, and Contributions. 61
31760977 2019
27
Use of Social Mobilization and Community Mobilizers by Non-governmental Health Organizations in Malawi to Support the Eradication of Polio, Improve Routine Immunization Coverage, and Control Measles and Neonatal Tetanus. 61
31760969 2019
28
Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital. 61
31488984 2019
29
Knowledge about and preventive practices against neonatal tetanus among young Nigerian women. 61
31258290 2019
30
SERUM TOTAL IgG AND TETANUS SPECIFIC IgG IN NIGERIAN HUMAN IMMUNODEFICIENCY VIRUS INFECTED PRIMIGRAVIDAE AND THE CORD BLOOD OF THEIR BABIES AT BIRTH. 61
31768150 2019
31
Maternal Immunization and Antenatal Care Situation Analysis (MIACSA) study protocol: a multiregional, cross-sectional analysis of maternal immunization delivery strategies to reduce maternal and neonatal morbidity and mortality. 61
31167857 2019
32
Immunization in Vietnam. 61
31069373 2019
33
Maternal immunization: A call to accelerate progress. 61
31014962 2019
34
Key considerations for successful implementation of maternal immunization programs in low and middle income countries. 61
30676250 2019
35
Tetanus in Poland in 2017 61
31385677 2019
36
Eliminating Maternal and Neonatal Tetanus and Promoting Clean Delivery Practices Through Disposable Clean Birth Kits. 61
31824909 2019
37
A Rare Case of Localized Tetanus. 61
30294137 2018
38
Effects of a community-based data for decision-making intervention on maternal and newborn health care practices in Ethiopia: a dose-response study. 61
30255793 2018
39
Functional and proteomic comparison of different techniques to produce equine anti-tetanus immunoglobulin F(ab')2 fragments. 61
29883887 2018
40
Pre-post effects of a tetanus care protocol implementation in a sub-Saharan African intensive care unit. 61
30161119 2018
41
The crucial role of maternal care providers as vaccinators for pregnant women. 61
28822646 2018
42
Maternal and Neonatal Tetanus Elimination (MNTE) in The WHO African Region. 61
30882092 2018
43
The role of timely initiation of antenatal care on protective dose tetanus toxoid immunization: the case of northern Ethiopia post natal mothers. 61
29907139 2018
44
Determinants and perceptions of the utilization of tetanus toxoid immunization among reproductive-age women in Dukem Town, Eastern Ethiopia: a community-based cross-sectional study. 61
29950171 2018
45
Generalized tetanus in adults without antitetanus booster vaccination in southern Mauritania. 61
29744067 2018
46
Clinical features and outcomes of tetanus: Analysis using a National Inpatient Database in Japan. 61
29304489 2018
47
Post-neonatal Tetanus in a PICU of a Developing Economy: Intensive Care Needs, Outcome and Predictors of Mortality. 61
28460120 2018
48
Neonatal tetanus in an African newborn. 61
29146512 2018
49
[Response capacity and challenges of the Cuban health system against communicable diseasesCapacidade de resposta e desafios do sistema de saúde cubano contra doenças transmissíveis]. 61
31093059 2018
50
Maternal immunisation: What have been the gains? Where are the gaps? What does the future hold? 61
30443339 2018

Variations for Tetanus Neonatorum

Expression for Tetanus Neonatorum

Search GEO for disease gene expression data for Tetanus Neonatorum.

Pathways for Tetanus Neonatorum

GO Terms for Tetanus Neonatorum

Biological processes related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to radiation GO:0071478 8.62 NSMCE3 ADIRF

Sources for Tetanus Neonatorum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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