NNT
MCID: TTN001
MIFTS: 30

Tetanus Neonatorum (NNT)

Categories: Infectious diseases
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Aliases & Classifications for Tetanus Neonatorum

MalaCards integrated aliases for Tetanus Neonatorum:

Name: Tetanus Neonatorum 11 14 71 31 33
Trismus Neonatorum 33
Neonatal Tetanus 11
Newborn Trismus 33
Nnt 47

Classifications:



External Ids:

Disease Ontology 11 DOID:13521
ICD9CM 34 771.3
NCIt 49 C116814
SNOMED-CT 68 43424001
ICD10 31 A33
ICD11 33 2085616610
UMLS 71 C0343312

Summaries for Tetanus Neonatorum

Disease Ontology: 11 A tetanus that occurs in newborn babies when the birth cord stump gets dirty through cutting it with an unclean blade or applying substances containing bacteria to it. The infection has symptom stiff body, has symptom muscle spasms, has symptom difficulty in breathing, and has symptom exhaustion.

MalaCards based summary: Tetanus Neonatorum, also known as trismus neonatorum, is related to tetanus and colorectal cancer. An important gene associated with Tetanus Neonatorum is FCGRT (Fc Gamma Receptor And Transporter), and among its related pathways/superpathways are RAC1 GTPase cycle and RHOQ GTPase cycle. Affiliated tissues include skin and brain, and related phenotype is behavior/neurological.

Related Diseases for Tetanus Neonatorum

Diseases related to Tetanus Neonatorum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 tetanus 11.2
2 colorectal cancer 11.2
3 hepatocellular carcinoma 11.2
4 glucose intolerance 11.1
5 cervical cancer 11.1
6 osteogenic sarcoma 11.1
7 glucocorticoid deficiency 4 with or without mineralocorticoid deficiency 11.1
8 breast cancer 11.1
9 ovarian cancer 11.1
10 familial glucocorticoid deficiency 11.0
11 adrenal insufficiency, congenital, with 46,xy sex reversal, partial or complete 10.9
12 achalasia-addisonianism-alacrima syndrome 10.9
13 microcephaly 1, primary, autosomal recessive 10.9
14 seckel syndrome 5 10.9
15 intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 10.9
16 facial dermatosis 10.9
17 diphtheria 10.3
18 poliomyelitis 10.3
19 lung cancer 10.2
20 pertussis 10.2
21 measles 10.2
22 otitis media 10.1
23 cholangiocarcinoma 10.1
24 keratomalacia 10.1
25 spasticity 10.1
26 non-syndromic x-linked intellectual disability 30 10.1 PAK3 MID2
27 small cell cancer of the lung 10.0
28 premature ovarian failure 7 10.0
29 gastric cancer 10.0
30 inhibited male orgasm 10.0 OXT KANTR
31 episodic ataxia, type 2 10.0
32 maple syrup urine disease 10.0
33 aspiration pneumonia 10.0
34 bronchopneumonia 10.0
35 quadriplegia 10.0
36 kwashiorkor 10.0
37 persistent fetal circulation syndrome 10.0 OXT FCGRT
38 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.0
39 neurodegeneration with brain iron accumulation 2a 10.0
40 crisponi/cold-induced sweating syndrome 1 10.0
41 ataxia with vitamin e deficiency 10.0
42 metabolic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 10.0
43 disease by infectious agent 10.0
44 respiratory failure 10.0
45 cholera 10.0
46 hypertonia 10.0
47 bladder cancer 9.9
48 esophageal cancer 9.9
49 glioma susceptibility 1 9.9
50 renal cell carcinoma, nonpapillary 9.9

Graphical network of the top 20 diseases related to Tetanus Neonatorum:



Diseases related to Tetanus Neonatorum

Symptoms & Phenotypes for Tetanus Neonatorum

MGI Mouse Phenotypes related to Tetanus Neonatorum:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.28 ARHGEF9 CENPJ CRLF1 EBF1 KANTR OPHN1

Drugs & Therapeutics for Tetanus Neonatorum

Search Clinical Trials, NIH Clinical Center for Tetanus Neonatorum

Genetic Tests for Tetanus Neonatorum

Anatomical Context for Tetanus Neonatorum

Organs/tissues related to Tetanus Neonatorum:

MalaCards : Skin, Brain

Publications for Tetanus Neonatorum

Articles related to Tetanus Neonatorum:

(show top 50) (show all 910)
# Title Authors PMID Year
1
Effect of Plasmodium Infection during Pregnancy on Passive Neonatal Immunity against Tetanus Toxoid and Rotavirus. 62
36191874 2022
2
Neonatal and postneonatal tetanus at a referral hospital in Kamsar, Guinea: a retrospective audit of paediatric records (2014-2018). 62
34048561 2022
3
Comparative analysis of antigenic strength and in vivo serum antibodies concentration of tetanus toxoid vaccine adsorbed in Pakistan. 62
35770270 2022
4
Sustaining Maternal and Neonatal Tetanus Elimination (MNTE) in countries that have been validated for elimination - progress and challenges. 62
35395753 2022
5
Progress Toward Achieving and Sustaining Maternal and Neonatal Tetanus Elimination - Worldwide, 2000-2020. 62
35298457 2022
6
Factors associated with maternal tetanus vaccination in Myanmar: An analysis of demographic and health survey data. 62
35067380 2022
7
Neonatal tetanus with good outcomes at a regional referral hospital in Eastern Uganda: a case report. 62
35094701 2022
8
Factors Associated with the Uptake of Antenatal Tetanus Toxoids Containing Vaccine by First-Time Mothers in Nigeria: Findings from the 2018 Nigerian Demographic Health Survey. 62
36157313 2022
9
Prevalence and risk factors associated with rural women's protected against tetanus in East Africa: Evidence from demographic and health surveys of ten East African countries. 62
35324988 2022
10
A ten-year review of neonatal tetanus cases managed at a tertiary health facility in a resource poor setting: The trend, management challenges and outcome. 62
34874950 2021
11
Progress and barriers towards maternal and neonatal tetanus elimination in the remaining 12 countries: a systematic review. 62
34678200 2021
12
[Elimination of infectious disease in China, past and future]. 62
34818832 2021
13
Impact of childhood and maternal vaccination against diphtheria, tetanus, and pertussis in Colombia. 62
34751533 2021
14
Maternal immunization: trends in South and Southeast Asian countries. 62
34517746 2021
15
Monitoring progress of maternal and neonatal immunization in Latin America and the Caribbean. 62
33715899 2021
16
Vaccination in the Philippines: experiences from history and lessons for the future. 62
33357156 2021
17
Toxin-associated infectious diseases: tetanus, botulism and diphtheria. 62
33840775 2021
18
Individual and community-level determinants of poor tetanus toxoid immunization among pregnant women in Ethiopia using data from 2016 Ethiopian demographic and health survey; multilevel analysis. 62
34088345 2021
19
Performance of the Neonatal Tetanus Surveillance System (NTSS) in Sana'a, Yemen: Evaluation Study. 62
33944794 2021
20
Bayesian Analysis of Trends in Utilization of Maternal Healthcare Services in Pakistan during 2006-2018. 62
34873415 2021
21
Factors associated with births protected against neonatal tetanus in Africa: Evidences from Demographic and health surveys of five African countries. 62
34138922 2021
22
Characterization of National Immunization Programs in the Context of Public Health Emergencies: A Case Study of 13 Countries in the WHO Africa Region. 62
34650952 2021
23
Tetanus in a rural low-income intensive care unit setting. 62
33824951 2021
24
Tetanus Toxoid Vaccination Coverage and Associated Factors among Childbearing Women in Ethiopia: A Systematic Review and Meta-Analysis. 62
34790820 2021
25
Maternal and Neonatal Tetanus Elimination: Where are We Now? 62
34849046 2021
26
Effects of immunization program on morbidity and mortality rates ofvaccine-preventable diseases in Turkey 62
33128356 2020
27
Neonatal tetanus in St. Mary's Hospital Lacor: A case report. 62
33235766 2020
28
The association between area of residence and sufficient antenatal tetanus vaccination in women ages 15-49 in Afghanistan: an analysis of the 2015 DHS dataset. 62
33292868 2020
29
Seroprevalence of Measles, Rubella, Tetanus, and Diphtheria Antibodies among Children in Haiti, 2017. 62
32618256 2020
30
Knowledge and health beliefs of reproductive-age women in Alexandria about tetanus toxoid immunization. 62
32852679 2020
31
Provincial-level outcomes of China's 'Reducing maternal mortality and eliminating neonatal tetanus' program. 62
32770045 2020
32
Neonatal Tetanus in a Nomadic Population in South India: A Clinicosocial Case Study. 62
33354027 2020
33
Increasing Frequency of Antenatal Care Visits May Improve Tetanus Toxoid Vaccination Coverage in Pregnant Women in Pakistan. 62
32118509 2020
34
Antenatal care service delivery and factors affecting effective tetanus vaccine coverage in low- and middle-income countries: Results of the Maternal Immunisation and Antenatal Care Situational analysis (MIACSA) project. 62
32527598 2020
35
Efficiency of placental transfer of vaccine-elicited antibodies relative to prenatal Tdap vaccination status. 62
32482459 2020
36
50 Years Ago in TheJournalofPediatrics: Convulsion Score for Neonatal Tetanus: An Obituary! 62
32446496 2020
37
Progress Toward Maternal and Neonatal Tetanus Elimination - Worldwide, 2000-2018. 62
32352953 2020
38
Effect of cash incentives on tetanus toxoid vaccination among rural Nigerian women: a randomized controlled trial. 62
31567041 2020
39
The Prevalence and Case-Fatality Rates of Post-Neonatal Tetanus in a Population of Hospitalized Nigerian Children: An 8-Year Retrospective Review. 62
31397484 2020
40
[Immunization to prevent non-neonatal tetanus]. 62
32135606 2020
41
[Research progress of tetanus antibody detection technology in China]. 62
32074715 2020
42
[Guidelines for the use of post-traumatic tetanus vaccines and passive immune preparation]. 62
32164124 2020
43
[Specifications for diagnosis and treatment of non-neonatal tetanus]. 62
32164123 2020
44
An investment case for maternal and neonatal tetanus elimination. 62
31980197 2020
45
Multicenter Study of Tetanus Patients in Fujian Province of China: A Retrospective Review of 95 Cases. 62
32258151 2020
46
Tetanus Toxoid Vaccination Uptake and Associated Factors among Mothers Who Gave Birth in the Last 12 Months in Errer District, Somali Regional State, Eastern Ethiopia. 62
32461983 2020
47
Determinants of births protected against neonatal tetanus in Ethiopia: A multilevel analysis using EDHS 2016 data. 62
33259554 2020
48
Neonatal tetanus in eastern Uganda: improved outcome following the implementation of a neonatal tetanus protocol. 62
31474192 2020
49
Demography and Symptom Profile of Tetanus: A Cross-sectional Observation in an Infectious Disease Hospital of Bangladesh. 62
31915348 2020
50
Seroprevalence of anti-tetanus antibodies in mothers and cord blood and associated factors in health-care settings in Lao People's Democratic Republic. 62
31735506 2020

Variations for Tetanus Neonatorum

Expression for Tetanus Neonatorum

Search GEO for disease gene expression data for Tetanus Neonatorum.

Pathways for Tetanus Neonatorum

Pathways related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.46 PAK3 OPHN1 FGD1 ARHGEF9
2
Show member pathways
11.19 PAK3 OPHN1 ARHGEF9
3 10.92 PAK3 ARHGEF9
4 10.65 FGD1 ARHGEF9

GO Terms for Tetanus Neonatorum

Biological processes related to Tetanus Neonatorum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of urine volume GO:0035811 8.92 SLC4A1 OXT

Sources for Tetanus Neonatorum

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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