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MCID: TTH004
MIFTS: 41

Tethered Spinal Cord Syndrome

Categories: Neuronal diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Tethered Spinal Cord Syndrome

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MalaCards integrated aliases for Tethered Spinal Cord Syndrome:

Name: Tethered Spinal Cord Syndrome 12 55 15 17
Spinal Dysraphism 12 30 6
Tethered Spinal Cord Disease 77

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 34


External Ids:

Disease Ontology 12 DOID:1089
ICD9CM 36 741
MeSH 45 D016135
NCIt 51 C101214
SNOMED-CT 69 67531005
ICD10 34 Q05 Q05.9
UMLS 74 C0080178
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Summaries for Tethered Spinal Cord Syndrome

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NINDS : 55 Tethered spinal cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column.  Attachments may occur congenitally at the base of the spinal cord (conus medullaris) or they may develop near the site of an injury to the spinal cord.  These attachments cause an abnormal stretching of the spinal cord.  The course of the disorder is progressive.  In children, symptoms may include lesions, hairy patches, dimples, or fatty tumors on the lower back; foot and spinal deformities; weakness in the legs; low back pain; scoliosis; and incontinence.  This type of tethered spinal cord syndrome appears to be the result of improper growth of the neural tube during fetal development, and is closely linked to spina bifida.  Tethered spinal cord syndrome may go undiagnosed until adulthood, when pain, sensory and motor problems, and loss of bowel and bladder control emerge.  This delayed presentation of symptoms is related to the degree of strain placed on the spinal cord over time and may be exacerbated during sports or pregnancy, or may be due to narrowing of the spinal column (stenosis) with age. Tethering may also develop after spinal cord injury and scar tissue can block the flow of fluids around the spinal cord.  Fluid pressure may cause cysts to form in the spinal cord, a condition called syringomyelia.  This can lead to additional loss of movement, feeling or the onset of pain or autonomic symptoms.

MalaCards based summary : Tethered Spinal Cord Syndrome, also known as spinal dysraphism, is related to anus, imperforate and neural tube defects. An important gene associated with Tethered Spinal Cord Syndrome is COX8C (Cytochrome C Oxidase Subunit 8C). The drugs Acetylcholine and Oxybutynin have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, colon and brain, and related phenotype is cellular.

Wikipedia : 77 Tethered cord syndrome (TCS) refers to a group of neurological disorders that relate to malformations of... more...

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Related Diseases for Tethered Spinal Cord Syndrome

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Diseases related to Tethered Spinal Cord Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 anus, imperforate 29.8 KIDINS220 MNX1
2 neural tube defects 11.8
3 split spinal cord malformation 11.5
4 tethered cord syndrome 11.4
5 primary tethered cord syndrome 11.4
6 exstrophy of bladder 11.2
7 myelocystocele 10.3
8 epidermoid cysts 10.2
9 hydrocephalus 10.2
10 scoliosis 10.2
11 syringomyelia 10.2
12 myelomeningocele 10.1
13 anorectal anomalies 10.1
14 wilms tumor 5 10.1
15 wilms tumor 6 10.1
16 latex allergy 10.1
17 dermoid cyst 10.1
18 teratoma 10.1
19 lipomatosis, multiple 10.0
20 currarino syndrome 10.0
21 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.0
22 hemangioma 10.0
23 pain agnosia 10.0
24 spina bifida occulta 10.0
25 pleomorphic lipoma 10.0
26 hypertrichosis 10.0
27 situs inversus 10.0
28 meningitis 10.0
29 chiari malformation 10.0
30 dextrocardia with situs inversus 10.0
31 myoclonus 10.0
32 syringohydromyelia 10.0
33 hydromyelia 10.0
34 congenital coronary artery aneurysm 10.0
35 diastematomyelia 10.0
36 encephalocraniocutaneous lipomatosis 10.0
37 neurogenic bladder 10.0
38 lipomatosis 10.0
39 achondroplasia 9.9
40 acroosteolysis 9.9
41 cleft palate, isolated 9.9
42 vesicoureteral reflux 1 9.9
43 anencephaly 9.9
44 chiari malformation type ii 9.9
45 oeis complex 9.9
46 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 9.9
47 yemenite deaf-blind hypopigmentation syndrome 9.9
48 anxiety 9.9
49 lipomyelomeningocele 9.9
50 spondylocostal dysostosis 3, autosomal recessive 9.9

Graphical network of the top 20 diseases related to Tethered Spinal Cord Syndrome:



Diseases related to Tethered Spinal Cord Syndrome
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Symptoms & Phenotypes for Tethered Spinal Cord Syndrome

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MGI Mouse Phenotypes related to Tethered Spinal Cord Syndrome:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 GLIS3 HOXA1 KIDINS220 MNX1 NKX2-8
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Drugs & Therapeutics for Tethered Spinal Cord Syndrome

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Drugs for Tethered Spinal Cord Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 166)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4,Phase 3 51-84-3 187
2
Oxybutynin Approved, Investigational Phase 4,Phase 3 5633-20-5 4634
3
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
4
Glycerol Approved, Investigational Phase 4 56-81-5 753
5 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
6 abobotulinumtoxinA Phase 4,Phase 3
7 Botulinum Toxins Phase 4,Phase 3
8 Neuromuscular Agents Phase 4,Phase 3
9 Acetylcholine Release Inhibitors Phase 4,Phase 3
10 Cholinergic Agents Phase 4,Phase 3
11 Neurotransmitter Agents Phase 4,Phase 3
12 Botulinum Toxins, Type A Phase 4,Phase 3
13 Mandelic Acids Phase 4,Phase 3
14 Renal Agents Phase 4,Phase 3
15 Muscarinic Antagonists Phase 4,Phase 3
16 Anti-Infective Agents, Urinary Phase 4,Phase 3
17 Cholinergic Antagonists Phase 4,Phase 3
18 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
19 Autonomic Agents Phase 4,Phase 3
20 Parasympatholytics Phase 4,Phase 3
21 Anti-Infective Agents, Local Phase 4,Not Applicable
22 Chlorhexidine gluconate Phase 4
23 Disinfectants Phase 4
24 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
25 Pharmaceutical Solutions Phase 4,Phase 1,Not Applicable
26 Protective Agents Phase 4,Phase 3,Early Phase 1
27 Cola Phase 4,Not Applicable
28
leucovorin Approved Phase 3,Phase 1,Not Applicable 58-05-9 6006 143
29
Polyestradiol phosphate Approved Phase 3 28014-46-2
30
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
31
Drospirenone Approved Phase 3 67392-87-4 68873
32
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
33
Methylcobalamin Approved, Experimental, Investigational Phase 3,Not Applicable 13422-55-4
34
Hydroxocobalamin Approved Phase 3,Not Applicable 13422-51-0 11953898 15589840
35
Iodine Approved, Investigational Phase 3 7553-56-2 807
36
Nicotinamide Approved, Investigational Phase 3 98-92-0 936
37 Orange Approved Phase 3
38
Copper Approved, Investigational Phase 3 7440-50-8 27099
39
Tocopherol Approved, Investigational Phase 3 1406-66-2 14986
40
Iron Approved, Experimental Phase 3 7439-89-6, 15438-31-0 23925 27284
41
Selenium Approved, Investigational, Vet_approved Phase 3 7782-49-2
42
Zinc Approved, Investigational Phase 3 7440-66-6 32051
43
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Not Applicable 59-30-3 6037
44
Calcium Approved, Nutraceutical Phase 3,Not Applicable 7440-70-2 271
45
Cyanocobalamin Approved, Nutraceutical Phase 3,Not Applicable 68-19-9 44176380
46
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
47
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 3 59-43-8, 70-16-6 1130
48
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 3 83-88-5 493570
49
Niacin Approved, Investigational, Nutraceutical Phase 3 59-67-6 938
50
Vitamin C Approved, Nutraceutical Phase 3,Early Phase 1 50-81-7 5785 54670067

Interventional clinical trials:

(show top 50) (show all 145)
# Name Status NCT ID Phase Drugs
1 Effect of Botulinum Toxin in Neurogenic Bladders in Children With Myelomeningocele Unknown status NCT00175123 Phase 4 Botulinum A toxin
2 Safety and Efficacy Study of Transdermal Oxybutynin to Treat Overactive Bladder With a Neurological Condition Completed NCT00224016 Phase 4 Oxybutynin;Oxybutynin
3 Post-Operative Colonization Rates of Femoral Nerve Catheters Treated With Chlorhexidine-Impregnated Patch Completed NCT01411891 Phase 4
4 A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children Recruiting NCT02435069 Phase 4 NS and USP Glycerin - Dose Response;NS and USP Glycerin - Effectiveness
5 Folic Acid Dosage and Malformations Reduction Unknown status NCT01244347 Phase 3 folic acid;folic acid
6 Efficacy and Safety Study for an Oral Contraceptive Containing Folate Completed NCT00468481 Phase 3 Drospirenone/Ethinylestradiol/Methyltetrahydrofolate;Drospirenone/Ethinylestradiol (Yaz)
7 Children Toxine Botulinum Detrusor Injection in Neurogenic Vesical Hyperactivity Syndrom: Non Inferiority Multicenter Controlled Therapeutic Study Between Two Reported Weight's Doses Completed NCT02816151 Phase 3 full dose at 16 UI/kg for Dysport or 6,5 UA/kg for Botox;half dose at 8 UI/kg for Dysport or 3,25 UA/kg for Botox
8 Botox Versus Oxybutynin as First Line Treatment for the Poorly Compliant Pediatric Neurogenic Bladder Completed NCT01716624 Phase 3 Oxybutynin;Botulinum Toxin A injection
9 Study of Treatment With the Combination of Drospirenone Plus Ethinyl Estradiol Plus Levomefolate Calcium in Mexican Women Seeking Contraception Completed NCT01902264 Phase 3 EE20/DRSP/L-5-MTHF (Beyaz, BAY98-7071)
10 Duragen Versus Duraguard in Chiari Surgery Completed NCT00741858 Phase 3
11 Randomized Controlled Trial of Shunt vs ETV/CPC for PIH in Ugandan Infants Active, not recruiting NCT01936272 Phase 3
12 Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes Active, not recruiting NCT01665378 Phase 3
13 A Study to Evaluate Folate Levels in Women Taking Oral Contraceptives Withdrawn NCT00301587 Phase 3 Norgestimate-ethinyl estradiol, with or without folic acid
14 Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence Unknown status NCT01867268 Phase 2 Acetazolamide
15 Lumbar to Sacral Ventral Nerve Re-Routing Completed NCT00378664 Phase 2
16 Coping Skills Training (CST) for Children With Chronic Health Conditions Completed NCT00359775 Phase 2
17 Post T-plant Infusion of Allogeneic Cytokine Induced Killer Cells as Consolidative Therapy in Myelodysplastic Syndromes/Myeloproliferative Disorders Completed NCT01392989 Phase 2 CIK cells;Cyclosporine;Mycophenolate Mofetil;Thymoglobulin
18 Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB Active, not recruiting NCT02748356 Phase 2 Lactobacillus
19 Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB Active, not recruiting NCT02748317 Phase 2 Lactobacillus rhamnosus GG
20 Augmentation Cystoplasty Using an Autologous Neo-Bladder Terminated NCT00419120 Phase 2
21 Probiotics in Girls With Spina Bifida Withdrawn NCT00767988 Phase 2
22 Efficacy of Acetaminophen in Posterior Fossa Surgery Withdrawn NCT02532322 Phase 2 IV acetaminophen;normal saline
23 Bacteriuria Eradication Through Probiotics Unknown status NCT00717600 Phase 1
24 Does Mid-Gestation Placental Function Assessment Reduce Psychological Distress in Women With High-Risk Pregnancies? Unknown status NCT00546026 Phase 1
25 Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study) Completed NCT00452829 Phase 1 Folic Acid and inositol;Folic acid and placebo
26 Patch vs. No Patch Fetoscopic Meningomyelocele Repair Study Recruiting NCT03794011 Phase 1
27 Fetoscopic Meningomyelocele Repair Study Active, not recruiting NCT02230072 Phase 1
28 Pain Biomarker Study Active, not recruiting NCT03511846 Phase 1 Oral capsaicin;Topical capsaicin;Intranasal capsaicin;Low Flow Oxygen;High Flow Oxygen
29 Genetics of Neural Tube Defects Unknown status NCT01253746
30 Incidence of Pregnancies and Births With Spina Bifida in Denmark in 2008-2014 Unknown status NCT02685813
31 Study of Genetic Risk Factors for Spina Bifida and Anencephaly Unknown status NCT00031122
32 Assessment of Functional Independence and Quality of Life in Adolescents With Spina Bifid Unknown status NCT00966927
33 The LETS Study: A Longitudinal Evaluation of Transition Services Unknown status NCT00975338
34 Effect of Psycho-education on Gestational Weight Gain and Anxiety/Depression in Obese Pregnant Women Unknown status NCT01329835 Not Applicable
35 Cuff Pressure in Infants Unknown status NCT03088761
36 Dural Graft Equivalent Comparison Trial Unknown status NCT01667770 Not Applicable
37 Chiari Study Looking at Use of Duragen Versus Duraguard Unknown status NCT00565435
38 Reciprocating Gait Orthoses for Paraplegia Patients Unknown status NCT02227407 Not Applicable
39 Comparison of Four Questionnaires for OSA Screening in China Unknown status NCT03074747
40 Hemangioma Associated With High Rates of Morbidity Completed NCT00394888 Not Applicable
41 Treatment of Persistent Urinary Incontinence in Children Completed NCT00124046 Not Applicable
42 Improving Genetic Counseling for Patients With Spina Bifida Using Next Generation Sequencing Completed NCT02854150
43 Comparing Urinary Tract Infections in Children With Spina Bifida Using Two Types of Catheters for Catheterization Completed NCT01263392 Not Applicable
44 Outcome of Fetal Spina Bifida Completed NCT01100697
45 An Audit of the Posterior Fossa Characterization in Open Spina Bifida Based on Tertiary Center Experience Completed NCT03544970
46 Urinary Markers of Detrusor Overactivity in Spina Bifida Patients Completed NCT02852317
47 The Relationship Between Nocturnal Enuresis And Spina Bifida Occulta Completed NCT03543995
48 Cognitive Rehabilitation in Patients With Spina Bifida Completed NCT01302314 Not Applicable
49 Management of Myelomeningocele Study (MOMS) Completed NCT00060606 Not Applicable
50 Sterile Single-use vs Reused Polyvinylchloride Catheter For Intermittent Catheterization In Neurogenic Bladder Completed NCT03424499 Not Applicable

Search NIH Clinical Center for Tethered Spinal Cord Syndrome

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Genetic Tests for Tethered Spinal Cord Syndrome

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Genetic tests related to Tethered Spinal Cord Syndrome:

# Genetic test Affiliating Genes
1 Spinal Dysraphism 30
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Anatomical Context for Tethered Spinal Cord Syndrome

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MalaCards organs/tissues related to Tethered Spinal Cord Syndrome:

42
Spinal Cord, Colon, Brain, Bone, Testes, Prostate, Skin
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Publications for Tethered Spinal Cord Syndrome

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Articles related to Tethered Spinal Cord Syndrome:

(show top 50) (show all 306)
# Title Authors Year
1
Complex spinal dysraphism: myelomenigocele associated with dorsal bony spur, split cord malformation type I, syringomyelia, lipoma and tethered cord. ( 30836021 )
2019
2
Intramedullary and Extramedullary Thoracic Spinal Lipomas Without Spinal Dysraphism: Clinical Presentation and Surgical Management. ( 30315981 )
2019
3
Impact of the associated anorectal malformation on the outcome of spinal dysraphism after untethering surgery. ( 30390136 )
2019
4
Ben W. Lichtenstein (1908-2003) and his contributions to our knowledge of spinal dysraphism. ( 30826956 )
2019
5
Outcomes of Intradetrusor OnabotulinumtoxinA Injection in Adults with Congenital Spinal Dysraphism in Tertiary Transitional Urology Clinic. ( 30906822 )
2019
6
Combined Spinal Arteriovenous Malformation and Spinal Dysraphism. ( 29223517 )
2018
7
Contiguous Diastematomyelia with lipomyelomeningocele in each hemicord-An exceptional case of spinal dysraphism. ( 30529523 )
2018
8
Fatty filum terminale (FFT) as a secondary tethering element in children with closed spinal dysraphism. ( 29260294 )
2018
9
Spinal dysraphism in a 63-year-old multipara faun-tailed woman. ( 29316813 )
2018
10
Spinal Dysraphism Presenting as a Translucent Papule in a Man. ( 29541754 )
2018
11
Spinal dysraphism and dislocated hip: Beware of anomalous sciatic nerve through Ilium, a case report. ( 29561460 )
2018
12
Intradetrusor Injections of Botulinum Toxin A in Adults with Spinal Dysraphism. ( 29746860 )
2018
13
Adult intramedullary epidermoid cyst without spinal dysraphism: A case report. ( 30009086 )
2018
14
Dorcas Padget (1906-1973) and her contributions to spinal dysraphism and Chiari II malformations. ( 30066163 )
2018
15
Comparison of neurogenic lower urinary tract dysfunctions in open versus closed spinal dysraphism: A prospective cross-sectional study of 318 patients. ( 30070396 )
2018
16
Ultrasound guided transversus abdominis plane block. Postoperative analgesia in children with spinal dysraphism. ( 29332115 )
2018
17
Decreased rectal meconium signal on MRI in fetuses with open spinal dysraphism. ( 30094854 )
2018
18
Dorsal accessory ectopic breast with polythelia - A marker of occult spinal dysraphism. ( 30105137 )
2018
19
Dorsal midline cutaneous stigmata associated with occult spinal dysraphism in pediatric patients. ( 30304899 )
2018
20
Anaesthetic management for caesarean section of a parturient with a known difficult airway and closed spinal dysraphism. ( 30415798 )
2018
21
Reliability of MR Imaging-Based Posterior Fossa and Brain Stem Measurements in Open Spinal Dysraphism in the Era of Fetal Surgery. ( 30591508 )
2018
22
Dynamic magnetic resonance imaging parameters for objective assessment of the magnitude of tethered cord syndrome in patients with spinal dysraphism. ( 30456429 )
2018
23
Streamlining risk stratification in infants and young children with spinal dysraphism: Vesicoureteral reflux and/or bladder trabeculations outperforms other urodynamic findings for predicting adverse outcomes. ( 30253979 )
2018
24
Faun Tail Nevus: A Cutaneous Sign of Spinal Dysraphism. ( 27208911 )
2017
25
Unjoined primary and secondary neural tubes: junctional neural tube defect, a new form of spinal dysraphism caused by disturbance of junctional neurulation. ( 27796548 )
2017
26
Use of magnetic resonance imaging to detect occult spinal dysraphism in infants. ( 27911245 )
2017
27
Spinal dysraphism with tripedus: A child with three legs. ( 28084286 )
2017
28
Occult sacral meningocoele associated with spinal dysraphism: Report of an unusual case and a review of literature. ( 28290420 )
2017
29
Imaging spectrum of spinal dysraphism on magnetic resonance: A pictorial review. ( 28529681 )
2017
30
Predictors of permanent disability among adults with spinal dysraphism. ( 28548634 )
2017
31
Reoperation in Spinal Dysraphism: Does it Help in Reversing the Neurological Deficits? ( 28694616 )
2017
32
Expectant use of CIC in newborns with spinal dysraphism: Report of clinical outcomes. ( 29125524 )
2017
33
Reoperation in Spinal Dysraphism. ( 29204003 )
2017
34
Spinal dysraphism illustrated; Embroyology revisited. ( 29379236 )
2017
35
Should the Macular Lesions Around Spinal Dysraphism Be Excised? Analysis of Macular Lesions Accompanying Spinal Dysraphism. ( 29399749 )
2017
36
Association between chromosomal aberration of COX8C and tethered spinal cord syndrome: array-based comparative genomic hybridization analysis. ( 27651783 )
2016
37
[Surgical treatment outcomes in children with tethered spinal cord syndrome. A prognosis on the basis of spinal 3T MRI tractography]. ( 27296539 )
2016
38
Spinal dysraphism masking the presentation of spinal dural arteriovenous fistula: A serendipitous development or a congenital predisposition to an early-onset variant of spinal dural arteriovenous fistula? ( 27841239 )
2016
39
Small Biparietal Diameter in Spinal Dysraphism: Do Not Forget the Quality Control of the Measure. ( 26227861 )
2016
40
Long faun tail: a rare cutaneous marker of spinal dysraphism. ( 26376040 )
2016
41
Neurological disease of Şehzade Cihangir in the Ottoman history: spinal dysraphism. ( 26590593 )
2016
42
A rare cause of spinal dysraphism: lipomeningomyelocele. ( 26723259 )
2016
43
Neonatal Lumbosacral Ulceration Masking Lumbosacral and Intraspinal Hemangiomas Associated with Occult Spinal Dysraphism. ( 27215780 )
2016
44
Association of Obesity, BMI, and Hispanic Ethnicity on Ambulatory Status in Children with Spinal Dysraphism followed near the California-Mexico Border. ( 27818449 )
2016
45
Perceived barriers and difficulties of intermittent catheterization: In Korean patients with spinal dysraphism and their parents. ( 25546707 )
2016
46
Encephalocraniocutaneous Lipomatosis: A Rare Association With Tethered Spinal Cord Syndrome With Review of Literature. ( 28503585 )
2015
47
A lumbosacral hemangioma with spinal dysraphism. ( 25449217 )
2015
48
Intra-medullary tubercular abscess with spinal dysraphism: An unusual case. ( 25878753 )
2015
49
Urinary considerations for adult patients with spinal dysraphism. ( 25963964 )
2015
50
Dorsal ectopic breast in a case of spinal dysraphism: A rare entity. ( 26053812 )
2015
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Variations for Tethered Spinal Cord Syndrome

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Expression for Tethered Spinal Cord Syndrome

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Search GEO for disease gene expression data for Tethered Spinal Cord Syndrome.
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Pathways for Tethered Spinal Cord Syndrome

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GO Terms for Tethered Spinal Cord Syndrome

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Biological processes related to Tethered Spinal Cord Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anatomical structure morphogenesis GO:0009653 8.96 HOXA1 MNX1
2 transcription by RNA polymerase II GO:0006366 8.62 GLIS3 NKX2-8

Molecular functions related to Tethered Spinal Cord Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.46 GLIS3 HOXA1 MNX1 NKX2-8
2 sequence-specific DNA binding GO:0043565 9.13 HOXA1 MNX1 NKX2-8
3 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 8.92 GLIS3 HOXA1 MNX1 NKX2-8
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Sources for Tethered Spinal Cord Syndrome

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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