MCID: THL002
MIFTS: 22

Thalamic Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Thalamic Neoplasm

MalaCards integrated aliases for Thalamic Neoplasm:

Name: Thalamic Neoplasm 12 15 71
Malignant Neoplasm of Thalamus 12
Malignant Tumor of Thalamus 12
Tumor of Thalamus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6098
NCIt 49 C4576 C6221
SNOMED-CT 67 188287005
UMLS 71 C0346902 C1336733

Summaries for Thalamic Neoplasm

MalaCards based summary : Thalamic Neoplasm, also known as malignant neoplasm of thalamus, is related to adult oligodendroglioma and childhood oligodendroglioma. An important gene associated with Thalamic Neoplasm is ANAPC1 (Anaphase Promoting Complex Subunit 1), and among its related pathways/superpathways is NF-kappaB Signaling. Affiliated tissues include thalamus, and related phenotypes are Decreased HPV16-GFP infection and hematopoietic system

Related Diseases for Thalamic Neoplasm

Graphical network of the top 20 diseases related to Thalamic Neoplasm:



Diseases related to Thalamic Neoplasm

Symptoms & Phenotypes for Thalamic Neoplasm

GenomeRNAi Phenotypes related to Thalamic Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased HPV16-GFP infection GR00350-A 8.62 LCK TLR3

MGI Mouse Phenotypes related to Thalamic Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.43 F2 LCK MYBL1 TBK1 TLR3 UNK
2 immune system MP:0005387 9.17 F2 KIAA1549 LCK MYBL1 TBK1 TLR3

Drugs & Therapeutics for Thalamic Neoplasm

Search Clinical Trials , NIH Clinical Center for Thalamic Neoplasm

Genetic Tests for Thalamic Neoplasm

Anatomical Context for Thalamic Neoplasm

MalaCards organs/tissues related to Thalamic Neoplasm:

40
Thalamus

Publications for Thalamic Neoplasm

Articles related to Thalamic Neoplasm:

# Title Authors PMID Year
1
Vaginal allodynia as the presentation of a thalamic tumor. 61
21257264 2011
2
High-grade dural arteriovenous fistula simulating a bilateral thalamic neoplasm. 61
19482418 2009
3
Parainfectious optic neuritis and encephalomyelitis. A report of two cases with thalamic involvement. 61
8099089 1993
4
Gyratory epilepsy in a patient with a thalamic neoplasm. 61
1396424 1992
5
Atypical spasmus nutans as an initial sign of thalamic neoplasm. 61
3508712 1986

Variations for Thalamic Neoplasm

Expression for Thalamic Neoplasm

Search GEO for disease gene expression data for Thalamic Neoplasm.

Pathways for Thalamic Neoplasm

Pathways related to Thalamic Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.31 TLR3 TBK1 LCK

GO Terms for Thalamic Neoplasm

Biological processes related to Thalamic Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 I-kappaB kinase/NF-kappaB signaling GO:0007249 9.32 TLR3 TBK1
2 positive regulation of type I interferon production GO:0032481 9.26 TLR3 TBK1
3 TRIF-dependent toll-like receptor signaling pathway GO:0035666 9.16 TLR3 TBK1
4 positive regulation of interferon-beta production GO:0032728 8.96 TLR3 TBK1
5 positive regulation of interferon-beta biosynthetic process GO:0045359 8.62 TLR3 TBK1

Molecular functions related to Thalamic Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein phosphatase binding GO:0019903 8.62 TBK1 LCK

Sources for Thalamic Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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