MCID: THL004
MIFTS: 31

Theileriasis

Categories: Infectious diseases

Aliases & Classifications for Theileriasis

MalaCards integrated aliases for Theileriasis:

Name: Theileriasis 12 44 15 17 71
Theileriosis 12 54
Infection by Theileria 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3733
MeSH 44 D013801
SNOMED-CT 67 68771000
UMLS 71 C0039753

Summaries for Theileriasis

Disease Ontology : 12 A parasitic protozoa infectious disease that involves infection of humans and cattle caused by a genus of parasitic protozoa Theileria, which is transmitted by ixodid ticks.

MalaCards based summary : Theileriasis, also known as theileriosis, is related to babesiosis and tick infestation. An important gene associated with Theileriasis is CSNK2A2 (Casein Kinase 2 Alpha 2), and among its related pathways/superpathways are NF-KappaB Family Pathway and AGE-RAGE signaling pathway in diabetic complications. Affiliated tissues include salivary gland, monocytes and spinal cord.

Wikipedia : 74 Theileria is a genus of parasites that belongs to the phylum Apicomplexa, and is closely related to... more...

Related Diseases for Theileriasis

Diseases related to Theileriasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 babesiosis 30.1 RPS8 MT-CYB
2 tick infestation 10.3
3 posttransplant acute limbic encephalitis 10.2
4 lymphopenia 10.1
5 mucocutaneous leishmaniasis 10.0 TNF MT-CYB
6 retinitis pigmentosa 47 10.0 MT-CYB ABR
7 superficial basal cell carcinoma 10.0 TNF TLR10
8 taeniasis 10.0 TNF MT-CYB
9 deficiency anemia 10.0
10 hemolytic anemia 10.0
11 vasculitis 10.0
12 abetalipoproteinemia 9.8
13 anemia, hypochromic microcytic, with iron overload 1 9.8
14 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.8
15 myelofibrosis 9.8
16 yemenite deaf-blind hypopigmentation syndrome 9.8
17 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.8
18 disease by infectious agent 9.8
19 hypochromic microcytic anemia 9.8
20 atrioventricular block 9.8
21 lymphoproliferative syndrome 9.8
22 trypanosomiasis 9.8
23 endocarditis 9.8
24 mastitis 9.8
25 neutropenia 9.8
26 arthus reaction 9.8
27 thrombocytopenia 9.8
28 constipation 9.8
29 splenic infarction 9.8
30 vaccinia 9.8
31 hemoglobinuria 9.8
32 conjunctivitis 9.8
33 neonatal leukemia 9.8
34 parasitic helminthiasis infectious disease 9.8
35 sarcocystosis 9.8
36 pathologic nystagmus 9.8
37 hypereosinophilic syndrome 9.8
38 47,xyy 9.8
39 cytokine deficiency 9.8
40 optic nerve disease 9.6 TNF MT-CYB JUN
41 hemorrhagic cystitis 9.5 TNF JUN

Graphical network of the top 20 diseases related to Theileriasis:



Diseases related to Theileriasis

Symptoms & Phenotypes for Theileriasis

Drugs & Therapeutics for Theileriasis

Search Clinical Trials , NIH Clinical Center for Theileriasis

Cochrane evidence based reviews: theileriasis

Genetic Tests for Theileriasis

Anatomical Context for Theileriasis

MalaCards organs/tissues related to Theileriasis:

40
Salivary Gland, Monocytes, Spinal Cord, T Cells

Publications for Theileriasis

Articles related to Theileriasis:

(show top 50) (show all 812)
# Title Authors PMID Year
1
Assignment of the casein kinase II gene family to cattle chromosomes. 61 54
9172313 1997
2
Casein kinase II in theileriosis. 54 61
7846527 1995
3
Effects of Injectable Trace Minerals (ITMs) on Th1/Th2 Cytokine Balance of Newborn Calves with Tropical Theileriosis. 61
32572800 2021
4
Clinical and hematologic features of experimental theileriosis in roan calves (Hippotragus equinus). 61
33450579 2021
5
Endemic infection of cattle with multiple genotypes of Theileria orientalis on the Northern Tablelands of New South Wales despite limited presence of ticks. 61
33388554 2021
6
Molecular epidemiology of Theileria annulata infection of cattle in Layyah District, Pakistan. 61
33599889 2021
7
Knowledge, attitude and perception of bovine piroplasmosis by cattle owners in Constantine, North-East of Algeria, using participatory epidemiology. 61
33594496 2021
8
Interaction between transforming Theileria parasites and their host bovine leukocytes. 61
33565178 2021
9
Serological Survey and Molecular Characterization of Theileria annulata in Sicilian Cattle. 61
33494377 2021
10
A report on tick burden and molecular detection of tick-borne pathogens in cattle blood samples collected from four regions in Saudi Arabia. 61
33465662 2021
11
Contrasting population genetics of co-endemic cattle- and buffalo- derived Theileria annulata. 61
33113478 2021
12
Ticks and Tick-Borne Diseases of Livestock in the Middle East and North Africa: A Review. 61
33477991 2021
13
Novel tumour suppressor roles for GZMA and RASGRP1 in Theileria annulata-transformed macrophages and human B lymphoma cells. 61
32830401 2020
14
Hit identification against peptidyl-prolyl isomerase of Theileria annulata by combined virtual high-throughput screening and molecular dynamics simulation approach. 61
33059132 2020
15
Imidocarb Dipropionate Lacks Efficacy against Theileria haneyi and Fails to Consistently Clear Theileria equi in Horses Co-Infected with T. haneyi. 61
33321715 2020
16
Targeted Next-Generation Sequencing and Informatics as an Effective Tool to Establish the Composition of Bovine Piroplasm Populations in Endemic Regions. 61
33374586 2020
17
Bovine piroplasmosis-anaplasmosis and clinical signs of tropical theileriosis in the plains of Djurdjura (north Algeria). 61
32558239 2020
18
Role of cytokines in the clinical manifestation of exophthalmia in newborn calves with tropical theileriosis. 61
32497247 2020
19
Determining Theileria annulata parasitemia through qPCR in lactating cows of Odisha, - a theileriosis-endemic region of India. 61
33026945 2020
20
Clinical and Pathological Studies on Cattle Experimentally Infected with Theileria annulata in China. 61
32899387 2020
21
Rapid diagnosis of Theileria annulata by colorimetric loop-mediated isothermal amplification (LAMP) assay. 61
32947234 2020
22
First reports of indigenous lethal infection with Anaplasma marginale, Anaplasma bovis and Theileria orientalis in Croatian cattle. 61
32723641 2020
23
Molecular Analysis and Risk Factors Associated With Theileria equi Infection in Domestic Donkeys and Mules of Punjab, Pakistan. 61
32797787 2020
24
Coexistence of Multiple Theileria annulata Genotypes Circulating in Neonatal Calves in Semi-arid India. 61
32319037 2020
25
Molecular Detection and Assessment of Risk Factors for Tick-Borne Diseases in Sheep and Goats from Turkey. 61
32378157 2020
26
Theileria orientalis Ikeda in host-seeking Haemaphysalis longicornis in Virginia, U.S.A. 61
32723633 2020
27
Genetic Diversity of Bovine Hemoprotozoa in South Korea. 61
32962267 2020
28
End Point Multiplex PCR for Diagnosis of Haemoprotozoan Diseases in Cattle. 61
32757111 2020
29
Detection of Theileria spp. in ticks, sheep keds (Melophagus ovinus), and livestock in the eastern Tibetan Plateau, China. 61
32556503 2020
30
Prevalence of ticks (Acari: Ixodidae) and Theileria annulata infection of cattle in Gezira State, Sudan. 61
32420464 2020
31
Clinical Pathology, Immunopathology and Advanced Vaccine Technology in Bovine Theileriosis: A Review. 61
32854179 2020
32
Factors associated with the prevalence of antibodies against Theileria equi in equids of Western Pará, Brazil. 61
31286674 2020
33
Detection and Molecular Characterization of Babesia canis vogeli and Theileria annulata in Free-Ranging Dogs and Ticks from Shahriar County, Tehran Province, Iran. 61
33082796 2020
34
Molecular detection of Theileria spp. and Babesia ovis Infection in Sheep in Baneh, Iran. 61
32621459 2020
35
A Targeted "Next-Generation" Sequencing-Informatic Approach to Define Genetic Diversity in Theileria orientalis Populations within Individual Cattle: Proof-of-Principle. 61
32517045 2020
36
The efficacy of toltrazuril treatment for reducing the infection intensity of Theileria orientalis Ikeda type in dairy calves. 61
32442844 2020
37
Alterations of cardiac and renal biomarkers in horses naturally infected with theileria equi. 61
32505763 2020
38
Equid infective Theileria cluster in distinct 18S rRNA gene clades comprising multiple taxa with unusually broad mammalian host ranges. 61
32430015 2020
39
Molecular detection of small ruminant piroplasmosis and first report of Theileria luwenshuni (Apicomplexa: Theileridae) in small ruminants of Pakistan. 61
32165145 2020
40
DNA of Theileria orientalis, T. equi and T. capreoli in stable flies (Stomoxys calcitrans). 61
32272968 2020
41
Development and application of a multiplex TaqMan® real-time qPCR assay for the simultaneous detection of Anaplasma marginale and Theileria annulata and molecular characterization of Anaplasma marginale from cattle in Western Cuba. 61
31870635 2020
42
Serum-free in vitro cultivation of Theileria annulata and Theileria parva schizont-infected lymphocytes. 61
32174041 2020
43
The protection afforded to cattle immunized with Theileria annulata infected cell line is enhanced by subunit vaccine candidate TaSP. 61
32174037 2020
44
Current status of tropical theileriosis in Northern Africa: A review of recent epidemiological investigations and implications for control. 61
32174036 2020
45
Development and evaluation of a chemiluminescence immunoassay for detecting tropical theileriosis. 61
31676457 2020
46
Haemoparasitic Infections in Cattle from a Trypanosoma brucei Rhodesiense Sleeping Sickness Endemic District of Eastern Uganda. 61
32046044 2020
47
Shape mediated splenotropic delivery of buparvaquone loaded solid lipid nanoparticles. 61
31468307 2020
48
Predicting the potential distribution of Amblyomma americanum (Acari: Ixodidae) infestation in New Zealand, using maximum entropy-based ecological niche modelling. 61
31965414 2020
49
Rapid detection and differentiation of Theileria annulata, T. orientalis and T. sinensis using high-resolution melting analysis. 61
31645296 2020
50
Extracellular vesicles in infectious diseases caused by protozoan parasites in buffaloes. 61
32528536 2020

Variations for Theileriasis

Expression for Theileriasis

Search GEO for disease gene expression data for Theileriasis.

Pathways for Theileriasis

Pathways related to Theileriasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 TNF TLR10 TGFB2 CSNK2A2
2 11.5 TNF TGFB2 JUN
3 11.4 TNF TGFB2 JUN
4
Show member pathways
11.21 TNF TLR10 JUN
5 11.03 TNF TGFB2 SIRPA JUN
6 10.78 TNF MAP4K4 JUN

GO Terms for Theileriasis

Biological processes related to Theileriasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of neuron apoptotic process GO:0043525 9.33 TNF TGFB2 JUN
2 embryonic digestive tract development GO:0048566 9.26 TNF TGFB2
3 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.13 TNF TGFB2 JUN
4 negative regulation of alkaline phosphatase activity GO:0010693 8.62 TNF TGFB2

Sources for Theileriasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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