MCID: THL003
MIFTS: 20

Thelaziasis

Categories: Infectious diseases

Aliases & Classifications for Thelaziasis

MalaCards integrated aliases for Thelaziasis:

Name: Thelaziasis 12 15
Infection by Thelazia 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0050261
UMLS 71 C0344058

Summaries for Thelaziasis

Disease Ontology : 12 A parasitic helminthiasis infectious diseasea that involves infection of the eyes in humans by nematode Thelazia callipaeda causing varying degrees of inflammation and lacrimation. In heavier infections, photophobia, edema, conjunctivitis, and blindness occurs.

MalaCards based summary : Thelaziasis, also known as infection by thelazia, is related to conjunctivitis and retinal detachment. An important gene associated with Thelaziasis is MT-TY (Mitochondrially Encoded TRNA-Tyr (UAU/C)), and among its related pathways/superpathways is tRNA Aminoacylation. Affiliated tissues include eye.

Wikipedia : 74 Thelaziasis is the term for infestation with parasitic nematodes of the genus Thelazia. The adults of... more...

Related Diseases for Thelaziasis

Diseases related to Thelaziasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
# Related Disease Score Top Affiliating Genes
1 conjunctivitis 10.5
2 retinal detachment 10.3
3 filariasis 10.2
4 allergic conjunctivitis 10.2
5 corneal abscess 10.2
6 eye disease 10.2
7 cataract 10.2
8 intestinal impaction 10.1 MT-TY MT-TN
9 mitochondrial dna-related progressive external ophthalmoplegia 9.9 MT-TN MT-TL2
10 hereditary optic neuropathy 9.9 MT-ND6 MT-ND4L
11 trench fever 9.9 MT-TN MT-TL2
12 cranial nerve disease 9.8 MT-ND6 MT-ND4L
13 gnathomiasis 9.8 MT-TY MT-CO1
14 coenurosis 9.8 MT-TY MT-CO1
15 chronic progressive external ophthalmoplegia 9.8 MT-TL2 MT-ND6
16 pthirus pubis infestation 9.7 MT-TY MT-CO1
17 lice infestation 9.7 MT-TY MT-CO1
18 parasitic ectoparasitic infectious disease 9.7 MT-TY MT-CO1
19 mitochondrial disorders 9.7 MT-TL2 MT-ND6
20 familial colorectal cancer 9.6 MT-ND4L MT-CO1
21 optic nerve disease 9.6 MT-ND6 MT-ND4L
22 mitochondrial complex iv deficiency 9.5 MT-TN MT-CO1
23 mitochondrial complex i deficiency, nuclear type 1 9.5 MT-ND6 MT-ND4L
24 lactic acidosis 9.3 MT-TL2 MT-ND6 MT-CO1
25 leigh syndrome 9.2 MT-ND6 MT-ND4L MT-CO1
26 mitochondrial myopathy 8.9 MT-TL2 MT-ND6 MT-ND4L MT-CO1
27 mitochondrial encephalomyopathy 8.9 MT-TL2 MT-ND6 MT-ND4L MT-CO1
28 leber optic atrophy 8.9 MT-TL2 MT-ND6 MT-ND4L MT-CO1
29 mitochondrial metabolism disease 8.8 MT-TL2 MT-ND6 MT-ND4L MT-CO1
30 kearns-sayre syndrome 8.6 MT-TY MT-TL2 MT-ND6 MT-ND4L MT-CO1
31 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 8.5 MT-TN MT-TL2 MT-ND6 MT-ND4L MT-CO1

Graphical network of the top 20 diseases related to Thelaziasis:



Diseases related to Thelaziasis

Symptoms & Phenotypes for Thelaziasis

Drugs & Therapeutics for Thelaziasis

Search Clinical Trials , NIH Clinical Center for Thelaziasis

Genetic Tests for Thelaziasis

Anatomical Context for Thelaziasis

MalaCards organs/tissues related to Thelaziasis:

40
Eye

Publications for Thelaziasis

Articles related to Thelaziasis:

(show top 50) (show all 76)
# Title Authors PMID Year
1
Periocular thelaziasis presenting as an orbital mass - a case report. 61
30668201 2019
2
First report of eyeworm infection by Thelazia callipaeda in gray wolf (Canis lupus) from Serbia. 61
31722066 2019
3
[Advances in etiology, epidemiology and genetic diversity of Thelazia callipaeda]. 61
31016929 2019
4
Human ocular thelaziasis caused by gravid Thelazia callipaeda - A unique and rare case report. 61
30672496 2019
5
[Human thelaziasis callipaeda in Tongren area of Guizhou Province: a case report]. 61
31184066 2018
6
Human Thelaziasis: Emerging Ocular Pathogen in Nepal. 61
30349847 2018
7
Live encysted Thelazia callipaeda presenting as a lump adjacent to the right lacrimal sac in a 42-year-old female: A rare case report. 61
30038190 2018
8
Ocular thelaziasis: A case report from Assam, India. 61
30693214 2018
9
Case Report: Conjunctival Infestation with Thelazia gulosa: A Novel Agent of Human Thelaziasis in the United States. 61
29436343 2018
10
Population structure analysis of the neglected parasite Thelazia callipaeda revealed high genetic diversity in Eastern Asia isolates. 61
29324738 2018
11
Thelazia callipaeda infection in a 5-month-old infant. 61
28710682 2017
12
[Genetic variation of Thelazia callipaeda among isolates collected from patients in Zunyi City, Guizhou Province]. 61
29469356 2017
13
Morphological and Mitochondrial Genomic Characterization of Eyeworms (Thelazia callipaeda) from Clinical Cases in Central China. 61
28751889 2017
14
A Pediatric Case of Thelaziasis in Korea. 61
27417087 2016
15
Human ocular thelaziasis: a case report from Karnataka. 61
25866001 2015
16
Human ocular thelaziasis in Karnataka. 61
25827555 2015
17
[THE FIRST CASE OF OCULAR THELAZIASIS IN CROATIA]. 61
29087095 2015
18
Two cases of human thelaziasis as confirmed by mitochondrial cox1 sequencing in China. 61
25253041 2014
19
Human ocular thelaziasis in Karnataka. 61
25116781 2014
20
Parasitic infections based on 320 clinical samples submitted to Hanyang University, Korea (2004-2011). 61
24850969 2014
21
Ocular thelaziasis in a 7-month-old infant. 61
24399399 2014
22
Thelazia callipaeda: a human case report. 61
23077806 2012
23
Two cases of human thelaziasis and brief review of Korean cases. 61
22072826 2011
24
Thelazia rhodesii in the African buffalo, Syncerus caffer, in Zambia. 61
21461276 2011
25
Zoonotic helminths affecting the human eye. 61
21429191 2011
26
Human thelaziasis in Bangladesh. 61
21240176 2011
27
Ocular thelaziosis in dogs, France. 61
21122226 2010
28
A case of intraocular thelaziasis with rhegmatogenous retinal detachment. 61
20629668 2010
29
[Two cases of thelaziasis]. 61
21137311 2010
30
Analysis of parasitic diseases diagnosed by tissue biopsy specimens at KyungHee Medical Center (1984-2005) in Seoul, Korea. 61
20333293 2010
31
Human thelaziasis, Europe. 61
18394285 2008
32
[Ocular thelaziasis in man in Northern Italy]. 61
18431997 2008
33
Ocular thelaziasis in Assam: a report of two cases. 61
18417889 2008
34
First reports of autochthonous eyeworm infection by Thelazia callipaeda (Spirurida, Thelaziidae) in dogs and cat from France. 61
17854998 2007
35
Morphological differentiation among three Thelazia species (Nematoda: Thelaziidae) by scanning electron microscopy. 61
17211660 2007
36
Human thelaziasis in India. 61
17377361 2007
37
Human Thelaziasis occurrence in Taiwan. 61
16430440 2006
38
A case of human thelaziasis from Himachal Pradesh. 61
16505563 2006
39
[Longitudinal investigation and experimental studies on thelaziasis and the intermediate host of Thelazia callipaeda in Guanghua county of Hubei province]. 61
12975015 2003
40
Five cases of thelaziasis. 61
10777285 2000
41
Two human cases of Thelazia callipaeda infection in Korea. 61
7551806 1995
42
Thelaziasis: report of two cases. 61
8025054 1993
43
[Parasitic zoonoses in Japan, with special reference to the current topics]. 61
2513435 1989
44
Scanning electron microscopic observations of Thelazia callipaeda from human. 61
2486933 1989
45
Ocular thelaziasis in Thailand: a case report. 61
2809450 1989
46
First case of human Thelaziasis in Indonesia. 61
2609214 1989
47
A human case of Thelazia callipaeda infection with reference to its internal structures. 61
12811061 1988
48
[A case of human thelaziasis occurred in both eyes] 61
12811060 1988
49
[A case of ocular thelaziasis in a 3-year-old child]. 61
3394210 1988
50
A case of human thelaziasis in Korea. 61
12886085 1987

Variations for Thelaziasis

Expression for Thelaziasis

Search GEO for disease gene expression data for Thelaziasis.

Pathways for Thelaziasis

Pathways related to Thelaziasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.04 MT-TY MT-TN MT-TL2

GO Terms for Thelaziasis

Cellular components related to Thelaziasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial membrane GO:0031966 8.96 MT-ND6 MT-ND4L
2 respiratory chain GO:0070469 8.8 MT-ND6 MT-ND4L MT-CO1

Biological processes related to Thelaziasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.13 MT-ND6 MT-ND4L MT-CO1
2 mitochondrial electron transport, NADH to ubiquinone GO:0006120 8.62 MT-ND6 MT-ND4L

Molecular functions related to Thelaziasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADH dehydrogenase (ubiquinone) activity GO:0008137 8.62 MT-ND6 MT-ND4L

Sources for Thelaziasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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