MCID: THR106
MIFTS: 11

Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

MalaCards integrated aliases for Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome:

Name: Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome 52

Classifications:



Summaries for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

MalaCards based summary : Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome is related to leukemia, acute myeloid and myelodysplastic syndrome. The drugs Gedatolisib and Protein Kinase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include myeloid and breast.

Related Diseases for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Diseases related to Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 12, show less)
# Related Disease Score Top Affiliating Genes
1 leukemia, acute myeloid 12.2
2 myelodysplastic syndrome 10.7
3 myeloid leukemia 10.7
4 germ cells tumors 10.4
5 lymphoma, hodgkin, classic 10.1
6 leukemia, acute lymphoblastic 10.1
7 lymphoma 10.1
8 lymphocytic leukemia 10.1
9 pancytopenia 10.1
10 acute leukemia 10.1
11 extragonadal germ cell cancer 10.1
12 refractory anemia with excess blasts in transformation 10.1

Graphical network of the top 20 diseases related to Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome:



Diseases related to Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome

Symptoms & Phenotypes for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Drugs & Therapeutics for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Drugs for Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 2, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Gedatolisib Investigational Phase 2 1197160-78-3
2 Protein Kinase Inhibitors Phase 2

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Phase II Evaluating the Efficacy of the Dual Inhibition of Phosphoinositide 3 Kinase (PI3K)/Akt /Mammalian Target Of Rapamycine (mTOR) Signaling Pathway by PF-05212384 (PKI-587) for Patients With Myeloid Neoplasm Secondary to Chemo-radiotherapy (t-AML/MDS) or de Novo Relapsed or Refractory AML. Terminated NCT02438761 Phase 2 PF-05212384

Search NIH Clinical Center for Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome

Genetic Tests for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Anatomical Context for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

MalaCards organs/tissues related to Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome:

40
Myeloid, Breast

Publications for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Articles related to Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome:

(showing 14, show less)
# Title Authors PMID Year
1
Clinicopathological aspects of therapy-related acute myeloid leukemia and myelodysplastic syndrome. 61
30927972 2019
2
Re: Therapy-related acute myeloid leukemia and myelodysplastic syndrome among refractory germ cell tumor patients. 61
30269361 2018
3
Editorial Comment to Therapy-related acute myeloid leukemia and myelodysplastic syndrome among refractory germ cell tumor patients. 61
29869384 2018
4
Therapy-related acute myeloid leukemia and myelodysplastic syndrome among refractory germ cell tumor patients. 61
29752743 2018
5
Therapy-related acute myeloid leukemia and myelodysplastic syndrome after hematopoietic cell transplantation for lymphoma. 61
28368379 2017
6
Chronic Myeloid Leukemia Developing After Successful Treatment of Acute Promyelocytic Leukemia. 61
27408368 2016
7
High p53 protein expression in therapy-related myeloid neoplasms is associated with adverse karyotype and poor outcome. 61
25412846 2015
8
Autologous stem cell transplantation for therapy-related acute myeloid leukemia and myelodysplastic syndrome. 61
17322936 2007
9
Autologous stem cell transplantation for therapy-related acute myeloid leukemia and myelodysplastic syndrome. 61
16299545 2006
10
Genetic polymorphisms in CYP3A5, CYP3A4 and NQO1 in children who developed therapy-related myeloid malignancies. 61
12439220 2002
11
Myeloid malignancies induced by alkylating agents in Nf1 mice. 61
10339466 1999
12
Therapy-related leukemia and myelodysplasia following oral administration of etoposide for recurrent breast cancer. 61
9625808 1998
13
The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1. 61
8395054 1993
14
Therapy-related acute myeloid leukemia and myelodysplastic syndrome: a clinical and morphologic study of 65 cases. 61
3857944 1985

Variations for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Expression for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Search GEO for disease gene expression data for Therapy Related Acute Myeloid Leukemia and Myelodysplastic Syndrome.

Pathways for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

GO Terms for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

Sources for Therapy Related Acute Myeloid Leukemia and Myelodysplastic...

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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