MCID: THR099
MIFTS: 42

Third-Degree Atrioventricular Block

Categories: Cardiovascular diseases

Aliases & Classifications for Third-Degree Atrioventricular Block

MalaCards integrated aliases for Third-Degree Atrioventricular Block:

Name: Third-Degree Atrioventricular Block 12 15
Complete Atrioventricular Block 74
Complete Av Block 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050823
ICD10 34 I44.2
UMLS 74 C0151517

Summaries for Third-Degree Atrioventricular Block

Disease Ontology : 12 An atrioventricular block that is characterized by bradycardia, hypotension, hemodynamic instability and complete dissociation between P waves and QRS complexes on electrocardiogram caused when conduction fails to propagate from atria to ventricles.

MalaCards based summary : Third-Degree Atrioventricular Block, also known as complete atrioventricular block, is related to atrioventricular block and syncope. An important gene associated with Third-Degree Atrioventricular Block is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways are Phase 0 - rapid depolarisation and Antiarrhythmic Pathway, Pharmacodynamics. The drugs Levofloxacin and Ethinyl Estradiol have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and atrioventricular node.

Wikipedia : 77 Third-degree atrioventricular block (AV block), also known as complete heart block, is a medical... more...

Related Diseases for Third-Degree Atrioventricular Block

Diseases related to Third-Degree Atrioventricular Block via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 atrioventricular block 30.6 HCN4 KCNE2 NPPB SCN5A
2 syncope 30.5 NPPB SCN5A
3 cardiac arrest 29.6 NPPB SCN5A
4 atrial fibrillation 29.4 HCN4 KCNE2 NPPB SCN5A
5 long qt syndrome 29.3 HCN4 KCNE2 SCN5A
6 heart disease 28.9 HCN4 KCNE2 NPPB SCN5A
7 myocardial infarction 10.4
8 neuropathy, hereditary sensory and autonomic, type iii 10.2
9 second-degree atrioventricular block 10.2
10 myocarditis 10.2
11 dysautonomia 10.2
12 first-degree atrioventricular block 10.1 DSG4 SCN5A
13 left bundle branch hemiblock 10.1 NPPB SCN5A
14 progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1 10.1
15 myositis 10.1
16 pheochromocytoma 10.1
17 myasthenia gravis 10.1
18 nasopharyngeal carcinoma 10.1
19 progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 2 10.1
20 progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 3 10.1
21 progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 4 10.1
22 acute myocardial infarction 10.1
23 congestive heart failure 10.1
24 diabetes mellitus 10.1
25 paraganglioma 10.1
26 fibroma 10.1
27 adrenal gland pheochromocytoma 10.1
28 lymphoma 10.1
29 endocarditis 10.1
30 cardiac tamponade 10.1
31 chagas disease 10.1
32 graves' disease 10.1
33 chronic progressive external ophthalmoplegia 10.1
34 melanoma 10.1
35 acute myocarditis 10.1
36 inferior myocardial infarction 10.1
37 retinal degeneration 10.1
38 pulmonary embolism 10.1
39 rere-related disorders 10.1
40 baroreflex failure 10.1
41 bronchogenic cyst 10.1
42 myasthenia gravis congenital 10.1
43 ocular muscular dystrophy 10.1
44 pure autonomic failure 10.1
45 cardiogenic shock 10.1
46 schizoaffective disorder 10.1
47 familial sick sinus syndrome 10.1 HCN4 SCN5A
48 sick sinus syndrome 10.0 HCN4 SCN5A
49 long qt syndrome 9 10.0 HCN4 SCN5A
50 right bundle branch block 10.0 HCN4 SCN5A

Comorbidity relations with Third-Degree Atrioventricular Block via Phenotypic Disease Network (PDN): (show all 30)


Acute Cystitis Acute Kidney Failure
Aortic Valve Disease 1 Atrioventricular Block
Cardiac Arrest Cardiogenic Shock
Chronic Kidney Failure Chronic Myocardial Ischemia
Deficiency Anemia Dressler's Syndrome
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Hypothyroidism
Intermediate Coronary Syndrome Ischemic Heart Disease
Kidney Disease Mitral Valve Disease
Mobitz Type Ii Atrioventricular Block Monocular Esotropia
Peripheral Vascular Disease Progressive Familial Heart Block, Type Ia
Pulmonary Hypertension, Primary, 1 Respiratory Failure
Right Bundle Branch Block Sinoatrial Node Disease
Tricuspid Valve Disease Ventricular Fibrillation, Paroxysmal Familial, 1

Graphical network of the top 20 diseases related to Third-Degree Atrioventricular Block:



Diseases related to Third-Degree Atrioventricular Block

Symptoms & Phenotypes for Third-Degree Atrioventricular Block

Drugs & Therapeutics for Third-Degree Atrioventricular Block

Drugs for Third-Degree Atrioventricular Block (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 150)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
2
Ethinyl Estradiol Approved Phase 4,Phase 1 57-63-6 5991
3
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
4
Polyestradiol phosphate Approved Phase 4,Phase 1 28014-46-2
5
Norgestimate Approved, Investigational Phase 4,Phase 1 35189-28-7 6540478
6
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 1 50-28-2 5757
7
Moxifloxacin Approved, Investigational Phase 4,Phase 1 354812-41-2, 151096-09-2 152946
8 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 1
9 Estradiol 3-benzoate Phase 4,Phase 1
10 Contraceptives, Oral, Combined Phase 4,Phase 1
11 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Contraceptive Agents Phase 4,Phase 1
13 Contraceptives, Oral Phase 4,Phase 1
14 Anti-Infective Agents, Urinary Phase 4,Phase 3
15 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 1
16 Renal Agents Phase 4,Phase 3
17 Estradiol 17 beta-cypionate Phase 4,Phase 1
18 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1
19 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3
20 Norgestimate, ethinyl estradiol drug combination Phase 4,Phase 1
21
Adenosine Approved, Investigational Phase 3,Phase 2 58-61-7 60961
22
Dopamine Approved Phase 3 62-31-7, 51-61-6 681
23
Aripiprazole Approved, Investigational Phase 3 129722-12-9 60795
24
rituximab Approved Phase 3 174722-31-7 10201696
25
Regadenoson Approved, Investigational Phase 3 313348-27-5 219024
26
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
27
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
28
Bacitracin Approved, Vet_approved Phase 3 1405-87-4 10909430 439542
29
Cephalexin Approved, Investigational, Vet_approved Phase 3 15686-71-2 27447
30
Polymyxin B Approved, Vet_approved Phase 3 1404-26-8
31
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
32
leucovorin Approved Phase 3 58-05-9 143 6006
33
Digoxin Approved Phase 3 20830-75-5 2724385 30322
34
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
35
Binodenoson Investigational Phase 3 144348-08-3
36 Anti-Arrhythmia Agents Phase 3,Phase 1
37 Peripheral Nervous System Agents Phase 3,Phase 1
38 Neurotransmitter Agents Phase 3,Phase 2
39 Cardiotonic Agents Phase 3
40 Protective Agents Phase 3
41 Analgesics Phase 3,Phase 1
42 Vasodilator Agents Phase 3,Phase 1
43 Antipsychotic Agents Phase 3
44 Dopamine Agents Phase 3
45 Psychotropic Drugs Phase 3
46 Serotonin Agents Phase 3
47 Serotonin Antagonists Phase 3
48 Dopamine D2 Receptor Antagonists Phase 3
49 Serotonin 5-HT1 Receptor Agonists Phase 3
50 Antidepressive Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 70)
# Name Status NCT ID Phase Drugs
1 Assessment of the Prognosis of Persistent Left Bundle Branch Block (LBBB)After Transcatheter Aortic Valve Implantation (TAVI ) by an Electrophysiological and Remote Monitoring Risk-adapted Algorithm Unknown status NCT02482844 Phase 4
2 Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function Unknown status NCT02509754 Phase 4
3 Mode Evaluation in Sick Sinus Syndrome Trial (MODEST) Unknown status NCT00161551 Phase 4
4 Syncope: Pacing or Recording in the Later Years Completed NCT01423994 Phase 4
5 Catheter Evaluation for Endocardial Ablation in Patients With Typical Atrial Flutter Completed NCT00318565 Phase 4
6 Avelox for Treatment of Elderly Patients With Community Acquired Pneumonia Completed NCT00665327 Phase 4 Avelox (Moxifloxacin, BAY12-8039);Levofloxacin
7 Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal Defect Unknown status NCT02644330 Phase 2, Phase 3
8 First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study) Unknown status NCT00392054 Phase 3 Conventional Antiarrhythmic Drug Therapy
9 Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia Completed NCT00944970 Phase 3 binodenoson;adenosine
10 Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia Completed NCT00944294 Phase 3 binodenoson;adenosine
11 Aripiprazole for Schizophrenia Outpatients Completing BMS Clinical Trials Completed NCT00239356 Phase 3 Aripiprazole
12 Study to Assess the Effect of Treatment With Bendamustine in Combination With Rituximab on QT Interval in Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL) Completed NCT01073163 Phase 3 Bendamustine;Rituximab
13 A Study to Assess Regadenoson Administration Following an Inadequate Exercise Stress Test as Compared to Regadenoson Alone for Myocardial Perfusion Imaging (MPI) Using Single Photon Emission Computed Tomography (SPECT) Completed NCT01618669 Phase 3 Regadenoson
14 Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections. Recruiting NCT02809131 Phase 3 polymixin/bacitracin;cephalexin, or levofloxacin, or clindamycin;Saline
15 Cardiac Sarcoidosis Randomized Trial Recruiting NCT03593759 Phase 3 Prednisone;Methotrexate
16 Digoxin Short Term Treatment Assessment Randomized Trial in AHF Recruiting NCT02544815 Phase 3 Digoxin;Placebo
17 Combretastatin A4 Phosphate in Patients With Neovascular Age-Related Macular Degeneration Completed NCT01570790 Phase 1, Phase 2 Combretastatin A-4 phosphate;Combretastatin A-4 Phosphate;Combretastatin A-4 Phosphate
18 The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy Completed NCT00694161 Phase 2 Fx-1006A
19 Study to Investigate the Effects of Orteronel on the QT/QTc Interval in Patients With Metastatic Castration-Resistant Prostate Cancer Completed NCT01549951 Phase 2 Orteronel+Prednisone
20 Multiple Dose Study in Heart Failure of BAY 1067197 Completed NCT02040233 Phase 2 BAY1067197 (10 mg);BAY1067197;Placebo (10 mg);Placebo
21 Preventive Approach to Congenital Heart Block With Hydroxychloroquine Recruiting NCT01379573 Phase 2 Hydroxychloroquine
22 Trial of Topical Verapamil in Chronic Rhinosinusitis With Nasal Polyps Completed NCT03102190 Phase 1 Verapamil Hydrochloride Intranasal
23 The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy Volunteers Completed NCT01999114 Phase 1 Buprenorphine transdermal patch;Naltrexone tablet;Placebos (for TDS and for naltrexone and for moxifloxacin);Moxifloxacin tablet
24 Study Assessing the Effects of Darunavir/Ritonavir or Lopinavir/Ritonavir on the Pharmacokinetics of Daclatasvir in Healthy Participants Completed NCT02159352 Phase 1 Daclatasvir;Darunavir;Ritonavir;Lopinavir/Ritonavir
25 Trial to Evaluate the Effects of OPC-34712 on QT/QTc in Subjects With Schizophrenia or Schizoaffective Disorder Completed NCT01423916 Phase 1 OPC-34712 (4mg);Moxifloxacin;OPC-34712 (12mg);Placebo
26 Study to Assess the Effect of Macitentan on the Electrocardiogram (ECG) in Healthy Male and Female Subjects Completed NCT02050802 Phase 1 Moxifloxacin 400 mg;Macitentan 10 mg;Macitentan 30 mg
27 Identification of Genetic Basis of Atrioventricular Conduction Defects: From Congenital Forms to Degenerative Forms Unknown status NCT02881671
28 Effects of Chronic Right Ventricular Pacing in Children With Advanced Atrioventricular Block Unknown status NCT01477658
29 HV Electrophysiology Study In Transcatheter Aortic Valve Implantation Patients Unknown status NCT02659137
30 Prognostic Accuracy of Coronary CT and Dobutamine Stress Echocardiography in Patient Undergoing Non-cardiac Surgery Unknown status NCT02250963
31 Exercise in Chronically Paced Children Completed NCT00374608
32 Electrophysiologic HV-interval as a Predicor for Permanent Pacemaker Implantation After TAVI Completed NCT01801098
33 Preventive IVIG Therapy for Congenital Heart Block Completed NCT00460928 Early Phase 1 intravenous immune globulin (IVIG)
34 PROTECT-PACE STUDY - The Protection of Left Ventricular Function During Right Ventricular Pacing Completed NCT00461734 Not Applicable
35 Echocardiography Predictive of the Inefficacy and/or of the Unsafeness of Recruitment Maneuvers in Patients With Acute Respiratory Distress Syndrome. Completed NCT01768949 Not Applicable
36 Medtronic CoreValve REDO Study Completed NCT01051310 Not Applicable
37 Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures Completed NCT00771927 Lacosamide
38 Plasma Glucagon-like Peptide-1 Levels and In-hospital Complications in ST-segment Elevation Myocardial Infarction Completed NCT03314844
39 Early Postoperative Blood Glucose Variability and Outcome After TAVI Completed NCT02726958
40 Association Between Plasma Melatonin and No-reflow Completed NCT03306303
41 Plasma Dipeptidyl-peptidase-4 Activities With No-reflow and Bleeding Completed NCT02849691
42 Indication of Permanent Cardiac Parcing After Tanscatheter Aortic Valve Implantation Completed NCT02337140 Not Applicable
43 HAART 200 Aortic Valve Annuloplasty Trial Completed NCT02071849 Not Applicable
44 HAART Model 300 Annuloplasty Ring Completed NCT01400841 Not Applicable
45 The HAART 300 Annuloplasty Ring Trial Extended Safety and Performance Completed NCT01732835 Not Applicable
46 Evaluation of Atrial Fibrillation Occurrence in Sick Sinus and Complete Atrioventricular Block Patients After Pacemaker Implantation (AF-pacemaker Study) Recruiting NCT03303872
47 Microfidelity (MIFI) Ablation Technology Versus Standard Ablation Catheter for Atrioventricular Nodal Ablation Recruiting NCT03114124 Not Applicable
48 Left Ventricular Pacing to Avoid Cardiac Enlargement Study Recruiting NCT01302717 Not Applicable
49 Ambulatory Electrocardiographic Monitoring for the Detection of High-Degree Atrio-Ventricular Block in Patients With New-onset PeRsistent LEft Bundle Branch Block After Transcatheter Aortic Valve Implantation. The "MARE" Study Recruiting NCT02153307 Not Applicable
50 Assessment of Arrhythmias in Patients Undergoing Transcatheter Aortic Valve Implantation Using a Small Insertable Cardiac Monitoring Device Recruiting NCT02559011

Search NIH Clinical Center for Third-Degree Atrioventricular Block

Genetic Tests for Third-Degree Atrioventricular Block

Anatomical Context for Third-Degree Atrioventricular Block

MalaCards organs/tissues related to Third-Degree Atrioventricular Block:

42
Heart, Testes, Atrioventricular Node, B Cells, Brain, Adrenal Gland, Retina

Publications for Third-Degree Atrioventricular Block

Articles related to Third-Degree Atrioventricular Block:

(show top 50) (show all 633)
# Title Authors Year
1
Rescue Percutaneous Coronary Intervention for a Lethal "Jailed" Septal Perforator Branch to Resolve Delayed Complete Atrioventricular Block. ( 30799381 )
2019
2
His-bundle pacing in a patient with dextrocardia, severe systolic dysfunction, and complete atrioventricular block. ( 30891412 )
2019
3
Cardiac Magnetic Resonance Identified the Fibrotic Lesion Associated with Syncope Attack Due to Complete Atrioventricular Block in a Patient with Hypertrophic Cardiomyopathy and Aortic Stenosis. ( 30918200 )
2019
4
A Unique Case of Complete Atrioventricular Block Rapidly Progressing to Diastolic and Systolic Dysfunction in Cardiac Sarcoidosis. ( 30956665 )
2019
5
Complete atrioventricular block during exercise: New insights from an old test. ( 30968667 )
2019
6
Causes of fetal third-degree atrioventricular block and use of hydroxychloroquine in pregnant women with Ro/La antibodies. ( 30997589 )
2019
7
Predicting postpartum cardiac events in pregnant women with complete atrioventricular block. ( 31060956 )
2019
8
A rat model of complete atrioventricular block recapitulates clinical indices of bradycardia and provides a platform to test disease-modifying therapies. ( 31061413 )
2019
9
Post-pacemaker implant QRS duration and heart failure admission in patients with sick sinus syndrome and complete atrioventricular block. ( 31111655 )
2019
10
Maternal steroid therapy for fetuses with immune-mediated complete atrioventricular block: a systematic review and meta-analysis. ( 29251180 )
2019
11
Interventricular septum involvement with complete atrioventricular block as first manifestation in Takayasu arteritis. ( 29340988 )
2019
12
Complete Atrioventricular Block Associated with Pembrolizumab-induced Acute Myocarditis: The Need for Close Cardiac Monitoring. ( 29877257 )
2018
13
Unexpected delayed complete atrioventricular block after Cardioband implantation. ( 29508515 )
2018
14
Paroxysmal complete atrioventricular block in pediatric heart transplant recipients following cardiac catheterization: A case series. ( 29744993 )
2018
15
Importance of Early Diagnosis of Cardiac Sarcoidosis in Patients with Complete Atrioventricular Block. ( 29794391 )
2018
16
Echocardiographic assessment of ventricular contraction and synchrony in children with isolated complete atrioventricular block and epicardial pacing: Implications of interventricular mechanical delay. ( 29808935 )
2018
17
Cardiac pacing for complete atrioventricular block complicating heart lymphoma: A challenging issue. ( 29933920 )
2018
18
Complete Atrioventricular Block in an Elderly Patient Treated with Low-Dose Lacosamide. ( 29948594 )
2018
19
A Case of Congenital Complete Atrioventricular Block Treated with Transdermal Tulobuterol. ( 29955022 )
2018
20
Complete atrioventricular block as an initial manifestation of recurred oral cavity cancer: a case report. ( 29986652 )
2018
21
Frequency of Complete Atrioventricular Block Complicating ST-Elevation Myocardial Infarction in Patients Undergoing Primary Percutaneous Coronary Intervention. ( 30016805 )
2018
22
Third-degree atrioventricular block followed by syncope, labile hypertension, and orthostatic hypotension in a patient with nasopharyngeal cancer: baroreflex failure. ( 30038845 )
2018
23
Association of Anti-Ro/Sjögren's syndrome type A Antibodies and Complete Atrioventricular Block in an Adult With Sjögren's Syndrome. ( 30207577 )
2018
24
Cardiac Sarcoidosis Presenting as Complete Atrioventricular Block: Findings on PET/MRI. ( 30238713 )
2018
25
Late recovery of sinus rhythm following perioperative complete atrioventricular block in a child with congenitally corrected transposition. ( 30271020 )
2018
26
Left ventricular reverse remodeling after transcatheter aortic valve implantation complicated by paroxysmal complete atrioventricular block. ( 30279890 )
2018
27
Late complete atrioventricular block after hybrid perimembranous ventricular septal defect closure in a neonate. ( 30338840 )
2018
28
Histologically confirmed case of complete atrioventricular block due to hepatocellular carcinoma. ( 30366889 )
2018
29
Prognostic Implications of QRS Duration in Third-Degree Atrioventricular Block Patients with Heart Failure Treated with Cardiac Resynchronization Therapy. ( 30369567 )
2018
30
Cardiac Sarcoidosis Mimicking Septal Tumor with Intermittent Complete Atrioventricular Block. ( 30369580 )
2018
31
Syncope due to complete atrioventricular block and treatment with a transient pacemaker in acute rheumatic fever. ( 30459521 )
2018
32
Immunoglobulin G4-related disease of the thickened aortic valve extending to the left ventricular outflow tract causing severe aortic regurgitation and complete atrioventricular block: a case report. ( 31020164 )
2018
33
Complete atrioventricular block in acute coronary syndrome: prevalence, characterisation and implication on outcome. ( 28617040 )
2018
34
Exercise induced complete atrioventricular block: Utility of exercise stress test. ( 29042058 )
2018
35
Predictive markers and prenatal management of isolated fetal complete atrioventricular block: A retrospective review at a single institution. ( 29160028 )
2018
36
Swallow presyncope in an athletic patient caused by third-degree atrioventricular block. ( 29202647 )
2018
37
Sinus node dysfunction masquerading as complete atrioventricular block in the setting of atrial parasystole after heart transplantation. ( 29263012 )
2018
38
An unusual case of complete atrioventricular block causing Takotsubo syndrome. ( 29325979 )
2018
39
An extremely rare clinical entity: congenitally corrected transposition with situs ınversus and single coronary artery presented with complete atrioventricular block in a young man. ( 29428001 )
2018
40
Major determinant of the occurrence of pacing-induced cardiomyopathy in complete atrioventricular block: a multicentre, retrospective analysis over a 15-year period in South Korea. ( 29439074 )
2018
41
Increased healthcare utilization associated with complete atrioventricular block in pacemaker patients. ( 29492807 )
2018
42
Clinical utility of percutaneous coronary intervention on left anterior descending stenosis in the setting of third-degree atrioventricular block due to inferior myocardial infarction: a case report. ( 31020079 )
2018
43
Computed tomography is important in appropriately diagnosing patients with third-degree atrioventricular block and second-degree atrioventricular block but not Wenckebach type. ( 27886613 )
2017
44
New-onset third-degree atrioventricular block because of autoimmune-induced myositis under treatment with anti-programmed cell death-1 (nivolumab) for metastatic melanoma. ( 27977496 )
2017
45
A rare cause of aortic regurgitation and complete atrioventricular block. ( 28017926 )
2017
46
Junctional ectopic tachycardia in late period after early postoperative complete atrioventricular block: Messenger of return to normal sinus rhythm? : Explanation with four case series. ( 28189280 )
2017
47
Third-degree atrioventricular block: tip of the iceberg of a systemic disease. ( 28204445 )
2017
48
Spontaneous Remission of Congenital Complete Atrioventricular Block in Anti-Ro/La Antibody-Negative Monozygotic Twins: Case Report. ( 28251027 )
2017
49
Third-Degree Atrioventricular Block and Collapse Associated with Eosinophilic Myocarditis in a Horse. ( 28295606 )
2017
50
Vagal third-degree atrioventricular block in a highly trained endurance athlete. ( 28430941 )
2017

Variations for Third-Degree Atrioventricular Block

Expression for Third-Degree Atrioventricular Block

Search GEO for disease gene expression data for Third-Degree Atrioventricular Block.

Pathways for Third-Degree Atrioventricular Block

Pathways related to Third-Degree Atrioventricular Block according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.83 KCNE2 SCN5A
2 10.55 HCN4 KCNE2 SCN5A

GO Terms for Third-Degree Atrioventricular Block

Biological processes related to Third-Degree Atrioventricular Block according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 regulation of ion transmembrane transport GO:0034765 9.54 HCN4 KCNE2 SCN5A
2 sodium ion transmembrane transport GO:0035725 9.49 HCN4 SCN5A
3 potassium ion import across plasma membrane GO:1990573 9.48 HCN4 KCNE2
4 regulation of heart rate GO:0002027 9.46 HCN4 SCN5A
5 regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 9.43 KCNE2 SCN5A
6 ventricular cardiac muscle cell action potential GO:0086005 9.4 KCNE2 SCN5A
7 cardiac muscle cell action potential involved in contraction GO:0086002 9.32 KCNE2 SCN5A
8 membrane depolarization during cardiac muscle cell action potential GO:0086012 9.26 HCN4 SCN5A
9 SA node cell action potential GO:0086015 9.16 HCN4 SCN5A
10 membrane depolarization during SA node cell action potential GO:0086046 8.96 HCN4 SCN5A
11 regulation of heart rate by cardiac conduction GO:0086091 8.8 HCN4 KCNE2 SCN5A

Molecular functions related to Third-Degree Atrioventricular Block according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium channel activity GO:0005267 9.32 HCN4 KCNE2
2 voltage-gated potassium channel activity GO:0005249 9.26 HCN4 KCNE2
3 sodium channel activity GO:0005272 9.16 HCN4 SCN5A
4 voltage-gated sodium channel activity GO:0005248 8.96 HCN4 SCN5A
5 voltage-gated ion channel activity GO:0005244 8.8 HCN4 KCNE2 SCN5A

Sources for Third-Degree Atrioventricular Block

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70 SNOMED-CT via HPO
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