MCID: THR013
MIFTS: 50

Thoracic Outlet Syndrome

Categories: Rare diseases, Cardiovascular diseases

Aliases & Classifications for Thoracic Outlet Syndrome

MalaCards integrated aliases for Thoracic Outlet Syndrome:

Name: Thoracic Outlet Syndrome 12 76 54 59 43 44 15 73
Tos 53 59
Thoracic Outlet Compression Syndrome 59
Tos - Thoracic Outlet Syndrome 12
Thoracic Outlet Syndromes 53
Abnormality of Toe 29

Classifications:



External Ids:

Disease Ontology 12 DOID:3103
ICD10 33 G54.0
MeSH 44 D013901
NCIt 50 C85188
Orphanet 59 ORPHA97330
UMLS via Orphanet 74 C0039984
ICD10 via Orphanet 34 G54.0
MESH via Orphanet 45 D013901
UMLS 73 C0039984

Summaries for Thoracic Outlet Syndrome

NINDS : 54 TOS is an umbrella term that encompasses three related syndromes that involve compression of the nerves, arteries, and veins in the lower neck and upper chest area and cause pain in the arm, shoulder, and neck.  Most doctors agree that TOS is caused by compression of the brachial plexus or subclavian vessels as they pass through narrow passageways leading from the base of the neck to the armpit and arm, but there is considerable disagreement about its diagnosis and treatment. Making the diagnosis of TOS even more difficult is that a number of disorders feature symptoms similar to those of TOS, including rotator cuff injuries, cervical disc disorders, fibromyalgia, multiple sclerosis, complex regional pain syndrome, and tumors of the syrinx or spinal cord.  The disorder can sometimes be diagnosed in a physical exam by tenderness in the supraclavicular area, weakness and/or a "pins and needles" feeling when elevating the hands, weakness in the fifth ("little") finger, and paleness in the palm of one or both hands when the individual raises them above the shoulders, with the fingers pointing to the ceiling.  Symptoms of TOS vary depending on the type. Neurogenic TOS has a characteristic sign, called the Gilliatt-Sumner hand, in which there is severe wasting in the fleshy base of the thumb.  Other symptoms include paresthesias (pins and needles sensation or numbness) in the fingers and hand, change in hand color, hand coldness, or dull aching pain in the neck, shoulder, and armpit.  Venous TOS features pallor, a weak or absent pulse in the affected arm, which also may be cool to the touch and appear paler than the unaffected arm.  Symptoms may include numbness, tingling, aching, swelling of the extremity and fingers, and weakness of the neck or arm.  Arterial TOS most prominently features change in color and cold sensitivity in the hands and fingers, swelling, heaviness, paresthesias and poor blood circulation in the arms, hands, and fingers. There are many causes of TOS, including physical trauma, anatomical defects, tumors that press on nerves, poor posture that causes nerve compression, pregnancy, and repetitive arm and shoulder movements and activity, such as from playing certain sports.   TOS is more common in women.  The onset of symptoms usually occurs between 20 and 50 years of age.  Doctors usually recommend nerve conduction studies, electromyography, or imaging studies to confirm or rule out a diagnosis of TOS.

MalaCards based summary : Thoracic Outlet Syndrome, also known as tos, is related to neurogenic thoracic outlet syndrome and venous thoracic outlet syndrome, and has symptoms including back pain, headache and pain. An important gene associated with Thoracic Outlet Syndrome is POLA1 (DNA Polymerase Alpha 1, Catalytic Subunit). The drugs Dexmedetomidine and Ketamine have been mentioned in the context of this disorder. Affiliated tissues include testes, spinal cord and lung, and related phenotypes are abnormality of the ribs and edema

Disease Ontology : 12 A vascular disease that is characterized by compression at the superior thoracic outlet[1] resulting from excess pressure placed on a neurovascular bundle passing between the anterior scalene and middle scalene muscles.

NIH Rare Diseases : 53 Thoracic outlet syndromes (TOSs) are a group of disorders with one common feature: the compression of 1 or more of the nerves and/or blood vessels just above the first rib and behind the collarbone. There are 4 recognized subtypes of TOS, each with a distinct cause and pattern of symptoms. A fifth subtype is controversial. While thoracic outlet syndromes as a group are not rare, individual subtypes of TOS are considered rare. The subtypes include:Arterial TOS (A-TOS) - due to compression of the subclavian artery, most commonly caused by a cervical rib. Symptoms may include blood clots, arm pain with exertion, or acute arterial thrombosis (sudden blood flow obstruction in an artery). Venous TOS (V-TOS) - due to compression of the subclavian vein, often associated with repetitive arm activities. It may cause pain, swelling, and deep vein thrombosis. Traumatic neurovascular TOS - occurs after trauma to the collarbone and may affect both nerves and vessels. Symptoms may include pain, swelling, bruising, weakness, and loss of sensation in the arm and hand. True neurogenic TOS (TN-TOS) - caused by compression of the brachial plexus. Symptoms include numbness, abnormal sensations, and weakness of the arms and shoulders, as well as pain in the neck, shoulder or hand. Disputed TOS - the vast majority of neurogenic cases. It is controversial whether it is a true form of TOS because it lacks a consistent physical abnormality, a recognized cause, consistent symptoms, a reliable method of testing, and a standard treatment. Pain and tingling or numbness in the neck, arm and hand are common complaints. Treatment for TOS depends on the type and whether symptoms are present. Treatment may involve physical therapy, oral or injected medication (e.g. pain medicine or steroids), thoracic outlet decompression surgery, and/or thrombolytic therapy.

MedlinePlus : 43 Thoracic outlet syndrome (TOS) causes pain in the shoulder, arm, and neck. It happens when the nerves or blood vessels just below your neck are compressed, or squeezed. The compression can happen between the muscles of your neck and shoulder or between the first rib and collarbone. You may feel burning, tingling, and numbness along your arm, hand, and fingers. If a nerve is compressed, you may also feel weakness in your hand. If a vein is compressed, your hand might be sensitive to cold, or turn pale or bluish. Your arm might swell and tire easily. TOS is more common in women. It usually starts between 20 and 50 years of age. Doctors do nerve and imaging studies to diagnose it. There are many causes of TOS, including Injury Anatomical defects Tumors that press on nerves Poor posture that causes nerve compression Pregnancy Repetitive arm and shoulder movements and activity, such as from playing certain sports Treatment depends on what caused your TOS. Medicines, physical therapy, and relaxation might help. Surgery may also be an option. Most people recover. NIH: National Institute of Neurological Disorders and Stroke

Wikipedia : 76 Thoracic outlet syndrome (TOS) is a condition in which there is compression of the nerves, arteries, or... more...

Related Diseases for Thoracic Outlet Syndrome

Diseases related to Thoracic Outlet Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 neurogenic thoracic outlet syndrome 12.3
2 venous thoracic outlet syndrome 12.3
3 arterial thoracic outlet syndrome 12.3
4 twin-to-twin transfusion syndrome 12.0
5 hemolytic anemia, nonspherocytic, due to hexokinase deficiency 11.9
6 insensitivity to pain, congenital, with anhidrosis 11.9
7 thrombophilia due to activated protein c resistance 11.9
8 adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency 11.9
9 disordered steroidogenesis due to cytochrome p450 oxidoreductase deficiency 11.9
10 neuropathy, hereditary, with liability to pressure palsies 11.9
11 severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiency 11.9
12 thrombophilia due to thrombin defect 11.9
13 adrenal hyperplasia, congenital, due to steroid 11-beta-hydroxylase deficiency 11.9
14 dystonia, dopa-responsive, due to sepiapterin reductase deficiency 11.9
15 homocystinuria due to deficiency of n -methylenetetrahydrofolate reductase activity 11.9
16 anemia, nonspherocytic hemolytic, due to g6pd deficiency 11.8
17 adrenal hyperplasia, congenital, due to 17-alpha-hydroxylase deficiency 11.8
18 megaloblastic anemia due to dihydrofolate reductase deficiency 11.8
19 homocystinuria due to cystathionine beta-synthase deficiency 11.8
20 thrombophilia due to thrombomodulin defect 11.8
21 adenylate kinase deficiency, hemolytic anemia due to 11.8
22 severe combined immunodeficiency with sensitivity to ionizing radiation 11.8
23 gamma-glutamylcysteine synthetase deficiency, hemolytic anemia due to 11.8
24 glutathione synthetase deficiency of erythrocytes, hemolytic anemia due to 11.8
25 homocystinuria due to cbs deficiency 11.8
26 myopathy due to myoadenylate deaminase deficiency 11.8
27 pseudohyperkalemia, familial, 2, due to red cell leak 11.8
28 hemolytic anemia, nonspherocytic, due to glucose phosphate isomerase deficiency 11.8
29 methemoglobinemia due to deficiency of methemoglobin reductase 11.8
30 thrombophilia due to protein c deficiency, autosomal recessive 11.8
31 thrombocytopenia due to platelet alloimmunization 11.8
32 hereditary neuropathy with liability to pressure palsy 11.8
33 ornithine transcarbamylase deficiency, hyperammonemia due to 11.8
34 muscular dystrophy, congenital, due to integrin alpha-7 deficiency 11.8
35 severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation 11.8
36 carbamoyl phosphate synthetase i deficiency, hyperammonemia due to 11.8
37 hyperphenylalaninemia due to dehydratase deficiency 11.8
38 classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency 11.8
39 uridine 5-prime monophosphate hydrolase deficiency, hemolytic anemia due to 11.7
40 chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids 11.7
41 encephalopathy due to defective mitochondrial and peroxisomal fission 1 11.7
42 hypermethioninemia due to adenosine kinase deficiency 11.7
43 methylmalonic aciduria due to methylmalonyl-coa mutase deficiency 11.7
44 mitochondrial complex i deficiency due to acad9 deficiency 11.7
45 cataract, microcephaly, failure to thrive, kyphoscoliosis syndrome 11.7
46 indifference to pain, congenital, autosomal recessive 11.7
47 hydrocephalus due to congenital stenosis of aqueduct of sylvius 11.7
48 metachromatic leukodystrophy due to saposin b deficiency 11.7
49 familial hyperthyroidism due to mutations in tsh receptor 11.7
50 thrombophilia due to histidine-rich glycoprotein deficiency 11.7

Graphical network of the top 20 diseases related to Thoracic Outlet Syndrome:



Diseases related to Thoracic Outlet Syndrome

Symptoms & Phenotypes for Thoracic Outlet Syndrome

Human phenotypes related to Thoracic Outlet Syndrome:

59 32 (show all 11)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormality of the ribs 59 32 frequent (33%) Frequent (79-30%) HP:0000772
2 edema 59 32 frequent (33%) Frequent (79-30%) HP:0000969
3 muscle weakness 59 32 frequent (33%) Frequent (79-30%) HP:0001324
4 varicose veins 59 32 occasional (7.5%) Occasional (29-5%) HP:0002619
5 arthralgia 59 32 frequent (33%) Frequent (79-30%) HP:0002829
6 myalgia 59 32 frequent (33%) Frequent (79-30%) HP:0003326
7 muscle cramps 59 32 occasional (7.5%) Occasional (29-5%) HP:0003394
8 paresthesia 59 32 hallmark (90%) Very frequent (99-80%) HP:0003401
9 emg abnormality 59 32 occasional (7.5%) Occasional (29-5%) HP:0003457
10 venous thrombosis 59 32 occasional (7.5%) Occasional (29-5%) HP:0004936
11 sensory neuropathy 59 Occasional (29-5%)

UMLS symptoms related to Thoracic Outlet Syndrome:


back pain, headache, pain, sciatica, seizures, syncope, tremor, chronic pain, vertigo/dizziness, sleeplessness

GenomeRNAi Phenotypes related to Thoracic Outlet Syndrome according to GeneCards Suite gene sharing:

26 (show all 14)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.47 HHAT
2 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.47 HHAT
3 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.47 HHAT
4 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.47 SIRPA
5 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.47 SIRPA
6 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.47 SIRPA
7 Increased shRNA abundance (Z-score > 2) GR00366-A-195 9.47 HHAT
8 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.47 SIRPA
9 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.47 HHAT
10 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.47 HHAT
11 Increased shRNA abundance (Z-score > 2) GR00366-A-51 9.47 HHAT SIRPA
12 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.47 SIRPA
13 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.47 HHAT
14 Increased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor) GR00198-A-1 8.96 GSTO1 SIRPA

Drugs & Therapeutics for Thoracic Outlet Syndrome

Drugs for Thoracic Outlet Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 52)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
2
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
3
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
4 Neurotransmitter Agents Phase 4,Phase 2,Phase 1,Not Applicable
5 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1,Not Applicable
6 Adrenergic Agents Phase 4
7 Adrenergic Agonists Phase 4
8 Adrenergic alpha-2 Receptor Agonists Phase 4
9 Adrenergic alpha-Agonists Phase 4
10 Analgesics Phase 4
11 Analgesics, Non-Narcotic Phase 4
12 Anesthetics Phase 4,Not Applicable
13 Anesthetics, Dissociative Phase 4
14 Anesthetics, General Phase 4,Not Applicable
15 Anesthetics, Intravenous Phase 4,Not Applicable
16 Central Nervous System Depressants Phase 4,Not Applicable
17 Excitatory Amino Acid Antagonists Phase 4
18 Excitatory Amino Acids Phase 4
19 Hypnotics and Sedatives Phase 4,Not Applicable
20 Pharmaceutical Solutions Phase 4,Phase 3
21 Kallikreins Phase 3
22 Plasma Kallikrein Phase 3
23
Acetylcholine Approved Phase 2,Phase 1 51-84-3 187
24
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
25
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
26 abobotulinumtoxinA Phase 2,Phase 1
27 Botulinum Toxins Phase 2,Phase 1
28 Botulinum Toxins, Type A Phase 2,Phase 1
29 Cholinergic Agents Phase 2,Phase 1,Not Applicable
30 Neuromuscular Agents Phase 2,Phase 1
31 onabotulinumtoxinA Phase 2,Phase 1
32 incobotulinumtoxinA Phase 1
33
Triamcinolone Approved, Vet_approved 124-94-7 31307
34
Nicotine Approved Not Applicable 54-11-5 942 89594
35
Benzocaine Approved, Investigational Not Applicable 1994-09-7, 94-09-7 2337
36
Carbon monoxide Approved, Investigational Not Applicable 630-08-0 281
37 tannic acid Approved, Nutraceutical Not Applicable
38
Lutein Approved, Investigational, Nutraceutical Not Applicable 127-40-2 6433159
39 Liver Extracts
40 triamcinolone acetonide
41 Triamcinolone diacetate
42 Triamcinolone hexacetonide
43
Bisphenol A 80-05-7 6623
44 Endocrine Disruptors
45 Autonomic Agents Not Applicable
46 Central Nervous System Stimulants Not Applicable
47 Nicotinic Agonists Not Applicable
48 Antimetabolites Not Applicable
49 Antioxidants Not Applicable
50 Protective Agents Not Applicable

Interventional clinical trials:

(show all 30)
# Name Status NCT ID Phase Drugs
1 The Effects of Dexmedetomidine on Early Stage Renal Functions in Pediatric Patients Completed NCT01948336 Phase 4 Dexmedetomidine;Ketamine;Propofol
2 Safety and Efficacy Study of Repeated Doses of DX-88 (Ecallantide) to Treat Attacks of Hereditary Angioedema (HAE) Completed NCT00456508 Phase 3 ecallantide
3 Efficacy and Safety Study of DX-88 to Treat Acute Attacks of Hereditary Angioedema (HAE) Completed NCT00262080 Phase 3 ecallantide;Phosphate Buffer Saline (PBS),
4 Plate Osteosynthesis Versus ESIN of Displaced Midclavicular Fractures Completed NCT01015924 Phase 2, Phase 3
5 Efficacy Study of DX-88 (Ecallantide) to Treat Acute Attacks of Hereditary Angioedema (HAE) Completed NCT00457015 Phase 3 ecallantide;Phosphate Buffer Saline (PBS), pH 7.0
6 Treatment of Thoracic Outlet Syndrome (TOS) With Botox Completed NCT00444886 Phase 2 Botulinum Toxin Type A injection (BOTOX);Botulinum Toxin Type A injection (BOTOX)
7 Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer Active, not recruiting NCT01898494 Phase 2 cisplatin;carboplatin
8 Botulinum Toxin Injections for Thoracic Outlet Syndrome Unknown status NCT01405482 Phase 1 Botulinum Toxin Type A
9 Study of Serum Levels of Oxidative Stress Markers in Ovarian Hyperstimulation Patients Unknown status NCT02202278
10 Oxidative Stress and Bisphenol A (BPA) Impact With Polycystic Ovary Syndrome (PCOS) Unknown status NCT01600872
11 Impact of JuicePlus+ on the Health Status of an Overweight Stressed Population Unknown status NCT02512107 Not Applicable
12 The Effects of Mindsets on the Brain's Response to Food Cues Unknown status NCT01913743
13 Thoracic Outlet Syndrome: Case Reports and Analysis With Ultrasound Imaging Completed NCT01196637
14 The Effectiveness of Diagnosis and Treatment of Thoracic Outlet Syndrome Completed NCT01342068
15 Study of Urethral Mobility in Male Stress Urinary Incontinence Pre- and Post- Placement of Transobturator Sling Completed NCT01779323
16 Lung Cancer Informational Study (LCIS) Completed NCT00579215 Not Applicable
17 Consumption of Apple Juice in Hemodialysis Patients Completed NCT02974491 Not Applicable
18 Pharmacokinetic Profile of Toxic Substances and Nicotine in Electronic Cigarettes Completed NCT01665066 Not Applicable
19 Does the Use of Bispectral Index Reduce the Oxidative Stress in Endoscopic Retrograde Cholangiopancreatography? Completed NCT02792751 Not Applicable
20 The Influence of Lutein Supplements on Age-related Macular Degeneration Completed NCT01042860 Not Applicable
21 Carbon Monoxide and Oxidative Stress in Waterpipe Smokers Completed NCT02937415 Not Applicable
22 Systematic Transcutaneous Oxymetry Use in Thoracic Outlet Syndrome Recruiting NCT03355274 Not Applicable
23 Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma Recruiting NCT02984410 Not Applicable
24 Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer Recruiting NCT03210103 Not Applicable
25 Effect of Non-surgical Periodontal Treatment on Oxidative Stress and Antioxidant Status in OSAS Recruiting NCT03268473 Not Applicable
26 Efficacy of Wet Cupping on Reactive Oxygen Species and Antioxidants Active, not recruiting NCT03503903 Not Applicable
27 Oxidative Stress in Women Treated With Atosiban for Impending Preterm Birth Active, not recruiting NCT03570294 Not Applicable Atosiban
28 A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss Not yet recruiting NCT03515889 Not Applicable
29 Sleep Disturbances and Biomarkers of Sarcopenic OBesity Not yet recruiting NCT03175601
30 Weight Loss Using a Feedback Device in Obese People With the Metabolic Syndrome Withdrawn NCT03491930 Not Applicable

Search NIH Clinical Center for Thoracic Outlet Syndrome

Cochrane evidence based reviews: thoracic outlet syndrome

Genetic Tests for Thoracic Outlet Syndrome

Genetic tests related to Thoracic Outlet Syndrome:

# Genetic test Affiliating Genes
1 Abnormality of Toe 29

Anatomical Context for Thoracic Outlet Syndrome

MalaCards organs/tissues related to Thoracic Outlet Syndrome:

41
Testes, Spinal Cord, Lung, Ovary, Liver, Brain, Bone

Publications for Thoracic Outlet Syndrome

Articles related to Thoracic Outlet Syndrome:

(show top 50) (show all 679)
# Title Authors Year
1
Long-Term Functional Outcome of Surgical Treatment for Thoracic Outlet Syndrome. ( 29329197 )
2018
2
Outcomes following operative management of thoracic outlet syndrome in the pediatric patients. ( 29301465 )
2018
3
Secondary Chondrosarcoma Presenting with Symptoms Similar to Thoracic Outlet Syndrome. ( 29721343 )
2018
4
Neurogenic Thoracic Outlet Syndrome Caused by Vascular Compression of the Brachial Plexus: A Report of Two Cases. ( 29497457 )
2018
5
A Prospective Evaluation of Duplex Ultrasound for Thoracic Outlet Syndrome in High-Performance Musicians Playing Bowed String Instruments ( 29370085 )
2018
6
Amnion membrane improves results in treating neurogenic thoracic outlet syndrome. ( 29942911 )
2018
7
WITHDRAWN: After a motor vehicle accident is it neurogenic thoracic outlet syndrome or ulnar entrapment syndrome? How to make the correct diagnosis. ( 29627065 )
2018
8
WITHDRAWN: Commentary to accompany "After motor vehicle accidents is it thoracic outlet syndrome or ulnar entrapment syndrome? How to make the correct diagnosis". ( 29573776 )
2018
9
Thoracic outlet syndrome presenting with subclavian vein thrombosis. ( 29369936 )
2018
10
Safety and Efficacy of Catheter-Directed Therapies as a Supplement to Surgical Decompression in Venous Thoracic Outlet Syndrome. ( 29112470 )
2018
11
First Rib Resection for Thoracic Outlet Syndrome: The Robotic Approach. ( 29696329 )
2018
12
Influence of Body Weight on Surgical Treatment for Neurogenic Thoracic Outlet Syndrome. ( 29421422 )
2018
13
Long-term outcomes after surgical treatment of pediatric neurogenic thoracic outlet syndrome. ( 29125442 )
2018
14
T1 Paravertebral Catheter for Postoperative Pain Management After First Rib Resection for Venous Thoracic Outlet Syndrome: A Case Report. ( 29634572 )
2018
15
The Gilliatt-Sumner hand - a diagnostic clue of neurogenic thoracic outlet syndrome. ( 29931301 )
2018
16
Concomitant neurogenic and vascular thoracic outlet syndrome due to multiple exostoses. ( 29336398 )
2018
17
Percutaneous leadless pacemaker implantation in a patient with bilateral venous thoracic outlet syndrome. ( 29792384 )
2018
18
Morbidity of First Rib Resection in the Surgical Repair of Thoracic Outlet Syndrome. ( 29504475 )
2018
19
Thoracic Outlet Syndrome: Biomechanical and Exercise Considerations. ( 29921751 )
2018
20
A Patient-Centered Approach to Guide Follow-Up and Adjunctive Testing and Treatment after First Rib Resection for Venous Thoracic Outlet Syndrome Is Safe and Effective. ( 29360741 )
2018
21
The Art of Caring in the Treatment of Thoracic Outlet Syndrome. ( 29783723 )
2018
22
Cervical Rib Prevalence and its Association with Thoracic Outlet Syndrome: A Meta-Analysis of 141 Studies with Surgical Considerations. ( 29203316 )
2018
23
Novel Surgical Approach for Decompression of the Scalene Triangle in Neurogenic Thoracic Outlet Syndrome. ( 29396981 )
2018
24
Transaxillary decompression of thoracic outlet syndrome patients presenting with cervical ribs. ( 29705086 )
2018
25
Surgical Missteps in the Management of Venous Thoracic Outlet Syndrome Which Lead to Reoperation. ( 29477681 )
2018
26
Thoracoscopic Versus Transaxillary Approach to First Rib Resection in Thoracic Outlet Syndrome. ( 29289365 )
2018
27
Diagnosing Thoracic Outlet Syndrome: Current Approaches and Future Directions. ( 29558408 )
2018
28
Commentary: Comments on thoracic outlet syndrome. ( 29336399 )
2018
29
Thoracic Outlet Syndrome: A Unique Presentation of a Primary Intrathoracic Goiter. ( 29975576 )
2018
30
Outcomes of Transaxillary Approach to Cervical and First-Rib Resection for Neurogenic Thoracic Outlet Syndrome. ( 29772332 )
2018
31
Harvey Cushing's management of neurogenic thoracic outlet syndrome. ( 29652235 )
2018
32
Thoracic outlet syndrome for thoracic surgeons. ( 29628349 )
2018
33
Arterial Thoracic Outlet Syndrome Treated Successfully with Totally Endoscopic First Rib Resection. ( 28845317 )
2017
34
Is thoracic outlet syndrome common after Nuss procedure? ( 29307618 )
2017
35
Left subclavian artery malperfusion due to thoracic outlet syndrome during total vertebrectomy for invasive lung cancer: a case report. ( 29457104 )
2017
36
Associations between clinical diagnostic criteria and pretreatment patient-reported outcomes measures in a prospective observational cohort of patients with neurogenic thoracic outlet syndrome. ( 28735950 )
2017
37
New Diagnostic and Treatment Modalities for Neurogenic Thoracic Outlet Syndrome. ( 28555024 )
2017
38
Frequency of the pectoralis minor compression syndrome in patients treated for thoracic outlet syndrome. ( 28943489 )
2017
39
MRI of thoracic outlet syndrome in children. ( 28493011 )
2017
40
Perioperative Outcomes of Thoracic Outlet Syndrome Surgical Repair in a Nationally Validated Database. ( 28537129 )
2017
41
Video-assisted thoracoscopic surgery for intrathoracic first rib resection in thoracic outlet syndrome. ( 28840002 )
2017
42
Paget-Schroetter Syndrome Resulting from Thoracic Outlet Syndrome and KAATSU Training. ( 28883228 )
2017
43
Critical Upper Limb Ischemia Due to Brachial Tourniquet in Misdiagnosed Thoracic Outlet Syndrome after Carpal Tunnel Decompression: A Case Report. ( 29218290 )
2017
44
Clinical presentation and management of arterial thoracic outlet syndrome. ( 28189360 )
2017
45
Ultrasonographic Diagnosis of Thoracic Outlet Syndrome Secondary to Brachial Plexus Piercing Variation. ( 28677632 )
2017
46
Creating a Registry for Patients with Thoracic Outlet Syndrome. ( 28629121 )
2017
47
Successful repair of thoracic outlet syndrome in a growing young patient due to posterior sternoclavicular joint dislocation. ( 29268434 )
2017
48
Thoracic outlet syndrome as a consequence of isolated atraumatic first rib fracture. ( 28616159 )
2017
49
Dynamic CT angiography for the diagnosis of patients with thoracic outlet syndrome: Correlation with patient symptoms. ( 29233633 )
2017
50
An unusual case of neurogenic thoracic outlet syndrome. ( 28135679 )
2017

Variations for Thoracic Outlet Syndrome

Expression for Thoracic Outlet Syndrome

Search GEO for disease gene expression data for Thoracic Outlet Syndrome.

Pathways for Thoracic Outlet Syndrome

GO Terms for Thoracic Outlet Syndrome

Molecular functions related to Thoracic Outlet Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 SH3 domain binding GO:0017124 8.62 FMN1 SIRPA

Sources for Thoracic Outlet Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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