MCID: THR016
MIFTS: 54

Thrombophlebitis

Categories: Blood diseases, Cardiovascular diseases

Aliases & Classifications for Thrombophlebitis

MalaCards integrated aliases for Thrombophlebitis:

Name: Thrombophlebitis 12 30 56 45 15 74
Phlebitis and Thrombophlebitis of Superficial Vessels of Lower Extremities 12
Thrombophlebitis of Superficial Veins of Lower Extremity 12
Thrombophlebitis of a Superficial Leg Vein 12
Superficial Thrombophlebitis of Leg 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3875
ICD9CM 36 451.0
MeSH 45 D013924
NCIt 51 C3410
SNOMED-CT 69 40283005 64156001
ICD10 34 I80.0

Summaries for Thrombophlebitis

Disease Ontology : 12 A phlebitis that results from a blood clot in the vessel.

MalaCards based summary : Thrombophlebitis, also known as phlebitis and thrombophlebitis of superficial vessels of lower extremities, is related to lemierre's syndrome and varicose veins. An important gene associated with Thrombophlebitis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Ciprofloxacin and Cefuroxime have been mentioned in the context of this disorder. Affiliated tissues include myeloid, brain and skin, and related phenotypes are homeostasis/metabolism and integument

Wikipedia : 77 Thrombophlebitis is a phlebitis (inflammation of a vein) related to a thrombus (blood... more...

Related Diseases for Thrombophlebitis

Diseases related to Thrombophlebitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 300)
# Related Disease Score Top Affiliating Genes
1 lemierre's syndrome 33.5 MTHFR SERPINE1
2 varicose veins 32.1 F2 F5 MTHFR SERPINC1
3 mesenteric vascular occlusion 30.0 F2 MTHFR
4 protein c deficiency 30.0 F2 F5 MTHFR SERPINC1
5 chronic venous insufficiency 30.0 PLAT SERPINE1
6 pleuropneumonia 30.0 PLAT SERPINC1
7 venous insufficiency 29.9 F2 PLAT SERPINE1
8 homocystinuria 29.7 F5 MTHFR SERPINC1
9 behcet syndrome 29.7 APOH F5 SERPINC1
10 coronary thrombosis 29.7 PLAT SERPINC1 SERPINE1
11 endocarditis 29.7 APOH F2 PLAT SERPINC1
12 arteries, anomalies of 29.7 PLAT SERPINC1 SERPINE1
13 purpura 29.6 APOH F2 SERPINC1
14 factor v deficiency 29.6 F2 F5 F8
15 buerger disease 29.5 APOH F2 MTHFR SERPINE1
16 peripheral vascular disease 29.4 F2 PLAT SERPINC1 SERPINE1
17 factor xii deficiency 29.3 APOH F5 SERPINC1
18 post-thrombotic syndrome 29.3 F2 F5 F8 SERPINC1 SERPINE1
19 coronary artery anomaly 29.3 F2 F5 PLAT SERPINE1
20 hepatic infarction 29.2 APOH F2 MTHFR SERPINC1
21 antithrombin iii deficiency 29.0 APOH F2 F5 MTHFR SERPINC1
22 pulmonary embolism 29.0 APOH F2 F5 MTHFR PLAT SERPINC1
23 heart disease 28.9 F2 F8 MTHFR PLAT SERPINC1 SERPINE1
24 thrombosis 28.9 APOH F2 F5 F8 MTHFR PLAT
25 antiphospholipid syndrome 28.9 APOH F2 F5 MTHFR PLAT SERPINC1
26 protein s deficiency 28.8 APOH F2 F5 MTHFR SERPINC1
27 budd-chiari syndrome 28.8 APOH F2 F5 MTHFR SERPINC1
28 disseminated intravascular coagulation 28.7 F2 F5 PLAT SERPINC1 SERPINE1 SERPINF2
29 vein disease 28.6 F2 F5 F8 MTHFR PLAT SERPINC1
30 thrombophilia due to thrombin defect 28.6 APOH F2 F5 F8 MTHFR PLAT
31 intracranial hypertension 28.4 APOH F2 F5 MTHFR SERPINC1 SERPINE1
32 vascular disease 28.3 APOH F2 F5 MTHFR PLAT SERPINC1
33 myocardial infarction 28.1 F2 F5 F8 MTHFR PLAT SERPINC1
34 thrombophilia 28.0 APOH F2 F5 F8 MTHFR SERPINC1
35 thrombophilia due to activated protein c resistance 27.2 APOH F2 F5 F8 MTHFR PLAT
36 thrombophlebitis migrans 12.6
37 femoral vein thrombophlebitis 12.5
38 iliac vein thrombophlebitis 12.3
39 mondor disease 12.1
40 leech infestation 10.3 F2 SERPINC1
41 ischemic neuropathy 10.3 F2 MTHFR
42 esophageal varix 10.3 F2 SERPINC1
43 anterior spinal artery syndrome 10.3 F2 SERPINC1
44 paracetamol poisoning 10.3 F2 F5
45 posterior myocardial infarction 10.3 PLAT SERPINC1
46 encephalopathy, familial, with neuroserpin inclusion bodies 10.3 PLAT SERPINC1
47 hypersplenism 10.3 F2 SERPINC1
48 appendicitis 10.3
49 hemoglobin e disease 10.3 F2 F5
50 aspirin allergy 10.3 SERPINC1 SERPINE1

Graphical network of the top 20 diseases related to Thrombophlebitis:



Diseases related to Thrombophlebitis

Symptoms & Phenotypes for Thrombophlebitis

MGI Mouse Phenotypes related to Thrombophlebitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.02 APOH F2 F5 F8 MTHFR PLAT
2 integument MP:0010771 9.73 F2 F5 MTHFR PLAT SERPINE1 TGFB1
3 mortality/aging MP:0010768 9.61 APOH F2 F5 F8 MTHFR PLAT
4 liver/biliary system MP:0005370 9.55 F5 MTHFR SERPINC1 SERPINE1 TGFB1
5 reproductive system MP:0005389 9.1 F2 F8 MTHFR PLAT SERPINC1 TGFB1

Drugs & Therapeutics for Thrombophlebitis

Drugs for Thrombophlebitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 187)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
2
Cefuroxime Approved Phase 4 55268-75-2 5479529 5361202
3
Metronidazole Approved Phase 4,Phase 1 443-48-1 4173
4
Dalteparin Approved Phase 4,Phase 3,Phase 1 9005-49-6
5
Heparin Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 9005-49-6 46507594 772
6
Ibuprofen Approved Phase 4 15687-27-1 3672
7
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
8
Etomidate Approved Phase 4 33125-97-2 667484 36339
9
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
10
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
11
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
12
Conivaptan Approved, Investigational Phase 4 210101-16-9 151171
13
Polidocanol Approved Phase 4,Not Applicable 9002-92-0
14
Calcium Approved, Nutraceutical Phase 4,Phase 3,Phase 1 7440-70-2 271
15 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 1
16 Antiparasitic Agents Phase 4,Phase 3,Phase 1
17 Anesthetics Phase 4
18 cefuroxime axetil Phase 4
19 Anti-Infective Agents Phase 4,Phase 3,Phase 1
20 Antitubercular Agents Phase 4,Phase 3
21 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1
22 Antiprotozoal Agents Phase 4,Phase 3,Phase 1
23 Fibrinolytic Agents Phase 4,Phase 3,Phase 1
24 Antirheumatic Agents Phase 4
25 Analgesics, Non-Narcotic Phase 4
26 Analgesics Phase 4
27 calcium heparin Phase 4,Phase 3,Phase 1,Not Applicable
28 Anti-Inflammatory Agents Phase 4,Phase 3
29 Cyclooxygenase Inhibitors Phase 4
30 Heparin, Low-Molecular-Weight Phase 4,Phase 3,Phase 1
31 Anti-Inflammatory Agents, Non-Steroidal Phase 4
32 Peripheral Nervous System Agents Phase 4,Phase 3
33 Anticoagulants Phase 4,Phase 3,Phase 1
34 Heparinoids Phase 4,Phase 3
35 Salicylates Phase 4
36 Calcium, Dietary Phase 4,Phase 3,Phase 1
37 Anesthetics, Intravenous Phase 4
38 Analgesics, Opioid Phase 4
39 GABA Modulators Phase 4
40 Anti-Anxiety Agents Phase 4,Phase 3
41 Narcotics Phase 4
42 Adjuvants, Anesthesia Phase 4
43 Neurotransmitter Agents Phase 4,Phase 3
44 Tranquilizing Agents Phase 4,Phase 3
45 Psychotropic Drugs Phase 4,Phase 3
46 Hypnotics and Sedatives Phase 4
47 Central Nervous System Depressants Phase 4,Phase 3
48 Anesthetics, General Phase 4
49 GABA Agents Phase 4
50 Natriuretic Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 55)
# Name Status NCT ID Phase Drugs
1 Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis Unknown status NCT02505581 Phase 4 Extra dosage - cefuroxime (750mg) I.V;Cefuroxime 750mg oral;Metronidazole 250mg oral;Metronidazole 1,5gr Intravenous;Cefuroxime 1g Intravenous
2 Management of Superficial Thrombophlebitis Completed NCT00264381 Phase 4 Dalteparin sodium injection
3 Topical Diclofenac Gel in Patients With Superficial Inflammation of the Veins Completed NCT00377806 Phase 4 Diclofenac gel
4 Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose Veins Completed NCT02346058 Phase 4 Esarin Gel
5 Efficacy of Low Molecular Weight Heparin in Superficial Vein Thrombosis Completed NCT01245998 Phase 4 Dalteparin;Dalteparin
6 Etomidate vs Propofol-Induction Characteristics Completed NCT02807610 Phase 4 Inj Etomidate;Injection Propofol;Placebo for Propofol
7 A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia Completed NCT00435591 Phase 4 Conivaptan;placebo
8 Prophylaxis of Ileostomy Closure Site Hernia by Placing Mesh Recruiting NCT02226887 Phase 4
9 Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs Withdrawn NCT02988063 Phase 4 Polidocanol Endovenous Microfoam (PEM)
10 Safety and Efficacy of Oral Versus Intravenous Amiodarone in the Treatment of AF Unknown status NCT01817439 Phase 3 Amiodarone
11 Phlogenzym® in Patients With Acute Thrombophlebitis - Efficacy and Tolerance Completed NCT03470337 Phase 3 Phlogenzym
12 Efficacy and Tolerability of Hirudoid Cream in Prophylaxis and Treatment Infusion Phlebitis Completed NCT01943006 Phase 3 Hirudoid cream 0.3 % Mucopolysaccharide polysulfate;Placebo cream without active substance
13 Evaluation Of Fondaparinux (Also Called ARIXTRA) 2.5 mg Subcutaneously Once Daily For The Treatment Of Superficial Thrombophlebitis (Also Known As Superficial Vein Thrombosis) Completed NCT00443053 Phase 3 Fondaparinux 2.5mg or placebo
14 Different Doses and Duration of Low Molecular Weight Heparin (Parnaparin)in Superficial Vein Thrombosis Completed NCT00362947 Phase 3 LMWH parnaparin subcutaneously
15 Evaluation of Long-Term Sequelae After Thrombophlebitis, i.e. Deep Venous Thrombosis of the Lower Extremities Completed NCT00628576 Phase 3 unfractionated heparin;Tinzaparin (Leo)
16 Efficacy and Safety of Fosaprepitant Dimeglumine in Preventing Chemotherapy-Induced Nausea and Vomiting (MK-0517-031) Completed NCT01594749 Phase 3 Fosaprepitant dimeglumine;Fosaprepitant Placebo;Dexamethasone;Ondansetron;Dexamethasone Placebo;Ondansetron Placebo;Rescue Therapy
17 Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF) Completed NCT00000517 Phase 3 warfarin
18 Efficacy Comparison of Topical and Intravenous Tranexamic Acid to Reduce the Number of Blood Transfusions in TKA Completed NCT01881568 Phase 3 Tranexamic Acid;Tranexamic Acid
19 Prevention of Venous and Arterial Thromboembolism, in Cancer Patients Undergoing Chemotherapy, With a Low Molecular Weight Heparin (Nadroparin Calcium) Completed NCT00951574 Phase 3 Nadroparin calcium;saline solution (placebo)
20 Homeopathy for Post-operative (C. Section) Recovery Completed NCT00725569 Phase 2, Phase 3 Bellis perennis and Staphysagria (C6);Bellis perennis and Staphysagria (C30);Placebo
21 Efficacy and Safety of SmofKabiven Peripheral Versus Compounded Emulsion Completed NCT03792087 Phase 3 SmofKabiven Peripheral;Hospital compounded emulsion
22 Staphylococcus Aureus Bacteremia Antibiotic Treatment Options Recruiting NCT01792804 Phase 3 Trimethoprim-Sulfamethoxazole;Clindamycin;Linezolid;Flucloxacillin;Cloxacillin;Vancomycin;Daptomycin;Cefazolin
23 Biomarker Study of Neoadjuvant Vitamin E in Patients With Locally Treatable Prostate Cancer Terminated NCT00809458 Phase 3 Vitamin E
24 Progesterone for the Treatment of Traumatic Brain Injury III Terminated NCT00822900 Phase 3 Progesterone;Placebo
25 Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections Terminated NCT00108433 Phase 3 Cefazolin IV;Linezolid IV;Vancomycin (IV)
26 Hemin to Prevent Post-ERCP (Endoscopic Retrograde Cholangiopancreatography) Acute Pancreatitis Recruiting NCT01855841 Phase 2 Hemin;placebo
27 Treatment for Blood Clots in the Veins of the Legs Completed NCT00001713 Phase 1 Recombinant Tissue Plasminogen Activator;Heparin;Warfarin
28 Comparing Anti-XA Levels in Post-Cesarean Patients Undergoing Enoxaparin Thromboprophylaxis Completed NCT02070237 Phase 1 Enoxaparin
29 Phase I Trial of IV Fenretinide (4-HPR) Plus IV Safingol for Patients With Relapsed Malignancies Recruiting NCT01553071 Phase 1 Fenretinide (4-HPR) plus Intravenous Safingol
30 Prophylactic Antibiotics After Cesarean Recruiting NCT03187106 Phase 1 Cephalexin;Placebo;Metronidazole
31 Aromatase Inhibitors for Treatment of Uterine Leiomyomas Withdrawn NCT00945360 Phase 1 Letrozole (aromatase inhibitor)
32 Pelvic Embolisation to Reduce Recurrent Varicose Veins - Primary Unknown status NCT01901731 Not Applicable
33 Pelvic Embolisation to Reduce Recurrent Varicose Veins - Recurrent Unknown status NCT01909024 Not Applicable
34 POST (Prospective Observational Superfial Thrombophlebitis) Completed NCT00818688
35 Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression Stockings Completed NCT01793194 Not Applicable
36 Trans Radial Versus Transfemoral Route for Coronary Angiography Completed NCT02983721 Not Applicable
37 Intracranial Hypertension and Optic Nerve Sheath Diameter Completed NCT01796015 Not Applicable
38 Catheter-directed Foam Sclerotherapy With Tumescence Completed NCT02753270 Not Applicable
39 Radiofrequency Ablation vs Conventional Surgery for Superficial Venous Insufficiency Completed NCT02588911 Not Applicable
40 Evaluation of Endovenous Sclerotherapy for Treatment of Varicose Veins Completed NCT00954980
41 Compression Therapy Following Truncal Vein Endothermal Ablation And Distal Sclerotherapy Completed NCT02890563 Not Applicable
42 The Comparative Safety and Effectiveness of Warfarin and Dabigatran Prescribed in the Non-valvular Atrial Fibrillation Population With Humana Healthcare Coverage Completed NCT02061748 Observational
43 A Complex Contraception Registry Completed NCT02219269
44 Hospitalization at Home: The Acute Care Home Hospital Program for Adults Completed NCT02864420 Not Applicable
45 Hospital-Level Care at Home for Acutely Ill Adults Completed NCT03203759 Not Applicable
46 Midlines and Thrombophlebitis Recruiting NCT03725293 Not Applicable
47 Safety and Efficacy of Midline and PICC Recruiting NCT03502980 Not Applicable
48 Evaluation of Medical Device Recruiting NCT03329768
49 Study of Peripherally Inserted Venous Catheters in Cystic Fibrosis Patients Recruiting NCT03674216
50 Firazyr® Patient Registry (Icatibant Outcome Survey - IOS) Recruiting NCT01034969

Search NIH Clinical Center for Thrombophlebitis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: thrombophlebitis

Genetic Tests for Thrombophlebitis

Genetic tests related to Thrombophlebitis:

# Genetic test Affiliating Genes
1 Thrombophlebitis 30

Anatomical Context for Thrombophlebitis

MalaCards organs/tissues related to Thrombophlebitis:

42
Myeloid, Brain, Skin, Testes, Retina, Pancreas, Spinal Cord

Publications for Thrombophlebitis

Articles related to Thrombophlebitis:

(show top 50) (show all 1399)
# Title Authors Year
1
Pylephlebitis: A Case of Inferior Mesenteric Vein Thrombophlebitis in a Patient with Acute Sigmoid Diverticulitis-A Case Report and Clinical Management Review. ( 30805229 )
2019
2
Septic superficial thrombophlebitis in Klippel-Trenaunay syndrome. ( 30388396 )
2019
3
Recurrent superficial venous thrombophlebitis because of mutations in the protein C and fibrinogen genes in a young Argentinian female. ( 30632992 )
2019
4
Fusobacterium necrophorum septic pelvic thrombophlebitis after intrauterine device insertion. ( 30648745 )
2019
5
Caval replacement with parietal peritoneum tube graft for septic thrombophlebitis after hepatectomy: A case report. ( 30705726 )
2019
6
Rare case of fish bone migration: thrombophlebitis of the internal jugular vein. ( 30974504 )
2019
7
Comparison of Heparin Quick Penetrating Solution and Diclofenac Quick Penetrating Solution for the Prevention of Superficial Thrombophlebitis Caused by Peripheral Venous Cannulation: A Randomized Double-Blind Study. ( 31031497 )
2019
8
Interobserver reliability of histopathological features for distinguishing between cutaneous polyarteritis nodosa and superficial thrombophlebitis. ( 29675878 )
2018
9
Correction to: A challenging case of carbapenemase-producing Klebsiella pneumoniae septic thrombophlebitis and right mural endocarditis successfully treated with ceftazidime/avibactam. ( 29992522 )
2018
10
A challenging case of carbapenemase-producing Klebsiella pneumoniae septic thrombophlebitis and right mural endocarditis successfully treated with ceftazidime/avibactam. ( 29926399 )
2018
11
Acute Anorectal Thrombophlebitis Caused by a Protein C Deficiency. ( 29033437 )
2018
12
Managing pulmonary embolism secondary to suppurative deep vein thrombophlebitis due to community-acquired Staphylococcus aureus in a resource-poor setting. ( 29943741 )
2018
13
Multiple pyomyositis secondary to septic thrombophlebitis. ( 30340839 )
2018
14
Necrotizing Lip Infection Causing Septic Thrombophlebitis of the Neck: A Rare Variant of Lemierre Syndrome. ( 28651067 )
2018
15
Follow-up Blood Cultures: A 2.0 Diagnostic Tool in Patients With Gram-Negative Bacteremia and Septic Thrombophlebitis. ( 29099911 )
2018
16
Treatment with dalbavancin in a patient with septic thrombophlebitis of the internal jugular vein due to Staphylococcus aureus after insertion of an implantable cardioverter defibrillator. ( 29132942 )
2018
17
Trichosporon asahii septic thrombophlebitis following lower extremity amputation in an immunocompetent host. ( 29306852 )
2018
18
Pythium Keratitis Leading to Fatal Cavernous Sinus Thrombophlebitis. ( 29319595 )
2018
19
Images in Vascular Medicine. Linear morphea masquerading as superficial thrombophlebitis. ( 29334870 )
2018
20
Treatment for superficial thrombophlebitis of the leg. ( 29478266 )
2018
21
Postpartum septic pelvic thrombophlebitis after caesarean delivery: a case report. ( 29594006 )
2018
22
Immediate Superficial Venous Thrombophlebitis Associated with Intravenous Administration of Ciprofloxacin. ( 29706490 )
2018
23
Experimental Study of Phlebitis Ointment Administration in Acute Superficial Thrombophlebitis. ( 29849699 )
2018
24
Traumatic Penile Pain: A Case of Dorsal Vein Thrombophlebitis after Intercourse. ( 29850287 )
2018
25
Endovascular Thrombectomy of Septic Thrombophlebitis of the Inferior Vena Cava: Case Report and Review of the Literature. ( 29898647 )
2018
26
Septic Pulmonary Emboli From Peripheral Suppurative Thrombophlebitis: A Case Report and Literature Review. ( 29909751 )
2018
27
Specific dynamic of serum procalcitonin in critically ill patients affected by Gram-negative bacilli septic thrombophlebitis. ( 30037337 )
2018
28
Thrombophlebitis of superior mesenteric vein with bacteremia of Gemella sanguinis and Streptococcus gordonii. ( 30042036 )
2018
29
Facial vein thrombophlebitis: A case report and literature review. ( 30174005 )
2018
30
Ovarian necrosis due to S. pyogenes septic thrombophlebitis: A case report. ( 30225202 )
2018
31
Trueperella bernardiae: an unusual cause of septic thrombophlebitis in an injection drug user. ( 30310680 )
2018
32
Treatment of Lower Extremity Superficial Thrombophlebitis. ( 30383173 )
2018
33
Thrombophlebitis of the Right Renal Capsular Vein during the Early Postpartum Period. ( 30402311 )
2018
34
Prevention of Thrombophlebitis in Peripheral Intravenous Catheters: The Butterfly Effect. ( 30433918 )
2018
35
Novel short peripheral catheter design for prevention of thrombophlebitis. ( 30506866 )
2018
36
Suppurative Thrombophlebitis of the Inferior Vena Cava Resolved with Intravenous Antibiotic Therapy: A Case Report. ( 30745926 )
2018
37
Dangerous Liaisons: Pelvic Variant of Lemierre Syndrome by Right Common Iliac Vein Thrombophlebitis After Sexual Intercourse. ( 28430681 )
2017
38
Septic thrombophlebitis of the internal jugular vein, a case of Lemierre's syndrome. ( 28580216 )
2017
39
Necrotizing Thrombophlebitis Secondary to Mycobacterium Chelonae in a Hemodialyzed Patient. ( 27415637 )
2017
40
Incomplete Behçet's disease with calf muscle pain and MRI hyperintensity due to possible thrombophlebitis. ( 27748264 )
2017
41
Quantitative T2 mapping for detection and quantification of thrombophlebitis in a rabbit model. ( 27866674 )
2017
42
Mondor's disease: sclerosing thrombophlebitis of subcutaneous veins in a patient with occult carcinoma of the breast. ( 28572522 )
2017
43
Septic Thrombophlebitis with Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia and de Novo Resistance to Vancomycin and Daptomycin. ( 28626538 )
2017
44
Risk Factors for Postpartum Septic Pelvic Thrombophlebitis: A Multicenter Cohort. ( 28704844 )
2017
45
Lesson of the month 1: Spontaneous septic thrombophlebitis presenting with bacteraemia diagnosed by PET-CT scan. ( 28974602 )
2017
46
Pseudocellulitis Need Not be Benign: Three Cases of Superficial Migratory Thrombophlebitis with "Negative" Venous Duplex Ultrasonography. ( 29399267 )
2017
47
Superficial Thrombophlebitis of the Breast in a Patient with an Arteriovenous Fistula for Hemodialysis. ( 26991444 )
2016
48
Hepatic Infarction Caused by Portal Vein Thrombophlebitis Misdiagnosed as Infiltrative Hepatic Malignancy with Neoplastic Thrombus. ( 27646586 )
2016
49
Deep thrombophlebitis masked by peripheral arthritis in Henoch-Schönlein purpura. ( 25496261 )
2016
50
What Is the Most Effective Treatment of Superficial Thrombophlebitis? ( 26707361 )
2016

Variations for Thrombophlebitis

Expression for Thrombophlebitis

Search GEO for disease gene expression data for Thrombophlebitis.

Pathways for Thrombophlebitis

Pathways related to Thrombophlebitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.89 APOH F2 F5 F8 PLAT SERPINC1
2
Show member pathways
12.43 F2 F5 F8 SERPINC1
3
Show member pathways
11.96 F2 MTHFR PLAT SERPINE1
4
Show member pathways
11.7 F2 F5 F8 PLAT SERPINC1 SERPINE1
5 11.57 PLAT SERPINE1 TGFB1
6 11.31 F2 F5 F8 PLAT SERPINC1 SERPINE1
7 10.85 SERPINC1 TGFB1
8 10.55 PLAT SERPINE1 SERPINF2

GO Terms for Thrombophlebitis

Cellular components related to Thrombophlebitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.91 APOH F2 F5 F8 PLAT SERPINC1
2 extracellular exosome GO:0070062 9.88 APOH F2 PLAT SERPINC1 SERPINE1 SERPINF2
3 extracellular space GO:0005615 9.81 APOH F2 F5 F8 PLAT SERPINC1
4 cell surface GO:0009986 9.73 APOH PLAT SERPINF2 TGFB1
5 endoplasmic reticulum lumen GO:0005788 9.67 F2 F5 F8 SERPINC1
6 blood microparticle GO:0072562 9.62 F2 SERPINC1 SERPINF2 TGFB1
7 COPII-coated ER to Golgi transport vesicle GO:0030134 9.46 F5 F8
8 collagen-containing extracellular matrix GO:0062023 9.43 APOH PLAT SERPINC1 SERPINE1 SERPINF2 TGFB1
9 platelet alpha granule lumen GO:0031093 9.02 F5 F8 SERPINE1 SERPINF2 TGFB1

Biological processes related to Thrombophlebitis according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.77 F2 F5 SERPINC1
2 ER to Golgi vesicle-mediated transport GO:0006888 9.76 F2 F5 F8
3 response to hypoxia GO:0001666 9.73 MTHFR PLAT TGFB1
4 negative regulation of endopeptidase activity GO:0010951 9.72 SERPINC1 SERPINE1 SERPINF2
5 blood coagulation GO:0007596 9.72 F2 F5 F8 PLAT SERPINC1
6 negative regulation of peptidase activity GO:0010466 9.7 SERPINC1 SERPINE1 SERPINF2
7 acute-phase response GO:0006953 9.65 F2 F8 SERPINF2
8 positive regulation of collagen biosynthetic process GO:0032967 9.63 F2 SERPINF2 TGFB1
9 blood coagulation, intrinsic pathway GO:0007597 9.61 APOH F2 F8
10 blood circulation GO:0008015 9.6 F5 MTHFR
11 negative regulation of proteolysis GO:0045861 9.58 F2 PLAT
12 positive regulation of blood coagulation GO:0030194 9.58 APOH F2 SERPINE1
13 positive regulation of protein localization to nucleus GO:1900182 9.57 F2 TGFB1
14 hemostasis GO:0007599 9.56 F2 F5 F8 SERPINC1
15 negative regulation of blood coagulation GO:0030195 9.54 APOH SERPINE1
16 regulation of blood coagulation GO:0030193 9.54 APOH F2 SERPINC1
17 plasminogen activation GO:0031639 9.51 APOH PLAT
18 negative regulation of plasminogen activation GO:0010757 9.49 SERPINE1 SERPINF2
19 fibrinolysis GO:0042730 9.46 F2 PLAT SERPINE1 SERPINF2
20 negative regulation of fibrinolysis GO:0051918 9.26 APOH F2 SERPINE1 SERPINF2
21 platelet degranulation GO:0002576 9.1 APOH F5 F8 SERPINE1 SERPINF2 TGFB1

Molecular functions related to Thrombophlebitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 9.43 APOH F2 SERPINC1
2 peptidase inhibitor activity GO:0030414 9.33 SERPINC1 SERPINE1 SERPINF2
3 protease binding GO:0002020 9.13 SERPINC1 SERPINE1 SERPINF2
4 serine-type endopeptidase inhibitor activity GO:0004867 8.8 SERPINC1 SERPINE1 SERPINF2

Sources for Thrombophlebitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
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