MCID: THR016
MIFTS: 51

Thrombophlebitis

Categories: Blood diseases, Cardiovascular diseases

Aliases & Classifications for Thrombophlebitis

MalaCards integrated aliases for Thrombophlebitis:

Name: Thrombophlebitis 12 29 54 43 15 71
Phlebitis and Thrombophlebitis of Superficial Vessels of Lower Extremities 12 32
Thrombophlebitis of Superficial Veins of Lower Extremity 12
Thrombophlebitis of a Superficial Leg Vein 12
Superficial Thrombophlebitis of Leg 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3875
ICD9CM 34 451.0
MeSH 43 D013924
NCIt 49 C3410
SNOMED-CT 67 40283005 64156001
ICD10 32 I80.0
UMLS 71 C0040046 C0265057

Summaries for Thrombophlebitis

Disease Ontology : 12 A phlebitis that results from a blood clot in the vessel.

MalaCards based summary : Thrombophlebitis, also known as phlebitis and thrombophlebitis of superficial vessels of lower extremities, is related to femoral vein thrombophlebitis and lemierre's syndrome. An important gene associated with Thrombophlebitis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Collagen chain trimerization and Response to elevated platelet cytosolic Ca2+. The drugs Diclofenac and Heparin have been mentioned in the context of this disorder. Affiliated tissues include breast, liver and skin, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 74 Thrombophlebitis is a phlebitis (inflammation of a vein) related to a thrombus (blood clot). When it... more...

Related Diseases for Thrombophlebitis

Diseases related to Thrombophlebitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 698)
# Related Disease Score Top Affiliating Genes
1 femoral vein thrombophlebitis 34.7 PROC F2
2 lemierre's syndrome 33.5 SERPINC1 MTHFR F3 F2 CRP
3 varicose veins 32.2 VWF SERPINC1 PLAT MTHFR F5 F2
4 buerger disease 30.7 SERPINE1 MTHFR F2 APOH
5 cavernous sinus thrombosis 30.5 SERPINC1 F3 F2 CRP
6 lateral sinus thrombosis 30.3 SERPINC1 MTHFR F3 F2
7 dysfibrinogenemia, congenital 30.3 SERPINC1 PLAT F5 F2
8 porencephaly 30.2 MTHFR F5 F2
9 hemopericardium 30.2 PLG F3 F2
10 mesenteric vascular occlusion 30.2 MTHFR F7
11 hemorrhoid 30.2 F2 CRP ALB
12 abducens nerve disease 30.1 SERPINC1 F2 CRP
13 pyelonephritis 30.0 TGFB1 CRP ALB
14 protein c deficiency 30.0 SERPINE1 SERPINC1 PROC MTHFR F5 F2
15 pulmonary edema 29.9 SERPINC1 F2 CRP
16 pharyngitis 29.9 CRP CD40LG ALB
17 mastoiditis 29.9 SERPINC1 MTHFR F2 CRP CD40LG
18 thrombophilia due to thrombin defect 29.9 SERPINE1 SERPINC1 PROC PLAT MTHFR F8
19 polyarteritis nodosa 29.9 SELP CRP APOH
20 toxic shock syndrome 29.9 SERPINC1 F3 CRP CD40LG
21 paralytic ileus 29.8 F2 CRP ALB
22 infective endocarditis 29.8 SERPINE1 F2 CRP APOH
23 sagittal sinus thrombosis 29.8 SERPINC1 PLG F5 F3 F2
24 endocarditis 29.8 SERPINE1 SERPINC1 PLAT F2 CRP APOH
25 chickenpox 29.7 CRP CD40LG ALB
26 typhoid fever 29.7 F2 CRP CD40LG ALB
27 homocystinuria 29.7 SERPINC1 MTHFR F8 F5 ALB
28 myelitis 29.7 MTHFR CD40LG APOH
29 angiodysplasia 29.6 VWF F8 F3
30 liver cirrhosis 29.6 TGFB1 SERPINF2 SERPINC1 F3 F2 ALB
31 factor xii deficiency 29.6 VWF SERPINC1 F5 F3 APOH
32 otitis media 29.6 PLG CRP CD40LG ALB
33 hepatic infarction 29.6 SERPINC1 F3 F2 APOH ALB
34 necrotizing fasciitis 29.6 PLG CRP ALB
35 antithrombin iii deficiency 29.5 SERPINC1 PLG MTHFR F5 F3 F2
36 eclampsia 29.5 SERPINE1 SERPINC1 MTHFR F2 APOH ALB
37 urinary tract obstruction 29.5 TGFB1 SERPINE1 CRP ALB
38 protein-losing enteropathy 29.5 SERPINC1 CD40LG ALB
39 brain edema 29.5 PLAT CRP ALB
40 hyperuricemia 29.5 MTHFR CRP ALB
41 chronic venous insufficiency 29.4 TGFB1 SERPINE1 SELP PLAT F2 CRP
42 pneumonia 29.3 F3 F2 CRP CD40LG ALB
43 parotitis 29.3 CRP CD40LG ALB
44 cranial nerve palsy 29.3 CRP CD40LG ALB
45 sclerosing cholangitis 29.3 F2 CD40LG ALB
46 bronchopneumonia 29.3 CRP CD40LG ALB
47 pleural empyema 29.3 PLG F2 CRP CD40LG ALB
48 mediastinitis 29.3 F5 F3 F2 CRP ALB
49 dysentery 29.3 CRP CD40LG ALB
50 meningoencephalitis 29.3 CRP CD40LG ALB

Graphical network of the top 20 diseases related to Thrombophlebitis:



Diseases related to Thrombophlebitis

Symptoms & Phenotypes for Thrombophlebitis

MGI Mouse Phenotypes related to Thrombophlebitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.4 ALB APOH CD40LG CRP F2 F3
2 cardiovascular system MP:0005385 10.36 ALB CD40LG CRP F2 F3 F5
3 hematopoietic system MP:0005397 10.25 CD40LG F2 F3 F8 PLAT PLG
4 immune system MP:0005387 10.21 ALB CD40LG CRP F2 F3 F8
5 mortality/aging MP:0010768 10.11 ALB APOH CD40LG F2 F3 F5
6 integument MP:0010771 10.06 CD40LG F2 F3 F5 MTHFR PLAT
7 liver/biliary system MP:0005370 9.96 ALB F5 MTHFR PLG PROC PROS1
8 nervous system MP:0003631 9.77 CD40LG F2 F3 F5 MTHFR PLAT
9 respiratory system MP:0005388 9.23 F2 F3 PLAT PLG PROC SELP

Drugs & Therapeutics for Thrombophlebitis

Drugs for Thrombophlebitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 107)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
2
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
3
Tinzaparin Approved Phase 4 9041-08-1, 9005-49-6 25244225
4
Ibuprofen Approved Phase 4 15687-27-1 3672
5
Dalteparin Approved Phase 4 9005-49-6
6
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
7
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
8
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
9
Etomidate Approved Phase 4 33125-97-2 36339 667484
10
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
11
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
12
Bisoprolol Approved Phase 4 66722-44-9 2405
13 Anti-Inflammatory Agents Phase 4
14 Analgesics Phase 4
15 Analgesics, Non-Narcotic Phase 4
16 Cyclooxygenase Inhibitors Phase 4
17 Antirheumatic Agents Phase 4
18 Anti-Inflammatory Agents, Non-Steroidal Phase 4
19 Fibrinolytic Agents Phase 4
20 Anticoagulants Phase 4
21 Salicylates Phase 4
22 Heparinoids Phase 4
23 Anesthetics Phase 4
24 Heparin, Low-Molecular-Weight Phase 4
25 calcium heparin Phase 4
26 Anesthetics, General Phase 4
27 Hypnotics and Sedatives Phase 4
28 Anesthetics, Intravenous Phase 4
29 Adrenergic beta-1 Receptor Antagonists Phase 4
30 Antihypertensive Agents Phase 4
31 Adrenergic Antagonists Phase 4
32 Sympatholytics Phase 4
33 Adrenergic Agents Phase 4
34 Hydrocortisone 17-butyrate 21-propionate Phase 4
35 Adrenergic beta-Antagonists Phase 4
36 Hydrocortisone hemisuccinate Phase 4
37 Neurotransmitter Agents Phase 4
38 Pharmaceutical Solutions Phase 4
39
Amiodarone Approved, Investigational Phase 3 1951-25-3 2157
40
Fondaparinux Approved, Investigational Phase 3 104993-28-4
41
Rutin Approved, Experimental, Investigational Phase 3 153-18-4 5280805
42
Parnaparin Approved, Investigational Phase 3 9005-49-6
43
Tranexamic Acid Approved Phase 3 1197-18-8 5526
44 Sodium Channel Blockers Phase 3
45 Cytochrome P-450 Enzyme Inhibitors Phase 3
46 Anti-Arrhythmia Agents Phase 3
47 Vasodilator Agents Phase 3
48 Potassium Channel Blockers Phase 3
49 Diuretics, Potassium Sparing Phase 3
50 Cytochrome P-450 CYP3A Inhibitors Phase 3

Interventional clinical trials:

(show top 50) (show all 56)
# Name Status NCT ID Phase Drugs
1 A One Week, Double-Blind, Adaptive, Randomized, Multicenter Study to Compare the Efficacy, Safety and Tolerability of Topical Diclofenac Gel Versus Placebo in Patients With Superficial Thrombophlebitis Completed NCT00377806 Phase 4 Diclofenac gel
2 Evaluate the Efficacy and Safety of Esarin Gel in the Treatment of Chronic Venous Insufficiency or Varicose Vein Combine With Superficial Vein Thrombophlebitis in Outpatient Completed NCT02346058 Phase 4 Esarin Gel
3 Management of Superficial Thrombophlebitis Completed NCT00264381 Phase 4 Dalteparin sodium injection
4 Prospective, Randomized, Double-blinded Trial of the Efficacy and Safety of Different Doses and Duration of Low Molecular Weight Heparin (Dalteparin) in Superficial Vein Thrombosis Completed NCT01245998 Phase 4 Dalteparin;Dalteparin
5 Randomised, Prospective Study of the Use of In-Line Filtration on the Reduction of Complication Rate in Critically Ill Children Completed NCT00209768 Phase 4
6 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion ("Yuria-Pharm"), in Comparison With Ringer's Lactate,Solution for Infusion, in a Complex Therapy of Pneumonia. Completed NCT03824457 Phase 4 Rheosorbilact®;Ringer lactate
7 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion, in Comparison With Ringer's Lactate,Solution for Infusion, in a Complex Therapy of Peritonitis. Completed NCT03771170 Phase 4 Rheosorbilact®;Ringer lactate
8 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion, in Comparison With Ringer's Lactate, Solution for Infusion, in a Complex Therapy of Sepsis. Completed NCT03764085 Phase 4 Rheosorbilact®;Ringer lactate
9 Comparison of Induction Characteristics of Two Anaesthetic Agents-Etomidate Lipuro and Propofol Completed NCT02807610 Phase 4 Inj Etomidate;Injection Propofol;Placebo for Propofol
10 Bisoprolol Versus Corticosteroid and Bisoprolol Combination for Prophylaxis Against Atrial Fibrillation After on Pump Coronary Artery Bypass Surgery Completed NCT03800264 Phase 4 Bisoprolol
11 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion ("Yuria-Pharm"), in Comparison With Ringer's Lactate,Solution for Infusion, in a Complex Therapy of Burns Recruiting NCT04152096 Phase 4 Rheosorbilact®;Ringer lactate
12 The Effect of Intravenous vs. Oral Administration of Amiodarone on the Incidence Rate of Phlebitis Among Patients With Recent Onset of Atrial Fibrillation (AF) Unknown status NCT01817439 Phase 3 Amiodarone
13 An International, Multicentre, Randomised, Double-blind, Placebo-controlled, Two-parallel Group, Phase III Study to Evaluate the Efficacy and Safety of ARIXTRA (2.5mg Subcutaneously) for the Treatment of Patients With Acute Symptomatic Isolated Superficial Thrombophlebitis of the Lower Limbs to Prevent Thromboembolic Complications Completed NCT00443053 Phase 3 Fondaparinux 2.5mg or placebo
14 Efficacy and Tolerability of Hirudoid Cream in Prophylaxis and Treatment of Superficial Infusion Thrombophlebitis Completed NCT01943006 Phase 3 Hirudoid cream 0.3 % Mucopolysaccharide polysulfate;Placebo cream without active substance
15 Phlogenzym® in Patients With Acute Thrombophlebitis - Efficacy and Tolerance - Randomised Double-blind Study Phase III With Parallel Groups vs. Placebo According to the Guidelines of Good Clinical Practice (GCP) Completed NCT03470337 Phase 3 Phlogenzym
16 Randomized Clinical Study of Different Treatment Doses and Duration of Low Molecular Weight Heparin (Parnaparin) in Superficial Vein Thrombosis Completed NCT00362947 Phase 3 LMWH parnaparin subcutaneously
17 Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF) Completed NCT00000517 Phase 3 warfarin
18 ATERO : A Randomised Study With Tranexamic Acid in Epistaxis of Rendu Osler Syndrome. Beneficial or Iatrogenic Effects. Completed NCT00355108 Phase 3 tranexamic acid
19 Prolongation of the Interval Between Prothrombin Time Tests in Stable Patients II (the PRINT II Study): a Randomized Controlled, Non-inferiority Trial Comparing 4-weekly With 12-weekly Testing and Dose-assessment Withdrawn NCT01654042 Phase 3
20 A Prospective Double Blind Randomized Controlled Trial Of Electrocoagulation Versus Radiofrequency Treatment Of The Great Saphenous Vein In Patients With Varicose Veins. Unknown status NCT02139085 Phase 2
21 Multicentered, Randomized Study of Safety and Efficacy of Whole-body Vibration as add-on to Standard Pharmacological Treatment of Osteoporosis in Post-menopausal Women Completed NCT01415050 Phase 2
22 Analgesic Efficacy of Pulsed Radiofrequency in Non-cyclic Mastalgia Completed NCT03715413 Phase 2 Tamoxifen
23 A Randomized Double Blind Placebo Controlled Trial to Assess the Safety and Efficacy of Intravenous Immunoglobulin (IVIG) in Children With Japanese Encephalitis in Nepal Completed NCT01856205 Phase 2 Intravenous immunoglobulin [ImmunoRel™ (batch 20081217)]
24 Tocilizumab for the Treatment of Behcet's Syndrome Terminated NCT01693653 Phase 2 Tocilizumab
25 Phase II Randomized Trial With A Modified Dose & Schedule of Subcutaneously Administered Azacitidine & Erythropoietin v Azacitidine Alone in Patients With Low-Risk Myelodysplastic Syndromes (Less Than 11% Marrow & Peripheral Blood Blasts) Terminated NCT00379912 Phase 2 Azacitidine;Erythropoietin;Azacitidine (Monotherapy)
26 Treatment of Acute Deep Vein Thrombosis of the Lower Extremity With Intraclot, Pulse-Sprayed Recombinant Tissue Plasminogen Activator, Plus Heparin and Warfarin: A Pilot Study Completed NCT00001713 Phase 1 Recombinant Tissue Plasminogen Activator;Heparin;Warfarin
27 A Phase I Study of the Adam-10 Inhibitor, INCB7839 in Children With Recurrent/Progressive High-Grade Gliomas to Target Microenvironmental Neuroligin-3 Recruiting NCT04295759 Phase 1 INCB7839
28 Prophylactic Antibiotics After Cesarean Recruiting NCT03187106 Phase 1 Cephalexin;Placebo;Metronidazole
29 Phase I Trial of Intravenous Fenretinide (4-HPR) Plus Intravenous Safingol for Patients With Relapsed Malignancies Recruiting NCT01553071 Phase 1 Fenretinide (4-HPR) plus Intravenous Safingol
30 Evaluation of Peripheral Intravenous Catheter and Urinary Catheters Present on Admission to the "Maladies Infectieuses aiguës" Department. Unknown status NCT03329768
31 Prospective Observational Study on Picclines' Complications at Brest Hospital Unknown status NCT03017911
32 Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices; Multicenter Study Unknown status NCT02256046
33 Treatment of Chorioamnionitis After Delivery Unknown status NCT00814905 saline;ampicillin gentamicin;Ampicillin gentamicin clindamycin;ampicillin gentamicin clindamycin
34 Effectiveness of Physical Exercise With Flow Restriction on the Diameter and the Flow of the Blood Vessels of the Forearm in Chronic Kidney Disease: a Randomized Clinical Trial Unknown status NCT02619968
35 Superficial Thrombophlebitis and Venous Thromboembolism: A Large Prospective Epidemiological Study Completed NCT00818688
36 Evaluation of Clinical Characteristics of Endovenous Sclerotherapy of Varicose Veins Completed NCT00954980
37 Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression Stockings: A Randomized Pilot Study Completed NCT01793194
38 Comparison Between Transradial and Transfemoral Routes of Coronary Angiography and Interventions Completed NCT02983721
39 Trans-perineal Pumpkin Seeds Phonophoresis as an Adjunct Treatment for Chronic Non-bacterial Prostatitis Completed NCT03461263
40 Assessing Efficacy of Axillary Web Syndrome Treatment Completed NCT03284008
41 COVID-19 and Deep Venous Thrombosis: a Cross-sectional Study Completed NCT04338932
42 Effect of Transcutaneous Electrical Nerve Stimulation on Pain Intensity of Patients With Hip Arthroplasty: A Randomized Control Trial Completed NCT03534999
43 Endovenous Laser Ablation of the Great Saphenous Vein Comparing 1920-nm and 1470-nm Diode Laser Completed NCT02504684
44 The Effect of Intraoperative Sequential Compression Devices on Fibrinolysis in Plastic Surgery Outpatients: A Randomized Trial Completed NCT03821597
45 Thrombotic Complications After Central Venous Catheterization: a Prospective Observational Study Recruiting NCT04302376
46 HARapan kiTa ECP (External Counter Pulsation) Study HARTEC Study Recruiting NCT03991871
47 Characteristics, Complications and Perinatal Outcomes in Placenta Previa Women: a Prospective, Matched Case-control Study Recruiting NCT03774667
48 Randomized Comparative Evaluation of Midline Catheters for Thrombophlebitis Recruiting NCT03725293
49 Novel Strategy to Encourage Early Removal of Central Venous Catheters Recruiting NCT04136561
50 Role of Intravascular Ultrasound(IVUS) in Management of Acute and Chronic Iliocaval Obstruction Recruiting NCT04024215

Search NIH Clinical Center for Thrombophlebitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Dalteparin
Dalteparin Sodium
Enoxaparin
heparin
heparin calcium
heparin sodium
HEPARIN SODIUM (BEEF LUNG)
heparin sodium, bovine
heparin sodium, porcine
Tolazoline
Tolazoline Hydrochloride
Warfarin
Warfarin Sodium
WARFARIN SODIUM ISOPROPANOL COMPLEX

Cochrane evidence based reviews: thrombophlebitis

Genetic Tests for Thrombophlebitis

Genetic tests related to Thrombophlebitis:

# Genetic test Affiliating Genes
1 Thrombophlebitis 29

Anatomical Context for Thrombophlebitis

MalaCards organs/tissues related to Thrombophlebitis:

40
Breast, Liver, Skin, Lung, Testes, Brain, Kidney

Publications for Thrombophlebitis

Articles related to Thrombophlebitis:

(show top 50) (show all 5547)
# Title Authors PMID Year
1
Continuous infusion of intermediate-purity factor VIII in haemophilia A patients undergoing elective surgery. 54 61
10444285 1999
2
[Thrombophlebitis in a patient with acute Q fever and anticardiolipin antibodies]. 61 54
9139149 1997
3
Effect of recombinant erythropoietin therapy on autoimmunity in systemic lupus erythematosus. 54 61
8023821 1994
4
The increased recurrence rate of liver abscess caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae. 61
32062726 2020
5
Cavernous Thrombophlebitis Secondary to Cavernous Internal Carotid Mycotic Aneurysm. 61
32549947 2020
6
May Thurner syndrome: description of a case with unusual clinical onset. 61
32577934 2020
7
Superficial thrombophlebitis in a patient with COVID 19: Heparin treatment after evaluation of D - Dimer: COVID 19 and Superficial thrombophlebitis. 61
32500589 2020
8
Pulmonary embolism caused by postpartum ovarian vein thrombophlebitis after vaginal delivery: Case report and brief review of the literature. 61
31930727 2020
9
Complications of peripherally inserted central catheters in pregnancy: a systematic review and meta-analysis. 61
32441173 2020
10
Management and outcomes of pediatric septic thrombophlebitis: a case series. 61
32138584 2020
11
Impact of concomitant deep or superficial venous thrombosis of the legs on survival of patients with pulmonary embolism. 61
32445886 2020
12
Foam sclerotherapy compared with liquid sclerotherapy for the treatment of lower extremity varicose veins: A protocol for systematic review and meta analysis. 61
32481409 2020
13
Presentation and Management of Klippel-Trenaunay Syndrome: A Review of Available Data. 61
32528762 2020
14
Spinal cord infarction during venoarterial-extracorporeal membrane oxygenation support. 61
32474793 2020
15
[Gynecological Lemierre's syndrome: A case report and literature review]. 61
32371121 2020
16
A forensic case of erosive cystitis and septic pulmonary embolism: is there a correlation? 61
32323705 2020
17
Results of polidocanol endovenous microfoam in clinical practice. 61
32353594 2020
18
Pattern of pulmonary vasculitis and major vascular involvement in Hughes-Stovin syndrome (HSS): brief report of eight cases. 61
31853734 2020
19
A Rare Case of Lemierre's Syndrome Caused by Streptococcus Intermedius, Presenting as an Epidural Abscess. 61
32455086 2020
20
Anaerobic Necrotizing Pneumonia: Another Potential Life-threatening Complication of Vaping? 61
32132153 2020
21
Magnetic resonance imaging for diagnosis of recurrent ipsilateral deep vein thrombosis. 61
32016390 2020
22
Association of Treatment of Chorioamnionitis with Non-Beta Lactam Antibiotics and Postcesarean Infectious Morbidity. 61
31600797 2020
23
Lemierre's syndrome: A forgotten and re-emerging infection. 61
32303484 2020
24
Peripheral Vein Thrombophlebitis in the Upper Extremity: A Systematic Review of a Frequent and Important Problem. 61
31606488 2020
25
Variations in Incidence of Venous Thromboembolism in Low-, Middle- and High-Income Countries. 61
32142099 2020
26
Safety and effectiveness of percutaneous sclerotherapy for venous disorders of the labia majora in patients with vascular malformations. 61
32199800 2020
27
A case of liver abscesses and porto-enteric fistula caused by an ingested toothpick: A review of the distinctive clinical and imaging features. 61
31956387 2020
28
Guidelines for the treatment of skin and mucosal lesions in Behçet's disease: A secondary publication. 61
31907947 2020
29
A Lemierre-like syndrome caused by Staphylococcus aureus: an emerging disease. 61
31749395 2020
30
Outcomes of Elective Total Hip Arthroplasty in Nonagenarians and Centenarians. 61
32312644 2020
31
Fusobacterium necrophorum Septicemia Leading to Lemierre's Syndrome in an Immunocompetent Individual: A Case Report. 61
32257727 2020
32
Lemierre's syndrome caused by Streptococcus pyogenes in an elderly woman. 61
32055760 2020
33
A unique case of Lemierre's syndrome status post blunt cervical trauma. 61
32228176 2020
34
Mondor's Disease: A Rare Cause of Chest Pain in the Emergency Department. 61
32190472 2020
35
Trends in knee arthroscopy utilization: a gap in knowledge translation. 61
31359100 2020
36
Abdominal computed tomography (CT) scan in the evaluation of refractory puerperal fever: impact on management. 61
29973085 2020
37
An Unusual Case of Modified Lemierre's Syndrome Caused by Staphylococcus aureus Cellulitis. 61
32008035 2020
38
Thrombophlebitis Migrans. 61
32181733 2020
39
The role of anticoagulation in pylephlebitis: a retrospective examination of characteristics and outcomes. 61
31493290 2020
40
Extra-cardiac endovascular infections in the critically ill. 61
31745594 2020
41
Isolated Superficial Dorsal Penile Vein Thrombosis due to Scabies Infestation. 61
32036835 2020
42
Effect of miR-223 on thrombophlebitis rats through regulating Toll-like receptor signaling pathway. 61
32141571 2020
43
[Cerebral thrombophlebitis: complication of frontotemporoparietal cellulitis in a child victim of human bite]. 61
32341735 2020
44
First case report of nematode parasitic myelopathy in a wild feline in Brazil. 61
32049140 2020
45
Safety of simultaneous versus staged bilateral opening-wedge high tibial osteotomy with locked plate and immediate weight bearing. 61
31385014 2020
46
A rare case of mesenteric vessel thrombosis post caesarian section-An underdiagnosed entity. 61
32169825 2020
47
Validation of ICD-10 codes shows intracranial venous thrombosis incidence to be higher than previously reported. 61
30563370 2020
48
Ultrasound- and fluoroscopy-guided foam sclerotherapy for lower extremity venous ulcers. 61
31917182 2020
49
Cerebral Infarction Followed by Myocardial Infarction in a Young Adult with Protein C and S Deficiency. 61
32089972 2020
50
Case of internal jugular vein thrombosis and fever: Lemierre's syndrome or Trousseau's syndrome? 61
32110528 2020

Variations for Thrombophlebitis

Expression for Thrombophlebitis

Search GEO for disease gene expression data for Thrombophlebitis.

Pathways for Thrombophlebitis

Pathways related to Thrombophlebitis according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.73 SERPINC1 PROS1 PROC F8 F7 F5
2
Show member pathways
12.63 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 SELP
3
Show member pathways
12.19 SERPINE1 PLG PLAT MTHFR F7 F2
4
Show member pathways
12.17 VWF SERPINF2 SERPINE1 SERPINC1 PROS1 PROC
5
Show member pathways
12.08 TGFB1 SELP PROS1 PROC F2
6 11.93 VWF SERPINF2 SERPINE1 SERPINC1 PROS1 PROC
7
Show member pathways
11.79 PROS1 PROC F7 F2
8 11.66 VWF TGFB1 F3
9 11.49 SERPINE1 PLG PLAT
10 11.39 TGFB1 SELP CD40LG
11 11.36 TGFB1 PLG PLAT
12 11.33 SELP PLG PLAT
13 10.85 PROS1 PROC F7 F2
14 10.74 SERPINF2 SERPINE1 PLG PLAT

GO Terms for Thrombophlebitis

Cellular components related to Thrombophlebitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 10.18 VWF SERPINF2 SERPINE1 SERPINC1 PROS1 PLG
2 extracellular region GO:0005576 10.11 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 PROS1
3 collagen-containing extracellular matrix GO:0062023 10 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 PLG
4 cell surface GO:0009986 9.98 TGFB1 SERPINF2 PLG PLAT F3 CD40LG
5 endoplasmic reticulum lumen GO:0005788 9.91 SERPINC1 PROC F8 F7 F5 F2
6 blood microparticle GO:0072562 9.87 TGFB1 SERPINF2 SERPINC1 PROS1 PLG F2
7 Golgi lumen GO:0005796 9.8 TGFB1 PROS1 PROC F7 F2
8 platelet alpha granule lumen GO:0031093 9.61 VWF TGFB1 SERPINF2 SERPINE1 PROS1 PLG
9 extracellular space GO:0005615 9.58 TGFB1 SERPINF2 SERPINE1 SERPINC1 SELP PROS1
10 serine-type peptidase complex GO:1905286 9.46 F7 F3

Biological processes related to Thrombophlebitis according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.95 SERPINC1 PROC PLG F5 F2 ALB
2 ER to Golgi vesicle-mediated transport GO:0006888 9.93 PROS1 PROC F8 F7 F5 F2
3 leukocyte migration GO:0050900 9.9 TGFB1 SELP PROS1 F2
4 response to hypoxia GO:0001666 9.88 TGFB1 PLAT MTHFR F7
5 negative regulation of endopeptidase activity GO:0010951 9.88 SERPINF2 SERPINE1 SERPINC1 PROS1
6 hemostasis GO:0007599 9.85 VWF SERPINC1 PROS1 PROC PLG F8
7 platelet activation GO:0030168 9.84 VWF F8 F2 CD40LG
8 acute-phase response GO:0006953 9.8 SERPINF2 F8 F2 CRP
9 response to wounding GO:0009611 9.78 VWF TGFB1 F2
10 blood coagulation, intrinsic pathway GO:0007597 9.73 VWF F8 F2 APOH
11 fibrinolysis GO:0042730 9.73 SERPINF2 SERPINE1 PROS1 PLG PLAT F2
12 negative regulation of fibrinolysis GO:0051918 9.72 SERPINF2 SERPINE1 PLG F2 APOH
13 negative regulation of blood coagulation GO:0030195 9.71 SERPINE1 PROS1 PROC APOH
14 positive regulation of collagen biosynthetic process GO:0032967 9.7 TGFB1 SERPINF2 F2
15 blood coagulation GO:0007596 9.7 VWF SERPINC1 PROS1 PROC PLG PLAT
16 regulation of blood coagulation GO:0030193 9.69 SERPINC1 F2 APOH
17 positive regulation of blood coagulation GO:0030194 9.67 SERPINE1 F7 F2 APOH
18 positive regulation of positive chemotaxis GO:0050927 9.62 F7 F3
19 plasminogen activation GO:0031639 9.62 PLAT APOH
20 response to cholesterol GO:0070723 9.61 TGFB1 F7
21 negative regulation of plasminogen activation GO:0010757 9.59 SERPINF2 SERPINE1
22 trans-synaptic signaling by BDNF, modulating synaptic transmission GO:0099183 9.57 PLG PLAT
23 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.56 F7 F3
24 blood coagulation, extrinsic pathway GO:0007598 9.55 F7 F3
25 platelet degranulation GO:0002576 9.36 VWF TGFB1 SERPINF2 SERPINE1 SELP PROS1

Molecular functions related to Thrombophlebitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 10.39 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 SELP
2 calcium ion binding GO:0005509 9.88 SELP PROS1 PROC F7 F2 CRP
3 peptidase activity GO:0008233 9.85 PROC PLG PLAT F7 F2
4 signaling receptor binding GO:0005102 9.72 SERPINE1 PLG PLAT F7 F2
5 heparin binding GO:0008201 9.56 SERPINC1 SELP F2 APOH
6 serine-type peptidase activity GO:0008236 9.55 PROC PLG PLAT F7 F2
7 copper ion binding GO:0005507 9.54 F8 F5 ALB
8 protease binding GO:0002020 9.35 VWF SERPINF2 SERPINE1 SERPINC1 F3
9 serine-type endopeptidase activity GO:0004252 9.1 PROC PLG PLAT F7 F3 F2

Sources for Thrombophlebitis

3 CDC
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
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30 HMDB
31 HPO
32 ICD10
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61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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