MCID: THR016
MIFTS: 51

Thrombophlebitis

Categories: Blood diseases, Cardiovascular diseases

Aliases & Classifications for Thrombophlebitis

MalaCards integrated aliases for Thrombophlebitis:

Name: Thrombophlebitis 12 29 54 43 15 71
Phlebitis and Thrombophlebitis of Superficial Vessels of Lower Extremities 12 32
Thrombophlebitis of Superficial Veins of Lower Extremity 12
Thrombophlebitis of a Superficial Leg Vein 12
Superficial Thrombophlebitis of Leg 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3875
ICD9CM 34 451.0
MeSH 43 D013924
NCIt 49 C3410
SNOMED-CT 67 40283005 64156001
ICD10 32 I80.0
UMLS 71 C0040046 C0265057

Summaries for Thrombophlebitis

Disease Ontology : 12 A phlebitis that results from a blood clot in the vessel.

MalaCards based summary : Thrombophlebitis, also known as phlebitis and thrombophlebitis of superficial vessels of lower extremities, is related to femoral vein thrombophlebitis and lemierre's syndrome. An important gene associated with Thrombophlebitis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Collagen chain trimerization and Response to elevated platelet cytosolic Ca2+. The drugs Diclofenac and Heparin have been mentioned in the context of this disorder. Affiliated tissues include breast, lung and liver, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 74 Thrombophlebitis is a phlebitis (inflammation of a vein) related to a thrombus (blood clot). When it... more...

Related Diseases for Thrombophlebitis

Diseases related to Thrombophlebitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 689)
# Related Disease Score Top Affiliating Genes
1 femoral vein thrombophlebitis 34.7 PROC F2
2 lemierre's syndrome 33.6 MTHFR F3 F2 CRP
3 varicose veins 32.1 VWF SERPINC1 PLAT MTHFR F5 F2
4 cavernous sinus thrombosis 30.8 SERPINC1 F2 CRP
5 lateral sinus thrombosis 30.7 SERPINC1 MTHFR F2
6 buerger disease 30.7 SERPINE1 MTHFR F2 APOH
7 mastoiditis 30.5 SERPINC1 MTHFR F2 CRP
8 dysfibrinogenemia, congenital 30.3 SERPINC1 PLAT F5 F2
9 porencephaly 30.2 MTHFR F5 F2
10 polyarteritis nodosa 30.2 SELP CRP APOH
11 hemopericardium 30.1 PLG F3 F2
12 hemorrhoid 29.9 F2 CRP ALB
13 protein c deficiency 29.9 SERPINE1 SERPINC1 PROC MTHFR F5 F2
14 pulmonary edema 29.9 SERPINC1 F2 CRP
15 antithrombin iii deficiency 29.8 SERPINC1 PLG MTHFR F5 F2 APOH
16 homocystinuria 29.8 SERPINC1 MTHFR F5 ALB
17 thrombophilia due to thrombin defect 29.7 SERPINE1 SERPINC1 PROC PLAT MTHFR F8
18 sagittal sinus thrombosis 29.7 SERPINC1 PLG F5 F3 F2
19 eclampsia 29.6 SERPINE1 SERPINC1 MTHFR F2 ALB
20 paralytic ileus 29.6 F2 CRP ALB
21 angiodysplasia 29.6 VWF F8 F3
22 klebsiella pneumonia 29.6 PLAT CRP ALB
23 toxic shock syndrome 29.6 SERPINC1 F3 CRP CD40LG
24 factor xii deficiency 29.6 VWF SERPINC1 F5 F3 APOH
25 endocarditis 29.5 SERPINE1 SERPINC1 PLAT F2 CRP APOH
26 arteriosclerosis 29.4 SERPINE1 SERPINC1 SELP F3 CRP
27 myelitis 29.4 MTHFR CD40LG APOH
28 chronic venous insufficiency 29.4 TGFB1 SERPINE1 SELP PLAT MTHFR F2
29 mediastinitis 29.4 F5 F2 CRP ALB
30 hepatic infarction 29.4 SERPINC1 F3 F2 APOH ALB
31 liver cirrhosis 29.4 TGFB1 SERPINF2 SERPINC1 F3 F2 ALB
32 post-thrombotic syndrome 29.3 SERPINE1 SERPINC1 PLG PLAT F8 F5
33 chickenpox 29.3 CRP CD40LG ALB
34 typhoid fever 29.3 F2 CRP CD40LG ALB
35 urinary tract obstruction 29.3 TGFB1 SERPINE1 CRP ALB
36 maxillary sinusitis 29.2 SELP CRP CD40LG
37 brain edema 29.2 PLAT CRP ALB
38 otitis media 29.2 PLG CRP CD40LG ALB
39 budd-chiari syndrome 29.1 SERPINC1 MTHFR F7 F5 F3 F2
40 necrotizing fasciitis 29.0 PLG F3 CRP ALB
41 pleural empyema 29.0 PLG CRP CD40LG ALB
42 purpura fulminans 29.0 SERPINF2 SERPINC1 PROS1 PROC F5 F3
43 vasculitis 28.9 VWF SELP CRP CD40LG APOH
44 syphilis 28.9 CRP CD40LG APOH ALB
45 parotitis 28.9 CRP CD40LG ALB
46 cranial nerve palsy 28.9 CRP CD40LG ALB
47 intracranial hypertension 28.9 SERPINE1 SERPINC1 MTHFR F5 F3 F2
48 sclerosing cholangitis 28.9 F2 CD40LG ALB
49 bronchopneumonia 28.9 CRP CD40LG ALB
50 end stage renal failure 28.9 TGFB1 SELP CRP ALB

Graphical network of the top 20 diseases related to Thrombophlebitis:



Diseases related to Thrombophlebitis

Symptoms & Phenotypes for Thrombophlebitis

MGI Mouse Phenotypes related to Thrombophlebitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.4 ALB APOH CD40LG CRP F2 F3
2 cardiovascular system MP:0005385 10.36 ALB CD40LG CRP F2 F3 F5
3 hematopoietic system MP:0005397 10.25 CD40LG F2 F3 F8 PLAT PLG
4 immune system MP:0005387 10.21 ALB CD40LG CRP F2 F3 F8
5 mortality/aging MP:0010768 10.11 ALB APOH CD40LG F2 F3 F5
6 integument MP:0010771 10.06 CD40LG F2 F3 F5 MTHFR PLAT
7 liver/biliary system MP:0005370 9.96 ALB F5 MTHFR PLG PROC PROS1
8 nervous system MP:0003631 9.77 CD40LG F2 F3 F5 MTHFR PLAT
9 respiratory system MP:0005388 9.23 F2 F3 PLAT PLG PROC SELP

Drugs & Therapeutics for Thrombophlebitis

Drugs for Thrombophlebitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 120)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
2
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
3
Ibuprofen Approved Phase 4 15687-27-1 3672
4
Dalteparin Approved Phase 4 9005-49-6
5
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
6
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
7
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
8
Etomidate Approved Phase 4 33125-97-2 36339 667484
9
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
10
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
11
Bisoprolol Approved Phase 4 66722-44-9 2405
12
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
13 Anti-Inflammatory Agents Phase 4
14 Anti-Inflammatory Agents, Non-Steroidal Phase 4
15 Analgesics, Non-Narcotic Phase 4
16 Cyclooxygenase Inhibitors Phase 4
17 Antirheumatic Agents Phase 4
18 Analgesics Phase 4
19 Fibrinolytic Agents Phase 4
20 Heparinoids Phase 4
21 Salicylates Phase 4
22 Anesthetics Phase 4
23 Heparin, Low-Molecular-Weight Phase 4
24 calcium heparin Phase 4
25 Calcium, Dietary Phase 4
26 Tranquilizing Agents Phase 4
27 Anti-Anxiety Agents Phase 4
28 Neurotransmitter Agents Phase 4
29 Narcotics Phase 4
30 Hypnotics and Sedatives Phase 4
31 Psychotropic Drugs Phase 4
32 GABA Agents Phase 4
33 Anesthetics, General Phase 4
34 Adjuvants, Anesthesia Phase 4
35 Analgesics, Opioid Phase 4
36 GABA Modulators Phase 4
37 Anesthetics, Intravenous Phase 4
38 Central Nervous System Depressants Phase 4
39 Antihypertensive Agents Phase 4
40 Hydrocortisone hemisuccinate Phase 4
41 Hydrocortisone-17-butyrate Phase 4
42 Hydrocortisone 17-butyrate 21-propionate Phase 4
43 Adrenergic beta-1 Receptor Antagonists Phase 4
44 Adrenergic Antagonists Phase 4
45 Adrenergic beta-Antagonists Phase 4
46 Autonomic Agents Phase 4
47 Sympatholytics Phase 4
48 Adrenergic Agents Phase 4
49 Pharmaceutical Solutions Phase 4
50
Amiodarone Approved, Investigational Phase 3 1951-25-3 2157

Interventional clinical trials:

(show top 50) (show all 53)
# Name Status NCT ID Phase Drugs
1 A One Week, Double-Blind, Adaptive, Randomized, Multicenter Study to Compare the Efficacy, Safety and Tolerability of Topical Diclofenac Gel Versus Placebo in Patients With Superficial Thrombophlebitis Completed NCT00377806 Phase 4 Diclofenac gel
2 Evaluate the Efficacy and Safety of Esarin Gel in the Treatment of Chronic Venous Insufficiency or Varicose Vein Combine With Superficial Vein Thrombophlebitis in Outpatient Completed NCT02346058 Phase 4 Esarin Gel
3 Management of Superficial Thrombophlebitis Completed NCT00264381 Phase 4 Dalteparin sodium injection
4 Prospective, Randomized, Double-blinded Trial of the Efficacy and Safety of Different Doses and Duration of Low Molecular Weight Heparin (Dalteparin) in Superficial Vein Thrombosis Completed NCT01245998 Phase 4 Dalteparin;Dalteparin
5 Randomised, Prospective Study of the Use of In-Line Filtration on the Reduction of Complication Rate in Critically Ill Children Completed NCT00209768 Phase 4
6 Comparison of Induction Characteristics of Two Anaesthetic Agents-Etomidate Lipuro and Propofol Completed NCT02807610 Phase 4 Inj Etomidate;Injection Propofol;Placebo for Propofol
7 Bisoprolol Versus Corticosteroid and Bisoprolol Combination for Prophylaxis Against Atrial Fibrillation After on Pump Coronary Artery Bypass Surgery Completed NCT03800264 Phase 4 Bisoprolol
8 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion, in Comparison With Ringer's Lactate,Solution for Infusion, in a Complex Therapy of Peritonitis. Recruiting NCT03771170 Phase 4 Rheosorbilact®;Ringer lactate
9 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion, in Comparison With Ringer's Lactate, Solution for Infusion, in a Complex Therapy of Sepsis. Recruiting NCT03764085 Phase 4 Rheosorbilact®;Ringer lactate
10 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion ("Yuria-Pharm"), in Comparison With Ringer's Lactate,Solution for Infusion, in a Complex Therapy of Pneumonia. Recruiting NCT03824457 Phase 4 Rheosorbilact®;Ringer lactate
11 Open-label, Randomized, Controlled, With Blind Assessor, Study to Assess Efficacy and Safety of Rheosorbilact®, Solution for Infusion ("Yuria-Pharm"), in Comparison With Ringer's Lactate,Solution for Infusion, in a Complex Therapy of Burns Recruiting NCT04152096 Phase 4 Rheosorbilact®;Ringer lactate
12 The Effect of Intravenous vs. Oral Administration of Amiodarone on the Incidence Rate of Phlebitis Among Patients With Recent Onset of Atrial Fibrillation (AF) Unknown status NCT01817439 Phase 3 Amiodarone
13 An International, Multicentre, Randomised, Double-blind, Placebo-controlled, Two-parallel Group, Phase III Study to Evaluate the Efficacy and Safety of ARIXTRA (2.5mg Subcutaneously) for the Treatment of Patients With Acute Symptomatic Isolated Superficial Thrombophlebitis of the Lower Limbs to Prevent Thromboembolic Complications Completed NCT00443053 Phase 3 Fondaparinux 2.5mg or placebo
14 Efficacy and Tolerability of Hirudoid Cream in Prophylaxis and Treatment of Superficial Infusion Thrombophlebitis Completed NCT01943006 Phase 3 Hirudoid cream 0.3 % Mucopolysaccharide polysulfate;Placebo cream without active substance
15 Phlogenzym® in Patients With Acute Thrombophlebitis - Efficacy and Tolerance - Randomised Double-blind Study Phase III With Parallel Groups vs. Placebo According to the Guidelines of Good Clinical Practice (GCP) Completed NCT03470337 Phase 3 Phlogenzym
16 Randomized Clinical Study of Different Treatment Doses and Duration of Low Molecular Weight Heparin (Parnaparin) in Superficial Vein Thrombosis Completed NCT00362947 Phase 3 LMWH parnaparin subcutaneously
17 Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF) Completed NCT00000517 Phase 3 warfarin
18 ATERO : A Randomised Study With Tranexamic Acid in Epistaxis of Rendu Osler Syndrome. Beneficial or Iatrogenic Effects. Completed NCT00355108 Phase 3 tranexamic acid
19 Prolongation of the Interval Between Prothrombin Time Tests in Stable Patients II (the PRINT II Study): a Randomized Controlled, Non-inferiority Trial Comparing 4-weekly With 12-weekly Testing and Dose-assessment Withdrawn NCT01654042 Phase 3
20 A Prospective Double Blind Randomized Controlled Trial Of Electrocoagulation Versus Radiofrequency Treatment Of The Great Saphenous Vein In Patients With Varicose Veins. Unknown status NCT02139085 Phase 2
21 Analgesic Efficacy of Pulsed Radiofrequency in Non-cyclic Mastalgia Completed NCT03715413 Phase 2 Tamoxifen
22 Multicentered, Randomized Study of Safety and Efficacy of Whole-body Vibration as add-on to Standard Pharmacological Treatment of Osteoporosis in Post-menopausal Women Completed NCT01415050 Phase 2
23 A Randomized Double Blind Placebo Controlled Trial to Assess the Safety and Efficacy of Intravenous Immunoglobulin (IVIG) in Children With Japanese Encephalitis in Nepal Completed NCT01856205 Phase 2 Intravenous immunoglobulin [ImmunoRel™ (batch 20081217)]
24 Tocilizumab for the Treatment of Behcet's Syndrome Terminated NCT01693653 Phase 2 Tocilizumab
25 Phase II Randomized Trial With A Modified Dose & Schedule of Subcutaneously Administered Azacitidine & Erythropoietin v Azacitidine Alone in Patients With Low-Risk Myelodysplastic Syndromes (Less Than 11% Marrow & Peripheral Blood Blasts) Terminated NCT00379912 Phase 2 Azacitidine;Erythropoietin;Azacitidine (Monotherapy)
26 Treatment of Acute Deep Vein Thrombosis of the Lower Extremity With Intraclot, Pulse-Sprayed Recombinant Tissue Plasminogen Activator, Plus Heparin and Warfarin: A Pilot Study Completed NCT00001713 Phase 1 Recombinant Tissue Plasminogen Activator;Heparin;Warfarin
27 Prophylactic Antibiotics After Cesarean Recruiting NCT03187106 Phase 1 Cephalexin;Placebo;Metronidazole
28 Phase I Trial of Intravenous Fenretinide (4-HPR) Plus Intravenous Safingol for Patients With Relapsed Malignancies Recruiting NCT01553071 Phase 1 Fenretinide (4-HPR) plus Intravenous Safingol
29 Prospective Observational Study on Picclines' Complications at Brest Hospital Unknown status NCT03017911
30 Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices; Multicenter Study Unknown status NCT02256046
31 Treatment of Chorioamnionitis After Delivery Unknown status NCT00814905 saline;ampicillin gentamicin;Ampicillin gentamicin clindamycin;ampicillin gentamicin clindamycin
32 Effectiveness of Physical Exercise With Flow Restriction on the Diameter and the Flow of the Blood Vessels of the Forearm in Chronic Kidney Disease: a Randomized Clinical Trial Unknown status NCT02619968
33 Superficial Thrombophlebitis and Venous Thromboembolism: A Large Prospective Epidemiological Study Completed NCT00818688
34 Evaluation of Clinical Characteristics of Endovenous Sclerotherapy of Varicose Veins Completed NCT00954980
35 Comparison Between Transradial and Transfemoral Routes of Coronary Angiography and Interventions Completed NCT02983721
36 Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression Stockings: A Randomized Pilot Study Completed NCT01793194
37 Trans-perineal Pumpkin Seeds Phonophoresis as an Adjunct Treatment for Chronic Non-bacterial Prostatitis Completed NCT03461263
38 Assessing Efficacy of Axillary Web Syndrome Treatment Completed NCT03284008
39 Effect of Transcutaneous Electrical Nerve Stimulation on Pain Intensity of Patients With Hip Arthroplasty: A Randomized Control Trial Completed NCT03534999
40 Endovenous Laser Ablation of the Great Saphenous Vein Comparing 1920-nm and 1470-nm Diode Laser Completed NCT02504684
41 The Effect of Intraoperative Sequential Compression Devices on Fibrinolysis in Plastic Surgery Outpatients: A Randomized Trial Completed NCT03821597
42 Evaluation of Peripheral Intravenous Catheter and Urinary Catheters Present on Admission to the "Maladies Infectieuses aiguës" Department. Recruiting NCT03329768
43 Characteristics, Complications and Perinatal Outcomes in Placenta Previa Women: a Prospective, Matched Case-control Study Recruiting NCT03774667
44 HARapan kiTa ECP (External Counter Pulsation) Study HARTEC Study Recruiting NCT03991871
45 Randomized Comparative Evaluation of Midline Catheters for Thrombophlebitis Recruiting NCT03725293
46 Novel Strategy to Encourage Early Removal of Central Venous Catheters Recruiting NCT04136561
47 Risk of Venous Thromboembolism in Patients Receiving First-Line Chemotherapy for Disseminated Germ Cell Tumours - a Multi-Site Retrospective Cohort Study as Part of the Global Germ-Cell Cancer Group (G3) Consortium Active, not recruiting NCT04122430
48 Comparison of Efficacy of Biofeedback, Electrical Stimulation and Therapeutic Exercise in Patients With Knee Osteoarthritis Not yet recruiting NCT04197284
49 Role of Intravascular Ultrasound(IVUS) in Management of Acute and Chronic Iliocaval Obstruction Not yet recruiting NCT04024215
50 Peritonsillar Abscess: Aspiration Versus Tonsillectomy a Chaud Not yet recruiting NCT03326661 Penicillin V + metronidazol (Penicillin allergy: Clindamycin alone)

Search NIH Clinical Center for Thrombophlebitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Dalteparin
Dalteparin Sodium
Enoxaparin
heparin
heparin calcium
heparin sodium
HEPARIN SODIUM (BEEF LUNG)
heparin sodium, bovine
heparin sodium, porcine
Tolazoline
Tolazoline Hydrochloride
Warfarin
Warfarin Sodium
WARFARIN SODIUM ISOPROPANOL COMPLEX

Cochrane evidence based reviews: thrombophlebitis

Genetic Tests for Thrombophlebitis

Genetic tests related to Thrombophlebitis:

# Genetic test Affiliating Genes
1 Thrombophlebitis 29

Anatomical Context for Thrombophlebitis

MalaCards organs/tissues related to Thrombophlebitis:

40
Breast, Lung, Liver, Heart, Skin, Kidney, Brain

Publications for Thrombophlebitis

Articles related to Thrombophlebitis:

(show top 50) (show all 5512)
# Title Authors PMID Year
1
Continuous infusion of intermediate-purity factor VIII in haemophilia A patients undergoing elective surgery. 54 61
10444285 1999
2
[Thrombophlebitis in a patient with acute Q fever and anticardiolipin antibodies]. 54 61
9139149 1997
3
Effect of recombinant erythropoietin therapy on autoimmunity in systemic lupus erythematosus. 54 61
8023821 1994
4
A case of liver abscesses and porto-enteric fistula caused by an ingested toothpick: A review of the distinctive clinical and imaging features. 61
31956387 2020
5
A Lemierre-like syndrome caused by Staphylococcus aureus: an emerging disease. 61
31749395 2020
6
Trends in knee arthroscopy utilization: a gap in knowledge translation. 61
31359100 2020
7
Abdominal computed tomography (CT) scan in the evaluation of refractory puerperal fever: impact on management. 61
29973085 2020
8
An Unusual Case of Modified Lemierre's Syndrome Caused by Staphylococcus aureus Cellulitis. 61
32008035 2020
9
The role of anticoagulation in pylephlebitis: a retrospective examination of characteristics and outcomes. 61
31493290 2020
10
Isolated Superficial Dorsal Penile Vein Thrombosis due to Scabies Infestation. 61
32036835 2020
11
Diagnosis of suspected recurrent ipsilateral deep vein thrombosis with magnetic resonance direct thrombus imaging. 61
32016390 2020
12
Guidelines for the treatment of skin and mucosal lesions in Behçet's disease: A secondary publication. 61
31907947 2020
13
Safety of simultaneous versus staged bilateral opening-wedge high tibial osteotomy with locked plate and immediate weight bearing. 61
31385014 2020
14
Pulmonary embolism caused by postpartum ovarian vein thrombophlebitis after vaginal delivery: Case report and brief review of the literature. 61
31930727 2020
15
Ultrasound- and fluoroscopy-guided foam sclerotherapy for lower extremity venous ulcers. 61
31917182 2020
16
Validation of ICD-10 codes shows intracranial venous thrombosis incidence to be higher than previously reported. 61
30563370 2020
17
Lemierre's syndrome: A re-emerging infection. 61
31768313 2020
18
Multifocal Thrombophlebitis and Orbital Cellulitis. 61
31932573 2020
19
[Cavernous sinus syndrome secondary to thrombophlebitis due to Streptococcus intermedius complicated with vasculitis of the internal carotid artery and brain abscesses]. 61
31845752 2020
20
An atypical presentation of leiomyosarcoma causing extremity compartment syndrome of the crural region in a Dutch Warmblood mare: a case report. 61
31940682 2020
21
[Retained placenta in mares - an analysis of 121 cases]. 61
31810084 2019
22
Comparative and Predictor Analysis of 30-day Readmission, Reoperation, and Morbidity in Patients Undergoing Multilevel ACDF Versus Single and Multilevel ACCF Using the ACS-NSQIP Dataset. 61
31348176 2019
23
Surgical resection for suppurative thrombophlebitis of the great saphenous vein after radiofrequency ablation. 61
31799481 2019
24
Pattern of pulmonary vasculitis and major vascular involvement in Hughes-Stovin syndrome (HSS): brief report of eight cases. 61
31853734 2019
25
Chorioamnionitis and Infectious Complications after Vaginal Delivery. 61
31238347 2019
26
Bilateral abducens nerve palsy due to septic thrombophlebitis. 61
31737802 2019
27
Association of Mondor's disease with oral contraceptive pills. 61
31843777 2019
28
Left ventricular pacing in patients with preexisting tricuspid valve disease. 61
31844475 2019
29
Safety and Feasibility of Phenylephrine Administration Through a Peripheral Intravenous Catheter in a Neurocritical Care Unit. 61
31757173 2019
30
Toxocara canis Larval Migration Causing Verminous Pneumonia in Fading Puppies From 2 Scottish Terrier Litters. 61
31122148 2019
31
Penile Mondor's disease: Clinical and sonographic images. 61
31788306 2019
32
Short term exposure to fine particulate matter and hospital admission risks and costs in the Medicare population: time stratified, case crossover study. 61
31776122 2019
33
The national maternal near miss surveillance in China: A facility-based surveillance system covered 30 provinces. 61
31689786 2019
34
Bariatric surgery in the elderly: outcomes analysis of patients over 70 using the ACS-NSQIP database. 61
31611184 2019
35
Guidelines for superficial venous thrombosis. 61
31807127 2019
36
Contemporary management of lower extremity venous aneurysms. 61
31495768 2019
37
Klippel-Trénaunay syndrome: a case report of a rare vascular disorder identified in a rural Canadian hospital. 61
31721594 2019
38
Extra-cardiac endovascular infections in the critically ill. 61
31745594 2019
39
Outpatient Parenteral Antibiotic Therapy (OPAT) with Peripherally Inserted Central Catheter in Patients with Periprosthetic Joint Infection. 61
31387123 2019
40
Risk factors for a difficult intravenous access: A multicentre study comparing nurses' beliefs to evidence. 61
31162862 2019
41
Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases. 61
31309484 2019
42
Foam Sclerotherapy: An Emerging, Minimally Invasive And Safe Modality Of Treatment For Varicose Veins. 61
31965766 2019
43
Pain is a Limiting Factor in Patients Suitable for Transilluminated Powered Phlebectomy. 61
31675304 2019
44
Case report of two pregnancies and deliveries by a woman with Buerger disease. 61
31368151 2019
45
Association of Treatment of Chorioamnionitis with Non-Beta Lactam Antibiotics and Postcesarean Infectious Morbidity. 61
31600797 2019
46
Lemierre's Syndrome: An Atypical Presentation. 61
31201970 2019
47
[Lemierre syndrome - a frequently overlooked infectious disease]. 61
31594022 2019
48
The Use of Older Versus Newer Data in the National Surgical Quality Improvement Program Database Influences the Results of Total Hip Arthroplasty Outcomes Studies. 61
31773075 2019
49
Retroperitoneal abscess with pylephlebitis caused by lumbar acupuncture: a case report. 61
31619222 2019
50
Unusual cause of septic pulmonary emboli: Infected iliac aneurysm with suppurative thrombophlebitis. 61
31320213 2019

Variations for Thrombophlebitis

Expression for Thrombophlebitis

Search GEO for disease gene expression data for Thrombophlebitis.

Pathways for Thrombophlebitis

Pathways related to Thrombophlebitis according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.73 SERPINC1 PROS1 PROC F8 F7 F5
2
Show member pathways
12.63 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 SELP
3
Show member pathways
12.19 SERPINE1 PLG PLAT MTHFR F7 F2
4
Show member pathways
12.17 VWF SERPINF2 SERPINE1 SERPINC1 PROS1 PROC
5
Show member pathways
12.08 TGFB1 SELP PROS1 PROC F2
6 11.93 VWF SERPINF2 SERPINE1 SERPINC1 PROS1 PROC
7
Show member pathways
11.79 PROS1 PROC F7 F2
8 11.66 VWF TGFB1 F3
9 11.49 SERPINE1 PLG PLAT
10 11.39 TGFB1 SELP CD40LG
11 11.36 TGFB1 PLG PLAT
12 11.33 SELP PLG PLAT
13 10.85 PROS1 PROC F7 F2
14 10.74 SERPINF2 SERPINE1 PLG PLAT

GO Terms for Thrombophlebitis

Cellular components related to Thrombophlebitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 10.18 VWF SERPINF2 SERPINE1 SERPINC1 PROS1 PLG
2 extracellular region GO:0005576 10.11 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 PROS1
3 collagen-containing extracellular matrix GO:0062023 10 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 PLG
4 cell surface GO:0009986 9.98 TGFB1 SERPINF2 PLG PLAT F3 CD40LG
5 endoplasmic reticulum lumen GO:0005788 9.91 SERPINC1 PROC F8 F7 F5 F2
6 blood microparticle GO:0072562 9.87 TGFB1 SERPINF2 SERPINC1 PROS1 PLG F2
7 Golgi lumen GO:0005796 9.8 TGFB1 PROS1 PROC F7 F2
8 platelet alpha granule lumen GO:0031093 9.61 VWF TGFB1 SERPINF2 SERPINE1 PROS1 PLG
9 extracellular space GO:0005615 9.58 TGFB1 SERPINF2 SERPINE1 SERPINC1 SELP PROS1
10 serine-type peptidase complex GO:1905286 9.46 F7 F3

Biological processes related to Thrombophlebitis according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.95 SERPINC1 PROC PLG F5 F2 ALB
2 ER to Golgi vesicle-mediated transport GO:0006888 9.93 PROS1 PROC F8 F7 F5 F2
3 leukocyte migration GO:0050900 9.9 TGFB1 SELP PROS1 F2
4 response to hypoxia GO:0001666 9.88 TGFB1 PLAT MTHFR F7
5 negative regulation of endopeptidase activity GO:0010951 9.88 SERPINF2 SERPINE1 SERPINC1 PROS1
6 hemostasis GO:0007599 9.85 VWF SERPINC1 PROS1 PROC PLG F8
7 platelet activation GO:0030168 9.84 VWF F8 F2 CD40LG
8 acute-phase response GO:0006953 9.8 SERPINF2 F8 F2 CRP
9 response to wounding GO:0009611 9.79 VWF TGFB1 F2
10 blood coagulation, intrinsic pathway GO:0007597 9.73 VWF F8 F2 APOH
11 fibrinolysis GO:0042730 9.73 SERPINF2 SERPINE1 PROS1 PLG PLAT F2
12 negative regulation of fibrinolysis GO:0051918 9.72 SERPINF2 SERPINE1 PLG F2 APOH
13 negative regulation of blood coagulation GO:0030195 9.71 SERPINE1 PROS1 PROC APOH
14 positive regulation of collagen biosynthetic process GO:0032967 9.7 TGFB1 SERPINF2 F2
15 blood coagulation GO:0007596 9.7 VWF SERPINC1 PROS1 PROC PLG PLAT
16 regulation of blood coagulation GO:0030193 9.69 SERPINC1 F2 APOH
17 positive regulation of blood coagulation GO:0030194 9.67 SERPINE1 F7 F2 APOH
18 positive regulation of positive chemotaxis GO:0050927 9.62 F7 F3
19 plasminogen activation GO:0031639 9.62 PLAT APOH
20 response to cholesterol GO:0070723 9.61 TGFB1 F7
21 negative regulation of plasminogen activation GO:0010757 9.59 SERPINF2 SERPINE1
22 trans-synaptic signaling by BDNF, modulating synaptic transmission GO:0099183 9.57 PLG PLAT
23 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.56 F7 F3
24 blood coagulation, extrinsic pathway GO:0007598 9.55 F7 F3
25 platelet degranulation GO:0002576 9.36 VWF TGFB1 SERPINF2 SERPINE1 SELP PROS1

Molecular functions related to Thrombophlebitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 10.21 VWF TGFB1 SERPINF2 SERPINE1 SERPINC1 SELP
2 calcium ion binding GO:0005509 9.88 SELP PROS1 PROC F7 F2 CRP
3 signaling receptor binding GO:0005102 9.72 SERPINE1 PLG PLAT F7 F2
4 heparin binding GO:0008201 9.67 SERPINC1 SELP F2 APOH
5 copper ion binding GO:0005507 9.61 F8 F5 ALB
6 serine-type peptidase activity GO:0008236 9.55 PROC PLG PLAT F7 F2
7 protease binding GO:0002020 9.35 VWF SERPINF2 SERPINE1 SERPINC1 F3
8 serine-type endopeptidase activity GO:0004252 9.1 PROC PLG PLAT F7 F3 F2

Sources for Thrombophlebitis

3 CDC
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
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30 HMDB
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32 ICD10
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61 PubMed
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68 SNOMED-CT via HPO
69 TGDB
70 Tocris
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72 UMLS via Orphanet
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