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MCID: THR024
MIFTS: 61

Thrombosis

Categories: Cardiovascular diseases, Blood diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Thrombosis

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MalaCards integrated aliases for Thrombosis:

Name: Thrombosis 12 29 55 3 73
Thrombosis of Blood Vessel 73

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Blood diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:0060903
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Summaries for Thrombosis

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Disease Ontology : 12 A vascular disease caused by the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.

MalaCards based summary : Thrombosis, also known as thrombosis of blood vessel, is related to lateral sinus thrombosis and sagittal sinus thrombosis. An important gene associated with Thrombosis is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Dalteparin and Heparin have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and testes, and related phenotypes are homeostasis/metabolism and cardiovascular system

CDC : 3 Many people who have or have had family members with hemophilia will ask that their baby boys get tested soon after birth.

Wikipedia : 76 Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis \"clotting”) is the formation of a blood clot inside... more...

Sources

Related Diseases for Thrombosis

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Diseases related to Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 994)
# Related Disease Score Top Affiliating Genes
1 lateral sinus thrombosis 34.4 F9 MTHFR
2 sagittal sinus thrombosis 34.1 F2 F3 F5 SERPINC1
3 carotid artery thrombosis 34.0 F3 PLAT SERPINE1
4 cerebral sinovenous thrombosis 33.5 APOH F2 F3 F5 PROS1
5 heparin-induced thrombocytopenia 33.3 F3 SERPINC1
6 portal vein thrombosis 33.2 APOH F2 F5 JAK2 MTHFR SERPINC1
7 intracranial thrombosis 33.2 APOH F3 F5 MTHFR SERPINC1 VWF
8 may-thurner syndrome 32.9 APOH F5
9 coronary thrombosis 32.8 F3 GP1BA PLAT SERPINC1 SERPINE1 VWF
10 post-thrombotic syndrome 32.6 F2 F5 SERPINC1 SERPINE1
11 budd-chiari syndrome 32.4 APOH F2 F3 F5 JAK2 MTHFR
12 factor vii deficiency 32.4 F2 F3 F9
13 homocysteinemia 32.4 F2 F5 MTHFR SERPINC1
14 thrombocytosis 32.3 F2 F3 JAK2 SERPINC1
15 shwartzman phenomenon 32.2 F3 SERPINE1 THBD
16 polycythemia vera 32.2 F5 JAK2 THBD
17 antithrombin iii deficiency 32.1 APOH F2 F5 MTHFR SERPINC1
18 plasminogen activator inhibitor-1 deficiency 32.1 PLAT SERPINE1
19 buerger disease 32.1 APOH F2 MTHFR SERPINE1
20 hepatic veno-occlusive disease 32.0 F3 PLAT SERPINC1 SERPINE1 THBD
21 varicose veins 31.8 F2 F5 MTHFR SERPINC1 VWF
22 protein s deficiency 31.5 APOH F2 F3 F5 MTHFR PROS1
23 dysfibrinogenemia 31.5 F13A1 F2 F5 PLAT SERPINC1 THBD
24 antiphospholipid syndrome 31.3 APOH F2 F3 F5 MTHFR PLAT
25 essential thrombocythemia 31.3 F2 F3 JAK2 SERPINE1 THBD VWF
26 protein c deficiency 31.0 F2 F5 F9 HRG MTHFR PROC
27 homocystinuria 30.9 F5 MTHFR SERPINC1
28 portal hypertension 30.7 F2 JAK2 VWF
29 splenic infarction 30.7 APOH F2
30 lemierre's syndrome 30.6 F3 MTHFR SERPINE1
31 carotid artery occlusion 30.6 APOH F5 THBD
32 patent foramen ovale 30.6 F2 F5 MTHFR SERPINC1
33 factor v deficiency 30.5 F2 F3 F5 F9 TFPI VWF
34 pulmonary embolism 30.4 APOH F2 F3 F5 F9 MTHFR
35 acquired hemophilia 30.3 F3 F5 F9
36 sticky platelet syndrome 30.3 F5 SERPINC1 SERPINE1
37 endocarditis 30.2 APOH F2 PLAT SERPINC1
38 mesenteric vascular occlusion 30.1 F2 MTHFR
39 cerebral palsy 30.1 F2 F5 MTHFR
40 neonatal stroke 30.1 MTHFR PROC SERPINE1
41 afibrinogenemia 30.1 F2 F3 F5 VWF
42 eisenmenger syndrome 30.1 PLAT THBD VWF
43 acute myocardial infarction 30.0 F3 PLAT SERPINC1 SERPINE1 VWF
44 afibrinogenemia, congenital 30.0 F2 F3 VWF
45 fournier gangrene 30.0 F2 F3 SERPINC1
46 giant hemangioma 30.0 F2 F3 SERPINC1
47 venous insufficiency 30.0 F2 PLAT SERPINE1 VWF
48 vasculitis 30.0 APOH THBD VWF
49 hemoglobin e disease 30.0 F2 F5
50 sneddon syndrome 30.0 APOH F2 F5 SERPINC1

Graphical network of the top 20 diseases related to Thrombosis:



Diseases related to Thrombosis
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Symptoms & Phenotypes for Thrombosis

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MGI Mouse Phenotypes related to Thrombosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.36 JAK2 F3 MTHFR PLAT F5 APOH
2 cardiovascular system MP:0005385 10.32 F3 PLAT F5 F13A1 F9 F2
3 hematopoietic system MP:0005397 10.28 JAK2 F3 CD55 F13A1 F9 F2
4 immune system MP:0005387 10.15 JAK2 F3 CD55 F9 F2 TFPI
5 embryo MP:0005380 10.11 F2 JAK2 F3 F5 F9 TFPI
6 mortality/aging MP:0010768 10.09 JAK2 F3 MTHFR F5 APOH F13A1
7 integument MP:0010771 10.02 JAK2 F3 MTHFR F5 F2 TFPI
8 liver/biliary system MP:0005370 9.86 JAK2 F5 F9 PROS1 SERPINC1 SERPINE1
9 nervous system MP:0003631 9.73 F2 F3 MTHFR F5 TFPI PROS1
10 respiratory system MP:0005388 9.17 F2 F3 F13A1 PLAT SERPINE1 PROC
Sources

Drugs & Therapeutics for Thrombosis

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Drugs for Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1011)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dalteparin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 9005-49-6
2
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 9005-49-6 772 46507594
3
Enoxaparin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 9005-49-6 772
4
Phenprocoumon Approved, Investigational Phase 4,Phase 3,Phase 2 435-97-2 9908 54680692
5
Bivalirudin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 128270-60-0 16129704
6
Tenecteplase Approved Phase 4,Phase 3,Phase 2,Phase 1 191588-94-0
7
Tirofiban Approved Phase 4,Phase 3,Phase 2,Not Applicable 144494-65-5 60947
8
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
9 Nadroparin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 9041-08-1
10
Warfarin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 81-81-2 6691 54678486
11
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 120202-66-6, 113665-84-2 60606
12
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 274693-27-5 9871419
13
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 55142-85-3 5472
14
Abciximab Approved Phase 4,Phase 3,Phase 2,Not Applicable 143653-53-6
15
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-78-2 2244
16
Phenobarbital Approved, Investigational Phase 4,Phase 3 50-06-6 4763
17
Thrombin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18
Rivaroxaban Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 366789-02-8
19
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1197-18-8 5526
20
Tranylcypromine Approved, Investigational Phase 4,Phase 3 155-09-9 441233
21
Alprostadil Approved, Investigational Phase 4,Phase 3,Phase 2 745-65-3 149351 5280723
22
Acenocoumarol Approved, Investigational Phase 4,Phase 3,Not Applicable 152-72-7 9052 54676537
23
Salicylic acid Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 69-72-7 338
24
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 73590-58-6 4594
25
Pantoprazole Approved Phase 4,Phase 3,Phase 1,Not Applicable 102625-70-7 4679
26
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 159351-69-6 6442177
27
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 22916-47-8 4189
28
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53123-88-9 5284616 6436030 46835353
29
Nicorandil Approved, Investigational Phase 4 65141-46-0 47528
30
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-28-2 5757
31 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 979-32-8
32
Norethindrone Approved Phase 4,Not Applicable 68-22-4 6230
33
Polyestradiol phosphate Approved Phase 4,Phase 3,Phase 2,Not Applicable 28014-46-2
34
Coal tar Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 8007-45-2
35
Chromium Approved Phase 4,Phase 2,Phase 3,Not Applicable 7440-47-3 27668
36
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 33069-62-4 36314
37 fluindione Approved, Investigational Phase 4,Phase 3,Not Applicable 957-56-2
38
Nitric Oxide Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 10102-43-9 145068 160954
39
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 55-56-1 9552079 2713
40
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 61825-94-3 5310940 9887054 43805 6857599
41
Pravastatin Approved Phase 4,Phase 2,Phase 1 81093-37-0 54687
42
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 188627-80-7 123610
43
Cilostazol Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 73963-72-1 2754
44
Menthol Approved Phase 4,Phase 3,Phase 1,Not Applicable 2216-51-5 16666
45
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 3 71-58-9
46 Certoparin Approved, Investigational Phase 4,Phase 3
47
Progesterone Approved, Vet_approved Phase 4,Phase 3 57-83-0 5994
48
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 216974-75-3
49
Ranibizumab Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 347396-82-1 459903
50
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-02-2 5743

Interventional clinical trials:

(show top 50) (show all 4925)
# Name Status NCT ID Phase Drugs
1 Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis Unknown status NCT00450645 Phase 4 low molecular weight heparin
2 Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis Unknown status NCT01252420 Phase 4 Enoxaparin
3 Left Atrial Thrombus Reduction - Effect of Dabigatran Versus Phenprocoumon Unknown status NCT02591225 Phase 4 Dabigatranetexilate;Phenprocoumon
4 Rosuvastatin for Preventing Deep Vein Thrombosis Unknown status NCT01021488 Phase 4 Rosuvastatin 20mg/d for 14days;enoxaparin only
5 Intracoronary Cocktail Injection Combined With Thrombus Aspiration in STEMI Patients Treated With Primary Angioplasty Unknown status NCT02592694 Phase 4 cocktail
6 Resolution of Left Atrial-Appendage Thrombus - Effects of Dabigatran in Patients With AF Unknown status NCT02256683 Phase 4 Dabigatran etexilate;Phenprocoumon
7 Safety and Efficacy Study of OmniWave Endovascular System to Treat Deep Vein Thrombosis Unknown status NCT00640731 Phase 4
8 The Effect of Anticoagulation After Endoscopic Therapy in Cirrhotic Patients With Portal Vein Thrombosis Unknown status NCT02398357 Phase 4 Nadroparin Calcium and Warfarin
9 Rapid P2Y12 Receptor Inhibition Attenuates Inflammatory Cell Infiltration in Thrombus Aspirated From the STEMI Patients Unknown status NCT02639143 Phase 4 ticagrelor;Clopidogrel
10 Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users Unknown status NCT01063426 Phase 4 High dose Atorvastatin+enoxaparin;Enoxaparin
11 Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Unknown status NCT01383785 Phase 4
12 Thrombus Aspiration in Patients With STEMI Unknown status NCT02606435 Phase 4
13 Thrombus Aspiration During Percutaneous Coronary Intervention in Acute Non-ST-elevation Myocardial Infarction Study Unknown status NCT01013038 Phase 4
14 Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study. Unknown status NCT01914055 Phase 4
15 Hepatic Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Complicated by Portal Vein Tumor Thrombosis Unknown status NCT01350206 Phase 4
16 Antiaggregation in Primary Prevention of Vascular Access for Hemodialysis Unknown status NCT02055131 Phase 4 aspirin
17 Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA Unknown status NCT01670474 Phase 4 rt-PA (2mg/2mL) actilysis;rt-PA
18 Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery Unknown status NCT00983112 Phase 4 Human Fibrinogen and human thrombin (Evicel);Sodium Chlorure (Physiological saline)
19 Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside) Unknown status NCT00963781 Phase 4 Reduced duration (6 months) DAPT
20 Low Molecular Weight Heparin in Prevention of Recurrent Arteriovenous Graft Thrombosis in Chronic Hemodialysis Patients. Unknown status NCT01970280 Phase 4 Enoxaparin
21 Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty Unknown status NCT02453802 Phase 4 Tranexamic Acid 5%,5ml/amp;Tranexamic Acid 5%,5ml/amp;rivaroxaban (10mg);0.9% Normal Saline;0.9% Normal Saline
22 Randomized Trial of Standard vs ClearWay-infused Abciximab and Thrombectomy for Myocardial Infarction Unknown status NCT01499407 Phase 4 Abciximab
23 Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction Unknown status NCT01156662 Phase 4
24 The Use of Prostaglandin E1 in Head and Neck Microsurgery Unknown status NCT00733434 Phase 4 Prostaglandin E1
25 Randomised Controlled Trial of Needle Free Access Devices in Preventing Hemodialysis Blood Stream Infection Unknown status NCT01082770 Phase 4
26 Anticoagulation in Stent Intervention Unknown status NCT01141153 Phase 4 Acetylsalicylic Acid + clopidogrel + acenocoumarol;Acetylsalicylic Acid + clopidogrel
27 DEDICA (Dose of HEparin During Coronary Angioplasty) Trial Unknown status NCT01694459 Phase 4 Low-dose heparin;Standard dose heparin
28 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4 omeprazole;Pantoprazole
29 Late Incomplete Stent Apposition Evaluation II: Comparison Between Polimer-based and No-polimer Stent System. IVUS Based Study Unknown status NCT01375855 Phase 4
30 Multivessel Stenting Versus Staged Revascularization With Zotarolimus-eluting Stent for STEMI Unknown status NCT01781715 Phase 4
31 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4 Nicorandil;normal saline
32 Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease Study Unknown status NCT02642419 Phase 4 Rivaroxaban and single antiplatelet drug (aspirin, clopidogrel or prasugrel);Rivaroxaban
33 Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy Unknown status NCT02264743 Phase 4 Femoston Conti;EVOREL® CONTI
34 Cost Effectiveness Analysis In Patients With Heart Valve Prosthesis Unknown status NCT02022527 Phase 4 Acetyl Salicylic Acid;Warfarin;Placebo (for Aspirin)
35 EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography Unknown status NCT01371279 Phase 4
36 Triple Therapy in Patients on Oral Anticoagulation After Drug Eluting Stent Implantation Unknown status NCT00776633 Phase 4 aspirin;clopidogrel;oral anticoagulation
37 Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients Unknown status NCT01198379 Phase 4 aspirin;Placebo
38 Intravascular ULTrasound Guided Versus Conventional Angiography Guided Strategy to Deploy Zotarolimus and Everolimus Eluting Third Generation Stents in the Long Coronary Artery Lesions: ULTRA-ZET Trial Unknown status NCT01979744 Phase 4
39 Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction Unknown status NCT00976092 Phase 4 Prasugrel;Bivalirudin;Clopidogrel;Heparin
40 Rivaroxaban in Patients With Atrial Fibrillation and Coronary Artery Disease Undergoing Percutaneous Coronary Intervention Unknown status NCT02334254 Phase 4 rivaroxaban and ticagrel therapy;triple antithrombotic regimen with warfarin, asipirin and clopidogrel
41 Twelve vs 24 Months of Dual Antiplatelet Therapy in Patients With Coronary Revascularization for In-stent Restenosis Unknown status NCT02402491 Phase 4 12 months of P2Y12 receptor antagonist;24 months of P2Y12 receptor antagonist;Aspirin
42 Local Thrombolytics Before Thrombectomy in STEMI Unknown status NCT01568931 Phase 4 Urokinase;Saline
43 Reversal of the Antithrombotic Action of New Oral Anticoagulants Unknown status NCT01478282 Phase 4 Rivaroxaban;Dabigatran
44 Paradigm Shift in the Treatment of Patients With ACS Unknown status NCT02041650 Phase 4 Ticagrelor
45 Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI Unknown status NCT02012140 Phase 4 ticagrelor
46 Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents Unknown status NCT01268371 Phase 4
47 Fixed-dose vs. Phenotype-based PrAsugrel Dose to MATCH Therapeutic Zone in Asians With Acute Coronary Syndrome Unknown status NCT01951001 Phase 4 Prasugrel
48 Safety and Effectiveness of the Coronary Momo Stent Unknown status NCT01535625 Phase 4
49 Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease Unknown status NCT01418794 Phase 4
50 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4

Search NIH Clinical Center for Thrombosis

Inferred drug relations via UMLS 73 / NDF-RT 51 :
Sources

Genetic Tests for Thrombosis

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Genetic tests related to Thrombosis:

# Genetic test Affiliating Genes
1 Thrombosis 29
Sources

Anatomical Context for Thrombosis

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MalaCards organs/tissues related to Thrombosis:

41
Liver, Heart, Testes, Kidney, Endothelial, Lung, Brain
Sources

Publications for Thrombosis

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Articles related to Thrombosis:

(show top 50) (show all 7323)
# Title Authors Year
1
Thrombosis of the spleno-mesentiric portal axis following laparoscopic sleeve gastrectomy: A rare case report. ( 29438854 )
2018
2
Spontaneous intracranial hypotension complicated by cerebral venous thrombosis. ( 29955241 )
2018
3
Thrombopoietin receptor agonists and risk of portal vein thrombosis in patients with liver disease and thrombocytopenia: A meta-analysis. ( 29958825 )
2018
4
Late diagnosis of homocystinuria in an adult after extensive cerebral venous thrombosis. ( 29175875 )
2018
5
Response by Liberman et al to Letter Regarding Article, "Misdiagnosis of Cerebral Vein Thrombosis in the Emergency Department". ( 29976577 )
2018
6
Regenerative nodular hyperplasia, portal vein thrombosis and primary myelofibrosis: An unusual triple association. ( 29368941 )
2018
7
Locked-in Syndrome and<sup>18</sup>F-fluorodeoxyglucose-positron Emission Tomography/Computed Tomography: Observations from a Case of Basilar Artery Thrombosis. ( 29430121 )
2018
8
Predicting Post-Thrombotic Syndrome with Ultrasonographic Follow-Up after Deep Vein Thrombosis: A Systematic Review and Meta-Analysis. ( 29972864 )
2018
9
Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T) as a Risk Factor for Arterial Thrombosis in Georgian Patients. ( 29439641 )
2018
10
rLj-RGD3, a novel recombinant toxin protein from Lampetra japonica, prevents coronary thrombosis-induced acute myocardial infarction by inhibiting platelet functions in rats. ( 29407168 )
2018
11
Anticoagulation for Portal Vein Thrombosis in Liver Cirrhosis: Not Only Recanalize the PortalA Vein. ( 29351835 )
2018
12
Design and rationale for the Japanese Registry of Rivaroxaban Effectiveness &amp;amp; Safety for the Prevention of Recurrence in Patients with Deep Vein Thrombosis and Pulmonary Embolism (J'xactly) study. ( 29934383 )
2018
13
Serial long term follow up of a medically managed aortic prosthetic valve thrombosis. ( 29452310 )
2018
14
Neonatal cerebral sinovenous thrombosis: the anticoagulation debate. ( 29675894 )
2018
15
Adalimumab-based treatment versus DMARDs for venous thrombosis in BehAset syndrome. A retrospective study of 70 patients with vascular involvement. ( 29676522 )
2018
16
A case of portal vein thrombosis caused by blunt abdominal trauma in a patient with low protein C activity. ( 29923164 )
2018
17
Thrombosis and compartment syndrome requiring fasciotomy: Complications of internal iliac artery balloon catheters for morbidly adherent placenta. ( 29902690 )
2018
18
Prevention of recurrent venous thrombosis and post-thrombotic syndrome. ( 29795059 )
2018
19
Beneficial effect of combined spironolactone and quinapril treatment on thrombosis and hemostasis in 2K1C hypertensive rats. ( 29980144 )
2018
20
Congenital Thrombophilia in Patients With Superior Mesenteric Venous Thrombosis or Portal Vein Thrombosis. ( 29747524 )
2018
21
Portal Vein Thrombosis: Imaging the Spectrum of Disease With an Emphasis on MRI Features. ( 29792748 )
2018
22
Sticky Platelet Syndrome: An Unrecognized Cause of Acute Thrombosis and Graft Loss. ( 29850310 )
2018
23
Effects of statins on thrombosis development in patients with systemic lupus erythematosus and antiphospholipid antibodies. ( 28659045 )
2018
24
Cancer-associated thrombosis in patients with implanted ports: a prospective multicenter French cohort study (ONCOCIP). ( 29980524 )
2018
25
Liver Atrophy and Regeneration in Non-Cirrhotic Portal Vein Thrombosis: Effect of Surgical Shunts. ( 29377486 )
2018
26
Otogenic lateral sinus thrombosis in children: proposal of an experience-based treatment flowchart. ( 29948264 )
2018
27
Aneurysm of the inferior vena cava with thrombosis. ( 29445486 )
2018
28
Letter by Zhao et al Regarding Article, &amp;quot;Misdiagnosis of Cerebral Vein Thrombosis in the Emergency Department&amp;quot;. ( 29976578 )
2018
29
Serious Coronary Thrombosis and Pulmonary Artery Thrombosis Revealing BehAset's Disease. ( 29900996 )
2018
30
Optical Coherence Tomography for Guiding Plaque Stabilization in a Patient With Myocardial Infarction and Massive Coronary Thrombosis. ( 29958180 )
2018
31
Heparin-induced thrombocytopenia and thrombosis during high dose melphalan and autologous stem cell transplantation. ( 29903887 )
2018
32
Conservative management of neonatal cerebral sinovenous thrombosis with coexisting thrombophilia. ( 29708897 )
2018
33
Can thrombophilia predict recurrent catheter-related deep vein thrombosis in children? ( 29724900 )
2018
34
May-Thurner Syndrome Presenting as Acute Unexplained Deep Venous Thrombosis. ( 29793013 )
2018
35
Superior sagittal sinus thrombosis in a case of Mixed Connective Tissue Disease. ( 29848537 )
2018
36
Bland or tumor pulmonary artery stump thrombosis? ( 29448832 )
2018
37
The use of nonselective beta blockers is a risk factor for portal vein thrombosis in cirrhotic patients. ( 29451181 )
2018
38
Direct oral anticoagulant use in patients with thrombophilia, antiphospholipid syndrome or venous thrombosis of unusual sites: A narrative review. ( 29402471 )
2018
39
Treatment of Budd-Chiari Syndrome Complicated by Inferior Vena Cava Thrombosis: Individualised or Non-reproducible Strategy? ( 29731248 )
2018
40
Clinical and neuroimaging characteristics of cerebral sinovenous thrombosis in neonates undergoing cardiac surgery. ( 29221746 )
2018
41
Portal vein thrombosis: What surgeons need to know. ( 29963409 )
2018
42
Randomized controlled trial of rivaroxaban versus warfarin in the management of acute non-neoplastic portal vein thrombosis. ( 29886103 )
2018
43
Thoracic outlet syndrome presenting with subclavian vein thrombosis. ( 29369936 )
2018
44
The Development of Acute Systemic Multiple Thrombosis after Achieving Remission during Systemic Glucocorticoid Therapy for Acquired Hemophilia A. ( 29526954 )
2018
45
Newer Oral Anticoagulants in the Treatment of Acute Portal Vein Thrombosis in Patients with and without Cirrhosis. ( 29973997 )
2018
46
Risk Factors for Deep Vein Thrombosis or Pulmonary Embolus Following Anterior Cruciate Ligament Reconstruction. ( 29977948 )
2018
47
Reversible bioprosthetic valve thrombosis from eosinophilia. ( 29437808 )
2018
48
Cerebral Venous Sinus Thrombosis with Cerebral Hemorrhage Presenting with Status Epilepticus in Early Pregnancy. ( 29739085 )
2018
49
Coexistent Ipsilateral Internal Carotid Artery Occlusion and Cerebral Venous Thrombosis in Hepatitis C. ( 29349091 )
2018
50
How to perform and manage low-dose and slow/ultra-slow tissue type plasminogen activator infusion regimens in patients with prosthetic valve thrombosis. ( 29974321 )
2018
Sources

Variations for Thrombosis

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Sources

Expression for Thrombosis

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Search GEO for disease gene expression data for Thrombosis.
Sources

Pathways for Thrombosis

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Pathways related to Thrombosis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 66
Show member pathways
 13.16 APOH F13A1 F2 F3 F5 F9
2
Collagen chain trimerization 66
Show member pathways
 12.68 F13A1 F2 F3 F5 F9 PROC
3
Folate Metabolism 1
Show member pathways
 12.11 F2 MTHFR PLAT SERPINE1
4
Cell surface interactions at the vascular wall 66
Show member pathways
 12.01 F2 PROC PROS1 THBD
5
Complement and coagulation cascades 1 37
11.94 CD55 F13A1 F2 F3 F5 F9
6
Gamma carboxylation, hypusine formation and arylsulfatase activation 66
Show member pathways
 11.77 F2 F9 PROC PROS1
7
AGE-RAGE signaling pathway in diabetic complications 37
11.7 F3 JAK2 SERPINE1 THBD
8
Integrin alphaIIb beta3 signaling 66
Show member pathways
 11.69 F2 GP1BA VWF
9
Formation of Fibrin Clot (Clotting Cascade) 66
Show member pathways
 11.67 F13A1 F2 F3 F5 F9 GP1BA
10
Warfarin Pathway, Pharmacodynamics 61
10.8 F2 F9 PROC PROS1
11
Dissolution of Fibrin Clot 66
10.66 HRG PLAT SERPINE1
12
Platelet Adhesion to exposed collagen 66
10.62 GP1BA VWF
13
GP1b-IX-V activation signalling 66
10.49 GP1BA VWF
Sources

GO Terms for Thrombosis

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Cellular components related to Thrombosis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.97 APOH F2 F3 F5 F9 PLAT
2 cell surface GO:0009986 9.86 APOH CD55 F3 GP1BA HRG PLAT
3 extracellular matrix GO:0031012 9.85 APOH F3 PLAT SERPINE1 VWF
4 endoplasmic reticulum lumen GO:0005788 9.85 F2 F5 F9 PROC SERPINA10 SERPINC1
5 blood microparticle GO:0072562 9.8 F13A1 F2 HRG PROS1 SERPINC1
6 Golgi lumen GO:0005796 9.73 F2 F9 PROC PROS1
7 extracellular region GO:0005576 9.53 APOH CD55 F13A1 F2 F3 F5
8 platelet alpha granule GO:0031091 9.49 F5 VWF
9 platelet alpha granule lumen GO:0031093 9.43 F13A1 F5 HRG PROS1 SERPINE1 VWF
10 plasma membrane GO:0005886 10.29 CD55 F2 F3 F5 F9 GP1BA
11 extracellular exosome GO:0070062 10.13 APOH CD55 F2 F3 F9 GP1BA

Biological processes related to Thrombosis according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 ER to Golgi vesicle-mediated transport GO:0006888 9.99 CD55 F2 F5 F9 PROC PROS1
2 platelet degranulation GO:0002576 9.98 APOH F13A1 F5 HRG PROS1 SERPINE1
3 cellular protein metabolic process GO:0044267 9.95 F2 F5 PROC SERPINA10 SERPINC1
4 negative regulation of endopeptidase activity GO:0010951 9.95 HRG PROS1 SERPINA10 SERPINC1 SERPINE1 TFPI
5 cytokine-mediated signaling pathway GO:0019221 9.91 F13A1 F3 GP1BA JAK2
6 leukocyte migration GO:0050900 9.88 F2 PROC PROS1 THBD
7 negative regulation of peptidase activity GO:0010466 9.87 SERPINA10 SERPINC1 SERPINE1 TFPI
8 platelet activation GO:0030168 9.86 F2 GP1BA HRG VWF
9 blood coagulation GO:0007596 9.86 F13A1 F2 F3 F5 F9 GP1BA
10 signal peptide processing GO:0006465 9.8 F2 F9 PROC PROS1
11 blood coagulation, intrinsic pathway GO:0007597 9.8 APOH F2 F9 GP1BA VWF
12 regulation of complement activation GO:0030449 9.78 CD55 F2 PROS1
13 regulation of blood coagulation GO:0030193 9.77 APOH F2 GP1BA HRG SERPINC1
14 peptidyl-glutamic acid carboxylation GO:0017187 9.76 F2 F9 PROC PROS1
15 fibrinolysis GO:0042730 9.73 F2 GP1BA HRG PLAT PROS1 SERPINE1
16 negative regulation of fibrinolysis GO:0051918 9.72 APOH F2 HRG SERPINE1 THBD
17 positive regulation of blood coagulation GO:0030194 9.71 APOH F2 SERPINE1
18 blood coagulation, extrinsic pathway GO:0007598 9.7 F3 F9 TFPI
19 negative regulation of blood coagulation GO:0030195 9.63 APOH PROC PROS1 SERPINE1 TFPI THBD
20 plasminogen activation GO:0031639 9.6 APOH PLAT
21 negative regulation of platelet activation GO:0010544 9.59 F2 THBD
22 negative regulation of cell adhesion mediated by integrin GO:0033629 9.58 HRG SERPINE1
23 hemostasis GO:0007599 9.47 F13A1 F2 F3 F5 F9 GP1BA

Molecular functions related to Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.85 F2 HRG JAK2 PLAT SERPINE1
2 serine-type peptidase activity GO:0008236 9.73 F2 F9 PLAT PROC
3 serine-type endopeptidase activity GO:0004252 9.65 F2 F3 F9 PLAT PROC
4 peptidase inhibitor activity GO:0030414 9.62 SERPINA10 SERPINC1 SERPINE1 TFPI
5 endopeptidase inhibitor activity GO:0004866 9.58 HRG PROS1 TFPI
6 protease binding GO:0002020 9.46 F3 SERPINC1 SERPINE1 VWF
7 immunoglobulin binding GO:0019865 9.37 HRG VWF
8 heparin binding GO:0008201 9.35 APOH F2 HRG SERPINA10 SERPINC1
9 serine-type endopeptidase inhibitor activity GO:0004867 9.02 HRG SERPINA10 SERPINC1 SERPINE1 TFPI
Sources

Sources for Thrombosis

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3 CDC
4