MCID: THN005
MIFTS: 19

Thunderclap Headache

Categories: Rare diseases

Aliases & Classifications for Thunderclap Headache

MalaCards integrated aliases for Thunderclap Headache:

Name: Thunderclap Headache 53
Benign Thunderclap Headache 53

Classifications:



Summaries for Thunderclap Headache

MalaCards based summary : Thunderclap Headache, also known as benign thunderclap headache, is related to reversible cerebral vasoconstriction syndrome and headache. The drugs Antibodies and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include pituitary, brain and heart.

Wikipedia : 75 A thunderclap headache is a headache that is severe and sudden-onset. It is defined as a severe headache... more...

Related Diseases for Thunderclap Headache

Diseases related to Thunderclap Headache via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 reversible cerebral vasoconstriction syndrome 11.8
2 headache 11.2
3 pituitary apoplexy 10.6
4 intracranial hypotension 10.6
5 spontaneous intracranial hypotension 10.6
6 migraine with or without aura 1 10.6
7 cerebral aneurysms 10.5
8 aneurysm 10.5
9 thrombophilia due to thrombin defect 10.5
10 stroke, ischemic 10.5
11 cerebrovascular disease 10.5
12 vasculitis 10.5
13 encephalopathy 10.5
14 intracranial aneurysm 10.4
15 pheochromocytoma 10.4
16 adrenal gland pheochromocytoma 10.4
17 thrombosis 10.4
18 myocardial infarction 10.3
19 exertional headache 10.3
20 ataxia and polyneuropathy, adult-onset 10.2
21 central nervous system vasculitis 10.2
22 hypertensive encephalopathy 10.2
23 intracranial hypertension 10.2
24 cough headache 10.2
25 new daily-persistent headache 10.2
26 depression 10.2
27 systemic lupus erythematosus 10.1
28 otitis media 10.1
29 trigeminal neuralgia 10.1
30 hydrocephalus due to congenital stenosis of aqueduct of sylvius 10.1
31 ocular motor apraxia 10.1
32 kearns-sayre syndrome 10.1
33 branchiootic syndrome 1 10.1
34 headache associated with sexual activity 10.1
35 angina pectoris 10.1
36 paraganglioma 10.1
37 ptosis 10.1
38 pre-eclampsia 10.1
39 multiple personality disorder 10.1
40 hemiplegia 10.1
41 arteriovenous malformation 10.1
42 suppurative otitis media 10.1
43 visual epilepsy 10.1
44 vogt-koyanagi-harada disease 10.1
45 migraine without aura 10.1
46 intracranial vasospasm 10.1
47 hellp syndrome 10.1
48 chronic purulent otitis media 10.1
49 personality disorder 10.1
50 oligodendroglioma 10.1

Graphical network of the top 20 diseases related to Thunderclap Headache:



Diseases related to Thunderclap Headache

Symptoms & Phenotypes for Thunderclap Headache

Drugs & Therapeutics for Thunderclap Headache

Drugs for Thunderclap Headache (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies
2 Immunologic Factors
3 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Reversible Cerebral Vasoconstriction Syndrome With Concomitant Transient Global Amnesia : a Serie of 3 Cases Report Completed NCT03739008
2 Telephone Triage and Spontaneous Subarachnoid Haemorrhage; Predictors of Timely Admission to Neurosurgical Care Completed NCT03786068
3 Association Between Reversible Cerebral Vasoconstriction Syndrome and Herpes Zoster Infection Recruiting NCT03509701

Search NIH Clinical Center for Thunderclap Headache

Genetic Tests for Thunderclap Headache

Anatomical Context for Thunderclap Headache

MalaCards organs/tissues related to Thunderclap Headache:

41
Pituitary, Brain, Heart, Testes, Breast, Placenta

Publications for Thunderclap Headache

Articles related to Thunderclap Headache:

(show top 50) (show all 375)
# Title Authors PMID Year
1
The clinical spectrum of reversible cerebral vasoconstriction syndrome: The Italian Project on Stroke at Young Age (IPSYS). 38
31060368 2019
2
Fatal reversible cerebral vasoconstriction syndrome: A systematic review of case series and case reports. 38
31416730 2019
3
Presentation and Management of Headache in Pituitary Apoplexy. 38
31359174 2019
4
A systemic lupus erythematosus patient with thunderclap headache: reversible cerebral vasoconstriction syndrome. 38
31042127 2019
5
The Thunderclap Headache: Approach and Management in the Emergency Department. 38
30879843 2019
6
Leading symptoms in cerebrovascular diseases: what about headache? 38
30891639 2019
7
"Worst Headache of Life" in a Migraineur: Marginal Value of Emergency Department CT Scanning. 38
30661996 2019
8
An RCVS Spectrum Disorder? New Daily Persistent Headache Starting as a Single Thunderclap Headache (3 New Cases). 38
30830966 2019
9
Decompression Hemicraniectomy for Refractory Intracranial Hypertension in Reversible Cerebral Vasoconstriction Syndrome. 38
31001036 2019
10
Thunderclap Headache and Cerebral Vasoconstriction Secondary to Pheochromocytoma. 38
30801609 2019
11
Reversible Cerebral Vasoconstriction Syndrome Associated with Coronary Artery Vasospasm. 38
31236082 2019
12
A Case of Reversible Cerebral Vasoconstriction Syndrome Triggered by High-Dose Methotrexate in a Boy With Lymphoma. 38
30985924 2019
13
[Reversible cerebral vasoconstriction syndrome associated with anastrozole: an unusual cause of high impact]. 38
30855709 2019
14
Reversible Cerebral Vasoconstriction Syndrome Due to Midodrine in a Patient with Autonomic Dysreflexia. 38
31172001 2019
15
RCVS2 score and diagnostic approach for reversible cerebral vasoconstriction syndrome. 38
30635475 2019
16
Orgasmic migraine aura: Report of two cases. 38
29682978 2019
17
Upshaw-Schulman syndrome diagnosed during pregnancy complicated by reversible cerebral vasoconstriction syndrome. 38
30471945 2018
18
Thunderclap headache: an update. 38
30334463 2018
19
[Reversible Cerebral Vasoconstriction Syndrome Without Typical Thunderclap Headache Complicated by Intracranial Hemorrhage and Posterior Reversible Encephalopathy Syndrome:A Case Report]. 38
30572309 2018
20
Management of anesthesia for cesarean delivery in a patient with an unruptured intracranial aneurysm. 38
30057147 2018
21
Severe Reversible Cerebral Vasoconstriction Syndrome with Large Posterior Cerebral Infarction. 38
30087075 2018
22
Convexity Subarachnoid Hemorrhage Secondary to Adalidumab in a Patient with Ulcerative Colitis. 38
30746014 2018
23
Fatal Intracranial Hemorrhage Associated with Oral Warfarin Use. 38
30656075 2018
24
Primary angiitis of the CNS and reversible cerebral vasoconstriction syndrome: A comparative study. 38
30232250 2018
25
Clinical significance of centripetal propagation of vasoconstriction in patients with reversible cerebral vasoconstriction syndrome: A retrospective case-control study. 38
29495882 2018
26
Triptan-induced Reversible Cerebral Vasoconstriction Syndrome Presenting With Thunderclap Headache and Paraparesis. 38
30169369 2018
27
Serial testing of the ICHD-3 beta diagnostic criteria for probable reversible cerebral vasoconstriction syndrome: A prospective validation study. 38
29160084 2018
28
Bath-Related Headache. 38
30073574 2018
29
The Patient with Thunderclap Headache. 38
30007749 2018
30
Clinical Reasoning: A 41-year-old man with thunderclap headache. 38
29967209 2018
31
Cerebral Infarction and Cortical Subarachnoid Hemorrhage Preceded Vascular Contraction in Reversible Cerebral Vasoconstriction Syndrome Patient with Hidden Breast Cancer. 38
30258266 2018
32
Headache in transient ischemic attacks. 38
30054753 2018
33
Unruptured aneurysm producing thunderclap headache treated with endovascular coil embolization. 38
30028482 2018
34
An exceptional presentation of pituicytoma apoplexy: A case report. 38
29928451 2018
35
Delayed Establishment of Collateral Circulation from Posterior Meningeal Artery After Proximal Occlusion of Posterior Inferior Cerebellar Artery: Case Report and Literature Review. 38
29751186 2018
36
Vertebral artery dissection stroke in evolution presented with postural headache as initial manifestation. 38
30069291 2018
37
Reversible cerebral vasoconstriction syndrome: an important and common cause of thunderclap and recurrent headaches. 38
29274685 2018
38
Cough Headache Presenting with Reversible Cerebral Vasoconstriction Syndrome. 38
29321411 2018
39
Anticipation in a family with primary familial brain calcification caused by an SLC20A2 variant. 38
29680161 2018
40
Isoflavones and gastrointestinal infection: Two potential triggers for reversible cerebral vasoconstriction syndrome. 38
28610434 2018
41
Characteristics and demographics of reversible cerebral vasoconstriction syndrome: A large prospective series of Korean patients. 38
28592180 2018
42
Dihydroergotamine Complicating Reversible Cerebral Vasoconstriction Syndrome in Status Migrainosus. 38
29725183 2018
43
An unusual cause of thunderclap headache after eating the hottest pepper in the world - "The Carolina Reaper". 38
29632122 2018
44
Bilateral Infarction of the Recurrent Arteries of Heubner Following Clipping of an Anterior Communicating Artery Aneurysm. 38
30370237 2018
45
Reversible cerebral vasoconstriction syndrome. 38
27915588 2018
46
[Migraine 'masks': differential diagnosis of acute headache]. 38
29460913 2018
47
To Head CT Scan or Not: The Clinical Quandary in Suspected Subarachnoid Hemorrhage; a Validation Study on Ottawa Subarachnoid Hemorrhage Rule. 38
31172091 2018
48
Pituitary apoplexy - A single center retrospective study from the neurosurgical perspective and review of the literature. 38
29055223 2017
49
Postpartum Headache: A Prospective Study. 38
29073663 2017
50
Pneumocephalus Presenting as Sudden Thunderclap Headache. 38
29114285 2017

Variations for Thunderclap Headache

Expression for Thunderclap Headache

Search GEO for disease gene expression data for Thunderclap Headache.

Pathways for Thunderclap Headache

GO Terms for Thunderclap Headache

Sources for Thunderclap Headache

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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