MCID: THN005
MIFTS: 19

Thunderclap Headache

Categories: Rare diseases

Aliases & Classifications for Thunderclap Headache

MalaCards integrated aliases for Thunderclap Headache:

Name: Thunderclap Headache 52
Benign Thunderclap Headache 52

Classifications:



Summaries for Thunderclap Headache

MalaCards based summary : Thunderclap Headache, also known as benign thunderclap headache, is related to reversible cerebral vasoconstriction syndrome and headache. The drugs Antibodies and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include pituitary, brain and heart.

Wikipedia : 74 A thunderclap headache is a headache that is severe and has a sudden onset. It is defined as a severe... more...

Related Diseases for Thunderclap Headache

Diseases related to Thunderclap Headache via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 reversible cerebral vasoconstriction syndrome 11.8
2 headache 11.2
3 pituitary apoplexy 10.6
4 intracranial hypotension 10.6
5 spontaneous intracranial hypotension 10.6
6 cerebral aneurysms 10.5
7 aneurysm 10.5
8 migraine with or without aura 1 10.5
9 thrombophilia due to thrombin defect 10.5
10 stroke, ischemic 10.5
11 vasculitis 10.5
12 encephalopathy 10.5
13 intracranial aneurysm 10.4
14 pheochromocytoma 10.4
15 adrenal gland pheochromocytoma 10.4
16 myocardial infarction 10.3
17 thrombosis 10.3
18 exertional headache 10.3
19 ataxia and polyneuropathy, adult-onset 10.2
20 central nervous system vasculitis 10.2
21 hypertensive encephalopathy 10.2
22 intracranial hypertension 10.2
23 cough headache 10.2
24 new daily-persistent headache 10.2
25 depression 10.2
26 systemic lupus erythematosus 10.1
27 marfan syndrome 10.1
28 otitis media 10.1
29 trigeminal neuralgia 10.1
30 hydrocephalus due to congenital stenosis of aqueduct of sylvius 10.1
31 ocular motor apraxia 10.1
32 kearns-sayre syndrome 10.1
33 branchiootic syndrome 1 10.1
34 headache associated with sexual activity 10.1
35 angina pectoris 10.1
36 paraganglioma 10.1
37 ptosis 10.1
38 aortic dissection 10.1
39 pre-eclampsia 10.1
40 multiple personality disorder 10.1
41 hemiplegia 10.1
42 arteriovenous malformation 10.1
43 suppurative otitis media 10.1
44 visual epilepsy 10.1
45 vogt-koyanagi-harada disease 10.1
46 migraine without aura 10.1
47 intracranial vasospasm 10.1
48 hellp syndrome 10.1
49 chronic purulent otitis media 10.1
50 personality disorder 10.1

Graphical network of the top 20 diseases related to Thunderclap Headache:



Diseases related to Thunderclap Headache

Symptoms & Phenotypes for Thunderclap Headache

Drugs & Therapeutics for Thunderclap Headache

Drugs for Thunderclap Headache (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies
2 Immunologic Factors
3 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Reversible Cerebral Vasoconstriction Syndrome With Concomitant Transient Global Amnesia : a Serie of 3 Cases Report Completed NCT03739008
2 Telephone Triage and Spontaneous Subarachnoid Haemorrhage; Predictors of Timely Admission to Neurosurgical Care Completed NCT03786068
3 Identification of Reversible Cerebral Vasoconstriction Syndrome's Precipitating Factors. Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome Recruiting NCT04179383
4 Association Between Reversible Cerebral Vasoconstriction Syndrome and Herpes Zoster Infection Recruiting NCT03509701

Search NIH Clinical Center for Thunderclap Headache

Genetic Tests for Thunderclap Headache

Anatomical Context for Thunderclap Headache

MalaCards organs/tissues related to Thunderclap Headache:

40
Pituitary, Brain, Heart, Breast, Placenta, Testes

Publications for Thunderclap Headache

Articles related to Thunderclap Headache:

(show top 50) (show all 392)
# Title Authors PMID Year
1
Vertebral Artery Dissection. 61
32476584 2020
2
Other primary headaches-thunderclap-, cough-, exertional-, and sexual headache. 61
32130497 2020
3
An uncommon case of thunderclap headache in a patient with Marfan syndrome. 61
32367353 2020
4
[Drug-induced reversible cerebral vasoconstriction syndrome : Ustekinumab as possible trigger?] 61
32435940 2020
5
[Reversible cerebral vasoconstriction syndrome causing acute-onset headache]. 61
32515327 2020
6
Pneumocephalus and Chemical Meningitis after Inadvertent Dural Puncture during Lumbar Epidural Injection. 61
32395453 2020
7
Reversible Cerebral Vasoconstriction Syndrome Triggered by Typhoon Hagibis in 2019: Report of 2 Cases. 61
32100287 2020
8
The burden of headache following aneurysmal subarachnoid hemorrhage: a prospective single-center cross-sectional analysis. 61
32016589 2020
9
[Reversible cerebral vasoconstriction syndrome - a common cause of thunderclap headache]. 61
32009625 2020
10
Long-Term Outcomes After Reversible Cerebral Vasoconstriction Syndrome. 61
31842705 2020
11
Concomitant reversible cerebral vasoconstriction syndrome and transient global amnesia. 61
31650256 2020
12
Reversible cerebral vasoconstriction syndrome concomitant with cerebral venous sinus thrombosis following ovarian tumor resection: A report of two cases. 61
32547815 2020
13
Fatal reversible cerebral vasoconstriction syndrome: A systematic review of case series and case reports. 61
31416730 2019
14
Reversible cerebral vasoconstriction with thunderclap headache: A case report. 61
31804357 2019
15
The Spectrum of Nontraumatic Convexity Subarachnoid Hemorrhage. 61
31677961 2019
16
Acute Headache in the Emergency Setting. 61
31589569 2019
17
[Reversible Cerebral Vasoconstriction Syndrome with Cortical Subarachnoid Hemorrhage due to Acute Cortical Infarction Beneath the Sulcus:A Case Report]. 61
31666424 2019
18
The clinical spectrum of reversible cerebral vasoconstriction syndrome: The Italian Project on Stroke at Young Age (IPSYS). 61
31060368 2019
19
Presentation and Management of Headache in Pituitary Apoplexy. 61
31359174 2019
20
The Thunderclap Headache: Approach and Management in the Emergency Department. 61
30879843 2019
21
A systemic lupus erythematosus patient with thunderclap headache: reversible cerebral vasoconstriction syndrome. 61
31042127 2019
22
"Worst Headache of Life" in a Migraineur: Marginal Value of Emergency Department CT Scanning. 61
30661996 2019
23
Leading symptoms in cerebrovascular diseases: what about headache? 61
30891639 2019
24
An RCVS Spectrum Disorder? New Daily Persistent Headache Starting as a Single Thunderclap Headache (3 New Cases). 61
30830966 2019
25
Thunderclap Headache and Cerebral Vasoconstriction Secondary to Pheochromocytoma. 61
30801609 2019
26
Decompression Hemicraniectomy for Refractory Intracranial Hypertension in Reversible Cerebral Vasoconstriction Syndrome. 61
31001036 2019
27
Reversible Cerebral Vasoconstriction Syndrome Associated with Coronary Artery Vasospasm. 61
31236082 2019
28
A Case of Reversible Cerebral Vasoconstriction Syndrome Triggered by High-Dose Methotrexate in a Boy With Lymphoma. 61
30985924 2019
29
[Reversible cerebral vasoconstriction syndrome associated with anastrozole: an unusual cause of high impact]. 61
30855709 2019
30
Reversible Cerebral Vasoconstriction Syndrome Due to Midodrine in a Patient with Autonomic Dysreflexia. 61
31172001 2019
31
RCVS2 score and diagnostic approach for reversible cerebral vasoconstriction syndrome. 61
30635475 2019
32
Orgasmic migraine aura: Report of two cases. 61
29682978 2019
33
Upshaw-Schulman syndrome diagnosed during pregnancy complicated by reversible cerebral vasoconstriction syndrome. 61
30471945 2018
34
Thunderclap headache: an update. 61
30334463 2018
35
[Reversible Cerebral Vasoconstriction Syndrome Without Typical Thunderclap Headache Complicated by Intracranial Hemorrhage and Posterior Reversible Encephalopathy Syndrome:A Case Report]. 61
30572309 2018
36
Severe Reversible Cerebral Vasoconstriction Syndrome with Large Posterior Cerebral Infarction. 61
30087075 2018
37
Management of anesthesia for cesarean delivery in a patient with an unruptured intracranial aneurysm. 61
30057147 2018
38
Convexity Subarachnoid Hemorrhage Secondary to Adalidumab in a Patient with Ulcerative Colitis. 61
30746014 2018
39
Fatal Intracranial Hemorrhage Associated with Oral Warfarin Use. 61
30656075 2018
40
Primary angiitis of the CNS and reversible cerebral vasoconstriction syndrome: A comparative study. 61
30232250 2018
41
Clinical significance of centripetal propagation of vasoconstriction in patients with reversible cerebral vasoconstriction syndrome: A retrospective case-control study. 61
29495882 2018
42
Triptan-induced Reversible Cerebral Vasoconstriction Syndrome Presenting With Thunderclap Headache and Paraparesis. 61
30169369 2018
43
Serial testing of the ICHD-3 beta diagnostic criteria for probable reversible cerebral vasoconstriction syndrome: A prospective validation study. 61
29160084 2018
44
Bath-Related Headache. 61
30073574 2018
45
The Patient with Thunderclap Headache. 61
30007749 2018
46
Cerebral Infarction and Cortical Subarachnoid Hemorrhage Preceded Vascular Contraction in Reversible Cerebral Vasoconstriction Syndrome Patient with Hidden Breast Cancer. 61
30258266 2018
47
Headache in transient ischemic attacks. 61
30054753 2018
48
Delayed Establishment of Collateral Circulation from Posterior Meningeal Artery After Proximal Occlusion of Posterior Inferior Cerebellar Artery: Case Report and Literature Review. 61
29751186 2018
49
An exceptional presentation of pituicytoma apoplexy: A case report. 61
29928451 2018
50
Unruptured aneurysm producing thunderclap headache treated with endovascular coil embolization. 61
30028482 2018

Variations for Thunderclap Headache

Expression for Thunderclap Headache

Search GEO for disease gene expression data for Thunderclap Headache.

Pathways for Thunderclap Headache

GO Terms for Thunderclap Headache

Sources for Thunderclap Headache

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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