MCID: THY024
MIFTS: 28

Thymus Adenocarcinoma

Categories: Cancer diseases, Immune diseases, Endocrine diseases

Aliases & Classifications for Thymus Adenocarcinoma

MalaCards integrated aliases for Thymus Adenocarcinoma:

Name: Thymus Adenocarcinoma 12 15
Adenocarcinoma of the Thymus 12
Thymic Adenocarcinoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4923
NCIt 50 C6459
UMLS 73 C1336743

Summaries for Thymus Adenocarcinoma

Disease Ontology : 12 A thymic carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Thymus Adenocarcinoma, also known as adenocarcinoma of the thymus, is related to tubular adenocarcinoma and mucinous adenocarcinoma. An important gene associated with Thymus Adenocarcinoma is CDX2 (Caudal Type Homeobox 2), and among its related pathways/superpathways are FOXA1 transcription factor network and Surfactant metabolism. Affiliated tissues include thymus.

Related Diseases for Thymus Adenocarcinoma

Diseases related to Thymus Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 151)
# Related Disease Score Top Affiliating Genes
1 tubular adenocarcinoma 30.7 CDX2 KRT20
2 mucinous adenocarcinoma 30.3 CDX2 KRT20 KRT7
3 papillary adenocarcinoma 29.7 CEACAM5 KRT7
4 villous adenoma 10.7 CDX2 KRT20
5 acute interstitial pneumonia 10.7 SFTPA1 SFTPA2
6 splenic artery aneurysm 10.6 SFTPA1 SFTPA2
7 anal paget's disease 10.6 CDX2 CEACAM5
8 ovary neuroendocrine neoplasm 10.6 CDX2 KRT7
9 seminal vesicle adenocarcinoma 10.5 KRT20 KRT7
10 transverse colon cancer 10.5 KRT20 KRT7
11 ovarian large-cell neuroendocrine carcinoma 10.5 KRT20 KRT7
12 eyelid neoplasm 10.5 KRT20 KRT7
13 large intestine adenocarcinoma 10.5 KRT20 KRT7
14 linitis plastica 10.5 KRT20 KRT7
15 poland syndrome 10.5 SFTPA1 SFTPA2
16 epithelial predominant wilms' tumor 10.5 CDX2 KRT7
17 lung acinar adenocarcinoma 10.5 KRT20 KRT7
18 small cell carcinoma of the bladder 10.5 KRT20 KRT7
19 gastric signet ring cell adenocarcinoma 10.5 CDX2 CEACAM5
20 adenoid squamous cell carcinoma 10.5 KRT20 KRT7
21 eccrine sweat gland neoplasm 10.5 KRT20 KRT7
22 bronchiolo-alveolar adenocarcinoma 10.5 CDX2 KRT7
23 nasal cavity adenocarcinoma 10.5 CDX2 KRT7
24 anal canal adenocarcinoma 10.5 CDX2 KRT7
25 intratubular embryonal carcinoma 10.5 KRT20 KRT7
26 lung sarcoma 10.5 SFTPA1 SFTPA2
27 medulloepithelioma 10.5 KRT20 KRT7
28 glycogen-rich clear cell breast carcinoma 10.5 KRT20 KRT7
29 renal pelvis carcinoma 10.5 KRT20 KRT7
30 paget disease, extramammary 10.5 KRT20 KRT7
31 microinvasive gastric cancer 10.5 CDX2 CEACAM5
32 superior mesenteric artery syndrome 10.4 CDX2 CEACAM5
33 mucinous cystadenocarcinoma 10.4 KRT20 KRT7
34 lymphoepithelioma-like carcinoma 10.4 KRT20 KRT7
35 biliary tract neoplasm 10.4 CDX2 KRT7
36 duodenum cancer 10.4 CDX2 KRT7
37 cystadenofibroma 10.4 KRT20 KRT7
38 basal cell carcinoma, infundibulocystic 10.4 KRT20 PTGER4
39 hidradenocarcinoma 10.4 CDX2 KRT7
40 inverted papilloma 10.4 KRT20 KRT7
41 ovarian cystic teratoma 10.4 KRT20 KRT7
42 anus cancer 10.4 CDX2 KRT7
43 gastric tubular adenocarcinoma 10.4 CDX2 KRT7
44 large cell neuroendocrine carcinoma 10.4 KRT20 KRT7
45 mammary paget's disease 10.4 KRT20 KRT7
46 ovarian benign neoplasm 10.3 KRT7 NAPSA
47 papillary adenoma 10.3 KRT7 NAPSA
48 benign mesothelioma 10.3 KRT20 KRT7
49 papillary thymic adenocarcinoma 10.3 CD5 PTGER4
50 necrotizing sialometaplasia 10.3 CD5 KRT7

Graphical network of the top 20 diseases related to Thymus Adenocarcinoma:



Diseases related to Thymus Adenocarcinoma

Symptoms & Phenotypes for Thymus Adenocarcinoma

Drugs & Therapeutics for Thymus Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Thymus Adenocarcinoma

Genetic Tests for Thymus Adenocarcinoma

Anatomical Context for Thymus Adenocarcinoma

MalaCards organs/tissues related to Thymus Adenocarcinoma:

41
Thymus

Publications for Thymus Adenocarcinoma

Articles related to Thymus Adenocarcinoma:

# Title Authors Year
1
Primary Mucinous Adenocarcinoma of the Thymus: A Case Report and Literature Review. ( 28956749 )
2017
2
A Rare Case of Primary Tubular Adenocarcinoma of the Thymus, Enteric Immunophenotype: A Case Study and Review of the Literature. ( 26040775 )
2015
3
Adenocarcinoma of the thymus, enteric type: report of 2 cases, and proposal for a novel subtype of thymic carcinoma. ( 25517960 )
2015
4
Papillary adenocarcinoma of the thymus: case report and review of the literature. ( 18611939 )
2010
5
Mucinous adenocarcinoma of the thymus: a distinct variant of thymic carcinoma. ( 18722686 )
2009
6
Mucinous adenocarcinoma of the thymus: a case report. ( 18670316 )
2008
7
Primary mucinous adenocarcinoma of the thymus: a case report and review of the literature. ( 16454563 )
2006
8
Tubular adenocarcinoma of the thymus: case report and review of the literature. ( 16959713 )
2006
9
Adenocarcinoma of the thymus: mucinous subtype. ( 15754301 )
2005

Variations for Thymus Adenocarcinoma

Expression for Thymus Adenocarcinoma

Search GEO for disease gene expression data for Thymus Adenocarcinoma.

Pathways for Thymus Adenocarcinoma

GO Terms for Thymus Adenocarcinoma

Cellular components related to Thymus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 clathrin-coated endocytic vesicle GO:0045334 9.16 SFTPA1 SFTPA2
2 multivesicular body GO:0005771 8.96 SFTPA1 SFTPA2
3 lamellar body GO:0042599 8.62 SFTPA1 SFTPA2

Biological processes related to Thymus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 toll-like receptor signaling pathway GO:0002224 9.37 SFTPA1 SFTPA2
2 developmental process GO:0032502 9.32 SFTPA1 SFTPA2
3 respiratory gaseous exchange GO:0007585 9.26 SFTPA1 SFTPA2
4 positive regulation of phagocytosis GO:0050766 9.16 SFTPA1 SFTPA2
5 cellular protein metabolic process GO:0044267 9.13 NAPSA SFTPA1 SFTPA2
6 surfactant homeostasis GO:0043129 8.8 NAPSA SFTPA1 SFTPA2

Molecular functions related to Thymus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 8.96 SFTPA1 SFTPA2
2 monosaccharide binding GO:0048029 8.62 SFTPA1 SFTPA2

Sources for Thymus Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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