MCID: THY024
MIFTS: 28

Thymus Adenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Immune diseases

Aliases & Classifications for Thymus Adenocarcinoma

MalaCards integrated aliases for Thymus Adenocarcinoma:

Name: Thymus Adenocarcinoma 12 15
Adenocarcinoma of the Thymus 12
Thymic Adenocarcinoma 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4923
NCIt 51 C6459
UMLS 74 C1336743

Summaries for Thymus Adenocarcinoma

Disease Ontology : 12 A thymic carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Thymus Adenocarcinoma, also known as adenocarcinoma of the thymus, is related to mucinous adenocarcinoma and tubular adenocarcinoma. An important gene associated with Thymus Adenocarcinoma is CDX2 (Caudal Type Homeobox 2), and among its related pathways/superpathways are FOXA1 transcription factor network and Surfactant metabolism. Affiliated tissues include thymus.

Related Diseases for Thymus Adenocarcinoma

Diseases related to Thymus Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)
# Related Disease Score Top Affiliating Genes
1 mucinous adenocarcinoma 30.5 CDX2 KRT20 KRT7
2 tubular adenocarcinoma 30.4 CDX2 KRT20
3 appendix adenocarcinoma 29.9 CDX2 KRT20 KRT7
4 papillary adenocarcinoma 29.8 CEACAM5 KRT7
5 adenocarcinoma 10.4
6 vaginal benign neoplasm 10.4 CDX2 KRT20
7 vaginal adenoma 10.4 CDX2 KRT20
8 vaginal tubulovillous adenoma 10.4 CDX2 KRT20
9 villous adenoma 10.4 CDX2 KRT20
10 lung sarcoma 10.3 SFTPA1 SFTPA2
11 acute interstitial pneumonia 10.3 SFTPA1 SFTPA2
12 splenic artery aneurysm 10.3 SFTPA1 SFTPA2
13 cystadenoma 10.3 KRT20 KRT7
14 anal paget's disease 10.3 CDX2 CEACAM5
15 ovary neuroendocrine neoplasm 10.3 CDX2 KRT7
16 seminal vesicle adenocarcinoma 10.3 KRT20 KRT7
17 transverse colon cancer 10.3 KRT20 KRT7
18 papillary transitional carcinoma 10.2 KRT20 KRT7
19 eyelid carcinoma 10.2 KRT20 KRT7
20 large intestine adenocarcinoma 10.2 KRT20 KRT7
21 duodenum adenocarcinoma 10.2 CDX2 KRT7
22 linitis plastica 10.2 KRT20 KRT7
23 lung acinar adenocarcinoma 10.2 KRT20 KRT7
24 small cell carcinoma 10.2 KRT20 KRT7
25 epithelial predominant wilms' tumor 10.2 CDX2 KRT7
26 small cell carcinoma of the bladder 10.2 KRT20 KRT7
27 fibroepithelial basal cell carcinoma 10.2 CEACAM5 KRT20
28 nasal cavity cancer 10.2 CDX2 KRT7
29 adenoid squamous cell carcinoma 10.2 KRT20 KRT7
30 intratubular embryonal carcinoma 10.2 KRT20 KRT7
31 nasal cavity adenocarcinoma 10.2 CDX2 KRT7
32 anal canal adenocarcinoma 10.2 CDX2 KRT7
33 bile duct adenoma 10.2 KRT20 KRT7
34 gastric signet ring cell adenocarcinoma 10.2 CDX2 CEACAM5
35 medulloepithelioma 10.2 KRT20 KRT7
36 glycogen-rich clear cell breast carcinoma 10.2 KRT20 KRT7
37 renal pelvis carcinoma 10.2 KRT20 KRT7
38 paget disease, extramammary 10.2 KRT20 KRT7
39 lymphoepithelioma-like carcinoma 10.2 KRT20 KRT7
40 duodenum cancer 10.2 CDX2 KRT7
41 cystadenofibroma 10.2 KRT20 KRT7
42 mucinous cystadenocarcinoma 10.2 KRT20 KRT7
43 anus cancer 10.2 CDX2 KRT7
44 basal cell carcinoma, infundibulocystic 10.2 KRT20 PTGER4
45 ovarian cystic teratoma 10.2 KRT20 KRT7
46 hidradenocarcinoma 10.2 CDX2 KRT7
47 gastric tubular adenocarcinoma 10.2 CDX2 KRT7
48 large cell neuroendocrine carcinoma 10.2 KRT20 KRT7
49 mammary paget's disease 10.2 KRT20 KRT7
50 fetal adenoma 10.2 CD5 CEACAM5

Graphical network of the top 20 diseases related to Thymus Adenocarcinoma:



Diseases related to Thymus Adenocarcinoma

Symptoms & Phenotypes for Thymus Adenocarcinoma

Drugs & Therapeutics for Thymus Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Thymus Adenocarcinoma

Genetic Tests for Thymus Adenocarcinoma

Anatomical Context for Thymus Adenocarcinoma

MalaCards organs/tissues related to Thymus Adenocarcinoma:

42
Thymus

Publications for Thymus Adenocarcinoma

Articles related to Thymus Adenocarcinoma:

(show all 12)
# Title Authors Year
1
Mucinous adenocarcinoma of the thymus: report of a case. ( 28474330 )
2018
2
Primary Mucinous Adenocarcinoma of the Thymus: A Case Report and Literature Review. ( 28956749 )
2017
3
Mucinous cystic tumor with CK20 and CDX2 expression of the thymus: Is this a benign counterpart of adenocarcinoma of the thymus, enteric type? ( 26581569 )
2016
4
A Rare Case of Primary Tubular Adenocarcinoma of the Thymus, Enteric Immunophenotype: A Case Study and Review of the Literature. ( 26040775 )
2015
5
Adenocarcinoma of the thymus, enteric type: report of 2 cases, and proposal for a novel subtype of thymic carcinoma. ( 25517960 )
2015
6
Primary adenocarcinoma of the thymus: an immunohistochemical and molecular study with review of the literature. ( 23725376 )
2013
7
Papillary adenocarcinoma of the thymus: case report and review of the literature. ( 18611939 )
2010
8
Mucinous adenocarcinoma of the thymus: a distinct variant of thymic carcinoma. ( 18722686 )
2009
9
Mucinous adenocarcinoma of the thymus: a case report. ( 18670316 )
2008
10
Primary mucinous adenocarcinoma of the thymus: a case report and review of the literature. ( 16454563 )
2006
11
Tubular adenocarcinoma of the thymus: case report and review of the literature. ( 16959713 )
2006
12
Adenocarcinoma of the thymus: report of two cases, including a previously undescribed mucinous subtype. ( 12502935 )
2003

Variations for Thymus Adenocarcinoma

Expression for Thymus Adenocarcinoma

Search GEO for disease gene expression data for Thymus Adenocarcinoma.

Pathways for Thymus Adenocarcinoma

GO Terms for Thymus Adenocarcinoma

Cellular components related to Thymus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 multivesicular body GO:0005771 9.16 SFTPA1 SFTPA2
2 clathrin-coated endocytic vesicle GO:0045334 8.96 SFTPA1 SFTPA2
3 lamellar body GO:0042599 8.62 SFTPA1 SFTPA2

Biological processes related to Thymus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of phagocytosis GO:0050766 9.32 SFTPA1 SFTPA2
2 toll-like receptor signaling pathway GO:0002224 9.26 SFTPA1 SFTPA2
3 respiratory gaseous exchange GO:0007585 9.16 SFTPA1 SFTPA2
4 cellular protein metabolic process GO:0044267 9.13 NAPSA SFTPA1 SFTPA2
5 surfactant homeostasis GO:0043129 8.8 NAPSA SFTPA1 SFTPA2

Molecular functions related to Thymus Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 8.96 SFTPA1 SFTPA2
2 monosaccharide binding GO:0048029 8.62 SFTPA1 SFTPA2

Sources for Thymus Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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