MCID: THY007
MIFTS: 37

Thymus Lipoma

Categories: Cancer diseases, Endocrine diseases, Immune diseases

Aliases & Classifications for Thymus Lipoma

MalaCards integrated aliases for Thymus Lipoma:

Name: Thymus Lipoma 12 15
Thymolipoma 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1975
NCIt 51 C6452
UMLS 74 C1336744

Summaries for Thymus Lipoma

Disease Ontology : 12 An immune system organ benign neoplasm that is located in the thymus and derives from fat cells.

MalaCards based summary : Thymus Lipoma, also known as thymolipoma, is related to predominantly cortical thymoma and myasthenia gravis. An important gene associated with Thymus Lipoma is MB (Myoglobin), and among its related pathways/superpathways are Cytoskeletal Signaling and Keratinization. Affiliated tissues include thymus, kidney and colon.

Related Diseases for Thymus Lipoma

Diseases related to Thymus Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 164)
# Related Disease Score Top Affiliating Genes
1 predominantly cortical thymoma 30.0 KRT19 PTPRC
2 myasthenia gravis 10.5
3 myasthenia gravis congenital 10.5
4 metal allergy 10.5 CD4 CD8A
5 polyclonal hypergammaglobulinemia 10.4 CD4 CD8A
6 mesenchymoma 10.4 HMGA2 MB
7 myofibroma 10.4 CD1A MB
8 endolymphatic sac tumor 10.4 KRT7 KRT8
9 bile duct adenoma 10.4 KRT20 KRT7
10 cystic basal cell carcinoma 10.4 KRT20 KRT7
11 seminal vesicle adenocarcinoma 10.4 KRT20 KRT7
12 transverse colon cancer 10.4 KRT20 KRT7
13 appendix adenocarcinoma 10.4 KRT20 KRT7
14 malignant syringoma 10.4 KRT20 KRT7
15 glandular cystitis 10.4 KRT20 KRT7
16 papillary transitional carcinoma 10.4 KRT20 KRT7
17 eyelid carcinoma 10.4 KRT20 KRT7
18 krukenberg carcinoma 10.4 KRT20 KRT7
19 orbital cancer 10.4 MB SYP
20 large intestine adenocarcinoma 10.4 KRT20 KRT7
21 hidrocystoma 10.4 KRT7 KRT8
22 ovarian large-cell neuroendocrine carcinoma 10.4 KRT20 SYP
23 cervical adenoma malignum 10.4 HMGA2 KRT7
24 linitis plastica 10.4 KRT20 KRT7
25 lung acinar adenocarcinoma 10.4 KRT20 KRT7
26 apocrine sweat gland neoplasm 10.4 KRT7 KRT8
27 rhabdoid cancer 10.4 MB SYP
28 cutaneous ganglioneuroma 10.4 KRT20 SYP
29 vulval paget's disease 10.4 KRT20 KRT7
30 cervical mucinous adenocarcinoma 10.4 HMGA2 KRT7
31 bile duct cystadenocarcinoma 10.4 KRT20 KRT7
32 nasal cavity cancer 10.3 KRT7 KRT8
33 kidney rhabdoid cancer 10.3 MB PTPRC
34 jejunal adenocarcinoma 10.3 KRT20 KRT7
35 nodular tenosynovitis 10.3 HMGA2 PTPRC
36 ovarian mucinous adenocarcinoma 10.3 KRT20 KRT7
37 appendix disease 10.3 KRT20 KRT7
38 ovary neuroendocrine neoplasm 10.3 KRT7 SYP
39 gastric diffuse adenocarcinoma 10.3 KRT20 KRT7
40 ectopic thymus 10.3 CD5 SYP
41 meibomian cyst 10.3 KRT20 KRT7
42 thymoma, familial 10.3
43 thymoma 10.3
44 papillary serous adenocarcinoma 10.3 KRT20 KRT7
45 mucinous adenofibroma 10.3 KRT7 SYP
46 bladder adenocarcinoma 10.3 KRT20 KRT7
47 chronic cystitis 10.3 KRT20 KRT7
48 vulva adenocarcinoma 10.3 KRT20 KRT7
49 brooke-spiegler syndrome 10.3 KRT7 KRT8
50 mixed type thymoma 10.3 CD5 SYP

Graphical network of the top 20 diseases related to Thymus Lipoma:



Diseases related to Thymus Lipoma

Symptoms & Phenotypes for Thymus Lipoma

Drugs & Therapeutics for Thymus Lipoma

Search Clinical Trials , NIH Clinical Center for Thymus Lipoma

Genetic Tests for Thymus Lipoma

Anatomical Context for Thymus Lipoma

MalaCards organs/tissues related to Thymus Lipoma:

42
Thymus, Kidney, Colon, Appendix, Skin, Ovary, Thyroid

The Foundational Model of Anatomy Ontology organs/tissues related to Thymus Lipoma:

20
The Thymus

Publications for Thymus Lipoma

Articles related to Thymus Lipoma:

(show top 50) (show all 115)
# Title Authors Year
1
Consecutive cases of thyrolipomatosis and thymolipoma: a case report. ( 29044875 )
2019
2
Thoracoscopic resection for mediastinal thymolipoma in a child. ( 29963757 )
2019
3
Giant thymolipoma of mediastinum and neck - initially misdiagnosed as liposarcoma by core needle biopsy. ( 30598961 )
2018
4
Pure Red Cell Aplasia Associated with Thymolipoma: Complete Anaemia Resolution following Thymectomy. ( 30402302 )
2018
5
The added value of chemical shift MRI in the preoperative diagnosis of thymolipoma. ( 29714656 )
2018
6
Huge thymolipoma compressing the heart in a 20-year-old patient. ( 26207001 )
2017
7
Giant thymolipoma: A rare case presentation. ( 26265159 )
2017
8
Progressive Dyspnea in a 40-Year-Old Man Caused by Giant Mediastinal Thymolipoma. ( 27293949 )
2016
9
Aortopulmonary ectopic parathyroid gland and concurrent thymolipoma. ( 27634826 )
2016
10
B3 thymoma arising within thymolipoma. ( 26517631 )
2015
11
Giant thymolipoma in a young child initially diagnosed as cardiomegaly. ( 26508197 )
2015
12
Giant mediastinal thymolipoma in a patient with Gardner's syndrome. ( 26557924 )
2015
13
Thymoma type B1 arising in a giant supradiaphragmatic thymolipoma. ( 24887884 )
2014
14
Thymolipoma in child: a case diagnosed by correlation of ultrasound-guided fine needle aspiration (EUS-FNA) cytology and computed tomography with histological confirmation. ( 23902624 )
2014
15
Giant thymolipoma in an infant. ( 24621238 )
2014
16
Paediatric giant cervicomediastinal thymolipoma. ( 24849642 )
2014
17
Giant thymolipoma: case report of an unusual mediastinal tumor. ( 24985048 )
2014
18
Thymolipoma with sebaceous differentiation: a hitherto unreported variant of thymolipoma. ( 23358435 )
2013
19
An incidental unique mediastinal mass in an asymptomatic young patient: thymolipoma. ( 23581273 )
2013
20
Mediastinal thymolipoma with striated myoid cells: report of a peculiar case. ( 24421857 )
2013
21
Thymoma originating in a giant thymolipoma: a rare intrathoracic lesion. ( 23992709 )
2013
22
Large thymolipoma causing primarily respiratory distress. ( 22919867 )
2012
23
Huge thymolipoma. ( 20713373 )
2011
24
Giant thymoliposarcoma presented like thymolipoma. ( 21345689 )
2011
25
Giant mediastinal mass: thymolipoma. ( 21606717 )
2011
26
Massive thymolipoma in a young asymptomatic male. ( 21871321 )
2011
27
Huge mediastinal mass with minimal symptoms: thymolipoma. ( 22699472 )
2011
28
Giant mediastinal thymolipoma in 35-year-old women. ( 24250956 )
2011
29
Thymolipoma. A report of nine cases, with emphasis on its association with myasthenia gravis. ( 20107952 )
2010
30
Thymolipoma, report of a case suggesting an origin from thymic true hyperplasia. ( 19233859 )
2010
31
A typical thymic carcinoid tumour within a thymolipoma: report of a case and review of combined tumours of the thymus. ( 22791779 )
2010
32
Giant thymolipoma causing cardiocompressive syndrome with chronic heart failure. ( 19161808 )
2009
33
Thymolipoma: clues to pathogenesis revealed by cytogenetics. ( 19433298 )
2009
34
Giant thymolipoma causing cardiopulmonary compression. ( 19447043 )
2009
35
Images in cardiothoracic surgery. Giant thymolipoma involving both chest cavities. ( 19463642 )
2009
36
Giant mediastinal thymolipoma simulating cardiomegaly. ( 19782275 )
2009
37
Asymptomatic giant mediastinal mass: a rare case of thymolipoma. ( 19918636 )
2009
38
Thymoma and thymic carcinoma arising in a thymolipoma: report of a unique case. ( 18480395 )
2009
39
Respiratory failure caused by giant thymolipoma. ( 18640359 )
2008
40
Clinical and histopathological features of a thymolipoma in a dog. ( 18460628 )
2008
41
Thoracoscopic resection of a giant thymolipoma in a 4-year-old girl. ( 18922057 )
2008
42
Thymolipoma combined with hyperthyroidism discovered by neurological symptoms. ( 17505419 )
2007
43
Thymolipoma associated with myasthenia gravis. ( 17444169 )
2007
44
Mediastinal thymolipoma: a rare occurrence with striated myoid cells. ( 17557569 )
2007
45
Mediastinal thymolipoma: an analysis of 10 cases. ( 17986126 )
2007
46
A rare combination of thymic tumor: radiologically invisible thymolipoma associated with myasthenia gravis. ( 16936410 )
2006
47
Giant thymolipoma in association with a high production of carbohydrate antigen 19-9 and an increased acetylcholine antibody titer. ( 16733187 )
2006
48
Thymolipoma of the anterior mediastinum: videothoracoscopic removal using a bilateral approach. ( 16967386 )
2006
49
Thymolipoma in a cat. ( 15771949 )
2005
50
Giant thymolipoma. ( 15972442 )
2005

Variations for Thymus Lipoma

Expression for Thymus Lipoma

Search GEO for disease gene expression data for Thymus Lipoma.

Pathways for Thymus Lipoma

GO Terms for Thymus Lipoma

Cellular components related to Thymus Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.93 CD1A CD1C CD4 CD5 CD8A PTPRC
2 external side of plasma membrane GO:0009897 9.62 CD4 CD5 CD8A PTPRC
3 apicolateral plasma membrane GO:0016327 9.43 KRT19 KRT8
4 costamere GO:0043034 9.4 KRT19 KRT8
5 dystrophin-associated glycoprotein complex GO:0016010 9.37 KRT19 KRT8
6 cell surface GO:0009986 9.33 CD1B CD4 PTPRC
7 T cell receptor complex GO:0042101 9.26 CD4 CD8A
8 cell periphery GO:0071944 9.13 KRT19 KRT8 PTPRC
9 intermediate filament GO:0005882 8.92 KRT19 KRT20 KRT7 KRT8

Biological processes related to Thymus Lipoma according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.91 CD1A CD1B CD1C CD4 CD8A
2 immune response GO:0006955 9.88 CD1A CD1B CD1C CD4 CD8A
3 adaptive immune response GO:0002250 9.83 CD1A CD1B CD1C CD4
4 regulation of immune response GO:0050776 9.76 CD1A CD1B CD1C CD8A
5 keratinization GO:0031424 9.67 KRT19 KRT20 KRT7 KRT8
6 cornification GO:0070268 9.56 KRT19 KRT20 KRT7 KRT8
7 response to vitamin D GO:0033280 9.55 CD4 PTH
8 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.54 CD4 PTPRC
9 T cell activation GO:0042110 9.5 CD4 CD8A PTPRC
10 positive regulation of stem cell proliferation GO:2000648 9.49 HMGA2 PTPRC
11 positive regulation of cell proliferation in bone marrow GO:0071864 9.43 HMGA2 PTH
12 cell differentiation involved in embryonic placenta development GO:0060706 9.4 KRT19 KRT8
13 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 9.33 CD1A CD1B CD1C
14 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 9.13 CD1A CD1B CD1C
15 positive regulation of T cell mediated cytotoxicity GO:0001916 8.92 CD1A CD1B CD1C PTPRC

Molecular functions related to Thymus Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopeptide binding GO:0071723 9.33 CD1A CD1B CD1C
2 endogenous lipid antigen binding GO:0030883 9.13 CD1A CD1B CD1C
3 exogenous lipid antigen binding GO:0030884 8.8 CD1A CD1B CD1C

Sources for Thymus Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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