Thymus Sarcomatoid Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Thymus Sarcomatoid Carcinoma

MalaCards integrated aliases for Thymus Sarcomatoid Carcinoma:

Name: Thymus Sarcomatoid Carcinoma ¹² ¹⁵

Thymic Sarcomatoid Carcinoma ⁷¹

Thymic Carcinosarcoma ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:8138

NCIt ⁴⁹ C6463

UMLS ⁷¹ C1335924

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Summaries for Thymus Sarcomatoid Carcinoma

MalaCards based summary : Thymus Sarcomatoid Carcinoma, also known as thymic sarcomatoid carcinoma, is related to carcinosarcoma and spindle cell carcinoma, and has symptoms including fatigue, fever and chest pain. An important gene associated with Thymus Sarcomatoid Carcinoma is PITPNM1 (Phosphatidylinositol Transfer Protein Membrane Associated 1), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include thymus and skeletal muscle, and related phenotype is normal.

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Related Diseases for Thymus Sarcomatoid Carcinoma

Diseases related to Thymus Sarcomatoid Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)

#	Related Disease	Score	Top Affiliating Genes
1	carcinosarcoma	10.2
2	spindle cell carcinoma	10.0
3	sclerosing hepatic carcinoma	10.0	CD5 AFP
4	pineal region teratoma	10.0	SYP AFP
5	rectum neuroendocrine neoplasm	10.0	SYP AFP
6	ovarian germ cell teratoma	10.0	SYP AFP
7	endometrial small cell carcinoma	10.0	SYP AFP
8	pancreatic acinar cell adenocarcinoma	10.0	SYP AFP
9	tracheal lymphoma	10.0	SYP CD5
10	pineal gland cancer	10.0	SYP AFP
11	thymoma, familial	10.0
12	thymoma	10.0
13	spindle cell thymoma	10.0
14	ovarian germ cell cancer	10.0	SYP AFP
15	malignant teratoma	9.9	SYP AFP
16	pancreatoblastoma	9.9	SYP AFP
17	pancreatic endocrine carcinoma	9.9	SYP AFP
18	obstructive hydrocephalus	9.9	SYP AFP
19	mature teratoma	9.9	SYP AFP
20	pineoblastoma	9.9	SYP AFP
21	sertoli-leydig cell tumor	9.9	SYP AFP
22	leydig cell tumor	9.9	SYP AFP
23	sertoli cell tumor	9.9	SYP AFP
24	mixed cell type cancer	9.9	SYP AFP
25	acinar cell carcinoma	9.9	SYP AFP
26	cystic teratoma	9.9	SYP AFP
27	fibrolamellar carcinoma	9.9	SYP AFP
28	tubular adenocarcinoma	9.9	SYP AFP
29	benign teratoma	9.9	SYP AFP
30	thymus gland disease	9.9	SYP CD5
31	thymic carcinoma	9.9	SYP CD5
32	cavernous hemangioma	9.8	SYP AFP
33	cystadenoma	9.8	SYP AFP
34	cardiovascular organ benign neoplasm	9.8	SYP AFP
35	hepatic tuberculosis	9.8	ALB AFP
36	hepatic infarction	9.8	ALB AFP
37	hepatic coma	9.8	ALB AFP
38	hepatoid adenocarcinoma	9.8	ALB AFP
39	klatskin's tumor	9.8	ALB AFP
40	esophageal varix	9.8	ALB AFP
41	hepatorenal syndrome	9.8	ALB AFP
42	endodermal sinus tumor	9.8	ALB AFP
43	autoimmune disease of blood	9.8	CD5 ALB
44	c syndrome	9.8	ALB AFP
45	splenic disease	9.7	CD5 ALB
46	hepatic vascular disease	9.7	ALB AFP
47	plasma cell neoplasm	9.7	CD5 ALB
48	cranial nerve palsy	9.7	SYP ALB
49	metal metabolism disorder	9.7	ALB AFP
50	cecal disease	9.7	SYP ALB

Graphical network of the top 20 diseases related to Thymus Sarcomatoid Carcinoma:

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Symptoms & Phenotypes for Thymus Sarcomatoid Carcinoma

UMLS symptoms related to Thymus Sarcomatoid Carcinoma:

fatigue, fever, chest pain, coughing

MGI Mouse Phenotypes related to Thymus Sarcomatoid Carcinoma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	normal	MP:0002873	9.02	ALB CD5 FOLR2 NKX6-2 SYP

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Drugs & Therapeutics for Thymus Sarcomatoid Carcinoma

Search Clinical Trials , NIH Clinical Center for Thymus Sarcomatoid Carcinoma

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Genetic Tests for Thymus Sarcomatoid Carcinoma

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Anatomical Context for Thymus Sarcomatoid Carcinoma

MalaCards organs/tissues related to Thymus Sarcomatoid Carcinoma:

⁴⁰

Thymus, Skeletal Muscle

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Publications for Thymus Sarcomatoid Carcinoma

Articles related to Thymus Sarcomatoid Carcinoma:

#	Title	Authors	PMID	Year
1	Complete Resection of Thymic Sarcomatoid Carcinoma Through Total Aortic Arch Replacement. ⁶¹	Oka S...Tanaka F	27847081	2016
2	Four cases of invasive anterior mediastinal tumors definitively diagnosed by the chamberlain procedure. ⁶¹	Shimizu J...Minato H	23574996	2014
3	[Thymic sarcomatoid carcinoma; report of a case]. ⁶¹	Sano I...Taniguchi H	23917062	2013
4	Multiple inflammatory cytokine-productive ThyL-6 cell line established from a patient with thymic carcinoma. ⁶¹	Inai K...Noriki S	18691242	2008
5	Thymic sarcomatoid carcinoma with skeletal muscle differentiation: report of two cases, one with cytogenetic analysis. ⁶¹	Eimoto T...Wang HJ	11903597	2002

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Genes for Thymus Sarcomatoid Carcinoma

Genes related to Thymus Sarcomatoid Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PITPNM1	Phosphatidylinositol Transfer Protein Membrane Associated 1	Protein Coding	6	DISEASES inferred ¹⁵
2	AMIGO1	Adhesion Molecule With Ig Like Domain 1	Protein Coding	5.63	DISEASES inferred ¹⁵
3	FOLR2	Folate Receptor Beta	Protein Coding	5.55	DISEASES inferred ¹⁵
4	NKX6-2	NK6 Homeobox 2	Protein Coding	5.02	DISEASES inferred ¹⁵
5	CD5	CD5 Molecule	Protein Coding	4.06	DISEASES inferred ¹⁵
6	SYP	Synaptophysin	Protein Coding	3.95	DISEASES inferred ¹⁵
7	ALB	Albumin	Protein Coding	3.59	DISEASES inferred ¹⁵
8	AFP	Alpha Fetoprotein	Protein Coding	3.46	DISEASES inferred ¹⁵

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Variations for Thymus Sarcomatoid Carcinoma

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Expression for Thymus Sarcomatoid Carcinoma

Search GEO for disease gene expression data for Thymus Sarcomatoid Carcinoma.

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Pathways for Thymus Sarcomatoid Carcinoma

Pathways related to Thymus Sarcomatoid Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	FOXA2 and FOXA3 transcription factor networks ¹	10.27	ALB AFP

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GO Terms for Thymus Sarcomatoid Carcinoma

Biological processes related to Thymus Sarcomatoid Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	transport	GO:0006810	8.62	ALB AFP

Molecular functions related to Thymus Sarcomatoid Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	drug binding	GO:0008144	8.96	FOLR2 ALB
2	fatty acid binding	GO:0005504	8.62	ALB AFP

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Sources for Thymus Sarcomatoid Carcinoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia