MCID: THY017
MIFTS: 23

Thymus Sarcomatoid Carcinoma

Categories: Cancer diseases, Immune diseases

Aliases & Classifications for Thymus Sarcomatoid Carcinoma

MalaCards integrated aliases for Thymus Sarcomatoid Carcinoma:

Name: Thymus Sarcomatoid Carcinoma 12 15
Thymic Sarcomatoid Carcinoma 71
Thymic Carcinosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8138
NCIt 49 C6463
UMLS 71 C1335924

Summaries for Thymus Sarcomatoid Carcinoma

MalaCards based summary : Thymus Sarcomatoid Carcinoma, also known as thymic sarcomatoid carcinoma, is related to carcinosarcoma and spindle cell carcinoma, and has symptoms including fatigue, fever and chest pain. An important gene associated with Thymus Sarcomatoid Carcinoma is PITPNM1 (Phosphatidylinositol Transfer Protein Membrane Associated 1), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include thymus and skeletal muscle, and related phenotype is normal.

Related Diseases for Thymus Sarcomatoid Carcinoma

Diseases related to Thymus Sarcomatoid Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 carcinosarcoma 10.2
2 spindle cell carcinoma 10.0
3 sclerosing hepatic carcinoma 10.0 CD5 AFP
4 pineal region teratoma 10.0 SYP AFP
5 rectum neuroendocrine neoplasm 10.0 SYP AFP
6 ovarian germ cell teratoma 10.0 SYP AFP
7 endometrial small cell carcinoma 10.0 SYP AFP
8 pancreatic acinar cell adenocarcinoma 10.0 SYP AFP
9 tracheal lymphoma 10.0 SYP CD5
10 pineal gland cancer 10.0 SYP AFP
11 thymoma, familial 10.0
12 thymoma 10.0
13 spindle cell thymoma 10.0
14 ovarian germ cell cancer 10.0 SYP AFP
15 malignant teratoma 9.9 SYP AFP
16 pancreatoblastoma 9.9 SYP AFP
17 pancreatic endocrine carcinoma 9.9 SYP AFP
18 obstructive hydrocephalus 9.9 SYP AFP
19 mature teratoma 9.9 SYP AFP
20 pineoblastoma 9.9 SYP AFP
21 sertoli-leydig cell tumor 9.9 SYP AFP
22 leydig cell tumor 9.9 SYP AFP
23 sertoli cell tumor 9.9 SYP AFP
24 mixed cell type cancer 9.9 SYP AFP
25 acinar cell carcinoma 9.9 SYP AFP
26 cystic teratoma 9.9 SYP AFP
27 fibrolamellar carcinoma 9.9 SYP AFP
28 tubular adenocarcinoma 9.9 SYP AFP
29 benign teratoma 9.9 SYP AFP
30 thymus gland disease 9.9 SYP CD5
31 thymic carcinoma 9.9 SYP CD5
32 cavernous hemangioma 9.8 SYP AFP
33 cystadenoma 9.8 SYP AFP
34 cardiovascular organ benign neoplasm 9.8 SYP AFP
35 hepatic tuberculosis 9.8 ALB AFP
36 hepatic infarction 9.8 ALB AFP
37 hepatic coma 9.8 ALB AFP
38 hepatoid adenocarcinoma 9.8 ALB AFP
39 klatskin's tumor 9.8 ALB AFP
40 esophageal varix 9.8 ALB AFP
41 hepatorenal syndrome 9.8 ALB AFP
42 endodermal sinus tumor 9.8 ALB AFP
43 autoimmune disease of blood 9.8 CD5 ALB
44 c syndrome 9.8 ALB AFP
45 splenic disease 9.7 CD5 ALB
46 hepatic vascular disease 9.7 ALB AFP
47 plasma cell neoplasm 9.7 CD5 ALB
48 cranial nerve palsy 9.7 SYP ALB
49 metal metabolism disorder 9.7 ALB AFP
50 cecal disease 9.7 SYP ALB

Graphical network of the top 20 diseases related to Thymus Sarcomatoid Carcinoma:



Diseases related to Thymus Sarcomatoid Carcinoma

Symptoms & Phenotypes for Thymus Sarcomatoid Carcinoma

UMLS symptoms related to Thymus Sarcomatoid Carcinoma:


fatigue, fever, chest pain, coughing

MGI Mouse Phenotypes related to Thymus Sarcomatoid Carcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 9.02 ALB CD5 FOLR2 NKX6-2 SYP

Drugs & Therapeutics for Thymus Sarcomatoid Carcinoma

Search Clinical Trials , NIH Clinical Center for Thymus Sarcomatoid Carcinoma

Genetic Tests for Thymus Sarcomatoid Carcinoma

Anatomical Context for Thymus Sarcomatoid Carcinoma

MalaCards organs/tissues related to Thymus Sarcomatoid Carcinoma:

40
Thymus, Skeletal Muscle

Publications for Thymus Sarcomatoid Carcinoma

Articles related to Thymus Sarcomatoid Carcinoma:

# Title Authors PMID Year
1
Complete Resection of Thymic Sarcomatoid Carcinoma Through Total Aortic Arch Replacement. 61
27847081 2016
2
Four cases of invasive anterior mediastinal tumors definitively diagnosed by the chamberlain procedure. 61
23574996 2014
3
[Thymic sarcomatoid carcinoma; report of a case]. 61
23917062 2013
4
Multiple inflammatory cytokine-productive ThyL-6 cell line established from a patient with thymic carcinoma. 61
18691242 2008
5
Thymic sarcomatoid carcinoma with skeletal muscle differentiation: report of two cases, one with cytogenetic analysis. 61
11903597 2002

Variations for Thymus Sarcomatoid Carcinoma

Expression for Thymus Sarcomatoid Carcinoma

Search GEO for disease gene expression data for Thymus Sarcomatoid Carcinoma.

Pathways for Thymus Sarcomatoid Carcinoma

Pathways related to Thymus Sarcomatoid Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.27 ALB AFP

GO Terms for Thymus Sarcomatoid Carcinoma

Biological processes related to Thymus Sarcomatoid Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transport GO:0006810 8.62 ALB AFP

Molecular functions related to Thymus Sarcomatoid Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 8.96 FOLR2 ALB
2 fatty acid binding GO:0005504 8.62 ALB AFP

Sources for Thymus Sarcomatoid Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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