Thymus Small Cell Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Thymus Small Cell Carcinoma

MalaCards integrated aliases for Thymus Small Cell Carcinoma:

Name: Thymus Small Cell Carcinoma ¹² ¹⁵

Small Cell Carcinoma of the Thymus ¹²

Thymic Small Cell Carcinoma ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Immune diseases Endocrine diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7142

NCIt ⁴⁹ C6460

UMLS ⁷¹ C1335980

Sources

Summaries for Thymus Small Cell Carcinoma

MalaCards based summary : Thymus Small Cell Carcinoma, also known as small cell carcinoma of the thymus, is related to small cell carcinoma and vaginal glandular tumor. An important gene associated with Thymus Small Cell Carcinoma is ENPP3 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 3), and among its related pathways/superpathways is Glucose / Energy Metabolism. Affiliated tissues include thymus, lung and breast.

Sources

Related Diseases for Thymus Small Cell Carcinoma

Diseases in the Thymus Large Cell Carcinoma family:

Thymus Small Cell Carcinoma

Thymus Clear Cell Carcinoma

Diseases related to Thymus Small Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 208)

#	Related Disease	Score	Top Affiliating Genes
1	small cell carcinoma	29.2	SYP ENO2 CHGA B3GAT1
2	vaginal glandular tumor	10.3	ENO2 CHGA
3	gastric gastrinoma	10.2	ENO2 CHGA
4	goblet cell carcinoid	10.2	ENO2 CHGA
5	liver leiomyosarcoma	10.2	ENO2 CHGA
6	breast rhabdomyosarcoma	10.2	NAAA ENO2
7	appendix lymphoma	10.2	ENO2 CHGA
8	primary hepatic neuroendocrine carcinoma	10.2	SYP CHGA
9	ovarian large-cell neuroendocrine carcinoma	10.2	SYP CHGA
10	pancreas lymphoma	10.2	SYP CHGA
11	acinar cell cystadenocarcinoma	10.2	SYP CHGA
12	vulvar eccrine porocarcinoma	10.2	SYP CHGA
13	laryngeal neuroendocrine tumor	10.2	SYP CHGA
14	gastrointestinal neuroendocrine benign tumor	10.2	SYP CHGA
15	mixed ductal-endocrine carcinoma	10.2	SYP CHGA
16	papillary thymic adenocarcinoma	10.2	SYP CHGA
17	breast papillary carcinoma	10.2	SYP CHGA
18	ganglioneuroblastoma	10.2	SYP ENO2
19	vaginal tubulovillous adenoma	10.2	SYP CHGA
20	vaginal adenoma	10.2	SYP CHGA
21	esophageal adenoid cystic carcinoma	10.2	SYP CHGA
22	gastric neuroendocrine neoplasm	10.2	SYP CHGA
23	vaginal benign neoplasm	10.2	SYP CHGA
24	cervical neuroblastoma	10.2	SYP CHGA
25	pulmonary large cell neuroendocrine carcinoma	10.2	SYP CHGA
26	laryngeal small cell carcinoma	10.2	SYP CHGA
27	esophageal neuroendocrine tumor	10.2	SYP CHGA
28	malignant melanocytic neoplasm of the peripheral nerve sheath	10.2	SYP ENO2
29	pancreatic gastrinoma	10.2	SYP CHGA
30	gastrointestinal neuroendocrine tumor	10.2	SYP CHGA
31	anal neuroendocrine tumor	10.2	SYP ENO2
32	lung clear cell carcinoma	10.2	SYP CHGA
33	binswanger's disease	10.2	SYP CHGA
34	sinonasal undifferentiated carcinoma	10.2	SYP ENO2
35	chordoid meningioma	10.2	SYP CHGA
36	cerebral neuroblastoma	10.2	SYP ENO2
37	papillary tumor of the pineal region	10.2	SYP ENO2
38	pancreatic acinar cell adenocarcinoma	10.2	SYP CHGA
39	intracranial primitive neuroectodermal tumor	10.2	SYP ENO2
40	bile duct mucinous adenocarcinoma	10.2	SYP ENO2
41	nodular prostate	10.2	SYP ENO2
42	cloacogenic carcinoma	10.2	SYP ENO2
43	mature teratoma of the ovary	10.2	SYP ENO2
44	extra-adrenal pheochromocytoma	10.2	SYP CHGA
45	extraosseous ewings sarcoma-primitive neuroepithelial tumor	10.2	SYP ENO2
46	cerebellopontine angle primitive neuroectodermal	10.2	SYP ENO2
47	pulmonary neuroendocrine tumor	10.2	SYP CHGA
48	cerebellar liponeurocytoma	10.1	SYP ENO2
49	papillary ependymoma	10.1	SYP ENO2
50	optic nerve astrocytoma	10.1	SYP ENO2

Graphical network of the top 20 diseases related to Thymus Small Cell Carcinoma:

Sources

Symptoms & Phenotypes for Thymus Small Cell Carcinoma

Sources

Drugs & Therapeutics for Thymus Small Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Thymus Small Cell Carcinoma

Sources

Genetic Tests for Thymus Small Cell Carcinoma

Sources

Anatomical Context for Thymus Small Cell Carcinoma

MalaCards organs/tissues related to Thymus Small Cell Carcinoma:

⁴⁰

Thymus, Lung, Breast, Pineal, Ovary, Prostate, Appendix

Sources

Publications for Thymus Small Cell Carcinoma

Articles related to Thymus Small Cell Carcinoma:

#	Title	Authors	PMID	Year
1	Thymic small cell carcinoma associated with Lambert-Eaton myasthenic syndrome. ⁶¹	Hashimoto S...Shiono S	31586614	2019
2	GABABR-Mediated Paraneoplastic Limbic Encephalitis Due To Thymic Small Cell Carcinoma. ⁶¹	Bordin-Wosk T...Horman SF	31062226	2019
3	Thymic small cell carcinoma shows marked response to amrubicin. ⁶¹	Igawa S...Yamamoto N	19461410	2009
4	Thymic small cell carcinoma associated with pulmonary squamous cell carcinoma. ⁶¹	Iwata T...Suehiro S	17126147	2006
5	[Pathologic diagnoses of core needle biopsies of the mediastinum]. ⁶¹	Liu M...Li XH	15132850	2004
6	[Clinical study of six thymic carcinomas including long-term survivors]. ⁶¹	Tanaka A...Sato H	10319619	1999
7	Growth hormone-releasing hormone-producing tumors: clinical, biochemical, and morphological manifestations. ⁶¹	Sano T...Kovacs K	3145190	1988

Sources

Genes for Thymus Small Cell Carcinoma

Genes related to Thymus Small Cell Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ENPP3	Ectonucleotide Pyrophosphatase/Phosphodiesterase 3	Protein Coding	5.94	DISEASES inferred ¹⁵
2	NAAA	N-Acylethanolamine Acid Amidase	Protein Coding	5.89	DISEASES inferred ¹⁵
3	CHGA	Chromogranin A	Protein Coding	5.1	DISEASES inferred ¹⁵
4	ENO2	Enolase 2	Protein Coding	4.94	DISEASES inferred ¹⁵
5	SYP	Synaptophysin	Protein Coding	4.89	DISEASES inferred ¹⁵
6	CAT	Catalase	Protein Coding	4.76	DISEASES inferred ¹⁵
7	CSF3	Colony Stimulating Factor 3	Protein Coding	4.52	DISEASES inferred ¹⁵
8	B3GAT1	Beta-1,3-Glucuronyltransferase 1	Protein Coding	4.18	DISEASES inferred ¹⁵

Sources

Variations for Thymus Small Cell Carcinoma

Sources

Expression for Thymus Small Cell Carcinoma

Search GEO for disease gene expression data for Thymus Small Cell Carcinoma.

Sources

Pathways for Thymus Small Cell Carcinoma

Pathways related to Thymus Small Cell Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Glucose / Energy Metabolism ⁴	11.29	ENPP3 ENO2 CAT

Sources

GO Terms for Thymus Small Cell Carcinoma

Sources

Sources for Thymus Small Cell Carcinoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia