MCID: THY004
MIFTS: 25

Thyroid Angiosarcoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Thyroid Angiosarcoma

MalaCards integrated aliases for Thyroid Angiosarcoma:

Name: Thyroid Angiosarcoma 12 15 71
Hemangiosarcoma of the Thyroid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4514
NCIt 49 C6043
UMLS 71 C1336748

Summaries for Thyroid Angiosarcoma

Disease Ontology : 12 A thyroid sarcoma and angiosarcoma that results in a high prevalence of iodine-deficient goiter.

MalaCards based summary : Thyroid Angiosarcoma, also known as hemangiosarcoma of the thyroid, is related to thyroid gland anaplastic carcinoma and thyroid carcinoma. An important gene associated with Thyroid Angiosarcoma is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1). Affiliated tissues include thyroid, bone marrow and bone.

Related Diseases for Thyroid Angiosarcoma

Diseases related to Thyroid Angiosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 351)
# Related Disease Score Top Affiliating Genes
1 thyroid gland anaplastic carcinoma 30.0 TG PAX8 NKX2-1
2 thyroid carcinoma 30.0 TG NKX2-1 CALCA
3 angiosarcoma 29.9 VWF PECAM1 KRT7 CD34
4 thyroiditis 29.9 TG NKX2-1 CALCA
5 multinodular goiter 29.9 TG PAX8 NKX2-1 CALCA
6 goiter 29.9 TG PAX8 NKX2-1 CALCA
7 hemangioma 28.6 VWF PECAM1 NKX2-1 KRT7 CD34
8 skin epithelioid hemangioma 10.6 PECAM1 CD34
9 prostate angiosarcoma 10.5 PECAM1 CD34
10 central nervous system angiosarcoma 10.5 PECAM1 CD34
11 intravascular angioleiomyoma 10.5 PECAM1 CD34
12 heart fibrosarcoma 10.5 PECAM1 CD34
13 central nervous system hemangioma 10.5 PECAM1 CD34
14 ovarian angiosarcoma 10.5 PECAM1 CD34
15 angiomyoma 10.5 PECAM1 CD34
16 gallbladder leiomyosarcoma 10.5 PECAM1 CD34
17 hemangioma of spleen 10.5 PECAM1 CD34
18 ovary sarcoma 10.5 PECAM1 CD34
19 heart leiomyosarcoma 10.5 PECAM1 CD34
20 benign perivascular tumor 10.5 PECAM1 CD34
21 liposarcoma of bone 10.5 PECAM1 CD34
22 intravascular fasciitis 10.5 PECAM1 CD34
23 retroperitoneal hemangiopericytoma 10.5 PECAM1 CD34
24 erythema elevatum diutinum 10.5 PECAM1 CD34
25 spleen cancer 10.5 PECAM1 CD34
26 breast angiosarcoma 10.5 PECAM1 CD34
27 heart sarcoma 10.5 PECAM1 CD34
28 vulvar leiomyoma 10.5 PECAM1 CD34
29 glomeruloid hemangioma 10.5 PECAM1 CD34
30 thyroid gland mucoepidermoid carcinoma 10.5 TG CALCA
31 skin sarcoma 10.5 PECAM1 CD34
32 bacillary angiomatosis 10.5 PECAM1 CD34
33 histiocytoid hemangioma 10.5 PECAM1 CD34
34 spindle epithelial tumor with thymus-like differentiation tumor 10.5 TG CALCA
35 angiolipoma 10.5 PECAM1 CD34
36 glomangioma 10.5 PECAM1 CD34
37 angiokeratoma circumscriptum 10.5 PECAM1 CD34
38 acute thyroiditis 10.4 TG CALCA
39 fetal adenoma 10.4 TG CALCA
40 hypoadrenalism 10.4 TG CALCA
41 epithelial malignant thymoma 10.4 TG CALCA
42 gorham's disease 10.4 PECAM1 CALCA
43 subungual glomus tumor 10.4 PECAM1 CD34
44 breast sarcoma 10.4 PECAM1 CD34
45 struma ovarii 10.4 TG NKX2-1
46 glomangiomatosis 10.4 PECAM1 CD34
47 conventional angiosarcoma 10.4 PECAM1 FOXK1 CD34
48 malignant struma ovarii 10.4 TG NKX2-1
49 bartonellosis 10.4 PECAM1 CD34
50 third ventricle chordoid glioma 10.4 NKX2-1 CD34

Graphical network of the top 20 diseases related to Thyroid Angiosarcoma:



Diseases related to Thyroid Angiosarcoma

Symptoms & Phenotypes for Thyroid Angiosarcoma

Drugs & Therapeutics for Thyroid Angiosarcoma

Search Clinical Trials , NIH Clinical Center for Thyroid Angiosarcoma

Genetic Tests for Thyroid Angiosarcoma

Anatomical Context for Thyroid Angiosarcoma

MalaCards organs/tissues related to Thyroid Angiosarcoma:

40
Thyroid, Bone Marrow, Bone, Small Intestine

Publications for Thyroid Angiosarcoma

Articles related to Thyroid Angiosarcoma:

(show all 21)
# Title Authors PMID Year
1
Corrigendum to 'Primary thyroid angiosarcoma: A systematic review' [Oral Oncol. 82 (2018) 48-52]. 61
30824286 2019
2
Primary thyroid angiosarcoma: A systematic review. 61
29909901 2018
3
Primary diagnosis of angiosarcoma by fine needle aspiration: Lessons learned from 3 cases. 61
29087044 2018
4
Angioinvasion as a factor for predicting aggressive outcome in primary thyroid angiosarcoma: three case reports and literature review. 61
29895127 2018
5
Rapidly Growing Vascular Mass Within the Thyroid. Angiosarcoma. 61
26868891 2016
6
An extremely rare case of thyroid malignancy from the non-Alpine region: Angiosarcoma. 61
26741273 2016
7
Primary Thyroid Angiosarcoma with Tracheal Invasion. 61
27150873 2016
8
Electron microscopic analysis of an angiosarcoma of the thyroid from a non-Alpine endemic goiter region: A case report and brief review of the literature. 61
25289092 2014
9
Invasive thyroid angiosarcoma with a favorable outcome. 61
25745482 2014
10
[Intestinal bleeding and obstruction in the small intestine caused by metastatic thyroid angiosarcoma. Case report]. 61
24880971 2014
11
Thyroid nodule. Primary thyroid angiosarcoma. 61
24652086 2014
12
Nonalpine thyroid angiosarcoma in a patient with hashimoto thyroiditis. 61
24349811 2013
13
Non-Alpine thyroid angiosarcoma. 61
23570682 2013
14
Primary thyroid angiosarcoma: an unusual localization. 61
22553943 2012
15
Gemcitabine in advanced angiosarcoma: a retrospective case series analysis from the Italian Rare Cancer Network. 61
21464156 2012
16
Angiosarcoma of the thyroid. 61
18941766 2009
17
A case of hemangiosarcoma in thyroid with severe anemia due to bone marrow metastasis. 61
15758558 2005
18
[Epithelioid hemangiosarcoma of the thyroid gland]. 61
12061199 2002
19
Hemangiosarcoma of the Thyroid Gland. A case report. 61
11455353 2000
20
[Primary thyroid angiosarcoma]. 61
8234992 1993
21
Hemangiosarcoma of the thyroid gland. Histological diagnosis problems. 61
6199664 1983

Variations for Thyroid Angiosarcoma

Expression for Thyroid Angiosarcoma

Search GEO for disease gene expression data for Thyroid Angiosarcoma.

Pathways for Thyroid Angiosarcoma

GO Terms for Thyroid Angiosarcoma

Biological processes related to Thyroid Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.58 VWF PECAM1 F8
2 leukocyte migration GO:0050900 9.56 THBD PECAM1 CEACAM5 CD34
3 blood coagulation, intrinsic pathway GO:0007597 9.37 VWF F8
4 hemostasis GO:0007599 9.33 VWF THBD F8
5 negative regulation of blood coagulation GO:0030195 9.32 THBD CD34
6 glomerular endothelium development GO:0072011 8.96 PECAM1 CD34
7 thyroid gland development GO:0030878 8.8 TG PAX8 NKX2-1

Sources for Thyroid Angiosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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