MCID: THY004
MIFTS: 26

Thyroid Angiosarcoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Thyroid Angiosarcoma

MalaCards integrated aliases for Thyroid Angiosarcoma:

Name: Thyroid Angiosarcoma 12 15 71
Hemangiosarcoma of the Thyroid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4514
NCIt 49 C6043
UMLS 71 C1336748

Summaries for Thyroid Angiosarcoma

Disease Ontology : 12 A thyroid sarcoma and angiosarcoma that results in a high prevalence of iodine-deficient goiter.

MalaCards based summary : Thyroid Angiosarcoma, also known as hemangiosarcoma of the thyroid, is related to angiosarcoma and goiter. An important gene associated with Thyroid Angiosarcoma is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1), and among its related pathways/superpathways is Complement and coagulation cascades. Affiliated tissues include thyroid, bone marrow and bone.

Related Diseases for Thyroid Angiosarcoma

Diseases related to Thyroid Angiosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 265)
# Related Disease Score Top Affiliating Genes
1 angiosarcoma 30.8 VWF PECAM1 CD34
2 goiter 29.9 TG PAX8 NKX2-1 CALCA
3 thyroid carcinoma 29.9 TG NKX2-1 CALCA
4 thyroiditis 29.8 TG NKX2-1 CALCA
5 multinodular goiter 29.8 TG PAX8 NKX2-1 CALCA
6 hemangioma 29.5 VWF PECAM1 NKX2-1 CD34
7 thyroid gland anaplastic carcinoma 29.2 TG TERT PAX8 NKX2-1 CALCA
8 skin epithelioid hemangioma 10.5 PECAM1 CD34
9 aortic malignant tumor 10.5 PECAM1 CD34
10 prostate angiosarcoma 10.5 PECAM1 CD34
11 intravascular angioleiomyoma 10.5 PECAM1 CD34
12 heart fibrosarcoma 10.5 PECAM1 CD34
13 central nervous system hemangioma 10.5 PECAM1 CD34
14 ovarian angiosarcoma 10.5 PECAM1 CD34
15 central nervous system fibrosarcoma 10.5 FOXK1 CD34
16 angiomyoma 10.5 PECAM1 CD34
17 glomangiosarcoma 10.5 PECAM1 CD34
18 clear cell adenoma 10.5 TG PAX8
19 liposarcoma of bone 10.5 PECAM1 CD34
20 hemangioma of spleen 10.5 PECAM1 CD34
21 sclerosing liposarcoma 10.5 PAX8 CD34
22 retroperitoneal hemangiopericytoma 10.5 PECAM1 CD34
23 benign perivascular tumor 10.5 PECAM1 CD34
24 intramuscular hemangioma 10.5 PECAM1 CD34
25 sarcomatoid squamous cell skin carcinoma 10.5 PECAM1 CD34
26 breast angiosarcoma 10.5 PECAM1 CD34
27 skin sarcoma 10.5 PECAM1 CD34
28 erythema elevatum diutinum 10.5 PECAM1 CD34
29 heart sarcoma 10.5 PECAM1 CD34
30 glomeruloid hemangioma 10.5 PECAM1 CD34
31 bacillary angiomatosis 10.4 PECAM1 CD34
32 pulmonary artery leiomyosarcoma 10.4 PECAM1 CD34
33 vulvar leiomyoma 10.4 PECAM1 CD34
34 histiocytoid hemangioma 10.4 PECAM1 CD34
35 glomangioma 10.4 PECAM1 CD34
36 intravascular fasciitis 10.4 PECAM1 CD34
37 angiokeratoma circumscriptum 10.4 PECAM1 CD34
38 angiolipoma 10.4 PECAM1 CD34
39 breast sarcoma 10.4 PECAM1 CD34
40 malignant struma ovarii 10.4 TG NKX2-1
41 struma ovarii 10.4 TG NKX2-1
42 glomangiomatosis 10.4 PECAM1 CD34
43 primary congenital hypothyroidism 10.4 PAX8 NKX2-1
44 thyroid gland mucoepidermoid carcinoma 10.4 TG CALCA
45 thymus basaloid carcinoma 10.4 PAX8 NKX2-1
46 rete testis neoplasm 10.4 PAX8 NKX2-1
47 third ventricle chordoid glioma 10.4 NKX2-1 CD34
48 rete testis adenocarcinoma 10.4 PAX8 NKX2-1
49 lung meningioma 10.4 NKX2-1 CD34
50 spindle epithelial tumor with thymus-like differentiation tumor 10.4 TG CALCA

Graphical network of the top 20 diseases related to Thyroid Angiosarcoma:



Diseases related to Thyroid Angiosarcoma

Symptoms & Phenotypes for Thyroid Angiosarcoma

Drugs & Therapeutics for Thyroid Angiosarcoma

Search Clinical Trials , NIH Clinical Center for Thyroid Angiosarcoma

Genetic Tests for Thyroid Angiosarcoma

Anatomical Context for Thyroid Angiosarcoma

MalaCards organs/tissues related to Thyroid Angiosarcoma:

40
Thyroid, Bone Marrow, Bone, Small Intestine

Publications for Thyroid Angiosarcoma

Articles related to Thyroid Angiosarcoma:

(show all 22)
# Title Authors PMID Year
1
Primary Angiosarcoma of the Thyroid in an Asian Woman: A Case Report with Review of the Literature. 61
32292620 2020
2
Corrigendum to 'Primary thyroid angiosarcoma: A systematic review' [Oral Oncol. 82 (2018) 48-52]. 61
30824286 2019
3
Primary thyroid angiosarcoma: A systematic review. 61
29909901 2018
4
Primary diagnosis of angiosarcoma by fine needle aspiration: Lessons learned from 3 cases. 61
29087044 2018
5
Angioinvasion as a factor for predicting aggressive outcome in primary thyroid angiosarcoma: three case reports and literature review. 61
29895127 2018
6
Rapidly Growing Vascular Mass Within the Thyroid. Angiosarcoma. 61
26868891 2016
7
Primary Thyroid Angiosarcoma with Tracheal Invasion. 61
27150873 2016
8
An extremely rare case of thyroid malignancy from the non-Alpine region: Angiosarcoma. 61
26741273 2016
9
Electron microscopic analysis of an angiosarcoma of the thyroid from a non-Alpine endemic goiter region: A case report and brief review of the literature. 61
25289092 2014
10
Invasive thyroid angiosarcoma with a favorable outcome. 61
25745482 2014
11
[Intestinal bleeding and obstruction in the small intestine caused by metastatic thyroid angiosarcoma. Case report]. 61
24880971 2014
12
Thyroid nodule. Primary thyroid angiosarcoma. 61
24652086 2014
13
Non-Alpine thyroid angiosarcoma. 61
23570682 2013
14
Nonalpine thyroid angiosarcoma in a patient with hashimoto thyroiditis. 61
24349811 2013
15
Primary thyroid angiosarcoma: an unusual localization. 61
22553943 2012
16
Gemcitabine in advanced angiosarcoma: a retrospective case series analysis from the Italian Rare Cancer Network. 61
21464156 2012
17
Angiosarcoma of the thyroid. 61
18941766 2009
18
A case of hemangiosarcoma in thyroid with severe anemia due to bone marrow metastasis. 61
15758558 2005
19
[Epithelioid hemangiosarcoma of the thyroid gland]. 61
12061199 2002
20
Hemangiosarcoma of the Thyroid Gland. A case report. 61
11455353 2000
21
[Primary thyroid angiosarcoma]. 61
8234992 1993
22
Hemangiosarcoma of the thyroid gland. Histological diagnosis problems. 61
6199664 1983

Variations for Thyroid Angiosarcoma

Expression for Thyroid Angiosarcoma

Search GEO for disease gene expression data for Thyroid Angiosarcoma.

Pathways for Thyroid Angiosarcoma

Pathways related to Thyroid Angiosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.96 VWF THBD F8

GO Terms for Thyroid Angiosarcoma

Biological processes related to Thyroid Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 9.58 VWF PECAM1 F8
2 leukocyte migration GO:0050900 9.56 THBD PECAM1 CEACAM5 CD34
3 endothelial cell proliferation GO:0001935 9.43 CD34 CALCA
4 blood coagulation, intrinsic pathway GO:0007597 9.37 VWF F8
5 hemostasis GO:0007599 9.33 VWF THBD F8
6 negative regulation of blood coagulation GO:0030195 9.32 THBD CD34
7 glomerular endothelium development GO:0072011 8.96 PECAM1 CD34
8 thyroid gland development GO:0030878 8.8 TG PAX8 NKX2-1

Molecular functions related to Thyroid Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.1 VWF TYMS TG TERT CEACAM5 CALCA

Sources for Thyroid Angiosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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