NMTC3
MCID: THY117
MIFTS: 14

Thyroid Cancer, Nonmedullary, 3 (NMTC3)

Categories: Cancer diseases, Endocrine diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Thyroid Cancer, Nonmedullary, 3

MalaCards integrated aliases for Thyroid Cancer, Nonmedullary, 3:

Name: Thyroid Cancer, Nonmedullary, 3 58
Thyroid Cancer, Nonmedullary, 1, Formerly; Nmtc1, Formerly 58
Thyroid Cancer, Nonmedullary, 1, Formerly 58
Thyroid Carcinoma, Nonmedullary, 3 58
Nmtc1, Formerly 58
Nmtc3 58

Characteristics:

OMIM:

58
Inheritance:
autosomal dominant


HPO:

33
thyroid cancer, nonmedullary, 3:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 58 606240
MedGen 43 C4225410
SNOMED-CT via HPO 70 263681008

Summaries for Thyroid Cancer, Nonmedullary, 3

OMIM : 58 Nonmedullary thyroid cancer (NMTC) comprises thyroid cancers of follicular cell origin and accounts for more than 95% of all thyroid cancer cases. The remaining cancers originate from parafollicular cells (medullary thyroid cancer, MTC; 155240). NMTC is classified into 4 groups: papillary, follicular, Hurthle cell (607464), and anaplastic. Approximately 5% of NMTC is hereditary, occurring as a minor component of a familial cancer syndrome (e.g., familial adenomatous polyposis 175100, Carney complex 160980) or as a primary feature (familial NMTC or FNMTC). Papillary thyroid cancer (PTC) is the most common histologic subtype of FNMTC, accounting for approximately 85% of cases (summary by Vriens et al., 2009). For a general phenotypic description and a discussion of genetic heterogeneity of NMTC, see NMTC1 (188550). (606240)

MalaCards based summary : Thyroid Cancer, Nonmedullary, 3, is also known as thyroid cancer, nonmedullary, 1, formerly; nmtc1, formerly. Affiliated tissues include thyroid, and related phenotype is non-medullary thyroid carcinoma.

Related Diseases for Thyroid Cancer, Nonmedullary, 3

Symptoms & Phenotypes for Thyroid Cancer, Nonmedullary, 3

Human phenotypes related to Thyroid Cancer, Nonmedullary, 3:

33
# Description HPO Frequency HPO Source Accession
1 non-medullary thyroid carcinoma 33 HP:0040198

Symptoms via clinical synopsis from OMIM:

58
Neoplasia:
nonmedullary thyroid carcinoma (follicular)

Clinical features from OMIM:

606240

Drugs & Therapeutics for Thyroid Cancer, Nonmedullary, 3

Search Clinical Trials , NIH Clinical Center for Thyroid Cancer, Nonmedullary, 3

Genetic Tests for Thyroid Cancer, Nonmedullary, 3

Anatomical Context for Thyroid Cancer, Nonmedullary, 3

MalaCards organs/tissues related to Thyroid Cancer, Nonmedullary, 3:

42
Thyroid

Publications for Thyroid Cancer, Nonmedullary, 3

Variations for Thyroid Cancer, Nonmedullary, 3

Expression for Thyroid Cancer, Nonmedullary, 3

Search GEO for disease gene expression data for Thyroid Cancer, Nonmedullary, 3.

Pathways for Thyroid Cancer, Nonmedullary, 3

GO Terms for Thyroid Cancer, Nonmedullary, 3

Sources for Thyroid Cancer, Nonmedullary, 3

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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