MCID: THY116
MIFTS: 14

Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

MalaCards integrated aliases for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia:

Name: Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia 57
Nonmedullary Thyroid Carcinoma, with or Without Cell Oxyphilia 53 73
Thyroid Carcinoma, Nonmedullary, with Cell Oxyphilia 57 13
Tco 57 53
Tco 1 53
Tco1 57

Classifications:



External Ids:

OMIM 57 603386
MedGen 42 C1863925
UMLS 73 C1863925

Summaries for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

OMIM : 57 The familial form of nonmedullary thyroid carcinoma (NMTC) is a complex genetic disorder characterized by multifocal neoplasia and a higher degree of aggressiveness than its sporadic counterpart. One peculiar form of thyroid tumors is characterized by the presence of cell oxyphilia. Oxophil cells are found in a minority of thyroid tumors, either benign or malignant. These cells show a large volume of granular eosinophilic cytoplasm and are very rich in mitochondria. The familial occurrence of thyroid tumors with cell oxyphilia was reported by Katoh et al. (1998). Canzian et al. (1998) reported such a family with affected members in 3 generations and by linkage analysis mapped the gene to 19p13. For general phenotypic information and a discussion of genetic heterogeneity of NMTC, see 188550. (603386)

MalaCards based summary : Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia, also known as nonmedullary thyroid carcinoma, with or without cell oxyphilia, is related to thyroiditis and thyroid cancer, nonmedullary, 1. An important gene associated with Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia is TCO (Thyroid Carcinoma, Nonmedullary, With Cell Oxyphilia). Affiliated tissues include thyroid.

Related Diseases for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Diseases related to Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 thyroiditis 10.2
2 thyroid cancer, nonmedullary, 1 10.0
3 thyroid carcinoma, familial medullary 9.9
4 laryngotracheitis 9.9

Symptoms & Phenotypes for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Clinical features from OMIM:

603386

Drugs & Therapeutics for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Search Clinical Trials , NIH Clinical Center for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Genetic Tests for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Anatomical Context for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

MalaCards organs/tissues related to Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia:

41
Thyroid

Publications for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Variations for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Expression for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Search GEO for disease gene expression data for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia.

Pathways for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

GO Terms for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Sources for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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