TCO
MCID: THY116
MIFTS: 14

Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia (TCO)

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

MalaCards integrated aliases for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia:

Name: Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia 58
Nonmedullary Thyroid Carcinoma, with or Without Cell Oxyphilia 54 74
Thyroid Carcinoma, Nonmedullary, with Cell Oxyphilia 58 13
Tco 58 54
Tco 1 54
Tco1 58

Classifications:



External Ids:

OMIM 58 603386
MedGen 43 C1863925
UMLS 74 C1863925

Summaries for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

OMIM : 58 The familial form of nonmedullary thyroid carcinoma (NMTC) is a complex genetic disorder characterized by multifocal neoplasia and a higher degree of aggressiveness than its sporadic counterpart. One peculiar form of thyroid tumors is characterized by the presence of cell oxyphilia. Oxophil cells are found in a minority of thyroid tumors, either benign or malignant. These cells show a large volume of granular eosinophilic cytoplasm and are very rich in mitochondria. The familial occurrence of thyroid tumors with cell oxyphilia was reported by Katoh et al. (1998). Canzian et al. (1998) reported such a family with affected members in 3 generations and by linkage analysis mapped the gene to 19p13. For general phenotypic information and a discussion of genetic heterogeneity of NMTC, see 188550. (603386)

MalaCards based summary : Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia, also known as nonmedullary thyroid carcinoma, with or without cell oxyphilia, is related to thyroid cancer and thyroid cancer, nonmedullary, 1. An important gene associated with Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia is TCO (Thyroid Carcinoma, Nonmedullary, With Cell Oxyphilia). Affiliated tissues include thyroid.

Related Diseases for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Diseases related to Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 thyroid cancer 10.3
2 thyroid cancer, nonmedullary, 1 10.2
3 thyroid carcinoma, familial medullary 10.0
4 laryngotracheitis 10.0
5 primary hyperparathyroidism 10.0
6 hyperparathyroidism 10.0

Graphical network of the top 20 diseases related to Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia:



Diseases related to Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Symptoms & Phenotypes for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Clinical features from OMIM:

603386

Drugs & Therapeutics for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Search Clinical Trials , NIH Clinical Center for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Genetic Tests for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Anatomical Context for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

MalaCards organs/tissues related to Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia:

42
Thyroid

Publications for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Variations for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Expression for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Search GEO for disease gene expression data for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia.

Pathways for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

GO Terms for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

Sources for Thyroid Carcinoma, Nonmedullary, with or Without Cell Oxyphilia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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