MCID: THY001
MIFTS: 30

Thyroid Crisis

Categories: Endocrine diseases

Aliases & Classifications for Thyroid Crisis

MalaCards integrated aliases for Thyroid Crisis:

Name: Thyroid Crisis 12 44 15 17 70
Thyrotoxic Crisis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12837
MeSH 44 D013958
NCIt 50 C112836
SNOMED-CT 67 190262002
UMLS 70 C0040127

Summaries for Thyroid Crisis

MalaCards based summary : Thyroid Crisis, also known as thyrotoxic crisis, is related to exophthalmos and nodular goiter. An important gene associated with Thyroid Crisis is TG (Thyroglobulin), and among its related pathways/superpathways are Aldosterone synthesis and secretion and Thyroxine (Thyroid Hormone) Production. Affiliated tissues include thyroid, kidney and pituitary.

Wikipedia : 73 Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the... more...

Related Diseases for Thyroid Crisis

Diseases related to Thyroid Crisis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
# Related Disease Score Top Affiliating Genes
1 exophthalmos 30.0 TSHR TPO TG
2 nodular goiter 30.0 TSHR TPO TG
3 graves' disease 30.0 TSHR TPO TG SERPINA7
4 autoimmune polyendocrine syndrome 30.0 TPO TG
5 struma ovarii 29.9 TSHR TG
6 suppurative thyroiditis 29.8 TSHR TPO TG
7 multinodular goiter 29.8 TSHR TPO TG
8 thyroid carcinoma 29.8 TSHR TPO TG
9 acute thyroiditis 29.7 TPO TG SERPINA7
10 goiter 29.6 TSHR TPO TG SERPINA7
11 thyroiditis 29.6 TSHR TPO TG SERPINA7
12 subacute thyroiditis 29.5 TSHR TPO TG SERPINA7
13 graves disease 1 29.5 TSHR TPO TG SERPINA7 POMC
14 hashimoto thyroiditis 29.3 TSHR TPO TG SERPINA7
15 hyperthyroidism 29.2 TSHR TPO TG SERPINA7 POMC GPT
16 myxedema 28.9 TSHR TPO TG SERPINA7 POMC
17 hypothyroidism 28.7 TSHR TPO TG SERPINA7 POMC GPT
18 thyroid gland disease 28.5 TSHR TPO TG SERPINA7 POMC GPT
19 mechanical strabismus 10.2 TPO TG
20 ocular motor apraxia 10.2
21 nonencapsulated sclerosing carcinoma 10.2 TPO TG
22 aspirin allergy 10.2 TPO TG
23 postsurgical hypothyroidism 10.2 TPO TG
24 goiter, multinodular 1, with or without sertoli-leydig cell tumors 10.2 TPO TG
25 athyreosis 10.1 TSHR TG
26 type 1 diabetes mellitus 20 10.1 TPO TG
27 transient congenital hypothyroidism 10.1 TSHR TPO
28 papillary thyroid microcarcinoma 10.1 TSHR TG
29 benign struma ovarii 10.1 TSHR TG
30 orbital disease 10.1 TSHR TG
31 pernicious anemia 10.1 TPO TG
32 rare hyperthyroidism 10.1
33 hypotropia 10.1 TSHR TPO
34 hypothyroidism, congenital, nongoitrous, 1 10.1 TSHR TG
35 ovarian serous adenofibroma 10.1 TG POMC
36 hypothyroidism, congenital, nongoitrous, 2 10.1 TSHR TG
37 anal spasm 10.1 TG POMC
38 pre-eclampsia 10.1
39 eclampsia 10.1
40 corticosteroid-binding globulin deficiency 10.1 SERPINA7 POMC
41 chronic urticaria 10.1 TPO TG
42 thyroid cancer, nonmedullary, 2 10.1 TSHR TG
43 allan-herndon-dudley syndrome 10.1 SLC16A10 SERPINA7
44 thyroid gland medullary carcinoma 10.1 TG POMC
45 metabolic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 10.0
46 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 10.0
47 hypoglycemia 10.0
48 postpartum depression 10.0 TPO POMC
49 thyroid carcinoma, familial medullary 10.0 TG POMC
50 precocious puberty, male-limited 10.0 TSHR POMC

Graphical network of the top 20 diseases related to Thyroid Crisis:



Diseases related to Thyroid Crisis

Symptoms & Phenotypes for Thyroid Crisis

Drugs & Therapeutics for Thyroid Crisis

Search Clinical Trials , NIH Clinical Center for Thyroid Crisis

Inferred drug relations via UMLS 70 / NDF-RT 51 :


Methimazole
Propylthiouracil

Cochrane evidence based reviews: thyroid crisis

Genetic Tests for Thyroid Crisis

Anatomical Context for Thyroid Crisis

MalaCards organs/tissues related to Thyroid Crisis:

40
Thyroid, Kidney, Pituitary, Cortex, Thymus, Adrenal Gland, Heart

Publications for Thyroid Crisis

Articles related to Thyroid Crisis:

(show top 50) (show all 389)
# Title Authors PMID Year
1
Thyroid crisis mimicking clinically mild encephalitis/encephalopathy with a reversible splenial lesion: A pediatric case report. 61
33408037 2021
2
Preoperative plasmapheresis in patients with Graves' disease intolerant to antithyroid drugs. 61
33661574 2021
3
Short-Term Outcomes of Surgery for Graves' Disease in Germany. 61
33322553 2020
4
Thyrotoxic Crisis and COVID-19 Infection: An Extraordinary Case and Literature Review. 61
33282582 2020
5
A case in which SGLT2 inhibitor is a contributing factor to takotsubo cardiomyopathy and heart failure. 61
33014200 2020
6
Recurrent Thyroid Storm Caused by a Complete Hydatidiform Mole in a Perimenopausal Woman. 61
33425402 2020
7
Malignant Arrhythmias as the Unmasked Manifestation of Thyroid Storm. 61
33061537 2020
8
Immune checkpoint inhibitor-associated thyroid dysfunction: a disproportionality analysis using the WHO Adverse Drug Reaction Database, VigiBase. 61
31648184 2020
9
Intramuscular levothyroxine: a solution to a mental health related thyroid crisis. 61
31434663 2019
10
Thyroid emergencies. 61
31237256 2019
11
Management of Endocrine Emergencies in the ICU. 61
30852927 2019
12
Thyroidectomy Then and Now: A 50-Year Australian Perspective. 61
30536022 2019
13
Weathering the Crisis: A Case of Thyroid Crisis with Propranolol-Induced Circulatory Collapse Successfully Treated with Therapeutic Plasma Exchange. 61
33442157 2019
14
A rare complication of bedside tracheotomy: Thyroid crisis. 61
30604713 2019
15
A Rare Case of Thyrotropin-Secreting Pituitary Adenoma Coexisting with Papillary Thyroid Carcinoma Presenting with Visual Disturbance without Hyperthyroidism. 61
30096503 2018
16
Diltiazem-Associated Cardiogenic Shock in Thyrotoxic Crisis. 61
29521654 2018
17
Diabetic ketoacidosis and thyroid storm: coexistence of a double trouble. 61
30262530 2018
18
Thyrotoxic crisis as an acute clinical presentation in a child. 61
29574428 2018
19
Iodinated Contrast Administration Resulting in Cardiogenic Shock in Patient with Uncontrolled Graves Disease. 61
29102101 2017
20
Acute severe asthma with thyroid crisis and myasthenia: a case report and literature review. 61
26471346 2017
21
Propranolol-Induced Circulatory Collapse in a Patient With Thyroid Crisis and Underlying Thyrocardiac Disease: A Word of Caution. 61
29318163 2017
22
Anaesthetic Implications of Severe Hyperthyroidism Secondary to Molar Pregnancy: A Case Report and Review of Literature. 61
29284889 2017
23
Thyroid Crisis in a Patient With Burn Injury. 61
28157789 2017
24
Thyrotoxic and pheochromocytoma multisystem crisis: a case report. 61
28641581 2017
25
Subacute thyroiditis causing thyrotoxic crisis; a case report with literature review. 61
28399492 2017
26
Jaundice Heralding the Onset of Thyrotoxic Crisis. 61
27762123 2016
27
Cardiac arrest caused by landiolol in a patient in thyroid crisis. 61
30546666 2016
28
Thyrotoxic crisis presenting with jaundice. 61
27338936 2016
29
Informed Consent in Contrast-Enhanced CT: Understanding of Risks and Identification of Possible Prognostic Factors. 61
26509561 2015
30
Trauma triggering thyrotoxic crisis with lactic acidosis. 61
26604530 2015
31
MISSING THE OBVIOUS: A CASE OF UNDIAGNOSED GRAVES' DISEASE. 61
27159484 2015
32
Onset of reversible flaccid quadriplegia during treatment of thyrotoxic crisis. 61
25748960 2015
33
Out of the blue! Thyroid crisis. 61
25886440 2015
34
[Prolonged psychosis associated with thyrotoxicosis during the subacute stage of cardioembolic stroke in a patient with untreated basedow disease]. 61
25475038 2014
35
[Oedema and haemorrhagic diathesis in a 50-year-old woman with thyrotoxicosis]. 61
25056734 2014
36
Thyroid crisis in the maxillofacial trauma patient. 61
25085805 2014
37
Jod-Basedow effect due to prolonged use of lugol solution-case report. 61
25581962 2014
38
Sudden unexpected death in the setting of undiagnosed Graves' disease. 61
24880878 2014
39
Acute pericarditis: unique comorbidity of thyrotoxic crisis with Graves' disease. 61
24411211 2014
40
Glucose variability before and after treatment of a patient with Graves' disease complicated by diabetes mellitus: assessment by continuous glucose monitoring. 61
24420389 2014
41
[Anesthetic and perioperative management of a patient with uncontrolled thyrotoxicosis undergoing coronary artery bypass grafting surgery]. 61
24228459 2013
42
Impact of neuromonitoring of recurrent laryngeal nerve and surgical loupes on the outcome of thyroidectomy. A retrospective chart review. 61
23974454 2013
43
A case of graves' disease diagnosed in the course of bilateral carotid artery stenoses (moyamoya disease); a case report and review of the literature. 61
23966756 2013
44
Endocrine-related diseases in the emergency unit of a Tertiary Health Care Center in Lagos: A study of the admission and mortality patterns. 61
24249952 2013
45
[Cardiac arrest and cardial insuffiency as result of thyrotoxicosis]. 61
23582070 2013
46
Neo-endocrinochemotherapy: a novel approach for enhancing chemotherapeutic efficacy in clinic? 61
23375412 2013
47
Maximinus Daia, a Roman emperor who may have had Graves' disease and died of a thyrotoxic crisis. 61
23624140 2013
48
Successful treatment of thyroid crisis accompanied by hypoglycemia, lactic acidosis, and multiple organ failure. 61
22386356 2012
49
An unusual cause of flash pulmonary oedema. 61
22707683 2012
50
Successful treatment of thyrotoxic crisis after esophagectomy in an elderly woman with hyperthyroidism. 61
22632530 2012

Variations for Thyroid Crisis

Expression for Thyroid Crisis

Search GEO for disease gene expression data for Thyroid Crisis.

Pathways for Thyroid Crisis

Pathways related to Thyroid Crisis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.12 TSHR TPO TG SERPINA7 POMC
2 9.58 TSHR TPO TG

GO Terms for Thyroid Crisis

Cellular components related to Thyroid Crisis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 TPO TG SERPINA7 POMC GPT CTSH

Biological processes related to Thyroid Crisis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone biosynthetic process GO:0042446 9.16 TPO TG
2 thyroid hormone transport GO:0070327 8.96 SLC16A10 SERPINA7
3 thyroid hormone generation GO:0006590 8.8 TPO TG SLC16A10

Sources for Thyroid Crisis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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