PLAT
MCID: THY020
MIFTS: 23

Thyroid Hyalinizing Trabecular Adenoma (PLAT)

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Thyroid Hyalinizing Trabecular Adenoma

MalaCards integrated aliases for Thyroid Hyalinizing Trabecular Adenoma:

Name: Thyroid Hyalinizing Trabecular Adenoma 12 72
Plat 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6203
NCIt 50 C6846
UMLS 72 C1336751

Summaries for Thyroid Hyalinizing Trabecular Adenoma

MalaCards based summary : Thyroid Hyalinizing Trabecular Adenoma, also known as plat, is related to thyroid cancer, nonmedullary, 1 and papillary carcinoma. An important gene associated with Thyroid Hyalinizing Trabecular Adenoma is CALCA (Calcitonin Related Polypeptide Alpha). The drugs Dexamethasone acetate and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include thyroid, t cells and lung.

Related Diseases for Thyroid Hyalinizing Trabecular Adenoma

Diseases related to Thyroid Hyalinizing Trabecular Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 thyroid cancer, nonmedullary, 1 10.2
2 papillary carcinoma 10.2
3 thyroid gland papillary carcinoma 10.2
4 adenoma 10.2
5 thyroiditis 10.2

Graphical network of the top 20 diseases related to Thyroid Hyalinizing Trabecular Adenoma:



Diseases related to Thyroid Hyalinizing Trabecular Adenoma

Symptoms & Phenotypes for Thyroid Hyalinizing Trabecular Adenoma

Drugs & Therapeutics for Thyroid Hyalinizing Trabecular Adenoma

Drugs for Thyroid Hyalinizing Trabecular Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 73)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
2
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
3
Vincristine Approved, Investigational Phase 3 57-22-7, 2068-78-2 5978
4
Melphalan Approved Phase 3 148-82-3 460612 4053
5
Doxorubicin Approved, Investigational Phase 3 23214-92-8 31703
6
Levoleucovorin Approved, Investigational Phase 3 68538-85-2
7
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 5310940 9887054 43805 6857599
8
leucovorin Approved Phase 3 58-05-9 143 6006
9
Irinotecan Approved, Investigational Phase 3 100286-90-6, 97682-44-5 60838
10 Hormone Antagonists Phase 3
11 Antiemetics Phase 3
12 Alkylating Agents Phase 3
13 Gastrointestinal Agents Phase 3
14 Antineoplastic Agents, Phytogenic Phase 3
15 Angiogenesis Inhibitors Phase 3
16 HIV Protease Inhibitors Phase 3
17
Liposomal doxorubicin Phase 3 31703
18
protease inhibitors Phase 3
19 Hormones Phase 3
20 Peripheral Nervous System Agents Phase 3
21 glucocorticoids Phase 3
22 Anti-Bacterial Agents Phase 3
23 Angiogenesis Modulating Agents Phase 3
24 Anti-Inflammatory Agents Phase 3
25 Tubulin Modulators Phase 3
26 Antineoplastic Agents, Hormonal Phase 3
27 Antibiotics, Antitubercular Phase 3
28 Antimitotic Agents Phase 3
29 Autonomic Agents Phase 3
30 BB 1101 Phase 3
31 Antirheumatic Agents Phase 3
32 Antineoplastic Agents, Alkylating Phase 3
33 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
34 Topoisomerase Inhibitors Phase 3
35
s 1 (combination) Phase 3
36 Antidotes Phase 3
37 topoisomerase I inhibitors Phase 3
38 Protective Agents Phase 3
39
Fluorouracil Approved Phase 2 51-21-8 3385
40
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
41
Gemcitabine Approved Phase 2 95058-81-4 60750
42
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
43
Pancrelipase Approved, Investigational Phase 2 53608-75-6
44
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
45
Volociximab Investigational Phase 1, Phase 2 558480-40-3
46 taxane Phase 1, Phase 2
47 Antibodies Phase 1, Phase 2
48 Immunoglobulins Phase 1, Phase 2
49 Antibodies, Monoclonal Phase 1, Phase 2
50 Protein Kinase Inhibitors Phase 2

Interventional clinical trials:

(show all 17)
# Name Status NCT ID Phase Drugs
1 Multiple Myeloma Treatment With Thalidomide. Three Randomized Studies on Thalidomide as Induction Treatment Before Autotransplant (MY-TAG) or With a Conventional Chemotherapy (MY-DECT) and as Consolidation/Maintenance at Plateau Phase (MY-PLAT). Completed NCT01070862 Phase 3 Thalidomide, Dexamethasone;Vincristin , Adriamycin, Dexamethasone = VAD;Thalidomide, melphalan, endoxan, dexamethasone (MCDex-Thal);melphalan, endoxan, dexamethasone (MCDex);Thalidomide, Dexamethasone
2 Irinotecan Combined With S-1( IRIS ) Followed by mFOLFOX6 Regimen Versus mFOLFOX6 Followed by IRIS Regimen in Advanced Colorectal Cancer Suspended NCT00316745 Phase 3 Campto, Topotesin;TS-1;L-Plat;Isovorin;5-FU
3 A Phase I-II Synchrotron Radiation Application to the Treatment of Intracranial Tumors Unknown status NCT01640509 Phase 1, Phase 2
4 A Phase 1/2, Open-Label, Adaptive, Randomized Study of Liposomal Doxorubicin With or Without M200 (Volociximab) for the Treatment of Subjects With Advanced Epithelial Ovarian Cancer or Primary Peritoneal Cancer That Have Relapsed After Prior Therapy With a Platinum/Taxane-Based Chemotherapy Completed NCT00635193 Phase 1, Phase 2 M200 (Volociximab);Liposomal Doxorubicin;M200 (Volociximab);M200 (Volociximab)
5 Phase II Study of RADPLAT and Tarceva in Locally Advanced Head and Neck Squamous Cell Carcinoma (SCCA) Completed NCT00304278 Phase 2 Erlotinib (Tarceva);Intra-arterial Cisplatin (PLAT)
6 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-06: A Phase 1/2 Study of CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma Recruiting NCT03684889 Phase 1, Phase 2
7 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-02: A Phase 1/2 Feasibility and Safety Study of CD19-CAR T Cell Immunotherapy for CD19+ Leukemia Recruiting NCT02028455 Phase 1, Phase 2
8 Definitive Chemoradiation With Gemcitabine and Continuous 5- FU (Fluorouracil)Followed by High Dose Rate Brachytherapy or Stereotactic Body Radiation Therapy Boost in Locally Advanced Intra or Extrahepatic Cholangiocarcinoma Terminated NCT00983541 Phase 2 Fluorouracil (5-FU);Gemcitabine
9 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-03: A Pilot Feasibility and Safety Study of CD19t T-Antigen Presenting Cells (T-APCs) Following CAR T Cell Immunotherapy for CD19+ Leukemia Recruiting NCT03186118 Phase 1
10 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-05: A Phase 1 Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Leukemia Recruiting NCT03330691 Phase 1
11 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-04: A Phase 1 Feasibility and Safety Study of CD22-CAR T Cell Immunotherapy for CD22+ Leukemia and Lymphoma Active, not recruiting NCT03244306 Phase 1
12 Pediatric Leukemia Adoptive Therapy (PLAT)-01: A Phase 1 Feasibility and Safety Study of Cellular Immunotherapy for Relapsed Pediatric CD19+ Acute Lymphoblastic Leukemia Using Autologous T-cells Lentivirally Transduced To Express a CD19-Specific Chimeric Antigen Receptor Active, not recruiting NCT01683279 Phase 1
13 A Prospective Randomized Trial of Surgical Resection Versus Percutaneous Local Ablative Therapy for Hepatocellular Carcinoma Complicating Clinically Significant Portal Hypertension Within the Milan Criteria Unknown status NCT01860222
14 Mini Incision Dynamic Hip Screw Technique Completed NCT03070418
15 Independent Predictors of Mortality in Polytrauma Patients: a Prospective, Observational, Longitudinal Study Completed NCT01669577
16 Venous Thromboembolism in Myotonic Dystrophy Type 1 Recruiting NCT03424460
17 TVT-ABBREVO Versus SERASIS for the Treatment of Female Urinary Stress Incontinence: 1 Year Outcomes of a Comparative Study With 2 Trans-obturator Sub Mid Urethral Slings Active, not recruiting NCT02867748

Search NIH Clinical Center for Thyroid Hyalinizing Trabecular Adenoma

Genetic Tests for Thyroid Hyalinizing Trabecular Adenoma

Anatomical Context for Thyroid Hyalinizing Trabecular Adenoma

MalaCards organs/tissues related to Thyroid Hyalinizing Trabecular Adenoma:

41
Thyroid, T Cells, Lung, Breast, Liver, Endothelial, Prostate

Publications for Thyroid Hyalinizing Trabecular Adenoma

Articles related to Thyroid Hyalinizing Trabecular Adenoma:

(show top 50) (show all 389)
# Title Authors PMID Year
1
Synthesis and anti-nociceptive potential of isoxazole carboxamide derivatives. 38
31355366 2019
2
Disordered APC/C-mediated cell cycle progression and IGF1/PI3K/AKT signalling are the potential basis of Sertoli cell-only syndrome. 38
30995700 2019
3
Driving Pressure: Defining the Range. 38
31088990 2019
4
PEEP titration in moderate to severe ARDS: plateau versus transpulmonary pressure. 38
31312921 2019
5
The Nodule-Specific PLAT Domain Protein NPD1 Is Required for Nitrogen-Fixing Symbiosis. 38
31061106 2019
6
Plasminogen activator, tissue type regulates germinal vesicle breakdown and cumulus expansion of bovine cumulus-oocyte complex in vitro†. 38
30939202 2019
7
Association Analysis of Charcoal Rot Disease Resistance in Soybean. 38
31244565 2019
8
Comparing the effect of tempe flour and tofu flour consumption on estrogen serum in ovariectomized rats. 38
31245636 2019
9
Nodule-specific PLAT domain proteins are expanded in the Medicago lineage and required for nodulation. 38
30664233 2019
10
Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study. 38
30790030 2019
11
From clinic to mechanism: Proteomics-based assessment of angiogenesis in adrenal pheochromocytoma. 38
31106414 2019
12
Profiling of Alzheimer's disease related genes in mild to moderate vitamin D hypovitaminosis. 38
30889441 2019
13
Laboratory Investigation on the Shrinkage Cracking of Waste Fiber-Reinforced Recycled Aggregate Concrete. 38
31013758 2019
14
Investigations on the Role of the Fibrinolytic Pathway on Outflow Facility Regulation. 38
30995314 2019
15
Comment on 'Ambulance dispatch versus GP home visit for highly urgent out-of-hours primary care' by Plat et al. 38
30346509 2019
16
Effects of Sprint-Interval and Endurance Respiratory Muscle Training Regimens. 38
30216239 2019
17
An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. 38
30504459 2019
18
Application of alveolar recruitment strategy and positive end-expiratory pressure combined with autoflow in the one-lung ventilation during thoracic surgery in obese patients. 38
30962992 2019
19
Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture. 38
30635013 2019
20
Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions. 38
31105713 2019
21
Identification of hub genes and analysis of prognostic values in pancreatic ductal adenocarcinoma by integrated bioinformatics methods. 38
30173393 2018
22
Role of the tissue-type plasminogen activator -7351C > T and plasminogen activator inhibitor 1 4G/5G gene polymorphisms in central serous chorioretinopathy. 38
30442055 2018
23
Transcriptomic Plasticity in the Arthropod Generalist Tetranychus urticae Upon Long-Term Acclimation to Different Host Plants. 38
30333191 2018
24
Identification and prediction of novel non-coding and coding RNA-associated competing endogenous RNA networks in colorectal cancer. 38
30581274 2018
25
In vitro study of HAX1 gene therapy by retro viral transduction as a therapeutic target in severe congenital neutropenia. 38
30698159 2018
26
Superovulation alters the expression of endometrial genes critical to tissue remodeling and placentation. 38
29959621 2018
27
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells. 38
30394400 2018
28
Structure of the human PKD1-PKD2 complex. 38
30093605 2018
29
DNA Methylation of Proximal PLAT Promoter in Chronic Rhinosinusitis With Nasal Polyps. 38
29962211 2018
30
Plasminogen activator system homeostasis and its dysregulation by ethanol in astrocyte cultures and the developing brain. 38
29885422 2018
31
Time to plateau as a predictor of survival in newly diagnosed multiple myeloma. 38
29659048 2018
32
Analyzing the molecular mechanism of the tissue specificity of gastrointestinal stromal tumors by using bioinformatics approaches. 38
30358224 2018
33
Predictive value of the pendulum test for assessing knee extensor spasticity. 38
30021641 2018
34
PAI1 blocks NMDA receptor-mediated effects of tissue-type plasminogen activator on cell signaling and physiology. 38
29930084 2018
35
[MicroRNA in Body Fluids - Development of the Novel Plat Form for Cancer Therapeutics and Diagnosis]. 38
30026410 2018
36
Effects of biochar application on the abundance and community composition of denitrifying bacteria in a reclaimed soil from coal mining subsidence area. 38
29996418 2018
37
Feasibility and safety of low-flow extracorporeal CO2 removal managed with a renal replacement platform to enhance lung-protective ventilation of patients with mild-to-moderate ARDS. 38
29743094 2018
38
Mutation burden profile in familial Alzheimer's disease cases from India. 38
29329714 2018
39
Confirming Maximal Oxygen Uptake: Is Heart Rate the Answer? 38
29365339 2018
40
Comparison of three assembly strategies for a heterozygous seedless grapevine genome assembly. 38
29343235 2018
41
Correction to: Effectiveness of Exercise Interventions to Improve Postural Control in Older Adults: A Systematic Review and Meta-Analyses of Centre of Pressure Measurements. 38
29052804 2018
42
Assessment of Bronchial Obstruction Using Lateral Pressure Measurement during Bronchoscopy. 38
29190612 2018
43
In-vitro analysis of Quantum Molecular Resonance effects on human mesenchymal stromal cells. 38
29293552 2018
44
Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy. 38
30687812 2018
45
Using Cellulolytic Nitrogen Fixing Bacterium, Azomonas agilis for Effective Degradation of Agricultural Residues. 38
29997700 2018
46
[The comparison of clinical features and laboratory indexes between flat descending hearing loss and total hearing loss]. 38
29798311 2017
47
ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT. 38
29118335 2017
48
Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome. 38
28936695 2017
49
Hypothermia induced by anesthesia regulates various signals expressions in the hippocampus of animals. 38
28938523 2017
50
Gene expression profiling of upregulated mRNAs in granulosa cells of bovine ovulatory follicles following stimulation with hCG. 38
29100496 2017

Variations for Thyroid Hyalinizing Trabecular Adenoma

Expression for Thyroid Hyalinizing Trabecular Adenoma

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GO Terms for Thyroid Hyalinizing Trabecular Adenoma

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