PLAT
MCID: THY020
MIFTS: 21

Thyroid Hyalinizing Trabecular Adenoma (PLAT)

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Thyroid Hyalinizing Trabecular Adenoma

MalaCards integrated aliases for Thyroid Hyalinizing Trabecular Adenoma:

Name: Thyroid Hyalinizing Trabecular Adenoma 12 71
Plat 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6203
NCIt 49 C6846
SNOMED-CT 67 722214003
UMLS 71 C1336751

Summaries for Thyroid Hyalinizing Trabecular Adenoma

MalaCards based summary : Thyroid Hyalinizing Trabecular Adenoma, also known as plat, is related to thyroid cancer, nonmedullary, 1 and adenoma. The drugs Vincristine and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include thyroid, t cells and lung.

Related Diseases for Thyroid Hyalinizing Trabecular Adenoma

Diseases related to Thyroid Hyalinizing Trabecular Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 thyroid cancer, nonmedullary, 1 10.2
2 adenoma 10.2

Symptoms & Phenotypes for Thyroid Hyalinizing Trabecular Adenoma

Drugs & Therapeutics for Thyroid Hyalinizing Trabecular Adenoma

Drugs for Thyroid Hyalinizing Trabecular Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 68)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vincristine Approved, Investigational Phase 3 57-22-7, 2068-78-2 5978
2
Doxorubicin Approved, Investigational Phase 3 23214-92-8 31703
3
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
4
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
5
Melphalan Approved Phase 3 148-82-3 460612 4053
6
Levoleucovorin Approved, Investigational Phase 3 68538-85-2
7
leucovorin Approved Phase 3 58-05-9 6006 143
8
Irinotecan Approved, Investigational Phase 3 97682-44-5, 100286-90-6 60838
9
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 43805 6857599 5310940 9887054
10
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
11 Gastrointestinal Agents Phase 3
12 Hormones Phase 3
13 Angiogenesis Inhibitors Phase 3
14 Antineoplastic Agents, Hormonal Phase 3
15 Alkylating Agents Phase 3
16 Antiemetics Phase 3
17 Hormone Antagonists Phase 3
18
protease inhibitors Phase 3
19 Anti-Bacterial Agents Phase 3
20 HIV Protease Inhibitors Phase 3
21
Liposomal doxorubicin Phase 3 31703
22 Tubulin Modulators Phase 3
23 glucocorticoids Phase 3
24 BB 1101 Phase 3
25 Antirheumatic Agents Phase 3
26 Antibiotics, Antitubercular Phase 3
27 Anti-Inflammatory Agents Phase 3
28 Antimitotic Agents Phase 3
29 Micronutrients Phase 3
30 Vitamins Phase 3
31 Vitamin B Complex Phase 3
32 Antidotes Phase 3
33 Folate Phase 3
34 Nutrients Phase 3
35 Trace Elements Phase 3
36 Vitamin B9 Phase 3
37 topoisomerase I inhibitors Phase 3
38 Protective Agents Phase 3
39
Fluorouracil Approved Phase 2 51-21-8 3385
40
Cisplatin Approved Phase 2 15663-27-1 2767 441203 84093
41
Gemcitabine Approved Phase 2 95058-81-4 60750
42
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
43
Pancrelipase Approved, Investigational Phase 2 53608-75-6
44
Carboplatin Approved Phase 2 41575-94-4 10339178 38904 498142
45
Volociximab Investigational Phase 1, Phase 2 558480-40-3
46 Immunoglobulins Phase 1, Phase 2
47 taxane Phase 1, Phase 2
48 Antibodies Phase 1, Phase 2
49 Antibodies, Monoclonal Phase 1, Phase 2
50 Protein Kinase Inhibitors Phase 2

Interventional clinical trials:

(show all 17)
# Name Status NCT ID Phase Drugs
1 Multiple Myeloma Treatment With Thalidomide. Three Randomized Studies on Thalidomide as Induction Treatment Before Autotransplant (MY-TAG) or With a Conventional Chemotherapy (MY-DECT) and as Consolidation/Maintenance at Plateau Phase (MY-PLAT). Completed NCT01070862 Phase 3 Thalidomide, Dexamethasone;Vincristin , Adriamycin, Dexamethasone = VAD;Thalidomide, melphalan, endoxan, dexamethasone (MCDex-Thal);melphalan, endoxan, dexamethasone (MCDex);Thalidomide, Dexamethasone
2 Irinotecan Combined With S-1( IRIS ) Followed by mFOLFOX6 Regimen Versus mFOLFOX6 Followed by IRIS Regimen in Advanced Colorectal Cancer Suspended NCT00316745 Phase 3 Campto, Topotesin;TS-1;L-Plat;Isovorin;5-FU
3 A Phase I-II Synchrotron Radiation Application to the Treatment of Intracranial Tumors Unknown status NCT01640509 Phase 1, Phase 2
4 A Phase 1/2, Open-Label, Adaptive, Randomized Study of Liposomal Doxorubicin With or Without M200 (Volociximab) for the Treatment of Subjects With Advanced Epithelial Ovarian Cancer or Primary Peritoneal Cancer That Have Relapsed After Prior Therapy With a Platinum/Taxane-Based Chemotherapy Completed NCT00635193 Phase 1, Phase 2 M200 (Volociximab);Liposomal Doxorubicin;M200 (Volociximab);M200 (Volociximab)
5 Phase II Study of RADPLAT and Tarceva in Locally Advanced Head and Neck Squamous Cell Carcinoma (SCCA) Completed NCT00304278 Phase 2 Erlotinib (Tarceva);Intra-arterial Cisplatin (PLAT)
6 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-02: A Phase 1/2 Feasibility and Safety Study of CD19-CAR T Cell Immunotherapy for CD19+ Leukemia Recruiting NCT02028455 Phase 1, Phase 2
7 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-06: A Phase 1/2 Study of CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma Active, not recruiting NCT03684889 Phase 1, Phase 2
8 Definitive Chemoradiation With Gemcitabine and Continuous 5- FU (Fluorouracil)Followed by High Dose Rate Brachytherapy or Stereotactic Body Radiation Therapy Boost in Locally Advanced Intra or Extrahepatic Cholangiocarcinoma Terminated NCT00983541 Phase 2 Fluorouracil (5-FU);Gemcitabine
9 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-03: A Pilot Feasibility and Safety Study of CD19t T-Antigen Presenting Cells (T-APCs) Following CAR T Cell Immunotherapy for CD19+ Leukemia Recruiting NCT03186118 Phase 1
10 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-05: A Phase 1 Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Leukemia Active, not recruiting NCT03330691 Phase 1
11 Pediatric and Young Adult Leukemia Adoptive Therapy (PLAT)-04: A Phase 1 Feasibility and Safety Study of CD22-CAR T Cell Immunotherapy for CD22+ Leukemia and Lymphoma Active, not recruiting NCT03244306 Phase 1
12 Pediatric Leukemia Adoptive Therapy (PLAT)-01: A Phase 1 Feasibility and Safety Study of Cellular Immunotherapy for Relapsed Pediatric CD19+ Acute Lymphoblastic Leukemia Using Autologous T-cells Lentivirally Transduced To Express a CD19-Specific Chimeric Antigen Receptor Active, not recruiting NCT01683279 Phase 1
13 A Prospective Randomized Trial of Surgical Resection Versus Percutaneous Local Ablative Therapy for Hepatocellular Carcinoma Complicating Clinically Significant Portal Hypertension Within the Milan Criteria Unknown status NCT01860222
14 TVT-ABBREVO Versus SERASIS for the Treatment of Female Urinary Stress Incontinence: 1 Year Outcomes of a Comparative Study With 2 Trans-obturator Sub Mid Urethral Slings Unknown status NCT02867748
15 Mini Incision Dynamic Hip Screw Technique Completed NCT03070418
16 Independent Predictors of Mortality in Polytrauma Patients: a Prospective, Observational, Longitudinal Study Completed NCT01669577
17 Venous Thromboembolism in Myotonic Dystrophy Type 1 Recruiting NCT03424460

Search NIH Clinical Center for Thyroid Hyalinizing Trabecular Adenoma

Genetic Tests for Thyroid Hyalinizing Trabecular Adenoma

Anatomical Context for Thyroid Hyalinizing Trabecular Adenoma

MalaCards organs/tissues related to Thyroid Hyalinizing Trabecular Adenoma:

40
Thyroid, T Cells, Lung, Breast, Liver, Endothelial, Kidney

Publications for Thyroid Hyalinizing Trabecular Adenoma

Articles related to Thyroid Hyalinizing Trabecular Adenoma:

(show top 50) (show all 410)
# Title Authors PMID Year
1
Lily steroidal glycoalkaloid promotes early inflammatory resolution in wounded human fibroblasts. 61
32194231 2020
2
Expression profiles of the internal jugular and saphenous veins: Focus on hemostasis genes. 61
32438216 2020
3
Postural data from Stargardt's syndrome patients. 61
32280738 2020
4
Changes in the concentrations of mediators in exhaled breath condensate during cardiac valve replacement under cardiopulmonary bypass and their relations with postoperative acute respiratory distress syndrome. 61
32481266 2020
5
Duration of prone position sessions: a prospective cohort study. 61
32449068 2020
6
Transcriptomic Response of Breast Cancer Cells MDA-MB-231 to Docosahexaenoic Acid: Downregulation of Lipid and Cholesterol Metabolism Genes and Upregulation of Genes of the Pro-Apoptotic ER-Stress Pathway. 61
32466294 2020
7
Outdoor cultivation of Chlorella sp. in an improved thin-film flat-plate photobioreactor in desertification areas. 61
31926816 2020
8
Layered Ca0.28 MnO2 ·0.5H2 O as a High Performance Cathode for Aqueous Zinc-Ion Battery. 61
32249537 2020
9
Therapeutic options for advanced epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer: a Bayesian network secondary analysis. 61
32324592 2020
10
Knockdown of PLAT enhances the anticancer effect of gefitinib in non-small cell lung cancer. 61
32274137 2020
11
Quantitative proteomics discloses monacolin K-induced alterations in triple-negative breast cancer cell proteomes and phosphoproteomes. 61
31859329 2020
12
A Select and Resequence Approach Reveals Strain-Specific Effects of Medicago Nodule-Specific PLAT-Domain Genes. 61
31653715 2020
13
Flow-controlled ventilation (FCV) improves regional ventilation in obese patients - a randomized controlled crossover trial. 61
31992213 2020
14
Respiratory parameters and acute kidney injury in acute respiratory distress syndrome: a causal inference study. 61
32042758 2019
15
Synthesis and anti-nociceptive potential of isoxazole carboxamide derivatives. 61
31355366 2019
16
From clinic to mechanism: Proteomics-based assessment of angiogenesis in adrenal pheochromocytoma. 61
31106414 2019
17
A Jeffrey Fluid Model for a Porous-walled Channel: Application to Flat Plate Dialyzer. 61
31685879 2019
18
The serine protease inhibitors and SERPINE1/2 disrupt prostaglandin E2 production and hyaluronic acid retention in FSH-stimulated pig cumulus-oocyte complexes. 61
31625245 2019
19
Acute Febrile Illness Caused by Brucella abortus Infection in Humans in Pakistan. 61
31652718 2019
20
Disordered APC/C-mediated cell cycle progression and IGF1/PI3K/AKT signalling are the potential basis of Sertoli cell-only syndrome. 61
30995700 2019
21
Driving Pressure: Defining the Range. 61
31088990 2019
22
Alcohol-Induced Mesenteric Lymphatic Permeability: Link to Immunometabolic Modulation of Perilymphatic Adipose Tissue. 61
31443389 2019
23
PEEP titration in moderate to severe ARDS: plateau versus transpulmonary pressure. 61
31312921 2019
24
The Nodule-Specific PLAT Domain Protein NPD1 Is Required for Nitrogen-Fixing Symbiosis. 61
31061106 2019
25
Plasminogen activator, tissue type regulates germinal vesicle breakdown and cumulus expansion of bovine cumulus-oocyte complex in vitro†. 61
30939202 2019
26
Comparing the effect of tempe flour and tofu flour consumption on estrogen serum in ovariectomized rats. 61
31245636 2019
27
Association Analysis of Charcoal Rot Disease Resistance in Soybean. 61
31244565 2019
28
Nodule-specific PLAT domain proteins are expanded in the Medicago lineage and required for nodulation. 61
30664233 2019
29
Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study. 61
30790030 2019
30
Profiling of Alzheimer's disease related genes in mild to moderate vitamin D hypovitaminosis. 61
30889441 2019
31
Investigations on the Role of the Fibrinolytic Pathway on Outflow Facility Regulation. 61
30995314 2019
32
Laboratory Investigation on the Shrinkage Cracking of Waste Fiber-Reinforced Recycled Aggregate Concrete. 61
31013758 2019
33
Comment on 'Ambulance dispatch versus GP home visit for highly urgent out-of-hours primary care' by Plat et al. 61
30346509 2019
34
An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. 61
30504459 2019
35
Effects of Sprint-Interval and Endurance Respiratory Muscle Training Regimens. 61
30216239 2019
36
Application of alveolar recruitment strategy and positive end-expiratory pressure combined with autoflow in the one-lung ventilation during thoracic surgery in obese patients. 61
30962992 2019
37
Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture. 61
30635013 2019
38
PI-Plat: a high-resolution image-based 3D reconstruction method to estimate growth dynamics of rice inflorescence traits. 61
31889986 2019
39
CeRNA Expression Profiling Identifies KIT-Related circRNA-miRNA-mRNA Networks in Gastrointestinal Stromal Tumour. 61
31552107 2019
40
Quantitative Comparative Proteomics Reveal Biomarkers for Dengue Disease Severity. 61
31921022 2019
41
Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions. 61
31105713 2019
42
Hepatocyte gene expression and DNA methylation as ancestry-dependent mechanisms in African Americans. 61
31798965 2019
43
Transcriptomic Plasticity in the Arthropod Generalist Tetranychus urticae Upon Long-Term Acclimation to Different Host Plants. 61
30333191 2018
44
Identification and prediction of novel non-coding and coding RNA-associated competing endogenous RNA networks in colorectal cancer. 61
30581274 2018
45
Role of the tissue-type plasminogen activator -7351C > T and plasminogen activator inhibitor 1 4G/5G gene polymorphisms in central serous chorioretinopathy. 61
30442055 2018
46
Identification of hub genes and analysis of prognostic values in pancreatic ductal adenocarcinoma by integrated bioinformatics methods. 61
30173393 2018
47
In vitro study of HAX1 gene therapy by retro viral transduction as a therapeutic target in severe congenital neutropenia. 61
30698159 2018
48
Superovulation alters the expression of endometrial genes critical to tissue remodeling and placentation. 61
29959621 2018
49
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells. 61
30394400 2018
50
Structure of the human PKD1-PKD2 complex. 61
30093605 2018

Variations for Thyroid Hyalinizing Trabecular Adenoma

Expression for Thyroid Hyalinizing Trabecular Adenoma

Search GEO for disease gene expression data for Thyroid Hyalinizing Trabecular Adenoma.

Pathways for Thyroid Hyalinizing Trabecular Adenoma

GO Terms for Thyroid Hyalinizing Trabecular Adenoma

Sources for Thyroid Hyalinizing Trabecular Adenoma

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