MCID: THY031
MIFTS: 27

Thyroid Sarcoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Thyroid Sarcoma

MalaCards integrated aliases for Thyroid Sarcoma:

Name: Thyroid Sarcoma 12 15 74
Sarcoma of the Thyroid Gland 12
Thyroid Gland Sarcoma 17

Classifications:



External Ids:

Disease Ontology 12 DOID:4515
NCIt 51 C6041
UMLS 74 C1336756

Summaries for Thyroid Sarcoma

Disease Ontology : 12 A thyroid cancer that is located in the supporting cells of the thyroid.

MalaCards based summary : Thyroid Sarcoma, also known as sarcoma of the thyroid gland, is related to thyroid angiosarcoma and thyroiditis. An important gene associated with Thyroid Sarcoma is PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1), and among its related pathways/superpathways is Cell adhesion molecules (CAMs). Affiliated tissues include the supporting cells of the thyroid, thyroid and myeloid.

Related Diseases for Thyroid Sarcoma

Diseases related to Thyroid Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 thyroid angiosarcoma 31.6 CD34 TG
2 thyroiditis 29.3 CALCA TG
3 sarcoma, synovial 10.3
4 spindle cell sarcoma 10.1
5 kaposiform hemangioendothelioma 10.1 CD34 PECAM1
6 ewing sarcoma 10.1
7 erythema elevatum diutinum 10.0 CD34 PECAM1
8 exophthalmos 9.9 CD34 TG
9 cell type benign neoplasm 9.9 CD34 TG
10 kaposi sarcoma 9.9
11 osteogenic sarcoma 9.9
12 reticulum cell sarcoma 9.9
13 acute leukemia 9.9
14 leukemia 9.9
15 lymphoma 9.9
16 monophasic synovial sarcoma 9.9
17 follicular dendritic cell sarcoma 9.9
18 myeloid sarcoma 9.9
19 hemangioma 9.9 CD34 PECAM1
20 sarcoma 9.8
21 mucoepidermoid thyroid carcinoma 9.8 CALCA TG
22 suppurative thyroiditis 9.8 CALCA TG
23 atypical follicular adenoma 9.8 CALCA TG
24 follicular adenoma 9.8 CALCA TG
25 acute thyroiditis 9.8 CALCA TG
26 hypoadrenalism 9.8 CALCA TG
27 amyloid tumor 9.8 CALCA TG
28 fetal adenoma 9.8 CALCA TG
29 nontoxic goiter 9.8 CALCA TG
30 goiter 9.8 CALCA TG
31 papillary thyroid microcarcinoma 9.8 CALCA TG
32 ovarian cystic teratoma 9.8 CALCA TG
33 nodular goiter 9.8 CALCA TG
34 multinodular goiter 9.8 CALCA TG
35 thyroid gland disease 9.8 CALCA TG
36 papillary carcinoma 9.7 CALCA TG
37 mucoepidermoid carcinoma 9.7 CALCA TG
38 endocrine gland cancer 9.7 CALCA TG
39 thyroid carcinoma, familial medullary 9.7 CALCA TG
40 hashimoto thyroiditis 9.6 CALCA TG
41 thyroid cancer, nonmedullary, 2 9.6 CALCA TG
42 hypothyroidism 9.4 CALCA TG

Graphical network of the top 20 diseases related to Thyroid Sarcoma:



Diseases related to Thyroid Sarcoma

Symptoms & Phenotypes for Thyroid Sarcoma

Drugs & Therapeutics for Thyroid Sarcoma

Search Clinical Trials , NIH Clinical Center for Thyroid Sarcoma

Genetic Tests for Thyroid Sarcoma

Anatomical Context for Thyroid Sarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Thyroid Sarcoma:

20
The Supporting Cells Of The Thyroid

MalaCards organs/tissues related to Thyroid Sarcoma:

42
Thyroid, Myeloid, B Cells

Publications for Thyroid Sarcoma

Articles related to Thyroid Sarcoma:

(show all 15)
# Title Authors Year
1
Synovial Sarcoma of the Thyroid Gland, Diagnostic Pitfalls and Clinical Management. ( 30194178 )
2018
2
Mixed Phenotypic Acute Leukemia (mixed myeloid/B-cell) with Myeloid Sarcoma of the Thyroid Gland: A Rare Entity with Rarer Asssociation - Detected on FDG PET/CT. ( 28242986 )
2017
3
Primary Thyroid Sarcoma: A Systematic Review. ( 26408676 )
2015
4
Fine needle aspiration of secondary synovial sarcoma of the thyroid gland. ( 26304470 )
2015
5
Primary synovial sarcoma of the thyroid gland: case report and review of the literature. ( 24575008 )
2014
6
Extra-osseous Ewing sarcoma of the thyroid gland mimicking lymphoma recurrence: a case report. ( 22520405 )
2012
7
Extraosseous Ewing sarcoma of the thyroid gland. ( 19690849 )
2009
8
Kaposi's sarcoma of the thyroid gland in an HIV-negative woman: a case report. ( 17536546 )
2007
9
Sarcoma of the thyroid gland: a case report. ( 12193877 )
2002
10
An osteogenic sarcoma of the thyroid gland (report of a case and survey of the literature). ( 293502 )
1979
11
Sarcoma of the thyroid gland: twenty-two cases in Denmark 1943-1968. ( 949915 )
1976
12
Reticulum cell sarcoma of the thyroid gland. ( 13269637 )
1955
13
SARCOMA OF THE THYROID GLAND. ( 17866248 )
1930
14
VII. Removal of a Thyroid Sarcoma under Cocaine Anaesthesia. ( 17860445 )
1897
15
VII. Primary Sarcoma of the Thyroid Gland. ( 17860498 )
1897

Variations for Thyroid Sarcoma

Expression for Thyroid Sarcoma

Search GEO for disease gene expression data for Thyroid Sarcoma.

Pathways for Thyroid Sarcoma

Pathways related to Thyroid Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.78 CD34 PECAM1

GO Terms for Thyroid Sarcoma

Cellular components related to Thyroid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 CD34 PECAM1

Biological processes related to Thyroid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.32 CD34 PECAM1
2 regulation of blood pressure GO:0008217 9.26 CALCA CD34
3 endothelial cell migration GO:0043542 9.16 CALCA PECAM1
4 leukocyte cell-cell adhesion GO:0007159 8.96 CALCA PECAM1
5 glomerular endothelium development GO:0072011 8.62 CD34 PECAM1

Molecular functions related to Thyroid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 CALCA TG

Sources for Thyroid Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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