Aliases & Classifications for Thyroiditis

MalaCards integrated aliases for Thyroiditis:

Name: Thyroiditis 12 56 6 45 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7166
ICD9CM 36 245 245.9
MeSH 45 D013966
NCIt 51 C26894
SNOMED-CT 69 82119001
ICD10 34 E06 E06.9
UMLS 74 C0040147

Summaries for Thyroiditis

MalaCards based summary : Thyroiditis is related to thyroid carcinoma, familial medullary and familial thyroid dyshormonogenesis. An important gene associated with Thyroiditis is TG (Thyroglobulin), and among its related pathways/superpathways are Aldosterone synthesis and secretion and Allograft rejection. The drugs Selenium and Xylometazoline have been mentioned in the context of this disorder. Affiliated tissues include thyroid, t cells and pituitary, and related phenotypes are endocrine/exocrine gland and hematopoietic system

Wikipedia : 77 Thyroiditis is the inflammation of the thyroid gland. The thyroid gland is located on the front of the... more...

Related Diseases for Thyroiditis

Diseases in the Thyroiditis family:

Acute Thyroiditis Subacute Thyroiditis

Diseases related to Thyroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1758)
# Related Disease Score Top Affiliating Genes
1 thyroid carcinoma, familial medullary 34.4 CALCA RET TG
2 familial thyroid dyshormonogenesis 34.3 TG TPO
3 hypothyroidism, congenital, nongoitrous, 2 34.1 SERPINA7 TG TSHR
4 subacute thyroiditis 34.0 SERPINA7 TG TPO TSHR
5 thyroid crisis 34.0 SERPINA7 TG THRB
6 thyroid sarcoma 34.0 CALCA TG
7 suppurative thyroiditis 34.0 CALCA TG
8 hypothyroidism, thyroidal or athyroidal, with spiky hair and cleft palate 33.9 TG TPO
9 acute thyroiditis 33.9 CALCA TG
10 differentiated thyroid carcinoma 33.7 RET TG TPO TSHR
11 generalized resistance to thyroid hormone 33.6 THRB TRH TXNRD2
12 mucoepidermoid thyroid carcinoma 33.6 CALCA TG
13 thyroid cancer, nonmedullary, 2 33.6 CALCA RET TG THRB TPO TSHR
14 thyroid hormone resistance, generalized, autosomal dominant 33.6 SERPINA7 TG THRB TRH TXNRD2
15 subacute lymphocytic thyroiditis 33.6 IL2 TG TPO
16 papillary thyroid microcarcinoma 33.6 CALCA TG TSHR
17 hashimoto encephalopathy 33.4 TPO TSHR
18 thyroid cancer 33.3 CALCA RET TG THRB TPO TSHB
19 hyperthyroidism 32.9 CTLA4 SERPINA7 TG THRB TPO TRH
20 goiter, multinodular 1, with or without sertoli-leydig cell tumors 32.8 TG TPO
21 hypothyroidism, congenital, nongoitrous, 4 32.8 SERPINA7 TG TPO TRH TSHB
22 congenital hypothyroidism 32.7 SERPINA7 TG TPO TSHB TSHR
23 multiple endocrine neoplasia, type iib 32.5 CALCA RET
24 struma ovarii 32.4 RET TG TSHR
25 myxedema 32.3 CTLA4 TG TPO TSHR
26 hypothyroidism 32.2 CALCA CTLA4 RET SERPINA7 TG THRB
27 multinodular goiter 32.2 CALCA TG TPO TSHR
28 follicular adenoma 32.2 CALCA RET TG TPO TSHR
29 thyroid gland disease 32.2 CALCA RET SERPINA7 TG THRB TPO
30 endemic goiter 32.2 SERPINA7 TG TPO TSHB TSHR
31 graves disease 1 31.9 SERPINA7 TG THRB TPO TRH TSHR
32 nodular goiter 31.9 CALCA RET TG TPO TSHR
33 hyperthyroxinemia 31.8 SERPINA7 TPO TRH TSHR
34 graves' disease 31.7 CTLA4 FASLG PTPN22 SERPINA7 TG TPO
35 goiter 31.7 CALCA SERPINA7 TG THRB TPO TRH
36 celiac disease 1 31.7 CTLA4 PTPN22 TG TPO
37 hashimoto thyroiditis 31.5 CALCA CTLA4 FASLG HT PRSS3 PTPN22
38 nontoxic goiter 31.4 CALCA FASLG SERPINA7 TG TPO TSHR
39 plummer's disease 31.3 TG THRB TPO
40 athyreosis 31.2 TG TSHR
41 papillary carcinoma 31.1 CALCA RET TG TPO TSHR
42 endocrine gland cancer 30.9 CALCA RET TG
43 dyshormonogenic goiter 30.6 SERPINA7 TG
44 ovarian germ cell teratoma 30.5 RET TG
45 malignant struma ovarii 30.4 RET TG
46 neonatal thyrotoxicosis 30.3 TSHR TXNRD2
47 pernicious anemia 30.2 TG TPO
48 fetal adenoma 30.1 CALCA TG
49 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 30.0 CTLA4 PTPN22 TG TPO TSHR
50 postsurgical hypothyroidism 30.0 TG TRH TSHR

Comorbidity relations with Thyroiditis via Phenotypic Disease Network (PDN):


Hypothyroidism

Graphical network of the top 20 diseases related to Thyroiditis:



Diseases related to Thyroiditis

Symptoms & Phenotypes for Thyroiditis

MGI Mouse Phenotypes related to Thyroiditis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.02 CTLA4 FASLG IL2 PTPN22 RET TG
2 hematopoietic system MP:0005397 9.96 CTLA4 FASLG IL2 PTPN22 RET TG
3 digestive/alimentary MP:0005381 9.91 CTLA4 FASLG IL2 PTPN22 RET TG
4 homeostasis/metabolism MP:0005376 9.9 CTLA4 FASLG IL2 PTPN22 RET TG
5 immune system MP:0005387 9.61 CTLA4 FASLG IL2 PTPN22 RET TG
6 respiratory system MP:0005388 9.1 CTLA4 FASLG IL2 PTPN22 RET THRB

Drugs & Therapeutics for Thyroiditis

Drugs for Thyroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 126)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Selenium Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 7782-49-2
2
Xylometazoline Approved, Investigational Phase 4 526-36-3 5709
3
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
4
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
5 Trace Elements Phase 4,Phase 3,Phase 2,Not Applicable
6 Protective Agents Phase 4,Phase 2,Not Applicable
7 Antioxidants Phase 4,Phase 2,Not Applicable
8 Micronutrients Phase 4,Phase 3,Phase 2,Not Applicable
9 Nutrients Phase 4,Phase 3,Phase 2,Not Applicable
10 Epoetin alfa Phase 4 113427-24-0
11 Hematinics Phase 4
12 Hormones Phase 4,Phase 2,Not Applicable
13 Hormone Antagonists Phase 4,Not Applicable
14 glucocorticoids Phase 4,Not Applicable
15 Antineoplastic Agents, Hormonal Phase 4
16 Anti-Inflammatory Agents Phase 4,Phase 2,Not Applicable
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
18
Iodine Approved, Investigational Phase 3,Not Applicable 7553-56-2 807
19
Ribavirin Approved Phase 3 36791-04-5 37542
20
Pembrolizumab Approved Phase 3 1374853-91-4
21 Antiviral Agents Phase 3,Phase 1,Phase 2
22 Anti-Infective Agents Phase 3,Phase 1,Phase 2,Not Applicable
23 Immunologic Factors Phase 3,Phase 1,Phase 2,Not Applicable
24 interferons Phase 3
25 Anti-Infective Agents, Local Phase 3,Not Applicable
26 Interferon-alpha Phase 3
27 cadexomer iodine Phase 3,Not Applicable
28 Antimetabolites Phase 3
29 Interferon alpha-2 Phase 3
30 Vaccines Phase 3,Phase 2
31 Antineoplastic Agents, Immunological Phase 3,Phase 1,Phase 2
32
Aldesleukin Approved Phase 1, Phase 2 110942-02-4, 85898-30-2
33
Hydroxychloroquine Approved Phase 2,Not Applicable 118-42-3 3652
34
rituximab Approved Phase 1, Phase 2,Phase 2 174722-31-7 10201696
35
Methylprednisolone Approved, Vet_approved Phase 2,Not Applicable 83-43-2 6741
36
Prednisolone phosphate Approved, Vet_approved Phase 2,Not Applicable 302-25-0
37
Methylprednisolone hemisuccinate Approved Phase 2,Not Applicable 2921-57-5
38
Prednisolone Approved, Vet_approved Phase 2,Not Applicable 50-24-8 5755
39
Aspirin Approved, Vet_approved Phase 2 50-78-2 2244
40
Ocrelizumab Approved, Investigational Phase 2 637334-45-3
41
Talimogene laherparepvec Approved, Experimental, Investigational Phase 1, Phase 2 1187560-31-1
42
Ipilimumab Approved Phase 1, Phase 2 477202-00-9
43
Calcium Approved, Nutraceutical Phase 2 7440-70-2 271
44
Vitamin D Approved, Nutraceutical, Vet_approved Phase 2 1406-16-2
45
Ergocalciferol Approved, Nutraceutical Phase 2 50-14-6 5280793
46
Prednisolone hemisuccinate Experimental Phase 2,Not Applicable 2920-86-7
47 Anti-Retroviral Agents Phase 1, Phase 2
48 Anti-HIV Agents Phase 1, Phase 2
49 Antirheumatic Agents Phase 1, Phase 2,Phase 2,Not Applicable
50 Immunoglobulins Phase 1, Phase 2,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 77)
# Name Status NCT ID Phase Drugs
1 Selenium Supplementation in Youths With Autoimmune Thyroiditis Unknown status NCT02644707 Phase 4
2 Effect of Erythropoietin in Refractory Autoimmune Encephalitis Patients Unknown status NCT03004209 Phase 4 Erythropoietin
3 Short-term Prednisone to Treat STA Study(SPTSS) Completed NCT01837433 Phase 4 Prednisone 1 week;Prednisone 6 weeks
4 To Study the Efficacy and Safety of Renessans in Chronic HCV Patients Unknown status NCT01463592 Phase 3 Interferon Alfa-2b AND RIBAVIRIN
5 Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) Completed NCT01345240 Phase 3
6 Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587) Recruiting NCT03486873 Phase 3 Standard of Care (SOC)
7 Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT Unknown status NCT02302768 Phase 2
8 IL-2 in Refractory Autoimmune Encephalitis Unknown status NCT02714959 Phase 1, Phase 2 Proleukin
9 Low-Level Laser Therapy in Chronic Autoimmune Thyroiditis Completed NCT01129492 Phase 2
10 Evaluating the Dietary Supplement Anatabloc in Thyroid Health-ASAP (Antabloc Supplementation Autoimmune Prevention) Completed NCT01551498 Phase 2
11 Rituximab in IgG4-RD: A Phase 1-2 Trial Completed NCT01584388 Phase 1, Phase 2 Rituximab
12 Evaluate Safety & Immunogenicity of a Pandemic Influenza Vaccine (GSK1562902A) in Children Completed NCT00502593 Phase 2
13 The Role of Immunomodulatory Treatment in Success of ICSI in Patients With Autoimmune Thyroiditis Recruiting NCT03289403 Phase 2 Immunomodulatory;Thyroxine
14 Efficacy of Ocrelizumab in Autoimmune Encephalitis Recruiting NCT03835728 Phase 2 Ocrelizumab;Saline
15 IVIG and Rituximab in Antibody-associated Psychosis - SINAPPS2 Recruiting NCT03194815 Phase 2 Intravenous immunoglobulin;Placebo;Rituximab
16 Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma Active, not recruiting NCT01740297 Phase 1, Phase 2 Talimogene laherparepvec;Ipilimumab
17 A Study of Sustained-Release Liothyronine Sodium (T3) in Healthy Subjects Completed NCT01581463 Phase 1 Liothyronine, Sodium
18 The Effect of Plaquenil on Serum Inflammatory Markers and Goiter in Euthyroid Young Women With Hashimoto's Thyroiditis Unknown status NCT02126683 Not Applicable Hydroxychloroquine
19 FGF-21 Levels and RMR in Children and Adolescents With Hashimoto's Thyroiditis (THYROMETABOL) Unknown status NCT02725879
20 CXCL9 and CXCL11 Levels in Patients With Autoimmune Thyroiditis and Habitual Abortions Unknown status NCT01644318
21 DNA Methylation and Autoimmune Thyroid Diseases Unknown status NCT02491567
22 NVC Test in Order to Assess Pathological Changes in Family Members of Patient Diagnosed With SSc Unknown status NCT02795221
23 TSH And AMH in Infertile Women Unknown status NCT02710175
24 Genetic and Morphological Analysis of Thyrotoxic Periodic Paralysis Unknown status NCT02287363
25 Fetuin A in Hashimoto Thyroiditis Completed NCT01884649
26 Hashimotos Thyroiditis and Thyroid Cancer Completed NCT01428167
27 Oxidative Status in Children With Autoimmune Thyroiditis Completed NCT02318160
28 Low Level Laser Therapy for Autoimmune Thyroiditis Completed NCT02240563 Not Applicable
29 The Effect of Hydroxychloroquine Treatment in Hashimoto's Thyroiditis Completed NCT01760421 Not Applicable Hydroxychloroquine
30 Involvement of Viral Infections in the Pathogenesis of Chronic Lymphocytic Thyroiditis Completed NCT03114267
31 Selenium Treatment in Autoimmune Thyroiditis (AIT) Completed NCT00271427 Not Applicable L-Selenomethionine
32 Isolated ACTH Deficiency in Patients With Hashimoto Thyroiditis Completed NCT00552487 Not Applicable synacthen
33 Sonographic and Laboratory Evaluation of the Thyroid Gland in Patients With Systemic Sclerosis Completed NCT01270425
34 Anti-insulin-like Growth Factor-1 Receptor (IGF-1R) Antibodies in Graves' Disease and Graves' Orbitopathy Completed NCT03498417
35 Differential Diagnosis of STA-PSV in Thyrotoxicosis Completed NCT01227499
36 Selenium Supplementation in Pregnancy Completed NCT01465867 Not Applicable
37 Clinical Application of Pulse Rate-monitoring Activity Trackers in Thyrotoxicosis Completed NCT03009357
38 Cervarix Long-term Safety Surveillance Completed NCT01498627
39 Prevalence of Circulating Parvovirus Genome in Recently Diagnosed Graves' Disease: a Case-control Study Completed NCT02798965 Not Applicable
40 Association Between Hepatitis C Virus Infection and Hematologic and Thyroid Cancers Completed NCT00342641
41 Study Assessing Risk of Autoimmune Diseases in Females (9 - 25 Years) Exposed to Cervarix® in United Kingdom Completed NCT01953822
42 Autoimmune Thyroid Disease Genetic Study Completed NCT00958113
43 Thyroid in Bariatric Surgery Completed NCT03048708 Not Applicable
44 T and B Cells in Graves' Orbitopathy Completed NCT03195296
45 Antiarrythmic Drugs - Long-term Follow-up in the Modern Era Completed NCT01082055
46 Gluten-related Disorders in Familial Mediterranean Fever Patients Completed NCT03563300 Not Applicable
47 Thyroid Function Throughout Pregnancy With and Without Iodine Supplementation Completed NCT00831402 Not Applicable
48 Hashimoto - a Surgical Disease. Total Thyroidectomy Makes Antibodies Disappear and Ameliorates Symptoms Completed NCT02319538 Not Applicable
49 Thyroid Disorders in Malaysia: A Nationwide Multicentre Study Completed NCT02190214
50 Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease Completed NCT01102205

Search NIH Clinical Center for Thyroiditis

Cochrane evidence based reviews: thyroiditis

Genetic Tests for Thyroiditis

Anatomical Context for Thyroiditis

MalaCards organs/tissues related to Thyroiditis:

42
Thyroid, T Cells, Pituitary, B Cells, Kidney, Testes, Skin

Publications for Thyroiditis

Articles related to Thyroiditis:

(show top 50) (show all 4451)
# Title Authors Year
1
Isolated adrenocorticotropic hormone deficiency and thyroiditis associated with nivolumab therapy in a patient with advanced lung adenocarcinoma: a case report and review of the literature. ( 30909965 )
2019
2
Nivolumab-induced Hypophysitis, Secondary Adrenal Insufficiency and Destructive Thyroiditis in a Patient with Lung Adenocarcinoma. ( 30449786 )
2019
3
A Case of Oculocutaneous Albinism in a Patient with Hashimoto's Thyroiditis. ( 30800642 )
2019
4
The Association between Burning Mouth Syndrome and Level of Thyroid Hormones in Hashimotos Thyroiditis in Public Hospitals in Shiraz, 2016. ( 30937336 )
2019
5
Coexistence of Papillary Thyroid Cancer and Hashimoto's Thyroiditis Developing within an Ovarian Mature Cystic Teratoma. ( 31001057 )
2019
6
Autoimmune thyroiditis in patients with type 1 diabetes mellitus: A long-term follow-up study. ( 30641774 )
2019
7
The impact of autoimmune thyroiditis on skin microcirculation in children with non-complicated type 1 diabetes mellitus. ( 30611746 )
2019
8
Pediatric differentiated thyroid carcinoma: The clinicopathological features and the coexistence of Hashimoto's thyroiditis. ( 29254871 )
2019
9
Hashimoto Encephalopathy as a Complication of Autoimmune Thyroiditis. ( 30355921 )
2019
10
Thyroiditis process as a predictive factor of sternotomy in the treatment of cervico-mediastinal goiter. ( 31074402 )
2019
11
Upregulated tissue expression of T helper (Th) 17 pathogenic interleukin (IL)-23 and IL-1β in Hashimoto's thyroiditis but not in Graves' disease. ( 30814438 )
2019
12
Establishment of clinical diagnosis model of Graves' disease and Hashimoto's thyroiditis. ( 30616573 )
2019
13
Irisin levels increase after treatment in patients with newly diagnosed Hashimoto thyroiditis. ( 29777516 )
2019
14
Influence of Hashimoto Thyroiditis on the Development of Thyroid Nodules and Cancer in Children and Adolescents. ( 30820486 )
2019
15
Quantitative Assessment of Thyroid Gland Vascularization With Vascularization Index Using Color Superb Microvascular Imaging in Pediatric Patients With Hashimoto Thyroiditis. ( 30855420 )
2019
16
The Impact of Hashimoto Thyroiditis on Thyroid Nodule Cytology and Risk of Thyroid Cancer. ( 30963137 )
2019
17
The Effect of Selenomethionine on Thyroid Autoimmunity in Euthyroid Men With Hashimoto Thyroiditis and Testosterone Deficiency. ( 31106856 )
2019
18
Destructive Thyroiditis Induced by Lenvatinib in Three Patients with Hepatocellular Carcinoma. ( 30333428 )
2019
19
Transient thyroiditis after parathyroidectomy for tertiary hyperparathyroidism. ( 31012430 )
2019
20
Post-hemithyroidectomy hypothyroidism in non autoimmune thyroiditis patients: Incidence, risk factors and duration of follow up. ( 30987945 )
2019
21
Relatively high rate of postpartum thyroiditis in the Straits of Messina area. Predictivity of both postpartum thyroiditis and permanent hypothyroidism by performing, in the first trimester of gestation, thyroid ultrasonography and measurement of serum thyroperoxidase and thyroglobulin autoantibodies. ( 30555788 )
2019
22
A Case of Interstitial Lung Disease and Autoimmune Thyroiditis Associated with Ustekinumab. ( 30426134 )
2019
23
Spontaneous intracranial hypotension in Hashimoto's thyroiditis: A case report. ( 31045829 )
2019
24
Acute exacerbation of Hashimoto's thyroiditis in a patient treated with dimethyl fumarate for multiple sclerosis: A case report. ( 31027063 )
2019
25
Auto-immune Thyroiditis in an Infant Masquerading as Congenital Nephrotic Syndrome. ( 30128632 )
2019
26
Thyrotoxic periodic paralysis complicated by life-threatening acute hypercapnic respiratory failure in a Chinese male with painless thyroiditis. ( 30424987 )
2019
27
Sonographic Pattern of Subacute Thyroiditis Is HLA-Dependent. ( 30728805 )
2019
28
The Risk of Recurrence of Subacute Thyroiditis Is HLA-Dependent. ( 30832406 )
2019
29
Clinical characteristics of subacute thyroiditis is different than it used to be - current state based on 15 years own material. ( 30860680 )
2019
30
Initial treatment combined with Prunella vulgaris reduced prednisolone consumption for patients with subacute thyroiditis. ( 30906749 )
2019
31
Hepcidin and Iron Homeostasis in Patients with Subacute Thyroiditis and Healthy Subjects. ( 30936776 )
2019
32
Treatment of lidocaine on subacute thyroiditis via restraining inflammatory factor expression and inhibiting pyroptosis pathway. ( 30963625 )
2019
33
Acute suppurative thyroiditis secondary to pyriform sinus fistula. ( 30938300 )
2019
34
Impact of thyroiditis on 131I uptake during ablative therapy for differentiated thyroid cancer. ( 30965284 )
2019
35
Is there a correlation between thyroiditis and thyroid cancer? ( 31004335 )
2019
36
Decreased staging of differentiated thyroid cancer in patients with chronic lymphocytic thyroiditis. ( 29619749 )
2019
37
Thyroglobulin Antibodies are Associated with Symptom Burden in Patients with Hashimoto's Thyroiditis: A Cross-Sectional Study. ( 30332318 )
2019
38
Atorvastatin potentiates the effect of selenomethionine on thyroid autoimmunity in euthyroid women with Hashimoto's thyroiditis. ( 30354702 )
2019
39
Aspergillus thyroiditis: In an immunocompromised young adult. ( 30499196 )
2019
40
Sonographic Characteristics of Papillary Thyroid Carcinoma with Coexistent Hashimoto's Thyroiditis: Conventional Ultrasound, Acoustic Radiation Force Impulse Imaging and Contrast-Enhanced Ultrasound. ( 30528690 )
2019
41
Severe unilateral orbitopathy in a patient with Hashimoto's thyroiditis - a case report. ( 30621642 )
2019
42
Solid papillary thyroid carcinoma with Hashimoto's thyroiditis: description of a further case with challenging cytological features. ( 30659000 )
2019
43
MYMD-1, a Novel Immunometabolic Regulator, Ameliorates Autoimmune Thyroiditis via Suppression of Th1 Responses and TNF-α Release. ( 30674573 )
2019
44
Challenging diagnosis of thyroid hormone resistance initially as Hashimoto's thyroiditis. ( 30681972 )
2019
45
Effects of vitamin D supplements on frequency of CD4+ T-cell subsets in women with Hashimoto's thyroiditis: a double-blind placebo-controlled study. ( 30696977 )
2019
46
Type 1 and type 2 iodothyronine deiodinases in the thyroid gland of patients with huge goitrous Hashimoto's thyroiditis. ( 30737677 )
2019
47
Evaluation of the impact of thyroiditis development in patients receiving immunotherapy with programmed cell death-1 inhibitors. ( 30782080 )
2019
48
Differences in Chromatin Texture and Nuclear Fractal Dimension Between Hashimoto's and Lymphocytic Thyroiditis Lymphocytes. ( 30813976 )
2019
49
Dysregulated Interleukin -33/ST2 Pathway Perpetuate Chronic Inflammation in Hashimoto's Thyroiditis. ( 30819087 )
2019
50
Did Mona Lisa suffer from postpartum thyroiditis? ( 30821015 )
2019

Variations for Thyroiditis

ClinVar genetic disease variations for Thyroiditis:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 CEL NM_001807.4(CEL): c.1975G> C (p.Ala659Pro) single nucleotide variant Uncertain significance rs587780309 GRCh37 Chromosome 9, 135946855: 135946855
2 CEL NM_001807.4(CEL): c.1975G> C (p.Ala659Pro) single nucleotide variant Uncertain significance rs587780309 GRCh38 Chromosome 9, 133071468: 133071468

Expression for Thyroiditis

Search GEO for disease gene expression data for Thyroiditis.

Pathways for Thyroiditis

GO Terms for Thyroiditis

Cellular components related to Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 CALCA FASLG IL2 PRSS3 SERPINA7 TPO
2 extracellular region GO:0005576 9.23 CALCA FASLG IL2 PRSS3 SERPINA7 TG

Biological processes related to Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.63 CALCA FASLG IL2 TG TRH TSHB
2 thyroid gland development GO:0030878 9.4 TG THRB
3 regulation of regulatory T cell differentiation GO:0045589 9.32 CTLA4 IL2
4 hormone biosynthetic process GO:0042446 9.26 TG TPO
5 hormone-mediated signaling pathway GO:0009755 9.26 THRB TRH TSHB TSHR
6 cell-cell signaling GO:0007267 9.1 CALCA FASLG IL2 TRH TSHB TSHR
7 response to pain GO:0048265 9.07 RET

Molecular functions related to Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.92 CALCA TG TRH TSHB

Sources for Thyroiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
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45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
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55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
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75 UMLS via Orphanet
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