MCID: TCK001
MIFTS: 56

Tick-Borne Encephalitis

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Tick-Borne Encephalitis

MalaCards integrated aliases for Tick-Borne Encephalitis:

Name: Tick-Borne Encephalitis 12 77 54 60 15 74
Siberian Tick-Borne Encephalitis 12 74
Encephalitis, Tick-Borne 45 17
Western European Tick-Borne Encephalitis 12
Russian Spring-Summer Encephalitis 12
Encephalitis, Far Eastern Russian 74
Encephalitis, Central European 74
Central European Encephalitis 12
West-Siberian Encephalitis 12
Encephalitis Tick-Borne 56
Taiga Encephalitis 12
Far Eastern Tbe 12
Tbe 60

Characteristics:

Orphanet epidemiological data:

60
tick-borne encephalitis
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age;

Classifications:



External Ids:

Disease Ontology 12 DOID:0050175
ICD9CM 36 063.2
MeSH 45 D004675
SNOMED-CT 69 16901001
ICD10 34 A84.1
MESH via Orphanet 46 D004675
ICD10 via Orphanet 35 A84.0 A84.1 A84.8 more
UMLS via Orphanet 75 C0014061
Orphanet 60 ORPHA297

Summaries for Tick-Borne Encephalitis

Disease Ontology : 12 A viral infectious disease that results in inflammation located in brain, has material basis in Tick-borne encephalitis virus, which is transmitted by Ixodes ticks. The infection has symptom drowsiness, has symptom confusion, has symptom sensory disturbances, and has symptom paralysis.

MalaCards based summary : Tick-Borne Encephalitis, also known as siberian tick-borne encephalitis, is related to encephalitis and west nile virus, and has symptoms including paralysis, confusion and drowsiness. An important gene associated with Tick-Borne Encephalitis is SCRIB (Scribble Planar Cell Polarity Protein), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Formaldehyde and Dimenhydrinate have been mentioned in the context of this disorder. Affiliated tissues include brain, brain and testes, and related phenotype is neoplasm.

Wikipedia : 77 Tick-borne encephalitis (TBE) is a viral infectious disease involving the central nervous system. The... more...

Related Diseases for Tick-Borne Encephalitis

Diseases related to Tick-Borne Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 104)
# Related Disease Score Top Affiliating Genes
1 encephalitis 31.8 CCR5 CD209 CXCL10 SCRIB TLR3
2 west nile virus 30.7 CCR5 CD209 OAS1 TLR3
3 herpes simplex encephalitis 30.6 CXCL11 TLR3
4 japanese encephalitis 30.3 CD209 CXCL10 TLR3
5 mouth disease 30.3 IL10 OAS1 TLR3
6 viral encephalitis 30.2 CXCL10 IL10
7 multiple sclerosis 29.9 CCR5 CXCL10 CXCL11 IL10
8 yellow fever 29.7 CCR5 OAS1
9 rabies 29.7 ALB CXCL10 TLR3
10 lyme disease 10.8
11 noonan syndrome 3 10.5
12 noonan syndrome 5 10.4
13 thrombocytopenia 10.4
14 human granulocytic anaplasmosis 10.4
15 ehrlichiosis 10.4
16 meningoencephalitis 10.4
17 dengue virus 10.4
18 louping ill 10.4
19 tick infestation 10.4
20 poliomyelitis 10.4
21 herpes simplex 10.4
22 meningitis 10.4
23 neutropenia 10.3
24 kyasanur forest disease 10.3
25 tetanus 10.3
26 vaccinia 10.3
27 influenza 10.3
28 venezuelan equine encephalitis 10.3
29 orofacial granulomatosis 10.3 CCR5 IL10
30 intraocular pressure quantitative trait locus 10.2
31 arthritis 10.2
32 crimean-congo hemorrhagic fever 10.2
33 measles 10.2
34 neuropathy 10.2
35 myoclonus 10.2
36 west nile encephalitis 10.2 OAS1 OAS3
37 mucocutaneous leishmaniasis 10.2 CCR5 IL10 TLR3
38 chronic graft versus host disease 10.2 ALB IL10
39 fascioliasis 10.1 ALB IL10
40 microphthalmia with limb anomalies 10.1 OAS1 OAS3
41 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 10.1 CCR5 CD209 IL10
42 lipoid nephrosis 10.1 ALB IL10
43 myositis 10.1
44 rheumatoid arthritis 10.1
45 schizophrenia 10.1
46 disorganization, mouse, homolog of 10.1
47 alopecia 10.1
48 dengue disease 10.1
49 hepatitis 10.1
50 hepatitis b 10.1

Graphical network of the top 20 diseases related to Tick-Borne Encephalitis:



Diseases related to Tick-Borne Encephalitis

Symptoms & Phenotypes for Tick-Borne Encephalitis

Symptoms:

12
  • paralysis
  • confusion
  • drowsiness
  • sensory disturbances

MGI Mouse Phenotypes related to Tick-Borne Encephalitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.02 ALB CCR5 IL10 SCRIB TLR3

Drugs & Therapeutics for Tick-Borne Encephalitis

Drugs for Tick-Borne Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Formaldehyde Approved, Vet_approved Phase 4 50-00-0 712
2
Dimenhydrinate Approved Phase 4 523-87-5 441281
3 Vaccines Phase 4,Phase 2,Phase 3,Phase 1
4 Immunologic Factors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
5 Immunoglobulins Phase 4,Not Applicable
6 Antibodies Phase 4,Not Applicable
7 Pharmaceutical Solutions Phase 4
8 Anti-Infective Agents Phase 4,Not Applicable
9 Disinfectants Phase 4
10 Polygeline Phase 4
11 Plasma Substitutes Phase 4
12 Blood Substitutes Phase 4
13
Lactitol Investigational Phase 3 585-88-6, 585-86-4 493591
14
Doxycycline Approved, Investigational, Vet_approved ,Not Applicable 564-25-0 54671203
15
Granisetron Approved, Investigational ,Not Applicable 109889-09-0 3510
16
Ceftriaxone Approved 73384-59-5 5479530 5361919
17
Dopamine Approved 62-31-7, 51-61-6 681
18
Acyclovir Approved 59277-89-3 2022
19 Antitubercular Agents
20 Antibiotics, Antitubercular ,Not Applicable
21 Anti-Bacterial Agents ,Not Applicable
22 dipyrone ,Not Applicable
23 Antipyretics Not Applicable
24 Antiemetics Not Applicable
25 Antimalarials Not Applicable
26 Antiparasitic Agents Not Applicable
27 Antiprotozoal Agents Not Applicable
28 Dopamine Antagonists
29 Gastrointestinal Agents
30 Neurotransmitter Agents
31 Dopamine Agents
32 Autonomic Agents
33 Peripheral Nervous System Agents
34 Antiviral Agents

Interventional clinical trials:

(show all 41)
# Name Status NCT ID Phase Drugs
1 Study to Evaluate Long Term Immunogenicity up to 10 Years After the First Booster Immunization With Tick Borne Encephalitis Vaccine in Adults Who Received 1 of 3 Different Primary Vaccination Schedules Completed NCT01562444 Phase 4
2 An Extension Study to Determine the Persistence of Tick-borne Encephalitis (TBE)-Specific Antibody Responses Among Children and Adolescents Previously Immunized Against TBE Completed NCT01106482 Phase 4
3 Cervicovaginal Immune Responses to 3 Deltoid or Thigh Intramuscular (IM) TicoVac Completed NCT01710189 Phase 4 TicoVac
4 TBE Antibody Persistence and Booster Vaccination Study in Children and Adolescents (Follow-up to Study 209) Completed NCT00161967 Phase 4
5 Tick-Borne Encephalitis (TBE) Seropersistence After First Booster and Response to a Second Booster in Children, Adolescents and Young Adults (Follow-Up to Study 700401) Completed NCT00894686 Phase 4
6 Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination Completed NCT00804219 Phase 4
7 TBE Seropersistence up to 10 Years After First Booster in Adults Completed NCT01582698 Phase 4
8 TBE Antibody Persistence and Booster Vaccination Study in Adults (Follow-up to Study 223) Completed NCT00503529 Phase 4
9 Immunogenicity and Safety Study of a Rapid Immunization Schedule With FSME-IMMUN 0.5 mL in Healthy Adults Aged 16 - 65 Years Completed NCT00161954 Phase 4
10 Influence of Persistent CMV-infection on Immune Senescence Completed NCT00461695 Phase 4
11 Investigation of the Seropersistence of TBE Antibodies and the Booster Response to FSME-IMMUN 0.5 ml in Adults Aged 18 - 67 Years Completed NCT00161785 Phase 4
12 Evaluation of Long-Term Immunogenicity in Subjects Boosted With a TBE Vaccine for Adults Completed NCT00311493 Phase 4
13 Study of the Safety, Tolerability and Immune Response of TBE Vaccines Administered to Healthy Children Completed NCT00311441 Phase 4
14 Immunogenicity and Safety Study of a Third Vaccination With FSME-IMMUN 0.5 mL in Subjects Previously Vaccinated According to a Rapid Immunization Schedule (Follow-up to Study 225) Completed NCT00163540 Phase 4
15 Comparison of Vaccination Routes: Subcutaneous Versus Intramuscular Application of FSME-Immun® Completed NCT02511587 Phase 4
16 TBE Vaccination in Allergic Patients Completed NCT02511535 Phase 4
17 The Aim of This Study is to Investigate the Persistence of Antibody Response in Adults up to 15 Years After One Booster Dose of GlaxoSmithKline (GSK) Biologicals' Encepur Adults Vaccine Active, not recruiting NCT03294135 Phase 4
18 New Study - Humoral Response to Tick-borne Encephalitis Vaccine in Elderly Unknown status NCT02318069 Phase 2, Phase 3
19 Humoral Response to Tick-borne Encephalitis Vaccine in Elderly Completed NCT01361776 Phase 2, Phase 3
20 Immunogenicity, Safety and Interchangeability of Two Tbe Vaccines Administered According to a Conventional Schedule in Children Completed NCT00840801 Phase 3
21 FSME IMMUN NEW Follow-up to Study 208 in Volunteers Aged 16 to 66 Years Completed NCT00161876 Phase 3
22 Safety and Immunogenicity Study of 3 Vaccinations With TICOVAC in 2 Dosages in Healthy Children Aged Between 6 Months and 3 Years Completed NCT00161746 Phase 2, Phase 3
23 Safety Study in Volunteers From 16 to 65 Years of Age: FSME IMMUN NEW vs. ENCEPUR Completed NCT00161824 Phase 3
24 Safety Study of FSME-IMMUN NEW in Healthy Children and Adolescents Aged 1 to 15 Years Completed NCT00161863 Phase 3
25 Study to Evaluate the Efficacy, Safety and Immunogenicity of Influenza Vaccine in Healthy Subjects (Aged 6 to <72 Months) Versus Control Vaccines Completed NCT00644059 Phase 3
26 Evaluation of Immunogenicity of Different Tick Borne Encephalitis (TBE) Fast Protective Traveler Schemes With Inactivated TBE Whole Virus Vaccine Unknown status NCT00890422 Phase 2
27 Humoral and Cellular Immunity for TBE Vaccination in Allogeneic HSCT Recipients Completed NCT01991067 Phase 2
28 Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 6 to 16 Years. Completed NCT00161798 Phase 2
29 Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 1 to 6 Years. Completed NCT00161772 Phase 2
30 FSME IMMUN NEW Follow-up to Study 205 in Children Aged 6 to 16 Years Completed NCT00161889 Phase 2
31 FSME IMMUN NEW Follow-up to Study 199 in Children Aged 1 to 6 Years Completed NCT00161850 Phase 2
32 Vaccine Study for Tick-Borne Encephalitis Virus (TBEV) Terminated NCT01031537 Phase 2
33 Safety of and Immune Response to a Tick-Borne Encephalitis Vaccine (LGT(TP21)/DEN4) in Healthy Adults Completed NCT00118924 Phase 1
34 Postencephalitic Symptoms After Tick Borne Encephalitis Unknown status NCT00941590
35 Tick-borne Encephalitis and Possible Borrelial Serology Completed NCT03958058 Anti-borrelial antibiotic therapy
36 Study to Investigate the Immune Response and Safety of Prophylactic Vaccines in Patients Treated for Multiple Sclerosis Completed NCT02275741
37 Study to Investigate the Seropersistence of TBE Virus Antibodies Approx. 3 Years After a Booster Vaccination With FSME-IMMUN 0.25 mL JUNIOR in Children Completed NCT00163618
38 Tick-borne Encephalitis and Borrelial Antibodies in Serum Recruiting NCT03956446 Not Applicable Doxycycline;Symptomatic therapy
39 Tick-borne Encephalitis and Positive Borrelial Antibodies Recruiting NCT02463942 Not Applicable Doxycycline;Symptomatic therapy
40 Aseptic Meningoencephalitis in Slovenia Recruiting NCT02328469 symptomatic therapy;Ceftriaxone or Doxycycline;Acyclovir
41 Fever After Tick Bite Study Recruiting NCT03932448

Search NIH Clinical Center for Tick-Borne Encephalitis

Cochrane evidence based reviews: encephalitis, tick-borne

Genetic Tests for Tick-Borne Encephalitis

Anatomical Context for Tick-Borne Encephalitis

The Foundational Model of Anatomy Ontology organs/tissues related to Tick-Borne Encephalitis:

20
Brain

MalaCards organs/tissues related to Tick-Borne Encephalitis:

42
Brain, Testes, Kidney, T Cells, Lymph Node, B Cells, Cerebellum

Publications for Tick-Borne Encephalitis

Articles related to Tick-Borne Encephalitis:

(show top 50) (show all 1536)
# Title Authors Year
1
Serological Evidence of Tick-Borne Encephalitis and West Nile Virus Infections Among Children with Arthritis in Turkey. ( 30688547 )
2019
2
A case series of fatal meningoencephalitis in Mongolia: epidemiological and molecular characteristics of tick-borne encephalitis virus. ( 31110839 )
2019
3
Variability in the 3' untranslated regions of the genomes of the different tick-borne encephalitis virus subtypes. ( 31111398 )
2019
4
Reverse Transcription Recombinase Polymerase Amplification Assays for Rapid Detection of Tick-Borne Encephalitis Virus Infection. ( 30941699 )
2019
5
Post-exposure administration of chimeric antibody protects mice against European, Siberian, and Far-Eastern subtypes of tick-borne encephalitis virus. ( 30958863 )
2019
6
Specific detection and differentiation of tick-borne encephalitis and West Nile virus induced IgG antibodies in humans and horses. ( 30985075 )
2019
7
Model of Risk of Exposure to Lyme Borreliosis and Tick-Borne Encephalitis Virus-Infected Ticks in the Border Area of the Czech Republic (South Bohemia) and Germany (Lower Bavaria and Upper Palatinate). ( 30986900 )
2019
8
Detection of tick-borne encephalitis virus antibodies in sera of sheep and goats in Mecklenburg-Western Pomerania (north-eastern Germany). ( 31003897 )
2019
9
Stable and Highly Immunogenic MicroRNA-Targeted Single-Dose Live Attenuated Vaccine Candidate against Tick-Borne Encephalitis Constructed Using Genetic Backbone of Langat Virus. ( 31015334 )
2019
10
Preparation and Investigation of Silver Nanoparticle⁻Antibody Bioconjugates for Electrochemical Immunoassay of Tick-Borne Encephalitis. ( 31067666 )
2019
11
A method for rapid and high-yield production of the tick-borne encephalitis virus E and DIII recombinant proteins in E. coli with preservation of the antigenic properties. ( 31072731 )
2019
12
Epidemiological Characteristics and Spatial Analysis of Tick-Borne Encephalitis in Jilin Province, China. ( 31074410 )
2019
13
Recent establishment of tick-borne encephalitis foci with distinct viral lineages in the Helsinki area, Finland. ( 31084456 )
2019
14
Ixodid ticks and tick-borne encephalitis virus prevalence in the South Asian part of Russia (Republic of Tuva). ( 31103456 )
2019
15
Assessment of the tau protein concentration in patients with tick-borne encephalitis. ( 30721423 )
2019
16
Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. ( 30760569 )
2019
17
Adaptive genetic diversifications among tick-borne encephalitis virus subtypes: A genome-wide perspective. ( 30776508 )
2019
18
Implementation of preventive measures against tick-borne infections in a non-endemic area for tick-borne encephalitis-Results from a population-based survey in Lower Saxony, Germany. ( 30797728 )
2019
19
Proton magnetic resonance spectroscopy (1H-MRS) of the brain in patients with tick-borne encephalitis. ( 30808997 )
2019
20
Tick-borne encephalitis (TBE) vaccine failures: A ten-year retrospective study supporting the rationale for adding an extra priming dose in individuals from the age of 50 years. ( 30843030 )
2019
21
Intrathecal complement activation by the classical pathway in tick-borne encephalitis. ( 30850976 )
2019
22
Repeated isolation of tick-borne encephalitis virus from adult Dermacentor reticulatus ticks in an endemic area in Germany. ( 30867015 )
2019
23
Host immunogenetics in tick-borne encephalitis virus infection-The CCR5 crossroad. ( 30879988 )
2019
24
Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus. ( 30901934 )
2019
25
Compounds based on 5-(perylen-3-ylethynyl)uracil scaffold: High activity against tick-borne encephalitis virus and non-specific activity against enterovirus A. ( 30909022 )
2019
26
Anti-NMDAR encephalitis preceded by non-herpetic central nervous system infection: Systematic literature review and first case of tick-borne encephalitis triggering anti-NMDAR encephalitis. ( 30913507 )
2019
27
Epidemiology of Tick-Borne Encephalitis (TBE) in Germany, 2001⁻2018. ( 30934855 )
2019
28
Tick-Borne Encephalitis Virus Antibodies in Roe Deer, the Netherlands. ( 30666954 )
2019
29
Epidemiology and pathological mechanisms of tick-borne encephalitis. ( 30674746 )
2019
30
Tick-borne encephalitis in Europe: a brief update on epidemiology, diagnosis, prevention, and treatment. ( 30678880 )
2019
31
Reviewing estimates of the burden in disability-adjusted life years (DALYs) of tick-borne encephalitis in Slovenia. ( 30686078 )
2019
32
Phylogenetic characterization of tick-borne encephalitis virus from Bornholm, Denmark. ( 30704909 )
2019
33
Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines. ( 30710567 )
2019
34
Emergence of tick-borne encephalitis (TBE) in the Netherlands. ( 30385073 )
2019
35
A Sensitive Nano Luciferase Immune Complex Assay System for Highly Sensitive and Specific Detection of Antibodies Against Tick-Borne Encephalitis Virus. ( 30431406 )
2019
36
Perceptions of tick-borne encephalitis risk: a survey of travellers and travel clinics from Canada, Germany, Sweden and the UK. ( 30476160 )
2019
37
Report of the 20th annual meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE): ISW-TBE: 20 years of commitment and still challenges ahead. ( 30172555 )
2019
38
Self-reported vaccination coverage against tick-borne encephalitis in Slovenia. ( 30197266 )
2019
39
Cost-effectiveness of a potential anti-tick vaccine with combined protection against Lyme borreliosis and tick-borne encephalitis in Slovenia. ( 30197268 )
2019
40
Ability of inactivated vaccines based on far-eastern tick-borne encephalitis virus strains to induce humoral immune response in originally seropositive and seronegative recipients. ( 30204244 )
2019
41
Tick-borne encephalitis (TBE) in children in Europe: Epidemiology, clinical outcome and comparison of vaccination recommendations. ( 30241699 )
2019
42
Continued expansion of tick-borne pathogens: Tick-borne encephalitis virus complex and Anaplasma phagocytophilum in Denmark. ( 30245088 )
2019
43
A matrix metalloproteinase 9 (MMP9) gene single nucleotide polymorphism is associated with predisposition to tick-borne encephalitis virus-induced severe central nervous system disease. ( 29496490 )
2018
44
Can Google be used to study parasitic disease? Internet searching on tick-borne encephalitis in Germany. ( 30997896 )
2018
45
Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection. ( 31022685 )
2018
46
Effectiveness of primary vaccination against tick-borne encephalitis in employees of the armed forces. ( 30817872 )
2018
47
Milk outbreaks of tick-borne encephalitis in Slovakia, 2012-2016. ( 30817873 )
2018
48
Serostatus and risk factors of tick-borne encephalitis. ( 30817875 )
2018
49
Multinational survey shows low awareness of tick-borne encephalitis and rabies among travellers to endemic regions. ( 30561667 )
2018
50
Tick-borne encephalitis virus in cows and unpasteurized cow milk from Norway. ( 30593734 )
2018

Variations for Tick-Borne Encephalitis

Expression for Tick-Borne Encephalitis

Search GEO for disease gene expression data for Tick-Borne Encephalitis.

Pathways for Tick-Borne Encephalitis

Pathways related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.57 CCR5 CD209 CXCL10 GSN IFNL3 IL10
2
Show member pathways
12.96 CCR5 CXCL10 IFNL3 IL10 OAS1 OAS3
3 12.22 CXCL10 IL10 OAS1 TLR3
4
Show member pathways
12.04 CXCL10 CXCL11 IL10 OAS1 OAS3 TLR3
5 11.97 CCR5 GSN SCRIB
6
Show member pathways
11.67 CCR5 CXCL10 CXCL11
7
Show member pathways
11.66 CCR5 CXCL10 CXCL11 GSN TLR3
8 11.28 CXCL10 CXCL11 IL10
9 11.09 CXCL10 OAS1
10 11.04 CXCL10 CXCL11
11 10.88 CXCL10 CXCL11 IL10
12
Show member pathways
10.82 IFNL3 OAS1
13 10.82 CCR5 CXCL10 IL10

GO Terms for Tick-Borne Encephalitis

Cellular components related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 ALB CD209 CXCL10 CXCL11 GSN IFNL3
2 extracellular space GO:0005615 9.23 ALB CXCL10 CXCL11 GSN IFNL3 IL10

Biological processes related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.88 CD209 OAS1 OAS3 TLR3
2 innate immune response GO:0045087 9.88 CD209 IFNL3 OAS1 OAS3 TLR3
3 regulation of signaling receptor activity GO:0010469 9.84 CXCL10 CXCL11 IFNL3 IL10
4 cytokine-mediated signaling pathway GO:0019221 9.81 CCR5 CXCL10 IFNL3 IL10
5 inflammatory response GO:0006954 9.77 CCR5 CXCL10 CXCL11 IL10 TLR3
6 cell-cell signaling GO:0007267 9.76 CCR5 CXCL10 CXCL11
7 cellular response to lipopolysaccharide GO:0071222 9.73 CCR5 CXCL10 CXCL11 IL10
8 chemotaxis GO:0006935 9.72 CCR5 CXCL10 CXCL11
9 chemokine-mediated signaling pathway GO:0070098 9.67 CCR5 CXCL10 CXCL11
10 defense response GO:0006952 9.62 CCR5 CXCL10 CXCL11 TLR3
11 negative regulation of viral genome replication GO:0045071 9.58 IFNL3 OAS1 OAS3
12 negative regulation of mitotic cell cycle GO:0045930 9.57 IL10 SCRIB
13 positive regulation of release of sequestered calcium ion into cytosol GO:0051281 9.56 CXCL10 CXCL11
14 T cell chemotaxis GO:0010818 9.52 CXCL10 CXCL11
15 regulation of ribonuclease activity GO:0060700 9.46 OAS1 OAS3
16 response to virus GO:0009615 9.46 CXCL10 OAS1 OAS3 TLR3
17 leukocyte chemotaxis GO:0030595 9.43 CXCL10 CXCL11 IL10
18 immune response GO:0006955 9.43 CCR5 CXCL10 CXCL11 IL10 OAS1 OAS3
19 defense response to virus GO:0051607 9.02 CXCL10 IFNL3 OAS1 OAS3 TLR3

Molecular functions related to Tick-Borne Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 CXCL10 IFNL3 IL10
2 double-stranded RNA binding GO:0003725 9.33 OAS1 OAS3 TLR3
3 CXCR3 chemokine receptor binding GO:0048248 8.96 CXCL10 CXCL11
4 2'-5'-oligoadenylate synthetase activity GO:0001730 8.62 OAS1 OAS3
5 protein binding GO:0005515 10.06 ALB CCR5 CD209 CXCL10 CXCL11 GSN

Sources for Tick-Borne Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....