MCID: TCK002
MIFTS: 25

Tick Paralysis

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Tick Paralysis

MalaCards integrated aliases for Tick Paralysis:

Name: Tick Paralysis 12 73 20 44 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11285
MeSH 44 D013985
SNOMED-CT 67 74225001
UMLS 70 C0040197

Summaries for Tick Paralysis

Disease Ontology : 12 A tick infestation that is characterized by an acute, ascending, flaccid motor paralysis, which is caused by the introduction of a neurotoxin into humans during attachment and feeding by the females of several tick species such as Dermacentor andersoni, Dermacentor variabilis, Amblyomma americanum, Amblyomma maculatum, Ixodes scapularis, Ixodes pacificus, Ixodes holocyclus, Rhipicephalus sanguineus and Otobius megnini. The symptoms include local inflammation, edema and hemorrhage.

MalaCards based summary : Tick Paralysis is related to guillain-barre syndrome and ataxia and polyneuropathy, adult-onset. An important gene associated with Tick Paralysis is URB2 (URB2 Ribosome Biogenesis Homolog). Affiliated tissues include salivary gland, heart and tongue.

Wikipedia : 73 Tick paralysis is the only tick-borne disease that is not caused by an infectious organism. The illness... more...

Related Diseases for Tick Paralysis

Diseases related to Tick Paralysis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 guillain-barre syndrome 10.4
2 ataxia and polyneuropathy, adult-onset 10.3
3 foodborne botulism 10.3
4 respiratory failure 10.2
5 poliomyelitis 10.2
6 myasthenia gravis 10.0
7 kearns-sayre syndrome 10.0
8 rabies 10.0
9 facial paralysis 10.0
10 tularemia 10.0
11 tick infestation 10.0
12 neuromuscular disease 10.0
13 colorado tick fever 10.0
14 paraplegia 10.0
15 anisocoria 9.9
16 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.9
17 leprosy 3 9.9
18 rocky mountain spotted fever 9.9
19 disease by infectious agent 9.9
20 aspiration pneumonia 9.9
21 transverse myelitis 9.9
22 ehrlichiosis 9.9
23 spotted fever 9.9
24 epidural abscess 9.9
25 horner's syndrome 9.9
26 lyme disease 9.9
27 bronchopneumonia 9.9
28 pancytopenia 9.9
29 quadriplegia 9.9
30 diarrhea 9.9
31 polyneuropathy 9.9
32 myelitis 9.9
33 cellulitis 9.9
34 myocarditis 9.9
35 neuropathy 9.9
36 babesiosis 9.9
37 yellow fever 9.9
38 hansen's disease 9.9
39 anoxia 9.9
40 autonomic dysfunction 9.9
41 tremor 9.9
42 niemann-pick disease, type b 9.9 URB2 URB1
43 epididymis disease 9.5 CRISP2 CRISP1
44 orchitis 9.4 PROK2 CRISP2 CRISP1

Graphical network of the top 20 diseases related to Tick Paralysis:



Diseases related to Tick Paralysis

Symptoms & Phenotypes for Tick Paralysis

Drugs & Therapeutics for Tick Paralysis

Search Clinical Trials , NIH Clinical Center for Tick Paralysis

Cochrane evidence based reviews: tick paralysis

Genetic Tests for Tick Paralysis

Anatomical Context for Tick Paralysis

MalaCards organs/tissues related to Tick Paralysis:

40
Salivary Gland, Heart, Tongue, Skin

Publications for Tick Paralysis

Articles related to Tick Paralysis:

(show top 50) (show all 256)
# Title Authors PMID Year
1
Imaging appearance of ticks in tick paralysis. 61
33030587 2021
2
Efficacy of combination products containing sarolaner, moxidectin and pyrantel (Simparica Trio™) or afoxolaner and milbemycin (NexGard Spectra®) against induced infestations of Ixodes holocyclus in dogs. 61
32891172 2020
3
Foodborne Botulism: Clinical Diagnosis and Medical Treatment. 61
32784744 2020
4
Apparent Ixodes tick paralysis in a cat from North America. 61
33117555 2020
5
Tick paralysis in a free-ranging bobcat (Lynx rufus). 61
31961273 2020
6
Survey of cases of tick-paralysis and the presence of the eastern paralysis tick, Ixodes holocyclus, and the southern paralysis tick, Ixodes cornuatus, in the Greater Melbourne Area. 61
31670398 2020
7
Tick paralysis in dogs and cats in Australia: treatment and prevention deliverables from 100 years of research. 61
31762008 2020
8
Cardiorespiratory physiological perturbations after acute smoke-induced lung injury and during extracorporeal membrane oxygenation support in sheep. 61
32953091 2020
9
Acute Neuromuscular Disorders in the Pediatric Intensive Care Unit. 61
31502491 2020
10
Diffusion-Weighted Imaging Findings of Ischemic Spinal Injury in a Chondrodystrophic Dog With Fibrocartilaginous Embolism. 61
33363237 2020
11
Characterization and Pattern of Culling in Goats. 61
31939263 2019
12
Presumptive tick paralysis in 2 American Miniature horses in the United States. 61
31161701 2019
13
Hematology and Plasma Biochemistry of Wild Spectacled Flying Foxes ( Pteropus conspicillatus) in Australia. 61
30325258 2019
14
A Case of Tick-Borne Paralysis in a Traveling Patient. 61
31346482 2019
15
Laboratory evaluations of the 3-month efficacy of oral lotilaner (Credelio™) against experimental infestations of dogs with the Australian paralysis tick, Ixodes holocyclus. 61
30157914 2018
16
Clinical presentations, treatments and risk factors for mortality in cats with tick paralysis caused by Ixodes holocyclus: 2077 cases (2008-2016). 61
28994630 2018
17
New research makes up for lost time on feline tick paralysis. 61
29793399 2018
18
Tick Paralysis: Solving an Enigma. 61
29757990 2018
19
Are recreational areas a risk factor for tick paralysis in urban environments? 61
29657015 2018
20
What's eating you? Ixodes tick and related diseases, part 2: diagnosis and treatment of regional tick-borne diseases. 61
29763485 2018
21
What's eating you? Ixodes tick and related diseases, part 1: life cycle, local reactions, and lyme disease. 61
29718024 2018
22
[Tick Infestation of the Eyelid: Case Report and Literature Review]. 61
29596772 2018
23
What's eating you? clinical manifestations of Dermacentor tick bites. 61
29529110 2018
24
Diagnosis and Treatment of Lower Motor Neuron Disease in Australian Dogs and Cats. 61
30159335 2018
25
Tick paralysis 61
29667376 2018
26
A Retrospective Cohort Study of Tick Paralysis in British Columbia. 61
29083955 2017
27
Delineation of an endemic tick paralysis zone in southeastern Australia. 61
29080763 2017
28
Tick paralysis. 61
29084761 2017
29
The first record of infestation by a native tick (Acari: Ixodidae) on the Australian emu (Dromaius novaehollandiae) and a review of tick paralysis in Australian birds. 61
28849543 2017
30
Searching for Lyme borreliosis in Australia: results of a canine sentinel study. 61
28285585 2017
31
Comparative speed of kill of sarolaner (Simparica®) and afoxolaner (NexGard®) against induced infestations of Ixodes holocyclus on dogs. 61
28222813 2017
32
Rare Cause of Facial Palsy: Case Report of Tick Paralysis by Ixodes Holocyclus Imported by a Patient Travelling into Singapore from Australia. 61
27618477 2016
33
Bald Eagle Nestling Mortality Associated with Argas radiatus and Argas ricei Tick Infestation and Successful Management with Nest Removal in Arizona, USA. 61
27479902 2016
34
Ticks threatening lineage of Anatolian wild sheep (Ovis gmelinii anatolica) and determination of their tick-borne pathogens. 61
27692336 2016
35
TICK-BORNE INFECTIOUS DISEASES WITH REFERENCE TO EGYPT. 61
30152938 2016
36
In this issue August 2016: Preventive health care of Pony Club horses · Treatment of subclinical Streptococcus equi in Thoroughbreds · Cardiac biomarker concentrations in canine tick paralysis · Lead toxicity diagnosis in two dogs · Feline leprosy syndrome (FLS) in a cat · Skin blistering in a dog exposed to Plumbago auriculata · Postpartum anoestrus in seasonally-calving dairy farms in Victoria · Plasmodium infection in a Leadbeater's possum. 61
27461345 2016
37
NT-proBNP and cardiac troponin I concentrations in dogs with tick paralysis caused by Ixodes holocyclus. 61
27461350 2016
38
Male tick bite: A rare cause of adult tick paralysis. 61
27218120 2016
39
Electrodiagnostic Abnormalities in Tick Paralysis: A Case Report and Review of Literature. 61
27224437 2016
40
Can Subclinical Infestation by Paralyzing Dermacentor andersoni (Acari: Ixodidae) Induce Immunity to Tick Paralysis in Sheep? 61
26802171 2016
41
Use of big data in the surveillance of veterinary diseases: early detection of tick paralysis in companion animals. 61
27215214 2016
42
A survey of ticks (Acari: Ixodidae) of companion animals in Australia. 61
27160149 2016
43
A Comparative Meta-Analysis of Tick Paralysis in the United States and Australia. 61
26359765 2015
44
Arthropod-Borne Diseases: The Camper's Uninvited Guests. 61
26350321 2015
45
A Case of Subacute Ataxia in the Summertime: Tick Paralysis. 61
25794538 2015
46
The relationship between the Southern Oscillation Index, rainfall and the occurrence of canine tick paralysis, feline tick paralysis and canine parvovirus in Australia. 61
25841899 2015
47
The association between landscape and climate and reported tick paralysis cases in dogs and cats in Australia. 61
24893694 2014
48
A 60 year old Ethiopian farmer diagnosed with tick paralysis at Adera Medical Center. 61
25812288 2014
49
Neurotoxin-induced paralysis: a case of tick paralysis in a 2-year-old child. 61
24679414 2014
50
Child neurology: tick paralysis: a diagnosis not to miss. 61
24638220 2014

Variations for Tick Paralysis

Expression for Tick Paralysis

Search GEO for disease gene expression data for Tick Paralysis.

Pathways for Tick Paralysis

GO Terms for Tick Paralysis

Cellular components related to Tick Paralysis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.02 TOLLIP PROK2 CST4 CRISP2 CRISP1

Molecular functions related to Tick Paralysis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ubiquitin binding GO:0043130 8.62 VPS28 TOLLIP

Sources for Tick Paralysis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....