MCID: TNC002
MIFTS: 38

Tinea Capitis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Capitis

MalaCards integrated aliases for Tinea Capitis:

Name: Tinea Capitis 12 44 15 72
Tinea Capitis Due to Trichophyton Rubrum 12
Dermatophytosis of Scalp or Beard 12
Trichophyton Rubrum Tinea Capitis 12
Dermatophytosis of Scalp 12
Scalp Ringworm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4337
ICD9CM 35 110.0
MeSH 44 D014006
NCIt 50 C34536
UMLS 72 C0011640 C0040250

Summaries for Tinea Capitis

Disease Ontology : 12 A dermatophytosis that results in contagious fungal infection located in scalp, located in hair of head, located in eyebrow or located in eyelash, has material basis in Ascomycota fungi that belong to a group called dermatophytes and has symptom itching of the scalp, has symptom pus filled lesions on the scalp, and has symptom patches of hair loss, sometimes with a 'black dot' pattern.

MalaCards based summary : Tinea Capitis, also known as tinea capitis due to trichophyton rubrum, is related to dermatophytosis and kerion celsi, and has symptoms including itching of the scalp, pus filled lesions on the scalp and patches of hair loss. An important gene associated with Tinea Capitis is KATNAL2 (Katanin Catalytic Subunit A1 Like 2). The drugs Griseofulvin and Terbinafine have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and brain.

Wikipedia : 75 Tinea capitis (also known as "herpes tonsurans", "ringworm of the hair", "ringworm of the scalp", "scalp... more...

Related Diseases for Tinea Capitis

Diseases related to Tinea Capitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 dermatophytosis 31.4 KATNAL2 FLNC CARD9
2 kerion celsi 12.2
3 tinea favosa 11.9
4 ectothrix infectious disease 11.5
5 endothrix infectious disease 11.5
6 alopecia 11.1
7 tinea corporis 10.8
8 seborrheic dermatitis 10.7
9 alopecia areata 10.7
10 folliculitis 10.6
11 dermatomycosis 10.6
12 basal cell carcinoma 10.6
13 tinea pedis 10.5
14 cellulitis 10.5
15 skin disease 10.5
16 tinea unguium 10.5
17 dermatitis 10.5
18 thyroid carcinoma 10.5
19 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.5
20 keratosis 10.5
21 pyoderma 10.5
22 pustulosis of palm and sole 10.4
23 psoriasis 10.4
24 tinea barbae 10.4
25 skin carcinoma 10.4
26 adenoma 10.4
27 impetigo 10.4
28 lupus erythematosus 10.4
29 neurofibromatosis, type ii 10.3
30 systemic lupus erythematosus 10.3
31 meningioma, radiation-induced 10.3
32 meningioma, familial 10.3
33 superficial mycosis 10.3
34 diffuse alopecia areata 10.3
35 spinal meningioma 10.3
36 thyroid gland cancer 10.3
37 secretory meningioma 10.3
38 lymphoplasmacyte-rich meningioma 10.3
39 pemphigus 10.3
40 quinquaud's decalvans folliculitis 10.3
41 discoid lupus erythematosus 10.3
42 autoimmune disease 10.1
43 pemphigus vulgaris, familial 10.1
44 thyroid cancer, nonmedullary, 1 10.1
45 ataxia-telangiectasia 10.1
46 immune deficiency disease 10.1
47 papillon-lefevre syndrome 10.1
48 leprosy 3 10.1
49 mycosis fungoides 10.1
50 perifolliculitis capitis abscedens et suffodiens, familial 10.1

Graphical network of the top 20 diseases related to Tinea Capitis:



Diseases related to Tinea Capitis

Symptoms & Phenotypes for Tinea Capitis

Symptoms:

12
  • itching of the scalp
  • pus filled lesions on the scalp
  • patches of hair loss

Drugs & Therapeutics for Tinea Capitis

Drugs for Tinea Capitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Griseofulvin Approved, Investigational, Vet_approved Phase 3 126-07-8 441140
2
Terbinafine Approved, Investigational, Vet_approved Phase 3 91161-71-6 1549008 5402
3
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
4
Albendazole Approved, Vet_approved Phase 2, Phase 3 54965-21-8 2082
5 Papaya Approved Phase 2, Phase 3
6 Micronutrients Phase 2, Phase 3
7 14-alpha Demethylase Inhibitors Phase 3
8 Hormones Phase 3
9 Cytochrome P-450 Enzyme Inhibitors Phase 3
10 Steroid Synthesis Inhibitors Phase 3
11 Anti-Infective Agents Phase 2, Phase 3
12 Hormone Antagonists Phase 3
13 Trace Elements Phase 2, Phase 3
14 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
15 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
16 Cytochrome P-450 CYP2C19 Inhibitors Phase 3
17 Antiparasitic Agents Phase 2, Phase 3
18 Tubulin Modulators Phase 2, Phase 3
19 Anthelmintics Phase 2, Phase 3
20 Antiprotozoal Agents Phase 2, Phase 3
21 Antimitotic Agents Phase 2, Phase 3
22
Ciclopirox Approved, Investigational 29342-05-0 2749
23
Selenium Approved, Investigational, Vet_approved 7782-49-2
24
Ketoconazole Approved, Investigational 65277-42-1 47576
25 Cytochrome P-450 CYP3A Inhibitors
26 Selenium disulfide
27 Antioxidants
28 Protective Agents
29 Dermatologic Agents
30 Nutrients

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment Completed NCT02464826 Phase 4 Nailprotex
2 Efficacy and Safety of Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117754 Phase 3 Terbinafine hydrochloride
3 An Open Label, Multicenter Trial Of Diflucan (Fluconazole) For 6 Weeks Given Once Daily To Pediatric Patients With Tinea Capitis Completed NCT00645242 Phase 3 fluconazole
4 Efficacy and Safety of Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117767 Phase 3 Terbinafine hydrochloride (HCl);Griseofulvin
5 Design and Clinical Evaluation of a School Meal With Deworming Properties Completed NCT02725255 Phase 2, Phase 3 Albendazole
6 Evaluation of Preclinical Toxicity of a Siddha Formulation Kandhaga Rasayanam ( KR ) and Its Therapeutic Efficacy in Padarthamarai ( Dermatophytoses ) by an Open Clinical Trial Completed NCT02238912 Phase 2 kandhaga rasayanam
7 A Double-Blind, Randomized, Vehicle-Control, Multicenter Study to Evaluate the Efficacy and Safety of NAFT900 in Children With Tinea Capitis Aged 6 to < 13 Years Withdrawn NCT02658292 Phase 2 Naftifine hydrochloride foam, 3%;Vehicle
8 Relevance of Trichoscopy in Differential Diagnosis of Focal Non-cicatricial Alopecia in Children Unknown status NCT03260777
9 A Randomized, Double-Blinded, Placebo-Controlled Study Observing the Efficacy of Selenium Sulfide 1% Shampoo, Ketoconazole 2% Shampoo, and Ciclopirox 1% Shampoo as Adjunctive Treatments for Tinea Capitis in Children Completed NCT00127868 oral griseofulvin, selenium sulfide shampoo 1%, ciclopirox shampoo , ketoconazole shampoo 2%, baby shampoo
10 Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis. Prospective, Multicenter Study (ETDT) Completed NCT02550496
11 The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation Completed NCT00224926
12 Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation Completed NCT00590421
13 The Role of Trichoscopy in the Preliminary Diagnosis of Immunobollous Diseases Not yet recruiting NCT03478072

Search NIH Clinical Center for Tinea Capitis

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Clioquinol
Griseofulvin
Griseofulvin
Griseofulvin ultramicrosize
terbinafine
Terbinafine
Terbinafine hydrochloride

Cochrane evidence based reviews: tinea capitis

Genetic Tests for Tinea Capitis

Anatomical Context for Tinea Capitis

MalaCards organs/tissues related to Tinea Capitis:

41
Skin, Thyroid, Brain, Testes, Pituitary, Colon, Cervix

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Capitis:

19
Scalp, Hair Of Head, Eyebrow, Eyelash

Publications for Tinea Capitis

Articles related to Tinea Capitis:

(show top 50) (show all 1648)
# Title Authors PMID Year
1
Estimated Burden of Fungal Infections in Namibia. 38
31426392 2019
2
[Tinea capitis-diagnostic measures in an outbreak situation : Case report and review of the literature]. 38
31098691 2019
3
Pediatric tinea capitis caused by Trichophyton violaceum and Trichophyton soudanense in Rochester, Minnesota, United States. 38
30548845 2019
4
Griseofulvin vs terbinafine for paediatric tinea capitis: When and for how long. 38
31343780 2019
5
Trichoscopic signs of tinea capitis: association with dermatophyte or hair type? 38
31361332 2019
6
One-Step Triple-Layer Reconstruction of an Exposed Calvarium in a Radiated Tinea Capitis Patient. 38
31348200 2019
7
Tinea capitis in adults: A 18-year retrospective, single-centre study in Korea. 38
30980768 2019
8
Reflectance confocal microscopy of tinea capitis: comparing images with results of dermoscopy and mycological exams. 38
30229878 2019
9
Dermatophytic mycetoma of the scalp due to an atypical strain of Microsporum audouinii identified by MALDI-TOF MS and ITS sequencing. 38
30956063 2019
10
Molecular diagnosis of kerion celsi caused by Trichophyton tonsurans in a Italian child. 38
31080711 2019
11
The first case report of kerion-type scalp mycosis caused by Aspergillus protuberus. 38
31182059 2019
12
Epidemiology of dermatophytosis in northeastern Iran; A subtropical region. 38
31321333 2019
13
Estimated Burden of Serious Fungal Infections in Ghana. 38
31083531 2019
14
Folliculotropic mycosis fungoides in a pediatric patient mimicking black dot tinea capitis. 38
30791127 2019
15
Scalp BCC's and meningioma following X-ray epilation for tinea capitis. 38
30378096 2019
16
Epidemiology of dermatophytic infections between 2008 and 2017 in Barcelona, Spain. 38
31076176 2019
17
Molecular epidemiology and in vitro antifungal susceptibility of Trichophyton schoenleinii, agent of tinea capitis favosa. 38
30597639 2019
18
Molecular characterization and antifungal susceptibility profile of dermatophytes isolated from scalp dermatophyte carriage in primary school children in Arak city, Center of Iran. 38
30660447 2019
19
An Undetected Case of Tinea Capitis in an Elderly Woman Affected by Dermatomyositis: How Trichoscopy Can Guide to the Right Diagnosis. 38
31049345 2019
20
Extensive tinea capitis and corporis in a child caused by Trichophyton verrucosum. 38
30799183 2019
21
A single typical trichoscopic feature is predictive of tinea capitis: a prospective multicentre study. 38
30844082 2019
22
Clinico-mycological profile of tinea capitis and its comparative response to griseofulvin versus terbinafine. 38
31049453 2019
23
Infectious skin disorders encountered in a pediatric emergency department of a tertiary care hospital in Argentina: a descriptive study. 38
30246865 2019
24
Utility of trichoscopy in tinea capitis. 38
30425136 2019
25
[Epidemiological, clinical and etiological profile of tinea capitis in adult patients in Dakar, Senegal]. 38
30638814 2019
26
A case report of tinea capitis in infant in first year of life. 38
30795738 2019
27
Trichophyton violaceum: An Emerging Pathogen in Southern Switzerland. 38
31295740 2019
28
Prevalence of Tinea Capitis among Children in Osogbo, Nigeria, and the Associated Risk Factors. 38
30691234 2019
29
Estimated burden of serious human fungal diseases in Turkey. 38
30107069 2019
30
Dermatophytosis caused by Nannizzia nana in two siblings. 38
30691951 2019
31
Fortification of Carica papaya fruit seeds to school meal snacks may aid Africa mass deworming programs: a preliminary survey. 38
30526582 2018
32
Epidemiological and clinical aspects of dermatophytoses in Eastern Slovakia: a retrospective three-year study. 38
30817878 2018
33
A prospective study of tinea capitis in children: making the diagnosis easier with a dermoscope. 38
30591075 2018
34
Tinea capitis in children: a systematic review of management. 38
29797669 2018
35
Morse code-like hairs in tinea capitis disappear after successful treatment. 38
30264392 2018
36
Trichoscopy helps to predict the time point of clinical cure of tinea capitis. 38
29767838 2018
37
Trichoscopic features of tinea capitis in a straight-haired Hispanic woman. 38
30695983 2018
38
Three Skulls Dating from the French Revolutionary Years Diagnosed with Tinea Capitis: A Paleopathologic Approach. 38
30169450 2018
39
Common causes of paediatric alopecia 38
31195774 2018
40
Skin Infections. 38
30115333 2018
41
[Tinea capitis and onychomycosis due to Trichophyton soudanense : Successful treatment with fluconazole-literature review]. 38
29589043 2018
42
Therapy of Skin, Hair and Nail Fungal Infections. 38
30127244 2018
43
Magnitude and Associated Risk Factors of Superficial Skin Fungal Infection Among Primary School Children in Southern Tanzania. 38
30245947 2018
44
Basal cell carcinoma induced by therapeutic radiation for tinea capitis-clinicopathological study. 38
29464746 2018
45
Special Issue "Fungal Burden in Different Countries". 38
29970860 2018
46
Tinea folliculorum complicating tinea of the glabrous skin: an important yet neglected entity. 38
29087496 2018
47
Clinical Significance of Trichoscopy in Common Causes of Hair Loss in Children: Analysis of 134 Cases. 38
30386074 2018
48
A study of skin disease spectrum occurring in Angola phototype V-VI population in Luanda. 38
29573271 2018
49
Estimated Burden of Serious Fungal Diseases in Serbia. 38
29941824 2018
50
Estimated Burden of Serious Fungal Infections in Mozambique. 38
29937480 2018

Variations for Tinea Capitis

Expression for Tinea Capitis

Search GEO for disease gene expression data for Tinea Capitis.

Pathways for Tinea Capitis

GO Terms for Tinea Capitis

Sources for Tinea Capitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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