MCID: TNC002
MIFTS: 38

Tinea Capitis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Capitis

MalaCards integrated aliases for Tinea Capitis:

Name: Tinea Capitis 12 43 15 71
Tinea Capitis Due to Trichophyton Rubrum 12
Dermatophytosis of Scalp or Beard 12
Trichophyton Rubrum Tinea Capitis 12
Dermatophytosis of Scalp 12
Scalp Ringworm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4337
ICD9CM 34 110.0
MeSH 43 D014006
NCIt 49 C34536
UMLS 71 C0011640 C0040250

Summaries for Tinea Capitis

Disease Ontology : 12 A dermatophytosis that results in contagious fungal infection located in scalp, located in hair of head, located in eyebrow or located in eyelash, has material basis in Ascomycota fungi that belong to a group called dermatophytes and has symptom itching of the scalp, has symptom pus filled lesions on the scalp, and has symptom patches of hair loss, sometimes with a 'black dot' pattern.

MalaCards based summary : Tinea Capitis, also known as tinea capitis due to trichophyton rubrum, is related to dermatophytosis and tinea barbae, and has symptoms including itching of the scalp, pus filled lesions on the scalp and patches of hair loss. An important gene associated with Tinea Capitis is BLOC1S1 (Biogenesis Of Lysosomal Organelles Complex 1 Subunit 1). The drugs Griseofulvin and Terbinafine have been mentioned in the context of this disorder. Affiliated tissues include scalp, hair of head and eyebrow.

Wikipedia : 74 Tinea capitis (also known as "herpes tonsurans", "ringworm of the hair", "ringworm of the scalp", "scalp... more...

Related Diseases for Tinea Capitis

Diseases related to Tinea Capitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 dermatophytosis 31.0 SQLE SLC7A1 FLNC ELOA3B CBSL CARD9
2 tinea barbae 31.0 MBTPS2 B4GALNT2
3 dermatomycosis 31.0 CBSL B4GALNT2
4 tinea pedis 30.8 SQLE CARD9 B4GALNT2
5 folliculitis 30.6 MBTPS2 LPP
6 tinea corporis 30.6 SQLE CBSL CARD9 B4GALNT2
7 superficial mycosis 30.3 CBSL B4GALNT2
8 tinea unguium 30.2 SQLE CBSL CARD9 B4GALNT2
9 otomycosis 30.1 FLNC CBSL B4GALNT2
10 pityriasis versicolor 30.0 SQLE CBSL
11 tinea cruris 29.6 SQLE CBSL CARD9 B4GALNT2
12 meningioma, familial 28.9 SLC7A1 PTCH1 ELOA3B ELOA3 ELOA2
13 tinea imbricata 12.1
14 tinea favosa 11.9
15 ectothrix infectious disease 11.5
16 endothrix infectious disease 11.5
17 alopecia 11.1
18 seborrheic dermatitis 10.7
19 alopecia areata 10.7
20 basal cell carcinoma 10.6
21 skin disease 10.6
22 cellulitis 10.5
23 dermatitis 10.5
24 thyroid carcinoma 10.5
25 keratosis 10.5
26 pyoderma 10.5
27 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.4
28 pustulosis of palm and sole 10.4
29 psoriasis 10.4
30 skin carcinoma 10.4
31 adenoma 10.4
32 impetigo 10.4
33 lupus erythematosus 10.4
34 esophageal candidiasis 10.3 FLNC CARD9
35 telogen effluvium 10.3 SLITRK1 LPP
36 neurofibromatosis, type ii 10.3
37 systemic lupus erythematosus 10.3
38 meningioma, radiation-induced 10.3
39 diffuse alopecia areata 10.3
40 spinal meningioma 10.3
41 thyroid gland cancer 10.3
42 secretory meningioma 10.3
43 lymphoplasmacyte-rich meningioma 10.3
44 herpes zoster 10.3
45 pemphigus 10.3
46 quinquaud's decalvans folliculitis 10.3
47 discoid lupus erythematosus 10.3
48 cutaneous candidiasis 10.2 CARD9 B4GALNT2
49 mucormycosis 10.1 FLNC CARD9 B4GALNT2
50 opportunistic mycosis 10.1 FLNC CARD9 B4GALNT2

Graphical network of the top 20 diseases related to Tinea Capitis:



Diseases related to Tinea Capitis

Symptoms & Phenotypes for Tinea Capitis

Symptoms:

12
  • itching of the scalp
  • pus filled lesions on the scalp
  • patches of hair loss

Drugs & Therapeutics for Tinea Capitis

Drugs for Tinea Capitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Griseofulvin Approved, Investigational, Vet_approved Phase 3 126-07-8 441140
2
Terbinafine Approved, Investigational, Vet_approved Phase 3 91161-71-6 5402 1549008
3
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
4
Albendazole Approved, Vet_approved Phase 2, Phase 3 54965-21-8 2082
5 Papaya Approved Phase 2, Phase 3
6 Micronutrients Phase 2, Phase 3
7 Trace Elements Phase 2, Phase 3
8 Cytochrome P-450 Enzyme Inhibitors Phase 3
9 Anti-Infective Agents Phase 2, Phase 3
10 Hormone Antagonists Phase 3
11 Steroid Synthesis Inhibitors Phase 3
12 Hormones Phase 3
13 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
14 Antiparasitic Agents Phase 2, Phase 3
15 Antimitotic Agents Phase 2, Phase 3
16 Antiprotozoal Agents Phase 2, Phase 3
17 Anthelmintics Phase 2, Phase 3
18
Selenium Approved, Investigational, Vet_approved 7782-49-2
19
Ketoconazole Approved, Investigational 65277-42-1 47576
20
Ciclopirox Approved, Investigational 29342-05-0 2749
21 Strawberry Approved
22 Cytochrome P-450 CYP3A Inhibitors
23 Selenium disulfide
24 Antioxidants
25 Dermatologic Agents
26 Protective Agents
27 Nutrients
28 Acidophilus

Interventional clinical trials:

(show all 14)
# Name Status NCT ID Phase Drugs
1 A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment Completed NCT02464826 Phase 4 Nailprotex
2 Efficacy and Safety of Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117754 Phase 3 Terbinafine hydrochloride
3 An Open Label, Multicenter Trial Of Diflucan (Fluconazole) For 6 Weeks Given Once Daily To Pediatric Patients With Tinea Capitis Completed NCT00645242 Phase 3 fluconazole
4 Efficacy and Safety of Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117767 Phase 3 Terbinafine hydrochloride (HCl);Griseofulvin
5 Design and Clinical Evaluation of a School Meal With Deworming Properties Completed NCT02725255 Phase 2, Phase 3 Albendazole
6 Evaluation of Preclinical Toxicity of a Siddha Formulation Kandhaga Rasayanam ( KR ) and Its Therapeutic Efficacy in Padarthamarai ( Dermatophytoses ) by an Open Clinical Trial Completed NCT02238912 Phase 2 kandhaga rasayanam
7 A Double-Blind, Randomized, Vehicle-Control, Multicenter Study to Evaluate the Efficacy and Safety of NAFT900 in Children With Tinea Capitis Aged 6 to < 13 Years Withdrawn NCT02658292 Phase 2 Naftifine hydrochloride foam, 3%;Vehicle
8 Relevance of Trichoscopy in Differential Diagnosis of Focal Non-cicatricial Alopecia in Children Unknown status NCT03260777
9 A Randomized, Double-Blinded, Placebo-Controlled Study Observing the Efficacy of Selenium Sulfide 1% Shampoo, Ketoconazole 2% Shampoo, and Ciclopirox 1% Shampoo as Adjunctive Treatments for Tinea Capitis in Children Completed NCT00127868 oral griseofulvin, selenium sulfide shampoo 1%, ciclopirox shampoo , ketoconazole shampoo 2%, baby shampoo
10 Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis. Prospective, Multicenter Study (ETDT) Completed NCT02550496
11 The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation Completed NCT00224926
12 Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation Completed NCT00590421
13 A Nutritional Trial on Effect of Probiotic Yoghurt Containing Lactobacillus Rhamnosus Yoba on Respiratory Tract Infection and Other Health Outcomes Among Children Aged 3-6 Years in Southwest Uganda Active, not recruiting NCT04144491
14 The Role of Trichoscopy in the Preliminary Diagnosis of Immunobollous Diseases Not yet recruiting NCT03478072

Search NIH Clinical Center for Tinea Capitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Griseofulvin
Griseofulvin ultramicrosize
terbinafine
Terbinafine hydrochloride

Cochrane evidence based reviews: tinea capitis

Genetic Tests for Tinea Capitis

Anatomical Context for Tinea Capitis

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Capitis:

19
Scalp, Hair Of Head, Eyebrow, Eyelash

MalaCards organs/tissues related to Tinea Capitis:

40
Skin, Thyroid, Brain, Pituitary, Testes, Colon, Cervix

Publications for Tinea Capitis

Articles related to Tinea Capitis:

(show top 50) (show all 1678)
# Title Authors PMID Year
1
Skin Infections and Outpatient Burn Management: Fungal and Viral Skin Infections. 61
31995350 2020
2
S1 guidelines: Tinea capitis. 61
32026639 2020
3
Trichoscopy of Tinea Capitis: A Systematic Review. 61
31907867 2020
4
Retrospective two-centre study on prepubertal children with Tinea capitis in Korea. 61
31596519 2020
5
Tinea Capitis: An Updated Review. 61
31906842 2020
6
Adult black dot tinea capitis caused by Trichophyton tonsurans complicated with herpes zoster. 61
31923110 2020
7
Efficacies and merits of the Cotton Swab technique to diagnose Tinea Capitis in the Pediatric Population. 61
31940462 2020
8
Cancer incidence after childhood irradiation for tinea capitis in a Portuguese cohort. 61
31674803 2020
9
Tinea capitis: A single-institution retrospective review from 2010 to 2015. 61
31957924 2020
10
Molecular identification of isolates of the Trichophyton mentagrophytes complex. 61
31929737 2020
11
Echoes from the past- changing associations between brain tumors and ethnicity. 61
31756667 2020
12
FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis. 61
31573050 2019
13
Epidemiology of dermatophytic infections between 2008 and 2017 in Barcelona, Spain. 61
31076176 2019
14
Adult black dot tinea capitis caused by Trichophyton tonsurans complicated with herpes zoster. 61
31855965 2019
15
Tinea Capitis in Campania: A 5-Year Retrospective Study in Childhood and Adolescence (2013-2018). 61
31799263 2019
16
One-Step Triple-Layer Reconstruction of an Exposed Calvarium in a Patient With Radiated Tinea Capitis. 61
31348200 2019
17
Trichoscopic signs of tinea capitis: association with dermatophyte or hair type? 61
31361332 2019
18
A single typical trichoscopic feature is predictive of tinea capitis: a prospective multicentre study. 61
30844082 2019
19
Inflammatory Tinea Capitis Mimicking Erosive Pustulosis of the Scalp. 61
31703188 2019
20
Adult tinea capitis and tinea barbae in a tertiary Portuguese hospital: A 11-year audit. 61
31441119 2019
21
The Burden of Fungal Infections in Ethiopia. 61
31771096 2019
22
Tinea Capitis: Correlation of Clinical Aspects, Findings on Direct Mycological Examination, and Agents Isolated from Fungal Culture. 61
32030056 2019
23
The prevalence of scabies, pyoderma and other communicable dermatoses in the Bijagos Archipelago, Guinea-Bissau. 61
31738757 2019
24
First report of tinea corporis caused by Arthroderma benhamiae in Brazil. 61
31463867 2019
25
Superficial fungal infections. 61
31569324 2019
26
Epidemiology of dermatomycoses in southwest Poland, years 2011-2016. 61
31839778 2019
27
The importance of reflectance confocal microscopy for the diagnosis and the follow-up of tinea capitis. 61
31638354 2019
28
Combined and dynamic trichoscopic signs for diagnosis and follow-up of inflammatory tinea capitis. 61
31573672 2019
29
Griseofulvin vs terbinafine for paediatric tinea capitis: When and for how long. 61
31343780 2019
30
Can Dermoscopy Serve as a Diagnostic Tool in Dermatophytosis? A Pilot Study. 61
31544071 2019
31
Whole-genome resequencing of Trichophyton rubrum provides insights into population differentiation and drug resistance. 61
31538279 2019
32
Estimated Burden of Fungal Infections in Namibia. 61
31426392 2019
33
Pediatric tinea capitis caused by Trichophyton violaceum and Trichophyton soudanense in Rochester, Minnesota, United States. 61
30548845 2019
34
[Tinea capitis-diagnostic measures in an outbreak situation : Case report and review of the literature]. 61
31098691 2019
35
Reflectance confocal microscopy of tinea capitis: comparing images with results of dermoscopy and mycological exams. 61
30229878 2019
36
Tinea capitis in adults: A 18-year retrospective, single-centre study in Korea. 61
30980768 2019
37
A Clinico-Epidemiological Study of Scalp Hair Loss in Children (0-18 Years) in Kota Region, South-East Rajasthan. 61
31516137 2019
38
Telephone Handle Hair: A Novel Trichoscopic Finding in Black Dot Tinea Capitis. 61
31523114 2019
39
Dermatophytic mycetoma of the scalp due to an atypical strain of Microsporum audouinii identified by MALDI-TOF MS and ITS sequencing. 61
30956063 2019
40
The first case report of kerion-type scalp mycosis caused by Aspergillus protuberus. 61
31182059 2019
41
Molecular diagnosis of kerion celsi caused by Trichophyton tonsurans in a Italian child. 61
31080711 2019
42
Epidemiology of dermatophytosis in northeastern Iran; A subtropical region. 61
31321333 2019
43
Folliculotropic mycosis fungoides in a pediatric patient mimicking black dot tinea capitis. 61
30791127 2019
44
Estimated Burden of Serious Fungal Infections in Ghana. 61
31083531 2019
45
Scalp BCC's and meningioma following X-ray epilation for tinea capitis. 61
30378096 2019
46
Molecular epidemiology and in vitro antifungal susceptibility of Trichophyton schoenleinii, agent of tinea capitis favosa. 61
30597639 2019
47
Molecular characterization and antifungal susceptibility profile of dermatophytes isolated from scalp dermatophyte carriage in primary school children in Arak city, Center of Iran. 61
30660447 2019
48
An Undetected Case of Tinea Capitis in an Elderly Woman Affected by Dermatomyositis: How Trichoscopy Can Guide to the Right Diagnosis. 61
31049345 2019
49
Extensive tinea capitis and corporis in a child caused by Trichophyton verrucosum. 61
30799183 2019
50
Clinico-mycological profile of tinea capitis and its comparative response to griseofulvin versus terbinafine. 61
31049453 2019

Variations for Tinea Capitis

Expression for Tinea Capitis

Search GEO for disease gene expression data for Tinea Capitis.

Pathways for Tinea Capitis

GO Terms for Tinea Capitis

Cellular components related to Tinea Capitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 elongin complex GO:0070449 8.8 ELOA3B ELOA3 ELOA2

Biological processes related to Tinea Capitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cholesterol biosynthetic process GO:0045540 8.62 SQLE MBTPS2

Sources for Tinea Capitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....