MCID: TNC002
MIFTS: 41

Tinea Capitis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Capitis

MalaCards integrated aliases for Tinea Capitis:

Name: Tinea Capitis 12 45 15 74
Tinea Capitis Due to Trichophyton Rubrum 12
Dermatophytosis of Scalp or Beard 12
Trichophyton Rubrum Tinea Capitis 12
Dermatophytosis of Scalp 12
Scalp Ringworm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4337
ICD9CM 36 110.0
MeSH 45 D014006
NCIt 51 C34536

Summaries for Tinea Capitis

Disease Ontology : 12 A dermatophytosis that results in contagious fungal infection located in scalp, located in hair of head, located in eyebrow or located in eyelash, has material basis in Ascomycota fungi that belong to a group called dermatophytes and has symptom itching of the scalp, has symptom pus filled lesions on the scalp, and has symptom patches of hair loss, sometimes with a 'black dot' pattern.

MalaCards based summary : Tinea Capitis, also known as tinea capitis due to trichophyton rubrum, is related to dermatophytosis and kerion celsi, and has symptoms including itching of the scalp, pus filled lesions on the scalp and patches of hair loss. An important gene associated with Tinea Capitis is KATNAL2 (Katanin Catalytic Subunit A1 Like 2). The drugs Terbinafine and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and brain.

Wikipedia : 77 Tinea capitis (also known as "herpes tonsurans", "ringworm of the hair", "ringworm of the scalp", "scalp... more...

Related Diseases for Tinea Capitis

Diseases related to Tinea Capitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 dermatophytosis 31.7 CARD9 KATNAL2
2 kerion celsi 12.0
3 tinea favosa 11.7
4 ectothrix infectious disease 11.4
5 endothrix infectious disease 11.4
6 alopecia 10.7
7 cellulitis 10.5
8 alopecia areata 10.5
9 tinea corporis 10.5
10 basal cell carcinoma 1 10.4
11 basal cell carcinoma 10.4
12 tinea pedis 10.3
13 dermatitis 10.3
14 folliculitis 10.3
15 seborrheic dermatitis 10.3
16 lupus erythematosus 10.3
17 systemic lupus erythematosus 10.2
18 tinea barbae 10.2
19 neurofibromatosis, type ii 10.1
20 pemphigus vulgaris, familial 10.1
21 papillon-lefevre syndrome 10.1
22 mycosis fungoides 10.1
23 perifolliculitis capitis abscedens et suffodiens, familial 10.1
24 meningioma, familial 10.1
25 trichotillomania 10.1
26 central centrifugal cicatricial alopecia 10.1
27 pemphigus vulgaris 10.1
28 lymphoma 10.1
29 diffuse alopecia areata 10.1
30 dermatomyositis 10.1
31 african histoplasmosis 10.1
32 spinal meningioma 10.1
33 tinea unguium 10.1
34 histoplasmosis 10.1
35 squamous cell carcinoma 10.1
36 thyroid cancer 10.1
37 melanoma 10.1
38 skin carcinoma 10.1
39 toxic encephalopathy 10.1
40 erythrasma 10.1
41 syphilis 10.1
42 pyoderma 10.1
43 secretory meningioma 10.1
44 human immunodeficiency virus infectious disease 10.1
45 acquired immunodeficiency syndrome 10.1
46 impetigo 10.1
47 pityriasis versicolor 10.1
48 pemphigus 10.1
49 basal cell carcinoma, multiple 10.1
50 mycetoma 10.1

Graphical network of the top 20 diseases related to Tinea Capitis:



Diseases related to Tinea Capitis

Symptoms & Phenotypes for Tinea Capitis

Symptoms:

12
  • itching of the scalp
  • pus filled lesions on the scalp
  • patches of hair loss

Drugs & Therapeutics for Tinea Capitis

Drugs for Tinea Capitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Terbinafine Approved, Investigational, Vet_approved Phase 3 91161-71-6 1549008 5402
2
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 22916-47-8 4189
3
Griseofulvin Approved, Investigational, Vet_approved Phase 3,Not Applicable 126-07-8 441140
4
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
5 Papaya Approved Phase 2, Phase 3
6
Albendazole Approved, Vet_approved Phase 2, Phase 3 54965-21-8 2082
7 Antifungal Agents Phase 3,Phase 2,Not Applicable
8 Anti-Infective Agents Phase 3,Phase 2,Not Applicable
9 Steroid Synthesis Inhibitors Phase 3,Not Applicable
10 Hormone Antagonists Phase 3,Not Applicable
11 Cytochrome P-450 Enzyme Inhibitors Phase 3,Not Applicable
12 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Not Applicable
14 Cytochrome P-450 CYP2C19 Inhibitors Phase 3
15 Hormones Phase 3,Not Applicable
16 Trace Elements Phase 2, Phase 3,Not Applicable
17 Micronutrients Phase 2, Phase 3,Not Applicable
18 Antimitotic Agents Phase 2, Phase 3
19 Antiprotozoal Agents Phase 2, Phase 3
20 Antiparasitic Agents Phase 2, Phase 3
21 Anthelmintics Phase 2, Phase 3
22
Selenium Approved, Investigational, Vet_approved Not Applicable 7782-49-2
23
Ketoconazole Approved, Investigational Not Applicable 65277-42-1 47576
24
Ciclopirox Approved, Investigational Not Applicable 29342-05-0 2749
25 Nutrients Not Applicable
26 Antioxidants Not Applicable
27 Dermatologic Agents Not Applicable
28 Cytochrome P-450 CYP3A Inhibitors Not Applicable
29 Protective Agents Not Applicable
30 Selenium disulfide Not Applicable

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117767 Phase 3 Terbinafine hydrochloride (HCl);Griseofulvin
2 Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117754 Phase 3 Terbinafine hydrochloride
3 A Study Of Diflucan In Children With Ringworm Of The Scalp Completed NCT00645242 Phase 3 fluconazole
4 Design and Clinical Evaluation of a School Meal With Deworming Properties Completed NCT02725255 Phase 2, Phase 3 Albendazole
5 Evaluation of Preclinical Toxicity andTherapeutic Efficacy of Kandhaga Rasayanam in Padarthamarai Completed NCT02238912 Phase 2 kandhaga rasayanam
6 Safety and Efficacy of NAFT900 in Children With Tinea Capitis Withdrawn NCT02658292 Phase 2 Naftifine hydrochloride foam, 3%;Vehicle
7 Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis Completed NCT02550496 Not Applicable
8 Selenium Sulfide, Ketoconazole and Ciclopirox Shampoo as Additional Treatments for Tinea Capitis (Scalp Ringworm) Completed NCT00127868 Not Applicable oral griseofulvin, selenium sulfide shampoo 1%, ciclopirox shampoo , ketoconazole shampoo 2%, baby shampoo
9 The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation Completed NCT00224926
10 Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation Completed NCT00590421
11 Relevance of Trichoscopy in Differential Diagnosis of Focal Non-cicatricial Alopecia in Children Not yet recruiting NCT03260777
12 Trichoscopy in Diagnosis of Immunobollous Diseases Not yet recruiting NCT03478072

Search NIH Clinical Center for Tinea Capitis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: tinea capitis

Genetic Tests for Tinea Capitis

Anatomical Context for Tinea Capitis

MalaCards organs/tissues related to Tinea Capitis:

42
Skin, Thyroid, Brain, Testes, Pituitary, B Cells

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Capitis:

20
Scalp, Hair Of Head, Eyebrow Or

Publications for Tinea Capitis

Articles related to Tinea Capitis:

(show top 50) (show all 866)
# Title Authors Year
1
An Undetected Case of Tinea Capitis in an Elderly Woman Affected by Dermatomyositis: How Trichoscopy Can Guide to the Right Diagnosis. ( 31049345 )
2019
2
Folliculotropic mycosis fungoides in a pediatric patient mimicking black dot tinea capitis. ( 30791127 )
2019
3
Clinico-mycological profile of tinea capitis and its comparative response to griseofulvin versus terbinafine. ( 31049453 )
2019
4
Tinea capitis in adults: A 18-year retrospective, single-centre study in Korea. ( 30980768 )
2019
5
A single typical trichoscopic feature is predictive of tinea capitis: a prospective multicentre study. ( 30844082 )
2019
6
Extensive tinea capitis and corporis in a child caused by Trichophyton verrucosum. ( 30799183 )
2019
7
A case report of tinea capitis in infant in first year of life. ( 30795738 )
2019
8
Scalp BCC's and meningioma following X-ray epilation for tinea capitis. ( 30378096 )
2019
9
Prevalence of Tinea Capitis among Children in Osogbo, Nigeria, and the Associated Risk Factors. ( 30691234 )
2019
10
Tinea Capitis Masquerading as Basal Cell Carcinoma. ( 30207532 )
2018
11
Basal cell carcinoma induced by therapeutic radiation for tinea capitis-clinicopathological study. ( 29464746 )
2018
12
Tinea capitis mimicking dissecting cellulitis in three children. ( 29265536 )
2018
13
The kerion: an angry tinea capitis. ( 27696388 )
2018
14
The survey of tinea capitis and scalp dermatophyte carriage in nursing home residents. ( 28525623 )
2018
15
Dermoscopy for discriminating between Trichophyton and Microsporum infections in tinea capitis. ( 29237094 )
2018
16
Tinea capitis-like infection caused by Rhodotorula mucilaginosa in a shelter for African Refugee Children in Northern Israel. ( 29247617 )
2018
17
Emergence of African species of dermatophytes in tinea capitis: A 17-year experience in a Montreal pediatric hospital. ( 29573445 )
2018
18
Antimicrobial Susceptibility of Tinea Capitis in Children from Egypt. ( 29692458 )
2018
19
Trichoscopy helps to predict the time point of clinical cure of tinea capitis. ( 29767838 )
2018
20
A Review of Tinea Capitis in a Cohort of Asian Children. ( 29777246 )
2018
21
Tinea Capitis in a Newborn. ( 29791821 )
2018
22
Trichoscopic features of tinea capitis in a straight-haired Hispanic woman. ( 30695983 )
2018
23
Tinea capitis in children: a systematic review of management. ( 29797669 )
2018
24
Tinea capitis: correlation of clinical presentations to agents identified in mycological culture. ( 29924231 )
2018
25
Kerion and tinea capitis. ( 29988774 )
2018
26
Three Skulls Dating from the French Revolutionary Years Diagnosed with Tinea Capitis: A Paleopathologic Approach. ( 30169450 )
2018
27
Reflectance confocal microscopy of tinea capitis: comparing images with results of dermoscopy and mycological exams. ( 30229878 )
2018
28
Morse code-like hairs in tinea capitis disappear after successful treatment. ( 30264392 )
2018
29
Utility of trichoscopy in tinea capitis. ( 30425136 )
2018
30
Pediatric tinea capitis caused by Trichophyton violaceum and Trichophyton soudanense in Rochester, Minnesota, United States. ( 30548845 )
2018
31
A prospective study of tinea capitis in children: making the diagnosis easier with a dermoscope. ( 30591075 )
2018
32
Molecular epidemiology and in vitro antifungal susceptibility of Trichophyton schoenleinii, agent of tinea capitis favosa. ( 30597639 )
2018
33
Trichoscopy as a useful method to differentiate tinea capitis from alopecia areata in children at Zagazig University Hospitals. ( 27654953 )
2017
34
Trichophyton rubrum tinea capitis in an HIV-positive patient with generalized dermatophytosis. ( 28050591 )
2017
35
Continuous increase of Trichophyton tonsurans as a cause of tinea capitis in the urban area of Paris, France: a 5-year-long study. ( 27744309 )
2017
36
TERT promoter mutations: a genetic signature of benign and malignant thyroid tumours occurring in the context of tinea capitis irradiation. ( 27760791 )
2017
37
Identification of the causative dermatophyte of tinea capitis in children attending Mbarara Regional Referral Hospital in Uganda by PCR-ELISA and comparison with conventional mycological diagnostic methods. ( 27760831 )
2017
38
Systemic antifungal therapy for tinea capitis in children: An abridged Cochrane Review. ( 27816294 )
2017
39
Cathelicidin (LL-37) level in the scalp hair of patients with tinea capitis. ( 27915299 )
2017
40
In Vitro Antifungal Susceptibility Profiles of 12 Antifungal Drugs against 55 Trichophyton schoenleinii Isolates from Tinea Capitis Favosa Patients in Iran, Turkey, and China. ( 27956429 )
2017
41
Ultraviolet dermoscopy for the diagnosis of tinea capitis. ( 28087021 )
2017
42
Tinea in Tots: Cases and Literature Review of Oral Antifungal Treatment of Tinea Capitis in Children under 2 Years of Age. ( 28088394 )
2017
43
Changing in the Epidemiology of Tinea Capitis among School Children in Egypt. ( 28223741 )
2017
44
Clinical and Laboratory Characteristics of a Tinea Capitis Outbreak Among Novice Buddhist Monks. ( 28318040 )
2017
45
Clinicoepidemiological and Mycological Study of Tinea Capitis in the Pediatric Population of Kashmir Valley: A Study from a Tertiary Care Centre. ( 28405548 )
2017
46
The identification and grading of the psychosocial impact of Tinea capitis in primary school children in a semi-urban area of Rivers State, Nigeria. ( 28492205 )
2017
47
Follow-up of tinea capitis with trichoscopy: a prospective clinical study. ( 28499060 )
2017
48
Analysis of trichoscopic signs observed in 24 patients presenting tinea capitis: Hypotheses based on physiopathology and proposed new classification. ( 28528735 )
2017
49
Epidemiological profile of tinea capitis in São Paulo City. ( 28538903 )
2017
50
Tinea Capitis by Microsporum audouinii: Case Reports and Review of Published Global Literature 2000-2016. ( 28736794 )
2017

Variations for Tinea Capitis

Expression for Tinea Capitis

Search GEO for disease gene expression data for Tinea Capitis.

Pathways for Tinea Capitis

GO Terms for Tinea Capitis

Molecular functions related to Tinea Capitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 8.8 ARSI MBTPS2 PPA2

Sources for Tinea Capitis

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
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34 ICD10
35 ICD10 via Orphanet
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45 MeSH
46 MESH via Orphanet
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50 NCI
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52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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