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MCID: TNC003
MIFTS: 40

Tinea Corporis

Categories: Infectious diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Tinea Corporis

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MalaCards integrated aliases for Tinea Corporis:

Name: Tinea Corporis 12 15 73
Dermatophytosis of the Trunk 12
Dermatophytosis of the Body 12

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Skin diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:12179
ICD9CM 35 110.5
SNOMED-CT 68 84849002
ICD10 33 B35.4
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Summaries for Tinea Corporis

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Disease Ontology : 12 A dermatophytosis that results in fungal infection located in skin, limited to the stratum corneum of the epidermis, has material basis in Ascomycota fungi that belong to a group called dermatophytes and has symptom itching, and has symptom red colored skin rash. The border of the rash lesions look scaly.

MalaCards based summary : Tinea Corporis, also known as dermatophytosis of the trunk, is related to tinea cruris and dermatophytosis, and has symptoms including itching and red colored skin rash. An important gene associated with Tinea Corporis is SQLE (Squalene Epoxidase), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. The drugs Miconazole and Naftifine have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and bone, and related phenotype is integument.

Wikipedia : 76 Tinea corporis (also known as ringworm,tinea circinata, and tinea glabrosa) is a superficial fungal... more...

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Related Diseases for Tinea Corporis

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Diseases related to Tinea Corporis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 tinea cruris 31.5 DEFB4A SQLE
2 dermatophytosis 31.1 DEFB4A SQLE
3 tinea pedis 30.9 ARSI SQLE
4 psoriasis 30.1 DEFB4A KRT16 KRT17
5 skin disease 30.0 DEFB4A KRT16 KRT17
6 lichen planus 29.8 DEFB4A KRT16
7 tinea imbricata 11.6
8 tinea profunda 11.3
9 tinea capitis 10.5
10 ichthyosis 10.3
11 human immunodeficiency virus infectious disease 10.3
12 lupus erythematosus 10.3
13 mycosis fungoides 10.2
14 cutaneous lupus erythematosus 10.2
15 impetigo 10.2
16 subacute cutaneous lupus erythematosus 10.2
17 ichthyosis vulgaris 10.1
18 ichthyosis, x-linked 10.1
19 basal cell carcinoma 1 10.1
20 polyarteritis nodosa, childhood-onset 10.1
21 cutaneous candidiasis 10.1
22 graves' disease 10.1
23 tinea unguium 10.1
24 tinea manuum 10.1
25 candidiasis 10.1
26 neuritis 10.1
27 basal cell carcinoma 10.1
28 porokeratosis 10.1
29 infiltrative basal cell carcinoma 10.1
30 scabies 10.1
31 bullous pemphigoid 10.1
32 herpes zoster 10.1
33 tinea nigra 10.1
34 pityriasis versicolor 10.1
35 parapsoriasis 10.1
36 cutaneous larva migrans 10.1
37 linear iga disease 10.1
38 perniosis 10.1
39 discoid lupus erythematosus 10.1
40 palmoplantar keratoderma, bothnian type 10.0 KRT16 KRT17
41 median rhomboid glossitis 10.0 KRT16 KRT17
42 steatocystoma multiplex 10.0 KRT16 KRT17
43 bowen's disease 10.0 KRT16 KRT17
44 keratoacanthoma 9.9 KRT16 KRT17
45 pachyonychia congenita 1 9.9 KRT16 KRT17
46 primary cutaneous amyloidosis 9.9 KRT16 KRT17
47 monilethrix 9.9 KRT16 KRT17
48 cholesteatoma of middle ear 9.9 DEFB4A KRT16
49 epidermolytic hyperkeratosis 9.9 KRT16 KRT17

Graphical network of the top 20 diseases related to Tinea Corporis:



Diseases related to Tinea Corporis
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Symptoms & Phenotypes for Tinea Corporis

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Symptoms:

12
  • • itching
  • • red colored skin rash

MGI Mouse Phenotypes related to Tinea Corporis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.92 ALOXE3 KRT16 KRT17 SQLE
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Drugs & Therapeutics for Tinea Corporis

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Drugs for Tinea Corporis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
2
Naftifine Approved Phase 4 65472-88-0 47641 73342
3 Anti-Infective Agents Phase 4,Phase 3
4 Antifungal Agents Phase 4,Phase 3
5
Tolnaftate Approved, Investigational, Vet_approved Phase 3 2398-96-1 5510
6
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
7 Dermatologic Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open Label Pharmacokinetic Study of Naftin for Tinea Corporis Completed NCT02466867 Phase 4 Naftin® Cream, 2% (younger pediatric cohort);Naftin® Cream, 2% (older pediatric cohort)
2 Safety and Efficacy of Product 33525 in Pediatric Subjects With Tinea Corporis Completed NCT02767947 Phase 4 Luliconazole Cream 1%;Vehicle Cream
3 Pediatric Subjects With Tinea Corporis Completed NCT02227290 Phase 4 Naftin Cream;Placebo Cream
4 Evaluate the Efficacy and Safety of Tolnaftate Cream in the Treatment of Patients With Fungal Infections Unknown status NCT01105013 Phase 3 Clotrimazole
5 Safety of a Topical Antifungal Treatment for Tinea Cruris, Tinea Pedis and Tinea Corporis Completed NCT01349998 Phase 3 Product 33525
6 Evaluation of Preclinical Toxicity andTherapeutic Efficacy of Kandhaga Rasayanam in Padarthamarai Completed NCT02238912 Phase 2 kandhaga rasayanam
7 Senna Alata Leaf Decoction as a Treatment for Tinea Imbricata Completed NCT03745183 Not Applicable
8 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo Active, not recruiting NCT02902822 Not Applicable

Search NIH Clinical Center for Tinea Corporis

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Genetic Tests for Tinea Corporis

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Anatomical Context for Tinea Corporis

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The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Corporis:

19
Skin

MalaCards organs/tissues related to Tinea Corporis:

41
Skin, Bone, Testes, Thyroid, T Cells, Bone Marrow
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Publications for Tinea Corporis

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Articles related to Tinea Corporis:

(show top 50) (show all 230)
# Title Authors Year
1
Ein Fall von Tinea corporis am Arm, verursacht durch Nannizzia gypsea, mit dermatoskopischen Bildern. ( 29873917 )
2018
2
Infiltrative basal cell carcinoma mimicking tinea corporis. ( 29634889 )
2018
3
Is Antifungal Resistance a Cause for Treatment Failure in Dermatophytosis: A Study Focused on Tinea Corporis and Cruris from a Tertiary Centre? ( 29644192 )
2018
4
Current Trends of Using Systemic Antifungal Drugs and their Comparative Efficacy in Tinea Corporis and Tinea Cruris in Outpatient Department of Dermatology in a Tertiary Level Hospital. ( 29459592 )
2018
5
A case of tinea corporis on the arm caused by Nannizzia gypsea with dermatoscopic images. ( 29873907 )
2018
6
Tinea corporis by Microsporum canis in mycological laboratory staff: Unexpected results of epidemiological investigation. ( 30030967 )
2018
7
Tinea corporis by Microsporum audouinii in a female chimpanzee (Pan troglodytes) from Guinea-Bissau: A case report. ( 30142242 )
2018
8
Correlation of In Vitro Susceptibility Based on MICs and Squalene Epoxidase Mutations with Clinical Response to Terbinafine in Patients with Tinea Corporis/Cruris. ( 30275090 )
2018
9
A novel dermatophyte relative, Nannizzia perplicata sp. nov., isolated from a case of tinea corporis in the United Kingdom. ( 30329066 )
2018
10
Tinea Corporis Due to Trichophyton erinacei Probably Transmitted from a Hedgehog. ( 30504619 )
2018
11
Analysis on curative effects and safety of 2% liranaftate ointment in treating tinea pedis and tinea corporis & cruris. ( 28671089 )
2017
12
Porokeratosis Ptychotropica Coexisting with Tinea Corporis. ( 28761308 )
2017
13
Case Report of Onychomycosis and Tinea Corporis Due to Microsporum gypseum. ( 28817957 )
2017
14
Umbilical Psoriasis versus Tinea Corporis in Infants: A Simple Clinical Diagnosis/Image View. ( 28302469 )
2017
15
Tinea corporis caused by Trichophyton equinum in a rider and review of the literature. ( 28879496 )
2017
16
The association of isoconazole-diflucortolone in the treatment of pediatric tinea corporis. ( 28753055 )
2017
17
Case of inflammatory tinea corporis affecting the dorsal surface of the thumb in a nail salon technician. ( 28714099 )
2017
18
Neonatal tinea corporis. ( 29020896 )
2017
19
Unusual Presentation of Tinea Corporis Associated With the Use of a Microneedling Device. ( 29025223 )
2017
20
Tinea corporis presenting as disseminated verrucous plaques caused by Arthroderma incurvatum in a young Indian boy. ( 28731578 )
2017
21
A Case of Tinea Corporis due to Trichophyton tonsurans that Manifested as Impetigo. ( 27581776 )
2016
22
Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review. ( 27057486 )
2016
23
Kerion and Tinea Corporis Caused by Rabbit-Derived Trichophyton interdigitale in Three Siblings and One Consulting Doctor Using I^-Tubulin Gene to Identify the Pathogen. ( 27115611 )
2016
24
Pyocyanin as anti-tyrosinase and anti tinea corporis: A novel treatment study. ( 27671284 )
2016
25
Tinea corporis in a wrestling team cheerleader. ( 28492027 )
2016
26
Efficacy and Safety of Naftifine HCl Cream 2% in the Treatment of Pediatric Subjects With Tinea Corporis. ( 27272083 )
2016
27
Tinea corporis caused by Arthroderma benhamiae in a child. ( 27747922 )
2016
28
Tinea Corporis, Caused by Microsporum Canis - a Case Report From Kosovo. ( 26622092 )
2015
29
Neonatal tinea corporis due to a novel strain of Trichophyton rubrum. ( 26767757 )
2015
30
Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature. ( 25775632 )
2015
31
Tinea corporis on the stump leg with Trichophyton rubrum infection. ( 26288747 )
2015
32
Tinea corporis due to Trichophyton violaceum: A report of two cases. ( 26470976 )
2015
33
What is your diagnosis? Tinea corporis. ( 26682558 )
2015
34
Dermoscopic Visualization of Vellus Hair Involvement in Tinea Corporis: A Criterion for Systemic Antifungal Therapy? ( 26205739 )
2015
35
Chronically Recurrent and Widespread Tinea Corporis Due to Trichophyton rubrum in an Immunocompetent Patient. ( 25487974 )
2015
36
Comparison of topical anti- fungal agents sertaconazole and clotrimazole in the treatment of tinea corporis-an observational study. ( 25386455 )
2014
37
Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris. ( 24860743 )
2014
38
Evidence based topical treatments for tinea cruris and tinea corporis: A summary of a Cochrane systematic review. ( 25294700 )
2014
39
Topical antifungal treatments for tinea cruris and tinea corporis. ( 25090020 )
2014
40
Microsporum aenigmaticum sp. nov. from M. gypseum complex, isolated as a cause of tinea corporis. ( 24625678 )
2014
41
Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature. ( 25277164 )
2014
42
Diagnostic applicability of confocal laser scanning microscopy in tinea corporis. ( 24073912 )
2013
43
Effective treatment of tinea corporis due to Trichophyton mentagrophytes with combined isoconazole nitrate and diflucortolone valerate therapy. ( 23574023 )
2013
44
Tinea corporis due to Trichophyton mentagrophytes and Trichophyton tonsurans mimicking tinea imbricata. ( 23760341 )
2013
45
Cutaneous larva migrans masquerading as tinea corporis: a case report. ( 24298515 )
2013
46
Crusted scabies and tinea corporis after treatment of presumed bullous pemphigoid. ( 24195092 )
2013
47
Microsporum canis infection in three familial cases with tinea capitis and tinea corporis. ( 23918090 )
2013
48
Misdiagnosed zoophile tinea faciei and tinea corporis effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy. ( 23574022 )
2013
49
Ichthyosis associated with widespread tinea corporis: report of three cases. ( 24068140 )
2013
50
Tinea corporis in a mixed martial arts fighter. ( 23109614 )
2013
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Variations for Tinea Corporis

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Expression for Tinea Corporis

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Search GEO for disease gene expression data for Tinea Corporis.
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Pathways for Tinea Corporis

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Pathways related to Tinea Corporis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Cytoskeleton remodeling Neurofilaments 22
Show member pathways
 10.66 KRT16 KRT17
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GO Terms for Tinea Corporis

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Cellular components related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.62 KRT16 KRT17

Biological processes related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.32 KRT16 KRT17
2 cytoskeleton organization GO:0007010 9.26 KRT16 KRT17
3 cornification GO:0070268 9.16 KRT16 KRT17
4 epidermis development GO:0008544 8.96 KRT16 KRT17
5 establishment of skin barrier GO:0061436 8.62 ALOXE3 KRT16

Molecular functions related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 KRT16 KRT17
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Sources for Tinea Corporis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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