MCID: TNC003
MIFTS: 40

Tinea Corporis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Corporis

MalaCards integrated aliases for Tinea Corporis:

Name: Tinea Corporis 12 15 74
Dermatophytosis of the Trunk 12
Dermatophytosis of the Body 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12179
ICD9CM 36 110.5
SNOMED-CT 69 84849002
ICD10 34 B35.4

Summaries for Tinea Corporis

Disease Ontology : 12 A dermatophytosis that results in fungal infection located in skin, limited to the stratum corneum of the epidermis, has material basis in Ascomycota fungi that belong to a group called dermatophytes and has symptom itching, and has symptom red colored skin rash. The border of the rash lesions look scaly.

MalaCards based summary : Tinea Corporis, also known as dermatophytosis of the trunk, is related to dermatophytosis and tinea cruris, and has symptoms including itching and red colored skin rash. An important gene associated with Tinea Corporis is SQLE (Squalene Epoxidase), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. The drugs Miconazole and Naftifine have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and testes, and related phenotype is integument.

Wikipedia : 77 Tinea corporis, also known as ringworm, is a superficial fungal infection (dermatophytosis) of the arms... more...

Related Diseases for Tinea Corporis

Diseases related to Tinea Corporis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 dermatophytosis 32.0 DEFB4A SQLE
2 tinea cruris 31.6 DEFB4A SQLE
3 tinea pedis 31.2 ARSI SQLE
4 psoriasis 29.9 KRT16 KRT17
5 lichen planus 29.9 DEFB4A KRT16
6 skin disease 29.8 DEFB4A KRT16 KRT17
7 tinea imbricata 11.7
8 tinea profunda 11.3
9 tinea capitis 10.5
10 ichthyosis 10.3
11 human immunodeficiency virus infectious disease 10.3
12 lupus erythematosus 10.3
13 mycosis fungoides 10.2
14 cutaneous lupus erythematosus 10.2
15 impetigo 10.2
16 subacute cutaneous lupus erythematosus 10.2
17 ichthyosis vulgaris 10.1
18 arts syndrome 10.1
19 ichthyosis, x-linked 10.1
20 basal cell carcinoma 1 10.1
21 superficial mycosis 10.1
22 cutaneous candidiasis 10.1
23 graves' disease 10.1
24 tinea unguium 10.1
25 tinea manuum 10.1
26 norwegian scabies 10.1
27 candidiasis 10.1
28 dermatomycosis 10.1
29 neuritis 10.1
30 basal cell carcinoma 10.1
31 porokeratosis 10.1
32 infiltrative basal cell carcinoma 10.1
33 pustulosis of palm and sole 10.1
34 spindle cell hemangioma 10.1
35 lymphopenia 10.1
36 acquired immunodeficiency syndrome 10.1
37 scabies 10.1
38 bullous pemphigoid 10.1
39 herpes zoster 10.1
40 tinea nigra 10.1
41 pityriasis versicolor 10.1
42 parapsoriasis 10.1
43 cutaneous larva migrans 10.1
44 perniosis 10.1
45 discoid lupus erythematosus 10.1
46 palmoplantar keratoderma, bothnian type 10.0 KRT16 KRT17
47 median rhomboid glossitis 10.0 KRT16 KRT17
48 steatocystoma multiplex 9.9 KRT16 KRT17
49 bowen's disease 9.9 KRT16 KRT17
50 keratoacanthoma 9.9 KRT16 KRT17

Graphical network of the top 20 diseases related to Tinea Corporis:



Diseases related to Tinea Corporis

Symptoms & Phenotypes for Tinea Corporis

Symptoms:

12
  • itching
  • red colored skin rash

MGI Mouse Phenotypes related to Tinea Corporis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.92 ALOXE3 KRT16 KRT17 SQLE

Drugs & Therapeutics for Tinea Corporis

Drugs for Tinea Corporis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
2
Naftifine Approved Phase 4 65472-88-0 47641 73342
3
Luliconazole Approved Phase 4 187164-19-8
4
Itraconazole Approved, Investigational Phase 4 84625-61-6 55283
5 Antifungal Agents Phase 4,Phase 3
6 Anti-Infective Agents Phase 4,Phase 3
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
8 Hormones Phase 4
9 Steroid Synthesis Inhibitors Phase 4
10 Hormone Antagonists Phase 4
11
Hydroxyitraconazole Phase 4
12 Cytochrome P-450 CYP3A Inhibitors Phase 4
13 Cytochrome P-450 Enzyme Inhibitors Phase 4
14
Tolnaftate Approved, Investigational, Vet_approved Phase 3 2398-96-1 5510
15
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
16 Cathartics Not Applicable
17 Laxatives Not Applicable
18 Gastrointestinal Agents Not Applicable
19 Sennoside A&B Not Applicable
20 Senna Not Applicable
21 Dermatologic Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open Label Pharmacokinetic Study of Naftin for Tinea Corporis Completed NCT02466867 Phase 4 Naftin® Cream, 2% (younger pediatric cohort);Naftin® Cream, 2% (older pediatric cohort)
2 Safety and Efficacy of Product 33525 in Pediatric Subjects With Tinea Corporis Completed NCT02767947 Phase 4 Luliconazole Cream 1%;Vehicle Cream
3 Pediatric Subjects With Tinea Corporis Completed NCT02227290 Phase 4 Naftin Cream;Placebo Cream
4 A Study of Itraconazole in the Management of Superficial Fungal Infections in India Not yet recruiting NCT03923010 Phase 4 Itraconazole
5 Evaluate the Efficacy and Safety of Tolnaftate Cream in the Treatment of Patients With Fungal Infections Unknown status NCT01105013 Phase 3 Clotrimazole
6 Safety of a Topical Antifungal Treatment for Tinea Cruris, Tinea Pedis and Tinea Corporis Completed NCT01349998 Phase 3 Product 33525
7 Evaluation of Preclinical Toxicity andTherapeutic Efficacy of Kandhaga Rasayanam in Padarthamarai Completed NCT02238912 Phase 2 kandhaga rasayanam
8 Senna Alata Leaf Decoction as a Treatment for Tinea Imbricata Completed NCT03745183 Not Applicable
9 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo Completed NCT02902822 Not Applicable

Search NIH Clinical Center for Tinea Corporis

Genetic Tests for Tinea Corporis

Anatomical Context for Tinea Corporis

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Corporis:

20
Skin

MalaCards organs/tissues related to Tinea Corporis:

42
Skin, Testes, Thyroid, T Cells, Bone Marrow

Publications for Tinea Corporis

Articles related to Tinea Corporis:

(show top 50) (show all 231)
# Title Authors Year
1
Risk factors for chronic and chronic-relapsing tinea corporis, tinea cruris and tinea faciei: Results of a case-control study. ( 30719987 )
2019
2
Infiltrative basal cell carcinoma mimicking tinea corporis. ( 29634889 )
2018
3
Is Antifungal Resistance a Cause for Treatment Failure in Dermatophytosis: A Study Focused on Tinea Corporis and Cruris from a Tertiary Centre? ( 29644192 )
2018
4
The association of isoconazole-diflucortolone in the treatment of pediatric tinea corporis. ( 28753055 )
2018
5
Case Report of Onychomycosis and Tinea Corporis Due to Microsporum gypseum. ( 28817957 )
2018
6
Tinea corporis caused by Trichophyton equinum in a rider and review of the literature. ( 28879496 )
2018
7
Current Trends of Using Systemic Antifungal Drugs and their Comparative Efficacy in Tinea Corporis and Tinea Cruris in Outpatient Department of Dermatology in a Tertiary Level Hospital. ( 29459592 )
2018
8
A case of tinea corporis on the arm caused by Nannizzia gypsea with dermatoscopic images. ( 29873907 )
2018
9
Ein Fall von Tinea corporis am Arm, verursacht durch Nannizzia gypsea, mit dermatoskopischen Bildern. ( 29873917 )
2018
10
Tinea corporis by Microsporum canis in mycological laboratory staff: Unexpected results of epidemiological investigation. ( 30030967 )
2018
11
Tinea corporis by Microsporum audouinii in a female chimpanzee (Pan troglodytes) from Guinea-Bissau: A case report. ( 30142242 )
2018
12
Correlation of In Vitro Susceptibility Based on MICs and Squalene Epoxidase Mutations with Clinical Response to Terbinafine in Patients with Tinea Corporis/Cruris. ( 30275090 )
2018
13
A novel dermatophyte relative, Nannizzia perplicata sp. nov., isolated from a case of tinea corporis in the United Kingdom. ( 30329066 )
2018
14
Tinea Corporis Due to Trichophyton erinacei Probably Transmitted from a Hedgehog. ( 30504619 )
2018
15
Porokeratosis Ptychotropica Coexisting with Tinea Corporis. ( 28761308 )
2017
16
Umbilical Psoriasis versus Tinea Corporis in Infants: A Simple Clinical Diagnosis/Image View. ( 28302469 )
2017
17
Analysis on curative effects and safety of 2% liranaftate ointment in treating tinea pedis and tinea corporis & cruris. ( 28671089 )
2017
18
Case of inflammatory tinea corporis affecting the dorsal surface of the thumb in a nail salon technician. ( 28714099 )
2017
19
Tinea corporis presenting as disseminated verrucous plaques caused by Arthroderma incurvatum in a young Indian boy. ( 28731578 )
2017
20
Neonatal tinea corporis. ( 29020896 )
2017
21
Unusual Presentation of Tinea Corporis Associated With the Use of a Microneedling Device. ( 29025223 )
2017
22
A Case of Tinea Corporis due to Trichophyton tonsurans that Manifested as Impetigo. ( 27581776 )
2016
23
Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review. ( 27057486 )
2016
24
Kerion and Tinea Corporis Caused by Rabbit-Derived Trichophyton interdigitale in Three Siblings and One Consulting Doctor Using β-Tubulin Gene to Identify the Pathogen. ( 27115611 )
2016
25
Efficacy and Safety of Naftifine HCl Cream 2% in the Treatment of Pediatric Subjects With Tinea Corporis. ( 27272083 )
2016
26
Pyocyanin as anti-tyrosinase and anti tinea corporis: A novel treatment study. ( 27671284 )
2016
27
Tinea corporis caused by Arthroderma benhamiae in a child. ( 27747922 )
2016
28
Tinea corporis in a wrestling team cheerleader. ( 28492027 )
2016
29
Evidence-based topical treatments for tinea cruris and tinea corporis: a summary of a Cochrane systematic review. ( 25294700 )
2015
30
Chronically recurrent and widespread tinea corporis due to Trichophyton rubrum in an immunocompetent patient. ( 25487974 )
2015
31
Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature. ( 25775632 )
2015
32
Dermoscopic Visualization of Vellus Hair Involvement in Tinea Corporis: A Criterion for Systemic Antifungal Therapy? ( 26205739 )
2015
33
Tinea corporis on the stump leg with Trichophyton rubrum infection. ( 26288747 )
2015
34
Tinea corporis due to Trichophyton violaceum: A report of two cases. ( 26470976 )
2015
35
Tinea Corporis, Caused by Microsporum Canis - a Case Report From Kosovo. ( 26622092 )
2015
36
What is your diagnosis? Tinea corporis. ( 26682558 )
2015
37
Neonatal tinea corporis due to a novel strain of Trichophyton rubrum. ( 26767757 )
2015
38
Microsporum aenigmaticum sp. nov. from M. gypseum complex, isolated as a cause of tinea corporis. ( 24625678 )
2014
39
Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris. ( 24860743 )
2014
40
Topical antifungal treatments for tinea cruris and tinea corporis. ( 25090020 )
2014
41
Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature. ( 25277164 )
2014
42
Comparison of topical anti- fungal agents sertaconazole and clotrimazole in the treatment of tinea corporis-an observational study. ( 25386455 )
2014
43
Crusted scabies and tinea corporis after treatment of presumed bullous pemphigoid. ( 24195092 )
2013
44
Cutaneous larva migrans masquerading as tinea corporis: a case report. ( 24298515 )
2013
45
Ichthyosis associated with widespread tinea corporis: report of three cases. ( 24068140 )
2013
46
Microsporum canis infection in three familial cases with tinea capitis and tinea corporis. ( 23918090 )
2013
47
Tinea corporis in a mixed martial arts fighter. ( 23109614 )
2013
48
Misdiagnosed zoophile tinea faciei and tinea corporis effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy. ( 23574022 )
2013
49
Effective treatment of tinea corporis due to Trichophyton mentagrophytes with combined isoconazole nitrate and diflucortolone valerate therapy. ( 23574023 )
2013
50
Tinea corporis due to Trichophyton mentagrophytes and Trichophyton tonsurans mimicking tinea imbricata. ( 23760341 )
2013

Variations for Tinea Corporis

Expression for Tinea Corporis

Search GEO for disease gene expression data for Tinea Corporis.

Pathways for Tinea Corporis

Pathways related to Tinea Corporis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.66 KRT16 KRT17

GO Terms for Tinea Corporis

Cellular components related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.62 KRT16 KRT17

Biological processes related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.32 KRT16 KRT17
2 cytoskeleton organization GO:0007010 9.26 KRT16 KRT17
3 cornification GO:0070268 9.16 KRT16 KRT17
4 epidermis development GO:0008544 8.96 KRT16 KRT17
5 establishment of skin barrier GO:0061436 8.62 ALOXE3 KRT16

Molecular functions related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 KRT16 KRT17

Sources for Tinea Corporis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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