MCID: TNC003
MIFTS: 39

Tinea Corporis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Corporis

MalaCards integrated aliases for Tinea Corporis:

Name: Tinea Corporis 12 15 73
Dermatophytosis of the Trunk 12
Dermatophytosis of the Body 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12179
ICD9CM 35 110.5
ICD10 33 B35.4

Summaries for Tinea Corporis

Disease Ontology : 12 A dermatophytosis that results in fungal infection located in skin, limited to the stratum corneum of the epidermis, has material basis in Ascomycota fungi that belong to a group called dermatophytes and has symptom itching, and has symptom red colored skin rash. The border of the rash lesions look scaly.

MalaCards based summary : Tinea Corporis, also known as dermatophytosis of the trunk, is related to tinea cruris and dermatophytosis, and has symptoms including itching and red colored skin rash. An important gene associated with Tinea Corporis is SQLE (Squalene Epoxidase), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. The drugs Miconazole and Naftifine have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and testes, and related phenotype is integument.

Wikipedia : 76 Tinea corporis (also known as ringworm,tinea circinata, and tinea glabrosa) is a superficial fungal... more...

Related Diseases for Tinea Corporis

Diseases related to Tinea Corporis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Related Disease Score Top Affiliating Genes
1 tinea cruris 31.6 DEFB4A SQLE
2 dermatophytosis 30.7 DEFB4A SQLE
3 tinea pedis 30.5 ARSI SQLE
4 skin disease 29.2 DEFB4A KRT16 KRT17
5 lichen planus 29.0 DEFB4A KRT16
6 psoriasis 29.0 DEFB4A KRT16 KRT17
7 tinea imbricata 11.5
8 tinea profunda 11.1
9 tinea capitis 10.3
10 cutaneous mycosis 10.2 DEFB4A SQLE
11 ichthyosis 10.2
12 lupus erythematosus 10.2
13 basal cell carcinoma 1 10.1
14 cutaneous lupus erythematosus 10.1
15 basal cell carcinoma 10.1
16 impetigo 10.1
17 subacute cutaneous lupus erythematosus 10.1
18 pachyonychia congenita 2 10.0 KRT16 KRT17
19 median rhomboid glossitis 10.0 KRT16 KRT17
20 steatocystoma multiplex 10.0 KRT16 KRT17
21 bowen's disease 9.9 KRT16 KRT17
22 glossitis 9.9 KRT16 KRT17
23 ichthyosis vulgaris 9.9
24 mycosis fungoides 9.9
25 ichthyosis, x-linked 9.9
26 cutaneous candidiasis 9.9
27 graves' disease 9.9
28 tinea unguium 9.9
29 tinea manuum 9.9
30 candidiasis 9.9
31 neuritis 9.9
32 porokeratosis 9.9
33 infiltrative basal cell carcinoma 9.9
34 thyroiditis 9.9
35 scabies 9.9
36 bullous pemphigoid 9.9
37 herpes zoster 9.9
38 tinea nigra 9.9
39 pityriasis versicolor 9.9
40 parapsoriasis 9.9
41 cutaneous larva migrans 9.9
42 linear iga disease 9.9
43 perniosis 9.9
44 discoid lupus erythematosus 9.9
45 palmoplantar keratoderma, epidermolytic 9.9 KRT16 KRT17
46 palmoplantar keratoderma, nonepidermolytic 9.9 KRT16 KRT17
47 pachyonychia congenita 1 9.8 KRT16 KRT17
48 keratoacanthoma 9.8 KRT16 KRT17
49 primary cutaneous amyloidosis 9.8 KRT16 KRT17
50 epidermolytic hyperkeratosis 9.7 KRT16 KRT17

Graphical network of the top 20 diseases related to Tinea Corporis:



Diseases related to Tinea Corporis

Symptoms & Phenotypes for Tinea Corporis

Symptoms:

12
  • itching
  • red colored skin rash

MGI Mouse Phenotypes related to Tinea Corporis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.92 ALOXE3 KRT16 KRT17 SQLE

Drugs & Therapeutics for Tinea Corporis

Drugs for Tinea Corporis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3 22916-47-8 4189
2
Naftifine Approved Phase 4 65472-88-0 73342 47641
3 Antifungal Agents Phase 4,Phase 3
4 Anti-Infective Agents Phase 4,Phase 3
5
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
6
Tolnaftate Approved, Investigational, Vet_approved Phase 3 2398-96-1 5510
7 Dermatologic Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open Label Pharmacokinetic Study of Naftin for Tinea Corporis Completed NCT02466867 Phase 4 Naftin® Cream, 2% (younger pediatric cohort);Naftin® Cream, 2% (older pediatric cohort)
2 Safety and Efficacy of Product 33525 in Pediatric Subjects With Tinea Corporis Completed NCT02767947 Phase 4 Luliconazole Cream 1%;Vehicle Cream
3 Pediatric Subjects With Tinea Corporis Completed NCT02227290 Phase 4 Naftin Cream;Placebo Cream
4 Evaluate the Efficacy and Safety of Tolnaftate Cream in the Treatment of Patients With Fungal Infections Unknown status NCT01105013 Phase 3 Clotrimazole
5 Safety of a Topical Antifungal Treatment for Tinea Cruris, Tinea Pedis and Tinea Corporis Completed NCT01349998 Phase 3 Product 33525
6 Evaluation of Preclinical Toxicity andTherapeutic Efficacy of Kandhaga Rasayanam in Padarthamarai Completed NCT02238912 Phase 2 kandhaga rasayanam
7 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo Active, not recruiting NCT02902822 Not Applicable

Search NIH Clinical Center for Tinea Corporis

Genetic Tests for Tinea Corporis

Anatomical Context for Tinea Corporis

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Corporis:

19
Skin

MalaCards organs/tissues related to Tinea Corporis:

41
Skin, Testes, T Cells, Thyroid, Bone, Bone Marrow

Publications for Tinea Corporis

Articles related to Tinea Corporis:

(show top 50) (show all 215)
# Title Authors Year
1
Ein Fall von Tinea corporis am Arm, verursacht durch Nannizzia gypsea, mit dermatoskopischen Bildern. ( 29873917 )
2018
2
Infiltrative basal cell carcinoma mimicking tinea corporis. ( 29634889 )
2018
3
Is Antifungal Resistance a Cause for Treatment Failure in Dermatophytosis: A Study Focused on Tinea Corporis and Cruris from a Tertiary Centre? ( 29644192 )
2018
4
Current Trends of Using Systemic Antifungal Drugs and their Comparative Efficacy in Tinea Corporis and Tinea Cruris in Outpatient Department of Dermatology in a Tertiary Level Hospital. ( 29459592 )
2018
5
A case of tinea corporis on the arm caused by Nannizzia gypsea with dermatoscopic images. ( 29873907 )
2018
6
Analysis on curative effects and safety of 2% liranaftate ointment in treating tinea pedis and tinea corporis & cruris. ( 28671089 )
2017
7
Porokeratosis Ptychotropica Coexisting with Tinea Corporis. ( 28761308 )
2017
8
Case Report of Onychomycosis and Tinea Corporis Due to Microsporum gypseum. ( 28817957 )
2017
9
Umbilical Psoriasis versus Tinea Corporis in Infants: A Simple Clinical Diagnosis/Image View. ( 28302469 )
2017
10
Tinea corporis caused by Trichophyton equinum in a rider and review of the literature. ( 28879496 )
2017
11
The association of isoconazole-diflucortolone in the treatment of pediatric tinea corporis. ( 28753055 )
2017
12
Case of inflammatory tinea corporis affecting the dorsal surface of the thumb in a nail salon technician. ( 28714099 )
2017
13
Neonatal tinea corporis. ( 29020896 )
2017
14
Unusual Presentation of Tinea Corporis Associated With the Use of a Microneedling Device. ( 29025223 )
2017
15
Tinea corporis presenting as disseminated verrucous plaques caused by Arthroderma incurvatum in a young Indian boy. ( 28731578 )
2017
16
A Case of Tinea Corporis due to Trichophyton tonsurans that Manifested as Impetigo. ( 27581776 )
2016
17
Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review. ( 27057486 )
2016
18
Kerion and Tinea Corporis Caused by Rabbit-Derived Trichophyton interdigitale in Three Siblings and One Consulting Doctor Using I^-Tubulin Gene to Identify the Pathogen. ( 27115611 )
2016
19
Pyocyanin as anti-tyrosinase and anti tinea corporis: A novel treatment study. ( 27671284 )
2016
20
Tinea corporis in a wrestling team cheerleader. ( 28492027 )
2016
21
Efficacy and Safety of Naftifine HCl Cream 2% in the Treatment of Pediatric Subjects With Tinea Corporis. ( 27272083 )
2016
22
Tinea corporis caused by Arthroderma benhamiae in a child. ( 27747922 )
2016
23
Tinea Corporis, Caused by Microsporum Canis - a Case Report From Kosovo. ( 26622092 )
2015
24
Neonatal tinea corporis due to a novel strain of Trichophyton rubrum. ( 26767757 )
2015
25
Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature. ( 25775632 )
2015
26
Tinea corporis on the stump leg with Trichophyton rubrum infection. ( 26288747 )
2015
27
Tinea corporis due to Trichophyton violaceum: A report of two cases. ( 26470976 )
2015
28
What is your diagnosis? Tinea corporis. ( 26682558 )
2015
29
Dermoscopic Visualization of Vellus Hair Involvement in Tinea Corporis: A Criterion for Systemic Antifungal Therapy? ( 26205739 )
2015
30
Chronically Recurrent and Widespread Tinea Corporis Due to Trichophyton rubrum in an Immunocompetent Patient. ( 25487974 )
2015
31
Comparison of topical anti- fungal agents sertaconazole and clotrimazole in the treatment of tinea corporis-an observational study. ( 25386455 )
2014
32
Efficacy and safety of terbinafine hydrochloride 1% cream vs eberconazole nitrate 1% cream in localised tinea corporis and tinea cruris. ( 24860743 )
2014
33
Evidence based topical treatments for tinea cruris and tinea corporis: A summary of a Cochrane systematic review. ( 25294700 )
2014
34
Topical antifungal treatments for tinea cruris and tinea corporis. ( 25090020 )
2014
35
Microsporum aenigmaticum sp. nov. from M. gypseum complex, isolated as a cause of tinea corporis. ( 24625678 )
2014
36
Tinea cruris and tinea corporis masquerading as tinea indecisiva: case report and review of the literature. ( 25277164 )
2014
37
Diagnostic applicability of confocal laser scanning microscopy in tinea corporis. ( 24073912 )
2013
38
Effective treatment of tinea corporis due to Trichophyton mentagrophytes with combined isoconazole nitrate and diflucortolone valerate therapy. ( 23574023 )
2013
39
Tinea corporis due to Trichophyton mentagrophytes and Trichophyton tonsurans mimicking tinea imbricata. ( 23760341 )
2013
40
Cutaneous larva migrans masquerading as tinea corporis: a case report. ( 24298515 )
2013
41
Crusted scabies and tinea corporis after treatment of presumed bullous pemphigoid. ( 24195092 )
2013
42
Microsporum canis infection in three familial cases with tinea capitis and tinea corporis. ( 23918090 )
2013
43
Misdiagnosed zoophile tinea faciei and tinea corporis effectively treated with isoconazole nitrate and diflucortolone valerate combination therapy. ( 23574022 )
2013
44
Ichthyosis associated with widespread tinea corporis: report of three cases. ( 24068140 )
2013
45
Tinea corporis in a mixed martial arts fighter. ( 23109614 )
2013
46
Efficacy and Safety of Terbinafine Hydrochloride 1% Cream vs. Sertaconazole Nitrate 2% Cream in Tinea Corporis and Tinea Cruris: A Comparative Therapeutic Trial. ( 24249898 )
2013
47
Tinea corporis due to Trichophyton rubrum in a woman and Tinea capitis in her 15-day-old baby: molecular evidence of vertical transmission. ( 21997860 )
2012
48
Tinea corporis bullosa due to Trichophyton schoenleinii: case report. ( 22576942 )
2012
49
Radiation port dermatophytosis: tinea corporis occurring at the site of irradiated skin. ( 22301042 )
2012
50
Tinea corporis in a psoriatic patient. ( 21615530 )
2012

Variations for Tinea Corporis

Expression for Tinea Corporis

Search GEO for disease gene expression data for Tinea Corporis.

Pathways for Tinea Corporis

Pathways related to Tinea Corporis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.66 KRT16 KRT17

GO Terms for Tinea Corporis

Cellular components related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.62 KRT16 KRT17

Biological processes related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.16 KRT16 KRT17
2 epidermis development GO:0008544 8.96 KRT16 KRT17
3 establishment of skin barrier GO:0061436 8.62 ALOXE3 KRT16

Molecular functions related to Tinea Corporis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 KRT16 KRT17

Sources for Tinea Corporis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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