FAVUS
MCID: TNF001
MIFTS: 36

Tinea Favosa (FAVUS)

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Favosa

MalaCards integrated aliases for Tinea Favosa:

Name: Tinea Favosa 12 44 15 73
Favus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4336
ICD10 33 B35
MeSH 44 D014007
NCIt 50 C35072
SNOMED-CT 68 85375000
UMLS 73 C0040254

Summaries for Tinea Favosa

Disease Ontology : 12 A tinea capitis that results in fungal infection located in scalp, located in glabrous skin or located in nail, has material basis in Ascomycota fungi that belong to a group called dermatophytes and results in_formation_of scutula, yellowish cup-shaped crusts of dense masses of mycelium and epithelial debris, which develop at the surface of a hair follicle with the shaft in the center of the raised lesion. Removal of these crusts reveals an oozing, moist, red base. Later, atrophy of the skin occurs leaving a cicatricial alopecia and scarring.

MalaCards based summary : Tinea Favosa, also known as favus, is related to tinea capitis and choanal atresia, posterior. An important gene associated with Tinea Favosa is RDH11 (Retinol Dehydrogenase 11), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and Immune response Fc epsilon RI pathway. The drugs Estradiol and Polyestradiol phosphate have been mentioned in the context of this disorder. Affiliated tissues include skin, scalp and glabrous skin or, and related phenotypes are cellular and digestive/alimentary

Wikipedia : 76 Favus (of "favus" Latin for "honeycomb" or tinea favosa) is a disease usually affecting the scalp, but... more...

Related Diseases for Tinea Favosa

Graphical network of the top 20 diseases related to Tinea Favosa:



Diseases related to Tinea Favosa

Symptoms & Phenotypes for Tinea Favosa

MGI Mouse Phenotypes related to Tinea Favosa:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.05 CASP1 CHD7 CTSB KDR MAPK8 NLRP3
2 digestive/alimentary MP:0005381 10.04 CASP1 CHD7 CTSB FOXE1 MAPK8 NLRP3
3 homeostasis/metabolism MP:0005376 10.03 CASP1 CHD7 CTSB FOXE1 KDR MAPK8
4 growth/size/body region MP:0005378 10 CHD7 CTSB FOXE1 KDR MAPK8 NLRP3
5 endocrine/exocrine gland MP:0005379 9.95 CASP1 CHD7 CTSB FOXE1 MAPK8 NOS3
6 immune system MP:0005387 9.95 CASP1 CHD7 CTSB KDR MAPK8 NLRP3
7 mortality/aging MP:0010768 9.92 CASP1 CHD7 CTSB FOXE1 KDR MAPK8
8 integument MP:0010771 9.85 CASP1 CTSB FOXE1 KDR MAPK8 NLRP3
9 nervous system MP:0003631 9.8 CASP1 CHD7 CTSB KDR MAPK8 NLRP3
10 renal/urinary system MP:0005367 9.55 CASP1 CTSB MAPK8 NLRP3 NOS3
11 reproductive system MP:0005389 9.43 CASP1 CHD7 MAPK8 NLRP3 NOS3 RDH11
12 vision/eye MP:0005391 9.02 CHD7 KDR MAPK8 NOS3 RDH11

Drugs & Therapeutics for Tinea Favosa

Drugs for Tinea Favosa (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
2
Polyestradiol phosphate Approved Phase 2 28014-46-2
3 Estradiol valerate Approved, Investigational, Vet_approved Phase 2 979-32-8
4 Contraceptive Agents Phase 2
5 Hormone Antagonists Phase 2
6 Hormones Phase 2
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
8 Estrogens Phase 2
9 Estradiol 17 beta-cypionate Phase 2
10 Estradiol 3-benzoate Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass Terminated NCT01928082 Phase 2 Transdermal estradiol

Search NIH Clinical Center for Tinea Favosa

Cochrane evidence based reviews: tinea favosa

Genetic Tests for Tinea Favosa

Anatomical Context for Tinea Favosa

MalaCards organs/tissues related to Tinea Favosa:

41
Skin

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Favosa:

19
Scalp, Glabrous Skin Or

Publications for Tinea Favosa

Articles related to Tinea Favosa:

(show top 50) (show all 103)
# Title Authors Year
1
Disseminated Favus Caused by Microsporum gypseum in a Patient with Systemic Lupus Erythematosus. ( 26259050 )
2016
2
Generalized Favus: The Story of a Legendary Case of Tinea Favosa. ( 25583289 )
2015
3
Goya and tinea favosa. ( 25387510 )
2014
4
Cat favus caused by Microsporum incurvatum comb. nov.: the clinical and histopathological features and molecular phylogeny. ( 24625676 )
2014
5
Favus in an elderly Kashmiri female: A rare occurrence. ( 24082227 )
2013
6
Diversity of bacterial communities associated with the Indian Ocean sponge Tsitsikamma favus that contains the bioactive pyrroloiminoquinones, tsitsikammamine A and B. ( 22310802 )
2012
7
Favus of the scalp: an overview and update. ( 20411336 )
2010
8
Favus due to Trichophyton schoenleinii in a patient with metastatic bronchial carcinoma. ( 12786844 )
2003
9
Favus due to Trichophyton mentagrophytes var. quinckeanum. ( 12950911 )
2003
10
Factors controlling the expansion behavior of favia favus (Cnidaria: Scleractinia): effects of light, flow, and planktonic prey. ( 11341573 )
2001
11
Favus due to Trichophyton mentagrophytes var. quinckeanum. ( 9094471 )
1997
12
A focus of favus due to Trichophyton schoenleinii in Rio Grande do Sul, Brasil. ( 9394528 )
1997
13
Favus in a non-endemic area. ( 20944324 )
1997
14
Efficacy of miconazole nitrate against favus in oriental breed chickens. ( 8719227 )
1995
15
Favus in an ostrich. ( 7879374 )
1994
16
Favus in a backyard flock of game chickens. ( 1953587 )
1991
17
Image processing by microcomputer on ultrastructure of griseofulvin-resistant fungi in favus. ( 2348492 )
1990
18
A case of Wilson-Konovalov's disease, accompanied by considerable renal tubular dysfunctions in combination with favus. ( 2517891 )
1989
19
Ringworm infections in the nomadic Fulani of Nigeria, with particular reference to favus. ( 3344032 )
1988
20
Favus in a fighting cock caused by Microsporum gallinae. ( 6487194 )
1984
21
Experimental dermatophytosis: the clinical and histopathologic features of a mouse model using Trichophyton quinckeanum (mouse favus). ( 6886475 )
1983
22
Favus--a report of two cases. ( 6627734 )
1983
23
Favus. ( 7358450 )
1980
24
Favus: twenty indigenous cases in the province of Quebec. ( 718212 )
1978
25
Familial favus. ( 992991 )
1976
26
Circulating antibodies in human favus. ( 5003446 )
1971
27
Favus again mistaken for leprosy in the Renaissance. ( 4912759 )
1970
28
Affection of the arrectores pilorum muscles in favus. ( 4097856 )
1969
29
Human infections with mouse favus in a rural area of South Australia. ( 5823730 )
1969
30
Study of 73 cases of tinea capitis and tinea favosa in adults and adolescents. ( 5697378 )
1968
31
Favus mistaken for leprosy by artists of the renaissance. ( 4880388 )
1968
32
Experimental investigations into the therapeutic effect of griseogulvin in favus caused by Trichophyton schoenleinii. ( 5294590 )
1965
33
Favus. ( 5831923 )
1965
34
DEHYDROEMETINE IN FUNGUS INFECTION (TINEA FAVOSA). ( 14201655 )
1964
35
Human favus in Quebec. ( 13971502 )
1962
36
An endemic focus of favus in South Central Missouri. ( 14466664 )
1962
37
Favus in Kentucky: diagnosis, treatment and epidemiology. ( 14466896 )
1962
38
Comparative trial of fine-particle griseofulvin in favus. ( 14485822 )
1962
39
Griseofulvin treatment of superficial mycoses (including 7 cases of favus). ( 13707806 )
1960
40
Treatment of favus with griseofulvin. ( 13721255 )
1960
41
The effects of griseofulvin in favus. ( 13735062 )
1960
42
Mouse favus due to Trichophyton quinckeanum (Zopf) MacLeod & Muende: a reappraisal in the light of recent investigations. IV. ( 13757945 )
1960
43
Response of favus to griseofulvin. ( 13822255 )
1960
44
The treatment of favus with griseofulvin. ( 14410960 )
1960
45
Griseofulvin and favus. A report on work in progress. ( 14432442 )
1960
46
Favus treated with griseofulvin. ( 14441258 )
1960
47
Mouse favus due to Trichophyton quinckeanum (Zopf) Macleod & Muend: a reappraisal in the light of recent investigations. I-II. ( 14413149 )
1959
48
Mouse favus due to Trichophyton quinckeanum (Zopf) Macleod & Muende: a reappraisal in the light of recent investigations. III. ( 14413150 )
1959
49
Favus in Greenland. ( 14418081 )
1959
50
Griseofulvin in the treatment of favus. ( 14422958 )
1959

Variations for Tinea Favosa

Expression for Tinea Favosa

Search GEO for disease gene expression data for Tinea Favosa.

Pathways for Tinea Favosa

Pathways related to Tinea Favosa according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.61 CASP1 CTSB MAPK8 NLRP3
2
Show member pathways
12.23 KDR MAPK8 NOS3
3
Show member pathways
12.07 KDR MAPK8 NOS3
4
Show member pathways
12.06 KDR MAPK8 NOS3
5
Show member pathways
11.78 CASP1 MAPK8 NLRP3
6
Show member pathways
11.74 CASP1 MAPK8 NLRP3
7
Show member pathways
11.73 CASP1 KDR MAPK8
8
Show member pathways
11.69 KDR MAPK8 NOS3
9 11.47 KDR MAPK8 NOS3
10 11.37 MAPK8 NOS3
11 11.11 CASP1 NLRP3
12
Show member pathways
11.05 KDR MAPK8 NOS3
13 10.91 CHD7 MAPK8
14 10.78 KDR NOS3
15 10.68 CASP1 MAPK8 NLRP3

GO Terms for Tinea Favosa

Cellular components related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NLRP3 inflammasome complex GO:0072559 8.62 CASP1 NLRP3

Biological processes related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to cytokine stimulus GO:0071345 9.4 CASP1 MAPK8
2 positive regulation of blood vessel endothelial cell migration GO:0043536 9.37 KDR NOS3
3 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 9.32 CASP1 NLRP3
4 cellular response to organic substance GO:0071310 9.26 CASP1 MAPK8
5 blood vessel remodeling GO:0001974 9.16 CHD7 NOS3
6 positive regulation of interleukin-1 beta secretion GO:0050718 8.96 CASP1 NLRP3
7 cellular response to lipopolysaccharide GO:0071222 8.8 CASP1 MAPK8 NLRP3

Sources for Tinea Favosa

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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