FAVUS
MCID: TNF001
MIFTS: 41

Tinea Favosa (FAVUS)

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Tinea Favosa

MalaCards integrated aliases for Tinea Favosa:

Name: Tinea Favosa 12 44 15 17 72
Favus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4336
MeSH 44 D014007
NCIt 50 C35072
SNOMED-CT 68 85375000
ICD10 33 B35
UMLS 72 C0040254

Summaries for Tinea Favosa

Disease Ontology : 12 A tinea capitis that results in fungal infection located in scalp, located in glabrous skin or located in nail, has material basis in Ascomycota fungi that belong to a group called dermatophytes and results in formation of scutula, yellowish cup-shaped crusts of dense masses of mycelium and epithelial debris, which develop at the surface of a hair follicle with the shaft in the center of the raised lesion. Removal of these crusts reveals an oozing, moist, red base. Later, atrophy of the skin occurs leaving a cicatricial alopecia and scarring.

MalaCards based summary : Tinea Favosa, also known as favus, is related to dermatophytosis and tinea capitis. An important gene associated with Tinea Favosa is CHD7 (Chromodomain Helicase DNA Binding Protein 7), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and EPH-Ephrin signaling. The drugs Estradiol and Polyestradiol phosphate have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and testes, and related phenotypes are cellular and homeostasis/metabolism

Wikipedia : 75 Favus (Latin for "honeycomb") is a disease usually affecting the scalp, but occurring occasionally on... more...

Related Diseases for Tinea Favosa

Graphical network of the top 20 diseases related to Tinea Favosa:



Diseases related to Tinea Favosa

Symptoms & Phenotypes for Tinea Favosa

MGI Mouse Phenotypes related to Tinea Favosa:

46 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.08 CASP1 CHD7 CTSB KDR MAPK8 NLRP3
2 homeostasis/metabolism MP:0005376 10.06 CASP1 CHD7 CTSB KALRN KDR MAPK8
3 growth/size/body region MP:0005378 10.04 CHD7 CTSB KALRN KDR MAPK8 NLRP3
4 behavior/neurological MP:0005386 10.03 CHD7 CTSB KALRN KDR MAPK8 NOS3
5 cardiovascular system MP:0005385 10.02 CASP1 CHD7 KALRN KDR MAPK8 NOS3
6 digestive/alimentary MP:0005381 10 CASP1 CHD7 CTSB MAPK8 NLRP3 NOS3
7 endocrine/exocrine gland MP:0005379 9.99 CASP1 CHD7 CTSB KALRN MAPK8 NOS3
8 immune system MP:0005387 9.98 CASP1 CHD7 CTSB KDR MAPK8 NLRP3
9 mortality/aging MP:0010768 9.97 CASP1 CHD7 CTSB KALRN KDR MAPK8
10 hematopoietic system MP:0005397 9.95 CASP1 CHD7 KDR MAPK8 NLRP3 NOS3
11 integument MP:0010771 9.88 CASP1 CTSB KALRN KDR MAPK8 NLRP3
12 nervous system MP:0003631 9.86 CASP1 CHD7 CTSB KALRN KDR MAPK8
13 muscle MP:0005369 9.72 CHD7 KALRN KDR MAPK8 NOS3
14 normal MP:0002873 9.55 CTSB KALRN KDR NLRP3 NOS3
15 renal/urinary system MP:0005367 9.35 CASP1 CTSB MAPK8 NLRP3 NOS3
16 reproductive system MP:0005389 9.1 CASP1 CHD7 KALRN MAPK8 NLRP3 NOS3

Drugs & Therapeutics for Tinea Favosa

Drugs for Tinea Favosa (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 2 50-28-2 5757
2
Polyestradiol phosphate Approved Phase 2 28014-46-2
3 Estrogens Phase 2
4 Hormones Phase 2
5 Contraceptive Agents Phase 2
6 Hormone Antagonists Phase 2
7 Estradiol 17 beta-cypionate Phase 2
8 Estradiol 3-benzoate Phase 2
9 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass Terminated NCT01928082 Phase 2 Transdermal estradiol

Search NIH Clinical Center for Tinea Favosa

Cochrane evidence based reviews: tinea favosa

Genetic Tests for Tinea Favosa

Anatomical Context for Tinea Favosa

MalaCards organs/tissues related to Tinea Favosa:

41
Skin, Bone, Testes, Lymph Node, Endothelial

The Foundational Model of Anatomy Ontology organs/tissues related to Tinea Favosa:

19
Nail, Scalp, Glabrous Skin

Publications for Tinea Favosa

Articles related to Tinea Favosa:

(show top 50) (show all 294)
# Title Authors PMID Year
1
Favus of Scrotum Due to Trichophyton rubrum in Immunocompetent Patients: A Clinical, Mycological and Ultrastructural Study. 38
30976954 2019
2
Molecular epidemiology and in vitro antifungal susceptibility of Trichophyton schoenleinii, agent of tinea capitis favosa. 38
30597639 2019
3
Revival of favus in Japan caused by Trichophyton schoenleinii. 38
30768822 2019
4
Molecular Networking Reveals Two Distinct Chemotypes in Pyrroloiminoquinone-Producing Tsitsikamma favus Sponges. 38
30654589 2019
5
Teigne Tondante and Mahon Brothers: Two Laymen "Physicians" of Hôpital Saint-Louis, Paris. 38
30505803 2018
6
The extract of Polygoni Cuspidati Rhizoma et Radix suppresses the vascular endothelial growth factor-induced angiogenesis. 38
29655679 2018
7
Chemically characterized Mentha cardiaca L. essential oil as plant based preservative in view of efficacy against biodeteriorating fungi of dry fruits, aflatoxin secretion, lipid peroxidation and safety profile assessment. 38
28552513 2017
8
In Vitro Antifungal Susceptibility Profiles of 12 Antifungal Drugs against 55 Trichophyton schoenleinii Isolates from Tinea Capitis Favosa Patients in Iran, Turkey, and China. 38
27956429 2017
9
A revision of the family Ameroseiidae (Acari, Mesostigmata), with some data on Slovak fauna. 38
29118608 2017
10
Tinea capitis caused by Trichophyton rubrum mimicking favus. 38
28099533 2016
11
The complete mitochondrial genome of Mastacembelus aculeatus (Cypriniformes, Mastacembelidae) from the Pearl River, China. 38
26641140 2016
12
Disseminated Favus Caused by Microsporum gypseum in a Patient with Systemic Lupus Erythematosus. 38
26259050 2016
13
Leprosy in the Bible. 38
26773616 2016
14
[A recurrent case of adult favus successfully treated with terbinafine]. 38
26649420 2015
15
Generalized favus: the story of a legendary case of tinea favosa. 38
25583289 2015
16
Evolution of tinea capitis in the Nanchang area, Southern China: a 50-year survey (1965-2014). 38
25756741 2015
17
Use of UHPLC high-resolution Orbitrap mass spectrometry to investigate the genes involved in the production of secondary metabolites in Aspergillus flavus. 38
26278397 2015
18
Goya and tinea favosa. 38
25387510 2014
19
[Epidemiology of Tinea capitis in the suburbs of Tipasa, Algeria]. 38
24746723 2014
20
Cat favus caused by Microsporum incurvatum comb. nov.: the clinical and histopathological features and molecular phylogeny. 38
24625676 2014
21
Clinical types of tinea capitis and species identification in children: an experience from tertiary care centres of Karachi, Pakistan. 38
24864605 2014
22
The presence of biomarker enzymes of selected Scleractinian corals of Palk Bay, southeast coast of India. 38
25215288 2014
23
Robert Remak (1815-1865): discoverer of the fungal character of dermatophytoses. 38
24312990 2013
24
Tinea infection with scutula-like lesions caused by Microsporum gypseum in a SLE patient: case report and literature review. 38
23912467 2013
25
Favus in an elderly Kashmiri female: A rare occurrence. 38
24082227 2013
26
Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb.et Zucc.: a review. 38
23707210 2013
27
Human pathogenic fungus Trichophyton schoenleinii activates the NLRP3 inflammasome. 38
23686720 2013
28
Pitfall scarring alopecia: favus closely mimicking lichen planus. 38
23294414 2013
29
Species-specific responses of corals to bleaching events on anthropogenically turbid reefs on Okinawa Island, Japan, over a 15-year period (1995-2009). 38
23565291 2013
30
[Tinea capitis in the University Hospital of Constantine (Algeria)]. 38
23518171 2012
31
Diversity of bacterial communities associated with the Indian Ocean sponge Tsitsikamma favus that contains the bioactive pyrroloiminoquinones, tsitsikammamine A and B. 38
22310802 2012
32
Tinea capitis favosa misdiagnosed as tinea amiantacea. 38
24432210 2012
33
The taxonomic status of Trichophyton quinckeanum and T. interdigitale revisited: a multigene phylogenetic approach. 38
22587727 2012
34
Molecular phylogeny of the Robust clade (Faviidae, Mussidae, Merulinidae, and Pectiniidae): an Indian Ocean perspective. 38
22705823 2012
35
[Mycological and epidemiological aspects of tinea capitis in the Sousse region of Tunisia]. 38
21893228 2011
36
A novel method for coral explant culture and micropropagation. 38
20700752 2011
37
[Epidemiology of tinea capitis in outpatients at the Children's Hospital in Rabat (Morocco)]. 38
24451494 2011
38
Favus of the scalp: an overview and update. 38
20411336 2010
39
Tinea capitis in Southeastern China: a 16-year survey. 38
19936963 2010
40
Historical aspects of dermatomycoses. 38
20347652 2010
41
Inflammatory tinea capitis: kerion, dermatophytic granuloma, and mycetoma. 38
20347653 2010
42
Intraspecific variation and interspecific differences in the bacterial and fungal assemblages of blue tit (Cyanistes caeruleus) and great tit (Parus major) nests. 38
19830477 2010
43
[Dermatophytosis: a summary of dermatomycosis as a proposal for future revision of the guidelines]. 38
19942789 2009
44
[Tinea favosa]. 38
18558061 2008
45
"Air, sun, water": ideology and activities of OZE (Society for the Preservation of the Health of the Jewish Population) during the interwar period. 38
19230337 2008
46
Scalp demodicidosis mimicking favus in a 6-year-old boy. 38
17637363 2007
47
Tinea capitis favosa due to Trichophyton schoenleinii. 38
17992453 2007
48
Atypical favic invasion of the scalp by Microsporum canis: report of a case and review of reported cases caused by Microsporum species. 38
17305783 2007
49
The first description of an oesophageal candidosis by Bernhard von Langenbeck in 1839. 38
16784441 2006
50
[Tinea capitis in department of dermatology and venerology in the University hospital of Donka at Conakry, Guinea]. 38
16568680 2006

Variations for Tinea Favosa

Expression for Tinea Favosa

Search GEO for disease gene expression data for Tinea Favosa.

Pathways for Tinea Favosa

Pathways related to Tinea Favosa according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.67 NLRP3 MAPK8 CTSB CASP1
2
Show member pathways
12.25 MAPK8 KDR KALRN
3
Show member pathways
12.23 NOS3 MAPK8 KDR
4
Show member pathways
12.07 NOS3 MAPK8 KDR
5
Show member pathways
12.06 NOS3 MAPK8 KDR
6
Show member pathways
11.78 NLRP3 MAPK8 CASP1
7
Show member pathways
11.74 MAPK8 KDR CASP1
8
Show member pathways
11.74 NLRP3 MAPK8 CASP1
9
Show member pathways
11.69 NOS3 MAPK8 KDR
10 11.47 NOS3 MAPK8 KDR
11 11.38 NOS3 MAPK8
12 11.11 NLRP3 CASP1
13
Show member pathways
11.05 NOS3 MAPK8 KDR
14 10.93 MAPK8 CHD7
15 10.78 NOS3 KDR
16 10.68 NLRP3 MAPK8 CASP1

GO Terms for Tinea Favosa

Cellular components related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NLRP3 inflammasome complex GO:0072559 8.62 NLRP3 CASP1

Biological processes related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to cytokine stimulus GO:0071345 9.4 MAPK8 CASP1
2 positive regulation of blood vessel endothelial cell migration GO:0043536 9.37 NOS3 KDR
3 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 9.32 NLRP3 CASP1
4 cellular response to organic substance GO:0071310 9.26 MAPK8 CASP1
5 blood vessel remodeling GO:0001974 9.16 NOS3 CHD7
6 positive regulation of interleukin-1 beta secretion GO:0050718 8.96 NLRP3 CASP1
7 cellular response to lipopolysaccharide GO:0071222 8.8 NLRP3 MAPK8 CASP1

Molecular functions related to Tinea Favosa according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ATP binding GO:0005524 9.02 NLRP3 MAPK8 KDR KALRN CHD7

Sources for Tinea Favosa

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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