MCID: TNN001
MIFTS: 28

Tinea Nigra

Categories: Infectious diseases

Aliases & Classifications for Tinea Nigra

MalaCards integrated aliases for Tinea Nigra:

Name: Tinea Nigra 12 15 32
Microsporosis Nigra 12 71
Infection by Cladosporium Werneckii 12
Keratomycosis Nigricans 12
Tinea Palmaris Nigra 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8912
ICD9CM 34 111.1
SNOMED-CT 67 1022006
ICD10 32 B36.1
UMLS 71 C0152067

Summaries for Tinea Nigra

Disease Ontology : 12 A superficial mycosis that is a superficial fungal infection of the skin characterized by brown to black macules which usually occur on the palmar aspects of hands and occasionally the plantar and other surfaces of the skin, caused by Hortaea werneckii, which is a common saprophytic fungus believed to occur in soil, compost, humus and on wood in humid tropical and sub-tropical regions.

MalaCards based summary : Tinea Nigra, also known as microsporosis nigra, is related to superficial mycosis and dermatomycosis. An important gene associated with Tinea Nigra is POLR2B (RNA Polymerase II Subunit B), and among its related pathways/superpathways are Ion channel transport and Synaptic vesicle cycle. Affiliated tissues include skin, and related phenotypes are Decreased influenza A H1N1 (A/Hamburg/04/2009) virus numbers and Decreased influenza A H1N1 (A/WSN/33) virus numbers

Wikipedia : 74 Tinea nigra, also known as superficial phaeohyphomycosis and Tinea nigra palmaris et plantaris, is a... more...

Related Diseases for Tinea Nigra

Diseases related to Tinea Nigra via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 24)
# Related Disease Score Top Affiliating Genes
1 superficial mycosis 30.6 POLR2B ENSG00000202479
2 dermatomycosis 30.2 POLR2B ENSG00000202479
3 dermatophytosis 11.0
4 fungal infectious disease 10.2
5 black piedra 10.1
6 white piedra 10.1
7 acral lentiginous melanoma 10.1
8 pityriasis versicolor 10.1
9 eumycotic mycetoma 10.1 POLR2B ENSG00000202479
10 external ear disease 10.0 POLR2B ENSG00000202479
11 dowling-degos disease 1 10.0
12 otomycosis 10.0
13 tinea cruris 10.0
14 tinea corporis 10.0
15 phaeohyphomycosis 10.0
16 melanoma 10.0
17 contact dermatitis 10.0
18 allergic contact dermatitis 10.0
19 skin disease 10.0
20 peritonitis 10.0
21 lichen planus 10.0
22 superficial spreading melanoma 10.0
23 otitis externa 10.0 POLR2B ENSG00000202479
24 blastomycosis 9.7 GPR85 CABP1

Graphical network of the top 20 diseases related to Tinea Nigra:



Diseases related to Tinea Nigra

Symptoms & Phenotypes for Tinea Nigra

GenomeRNAi Phenotypes related to Tinea Nigra according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased influenza A H1N1 (A/Hamburg/04/2009) virus numbers GR00195-A-3 8.96 ATP6V0D1 ATP6V1A
2 Decreased influenza A H1N1 (A/WSN/33) virus numbers GR00195-A-2 8.62 ATP6V0D1 ATP6V1A

Drugs & Therapeutics for Tinea Nigra

Search Clinical Trials , NIH Clinical Center for Tinea Nigra

Genetic Tests for Tinea Nigra

Anatomical Context for Tinea Nigra

MalaCards organs/tissues related to Tinea Nigra:

40
Skin

Publications for Tinea Nigra

Articles related to Tinea Nigra:

(show top 50) (show all 163)
# Title Authors PMID Year
1
Tinea Nigra: Dermoscopic Findings. 61
33493481 2021
2
Tinea nigra palmaris-associated peritonitis, caused by Hortaea werneckii: The first case report in a peritoneal dialysis patient. 61
32783526 2020
3
Entodermoscopy in the Diagnosis of Tinea Nigra: Two Case Reports. 61
32685278 2020
4
Interdigital Tinea Nigra. 61
32391228 2020
5
[First autochthonous case report of tinea nigra in Chile]. 61
31348769 2019
6
In vitro activity of nine antifungal agents against a global collection of Hortaea werneckii isolates, the agent of tinea nigra. 61
31071468 2019
7
Case of tinea nigra on the sole: Correspondences between dermoscopic and histological findings. 61
30549086 2019
8
Tinea nigra mimicking acral melanocytic nevi. 61
31700803 2019
9
The extremely halotolerant black yeast Hortaea werneckii - a model for intraspecific hybridization in clonal fungi. 61
32647617 2019
10
Tinea nigra: Report of three pediatrics cases. 61
30571825 2018
11
Fungal diseases in children and adolescents in a referral centre in Bogota, Colombia. 61
29601109 2018
12
Reflectance confocal microscopy for the diagnosis of tinea nigra. 61
29283186 2018
13
Tinea nigra palmaris: a clinical case in a rural Ethiopian hospital. 61
30231166 2018
14
Reflectance confocal microscopy of tinea nigra: comparing images with dermoscopy and mycological examination results. 61
28954116 2017
15
White piedra, black piedra, tinea versicolor, and tinea nigra: contribution to the diagnosis of superficial mycosis. 61
29186263 2017
16
Tinea nigra: A diagnostic pitfall. 61
27846967 2016
17
Superficial Phaeohyphomycosis Caused by Aureobasidium melanogenum Mimicking Tinea Nigra in an Immunocompetent Patient and Review of Published Reports. 61
26883514 2016
18
Tinea nigra dermoscopy: A useful assessment. 61
27185451 2016
19
Entodermoscopy: a spotlight on tinea nigra. 61
26566884 2016
20
Tinea nigra on the fingers. 61
26643182 2015
21
Dermatoscopy in inflammatory and infectious skin disorders. 61
26333553 2015
22
Bilateral Tinea Nigra Plantaris with Good Response to Isoconazole Cream: A Case Report. 61
26594169 2015
23
Tinea nigra showing a parallel ridge pattern on dermoscopy. 61
25766573 2015
24
Tinea nigra presenting speckled or "salt and pepper" pattern. 61
24898980 2014
25
Scanning electron microscopy of tinea nigra. 61
24770516 2014
26
[The value of dermoscopy in the diagnosis of tinea nigra]. 61
24507218 2014
27
Bilateral Tinea Nigra of palm: a rare case report from Eastern India. 61
24399400 2014
28
A case of Tinea nigra associated to a bite from a European rabbit (Oryctolagus cuniculus, Leporidae): the role of dermoscopy in diagnosis. 61
24626667 2014
29
[Tinea nigra in an unusual anatomic location]. 61
23567657 2013
30
Palmar lichen planus mimicking tinea nigra. 61
24082209 2013
31
Dermoscopy for the pediatric dermatologist part I: dermoscopy of pediatric infectious and inflammatory skin lesions and hair disorders. 61
23405886 2013
32
Double-blind study with topical Isoconazole and Terbinafine for the treatment of one patient with bilateral Tinea nigra plantaris and suggestions for new differential diagnosis. 61
23563768 2013
33
[Tinea nigra: a allochthonous case report in Chile]. 61
23450418 2013
34
Dermoscopy revealing a case of Tinea Nigra. 61
23539019 2013
35
Identification of Hortaea werneckii Isolated from mangrove plant Aegiceras comiculatum based on morphology and rDNA sequences. 61
22864562 2012
36
Tinea nigra: successful treatment with topical butenafine. 61
23197223 2012
37
Hortaea werneckii isolated from silicone scuba diving equipment in Spain. 61
22548240 2012
38
Subcutaneous phaeohyphomycosis (mycotic cyst). 61
22682192 2012
39
Tinea nigra and dermoscopy. 61
22309345 2012
40
Spontaneous cure in a case of Tinea nigra. 61
22481674 2012
41
Dermoscopy improves diagnosis of tinea nigra: a study of 50 cases. 61
21834814 2011
42
What is your diagnosis? Tinea nigra. 61
21699123 2011
43
Tinea nigra in geographical forms of "heart" and "parrot beak". 61
21603833 2011
44
Study of the dermatoscopic pattern of tinea nigra: report of 6 cases. 61
21413646 2010
45
Historical aspects of dermatomycoses. 61
20347652 2010
46
Tinea versicolor, tinea nigra, white piedra, and black piedra. 61
20347655 2010
47
Tinea nigra: a rare imported infection. 61
19552720 2010
48
What is your diagnosis? Tinea nigra. 61
20166569 2009
49
A case report of tinea nigra from North India. 61
19736456 2009
50
Cladophialophora saturnica sp. nov., a new opportunistic species of Chaetothyriales revealed using molecular data. 61
18720218 2009

Variations for Tinea Nigra

Expression for Tinea Nigra

Search GEO for disease gene expression data for Tinea Nigra.

Pathways for Tinea Nigra

Pathways related to Tinea Nigra according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.29 SLC9B1 ATP6V1A ATP6V0D1
2
Show member pathways
11.27 ATP6V1A ATP6V0D1
3 10.92 ATP6V1A ATP6V0D1

GO Terms for Tinea Nigra

Biological processes related to Tinea Nigra according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ion transmembrane transport GO:0034220 9.5 SLC9B1 ATP6V1A ATP6V0D1
2 insulin receptor signaling pathway GO:0008286 9.43 ATP6V1A ATP6V0D1
3 regulation of macroautophagy GO:0016241 9.4 ATP6V1A ATP6V0D1
4 cellular iron ion homeostasis GO:0006879 9.37 ATP6V1A ATP6V0D1
5 transferrin transport GO:0033572 9.26 ATP6V1A ATP6V0D1
6 phagosome acidification GO:0090383 9.16 ATP6V1A ATP6V0D1
7 proton transmembrane transport GO:1902600 9.13 SLC9B1 ATP6V1A ATP6V0D1
8 cellular response to increased oxygen levels GO:0036295 8.62 ATP6V1A ATP6V0D1

Molecular functions related to Tinea Nigra according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proton-transporting ATPase activity, rotational mechanism GO:0046961 8.62 ATP6V1A ATP6V0D1

Sources for Tinea Nigra

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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